LOCUS       gnlProkkaJBEAMKMJ_4    24458 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBEAMKMJ_4.
ACCESSION   gnlProkkaJBEAMKMJ_4
VERSION     gnlProkkaJBEAMKMJ_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:47:20
            Original ID  :: gnl|Prokka|JBEAMKMJ_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 28832
            Orig. end    :: 53290
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24458
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14458]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14458
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24458
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24458
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             386..1903
                     /locus_tag="ctg4_27"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFALFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESIAGLGEWERTGIQLLIVLAVIIPAGQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWAMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHHLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             1918..4530
                     /locus_tag="ctg4_28"
                     /transl_table=11
                     /translation="MGITSVLTKDNVNKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSH
                     IENQGGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERLKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLNERSKKTISIAPLIAAWIHWGGHTLEEWSQMTAIEQ
                     NEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGEKSALAQLAFCIDVR
                     SEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADEDV
                     FKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIRN
                     LREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICGH
                     GSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEYTVFAAA
                     EHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPKA
                     EANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLAN
                     IIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQSV
                     MESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGWVRLASIDPEGCWESW"
     CDS             4607..5137
                     /locus_tag="ctg4_29"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNELTQLETMKDKIQTLDYLFQNCK
                     PEFFGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVNHNDGKPSIVEVPDV
                     KTGQAIPDHCLSR"
     CDS             5091..5201
                     /locus_tag="ctg4_30"
                     /transl_table=11
                     /translation="MLKQVKPYLIIACHDEIQVQLLNAPIYGESSSKEIV"
     CDS             5198..5488
                     /locus_tag="ctg4_31"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECLKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVRKY"
     CDS             5545..5919
                     /locus_tag="ctg4_32"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             complement(6022..6195)
                     /locus_tag="ctg4_33"
                     /transl_table=11
                     /translation="MFSNIVQVTNHQHQIHVFKIDVKKHPLITTADVRSFDRNNTTVYY
                     ELTSLYVRLGYE"
     CDS             6403..6705
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_34"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             6832..8004
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 335.3; E-value: 6.3e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_35"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQF
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             8768..8938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_36"
                     /sec_met_domain="Antimicr18 (E-value: 7.2e-07, bitscore:
                     23.8, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNNIFDLDINKKMESTSEVSAQTWATIGKTIVQSVKKCRTFTC
                     GCSLGSCSNCN"
     CDS_motif       8768..8839
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MEKNNIFDLDINKKMESTSEVSAQ"
                     /locus_tag="ctg4_36_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8840..8938
                     /prepeptide="core"
                     /locus_tag="ctg4_36_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="14.10"
                     /molecular_weight="3235.8"
                     /monoisotopic_mass="3233.6"
                     /core_sequence="TWATIGKTIVQSVKKCRTFTCGCSLGSCSNCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKNNIFDLDINKKMESTSEVSAQ"
                     /leader_location="[8767:8839](+)"
                     /alternative_weights="3253.8"
                     /alternative_weights="3271.8"
                     /alternative_weights="3289.8"
                     /alternative_weights="3307.8"
     CDS             9026..10000
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 154.5; E-value: 9.1e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_37"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.6e-26, bitscore:
                     87.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMTTNALPNQFSWNSYKVTNGYRLYDLQVGSPLIKIAVIDSGYD
                     PNHSEITGNIDKKKSCSFVDYENFNEDLYGHGTAVISVIVGKNQVKGVAPGITIISYKV
                     LDRNGFGKIEWVIHAILKAIEDCVHIINLSHVFTMFGLGNKGAFNKLQQAIDKARKKGI
