LOCUS       c00119_gnlPro..        14236 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBOAHMLO_119.
ACCESSION   c00119_gnlPro..
VERSION     c00119_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:29:10
            Original ID  :: gnl|Prokka|CBOAHMLO_119
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14236
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..4236
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_1"
                     /sec_met_domain="HGD-D (E-value: 9.9e-64, bitscore: 207.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.5e-37, bitscore:
                     118.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KHALGIDIGSTTVKVTVINESHDILFSDYKRHFANIKGTLQTLLS
                     EAREKLGNLIIHPTVTGSGGMAISEYLHIPFCQEVVCVANALQDYEPKTDVAIELGGED
                     AKIIYFNNGIEQRMNGVCAGGTGSFIDQMASLLQTDATGLNEYARDYDTLYPIAARCGV
                     FAKSDIQPLINEGATKENLAASIFQAVVNQTISGLACGKPIKGYVAFLGGPLHFMPELK
                     NAFIRTLNLDEEHIIDPPYSHLFAAKGAALNAKEECSFTLDDLLKEFESDIQLAVEVER
                     MEPLFKDEKEYDEFIEEHNQFKVKKADLATYSGKCYLGIDAGSTTTKLALVGEDGSLLY
                     RFYDNNNGSPLNTTIRAMKELKELLPPAAKISGSCSTGYGEALIKAALQLDHGEVETMA
                     HYYAAAFFEPDVDCILDIGGQDMKCIKIRNHAVDNVLLNEACSSGCGSFIETFAKSLNY
                     SVADFAKVALFAPSPIDLGSRCTVFMNSKVKQAQKEGASVGDISAGLAYSVIRNALLKV
                     IKLTDPKQLGKKIVVQGGTFYNDAVLRSFERISGCHAVRPDIAGIMGAFGAALIARERE
                     EETGDTQMLSIDEIINLEYSTSMSRCQGCNNHCILTINKFNNDRQFISGNRCERGLGLE
                     KNHEHVPNLYEYKYKRIFGYKALKPDKAKRGVIGIPRVLNMYENYPFWYTFFTNLSFRV
                     LLSPKSSRKIYELGIESIPSESECYPAKIAHGHVMWLLKKGINTIFYPCVPYEEDQMEG
                     ANNHYNCPIVTSYAENIKNNMEELRDPNVLFMNPFLALDNADALKVRLYDELSKHFDVT
                     KEEIDHAVDEAYKEAAQVRKDVQAKGEETLAYLAETGKMGIVLCGRPYHIDPEINHGIP
                     ELINSFGIAVLSEDSICHLGHVERPLIVSDQWMYHSRLYAAANYAKKNKQLEVIQLNSF
                     GCGLDAVTTDQVNDIMTNSGRIYTVLKIDEVNNLGAARIRIRSLIAAVKIRNRKHIEPH
                     PVPANIEKVEFTKEMKKDYTILIPQMSPIHFDLLTPAFRHCGYNVEILPEMGKQAVDTG
                     LKYVNNDACYPSLIVVGQIMTALTSGKYDLNKTAVIISQTGGGCRATNYIGFIRRALAK
                     NGYGQIPVISLSVQGIEKNEGFKFTPSLLVRALQGVIYGDLFMRVLYRVRPYEKVKGSA
                     NHLHEVWKKRCIKSLEKARYGEFKKNIRGIIRDFDRLPITDEKKPRVGIVGEILVKFLP
                     DANNHLVELLEEEGAEAVMPDLLDFMFYSFYNSNFKAEYLGKSTKAAKLCNMAISALEA
                     YRGFLRKELERSDRFTAPPHIEELAEYAKPIVSLGNQTGEGWFLTGEMVELIKQGAPNI
                     VCTQPFACLPNHVVGKGVIKELRRKYPESNIVAIDYDPGASEVNQVNRIKLMLATAEKK
                     LKSDLPQAR"
     protocluster    1..14236
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4236](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4236
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14236
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14236
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(4866..5915)
                     /locus_tag="ctg119_2"
                     /transl_table=11
                     /translation="MVTKTDYYDVLGINKNADEKTIKKAYRKLAKKYHPDINPGDSNAE
                     AKFKEVTEAYEVLSDPEKKKLYDRFGHAAFDGTGNAQSGPYGNDGGFGGFSDFGGSGGF
