LOCUS       gnlProkkaJEGGKGOF_12   15414 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEGGKGOF_12.
ACCESSION   gnlProkkaJEGGKGOF_12
VERSION     gnlProkkaJEGGKGOF_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:35:48
            Original ID  :: gnl|Prokka|JEGGKGOF_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 36065
            Orig. end    :: 51479
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15414
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:14639]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..14639
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15414
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15414
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             113..319
                     /locus_tag="ctg12_34"
                     /transl_table=11
                     /translation="MRERGQVWSYSEVKRESQLVNYNTDGRYLSEATNFELYNFVREYK
                     TSDEIRRIWNPKKDESVIHDKDN"
     CDS             507..2264
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 390; E-value:
                     3.3e-118)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_35"
                     /transl_table=11
                     /translation="MFFKESIIAKLWWFFKLEKRRYIVGILALSLVSVLNLIPPMVMGR
                     VIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLVAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFEKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIETLLEQESDVQDPAYPLPSIENGRL
                     DFAIDRFAFEDEDTLRDIHFTLDKGQTLGLVGPTGSGKTALVKLLLREHDVNQGAIYLN
                     GHDIRDYRLSDLRSLIGYVPQDQFLFASSILDNVRFGNPDFSIDKVEEATKLAQVYDDI
                     KDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILNPEILILDDSLSAVDAKTEHAIIDN
                     LKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGRHDDLLAQGGWYAKTYESQQL
                     EMEGGEAHA"
     CDS             2257..4002
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     282.9; E-value: 3.2e-86)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 312.2; E-value:
                     1.2e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_36"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTFIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGTLSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRL
                     KKEFDGINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFNPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNV
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLL
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGHIIEHGSHEDLLALGGTYHKMYSLQAG
                     AMEGE"
     CDS             5001..7169
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 309.9; E-value: 6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_37"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.1e-45, bitscore:
                     145.1, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1103.9,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGFGMFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRE
                     LAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYV
                     IYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFL
                     PLIFKQRFLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYV
                     LQQMMTFARDYLLTILSQRLTIDVILSYIRHIFELPMSFFATRRTGEVISRFSDANSII
                     DALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTLIVFAFMKPFERMNHD
                     VMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSL
