LOCUS       gnlProkkaKKHFPLKO_195  12166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KKHFPLKO_195.
ACCESSION   gnlProkkaKKHFPLKO_195
VERSION     gnlProkkaKKHFPLKO_195
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:44:12
            Original ID  :: gnl|Prokka|KKHFPLKO_195
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4276
            Orig. end    :: 16442
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12166
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:7166]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7166
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12166
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12166
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(47..748)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 147.4; E-value: 7.5e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg195_5"
                     /transl_table=11
                     /translation="MIKLLLVEDDVNLSYIVQAGLQDIIGGYEVTVAENGKEGIETWKN
                     WKPDIIISDIDMPVMNGFEMVKRIRETDGEIPILFASALTSPKDVRKGYDIGVNNYVKK
                     PFVPDELDAHLRAILKLKEGKKNRNEEGLCNFGQYTLNPKHATLLNNQTDKQSILTVRE
                     AEILQILAENKVEIVRKEAILSRFWNTEDDYFASRSLDVFIAKLRKLFADDTQIEIVTK
                     RGTGYILVIKE"
     CDS             complement(745..2046)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 166.6; E-value: 2e-50)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg195_6"
                     /transl_table=11
                     /translation="MQHIYIRIITIISIFFALTLQGIWLRNSFYLYKNQLEESINNLFA
                     KATLEEATTHFSELPKGTIFLGAPRTNNTGTYPEVTYLLESLGTYGITNNINRLDSIFK
                     EMLFEHKINTDLYIEKIKNGNIVETTCQSNIKRFGIIRTQPIPIKLDNSSNVQAIITIP
                     YYNIFRQMLILIIATAIMMIFIIGCIVYQIKIISKLNKIFKIREDFSYAMVHDMKTPLS
                     SILSALNFLQGGRLDNKPDMKEKFFNIAKDEADHLLTLTNKILTISKLENNKLEMNCEM
                     VVLKPLLLKISEKFMAKSPKNITFKFDLQAESIYADAEYLEEVFCNMIDNSIKYSKDNV
                     DITISSSENSKYSIIKIYDNGLGINEDDQLKIFNKYERAYAGHRKRTHVAGFGLGLNFV
                     QQVIEAHKGKIIVNSVEGEFTEFIIYLPLIIKEL"
     CDS             2143..2274
                     /locus_tag="ctg195_7"
                     /transl_table=11
                     /translation="MKTERKYVDELTFEECSKINGGKSELIGWAEINGVWIAVYRDV"
     CDS             2386..2541
                     /locus_tag="ctg195_8"
                     /transl_table=11
                     /translation="MKKKKMKTLEIEELKNVSGGVAPGPNGEGCTEHWLPDFLKDKTLL
                     DILKHK"
     CDS             2890..3051
                     /locus_tag="ctg195_9"
                     /transl_table=11
                     /translation="METKNVIREMSMCEMMDANGGGFFFSSASTWFWRGLGIGATAGGL
                     GASIALSA"
     CDS             3157..3312
                     /locus_tag="ctg195_10"
                     /transl_table=11