                     HGGTYRSNNGNGYQEFHFEGGDMGDIFENFFGGGFKKSGFRGGFSQNGNFNNGFHGNSR
                     QNGGFGNRQSYQTKGSDVHADIKVSFDAAAFGKKETIHLKDENGKVQALEVNIPAGIET
                     GQSIRLKGKGTPGYNGGTAGDLFLKVTVSEKPGFKRDGQDIFNTVTIPFITAVLGGDVT
                     VPTIYGNVRCSIKPGTQSGSKLRLRGKGIVSMKNSSVHGDQYTTIEVQVPKNLSPKAKQ
                     KLREFAAEL"
     CDS             6126..6992
                     /locus_tag="ctg119_3"
                     /transl_table=11
                     /translation="MKKVTSLLMALILSVTILMGSIPMNASAATTEVPVGWYQQGKKVY
                     YYENGKKVTGWHTLKSYYDKKKYKFYFNKNGVLVTDLFTLNYKKWIKEDITIVVNTKTH
                     NATLYAKDKQTGKYNIPLKTMVCSTSRKAKGTKAYSGCRLEKTSAVRWFIYKKSRPYHY
                     YQWGVKVKHGNFYFHSARYTTTNNRKLEVGLYNDLGTNQTTTSVRLQAVNAKLIYDIAT
                     KTNKKKRVWVKVIRKNKEKGPFGVYTLAGTTGKIKNKKKRIDPTDPSIKGNKKIYSYAM
                     SILNGLK"
     CDS             complement(7140..8162)
                     /locus_tag="ctg119_4"
                     /transl_table=11
                     /translation="MIYMSFFIGLILICKGGDWFVDAASKLSEILGIPKYVIGATIVSF
                     ATTMPEIIVSVAAALDGHSAMAIGNAVGSVSANTGIILALSLFFLPVAIKREEYLFKNS
                     LYIGTLLLLLISFKDRIFDRADCLLLLLAGILFLVENVKNAVCKKELSNSKRKKEDVIL
                     HKKIQAGKNGEKKVKNKRSKWKEKQSSIWETFFWFCIGAVCIVAGSELLVHSACKIAEI
                     LHISEDIISVTIVAMGTSLPELVTTVTAILKKESSLSVGNIIGANMIDSAFILPICTLL
                     SGEKLPVSLQMAQIDMPLCILISVLALLPMLIRQKIKRRDGILVFSIYAGYLLYICWAI
                     "
     CDS             complement(8245..9039)
                     /locus_tag="ctg119_5"
                     /transl_table=11
                     /translation="MEQRKKIFGALDDLMRSPIGDRLRERVFRELSTKEIHDLLQREQK
                     PYKELMAYYQCALMEVETKFRVLNEQFSLAHDRNPIESIKTRVKSLESITEKLNRRNLP
                     FSTQSIEENLTDIAGIRIICSFREDIYFLADCLLEQDDITLIQRKDYIENPKENGYRSL
                     HLIVEVPIFLEHKKKMMKVEVQLRTIAMDFWASLEHKLKYKKDIASDQLTADLKKCADE
                     SAALDLKMDAIRKEIEVLKAPEAKAIGREVKHLPGGILNENQ"
     CDS             9421..10668
                     /locus_tag="ctg119_6"
                     /transl_table=11
                     /translation="VKKHIFLGVLLMLTGFFFIPSKTFAFQHAYESKSDFIYALARNEL
                     PVYYSDYSNDLKTVLPKYTGVKVIGYSGSWYEIQYASKKGGTKNGWVTRDEFHSDCLIY
                     DGREKQPFSNGTYQLSFYEENSSDSSFAMNTASIISENFSCSFKYAGDNRYTIRKAGEE
                     KYLKADTLSNTPSSNELWGSKQEAGTFLITRKKDYYTICDETTKRNLSQNDGSILEFTT
                     DSNAVWRLTRNKKAIEKENLQVFVQFDPVWAKHHYGNETTKDTDTNNFCTSGCGIFATV
                     NAIYSLSGHFPDPYELAQYASDKHYRIEDCGTDSGLFKAAAEKFGYKYGFSYDGSSESF
                     KELKEKLKEGDTAIVYLPGHYGTIVDYNAKKDKYLLMDPHYLPKRGTSSFGDWVSQKDL
                     EEGALMVQTFFYYKAE"
     CDS             11062..11910
                     /locus_tag="ctg119_7"
                     /transl_table=11
                     /translation="MLWEGGLHMNLRQINELWNEYKEKYDLPKDVQISAVQYDAEKYIE
                     GFFNILELLDGKYILHLNPRFHLYSDSYARFILFHEFTHFYDFINSSFDETEDLFIYMN
                     AYSEFHACRVTLARFMERLTLKTVHIDKIQIPGPFNEISIRHLLEEGLWRVKVCFEQFL