                     KQGAQLILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKV
                     ANTRLNEVYLIESEFGQSDDTYQEGIADGDITVTDLSYKYGFGRDTLTDVSLTIRQGEK
                     ISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHINYLPQQSYIFS
                     GSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIA
                     LARALLTKSPVLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVV
                     IDQGRVVETGSHQDLMSYPGFYYQLFRK"
     CDS             7185..8552
                     /locus_tag="ctg12_38"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAEIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVATYDNSDSTKKEALKNQF
                     LQNAGQQLISVETQITDAESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             8567..8728
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_39"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.1e-08,
                     bitscore: 27.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGRQRTLPT
                     KDYNIPQV"
     CDS             complement(8746..10086)
                     /locus_tag="ctg12_40"
                     /transl_table=11
                     /translation="MLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLAF
                     NFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLITF
                     FIFPFFNISITDYKSSLLISIPSSIAPLCLSFLFIKLFKESFTILQKQKSNSPIQHIII
                     VANFFMFGYTLLLQSLMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNICEMIQG
                     QLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEVYDS
                     VLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGME
                     ILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFER
                     GVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(10080..10949)
                     /locus_tag="ctg12_41"
                     /transl_table=11
                     /translation="MYIVSKIQKKKKSHFPLIKKLKSRFLYVTIFSINSIRHEREDSTL
                     RIYLLEDNHIQMGRLEEAVAHELKSFGKDLSCVHSFDKPDQLLSAITSNTSDQVFFLDI
                     EIKGEDKKGLNIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAYKYIDKTLDEASFRKE
                     IGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDIKHHVHLQTIYTLIDI
                     RANLADLKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQI
                     VEERGRGC"
     CDS             11074..11250
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_42"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.7e-12,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             11269..11469
                     /locus_tag="ctg12_43"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTAGMTIVGAAFFG
                     IAGAGTGFAGGSTAFCYGTAE"
     CDS             11495..11650
                     /locus_tag="ctg12_44"
                     /transl_table=11
                     /translation="MKKYLIIFSTIAMIYLYSKVLLSSGNIYQLLLASIGFFFFLFGVY
                     RQYRKK"
     CDS             11825..12067
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_45"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.2e-17,
                     bitscore: 53.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGGCSWRGAGGATVQGAIGGAFGG
                     NVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             12268..12456
                     /locus_tag="ctg12_46"
                     /transl_table=11
                     /translation="MITELTYNDLETIQGGVSCIMPRTNNKAGGSYDPFIDGRVSPPRY
                     RSGEAYPMVYLPICVLM"