                     IIVGAAGNQGVLLDMKSTSLYPTIKGINYVTSTNKNNYTSSYANIGSIIRFAAPSGELD
                     ETNNVTDLIIVAHPTNFPKTKFEKAIGLPDFYTVTCGTSISAAMFSSLIALVLTEYLIC
                     KQIHLSEKEILNIIQKNSSRVKDQNSIFEINAYSVIKFIKGLL"
     CDS             10001..13111
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     768.8; E-value: 1.2e-232)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_38"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.7e-133,
                     bitscore: 439.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.4e-08,
                     bitscore: 29.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.3e-32, bitscore:
                     106.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKYLSSDLFMYRKPILDLSFYKECLAFDNEFNEEEYIAKISNL
                     LNTNPTIAEAIYFASEPLYNSFLNIEKLKKKKRKSVINSMLKFLIRMSTRPTPFGLFSG
                     IGVETFSGQDEYLTKDSEVIKNTRLDMCWIYFLIRKLESNLSILEQLTVENNSLVYNHG
                     DRIKLSYQSLLHSDDNDQSLEMLTLRKTAVMDYVYSQAEFGINYSTLRDSINKTYSVTD
                     DISNDFLNSLLKNEVIITNLRTSLVNSDPFENILNIISKMHNVEEELNYLVRLKKSIEE
                     YKKSSGELGISILKKIKKEMRVIGYEGDDFLRTDLYYVRNKKRYINNNQKDSIEKLAEI
                     LSLLGSVNSFQPLEAYRDEFIDKYGIFQEVPLLELIDEELGIGLPPEYHENRHKPSQPE
                     PSNEFHRIKNIISSWQAEVSLSKNHEIKLDDEKIKHLFNSEELNNIAVSQELELYFNIL
                     LDEHKENKLYLNPNCGSNSLFQTYGRFKYFLGESDKEYIKQFSHIEKDVIFAEVTYYPT
                     HGKTANIINAETCFDYEIAFSCNSSKDNKHSIALSDLYVGSTYNFIYLKSKKLDKIIIP
                     KLSHMFNYSMGPKVYRFLVDIGVQYQKQWSNIDSFFYDAPIKPRVIYNNIVLSPKKWNL
                     NKSIIPFECDSGEKFHYYIKDWKKRYKVPDFIYLIEFDNKLLLNLENISHIKIIYNEFK
                     KLSNNQSLHFLEAEKELFNNHNNEIEEYVFTLKSKLHQLELDSYMTNIQSEMPFKYIGD
                     NERLKFLGTEWIYVKLYGLGTRENEFIADELGSFIKKHLDKGTIKSSFFIRYSDPKQHL
                     RVRFKVEKNNIFDTVLPIIIKWLEEMRTKGFVNYYCFDPYNPEIERYGGEQSYKIAEDL
                     FFCDSLIVSEWIQINRSGNVNIDEVTFGVFNILQLLKLFNLNIEEQMTWLEINTKPQKY
                     ANKFRGKKSTLIELADLIYTNKKLDKYNKISSIIEIREKTAITYSKSIENNPDFLIKNI
                     IMSVIHMHCNRLYGINRDKENLVIGLAYHTIKNYNNALKYNNVLIPN"
     CDS             13136..14458
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     332.4; E-value: 6.1e-101)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_39"
                     /sec_met_domain="LANC_like (E-value: 2.5e-62, bitscore:
                     205.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKCKNQDFLTDILLDIANSIKDKSETEKIILGDQNNPEDIIEVV
                     SLAAGYPGICVFLGYMDKVFPEDGWDVVAHDYLTDLISLIQTNKTYSLSLFNGLAGVLV
                     ALETCSRGGTRYTTIINQVLTLILENYKHYLSEDLLKLKKEGVSASEYDVISGWTGVGR
                     TLLHFDQISNKGDISLKKALHDIAEYLLLVSSIDTLSNMPNWLISNENLPLDIEKKTYK
                     KGYFNSGMAHGISGVLAFLSILKKENYKIKNLELGIKNIQNWIFEKVKTHKGIYYIPNV
                     IENEVVRNEAFFNHRDAWCYGTPGVSRSIFLSGIALNDQRVKMKALELFKTFFLRDEKD
                     RKIISPTICHGYAGILMLTLRMYKDTNDRFLADKMHDILNEMLTFYSQLNFSKFNNYEL
                     ISGKIVEEKKVGLLEGSTGIALVLISFIFGQDSWDKIFLIS"
     CDS             14471..15061
                     /locus_tag="ctg4_40"
                     /transl_table=11
                     /translation="MIQAVLEITIKFLTELISFELPVYMYIWFAVLFIFSMIVENVQLA
                     IAKDSILNSILKRLGIKILSLLVVLIIGVLGSNFFAQVVEDAVNKESNLAYYILSTTIA
                     TALTIIEPIIETMKKFIKEQSNLAFANFTVSVICLTVTFQAVSSIFSDYFILATPYKVV
                     LIISSAIGIVYLVKFDQNNLEVNSESVHSNKND"
     CDS             15079..16836
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     251.8; E-value: 8.4e-77)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 316.8; E-value:
                     4.7e-96)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_41"
                     /transl_table=11
                     /translation="MGNNHLLLLLKLVKWPKKILVYILFSLLFTTILSLVIPILTKNTV
                     DQFTDGTVNWALTIMLAGLFLINILLSGLSFYYLAFLGENATYYIRDKMFSHILDLPLT
                     FFDKNESGQIVSRVIDDVELMNTFISDKIPNFASQLIVVAGSLILLFVLDWKITLLMLI
                     SVPISLAVMIPLGNKMYKISLEKQNNMAIFTARISSAFSGIRLTKSYTAEKEEYGKGNV
                     ILKRIFKLNLKDTKIQAYMMPIMSTVILMIILLLVGYGGIRLSEGTISPGTFVAIIFYL
                     VQFVTPLSSLSNFFTEYKKTLGATKRLYEIYSLKPEAENKQISSNAFNLGNGDLKFENI
                     SFQYNDPSSEVFNKLNLRFPKNKITAVVGPSGAGKSTLFNLIERLYEAQNGEIYYESTP
                     IKDIDLTVWRKKIGYVMQDTLMITGTIKENLTYGLSGSVSQETIIKYSKLANAHDFIME
                     LPDNYETFIGERGIKLSGGQKQRIAIARALIKNPEILLLDEATSNLDSESEILVQQSIN
                     RLVRDRTTIIIAHRLSTIRDADNIVFLENGVVTGSGNHLDLINNHEKYREFVNGQLLNN
                     TSVSASSLS"
     CDS             17038..18015
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_42"
                     /sec_met_domain="PF00561 (E-value: 4.9e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVCVSVFIYHHFQLNKEAALLKEKG
                     TLVEVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             18017..18688
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.8; E-value: 7.7e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_43"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGELLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             18685..19671
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 55.2; E-value: 1.1e-16)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_44"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKPADQDVIWMSNALWMERLFDNIFQNTLRHSKAKKMEVTIEHGDVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE"