                     /translation="MKELTQQELKGINGGVAPIVAAVCFCSGVGAGVVVGALGVYYGYE
                     LVKSMM"
     CDS             3801..4976
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 106; E-value:
                     3.2e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg195_11"
                     /transl_table=11
                     /translation="MNMLLPDEWIENSIETYIYQHTTKSQIIYWIVLFAVTVTLVALPF
                     IYVDISVQGSGVVRPVAEKAEITSSITEIVDSVFVKEGEQVNKGDVILRFRTNSSDYKI
                     NYQTSRLNDCSAQLADLAYLAEGNCPKLFSSPVRQQEYAYFIRKKQELETGLAQAEKEY
                     LRNKTLFEKKVISEEEYDSYYFKYKSQQNELASLVQSQISTWQADQNTYRNTYNEMSTN
                     LKQEIKDKDMYIVRSPVDGTVDQFSGVYRGSSIQAGQSLAVISPDSTLCIEVYVTPRNI
                     GFMNIGMPVNVQVESFNYNEWGTIPGRVKDISSDFLTDSQGNSFYKVKCEMERDFLQLK
                     NGRIGKLKKGMTVNAHFMVTRRSLFDLLYQKMDGWVNPKQYENETMVAKLN"
     CDS             5001..7166
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     253.5; E-value: 2.6e-77)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 333.6; E-value:
                     3.7e-101)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_12"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.9e-35, bitscore:
                     110.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 5e-165, bitscore:
                     541.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRKGIKIKQHDITDCGAACLASVCAHYGLQFPVARIRQYAFTDQ
                     KGTNVLGMIEAANRLGLSAKGVRAQFEALSIVPKPTIAHVIVHEHLQHFIVLYKVEKEH
                     ITYMDPGDGKMHKVTNAEFQKMWTGVLVLMEPEETFKKGNMKTSMTRKFFSLLAPHKSV
                     MMQAVFGALIYSILGLSTSVYVGKITDYVLVDGNINLLNLMGIVMIIILILRTFIGSMK
                     SILALKTGQRIDAALILGYYKHLLTLPQQFFDTMRVGEIISRVNDAVKIRNFINNVSLD
                     LLVNMMILLFSVGLMFVYSWKLALVTLASAPLFLLIFWAFNKLNRKYQRSIMESSADLE
                     SQLVESINSISTIKRFGIEDFANLKTEIRFVHLLKNTYRSIYGAIMAQGGIQFVSTAIT
                     IAVLWMGSVLVIDKELTPGTLMVFYSLISYVISPIGSLISSNQTIQDALIAADRLFQIM
                     DLEREQDDSQKIELRKDMIGDIVFENVSFRYGSRKEVFNGLNLKIDKGKTTAVIGESGS
                     GKTTLISLLQHIYPIQSGQIRIGGYDISQISNKSLRSLVGTVPQQIELFAGTIIENIAV
                     GDLQPDMKRIVDLVEQLGLKDFIERLPNGYMTYIGEHGASLSGGERQRIAIARALYKEP
                     EILIFDEATSSLDSISEKHVKRTLDALASSGKTVIIIAHRLSTVKNADMIVVLDNGKVS
                     ETGTHKQLFDSNGIYNRLWNEQFDQLD"
     CDS             7226..7408
                     /locus_tag="ctg195_13"
                     /transl_table=11
                     /translation="MERTNEKKIVALSEKESQQIEGGIVQFLLGAIIGGFIYDCISEPG
                     HCINGFRDGMNNGLK"
     CDS             7417..7563
                     /locus_tag="ctg195_14"
                     /transl_table=11
                     /translation="MKDLTMTDMVNIHGGSTFSYYVFWFLGRSFVSPAELDKNGMNPVH
                     LWN"