     CDS             12653..12883
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_47"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.5e-18,
                     bitscore: 58.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTMNNFETLDLEALANVEGGGCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             12890..13015
                     /locus_tag="ctg12_48"
                     /transl_table=11
                     /translation="MFDLKSYILGMVSMAVMSFLDKPIMSFLEKHKATNSVKKKS"
     CDS             13103..13276
                     /locus_tag="ctg12_49"
                     /transl_table=11
                     /translation="MTKKRLVSLMMSMGFVLVSLHNFGEKLNFGLQCLNLIGLCLFLFL
                     MCTVIKDIRSDK"
     CDS             13748..14149
                     /locus_tag="ctg12_50"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLAV
                     GALAFGVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFLIITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             14400..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_51"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.8e-13,
                     bitscore: 41.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTMNNFETLDLEALASVEGGRVNWERWGMCGASVAVGASEGF
                     SAAAGGTAFFIGPYAIGTGAVGAAIGGGVALLGC"
     CDS             14651..15043
                     /locus_tag="ctg12_52"
                     /transl_table=11
                     /translation="MTHRVSKRDIVLFVIAQVVSISLLVLFFSQLLHNLSSVFQLVYIV
                     AALLVVVVDILLIRKIMTRREEPTVLNQLKASLACFLLLTLSCLRFLTTDFYYQKVIAI
                     FVGFFSLLGFVLFLWGIKYINHNIEK"
     CDS             15072..15251
                     /locus_tag="ctg12_53"
                     /transl_table=11
                     /translation="MFTKLTHNDLEVIQGGAVCLMPNVNNKEGDPLKDGWVSPPRYRSG
                     EAYPMVYLPVCAIM"
ORIGIN
        1 tagtgaaaca atgaaacact taatgtgaca gtagtcaccg tattgacact aggagcaaca
       61 atgacaacgg ttaaagcaga tacttatcaa aagtggccgt gatgccgata ttatgcgaga
      121 aagagggcag gtttggagct attctgaggt taagagagag tctcaattag ttaactacaa
      181 cactgatggt cgctatctca gtgaggcaac taacttcgaa ttgtacaatt ttgtcagaga
      241 gtataagaca tctgatgaaa ttagacgtat ttggaaccct aagaaggacg aatcagttat
      301 ccacgataag gataactgat tctattgatg atgggcacaa ggcctataat tttgactcct
      361 ttgcttatca attgccagag tctactgatt ttggaaaatt gacttatatt ggtcactttc
      421 agttagaaga tggtacaatt tatcgctatt ggaaataact ttcattagac ttataatcat
      481 ccttttgtag ggataggggg aataacttgt tttttaaaga atcaatcatt gcaaaacttt
      541 ggtggttttt caagttagaa aaacgtcgtt atattgttgg gatattggca ctgagtttgg
      601 tttcggttct taatctgatt cctcctatgg ttatgggtcg ggtcattgat gctatcacat
      661 cgggaaaatt gaccaatcag atcttgcttt tgaatctcgt ttatttgctt ttggcggctt
      721 taggaatgta ctatttgcgc tatgtttggc ggatgtatat cttggcaacg tcttatcgct
      781 tgggacagat tatgcgttca cggctttttg agcattttac caagatgtcg ccttcttttt
      841 accaaaagta ccgaactggt gatctcatgg cccatgccac caatgatatc aactctctaa
      901 cccgtttggc tggtgggggt gtcatgtcag ccgtggatgc gtctatcaca gccttggtga
      961 ctttaatcac catgttcttc agcatttcct ggcagatgac cctggtagca gtcttacctc
     1021 tacctttcat ggcttttgcg actagtcgtt tgggacgtaa gacccacaaa gcttttggag
     1081 aatcccaggc agctttttct gaacttaata ataaggtaca agaatcggtg tcaggtatca
     1141 aggtaaccaa gtcttttggc tatcaggagg ctgagctcca gtccttccaa gagaccaata
     1201 agatgacttt tgaaaagaat atgcatacca tgaagtatga cagccttttt gatcctttgg
     1261 tcttgctctt tgttggctca tcttatgttt tgaccctcct tgtcggggcc tttatgattc