     CDS             19730..19984
                     /locus_tag="ctg4_45"
                     /transl_table=11
                     /translation="MNIICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAAAR
                     AKEETTTVMAAVIVTNAGATAAVNPKKFLFRFWDKGFFM"
     CDS             complement(19977..20747)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.9;
                     E-value: 6.5e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_46"
                     /sec_met_domain="Pkinase (E-value: 3.8e-33, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKARKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIDEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20833..21690)
                     /locus_tag="ctg4_47"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAVGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     IAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21822..23006
                     /locus_tag="ctg4_48"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPAGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 taaaatatgt aggcctttag cattcttttc atatttaatt ttaaatattg ataggatgaa
       61 aaagtatcct aataaaaaag gaagagaaca tgagtcgatt tatttgataa tcaggactat
      121 attaaaggaa atgaaaacat agcataaaaa agtaaagacc aataataagg tagcacttca
      181 aaaaacttcg ctgaagttag ttgaagtgaa gccgacaatt ttcaggattc aatgatctaa
      241 cataatcatt gaaattttga agttgtcggc ttttttgttg gaaaaaaata gagataaata
      301 aaaattgaaa taaataatag acaaatatga tctgattgaa aggtcttttg aacaataatg
      361 agttttaaaa aagggagaat ttggaatgtt agtttcgctg agtttgtcat cattattaac
      421 attatttttt attatgctta tggcttctgg gattagtgga ctattgtttt tacatccgcg
      481 agtacccttg agttttgttc gcattcatat tgggatcttg gctttaccac ttttggtttc
      541 cttactgatt cttgccaata gtggtgtgag tggaaatgtt ggcccttggc acttagattc
      601 cttagcttgt ttaatgactt tctttgttct tgcaattgga ttcatcattc agcgtttttc
      661 tgtacgttac ttaatggggg atcgatctta tcgaaaatat tttgcgcttt ttactttcac
      721 aacaggtgct gcttctatga catggttaag tggtgatctc cgcttgatgg ttctattttg
      781 gggagcgact cttgttggat taaccttact tattaggtta aacagtgctt ggcaagtggc
      841 tagtgaagca gccaaaattt ctggccggtt atttttgtta agttggtttt ctttgttttt
      901 tgcgatgatg tggctttttc atgccacagg tcaatggcag ttatcattgg ttgtaacaaa
      961 tgaaagtata gctgggctgg gagaatggga gagaacaggg attcagctat tgattgtact
     1021 ggcggtgatc attcctgcag gtcaatggcc gttccaaaga tggttggttg agtctattgt
     1081 tgctccaacc ccagtttctg caattatgca tgcaggttta gtaaatgctg gaggaataat
     1141 actaactcga ttttcacctc tatttcatgg tggtatcgct tcgattatct tacttctgct
     1201 tgctggcatt tctgtattga ttggaactgg aattagttta gtccaggttg attataaacg
     1261 ccagttagta ggctccacga ttggacaaat ggggtttatg ctcattcagt gtgcattagg
     1321 cgcctatata gcagccatta ttcatcttat tttacatggt ttattcaaag ctacgttgtt
     1381 tctacaagct ggttcagcag tagggcgtca tgaagtatcg gctcgcacta atgaaagaac
     1441 atcctattta tgggccatgg ctggtcggat tttatcctta gttataggtg ttgctttttg
     1501 gctcactgct cctggagacg ggtatcactt aatcagtgcg ctgatcttag ggtggtcatt
     1561 gtccgtttct tggactcagc ttgtcgcttt tggagagggc cgaattggcc gaattgccgg
     1621 cttaactgtt ttaggaggag cagccctcgt atattttatc attcatcacc ttttctataa
     1681 gtggctgcat acaaccattt ttcaaagtgt tcaacctcca atgtcagctg tcatgattgt
     1741 cgtatgtctc ttactatttg gcagtgcttt aggtacgtgg gttgctcgtc atcgttcttc
     1801 cgtttttttc gcggtactct atctttggtt agttcgatta ggtgaagcaa aaccaaagtc
     1861 agtagagagt cacccagact accttaaaca atatatttca taaggagcta atctgagatg
     1921 ggcattacat ccgtattaac gaaagataat gtaaacaaga tagatacaga tattgatgtt
     1981 caagaaaggg atcttaacgt tttcattaca tctgccagcc gagtgattgc gccactttgg
     2041 cctatttcta catttgctgc acgtaatccg tggatgggac ttgaaaacca accttttgat
     2101 caggttgcaa gttggttgaa aaacactcgt gatgttgata tataccctag tgcgtctatg
     2161 atccgttcag caaagaataa aggtgagatt gatgaagatt ttgtggaaat ggggctgcag
     2221 cgttggcttg attcacattc ctatcacatt ccacgggacg tggcagagcg attttgtcat
     2281 gctgcattaa agttagatcc cctgccttcc gaccttttat catcacatga gctggagaaa
     2341 ttagtaggtg aatgtagtgg attggatcat atcgagaatg tgtttatgca gccactaagt
     2401 tcgcatatag agaatcaagg tggtgaaagg ctagtcaata tactagatca tcatgtcatt
     2461 aaatggagta aattatatct tgatgactct caagcaggct ggacaatgcc taatcgtgag
     2521 gaaggtttct atcgtgcttg gcagcatctc attcaatatg atccagcact tagtaaaaag
     2581 cagcgagaaa ggttaaaagg ttggccgaaa gaggcacatt tggctttaca ggaagcctta
     2641 ttcgcactag aaatcccaga gtcagaaatc cagacttatc ttgaaggtca tttactttca
     2701 ttacctggat gggcagggat gatgctttgg cgctcccagc aatcgagcca cgaacatgca
     2761 ctcctaacag aatacttagc ggttcgaata tccatggagt gggctcttat aaagccatac
     2821 ttacctttga atgaacgatc taagaaaaca atttcaattg ctccccttat agcagcttgg
     2881 attcattggg gtgggcatac attagaagaa tggtcacaga tgacggccat tgaacaaaac
     2941 gaatatttat catttgccta cagctttgat gagaaacttc gcaagaaact ttggttagaa
     3001 gcttgggaac aaacgtacac tgatcgatta agccagaaga tcatctcgaa acaacgtgaa
     3061 accggcggtg aaaaatctgc attagctcaa ttagcattct gcatcgatgt acgatcagaa
     3121 ccttttcgtc gtcaactaga aaaagaaggc ccgtttgaaa cgattggtat tgctggtttc
     3181 ttcggggtgc caattgcaac ttgtgaactt ggcagtaaac acagtcatgc ttccttgccg
     3241 atcatacaaa aaccgcaaaa taaaataaaa gagttcgcag atgaggatgt attcaaaaaa