     CDS             7782..8132
                     /locus_tag="ctg195_15"
                     /transl_table=11
                     /translation="MNKKLFLYGILIAAVGLILSHTYRPYIYSHNLFDFHLADVIGSIV
                     CVPSSVLFFYGMDPRYSVKKYTVYATIVYISYELLGLFNIHGTFDIYDIIAIIISAFCF
                     YRIYIRLSKKTH"
     CDS             8435..9754
                     /gene_functions="transport (smcogs) SMCOG1076:RND efflux
                     system, outer membrane lipoprotein, (Score: 156.9; E-value:
                     1.1e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg195_16"
                     /transl_table=11
                     /translation="MKRLIFILVIVGLFSCSGYAQEKKWTLSECIDYAVTHNIEVRQSV
                     NQIQNLKVEKNTLRNSFLPNLKAGASHNFTFGRSLNQSNTYENSNIQNSSFSVSTEIPV
                     FMGFKRTVAVTQNKFDLLAAEAKKELIKNNLLINVAGAYFQILLNKEIYNIALAQIQLT
                     KEQEVCTKILIDNGKAPESQLYDVRAQLADDELAATEARNSLRLSYLDLAQLMELDEYE
                     EFDIDSIDGDVAIADTLNLMNIYQSALTCMPQILQAFYALQSKTKGIKIAQSGFYPTIS
                     FVAGMSTNYYNNTSALYENFRKQFNNHMQKSLCLTVSIPLFDRFSVRNKVRSARIEENN
                     ARLSLENEKKQLYKDIEQAYTAVISAYEKYRSTTKAVMANKEAHRYALEKYAAGKSTVF
                     EYNEIKMKLADALSQQFQAKYTYLLKDRILAFYSYFTLTD"
     CDS             complement(10138..10314)
                     /locus_tag="ctg195_17"
                     /transl_table=11
                     /translation="MKSLLKNLGVILVIIGAVILVVCFATGNVNNNAILGTSLALVVLG
                     LISYIVLNKRITD"
     CDS             10486..10785
                     /locus_tag="ctg195_18"
                     /transl_table=11
                     /translation="MKVEHDEQKKKFFVKVDGYEAHVAYDVHDGAWDIRHTVVPKPIGG
                     QGIASMLVKQVYDEARARGMKCMATCSYAVLWLQRHPEYEGIVSDDHAPDACAL"
ORIGIN
        1 tcgaggtacc aaaaaaggga agacttactg atttaccaat aacagtctat tccttgatga
       61 caagtatata tcccgtacct cttttggtga caatctctat ctgagtatcg tctgcaaaca
      121 gttttcttag tttggctatg aatacatcaa gacttcggga tgcgaagtaa tcatcttccg
      181 tattccagaa gcggcttaga atggcttctt ttcttactat ttctacttta ttttcagcaa
      241 gaatttggag aatttcagcc tctcttacgg taaggattga ttgtttgtcc gtttggttat
      301 taagcaaggt agcatgttta gggttcagtg tgtactgacc aaagttacat aatccttctt
      361 catttctgtt ctttttacct tcttttaatt ttaggatggc acgcagatgg gcatcaagtt
      421 catccggaac aaaaggcttt ttcacataat tatttacacc aatatcatag ccttttctta
      481 catcttttgg cgaagtcaag gctgaagcaa aaagtattgg aatctcacca tcagtctctc
      541 ttattctttt taccatctca aatccattca ttaccggcat atcaatatct gaaatgataa
      601 tatcaggttt ccagtttttc cacgtttcaa taccttcttt accattttct gccacagtaa
      661 cttcatagcc acctataata tcctgaagtc cagcttgtac tatatagctt aagtttacat
      721 catcttcaac tagcaataat tttatcataa ttcttttatt attagaggta agtaaataat
      781 aaattcagta aattctcctt ctacactatt gactatgatt tttcctttgt gcgcttcaat