     1321 aggccggtca gataacggtc ggaaatttgg taacctttat tacctatttg gacatgctgg
     1381 tttggcccct aatggccatt ggcttcctct ttaatatcac gcagagggga aatgtgtcct
     1441 accaacgtat cgagactctt ttagagcagg aatcagatgt tcaagatcct gcttatcctc
     1501 ttccaagcat tgaaaatggt cgtttagact ttgcgattga ccgctttgct tttgaggatg
     1561 aggatacttt gcgagatatt catttcacct tggacaaggg gcaaaccctt ggtttggttg
     1621 gaccgactgg ctcaggaaag acggctcttg tcaagttgct cttgcgggag cacgatgtca
     1681 atcaaggagc tatctatttg aatggacatg acatccgaga ctatcgccta tcagacttgc
     1741 gtagcttgat tggttatgtt cctcaagacc agtttctctt tgccagttct attttagaca
     1801 atgtccgctt tggtaatcca gatttctcca ttgataaggt ggaagaagcg actaagttag
     1861 ctcaagttta tgatgatatc aaggatatgc ctgaaggctt tgaaacaatc attggtgaaa
     1921 agggtgtcag cctatcaggt ggtcaaaaac aacgtctggc tatgagccgg gccatgattt
     1981 tgaatccaga aattttgatt ttggatgact ccttatctgc ggttgatgct aagacagaac
     2041 atgccattat tgataatctt aagcatactc gcaaggacaa aacaactatt attaccgccc
     2101 accgtctcag tgcggtggtg cacgctgacc tcatcctggt catgcaagat ggtcgtatca
     2161 ttgaacgtgg gcgtcatgac gacttactag ctcaaggtgg ttggtatgcc aagacctatg
     2221 agtctcaaca gttagaaatg gaaggaggag aagctcatgc ctaatcaaaa ccaatggtct
     2281 gtgtttaagc gtctcttgac ctatctcaag ccttacaagt tcttgacctt tctagctttg
     2341 accttcctct tgtccacaac gtttatcaag agtatcattc ccttggtggc ctcttatttt
     2401 attgatcact atcttcatga tatgaatcag gcggcaagta tgattctgat tggctactat
     2461 ggtctctacc tcttgcagac actagtccag tatctgggaa atctcttctt tgcgcgtgtg
     2521 tcctatagca ttgtcagaga tattcgtcga gatgcctttg ccaatatgga aaaactgggt
     2581 atgtcttact ttgacaagac cccagcaggt tccatcgttt cccgcttgac caatgatact
     2641 gagaccatta gcgagatgtt ctcaggaact ctgtctagtt ttatttcagc tatctttatc
     2701 tttgttacca ccctttacac catgatgatc ttggacattc gtctgaccgg gcttattgtc
     2761 ctctttcttc ctctgattgt ccttttggtt aacctttatc gcaaaaaatc agtggtcatc
     2821 attgaaaaga ccagagcctt gctttcagat ataaatgcca aactgtcaga gagtatcgaa
     2881 gggattcgca tcattcaggc ctttaaccag gagaagcgtc ttaaaaaaga gtttgatggc
     2941 attaatgagg aacacctgat ttatgccagc cgttctatat cactggattc tctctttcta
     3001 cgcccagcca tgagtctact gaagctcctg gcttatgctg ttctcatggc ctattttggc
     3061 taccgaggta tctatctggg tatcacagca gggaccatgt atgcctttat ccagtatatt
     3121 aatcgcctct ttaatccctt gattgaagtg acacaaaact tctcgactct acaaacctct
     3181 atggtctcag caggtcgggt ctttgccttg attgacgagc gtacctatga gcctgaacag
     3241 agagacacag ctgccaaggt tactgagggg aatgttcgct ttgagaatgt ctccttctcc
     3301 tatgatggca agcaccagat tttggataat atttccttct ctgtcaataa aggtgaaacc
     3361 atcgcctttg tgggatctac aggctctgga aaatcctcta ttatcaacgt gctcatgcga
     3421 ttctatgagt tccaatcagg acgagttctc ctagacggtg tggatattcg tgattatagt
     3481 caggcagagc tgcgcaagaa tattggtctt gtccttcagg accccttcct ctatcatggc
     3541 acaatcaaat ccaatattgc catgtatcaa gatttaactg atgaagagat taaagctgct
     3601 gctgagtttg tcgatgccaa tcactttatt gataaacttc ctgaaggcta tgattcccca
     3661 gtttccgaac gtggttcaag tttctcaacc ggtcaacgcc agcttctagc ctttgctaga
     3721 accgttgcta gccagcctaa aatcttgatt ttggatgaag cgacagccaa tattgattcg
     3781 gagacagagg ctattgttca aaactctctt gcaaaaatgc gtcaaggccg tacaaccatt
     3841 gccattgccc accgcctatc aacaatccaa gatgctaact gcatctatgt cttagacaag
     3901 ggccacatca ttgaacacgg tagccacgaa gatctcctag ccctcggcgg cacctatcac
     3961 aagatgtaca gcctacaagc aggcgccatg gaaggagagt aagctgatct agaccatagc
     4021 ttctatattc gaaaagattt cttaaaaatc aaaatcgagt agtgacattt atgtcactac
     4081 ttttttgttg gctaccaccc tataataaaa tcatagcttg agagaaaaag ctaaaaataa