     3301 tacaatcaac ggaagcaagc aattcattct ttaagccata cctttaaaac gatgaagcag
     3361 aatgcgcttt cgagcttact actgcctgag ctaagcggac cttggcttac tctgcaaatg
     3421 gcagcccgta gctttgtgcc aagaaaggcg ggtcgtttca ttcgtaatct ccgtgaggct
     3481 tggttacgca aacctgatac aaaactctcg cttcatcatg atgctacaga ggcagaaata
     3541 cctgtgggtt ttactgatga agaaaaagtg aactatgctc gccaagcatt aaaaatgatg
     3601 gggttaacag agaacatcgc accattggtc gtaatttgcg ggcatggcag tcaaagcact
     3661 aataatcctt attctgcagc ccttgattgt ggtgcctgcg gtggagcggc cggtggattc
     3721 aatgcaagag ttttagctgc tttatgtaat ctatcagagg tacgagaagc tcttttagct
     3781 gaaggaattc aaattcctga gtatacggtt tttgcagcag ctgaacataa tacaacagta
     3841 gatgaattac attggcttta tgtaccagag ctttccgaag ctgcacaaga agcatttgaa
     3901 caaattgaag ctgttatgcc gaaagtgaga catcatgtaa acgcagaacg tctagcccaa
     3961 ttaccgaatt tccaatcgaa gctaaaaaat ccgaaggctg aggcaaaccg atttgcggaa
     4021 gattggagtg agatacgtcc ggaatgggga ctggctcgta atgccgcttt tattatcggt
     4081 aaacgtgaac taactcagga ttgtgatttg gaaggcagag cctttctcca taattatgat
     4141 tggaagcagg atgaaagcgg tgaactccta gcaaatatta ttgcaggacc tggtactgta
     4201 gcccaatgga ttaatttaca atattacgca tcaacggtag cgcctcatta ttatggcagc
     4261 ggaaataaag caactcaaac cgttactgca ggtctcggcg ttatgcaggg gaatgcaagc
     4321 gacttgttag ccggactgcc ttggcaatcc gtcatggaat cagatcacga ggcctatcat
     4381 tctcctcttc gtttattgat actcatccaa gcacctagag aatatgtaga acggttatta
     4441 aatcatgact cagcatttct gcaaaaagtt caaaatggat gggtccgact ggctagtatt
     4501 gatccagaag gatgttggga aagctggtaa tgatgaatct aagcatttat caaatggatt
     4561 tgttacttaa tacaaaaatg ataaacataa ggaagaggtg tgctgtatga atgtaaacca
     4621 aaataaaaaa gtattatttt tgacggatat tgaaaacggt ttggagccta ttttacaaga
     4681 agcgactaac acttctgcag agaatatgtt gactatacaa agctatggtg ccggtatctc
     4741 acatccttat ggagaaatca tgaggtctgt tatttttgcg atttaccagg aagatgttga
     4801 ggagattttt gtagtgggaa caaaagataa gaagacttcc gcaggtaatg aactaactca
     4861 acttgaaaca atgaaagata aaatacaaac attggattat ctctttcaaa attgcaagcc
     4921 tgaatttttt ggtggtacgg tcgatgaatg gctaaatgaa aatagcagtg acaccattga
     4981 aaaaagtgtt gatatgattc gacatcatcc actagtgccg tcatatgtta aagttagagg
     5041 tttattcgtt aatcataatg atggaaaacc ctcaatcgtg gaggttcctg atgttaaaac
     5101 aggtcaagcc atacctgatc attgcttgtc acgatgaaat acaggttcaa cttctaaacg
     5161 cacctatata tggagaaagc agttctaagg agattgtatg agcgctaatt taactgattt
     5221 tgtcacgaaa acaatagagg acatgaactc gtttgatcgt gaaaatatgg aatgtttgaa
     5281 aaaactaatt agaaaagcaa ttgattttta tcatctaaaa tcttatgaag aagttgagga
     5341 aacccattca ggaaacgttc gatttttgca tgtccactct atgatggaag aaaatatgtt
     5401 atccaaaatg atagtggtca caagaaacgg taaaactgat ttggatattg aaggtgtata
     5461 tgaaggatat gttgtaagaa aatattaata gacgaaatca caaatagaat atgccaattt
     5521 ttttgctcag gagatgtatt agatatgaaa aagtctaagg gttctattga atcagagatc
     5581 agtaagtcca tcactcaatg ggagaaggat tatcttggac gggggtctgt atctgttaag
     5641 actgatatac tgcgggacat gatcatcgtc aatttaaaag ggattttaac accagccgaa
     5701 tatgtagttt gtggatcaaa agagggtatg ttatctatca aacaaactcg ttcggagtta
     5761 gtcgaatcag gtatagaagg ccttaaggat attatcttaa aaataaccgg agaaaaagtg
     5821 aaaagttttc atactgattt aagctcccgg acaggtgaac gagtgatggt atttaaatta
     5881 tgtaatgatc tagagaaaaa tttggaaaag atcttataat ctaaagaaaa taaatgtttt
     5941 gacggtatgg aatttgttgt gaattgaaca taaagaaatg ccgattcttt tgttttacaa
     6001 ttatggcatc attgataact tttattcata tcctaagcgg acataaagag atgtcaattc
     6061 atagtacact gttgtgttat tcctgtcgaa agatctaaca tccgctgttg ttatgagcgg
     6121 atgttttttt acatctattt taaatacatg aatttgatgc tggtgattag tcacttgaac
     6181 aatatttgaa aacatccttg tcacctgccg ggttccccca agtgttttgt gaaatgatta
     6241 tgagaccaat ttcgtaaagc ttgctgataa atttaagcgg tgaacaaaat tgatatgctg
     6301 tcttcagttt catttcacgg aattagtcag agataaacct ttaattaaat atatccaaaa
     6361 aaacggattg acatatcgaa atataacgat ataataatcg atatggaacc aattgaagta
     6421 ttcaaagcct tatcaaatga atcaaggctg caaattttac aatggctgaa ggagcccgat
     6481 cgtcattttg caccccatga agggattgat atgaacacaa tcggggtatg tgtcagtcaa
     6541 ataacagaca aattgaaaat gacgcaatcg acagcttctc aatatcttac catcctttta
     6601 agagccggct tgattaaggc ggagcgtatt ggaaagtaca catattacaa aagagatgaa
     6661 gaagccattg ggaaacttgc tgactttctt aaaacagaga tataaaaata aacatcaaaa
     6721 gatgtttatt tttacaccat acatatcgac atattacgat gtgtttattt tttataataa
     6781 catatcgata attcgtgata tgtttattaa taattaagga gtgaatgttt tatgtctaac
     6841 acttggaaaa tttatatttt agccattgtc agctttttag ttggaacctc agagtacatc
     6901 atttccggaa ttttggatca aattgctcat actctcggga tcactttagc tgccgcgggc
     6961 cagtttatta ccattttttc acttgtatat gctctttcta cacccgtact tatggcgttg
     7021 acagcaagta tggatagacg caaattgatg atgtatgccc taggtttgtt tgtgttcggt
     7081 aatgtcctgg cttttgtact gcctggttat ggatggttta ttgcagcgcg gatcattatg
     7141 gcgatgggag caggtgtggt tgttgtcacc gcattaacga ttgcggctaa gattgcatcg
     7201 gaagggaagc agggcagtgc catcgctacg gtcgtgatgg gatttaccgc ttctttaatc
     7261 attggtgttc cgcttggaag aatgatagca gtagcattag gctggaagtc tgtatttgga
     7321 gccattgctt tgttgggatt gatcgcaatg gtcgttattt tctttactct tccgcatact
     7381 gaaggggata agcctgtgcc tttgcttcaa cagcttgctc ttttcaaaaa acggaaagtg
     7441 gctatgggat tatcaatcac tttcttctgg ctcgggggat attctgttgc ttacacttat