      841 cacttgttgt acaaagttta agcctaatcc aaatcctgca acatgcgttc tttttctatg
      901 cccagcataa gctcgttcat acttattgaa gatcttaagt tgatcatcct cattgatacc
      961 aagcccatta tcgtaaattt tgataatact atatttacta ttttctgaag aagatattgt
     1021 aatatcaaca ttatccttgg aatatttgat ggaattatca atcatattac aaaatacttc
     1081 ttctagatat tcagcatcag cataaatact ctcagcttgc aaatcaaatt taaaagtaat
     1141 gtttttggga gacttagcca taaatttttc ggatattttt aagagtaaag gctttagcac
     1201 taccatttca cagttcatct ccagcttatt attctccaat ttcgatatgg tcagaatttt
     1261 gttagtcaat gtcaataagt gatcagcttc atccttggct atattgaaga atttctcttt
     1321 catatctggc ttattatcaa gtcttccacc ctgtagaaaa tttaaggcag acagtattga
     1381 actcaaaggt gttttcatat catgtaccat tgcatatgag aagtcttcac ggattttgaa
     1441 gattttgttt agctttgata tgatttttat ttgatatact atgcatccta ttataaaaat
     1501 catcatgatt gctgttgcaa taatgagtat caacatttgt ctaaaaatat tgtaatacgg
     1561 aattgtgata atggcttgta cgtttgatga attatctagc tttatcggta ttggttgtgt
     1621 tctaataatg ccaaaccgtt taatattact ttggcatgtt gtttctacaa tattcccgtt
     1681 ttttattttt tcgatataca aatcggtatt tattttatgc tcaaaaagca tttctttaaa
     1741 aatagaatcc agacgattaa tattattagt aatgccatat gttcctaagc tttctaataa
     1801 ataagttacc tctgggtatg ttcctgtatt attggttctt ggagcaccga gaaatattgt
     1861 tcctttaggg agttctgaaa aatgcgttgt cgcttcttct aatgttgctt ttgcaaacaa
     1921 attattgatg gattcttcta attggttttt atatagatag aaggagtttc ttagccatat
     1981 tccttggagt gttaatgcaa aaaatatact tatgatggtt ataattctaa tataaatatg
     2041 ttgcataatt gaaagataac attgtattaa cgataagtta acttgttgta gaaagtttag
     2101 cttttacttt tgcaaaagta acaattaaga attgtaaatt atatgaaaac agaaagaaaa
     2161 tatgtagacg aattaacttt tgaggaatgc tcaaaaatta atggtggaaa atcagaactg
     2221 ataggttggg cagaaataaa tggtgtttgg attgctgttt atagagatgt ataaatgaaa
     2281 taacattacg gtaacaaata gataactttt gagctgatag cttggattta tctttgcatc
     2341 agaaaataaa caaaaagtat aataacaatt aaataagaac agcgtatgaa aaagaaaaaa
     2401 atgaaaacat tagaaattga agaattgaaa aacgtaagtg gtggagtggc acctggacct
     2461 aacggtgaag gttgtacaga acattggttg cccgacttct tgaaagacaa gacacttctg
     2521 gatattctta aacacaaata gaagaagaat aatgtttgaa agaattagaa ataagaatag
     2581 tattaataaa aacaatgcct atgaaagaat ttaacaaaga tgagagtctg ttaataatag
     2641 gcgggtattt cccatcatca gaggattagt tgtaaaattt gtatcctatt gagagattta
     2701 tttttttttt ggtaaaaatt ctaattaaaa attatggata agaatgaaac gatgcttcgt
     2761 gccatgagta tgcaagaact atagaaaaca aacggaagca gaacttttgg tcttctgata
     2821 agtgtgattg tagatgctct agaagggaag tttatcatgt atatttaaca aactaaattt
     2881 tggattaata tggaaacaaa aaatgtaatt cgcgaaatga gtatgtgtga aatgatggat
     2941 gcaaacggtg gaggattctt tttttccagt gcaagtacat ggttctggag aggccttggc
     3001 attggagcta ctgccggtgg tcttggtgct agtattgcct taagcgctta atactatgaa
     3061 tatccagaag aagaaaggac aactattcta ttatggactc ataatagggt gtgtcatagg