                     ETLEPNDFVMTFRQLMYLLGYISLFENDDVLLEQTLQFAHLDTDDFFALYHALKEIDYD
                     EILRLTRKIYNSAFLIYLRGFFRRNYDKRILPDDELENITADNCDEYKAILDKRQQEVA
                     A"
     CDS             complement(12330..13586)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg119_8"
                     /sec_met_domain="Aldedh (E-value: 4.7e-12, bitscore: 36.2,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKEILTQAVTAKNAINSADTETKNKALANMADALLAHTDAILE
                     ANKQDVEAARGKISDVMIDRLMLDAGRIEGMAKGIRELIDLDDPAGKVLRTVERPNGIV
                     IEKTAVPMGVIAIIYESRPNVTSDAAALCIKSGNVCVLRSGKEAWKSANAVVTALKEGM
                     VKSNLPGEGIQLIEDTSRESSVELMKAVGYVDLLIPRGGPGLIRSCVENAKVPCIQTGT
                     GICHVYVDESADFEKALQIIENAKTSRPSVCNAEEVLLVHSAVAEKFLPLLQKKLVEER
                     KEKGEIPVELRLCDRAAKIISGTLAGADDFDTEFLDYILAVKIVDSVEEAVEHISKHST
                     GHSEAIITESKEAADYFTMRVDSAAVYVNVSTRFTDGGEFGLGCEMGISTQKLHARGPM
                     GLEELCTYKYIIRGEGQIR"
ORIGIN
        1 aaacacgcat taggtattga tattggttct actactgtta aggtaacagt tatcaatgag
       61 agtcatgata tccttttttc cgattacaaa cgacattttg caaatattaa aggaacttta
      121 cagaccttat tatctgaggc gagagaaaag ctgggcaatc tcataatcca tccaaccgta
      181 actggttccg gtgggatggc aatctcagaa tacttacata ttccattctg tcaggaagta
      241 gtttgtgtgg caaatgcctt acaggattat gaaccaaaaa cagacgtagc aatcgaactt
      301 ggcggtgaag acgccaagat tatttatttt aataacggaa ttgagcagcg tatgaacggt
      361 gtatgtgccg gtggtactgg ttctttcatc gaccagatgg caagtctttt acagacagat
      421 gcaaccggtc ttaatgaata tgcccgtgat tacgataccc tctatccaat cgccgctcgt
      481 tgcggtgttt tcgcaaagtc tgatattcag ccattaatca atgagggggc aacaaaagaa
      541 aatcttgctg cttctatctt ccaggctgta gtaaaccaga caatcagtgg tcttgcctgt
      601 ggtaaaccaa tcaagggata tgtcgctttc cttggtggtc ctcttcactt tatgccagaa
      661 ttaaagaatg catttatccg tactttaaat ctggacgaag aacatattat cgaccctcca
      721 tactctcatc tttttgcagc aaaaggtgcc gcattaaacg caaaggaaga atgttccttc
      781 acattagatg atctcttaaa agagtttgaa tccgacattc agcttgctgt agaagtagaa
      841 cgtatggagc ctctttttaa agacgaaaaa gaatatgatg aatttatcga agagcacaac
      901 caattcaagg tgaaaaaggc agacttagct acctacagtg gcaaatgcta tctcggtatt
      961 gatgccggat ctacgacaac aaagcttgct ttagttggag aagatggttc cctcttatac
     1021 cgtttctacg ataataataa cggaagtccg ttaaatacaa caattcgtgc tatgaaggag
     1081 ttaaaggagt tacttcctcc tgctgcgaag atttccggtt cctgttctac tggttacggt
     1141 gaagcattaa ttaaggctgc actgcagctt gaccacggcg aagtagagac aatggcacat
     1201 tactatgctg ccgctttctt cgagccagat gtagactgta ttttagatat cggcggacaa
     1261 gatatgaaat gtatcaagat tcgtaaccac gctgtagata atgtactttt aaatgaggca
     1321 tgttcttctg gatgtggttc tttcatcgaa actttcgcaa aatctctgaa ctattctgta
     1381 gctgattttg caaaggttgc gctgtttgcc ccatctccaa tcgacttagg ttcccgctgc
     1441 actgtattta tgaactccaa agtaaaacag gcacaaaaag aaggcgcaag cgttggtgat
     1501 atttctgctg gccttgctta ttccgttatc cgtaatgcct tattaaaagt tattaagtta
     1561 accgacccca aacagcttgg taaaaaaatc gttgttcagg gtggtacatt ctataatgat
     1621 gcggtacttc gaagctttga acgtatttcc ggctgtcacg ccgttcgtcc agatattgcc
     1681 ggtatcatgg gtgctttcgg tgcagcctta attgcaagag agcgtgagga agaaactgga