     7501 ttgtcaccgt atctcttgaa catctcaggt ataaatggca agctgctcag cggtgttttg
     7561 cttatatttg gaattgccag tttggttgga tcgaagtttg ggggatatag caccgataaa
     7621 tggggagtgc cctttacact cgttggcggg atgacgttgc atatcgtcac actgattctg
     7681 ctgtcacttg ttactcattc ctatatcgga gtgttggtga ttctcatatt atggtcgttt
     7741 gccgcatggt ccaccggtcc gacacagcaa tttcacctgg ctacaataga accggaaatg
     7801 tcaggtgttt tgcttagcat gaatcagtca atgatgcaat tcgccatggc ggtcggcgca
     7861 ggtataggag gggtttttgt ggaaaacgta tcattggcct cgattacctg ggttggtgcg
     7921 ttaggggtta tgattgccat tattgcatca ttgctgattt tcaattcgca accgaaacaa
     7981 gcgctaaaag atatcaatca ataatttcga aagatctaac atccgctcgt tatacaagcg
     8041 ggtgtttttt tagcgttcaa agtcagtcca tgcatgagcc ctccaagggc cgacatcgtt
     8101 ctgtatgtgt cgaaggcgca ctgaagctga atgagatttc ttaaggcttt gccgcggcga
     8161 gctgaagtac agtacgattg ccttgatcga acactggaaa cacaagagaa cgtaaacctg
     8221 aacatccgcg taaacgtcaa ggaagttgcc acttggggag taaacacttg catcatctcg
     8281 ctgaaaggcc tagacaatgc ggatgacaga ttcgtattgc cggaagtaaa cacagcgctt
     8341 gctctgtttc cgttgtcgat tgcagctgat tgcttactaa tgctgccctg catctcggtt
     8401 gtgatgtcga taagcagcgt aaccttgtga agagtgttac tgtggagtaa gatttttaac
     8461 ccctttggaa tatagatcaa aaggtttttt aatacttata aactgaagga gatcaatttt
     8521 aaatcgtttt aaaactatta aaggaagttt agtaacgata acttaaacat ctggctaata
     8581 agattactga ggatacatca aaagtcgaat agtaatagta gagagtaaaa gtaaccgtaa
     8641 gaagaattat aacaattagt tagcaaataa ttaaaaatgt cccaaaaaaa gtattgacta
     8701 actttttttg ggatagtact attgaattgc aaccggttga aagtatcaaa aaaaggagga
     8761 aatggaaatg gagaagaata atatttttga cctagacatt aataaaaaga tggaatctac
     8821 tagtgaggtt tctgctcaaa cttgggctac aatcggaaaa actattgtgc agtctgtgaa
     8881 aaaatgtaga acatttactt gtggatgttc gctaggctct tgcagtaact gtaactaatt
     8941 aggggatgag cagagggagt taaaatacat actatattaa aactccctct tcttctaaag
     9001 acaaggagta aacaattcca taaatatgaa tatgactaca aatgctttac ctaaccaatt
     9061 ttcttggaac tcttataaag taacaaatgg atataggcta tatgatcttc aagttgggag
     9121 ccctttaatt aagatagctg taattgatag tgggtatgat cctaatcatt ccgagattac
     9181 tggaaatatt gataaaaaaa aatcttgttc attcgttgat tatgagaatt ttaatgaaga
     9241 tctatatggg cacggtacag ctgttattag tgtgattgta gggaaaaatc aagttaaagg
     9301 agtagctccc ggaattacaa ttattagtta taaagtccta gatagaaatg gttttgggaa
     9361 aatagaatgg gtaatacatg ctattttaaa agccattgaa gattgtgtcc acattataaa
     9421 tttaagtcat gtttttacta tgttcggatt gggaaataaa ggagcattca ataaacttca
     9481 gcaggccatt gataaagcca gaaagaaagg cataataatt gtaggggcag cagggaatca
     9541 aggagtttta ttagatatga agagcacaag tttataccct acaattaagg gaattaacta
     9601 tgtcacctca acaaataaaa ataattacac ctcatcttac gcaaatattg ggtcaattat
     9661 tcgatttgct gcaccatcag gggaacttga tgaaacaaat aatgttacag acttaataat
     9721 agttgcacat cccacaaatt ttccaaaaac aaagtttgaa aaagcaattg ggcttccgga
     9781 cttttataca gttacatgtg gaactagtat atcagcagct atgttttcga gtctaatagc
     9841 attagtattg actgaatatt tgatatgtaa gcaaattcac ctatcagaaa aagaaattct
     9901 taatataatc caaaaaaact cctcacgagt aaaagatcaa aattctattt tcgaaataaa
     9961 tgcttatagt gtaataaaat ttatcaaagg attgttataa atgaatacaa aatatttaag
    10021 ctcagacttg tttatgtata gaaagccgat attggactta tcgttttata aagagtgttt
    10081 agcttttgat aatgaattta acgaagagga atacatagcg aagataagta acttgttaaa
    10141 cactaatccc actatagcag aggccattta ttttgcaagt gaaccactat ataattcttt
    10201 tttaaatata gaaaaattaa aaaagaaaaa gcgcaagagt gttattaata gtatgctaaa
    10261 gtttttaata agaatgagta caagaccaac tccatttggc cttttttcag gtattggggt
    10321 tgaaacattt tcaggtcagg atgaatattt aactaaagat tctgaagtta taaaaaatac
    10381 tcgtttggat atgtgttgga tctatttctt aataagaaaa ttagagagta accttagtat
    10441 tctcgagcag ttaactgtgg aaaataactc actggtttat aatcacggtg atagaatcaa
    10501 attaagttat caaagtctat tacacagtga cgataatgat cagtcattag aaatgttaac
    10561 ccttagaaag acagcagtaa tggattatgt ctattcgcaa gcagaattcg gtatcaatta
    10621 ctctacgtta cgagatagta taaataaaac atatagtgtt actgatgaca tatcaaatga
    10681 ttttttaaat agtctattaa aaaatgaagt tattataact aacttaagaa catctcttgt
    10741 taattctgat ccttttgaaa atatattaaa cataattagt aaaatgcata atgtagagga
    10801 agaattgaat tatttagttc gattaaaaaa atcgattgaa gaatacaaaa aatcttctgg
    10861 ggaattaggt ataagtattt taaagaaaat caaaaaggaa atgcgagtaa taggatacga
    10921 aggggatgat ttccttagaa cagatttgta ttatgtgaga aataaaaaac gatatattaa
    10981 taataaccaa aaagatagta tagagaagct agctgagatt ctttctctat taggatcagt
    11041 aaactctttc caacctttag aagcctatag agatgagttc attgataaat atggtatttt
    11101 tcaagaggta cctctcctcg aactcataga tgaagaatta ggtattggtt taccacctga
    11161 atatcatgaa aacaggcata aaccatcaca accagaaccg agtaatgaat ttcataggat
    11221 aaaaaatatt atatcttctt ggcaagcgga ggtgagttta tccaaaaatc atgagattaa
    11281 attagatgat gaaaagatta aacatttatt taactcggaa gaattaaata acattgcggt
    11341 atcacaagaa ttagaacttt attttaatat tttacttgat gaacacaaag aaaataaact
    11401 ctatttaaat cctaactgtg gttctaattc tctttttcaa acatatggaa gattcaaata
    11461 ttttttgggt gaaagtgata aagagtacat aaaacaattc tcacatatag aaaaagatgt
    11521 tatttttgca gaggttacgt attatcctac ccatggaaaa actgctaaca ttataaatgc
    11581 tgaaacatgc tttgattatg agatagcttt tagctgtaat tcgtccaaag ataataagca
    11641 ctcaattgcg ttgtctgact tatacgttgg gtcaacatat aactttattt atcttaagtc
    11701 aaaaaagttg gataaaatca taataccaaa attaagtcat atgtttaatt attcaatggg