     3121 aataataagt atgtcattaa ttttaattgc aaaagtatga aagaattgac acaacaggaa
     3181 ttgaaaggga tcaatggtgg agttgcacca attgtagcag cagtttgttt ctgttctggt
     3241 gtaggagcag gggttgttgt tggcgcattg ggcgtatatt atgggtatga attagtaaaa
     3301 tccatgatgt aattgtaacc tcctatcctt gtttgaagtg catattggaa atcctaatca
     3361 taaatgcttg aagaaacaaa tttcagatga gaaacagaaa atgtaattca caagttgacc
     3421 acatatgaaa ttaattttca gatatatgag ggtgttgaaa tttatttttt attcttgaat
     3481 ttataatttg aaattagagc attttgtaag actaaagaaa gggtcgtatc ataactcaat
     3541 atagtgtttg atacgaccct tttaaatatt attgttacaa tctataactt gtaggagtag
     3601 tcatttaagt tttgatacct catttctgtc aggtagtacc attattttgc gattctctac
     3661 ctttatgatt ctcagaacgt cagattgaca caaataattt ctctttgtta acttaacgat
     3721 aacataagca taacatattt tctatctcag aacggttact tttgtgctat agataggaac
     3781 aaaaataagg tttaaatttt atgaatatgc tattaccgga cgaatggata gagaacagta
     3841 ttgaaacata catctatcag cacacaacaa aatcacagat aatctattgg attgtcttat
     3901 ttgcagttac agtcacatta gtggcacttc catttatcta tgtagatatc tccgtacagg
     3961 ggagtggagt agtaagaccg gtagcggaaa aagcggaaat aacttcttcc attacagaaa
     4021 ttgtagattc ggtttttgta aaggaaggag agcaggttaa caagggtgac gtgatactaa
     4081 gattcagaac caatagttct gattataaaa tcaattatca gaccagccga ctgaatgatt
     4141 gtagtgcaca gcttgccgac cttgcttatc tggcagaggg taattgtccg aaactcttca
     4201 gttctccggt aagacaacag gaatatgcct attttatccg taagaaacag gaactggaaa
     4261 caggattggc acaagcggaa aaggaatatc ttagaaataa aactttgttt gaaaagaaag
     4321 ttatctctga ggaggaatac gacagttact atttcaaata caaaagccaa caaaatgaat
     4381 tggcatcgct ggtacaaagc cagataagta catggcaggc agaccagaat acatacagga
     4441 atacatacaa cgaaatgagt accaacctga agcaggaaat aaaagataag gatatgtata
     4501 ttgtccgtag tccggtagat ggaactgttg accagttctc tggagtatat cgtggcagca
     4561 gcattcaggc aggacagtct ttagctgtca taagccccga ctcaacacta tgtattgagg
     4621 tatatgtcac accaagaaat atcggattca tgaatattgg catgcctgta aatgtgcagg
     4681 tggaatcctt caattacaac gaatggggga caataccggg aagagtgaaa gatatatcat
     4741 cagactttct gacagacagt cagggaaatt ccttctacaa ggtgaaatgt gaaatggagc
     4801 gcgacttcct tcaacttaag aacgggagga taggaaagct gaaaaaaggg atgacggtaa
     4861 atgctcattt tatggtaaca agacggtcac tgttcgacct gctttatcag aagatggacg
     4921 gatgggtaaa tccgaagcag tatgaaaatg aaacgatggt agctaaactg aattgattgt
     4981 gaagatagaa taaaagaatt atgtatagaa aaggaatcaa aattaagcag catgacatta
     5041 ctgactgcgg tgctgcatgt cttgcttctg tatgtgcaca ttatgggctt caattccctg
     5101 tggcccgcat ccgccagtat gcctttactg accaaaaggg aactaacgta ttggggatga
     5161 ttgaagcagc aaaccgtctt ggactttctg caaaaggtgt aagagcacag tttgaagctc
     5221 tatccatcgt accgaaacca acaattgcac atgtgattgt gcacgagcat ttgcagcact
     5281 ttattgtcct gtataaagta gaaaaggaac acattaccta tatggatccc ggtgacggta
     5341 aaatgcataa ggttacgaat gctgaattcc agaaaatgtg gacaggtgta cttgttctga