     4141 tttaggaggt tgttagaatg acaaggcaaa caaataatac atttgaaaca ctcgatctcg
     4201 aggcacttgc aaacgttgag gtagtgtaaa ataagttgtg taaacacaaa aaggaataaa
     4261 tccgttatag tagagttgca aaacattact agaaagagat ttattcctat gactcagttt
     4321 accacagaac tacttaactt cggctctata atttctgtag tgggaaaaac cactgtagag
     4381 attatagagc tttttaagat ggtgccacct caaggttgag taaatcaaaa gatagaaggc
     4441 acaattactc aaggtggaaa taaggtgggc attaaggaag ggaacccctc tagtgacgct
     4501 aaaaatagca ttgacagtga taacaaatac acttacaaag ctaaggaaaa ttaaaccgat
     4561 aattgagtaa tcgaatctca agaggctgat ttagcctttt ttgataggat tttttgagat
     4621 atggattgac gtttttcata atgttatccc ctttcggaat aaaaataatc aaattatgac
     4681 atcatacgat agagataggc tccgaggcta tcagcagtca tggtttcctt tggaaatacc
     4741 agggctggca cagtaataat ggttagatca aatacgtatg cttgtaggac tattttagaa
     4801 tgtttccttc taataactat tgtataactt tgaaatcgat ttcaatgaac ttgtcctaaa
     4861 tgaccccaaa tacggcttga atggtaatag tggagatgac tttaagattt ttcttaccgt
     4921 ttgggacgta tggcaacttt ttgggacgct ggctcttttt atcctgaaaa tatgacatac
     4981 taatcatatg ataatttgtg atgaaagggt ttggtatgtt tcgttttcgt aggacttttg
     5041 tccctcaaat agacatgagg gattgtggag ttgctgcctt ggcatcagtg gccaagtact
     5101 atggttcaga ttattcatta gcacatctgc gtgagttggc gaagaccaat aaagaaggga
     5161 caactgcctt aggtcttgta gaggctgcta aaaaaattgg atttgaaacg agagctataa
     5221 aggctgaaat gtcgctcttt gagatggaag atgttcctta tccttttatt gctcatgtta
     5281 ataaagatgg gaagcttcaa cattattatg ttatttataa aagcaccaag gattatctga
     5341 taattggaga ccctgatcca agtgtaaaag taactaaaat gactaaagag cgttttgaga
     5401 aagagtggac aggtgttact ctttttatgg gaccggaacc cagttataaa ccacataagg
     5461 ataagaaaaa tggactctgg gactttctcc ctttgatctt taaacaaagg ttcttgatag
     5521 ctaatattgt ctttgccagt ctcttggtta ctttaataaa tattttaggt tcctattatt
     5581 tacaaggtat tctagacgaa tatgtcccta atcaaatgaa gtctacctta ggaattatct
     5641 caattggatt agttgtaacc tatgttttac aacaaatgat gacttttgca agagattatc
     5701 tcttaaccat actgagtcag cgattgacca ttgacgttat cttgtcctac atacgacata
     5761 tctttgaact cccaatgtct ttttttgcca caagacgtac aggggaggtt atctcacgtt
     5821 ttagtgatgc taactctatt atcgatgctc tggcttcgac gatattatca cttttccttg
     5881 atttctctat tgtgattatc gtaggaggcg tgttattgat acaaaatagc aatctcttca
     5941 agctagttct ttgttcggtt ccaatttata cccttatcgt ctttgccttt atgaaacctt
     6001 ttgagcgaat gaatcatgac gtcatgcaga gtaatgctat ggttaattca gccatcattg
     6061 aggacattaa tgggattgaa accataaagt cactaaccag cgaagaagta tgctatcaaa
     6121 agattgatgg tgagtttgtt gactatctag acaattcttt tcgcctttct aagttatcta
     6181 tactacaaac atcattgaaa caaggtgctc aacttatttt aaatgtactt atcctctgga
     6241 caggtgctca gttggtgatg ggaaatacca tttcgatagg acaattgatt acttttaata
     6301 tgttgctttc ctacttcacg aatcctttgg aaaatatcat taacctgcaa accaagttac
     6361 agtctgctaa ggtagctaat actaggctca atgaggtcta tctgattgaa tcagagtttg
     6421 gacaaagtga tgatacctat caagaaggca ttgcggatgg agatatcact gttacggatt
     6481 tatcttataa atatggtttt ggtcgtgata ctttgactga tgtcagtttg acgattagac
     6541 aaggagaaaa aatcagtttt gttggtgtca gtggatctgg taagactact ctagctaaaa
     6601 tgttggtcaa tttttatcaa ccatataagg ggcacataga ttttaatggt caaaatatta
     6661 gtcgcataga caagaaaact cttcgtcaac atattaacta cctccctcag caatcctata
     6721 tatttagtgg tagtgtttta gaaaatctta ctttaggtgc agcacggggt attacgcaag
     6781 ctgatatttt gaaagcttgt gaaatagcag aaattcgtca agatattgaa aacatgccta
     6841 tggggtttca gacagagctg tctgatggag caggtctgtc tggagggcaa aagcaacgta
     6901 tcgctttggc gcgtgcacta ctaacgaaat ctcctgtact aatcttagat gaagcaacta