    11761 ccctaaagtt tatagatttc ttgttgatat tggtgttcag tatcaaaaac aatggtctaa
    11821 tatagatagt ttcttttatg atgctccaat taaaccgagg gttatatata ataatattgt
    11881 attatcacct aaaaagtgga acttgaataa aagtattatt ccatttgaat gtgactctgg
    11941 agaaaaattc cattactata taaaagattg gaagaagaga tataaggtac ctgattttat
    12001 atatttaata gaatttgata ataaacttct gctgaactta gaaaatatct cacacattaa
    12061 aattatctat aatgaattta agaagctttc gaataatcaa tcactacatt ttttagaagc
    12121 agagaaagag ttgtttaata atcataacaa tgaaatagaa gaatacgttt ttactttaaa
    12181 gtcaaagtta catcaattag aacttgattc ttatatgaca aatattcaga gtgaaatgcc
    12241 ttttaaatat attggtgaca atgaaaggct taaattctta ggtacagaat ggatttatgt
    12301 gaaattatat ggattaggca ctagagaaaa tgaatttata gctgatgaac ttggctcgtt
    12361 tataaaaaaa catttagata aaggtactat taagtctagc tttttcatta gatatagtga
    12421 ccctaagcag catttacgtg ttagatttaa agttgaaaag aataacattt tcgatactgt
    12481 actcccgatt ataataaaat ggttagaaga aatgagaaca aagggttttg ttaattatta
    12541 ttgtttcgat ccatacaacc ctgaaataga aagatacgga ggggaacaat catataagat
    12601 tgcagaagat ttattttttt gtgactcatt gattgtttct gagtggatac aaattaacag
    12661 atctggaaat gttaatattg atgaagtgac ctttggagtt tttaatattc ttcaactatt
    12721 aaaattattt aatttaaata ttgaagagca aatgacatgg ttagaaatta atacaaaacc
    12781 gcagaaatac gctaataaat tcagagggaa aaaaagtact ttaattgagc tggcagactt
    12841 aatctatact aataagaaac ttgataaata taataaaatc tcaagtatta tagagatacg
    12901 agaaaaaact gcaatcacct attctaagag catagaaaat aatccagatt tcttaataaa
    12961 aaatattata atgagtgtaa tacacatgca ttgtaacaga ttatatggaa taaacaggga
    13021 caaagaaaac ttagttattg ggttagcata tcataccatt aaaaattata ataatgctct
    13081 aaagtataat aatgttttaa tccctaacta aattttaatt gaaaggaaag aattaatgca
    13141 gaaatgcaag aatcaagatt ttttaaccga tatcctttta gatatagcta attcaattaa
    13201 agataagtca gaaaccgaaa aaataatact tggtgatcaa aataatcctg aagatataat
    13261 tgaagtagta tcattggcag caggatatcc aggaatttgt gtgtttttag gttatatgga
    13321 taaagttttc cctgaagatg gatgggatgt tgtggcacac gactatttaa cagatttaat
    13381 ttccttaatt cagactaata aaacatactc actatcccta tttaatgggt tggcaggtgt
    13441 tttagtggct cttgaaactt gctctagagg cggaacaaga tatactacaa taataaatca
    13501 agtgctaacc ctaattttag aaaactataa acattatttg tctgaggact tgttgaagct
    13561 aaagaaagag ggagtgtccg cttctgaata tgatgttata agtggttgga caggtgttgg
    13621 aagaacccta ttgcattttg atcaaatatc aaataaagga gatatttcat taaaaaaagc
    13681 attgcatgat atagcagaat atttactgtt agttagcagt attgatactc taagtaatat
    13741 gccaaattgg cttatatcca atgaaaacct tcctttagat atcgagaaaa aaacttataa
    13801 aaaaggatat tttaattctg gcatggcgca tggaatttct ggagttttag catttttatc
    13861 gattctgaaa aaagaaaact ataaaataaa gaatttagaa ttaggtatta aaaacattca
    13921 aaattggata ttcgaaaagg taaaaacaca caaaggaatt tattatatac ctaatgtaat
    13981 tgaaaatgaa gttgttagaa atgaggcttt ttttaaccac agagatgcct ggtgctatgg
    14041 tacaccaggt gtgtcaaggt caatcttttt atcaggtata gctttgaacg atcaaagagt
    14101 taaaatgaaa gccctagaac tgtttaagac atttttttta cgtgatgaga aagatagaaa
    14161 aattatatcc cccacaattt gtcatggata tgccggcata ttaatgttga ctctaagaat
    14221 gtataaagat actaatgacc gatttctagc tgataaaatg catgatatac ttaatgaaat
    14281 gttaactttt tactctcaat taaacttttc caaattcaat aattatgaat taataagtgg
    14341 gaaaattgta gaagagaaaa aagtgggttt gttagaagga agtacgggaa ttgccttagt
    14401 tttaatttct ttcatttttg gtcaagattc gtgggacaag atatttctga taagttaaag
    14461 ggggataaaa ttgatacaag cagtactaga aatcactatt aaatttctaa cggaattaat
    14521 ctcttttgaa ttgccagtat atatgtatat ttggttcgca gttcttttca tattttcaat
    14581 gatagtcgaa aatgtacaat tggcaatagc taaggatagt atattaaatt ctattttaaa
    14641 aagattagga ataaaaattt taagtctatt ggtggtctta attattgggg ttttaggatc
    14701 aaactttttt gctcaggttg ttgaagacgc agtcaataaa gaatctaact tagcttatta
    14761 tattctgtct actacaatag ctacagcatt gaccataatc gaaccaataa ttgagacgat
    14821 gaaaaagttt ataaaagaac aatcaaatct tgcttttgca aattttacag tcagtgttat
    14881 ttgtcttact gtaacgtttc aagcagtctc aagcatcttt agtgattatt ttattttggc
    14941 caccccttat aaagtggtgt taataatttc atcagcaatt ggtattgtat atttggtgaa
    15001 attcgatcaa aataatttag aagttaatag cgaaagtgtt cattcaaata aaaatgatta
    15061 atctaagagg ttatacatat gggcaataac catttactat tactgcttaa acttgttaaa
    15121 tggccaaaaa aaatattagt atatatttta ttttcattac tatttacaac tatactatcc
    15181 ttggtaatac caatattgac taaaaatact gttgatcaat tcactgatgg aacagtaaat
    15241 tgggccttaa caataatgtt agcaggttta tttctcataa atattttatt aagtggatta
    15301 tctttttatt atctagcatt tttaggtgag aatgcgactt actatatacg agataaaatg
    15361 ttttctcata ttttagattt acctctaacg ttttttgata aaaatgaatc tggtcaaatt
    15421 gtaagtagag ttatagatga tgttgagtta atgaatactt ttatttctga caagatacca
    15481 aactttgctt ctcaattgat agtagttgcc ggatcattaa ttcttctgtt tgtgctggat
    15541 tggaaaataa cattacttat gttgatttct gttcctattt cattagctgt tatgattcca
    15601 ttggggaata agatgtataa aatttcttta gaaaaacaaa ataatatggc aatatttact
    15661 gcaagaataa gtagtgcatt ttcaggaatt agacttacaa aaagttatac tgcagaaaaa
    15721 gaagagtatg ggaaaggtaa tgtcatttta aaaagaattt ttaagcttaa tctaaaagat
    15781 actaagatac aagcttatat gatgcctatt atgtctactg ttatactaat gataatatta
    15841 ttgttagtgg ggtatggggg gataaggtta tcggaaggaa ctatttcacc aggtaccttt
    15901 gttgcaataa ttttttactt agttcaattt gttacacctc tttcctctct gtctaacttt