     5401 tggaaccgga ggagaccttt aaaaagggaa atatgaaaac gagcatgaca aggaaatttt
     5461 tctcactgct ggctccacat aagagtgtca tgatgcaggc tgtattcggg gcgttaatat
     5521 acagtatatt aggactttct acttctgtat atgtaggtaa gattactgat tatgtcctgg
     5581 tagacggaaa tatcaacctg cttaacctta tgggaattgt gatgattatt attctgatac
     5641 ttcgtacttt catagggtca atgaaaagca ttctggcatt gaagaccggg caacgaatag
     5701 atgcagctct tattctcggt tactataagc atttgctgac attgccacaa cagtttttcg
     5761 ataccatgcg tgtgggagaa atcatttcgc gtgtgaacga tgcggtgaag ataagaaact
     5821 tcatcaacaa tgtatctctg gatctgctag taaacatgat gattctgtta ttctcggtag
     5881 gtctgatgtt cgtgtattcg tggaaacttg ccttggtgac attggcatcc gcgccattat
     5941 ttttgctcat tttctgggct ttcaataagc tgaacagaaa atatcaacgc agcatcatgg
     6001 agagcagtgc agatctggag tctcagttgg ttgaatctat aaattccatt tcgacaatca
     6061 aacgtttcgg tatagaagac tttgcgaatt tgaaaacaga aatacgtttt gtacacctct
     6121 tgaagaatac ctatcgcagc atttatgggg caattatggc tcagggaggt atccagtttg
     6181 tatcaaccgc aataacaatt gctgtgctat ggatgggaag tgttctggtc atagacaagg
     6241 agcttacacc aggtacactg atggtattct attcgcttat cagttatgtc atatcaccga
     6301 tagggtcatt gatttcatcc aatcagacaa tacaggatgc gctgattgca gcagaccgcc
     6361 tttttcagat tatggatctt gagcgtgaac aggatgacag ccaaaaaata gaactcagaa
     6421 aggatatgat cggggatatt gtgtttgaga atgtatcgtt ccgatatggc tcccgtaaag
     6481 aggtatttaa cggactcaac ctgaagatag ataaaggaaa gaccactgca gtcatcggtg
     6541 agagtgggtc cggtaaaact acactcatat cattgcttca acatatttat ccgattcaaa
     6601 gtggtcagat acgtatcggt ggatatgata tttctcaaat aagcaataag agccttcgta
     6661 gtcttgttgg tactgtacca cagcaaattg agctttttgc cggtactatt atagagaata
     6721 tagcagtggg tgatctccaa cctgatatga agcgtattgt agatttggta gaacaacttg
     6781 gtttgaagga ctttattgag cgtcttccta atggctacat gacctatata ggagaacatg
     6841 gagcttcttt atctggtggt gaacggcagc gaatagccat agcccgtgcg ctgtataagg
     6901 agccggaaat tctgattttt gatgaagcga cttcttcctt ggactcaata tctgagaagc
     6961 atgtaaagag aacactcgat gcactggcca gttccggaaa gacagtcatt atcattgctc
     7021 atcgtttgag tactgtaaaa aatgcagata tgattgtggt acttgacaat ggtaaagtat
     7081 ccgaaaccgg tacgcataag caattgtttg attccaatgg aatttacaac agattatgga
     7141 atgaacagtt tgatcagttg gattaaaaat aaagaactat tgcaatagta taattataat
     7201 tttatcaatc taaaaattta aaagaatgga aagaacaaat gaaaaaaaaa ttgttgcttt
     7261 atcagaaaag gaaagtcaac aaattgaagg aggtattgtc caatttctcc ttggagcaat
     7321 cattggaggg tttatatatg attgcatttc tgaacctgga cattgtatta atggatttcg
     7381 tgatggtatg aataatggtc ttaaatagtt tttattatga aagatttaac aatgacagat
     7441 atggtgaaca tacatggtgg ttctacattt tcatactatg ttttctggtt tttaggtaga
     7501 tcatttgtat ctcctgcaga acttgataaa aatggtatga atccagtaca cttatggaac
     7561 taataatcaa caagtcttgg tatttttatt aataatgaaa aagaagatga gtttcttgta
