LOCUS       gnlProkkaEELMNMAH_100  11703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EELMNMAH_100.
ACCESSION   gnlProkkaEELMNMAH_100
VERSION     gnlProkkaEELMNMAH_100
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:15:23
            Original ID  :: gnl|Prokka|EELMNMAH_100
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11703
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11703
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[329:1703]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      330..1703
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             330..1703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.9e-31,
                     bitscore: 98.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-15, bitscore: 46.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.3e-15, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.5e-20, bitscore:
                     63.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIVLDVYSGSVHAVDDLAYDVIAMYKNATKEQIID
                     EMLSKYADNPEITKEEISDCIDDVKELEEQGKLFTDDKYENLAFDFKKRNTVIKALCLH
                     IAHTCNLNCEYCFASQGKYHGERALMSFEVGKRAIDFLIENSGSRVNLEVDFFGGEPLM
                     NFDVVKQIVAYARSIEKEHNKNFRFTLTTNGMLVDDDVIEFANKECHNVVLSLDGRKEV
                     HDHLRKTVNGKGSYDIIVPKFQEFVKKRGNKGYYVRGTYTHNNTDFTNDIFHMADLGFT
                     ELSMEPVVCAPDDPYALTYDDLPILFEQYEILAKEMLKREKEGRPLTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDEKYKLGDIFNGVSNTKIQDEFKLCNA
                     YARPDCKDCWARLYCSGGCAANAYHATGSITGIYEYGCELFRKRMECAIMMKVAEAEE"
     CDS             1768..2577
                     /locus_tag="ctg100_2"
                     /transl_table=11
                     /translation="MNEKIIMLGTGSAMVTDCYNTCFLLKSENDCLLVDAGGGNGILSA
                     IKKSGIAWNSIKTMFITHSHTDHILGAVWVIRQISALMNSGKYDGNFNIYCHDECVDSI
                     TAICNHTLAPKFLKNINTKIFINEVKDGEKQNAGSIRLTFFDIFSDKTKQFGFKAVFPS
                     GKVLACLGDEPFNEKCRNFVQNCDYLMCEAFCLYSQKDIFKPYEKFHSTALDAGKLAES
                     LFAKNLILYHTEDETLQTRKRTYTSEARTVFNGNIFVPDDFEVIDLK"
     CDS             complement(2569..4482)
                     /locus_tag="ctg100_3"
                     /transl_table=11
                     /translation="MFSTDKSSFNKKDVSDCDYKISLAGNPNVGKSTIFNELTGLRQHT
                     GNWTGKTVEFARGCCKIKDARFCITDLPGCYSLLSFSGEEAVTRECLIQNQNDCVVIVV
                     DCGVIERNLSFALQVLSVTKNAVLCLNLCDEAEKNGIKIDCDELSLNLGIPVVKTCATD
                     KKGLDELKKAIYNVCSGKTKCFRVERNFEGVDILSEKNYKQNIEKLSQIGNKISSDCVK
                     YEKSELNACTRKLDKILTSKTTGIPIMLAMLGILFWITVVGANYPSEWLSNLFGFIKEK
                     LYILFDFLHAPDVVTGLLIDGVYTTLSWVVSVMLPPMAIFFPLFSLVEDSGYLPRIAFN
                     LDRYFSKCGAHGKQSLAMAMGLGCNACGVTGCRIIESPKERLIAILTNNFMPCNGRFPT
                     IIALLLMFFAGTAFTLSSSLEVAALLIGIIVFCVFITLVISKVLSVTILKGEQSGFVLE
                     LPPYRKPQILKTIVRSLLDRTLFVLGRAVAVAAPAGAIIWILANVHISDISLLKYCTDF
                     LDPFGRFIGVDGVIIMAFILGFPANETVVPIIIMSYMASGTLVDYSSYDQLFQLLSMNG
                     WTITTAVCTIILCILHYPCSTTCLTIKKETGSLKWTLVSMALPTAMGIVLCMITAGVMR
                     LF"
     CDS             complement(4498..4734)
                     /locus_tag="ctg100_4"
                     /transl_table=11
                     /translation="MKEKCSLDKLPLGVTGIVYRVNCNENIKNRIFDFGIMENSPVIPL
                     FTSPFGDPSAYLVKNAVVALRNNDCKDIIVTPE"
     CDS             complement(5001..5180)
                     /locus_tag="ctg100_5"
                     /transl_table=11
                     /translation="MCISKGKIKKPSVFGRHNKRNHTDQKSVQIWSAAPLPCPRFAKSE
                     AYGQRPDLWQCQIQ"
     CDS             5202..7091
                     /locus_tag="ctg100_6"
                     /transl_table=11
                     /translation="MNKSFKKILSIVLSVMMISSLMTVSLSVSAVEDGKVRVIVRNDTY
                     SVENGAPWDGVLVDEWVSINNDTTMISAVVDALNNHSYTQEGAESNYISSINGLAAYDG