     6961 gcggattgga tgttttgaca gaaaagcagg ttattgataa cctcctagca ctaaaagata
     7021 aaacgatcat ctttgtagca cacaggctta gtatcgctga gcggaccgac cgtatcgtag
     7081 tcattgatca gggacgcgta gtggagacag gttctcatca agacctgatg tcttatccag
     7141 gtttctatta tcaattattt agaaagtgag gaaaaggaaa cacgatgaat ccacagttgt
     7201 ttaaaagcac agagttttac catcgtcgct accacaatat gtctactgtt ttgattactc
     7261 ccttgatttt gttagttatt ttcctttttc ttttcgcttt ttttgctaag aaggaagtta
     7321 cagtcacgtc tagaggaagt atagagccaa ccaaggttat cgcagtaatc caatcaacca
     7381 gtgacaatac catcatagat aatcaactgg ttgctaataa ggttgttaaa aaaggggaca
     7441 ccttagttca gtattcagag accatggagg catcgcaaaa agaggggctt caaaagcaac
     7501 tagaactttt aaaaagacag gaatcaggtt tgaagacctt gcaatctagc ctaacgcagg
     7561 gaaccaatct tttccaagaa caggaagacg agtttggtta tcagagtact tttaacacct
     7621 acctaagtca ggcacaggat attgacttgg gtgtggctaa aacaaataca gaggttaata
     7681 accaagcaga aattgcgagt aataccggtt ctgctattga taaccagatt agtcaattgc
     7741 agactcaggt ctcagagtat gaggcgctct ctcaagctat taccaatcat gaaacgactt
     7801 tacctgaagg caatcctcat caggcaacct taaatgccta taacagtcag tatgctacga
     7861 caccggatgc cagtgtaaca gaccaatacc tatctcaagt taataccaat atttcgagct
     7921 tgaatgcttc cataggtaat ctagaaatcc aaaaggctgg gacaggcaca gttgcaactt
     7981 atgacaatag tgatagcact aaaaaagaag ctctaaaaaa tcaattcttg caaaatgcag
     8041 gacagcaatt gatctcagtg gaaacacaaa ttaccgatgc cgagagtaaa atcaatcagg
     8101 cagatgtcct tctgactaat accctcatcc agtcaccaga agatggaatc ttacacttga
     8161 gtcaagctga taaaaaagca accatggctg cgacaggaac tgagttggcc cagctttatc
     8221 ccgatatgac tcaaacccag gaagttgcca ttacttatta tgtgaattcg gattatgtgc
     8281 caaaactgca aaaaggccag tcagttcgac tgaccttgga taaggttggt aatcacggta
     8341 ccacaattat tggaaaactt gagagtattg ataattctgc cacggaaaca gaaaggggga
     8401 atgtgtttag agtaactgct agggcaagta tttcagaaaa agaagcccaa aatctacgtt
     8461 acggtctaga aggtcgtgtg acaagcgtta ttgaccaaaa gacctacttc aattacttta
     8521 aagacaagtt actaaacttg caagaccaat aggaggagaa ttactgatgg ctaacaatac
     8581 gattaataac tttgaaacac ttgataacca cgctcttgaa caagtcgtag gtggaagtgg
     8641 gtggatggat tatataaatg gtttcctaaa aggattcgga aggcaaagaa cgcttccaac
     8701 aaaagactat aacattcctc aagtttaggt atagaaaaaa ggctgttagg cctttttagt
     8761 tattgttaat tgttgtgtga atgagaaatt gttactctgt gtttctaagt ttacattgat
     8821 atagttatct aagatttctg tgacattagc aaggccaatg cctcgctctc gtcccttgtt
     8881 ggagacacct ctttcaaata tggttttagt ttctgtttgt tcttcactta tggtattgct
     8941 aatagataat agctgtgaac gatgatcttc ccaaaagcta atagtaattt tatggttttg
     9001 agtttgaatg gcaccttcaa tagcgttatc taaaaaaata gaagtgacga taatgaagtc
     9061 cagaatttcc atcccaatca agtggatggg ttctgggatg ctaatctgag cttcaatacc
     9121 ttcttcttct gcttgtaaaa cttttgcgga cagaaggctt ttcaaagtat tatcctgaat
     9181 attaacgagt ctagctaagt caaagtttct tgtatttaat cgtttatcgg attcttgaag
     9241 cacactatca tagacttctt tgacaatatc catatcgtct ttatctatcc ccaatcgtaa
     9301 tgtgactaag agattactat aatcgtgtct aaaactacga acagaattgt agagacattc
     9361 aatatgttta ttgtaggtgt agagattctc tagctggaga tttttctgga agtccaattg
     9421 tccttgaatc atttcacaaa tgtttctttc taaaaagaca atcataatga agaagaggac
     9481 aagtgaaata acaacacaga gttttcgaag ctccaaagtt gaagagtgag tagtgttttc
     9541 aagatacatg agggactgta acagtagggt gtacccaaac ataaaaaagt tagcaactat
     9601 aataatatgt tgaatcggag aatttgattt ctgcttttga agtatggtaa aactctcctt
     9661 aaataattta ataaagagaa atgatagaca aagaggtgcg atagatgaag ggatggatat
     9721 taatagagag cttttataat cggtgatact aatattaaaa aaaggaaaga taaaaaaagt