     1741 gatacacaga tgctctccat cgacgagatt atcaacttgg aatacagcac ttccatgagc
     1801 cgctgtcagg gatgtaacaa ccactgtatc cttaccatta ataagtttaa caacgaccgt
     1861 cagtttattt ctggtaaccg ttgtgaacgt ggtcttggcc ttgaaaagaa tcatgagcat
     1921 gtaccaaacc tttacgaata taaatataaa cgaatttttg gatataaagc attaaaacca
     1981 gacaaggcaa aacgtggtgt tatcggtatt ccacgagtac tgaatatgta tgagaactat
     2041 ccattctggt atacattctt tacaaacctt tctttccggg tattgctttc tccaaagtct
     2101 tcccgaaaga tttacgaact tggtattgag tccattccaa gtgaatccga atgctatcct
     2161 gcaaagattg cacacggaca tgtaatgtgg cttttaaaga agggtatcaa caccattttc
     2221 tatccttgtg ttccttatga ggaagatcag atggaaggtg ccaacaacca ttacaactgc
     2281 ccgatcgtaa catcttatgc agaaaatatt aaaaacaaca tggaagagct ccgtgatccg
     2341 aatgtccttt ttatgaaccc attcttagca ctcgataatg cagatgcctt gaaggtacgt
     2401 ctttatgacg agttatctaa acatttcgat gtgacaaaag aagagattga ccatgccgta
     2461 gatgaagctt ataaagaagc tgcacaggta agaaaagatg tacaggcaaa gggcgaagaa
     2521 acacttgctt atctcgcaga aactggaaag atgggtattg ttctttgtgg tcgcccttac
     2581 catatcgacc cagagattaa ccacggtatt cctgaactga ttaactcttt tggcatcgcc
     2641 gtattaagtg aagattccat ctgtcactta ggtcatgttg agcgtccatt aatcgtttct
     2701 gaccagtgga tgtatcattc ccgtctgtac gctgccgcaa actacgcaaa gaagaacaag
     2761 cagttagaag tcattcagct taactctttt ggctgtggtc ttgatgcggt aactaccgac
     2821 caggtaaatg atattatgac gaattccgga cgtatttata ccgtccttaa gattgatgag
     2881 gtaaataact taggtgccgc cagaatccgt atccgttctc tgattgctgc cgtaaagatc
     2941 agaaaccgta agcacattga gccacatccg gttccggcaa atatcgaaaa agtagaattt
     3001 acaaaagaaa tgaaaaagga ctacaccatt ctgattcctc agatgtcccc aattcatttc
     3061 gacctgctca cccctgcctt ccgtcactgt ggctataacg tagagatttt gccggaaatg
     3121 ggaaaacagg cagtagatac tggattaaaa tatgtaaata acgatgcctg ctatccatcc
     3181 cttatcgttg ttggacagat tatgactgcc ttaacttccg gcaaatacga cctgaacaaa
     3241 acagccgtta tcatctccca gactgggggt ggctgtcgtg cgacaaacta tatcggattc
     3301 atccgccgtg cattagctaa gaacggttac ggtcagattc cagttatcag tttaagcgta
     3361 cagggaattg agaagaatga aggttttaaa ttcactccgt cacttttagt tcgtgccctt
     3421 cagggagtta tttacggaga tttatttatg cgtgttctct accgcgtccg cccatacgaa
     3481 aaagtaaaag gttctgcaaa tcatttacat gaagtatgga aaaagcgttg tattaaatct
     3541 cttgagaaag cacgatatgg agaatttaag aaaaatatcc gcggcattat ccgcgacttt
     3601 gacagattac caatcacaga tgagaagaaa cctcgtgttg gtatcgttgg agaaatcctc
     3661 gtaaaattcc ttccagacgc aaacaaccat ctggtagaac ttttagaaga agagggggca
     3721 gaggcagtaa tgccagattt attagacttt atgttctact ccttctacaa tagtaatttt
     3781 aaagcagaat atctcggaaa atctacaaaa gctgctaagt tatgtaatat ggcaatctct
     3841 gcactggaag cttaccgagg cttcctgcga aaagaattag aaagaagcga tcgtttcact
     3901 gcaccacctc acattgagga acttgccgag tacgcaaaac caatcgtatc cctcggtaac
     3961 cagaccggtg agggatggtt cttaactggt gaaatggttg aacttatcaa acagggcgcc
     4021 ccaaatattg tttgcacaca gccatttgcc tgcctgccaa accacgttgt aggtaagggt
     4081 gttatcaagg aactgcgccg taagtatccg gaatctaata tcgtcgcaat tgactacgat
     4141 ccaggagcaa gcgaagtaaa ccaggtaaac cgaattaaat tgatgctggc aacagcggag
     4201 aagaagttga aatctgattt gccgcaggca agatagacgc caaacaaacg ccctctgaga
