LOCUS       gnlProkkaLENEAMHB_19    1737 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LENEAMHB_19.
ACCESSION   gnlProkkaLENEAMHB_19
VERSION     gnlProkkaLENEAMHB_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:25:54
            Original ID  :: gnl|Prokka|LENEAMHB_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1737
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1737
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:1737]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1737
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..1737
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1737
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             1..1737
                     /NRPS_PKS="Domain: AMP-binding (40-428). E-value: 2.9e-106.
                     Score: 347.3. Matches aSDomain:
                     nrpspksdomains_ctg19_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (533-575). E-value: 2.5e-18. Score:
                     58.0. Matches aSDomain: nrpspksdomains_ctg19_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     349.3; E-value: 4.8e-106)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_1"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-116, bitscore:
                     373.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-12, bitscore:
                     32.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNQPLSSLSLVTETEKQALLEAWKGKALPVPTDKTVHQLFEETV
                     QRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPDDRVGILTKPSLEMSAAVLG
                     VLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSYTGDVILLDGSRTILS
                     LPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVNLCFWHHDAFSMTAE
                     DRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIVRLNDYFETNGVTITFLPTQ
                     LAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPTENTVVATSAEIHPEEGSLS
                     IGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREGETAKRFVADPFVPGE
                     RMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTAVKDK
                     GGNTAIAAYVTPETADIEALKSALKETLPDYMIPAFWVTLNELPVTANGKVDRKALPDP
                     DIEAGSGEYKAPTTDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQH
                     GWK"
     aSDomain        121..1284
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg19_1_AMP-binding.1"
                     /evalue="2.90E-106"
                     /label="ctg19_1_AMP-binding.1"
                     /locus_tag="ctg19_1"
                     /protein_end="428"
                     /protein_start="40"
                     /score="347.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD
                     DRVGILTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV
                     PDSYTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEH
                     HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIV
                     RLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT
                     ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL
                     NREGETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     aSModule        121..1725
                     /complete
                     /domains="nrpspksdomains_ctg19_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg19_1_PCP.1"
                     /locus_tags="ctg19_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       307..348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0001"
                     /evalue="5.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg19_1"
                     /protein_end="116"
                     /protein_start="102"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       550..609
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0002"
                     /evalue="3.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg19_1"
                     /protein_end="203"
                     /protein_start="183"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       949..978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0003"
                     /evalue="3.00E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg19_1"
                     /protein_end="326"
                     /protein_start="316"
                     /score="10.2"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       1081..1170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0004"
                     /evalue="6.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg19_1"
                     /protein_end="390"
                     /protein_start="360"
                     /score="50.5"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREGETAKRF"
     CDS_motif       1249..1314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0005"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg19_1"
                     /protein_end="438"
                     /protein_start="416"
                     /score="36.6"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        1600..1725
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg19_1_PCP.1"
                     /evalue="2.50E-18"
                     /label="ctg19_1_PCP.1"
                     /locus_tag="ctg19_1"
                     /protein_end="575"
                     /protein_start="533"
                     /score="58.0"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQ"
ORIGIN
        1 aacccgaacc agccgctttc cagcctgtca ctggtcaccg agacagaaaa gcaagcgctt
       61 cttgaggcat ggaagggcaa ggcgctgcct gtgccgacag acaaaacagt tcatcagcta
      121 ttcgaagaga ctgtccagcg ccacaaagac cgcccggctg tcacatacaa cggccaatct
      181 tggacgtacg gcgagctgaa tgcgaaggca aaccgtctcg cgcggattct gatggactgc
      241 ggcatcagcc cggatgaccg cgtcggcatt ctcacgaagc cgtcgcttga aatgtccgcc
      301 gcggtgctcg gcgtcttgaa agccggagcg gcgtttgtgc cgattgatcc tgactacccg
      361 gatcagcgga ttgagtatat tttacaggac agcggcgcga agctcctctt gaaacaggaa
      421 ggcatttcag tgccggacag ctatacggga gatgtcattc ttctcgacgg aagccgcacg
      481 attctaagcc tgccgcttga tgaaaacgac gagggaaatc cagagacggc tgtaaccgcg
      541 gagaacttgg cgtacatgat ttacacgtct ggaacgaccg gacagccgaa gggtgtcatg
      601 gtcgagcacc atgcgcttgt gaacctgtgc ttctggcacc acgacgcgtt cagcatgaca
      661 gcggaggacc gcagtgcgaa gtacgcgggc ttcgggttcg acgcttccat ttgggagatg
      721 ttcccgacct ggacgatcgg tgctgaactt cacgtcattg atgaagcgat ccgcctcgat
      781 atcgtccgcc tgaacgatta ttttgaaacg aacggcgtaa cgatcacgtt cctgccgaca
      841 cagcttgcgg aacagttcat ggagcttgag aacacatcac ttcgcgtcct cttgaccgga
      901 ggagacaagc tgaagcgcgc agtgaaaaag ccgtacacac tcgtcaacaa ctacgggccg
      961 acagaaaata cggtcgttgc cacaagcgca gaaatccatc cggaggaagg ctcgctttcc
     1021 atcggaaggg ccattgccaa tacgagagta tacattctcg gcgagggcaa tcaggtgcag
     1081 ccggaaggcg tagccggaga gctttgcgtg gcggggcgcg gactggcacg cggctatctg
     1141 aatcgagaag gcgaaaccgc gaagcggttt gtcgctgatc cgtttgtgcc gggtgagcgc
     1201 atgtaccgca ccggcgattt ggtgaaatgg acgggcggcg gcatcgaata catcggccgg
     1261 atcgaccagc aggtcaaggt ccgcggctac cggatcgagc tttcagaaat tgaagtccag
     1321 ctcgcccagc tttctgaggt gcaggatgcg gcggtgacag ctgtcaagga taaaggcggc
     1381 aatacagcaa tcgcggcgta tgtcacaccg gaaacagctg acatagaagc actaaaatca
     1441 gcactaaagg aaaccctgcc ggattacatg atcccggcgt tctgggtgac gctgaacgag
     1501 cttccggtta cggcaaacgg caaagtggac cgcaaagcct tgcctgaccc ggacatcgaa
     1561 gcgggaagcg gagaatacaa agcgccgacg accgacatgg aagagctgct tgccggcatc
     1621 tggcaggacg tgcttggaat gtctgaagtc ggtgtcaccg acaatttctt ctcgcttggc
     1681 ggagattcca tcaaaggaat tcaaatggcg agccgcttga accagcacgg ctggaag
//