     9781 aatcagtctt aaactaaggt tgttgaggat atcagggaag agaccattga aaatctttat
     9841 ttttaatggt tttttagtct tagtggataa aaggaaggag agaagaagat agtagatatc
     9901 ctcaccccag aatttaatga taaaccaaga agagtggtta taaataaaat taaaggctaa
     9961 attaaaaata aggagtagga aaaaatacct cagacgaatc ttctgtccca ttaaataaag
    10021 gaaaagaata atttctaggc ctgcacttaa aagggtgaga aaaagtagcc ataacgttgt
    10081 taacatcctc tgcctctttc ctcaacaatc tgtgcaatct ttcctatctt catacgggat
    10141 actggtagaa cttgaccatt aattaaggta gcttcataat tggtcttgtt gacagagatg
    10201 atcatatctg tattgacgat ataggagcga tggcatgggt agagcttttt gtgtatcttt
    10261 tttaaatctg ctagatttgc tcggatatct attagggtat agatagtctg gaggtgaaca
    10321 tggtgtttga tatctgatgt agataggtat agaatttgat ccataggaag gtttattaat
    10381 tgagactctg ttttgtagag aaaaaactca tccgtggtag ttgcgttaat agggaagact
    10441 tgagcaatgg tttcccctat ctcttttcta aagctagctt catctaaggt tttatcgatg
    10501 tatttatagg ctgtaacgcc aaaagcttga ggcatgaact ctatatgtgt agtgacaaag
    10561 gcaatgatgg cataggggtt attttgacgt atgattttag caatatttag ccccttctta
    10621 tcttcacctt taatttcaat atcaagaaag aaaacctgat cgcttgtgtt ggaggtgata
    10681 gctgataaca actggtctgg tttgtcaaag gaatggacac aagatagatc ttttccgaag
    10741 gatttaagtt catgtgccac agcctcttcc aagcgaccca tctgaatatg attatcttct
    10801 aataggtaaa ttctcaaggt tgagtcctcc ctttcatgac gaatactgtt tattgaaaaa
    10861 attgtaacat aaagaaaacg gcttttcaat ttttttatta gtggaaaatg agattttttt
    10921 tttttctgaa ttttagaaac aatatacatt aggaattacc attcggaaca tatagccact
    10981 ttttgggacg ctagctctga tagagacact tgaatgctat actaaagatg tgattgagag
    11041 atcacacgat aaaaatttta ggaggtagtt gccatggcaa ctcaaacaat tgaaaacttt
    11101 aacaccctcg acctcgaaac acttgctagt gttgagggtg ggttgtcctg tgatgagggg
    11161 atgctggcag taggaggact tggtgctgta ggtggcccgt ggggagctgt cggtggggtg
    11221 ttagtaggtg cagccttata ctgtttctaa tttgtatggg aggaatttat gaataataaa
    11281 caacttgaaa gatttaaaaa actggataca aatgcattgt ctaatgtaag tggtcaaggc
    11341 tatggtgctc aatgtgttat tggtactgcc ggaatgacga ttgtcggtgc agctttcttt
    11401 ggcatcgcag gtgcaggaac tggatttgca ggcggtagca cagcattttg ttatggtaca
    11461 gctgaataat cttcatttga gataggtgat acaaatgaag aaatacctaa tcattttttc
    11521 gactattgcg atgatatatt tatatagcaa agtactattg tcatcaggaa atatctatca
    11581 acttttgtta gcatcaatag gattcttttt ctttttattt ggagtctata ggcagtatag
    11641 aaagaaatag ttaaagcttt ttcaataaga catggactga atcaaaaatg atattcagtc
    11701 ttttttttac tactcgggac atatagccac tttttgggac gctagctctg atagagacac
    11761 ttgaatgcta tactaaagat gtgattgaga gatcacacga taaaaatttt aggaggtagt
    11821 tgccatggca actcaaacaa ttgaaaactt taacaccctt gacctcgaaa cacttgctag
    11881 tgttgaagga ggtggatgta gttggagagg cgcaggtgga gcgactgttc aaggagctat
    11941 cggaggagcg tttggaggta atgtagtttt accagttgta ggctcagttc ctggttatct
    12001 agctggtggt gttctaggtg gtgcaggtgg tactgttgcc tatggagcaa cctgctggtg
    12061 gagctaatct atggtatatt ttattatagg ttttgttgtt gctttgttag gtaatatctt
    12121 tttcaaaaag gtcaataaaa ataaacataa aaaataatct tgaacatata cgggtatttt
    12181 cataacaatt tttaataatt tgtttataag atagtgttat tttctttgaa caaatagttt
    12241 atttttatgt agatggggag ttaactaatg attacagaac taacatataa cgaccttgaa
    12301 accatccaag gtggagtatc ttgtattatg cctagaacaa ataataaagc tggtggtagc
    12361 tacgacccct ttatagacgg tagggtatcg ccacctagat atcgaagtgg cgaagcctat
    12421 ccgatggtat atcttcctat ctgtgttctt atgtaggaag ttgaaatcaa ggttcttatt
    12481 cgataatgac tattaagatc actttatcat cttaaagtgg tcttttatat ttttttaccg
    12541 ttcgggacat atagccactt tttgggacgc tagctctgat agagacactt gaatgctata