     4261 atgaaagaat ccttatttgt gactttagtc gcggcgtgtt gaatactcgc tctactcgct
     4321 cttatccaac acttgctccg aggccacaaa taaggtttct ttcattctca gagggctgtg
     4381 ctttggatgt ggaagaaaaa aatggaattt attattaaag aatttggaaa ttcgtaaaag
     4441 gctgtctttg gctgctgaag ttaaatcaga attcatgttc aagtatttgg ggattcgcca
     4501 gaaggttgcg gttttacgaa aaatatagca attctataac atggtattcg aagaataggt
     4561 ttattctatt ctgcaaatca gtgaaaaaaa ttgagaaaat aaattgtagc cttatctttt
     4621 atgtactctg tcataggaaa aatgtatttt gaaaattcac aatgttctgg agaatctcca
     4681 aattcccaac aggaatttct ggcgttactt cagtagccac cgtcagaaac atagcaggcc
     4741 aatacctcct atttgtggcc tcggagcaag tgttggatga gagcgcttta agcgaacatt
     4801 caacacgccg cgactaaagt cacaaatagg aggtttggcc tgctatgttt cgtcaacttc
     4861 gcctgctaca gttccgcagc aaattccctc aacttctgtt ttgcttttgg agacagattc
     4921 ttcggaacct gcacctctat cgtcgtatac tggtcaccat gtacagaaga attcttcatg
     4981 gagacgatac cctttccgcg gagtcttaat ttacttccgg attgtgttcc cggttttatg
     5041 ctacagcgga cattaccata aatggtcggt acggtgacat ctccgccaag aacggctgtg
     5101 ataaatggga tagttactgt gttaaaaata tcctgaccgt ctctcttaaa acctggcttt
     5161 tccgaaacgg ttactttcaa gaataaatca ccggcagttc caccattata gccgggagtt
     5221 cccttgcctt ttaatctgat actctgtccc gtttctattc ctgccggaat attaacttct
     5281 aatgcctgca ctttgccatt ttcatctttt aagtgaatgg tttccttttt accgaaagcg
     5341 gccgcatcaa aacttacctt aatgtctgca tgaacatctg aaccttttgt ctggtaagat
     5401 tggcggtttc caaagcctcc gttttgtcgg gaattgccgt gaaagccatt attaaagttt
     5461 ccattttgac tgaatccgcc tctgaaacca gattttttaa agcctccgcc aaaaaagttt
     5521 tcaaagatat ctcccatatc accgccttca aaatgaaact cctgataacc attgccgtta
     5581 ttcgagcggt atgtgcctcc gtgaaaacct ccgcttcccc cgaagtcact aaaacctcca
     5641 aaacctccat cgttaccata cgggccagac tgtgcatttc ccgttccatc aaaggcagca
     5701 tgaccaaaac gatcatagag tttctttttc tctggatcac ttaaaacttc atacgcttct
     5761 gtcacttcct taaattttgc ttcggcatta ctatccccag gattaatatc tggatgatat
     5821 ttcttcgcca atttacgata ggccttttta atagtcttct catctgcatt tttatttatt
     5881 ccaagaacat cataataatc tgtttttgtt accataatct tcaccctctc attgtgaatt
     5941 ctatttgttc tagttgaaat ataacactgt attttcttat tgtcaactct ttctttaaaa
     6001 cacgctctta aaagcctttc catcttcttc cacgcaaatt tcagaaaagg ctcttttatt
     6061 gactttatct ttcttttcct ttatactatt atagatatta aatcacaaaa gaaaggaaag
     6121 gtataatgaa aaaagttaca tcgttattaa tggcacttat tctgtctgtt actattttaa
     6181 tgggcagtat tccaatgaat gcctcagcag ctactacaga agttcctgtt ggctggtatc
     6241 agcagggtaa aaaagtatat tactacgaaa atggtaagaa agttactggc tggcatacat
     6301 taaagagcta ctacgacaag aaaaagtaca aattctactt caacaaaaac ggagtattag
     6361 ttacggattt atttacactt aactacaaaa aatggattaa ggaagacatt acgatcgttg
     6421 ttaacacaaa gacacataat gctactcttt atgccaaaga taaacagact ggcaagtata
     6481 acattccatt aaagactatg gtttgctcta cttcaagaaa ggcaaaagga acaaaggctt
     6541 attctggatg ccgtctggaa aaaacttctg ctgtaagatg gttcatctac aagaaaagcc
     6601 gtccatatca ttattaccag tggggtgtta aggtaaaaca tggtaacttc tatttccatt
     6661 ctgcacgata cactactaca aataacagaa agttagaagt tggtttatat aacgaccttg