    15961 tttactgaat ataaaaaaac actaggtgca acaaaaagat tatatgaaat atattcacta
    16021 aaacccgagg ccgaaaataa acaaattagc agtaatgcat ttaacttggg aaatggggat
    16081 ctgaaatttg agaacatttc gtttcagtat aacgatcctt cttctgaagt atttaacaaa
    16141 ctgaatttgc gttttccaaa aaataagata acagctgttg taggtccttc tggagctgga
    16201 aaatcaactt tatttaattt aatagaacgt ttgtatgaag ctcaaaatgg tgaaatctat
    16261 tatgaatcaa ctcctataaa agacattgat ttgactgttt ggagaaaaaa aattggttat
    16321 gtaatgcaag atactttgat gatcaccggc acgataaaag agaacctgac gtacggttta
    16381 tcaggctctg tatctcaaga aactataatt aaatattcta aattagccaa tgcccatgat
    16441 tttattatgg agcttccaga taattatgaa acctttattg gagaaagggg tataaaatta
    16501 tcaggtggtc aaaaacaaag aattgcaata gcaagagcat taattaaaaa ccctgaaata
    16561 cttttattag atgaggcaac ttcaaattta gacagtgaaa gtgaaatatt ggtacaacaa
    16621 tctataaata gactagttcg tgatagaacc actattatta tagctcatag attgtcaacg
    16681 attagagatg cagataacat tgtattttta gaaaatggag tggttacagg aagcggtaat
    16741 catttggacc taataaataa ccatgaaaaa taccgagagt ttgttaacgg tcaattgcta
    16801 aataacactt cagtaagcgc gagttctcta agttaattgt gcataaataa tgagaccact
    16861 tgggtacact ttttatcggt tctataacca taaaaagcag ctgaactttt agttcagctg
    16921 ctttttgatt gaatcttgcg actagaaagt caaatgtgaa aataaaactg ttccaaagtt
    16981 aatcagaaat ttattttcat attgtatcct ttcagtatca cgtgaaagga gcatcatatg
    17041 aaaacattat ggaaagtcct caaaattgtt tttgtcagct tggctgcttt ggttttgctt
    17101 gtatgcgtct cggtatttat ttatcaccat ttccagctaa ataaggaggc ggcactcctt
    17161 aaagaaaaag gcacattagt cgaagttgat ggtaaaaaga tgaatgtgta tcaagaggga
    17221 agcgggaagg atacgtttgt gtttatgtcc ggttcgggga ttgctgcgcc tgcttatgaa
    17281 atgaaggggc tgtacagcaa gttttcaaaa gaaaataaga ttgctgttgt agatcgggca
    17341 ggttatggat acagtgaagt gtctcacgat gacagagata ttgatacggt attggaacag
    17401 acgaggaaag cgcttatgaa aagcggaaat aagcctcctt atattttaat gcctcattcg
    17461 atatccggga ttgaagcgat gtattgggca cagaaatatc ctaaggaaat caaggccatt
    17521 attgcgatgg atattggatt gccccagcag tacgtcacgt ataaattgag cggagttgac
    17581 agattgaaag tgagagggtt ccacctgtta acctcgattg gttttcatcg gtttatgcct
    17641 tccgctgtat ataatcctga ggtgattcgg cagtcgtttt taactgatga agaaaaagaa
    17701 atctataaag ccattaactt taagcaattt tttaatgcag atatggagca tgagctttta
    17761 cagtcttacc aaaacggcag caaatctgtg aatctgccgg caccaaagga aactcccgtc
    17821 ttgattttag atgcggtctc tgaccaaaat agacattcaa agtatgctat acaaaaccga
    17881 aaagactatg aagcgtttgc ggctcaattc aatactgccg atataaagga actgagggga
    17941 acacacagta tttatttata tcagcctgat caaatatata aactgtccat ggagtttatg
    18001 agaaaggttc gctaggatga agggatatca tattttaatc gtggaagacg atgtgatgat
    18061 tggtgaattg ctgcaaaaga ttttgcagcg tgagggatat cgtgtgatat ggaaaacaga
    18121 tggagcggat gtgctttcgg tgattcagaa ggtggatttg gtcattatgg atgtgatgct
    18181 gccgggtgaa gacgggtatc aaatgtctgc aaaaatcaaa gagctggggc tgggcattcc
    18241 ggtaattttt ctttcggccc gtaatgatat ggacagcaag cttcaaggtt tacagatcgg
    18301 cgaggattat atggtaaagc cctttgatcc gagagagctg ctattaagaa tgcggaatat
    18361 gcttgagcat cattatggca cctttacgca aatcaaacat ttgtatattg atgcggtaac
    18421 gaaaaaagtg ttcaatgaaa gcctgcatga tgaggtattg tttactgcga ttgagcggaa
    18481 aattttcttt tatttatatg aaaatagaga cagtatcctg acaaaggaac atttctttga
    18541 atatctatgg cagctcgaag atagaaaccc gaatattgtc aatgtgcata ttaaaaaaat
    18601 cagagctaaa atcaatgatc aagcgggtga gatgattgaa aatatatatg gagaagggta
    18661 tcggctgaat accgttgtga agaaatgaag ctcaagacaa aatatcagtt gttattgttt
    18721 acggctgtca ttagtgttcc gatgctgttg ctggcggtca gtgttttgat gtctgttatt
    18781 tatgacagca tgtttaaacc gatgaatcat ggtatgccct ttcacaggtc gtttgcgtac
    18841 ccggcaatga tcgttgtatt tttgatatcg ctcttattgt tagctttttt attttcaaag
    18901 tcgattcatt ctctgttgca taaaatcaat ctattaaatc aaaccattcg gcatttggcg
    18961 agtgatcaaa gggtgcccga taaaattgaa gtgaagcgtg ctgatgaaat cggggaactg
    19021 atcaagtcgg tcaatttgtt aattgaacgg acgacatatc gtgaactgga gctgagacag
    19081 caagaggaaa tcaaaaagga gcttttgcaa aaactgcggc atgacattaa tacaccttta
    19141 acggctctca ggctgcagtt attttatttg gaagaccaat gtcatggtca ggctgtattc
    19201 gaatcattgt atcagcaaat cgaatatatc tcggaattaa ccaatgaatt caatctatat
    19261 tccgctgaga cgctggaaag ctcttatatt gtaaatgaag aagtgcgtct aaacgagcta
    19321 ttagaaacag cggtgaaaaa gtgggattat ttatacagta tgagtgggat tgagctgcac
    19381 tataagccgg cagatcaaga tgtgatatgg atgagcaacg cgttatggat ggaaaggctg
    19441 tttgataata tttttcaaaa tacgttaagg cattcaaaag ctaaaaagat ggaagtcacg
    19501 attgaacatg gcgatgtttt tattcgtgat gacggtattg gatttgatcg gaatgagagc
    19561 agtgagggac ttgggttaaa gattattgag gatacatgca ggctgcttgc gattacttat
    19621 gagctgcata caaatgataa cggaacgggg ttcttgtttt caaaagagtg accccgctga
    19681 tgtttttctt tctcctataa aatttatata atagggagaa agaaatgggg tgaacatcat
    19741 atgtttaaaa aaatcatcaa aacgattaag tacctctcaa gcagttctag tgaccgatat
    19801 cgcagacacc ggcattacag cagcagccgg cgcagacatt atcgcagcta cagcagcagc
    19861 ccgggcaaaa gaagagacta cgaccgttat ggcggcagtc atcgttacaa acgccggagc
    19921 tacagcagca gttaatccaa aaaagttctt gttccgcttt tgggacaagg gtttttttat
    19981 gtgaccgatt gaatggcccg gtttagatcc tcgcgaatgg aagcggtgtg ctgatactcc
    20041 tcatcaatgc ccaataatct tttcagcagc agggttactt cctttgtcag tgttaattcc
    20101 tccagccaag tgccgttttt cttctttttt cctttatatt gagagtacag caggaataac
    20161 agcgtttctc cgagatcgaa gaagtcatcc tgttttcgtg cctttatttc ctccatttct