    12601 ctaaagatgt gattgagaga tcacacgata aaaattttag gaggtagttg ccatggcaac
    12661 ccaaacaatg aacaattttg aaacactcga tctcgaggca cttgcaaacg ttgaaggtgg
    12721 tggatgtagc tggggaggtt ttgctaaaca aggagtagct acaggagttg gtaatggttt
    12781 acgactaggt atcaaaacac gtacttggca aggtgctgtc gcaggagcag ctggaggtgc
    12841 tatcgtaggt ggtgttggtt atggagcaac atgctggtgg tgatggatta tgtttgattt
    12901 gaaaagttat attttaggga tggtttccat ggctgttatg agttttttag ataagcctat
    12961 tatgtcattt cttgaaaaac acaaggctac caattccgtt aagaagaaat cctaactgag
    13021 atgtcttgtc aattgctggt ctgtgaatag catgtgaatt atgattgaaa atttcgatat
    13081 aagagaagag gtatttgtaa tcatgaccaa aaaacgccta gtgtctctaa tgatgtctat
    13141 gggcttcgtc cttgtttcct tacataactt tggagaaaaa ctgaattttg gacttcaatg
    13201 cctaaatctt atcgggttat gtttatttct ctttcttatg tgtacggtta tcaaggatat
    13261 aaggtcagac aagtagtgac atttatgtca ctactttttt atcggcttcc aatctataat
    13321 aaaattcata gattacgcac agaaccatta acttgctagg gctaacggtg cttctttata
    13381 gcttactttt taaaaagtgg gtacagtttc aaaagtaacc tttggtcact ttgaacgtaa
    13441 gatgcttgca aatgcttatt tttgatgttc ccgaagtaaa attattcttg ctaatgatag
    13501 cggagattat attatatttg attgcatatc tttgtaatag agaaaacaaa gatatgtata
    13561 ttcgcctatt taaagtatca gtactaatga cactactgta ttacatctcc agtagaattt
    13621 aatcgctaag ggcttacttg aaatcttaca gctgtataat aaaatacaga gaggaataga
    13681 gttaaatgta atagcttatt aggtttgcaa gactgactga ggttattcat agtttaggtg
    13741 ttttatcatg aagttaaaga atattagttc gagtgtatta cgatctttta gaaccatcac
    13801 tgctgcgttg gcagttttcc ttataagtat cagcctttct ctctacaaaa gcaagatctc
    13861 gccaggaact tggctagcag tcggagcact agctttcgga gtcatttttg ttaatggact
    13921 gctctaccgt atgcttaaga agcgtccaga ttcagtaaat ctgttaacaa tacggcagtc
    13981 cttcattgtc tttcttatca tcacatttct agtgcttagt gtagagtttt acacattact
    14041 aacattcagt gataccacag accgtatagt actagccgta ttaatgcttt tgttaatcct
    14101 ctgtgatttt ctatcttacc ttcaagtcaa aaaatatttt aaacaataaa cgcatttgct
    14161 tgattattct gtaagcaatc tagaagatat ttgcataaaa gtgttataat aagaaagtga
    14221 ttaagtaaat atgtgaaaat tagaggaaga tttccaatga ttgaaggatg ttctttagga
    14281 attaccattc gggacatata gccacttttt gtgacgctag ctctgataga gacacttgaa
    14341 tgctatacta aagatgtgat tgagagatca cacgataaaa attttaggag gtagttgcca
    14401 tggcaaccca aacaatgaac aattttgaaa cactcgatct cgaggcactt gctagtgttg
    14461 aaggaggacg agtcaattgg gaacgatggg gaatgtgtgg ggcctctgtc gccgtaggtg
    14521 cttcagaagg attctctgca gctgcaggtg gaacggcttt cttcattgga ccgtatgcaa
    14581 ttggaactgg tgcagtaggt gcagctattg gaggtggagt agccttactt ggctgttaag
    14641 gagaacaaca atgacacata gagtttcaaa aagggatata gtgctatttg tcattgccca
    14701 agtagttagc atatccttac tggtactttt ttttagtcaa ttacttcata acttatcatc
    14761 cgtattccaa ttggtctaca tcgtagcagc cctcttagtg gttgtggttg atatattgct
    14821 cattcgaaaa ataatgacaa gaagagaaga accaactgtg ttaaatcaat taaaagcttc
    14881 cctagcttgt ttcttgttac tgacacttag ttgccttcgt tttttgacaa cagatttcta
    14941 ttatcaaaaa gttatcgcta tatttgtagg ttttttttca ttattgggtt tcgtactatt
    15001 tttatggggc atcaagtata tcaaccataa tatagagaag taagtaattg acaaaataag
    15061 gagtataagc aatgtttaca aaattaactc ataacgacct tgaagtaatt caaggtggtg
    15121 ctgtttgtct tatgccaaat gtgaataaca aggagggtga cccccttaaa gacggttggg
    15181 tatcaccacc tagatatcga agcggtgaag cctatcccat ggtatattta cctgtctgtg
    15241 ctattatgta agaactttaa tttaaaggct cttatttgat aagaatataa aagtccccct
    15301 tattacccga accttctggt gaacagctcc ctgtcaagtg gacaatgaaa taataaaaga
    15361 ttaggcgacg gccttgttcc tcatttcaag aggggcaagg ccgtttttgc gctc
//