     6721 gaacaaacca gacaacaaca agcgttcgtc ttcaggctgt caatgcaaaa cttatctatg
     6781 atattgctac aaagacaaac aagaagaaac gtgtctgggt taaagtaatc agaaagaaca
     6841 aggaaaaagg acctttcggt gtttatactt tagccggaac tactggaaag attaaaaata
     6901 aaaagaaaag aattgaccct acagatccta gtattaaggg aaataagaag atttactctt
     6961 atgctatgag tattttaaac ggtcttaaat aattttctaa taaaagaagc attgcttcat
     7021 taaatttacc tgtctgtgac atgagcagca ttctattttg tttatcagac aggtattttt
     7081 ataagctaat gattcttttt attttcttgt tagaagaggg taaagcaaat atgttcacat
     7141 tatatagccc agcagatata taatagatat ccagcataaa tggaaaaaac aaggatacca
     7201 tctcttcttt taattttctg acgaattaac ataggaagaa gcgcaagtac tgaaataagg
     7261 atacataaag gcatatcaat ttgtgccatc tgcagtgaaa ctggaagttt ctctccacta
     7321 agtaatgtac agattggtaa aataaaagcg gaatctatca tatttgcacc tataatattt
     7381 ccgacagaca aagaagactc tttttttagg attgctgtaa ctgttgttac aagttccggc
     7441 aaagatgttc ccattgcaac aatcgttacc gagataatat cttcgctgat atgcagaatt
     7501 tccgctattt tacaggcaga atgtactagt aactctgaac ctgctacaat acacaccgcg
     7561 cctatacaaa accagaaaaa tgtttcccat atactacttt gtttttcttt ccatttactt
     7621 cttttatttt ttaccttttt ttctccgttt ttcccagcct gtattttttt atgtaatatc
     7681 acatcttctt tttttctttt actgttggaa agttcttttt tacaaactgc atttttgaca
     7741 ttctctacaa gaaataaaat cccggcaagt aatagcagga gacaatcagc cctgtcaaat
     7801 attctatctt tgaagctaat caataacaac agtaatgttc caatatataa gctgttttta
     7861 aacaaatatt cttctctttt aattgcaaca ggaagaaaaa ataaactaag cgcaagaata
     7921 attcctgtat ttgcagaaac agaaccaact gcatttccta ttgccatggc agaatgccca
     7981 tctaacgcag ccgccacaga aacaatgatt tccggcatcg ttgttgcaaa actcacaatc
     8041 gttgctccga tcacatattt cggtattcca agtatttccg ataattttga cgcagcatca
     8101 acaaaccagt ctcctccctt acaaataaga atcagtccaa taaaaaaaga catataaatc
     8161 atatatagcc ctcctgccct atatctcttt catatgtctt ttttcggtat ttatacctgc
     8221 tttttttata tgccttatat atttttattg gttttcgttc agaattcccc ccggcagatg
     8281 cttcacttct cttcctattg cttttgcttc cggtgctttc aaaacttcta tttctttgcg
     8341 gattgcgtcc atcttcaaat caagggcggc actctcatca gcacatttct ttaaatccgc
     8401 tgtgagctgg tcagaagcaa tatctttctt atattttaat ttatgttcaa ggcttgccca
     8461 gaaatccatt gcaattgtac gaagctgtac ttctactttc atcattttct ttttatgctc
     8521 taaaaagata gggacttcca caatcagatg cagactccga tagccattct ccttcggatt
     8581 ctctatgtaa tctttacgct gaatcaatgt gatatcatcc tgctctagca gacaatctgc
     8641 aagaaaataa atatcttctc taaatgagca gataatacgg attcctgcaa tatctgtaag
     8701 attctcctca atactctgcg ttgaaaaagg aagattcctt ctgtttaact tctctgtaat
     8761 gctctcaaga cttttcaccc ttgttttaat cgactcaatc ggatttctgt catgtgccag
     8821 tgaaaactgt tcattcagca cacgaaactt tgtctctact tccataagcg cacactggta
     8881 atatgccatt aattctttat atggtttttg ctctctctga agcaaatcat gtatttcttt
     8941 tgtagataat tcccggaaca ccctctctct gagtctatcc ccgattggtg aacgcattaa
     9001 atcatctaat gctccaaaaa ttttctttct ctgttccatt cttcttcatt cctttcatat
     9061 cgtatttcca cgacaagtag aatactctgt ctaattttac cataaattgt tgtttatctc
     9121 aattcatttt ctatatctta cttcacaatt ccttatacaa ttttctaaag atgtttgttt
     9181 gcaaattcga tattctatgc tataatacct caagttgtaa cactttttta atatttgtaa