    20221 tcaggagtca attgtttggc aaggccgaaa tcgatgaggc agagcctgcc gtcattgatg
    20281 atgatattag gcgttctgat gtcgctgtgg aagataaggc gatcatgcag gtattctata
    20341 atctcaagca gctgcgaaat cagttgtaat gccataagct ctgtgaacgg ctgttttcga
    20401 aaaaataata attcttctat attctctccc tcaatgaact gcatgacata ataagcctgt
    20461 ccgtctatga tgaactcatc tatgaagccc ggaatttgcg ggtggtgaat gctattgagc
    20521 agttttattt cctgttggaa tcggactttc tctttttcct ttttcgcttt tgtcggccga
    20581 agctgcttta agacataagg tgtttgagtt aggatatctg tgcacaaata aaccaaaccg
    20641 tagcctccca taccgaggca ctcttcgatt ttgtattgat gatttaagat aacgccgttc
    20701 tttagagggc ggtcaaatag cagttttttt agaagcttta atgccatgtc tgcacttccc
    20761 ttggttgtac tgactatagt ttaccttcta gactgagaat aaaaaagagc cggataaccg
    20821 gctcggtata agttaaaact gctttgtcac gtcgtattca taatctattt ttgcttttac
    20881 gttgctcatc gtcgatctgg ctgtcgctaa tgtattatat ttaaaactcc atacctttgc
    20941 cacactgagt tgatctgaca aagagatatc ataagaccct gaagtcgagc tgtttacaag
    21001 agcacggcgc cattcgttgt tttcgctcgt catgatcagg tggcgtgtat ttccctggct
    21061 tggtgtttga gtggcggttg tctgaactct ggttacaatg gcatcacgcg gtatcccaga
    21121 ttggtttgtt aaatcaacct tgatcacgct ggagtcagaa cctgaggggc taaggcttgt
    21181 atttccttta ttttcagcaa tgccgctgaa ttggaatgtt ccgctgcctg atttgattcg
    21241 gtcttcaatt gaaagtgtaa aatacatgtt tccggtatag gtgcctcgtg acactttcac
    21301 ataaaaggta tccgtcgtgt tttgggcgtc tgcatttgca taaataaaag aagaaaacgt
    21361 attagggtta atgacttctg tcccttgaga aacaggtatt ctattcttat cataaatttc
    21421 aattttcatc cctgtatacg cgctctggta tgtactcctc acgtatactt tttctccctt
    21481 attagccgta aaagtgaaat aggcttcatc ttgaccagct tccagtattg ttgtatcgat
    21541 atttttatat ttccaataac cgatcggcat tgcggtatca aatgaattgt ttcctgtgat
    21601 agcagtgact ccgacagctg atgccgaata cgtaaaggtg aataagacag acagcataac
    21661 agcgaatgga ataagccatt ttttcaccat gcaaacaacc tccttttatt tccatcatac
    21721 ataataacga tttaggtgta aataaatgtt ttttgaggtt aatatataca ttatctttgc
    21781 cgataaaaaa gaataagaga gaatactcgg gagggaattc aatgcgtctg aatcggcaat
    21841 ttatccgcac tcagctgatg gcacagaaca tattgagcaa gaatgcgcct gccaaacggg
    21901 agaatgcgac tgaaaatcca gcggcagttc tggaaaaggc atacagcagg cttaagtcac
    21961 aatcttcaac tgggggaatc aatcagttca attattctaa aaccagcgtg tcgggaaaca
    22021 gcggggcgtt cagcaaagtg tatcaatcag cgaatgatcg aacagtgaca gacacagggg
    22081 aagaaacagt gattcaatcc caaaacccct atgaatctga gagtgatatc agaatcaaaa
    22141 tactagatga aaaatacagc aggatgaatg cgattaataa aacaaagtct gatccattag
    22201 gctatattaa ggataagtac caaaattcaa agtctcctta tttcagaagt gatctgtcag
    22261 ctgcagaaag acaggccgct tacgataatg aaacagaatg gttattcaaa gggaaggcgc
    22321 aaaactataa ccttcaggat gctgtgtttc ggaatgtcac atttcatggg gaagtggaag
    22381 ctgagaatga aaaggtgtat cagcggggac aggttaacca gcagctgcaa gtactgttga
    22441 atcgaaacca tattcatatt ccagagggga cagagctgac gtttacaatc acaccgattg
    22501 actatcaggt gcgggtaagc gggacagacg atcaggatct gatcaagcaa attgagcaag
    22561 tgctgcaatc tggagacaac agcaaagaac tatttttgca catcatgaaa agccaaagca
    22621 gtgattcagc acaattttcc gaagaggcct atcaaaagta tcaggctgct cgtgagatgt
    22681 atgaagttac aggctaccat ttgaaggatt tagaagtgat tgatgggcgg tacgtcacgc
    22741 ctgcgggacg tgacttaatg gatgtatata aggaagagct tgaaaaagat ccagtgcaga
    22801 aacaaacggc ttcttatgct atatcttact atcgttcaga gctcagtaaa atcgcggaag
    22861 ccgggtataa tgccattccg gatttcatcc tatcaattga ttacagcaat ggatctctga
    22921 gagatgtggg acaaagcaag agctatggga ccggagatac cgggtggctt gaagcattaa
    22981 agcgtcaaac gggtgtgaat tattaggtaa gctgttcatg taggacagct tattttttat
    23041 gagaatctaa ggggtgaatt aatcccaata ttcaaataat tttattattt ttatataaaa
    23101 gattttaaaa gaagtgaacg attcaaaact ctaaacaaag gtgtttgcct gaaaaaaaca
    23161 attgtatttt ccagagaaat ttattatgat gaaataagta atttaggaga ttatataaca
    23221 attttaagtt tgaattttct gattgttatc actgattcat gtgaaggcaa gcaggtctgc
    23281 tgttttctca tttatgagta ttttgttagg aggaggaaga ggagtggcaa ataaagaatt
    23341 aaagaggggc ctgggcgcgc gccatattca gatgatcgcc ttgggcggta caatcggtgt
    23401 tggcttgttt atgggttctg ccagcacgat ttcatggact ggtccatctg tccttctggc
    23461 ttatgcaata tgcggaattt ttatcttttt tattatgcgt gcgatgggtg aaatgctgta
    23521 tgtcgagccg agcacaggtt cttttgcgac gttcggccat caatatattc atccgatggc
    23581 aggttatata acagcatgga gcaactggtt ccagtggatt atcgtcggca tgtcagaaat
    23641 tatcgctgtc ggttcttata tgaagtattg gttcccggat ttgcctgctt ggatacctgg
    23701 tatcgtggca atggtgattc ttggtgcggc gaatttaatt tctgttaagt cgtttggcga
    23761 atttgagttt tggtttgcga tgattaaaat cgtgacgatt atcttgatga ttattgcggg
    23821 aatcggaatt attttcttcg gttttggcaa tggcggagat gcgatcggtt tgtcgaacct
    23881 gtggtctcac gggggcttct ttgcaggagg tttctcaggt ttcttctttg cactgtctct
    23941 tgtcattgca gcctatcaag gagttgagct gatcgggatt acagcgggtg aagcgaagga
    24001 cccgcaaaac acgctaagaa atgcgattca aagtattatc tggcgtattt tgattttcta
    24061 cattggcgct atttttgtga tcgtgacggt gtatccttgg gatgagctca actcactcgg
    24121 aagtccgttt gtgtctacgt tctcgaaaat tggaattacg gcagcggccg gcattattaa
    24181 ctttgtcgtg attactgcgg caatgtccgg ctgtaacagc ggtattttca gcgcgggccg
    24241 catgctgtat acactgggtg tcaatggaca agcaccgaaa ttctttaaga agatttcacg
    24301 caatggtgtg ccgctgtatg gcacaattgc ggtgctgatc ggtttggctg tcggcgttgt
    24361 actgaactat atcgcgccgc cgaagatctt tgtctatgta tacagcgcaa gcgtgctccc
    24421 agggatgatt ccttggttta tcattttgat cagccata
//