     7621 gccttctctc ggatatttat aaataacatc agggatggta tatacaaact catcttctat
     7681 ttaagtattt gatttttaac aaaacaacct tttgtaagaa atgcttacct tactggtaag
     7741 tattataaaa gaattgtaaa aaatatcatg aagattcaaa tatgaataag aaactttttt
     7801 tatatggtat attaattgcc gcagtaggac taatactatc acatacatat agaccttaca
     7861 tatatagtca caatcttttt gattttcatt tagcagatgt tattggtagt atcgtgtgtg
     7921 tgccttcatc agttttattt ttttatggga tggatcctag atattctgtg aaaaaatata
     7981 ctgtttacgc tacaatagta tatataagct atgagttgtt ggggcttttc aatatacatg
     8041 gtacctttga tatatatgat attattgcaa ttattatcag tgctttttgt ttttatcgaa
     8101 tttatatcag gttaagtaaa aaaactcatt gaatagaatg attggatgaa actgtatatc
     8161 gcatttccag tgtatttgct gaatgtatca gggctcagga tccatgtctg ataattctgc
     8221 tcgactgggc tgatggcttg ttgcctgaag gtaaggtcaa ggaaccgttc tctaaaattg
     8281 agaagcccgt aaattcggga gaaaggggag ggctgtctag ttgccgacaa tgaaagttct
     8341 gttgttgctc tctgttaacc tgctgataac atttcgataa ctttaatctt ctttctgcct
     8401 atatatattt gtagtgaata aaaaattatt aaagatgaaa agattgatat ttatactggt
     8461 tattgtcgga ttgttttcct gttctggata tgcacaagaa aaaaaatgga ccctttcgga
     8521 atgtattgat tatgcggtga cacacaacat agaggtaaga caaagtgtca atcagattca
     8581 aaatctgaaa gtagaaaaga atacgttaag aaacagcttt ctaccgaatc tgaaagcagg
     8641 cgcttcgcat aactttacat ttggtcgttc tctaaaccag agtaatacat atgagaacag
     8701 taacatacag aactcttctt tctctgtaag cactgaaata cctgttttta tgggatttaa
     8761 acgtacagtt gctgtaacac agaataaatt tgatttactt gcagctgaag caaaaaagga
     8821 acttataaaa aacaatctgt tgataaatgt ggcaggagca tattttcaga tattacttaa
     8881 taaagaaata tataatatag cgcttgcgca gatacagctt accaaagagc aggaggtctg
     8941 tacaaagata ttgattgata atgggaaagc acccgaatca caactttatg atgtccgtgc
     9001 tcaattggcg gatgatgaac ttgctgcaac agaagcacga aattcattaa ggctttctta
     9061 ccttgacttg gcacaactta tggaattaga tgaatatgag gaatttgata ttgattccat
     9121 agatggggat gttgctattg ctgatacttt gaacctgatg aatatttatc agtcagcttt
     9181 gacatgcatg ccgcagatac ttcaggcatt ttatgctttg caaagtaaga caaaaggcat
     9241 aaagatagcc cagtccggat tttatcctac tatatctttt gtagcaggga tgagtacaaa
     9301 ttattataat aatacttctg ctctatatga gaatttcagg aaacagttta ataaccatat
     9361 gcagaaaagt ctgtgtctaa cggttagtat acctcttttc gaccggtttt cagtgagaaa
     9421 taaagtacgg tcagcacgta tagaagaaaa taatgcaaga ttgtccttgg aaaatgagaa
     9481 gaaacaacta tataaagata tagaacaggc ttatacagct gtaatttctg catatgaaaa
     9541 ataccgttct acaacaaaag cggtaatggc caataaagaa gcacacagat acgctttaga
     9601 aaaatatgca gcaggaaagt caactgtatt tgaatataat gaaatcaaga tgaaacttgc
     9661 tgatgcactt tcacaacagt ttcaggcaaa atatacttat ctgctgaaag atcgtatcct
     9721 ggccttttat tcatatttta cattaaccga ttaatacaga taatcatgta ttcgataaaa
     9781 ttagacttga tattgtctta ggtatacaaa attaatttta tacatatgag tatttcacaa
     9841 ataaggttgt accgacagag gcaaacgctc tgttggtaca atagaaaagt gttatcctta