     9241 gacatttgta actatttaaa tatcttcaaa atacaaaata atgaatagat gcttcttatt
     9301 tttttatttt aaatctgtaa aaacatctta taatcatgtt ctcctggaat cttttttaca
     9361 aagtcaagtg tagaaaagac tttaggaaca aacacataat acattaatgg aggaattgtt
     9421 gtgaaaaaac atatcttttt aggcgttctt ttaatgttga ccggattttt ctttattccg
     9481 tcaaaaactt tcgcttttca acatgcctac gaaagcaaat ctgactttat ttatgcccta
     9541 gcaagaaatg aactgcccgt atactattct gattacagca atgatttaaa aactgtactc
     9601 cctaaatata ccggtgtcaa agtaatcggt tattccggtt cctggtacga aattcagtat
     9661 gcttctaaaa aaggcggaac aaagaatggc tgggtaacaa gagatgaatt tcattctgat
     9721 tgcctgattt atgatggcag agaaaaacag cctttttcaa acggtaccta tcagctttct
     9781 ttttatgagg agaattcctc ggattcttct tttgctatga atacagcttc tattatctca
     9841 gaaaattttt cctgttcttt taaatatgct ggtgacaacc gttacaccat acgcaaagca
     9901 ggagaagaaa aatatttaaa agcagataca ttatcaaaca caccttcttc aaatgaactt
     9961 tggggaagta aacaggaagc tggtactttt cttattacaa gaaaaaagga ctattataca
    10021 atctgcgatg aaactaccaa aagaaatctt tctcaaaacg atggcagtat tttagagttc
    10081 acaacagatt ctaatgccgt atggcgtctg acccgtaata aaaaagcaat cgaaaaagaa
    10141 aatcttcagg tttttgtcca gtttgaccct gtctgggcaa agcatcatta cggcaatgaa
    10201 accacaaaag atactgacac aaataatttt tgcacttccg gctgcggtat ttttgccaca
    10261 gtaaatgcta tctactcttt aagcggccat tttcctgatc cttatgaact ggcacaatac
    10321 gcttctgata agcattaccg catcgaagat tgtggtactg acagcggact ctttaaggca
    10381 gctgccgaaa aatttggcta taaatatgga ttctcctacg atggaagcag cgaatccttt
    10441 aaagaattaa aggaaaagtt aaaagaagga gatactgcta tcgtctatct tccaggacat
    10501 tacggtacta ttgttgatta taatgccaaa aaagataaat atctgttaat ggatccccat
    10561 tatcttccaa agagaggaac atcttctttc ggagactggg taagccagaa ggatttagaa
    10621 gaaggtgcat tgatggtgca aacttttttc tactataaag cggaatagta ttgaagtaac
    10681 agacgaatcc cgaaagctaa gtactgtata tctgtgactt tcgtcgcggc aggttaaacg
    10741 ttcgcttacg cgctcacatc taacctttgc tcccaggcca cagatataca gtacttagct
    10801 ttcgggattc tgttttttgg ccgcctcaat gtagtattgg tacagatatt ggaaaataag
    10861 tttttaagga aagatttgac aaaccttcca cctgctattt caattcaaat aatagaaatt
    10921 atgtaaaacc ttctagaacg tgtttgaaac atgctctagc ctcccttttt ccgtctattg
    10981 aatcaaatca caataattta tccgtcttcc tcctatttga gcgttgttat ttctatatga
    11041 gtgttatata atataagcaa tatgttatgg gaaggcgggt tacatatgaa tttaagacag
    11101 attaatgaat tgtggaatga atataaggaa aagtatgatt taccaaagga tgtgcagatt
    11161 tcggctgtgc aatatgatgc agagaaatat attgagggtt tttttaacat tttagagctt
    11221 cttgacggca agtacattct acatttgaat cctcgttttc atctttatag tgacagttat
    11281 gcccgtttta tccttttcca tgaatttact catttttatg atttcataaa cagttctttt
    11341 gatgagacag aagacttatt tatttatatg aatgcctatt ctgaatttca tgcctgccgt
    11401 gttacactgg cacgttttat ggagcgcctt accctaaaaa ctgtacatat agacaagatt
    11461 cagattccag ggccatttaa tgagatttct atccgtcatc ttttagagga ggggctttgg
    11521 agagtaaaag tttgttttga acagtttctt gaaacacttg aaccgaatga tttcgttatg
    11581 actttccgtc agttaatgta tcttctcggt tatatctctc tttttgagaa cgatgatgtt
    11641 ttattagagc agactttaca gtttgcacat cttgatactg atgatttctt cgctttatat
    11701 catgctttaa aagagattga ttacgatgaa attttaagac ttacaagaaa gatttacaat
    11761 tctgcatttc tcatatattt aaggggattt ttcagaagga actacgacaa acgtattctt
    11821 ccggatgacg agcttgagaa tatcacagca gataattgcg atgaatataa agcaatcctt
    11881 gacaaacgac aacaggaggt tgcagcttaa ggttgagaat aaacagatgc tctcataagt
    11941 tcttattata taaaaatgct tcatatcact gcactcaaaa tacgcaaccg tattttgaac
    12001 ttgctctaga gcgtgttttt atatactaag aacttatgag ggctgtttat ttttaaattt
    12061 aaggcagcaa cgctatagat ataagatttg gggaagatgg ttgaaggatt agaaattccg
    12121 aaagtcaaat ctttttggac tgatttataa agttttttta tagtgaacag aaggcaggaa
    12181 atgaaatact ctatatttgt ggcctcggag cacgtgttgg atgtgagcgc ttaagcgaac
    12241 attcaacgcg ccgcgactaa agtcacaaat atagagtatt tcgtttcctg ccttcgttgg
    12301 tttagagcgt gtttaaaaaa tgctctagac tatctaatct gtccttctcc ccggatgata
    12361 tatttataag tacataattc ttctaagccc attggtcctc tggcatgaag tttctgggtg
    12421 gagattccca tctcgcatcc gagtccaaat tcgcctccat ctgtgaagcg ggtagaaacg
    12481 ttcacatata ctgcggcact atctactctc atagtaaaat agtctgctgc ttcttttgat
    12541 tctgtgataa ttgcttcact gtgacctgta gaatgttttg aaatatgctc tactgcttct
    12601 tccacgctat ctactatttt taccgcaaga atgtaatcaa ggaattctgt atcaaaatca
    12661 tctgccccag ccagtgttcc tgaaataatt ttagcggctc tatcgcaaag acgcagttcc
    12721 accggaattt cacctttttc ttttcgttct tctactaatt ttttctgtaa taatggcagg
    12781 aacttttcag caactgcgct gtgaacaaga agaacttctt ctgcattaca aacgcttgga
    12841 cggctggttt tggcattttc aatgatctgt aatgccttct caaaatcggc gctttcatcg
    12901 acatagacat ggcagattcc tgttccggtc tgaatacatg gtactttggc attctctacg
    12961 caggaacgga taaggcccgg acctcctctt ggaatgagta aatccacata accgactgct
    13021 ttcattaatt ctacagaact ttctctgctg gtatcttcga taagctggat gccttctcct
    13081 ggaagatttg actttaccat accttctttt aaggcagtaa ctacagcatt cgcactcttc
    13141 cacgcttctt ttccacttcg aagaacacag acattaccac tcttaataca aagggctgct
    13201 gcatcgcttg ttacatttgg acggctctcg taaataattg cgataactcc cattggaact
    13261 gctgtctttt caatgacaat tccatttggg cgttctacag ttcttaatac ttttccggca
    13321 gggtcatcta agtcaatcag ctctctgatt ccctttgcca ttccctcgat tcgaccagca
    13381 tctaacatta agcggtcaat catgacatca gaaatctttc ctcttgctgc ttccacatcc
    13441 tgtttatttg cctctaaaat tgcatccgta tgtgctaaaa gggcatccgc catattggca
    13501 agtgccttgt ttttagtttc ggtatctgct gagttaatcg catttttcgc tgtgactgcc
    13561 tgtgtcagta tctctttcgt tgtcatgctt ttttcctccc gataaacttt gttcccacct
    13621 tttctccatc aataatattg tagagaagtt ctggttttgt tccgttagca ataatcatat
    13681 caatgccggc attcattgcg atttctgccg catgaatctt tgtaatcatt cctccagtac
    13741 caagtgttgt tccttttgta cctgctaatt cttttatttc cggagtaata gaaaatacag
    13801 tatcaatcaa ctgagcatcc gggttattac gcgggtcgcc ggtataaaga ccatcaatat
    13861 cacttaaaat aatcaataaa tctgcatttg cattctctgc aacgattgct cccattgtat
    13921 cattatcacc cacagaaatt tcctgtgttg caatggtatc attttcattg ataatcggaa
    13981 taacatttaa ctctaacaga cggtttaatg tactctgaaa attcttgtgg ctttcttcat
    14041 ttgaaaagtc aagcccggta atcagcatct gtgcaacgat atgattatat tctctgaata
    14101 atttatcata aagatacatc agttcacact gtcctatcgc tgctgcggcc tgctttgtgg
    14161 gcatatcttc gggcttactt ttcatattca gtttaccgac acccataccg atagcaccgg
    14221 aagataccaa aataag
//