     9901 gtattgtatt ctgcaaataa atattctatg tacatcctcg cttccggtac ttgtaagcat
     9961 tgctactaga cggctcttcc tgcaatgtct ggccttgtgg gggaaacggg atacaactcc
    10021 ccgttgtgct atgaagtctt attgttggaa agtcagtccg gggcaaaaaa tatgggaggt
    10081 gatttccgga cggaatccac ttcccatatt tatgtaaatc ttatactgat ctggttgtta
    10141 atcagtgatg cgtttgttca ggacgatata agaaatcagt cccaaaacaa ccagggccaa
    10201 tgaagtaccc aagatggcat tgttgtttac attgccggtt gcaaagcaaa cgacaagaat
    10261 cactgcaccg ataattacca gtatcactcc caagtttttc aataagcttt tcatgtgtgt
    10321 cttcttttta tggtttattt ttcttggtta caaattaagt tataattctt gtattgagaa
    10381 aattatttcg tgaaaaaaaa cggaaattca atgaaatatc ttcttctcgc agaggttttt
    10441 gtcttttatt ttgtatcttg gtgtagttaa ttcaaatgta tgcctatgaa agtggaacat
    10501 gatgaacaga aaaagaaatt ctttgtgaaa gtcgatggtt atgaggccca tgtggcttat
    10561 gacgtgcacg acggtgcgtg ggatatccgc catacagtgg ttcctaaacc gattggcggt
    10621 cagggtattg cctccatgct ggtaaagcag gtctatgatg aggcccgtgc ccggggaatg
    10681 aaatgcatgg ctacctgctc gtatgcagtg ttgtggttgc aaagacatcc cgagtatgag
    10741 ggaatagtga gcgacgacca tgctcctgac gcttgtgcgt tgtaggcaga acggacggat
    10801 gatacggaaa cggcgtgtat gaaagggaga gcctttatca tacacgccgt tcatttgagg
    10861 tctccgggct gaagatgatt cccggagcga ttttatatcc gaagtctatg ctttataaat
    10921 ctttttcttt ttgatgaaga acagccagcg caacagggaa gcgatgggtg tgtggctgaa
    10981 cgaattgatt tcatcggtcc gttcgtctat cttcttcatc cgttcttccg catctttttc
    11041 cgaaagcatt ccgttgttga ccatctgtct taccgtccgc cgttcgttgc tgagcatcat
    11101 gcggatggac ttgatggtca gtgcatgtcc gtatgccttc gggaaattct tggccagttc
    11161 gttcagtacg gtggtcatcc gctggatatt gtgttcaatc tcattccgca gtgtctgtac
    11221 gatggtctgc tgttcagagg caatccactg tgaggaagcc agctcttcca gcagcttgag
    11281 gctttccttc tggaggatga tgaaacctct tcccaggtca tagaccacgg taatccgttc
    11341 ccggaaatag aaactcatcc agttctggat gtatggcatg ctccgcatgt ggttcagaaa
    11401 atcggtccgc tggcagaact ggaaaatgga gtttcggata tcgagtgcat aatttccgtc
    11461 gtggtcatac agttcgtcca gggagttcat cagccgcagg aacaccgtct tggatatgat
    11521 accctcttca tagatttccc ggcagactgc cttttcgcgg tccagaatac ggagacggat
    11581 ttccggcagc atggcctttg cctgaggcgt tttgcccgga tcggccggaa gttcgctcat
    11641 gtatgaagca accttttccc agttggcccc cgccagggtt tcccgtttct tgagattttc
    11701 caggtacttt tctgaactct cgtgcagcga ctgctcaatg cggtattcca gcagggtacg
    11761 ggccgacggg atatgtgtca gtcccaggcg gttgagcagc cagcgcatgg tggtggcatt
    11821 gatgcagagg gtcagggtaa ccactccggc cgtatagaac aaaatctgac tgcgtatgtc
    11881 ttcaggaatg gcaggcgtat aggataccat cagcgccagc gtcatcgcca gtgcccctct
    11941 cagtccgccc caggtcagaa tcaccgactc tcttcggctc agtccgtagc ccaggcgctt
    12001 catcagcggg aagaacagca tgatcattgc aaaccggatg aggttgaggg cagcataaat
    12061 cagtatcagt atacccagcg ccttccagga gaaatcaatc ttctcggcaa taaccacacc
    12121 caccagaatg aagatcagcg tgttggcaat gtaggtaagc agttcc
//