                     GAMSGWMETLNDWFTNYGFADITVASGNLESGDEIAILYTSNGYGEDIGGTWANNDTTV
                     KSVEITGAELSGEFDPSVTDYTLTIDTPSADVNVVPTATNKNFQTRKYKNQYTPDVKNT
                     DYKRSQTVNVSDGDKIIIGCGDTAWPSMNTSEGGTVYTFTVKYAPSAADTVSNKIDEVA
                     KYLASQDAPTVSSVGGEWTVLGLARAGKITDEITDSYYQNAVKYVEEKGSAKLHNTKST
                     DNSRVILALTAIGKDVTDVASYNLLEPLADMDYVKKQGINGPVFALIALDTGDYEIPQT
                     DAANPTTREKLVQTILDAQVANGGWTFFGSTADPDMTGMAIQALAPYYSTNSDVKEAID
                     KALTAMSNAQNENGGFASWGSVNSESCAQVLVALTSLGIDPTNDERFIKNGNTLIDAMM
                     SFSAENGFGHTDTTYNQMATEQGFYAFVSFDRLVNGKTSLYNMTDRLAENYAVGDVNLD
                     NTVSVIDATLVQKQIVNLEQLSKVSLIKADVNHDGVIDVVDATEIQKIIVKLV"
     CDS             7118..8047
                     /locus_tag="ctg100_7"
                     /transl_table=11
                     /translation="MEKIKKFVKKNQILLIAVCVCIAALTVAFFAGGNRSENKVQTAST
                     ASSLSTTNADTETTSVSATEKTTQNPTDSAKSNKDKKDRKNSEDKKNSKDNSQNSNSSA
                     VEKSDKSEQSSNNSSSDKKKPSSSSNSSSKPNKKNDVQPTTQDKYKTDPVPSGKPKPVE
                     PEEQETKDTNLYCTFTITCSTILDNIDDLDPEKIELVPKDGIILKKQKVQFKEGESVYD
                     VLVKVCKDNNIHMESSWTPMYNSAYIEGINNLYEFDCGSLSGWMYKVNEWFPNYGCSRY
                     VLKNGDDVVWCYTCNLGYDVGGGYATGE"
     CDS             8131..8940
                     /locus_tag="ctg100_8"
                     /transl_table=11
                     /translation="MNPVCLAVSFLCALVTALYLNGKKAVRLSLVFLLPMILLIVLVNP
                     VFNHEGMTILTYFPWDNPLTLESIVYGIASAFLLSSTVLWFSSFNAVITSDKVVFLFGR
                     IMPSLSLVISMALRFVPRFSAQMKLVRNAQHTIGRDIDEGTLFQRIRNAVKILSIMITW
                     SLENAIETADSMKSRGHGLKGRTSYSLYKFDKRDAFMLCTILFTGLVLMILLFTNAIKF
                     RYYPSIKGDLFTVQSVIFYIFYTFLMLIPLSVNIGEGIKWKHMQSRI"
     CDS             8913..11573
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 172.9; E-value:
                     1.5e-52)"
                     /gene_kind="transport"
                     /locus_tag="ctg100_9"
                     /transl_table=11
                     /translation="METYAIKNLSFRYPETGIDVLKDITFTVNEGEFITVCGPSGCGKS
                     TLLRHLKPDLSPHGVLSGEIFFEEKPISDLSHREQSSKIGFVMQSPENQIVTDKVWHEL
                     AFGLESLGYDNNTIRKRVAETASFFGIQNYFEKSVLELSGGQKQILNLASIMAMQPSVL
                     ILDEPTSQLDPIAASEFLHCVSRINHELGTTVIITEHRLDEVLPLSDRVLVIENNGISA
                     FDSPQKVGKILKEKDSKTFLSMPAPMQIWQAVTENDNTDCPVTVPSGKKWLSEYAQNHK
                     MYELKPENIQKHSDKEAVSLNDIWFRYEKSGTDVLKGLSLKIYQGEFAAILGGNGMGKS
                     TALSIICSLNKPYRGKVEISPLNKNSFDTLVAVLPQNPQTLFLKKTVLEDLYEVFDGRK
                     ISKEEKERRVTAAVKLCRLENLCNRHPYDLSGGEQQRAALAKILLIRPQILLLDEPTKG
                     LDAEFKIEFAQIIYDLNKAGITVLMVSHDVEFCAVYPSRCLMFFNGEVVSEGTPRTFFS
                     SNSFYSTSASRMSKGIIDNAVSSNDVIYACTGQNRDIQINRNTPDIDLFKNDTENIPPK
                     KNNAENKKLSVFKKIFGFFGAVLFILGLIINLEYIPNFSAKTLPTWFNWGIIGVSVALL
                     MIAFGTKSKRPIDLPRKSSKLSKRTVSMAIMVLLAIPVTIFVGMTYLQDQKYLFISLLV
                     MIECMIPFFLVFEGRHPKVRELVIISVLCAIAVAGRLAFTMLPQFKPVVAIVIISGVAF
                     GGESGFLVGAVSMLVSNLMFGQGPWTPWQMFAAGIIGFIGGILFKKGLLGRTRTSLCIY
                     GFIATMVIYGGLMNLYSALTSHSAFNLNMLITFYVQGFPMDIVHAVSTVIFLFFGAEPM
                     LEKLDRIKVKYGLIE"
ORIGIN
        1 gacggacaac ataagcgtag ttaaaaaaga ttgacaaatc aatggctgtg tgataatatt
       61 aaactaacaa aatctaacaa ggagtttgat ttattatgaa gagaattaaa actatcgaaa
      121 ctcgtgacct caagaagagc gttaagacag gcggttgcgg cgagtgccag acttcatgtc
      181 agtcagcgtg taagacatct tgcggcgttg ctaaccagca gtgcgaaaag tgcatgagcg
      241 agaaataatt ctattttaat ttgattatta aggattatcg ccgttttccc aaagggttaa
      301 cggctttcct tttgtctaac ggagatatta tgattcatca gtataaactt aacggataca
      361 acatagttct tgatgtttac agcggcagtg tacacgcagt cgatgacctt gcttatgatg
      421 ttattgcaat gtacaaaaac gcaacaaaag aacagataat cgacgaaatg ctttcaaaat
      481 atgcagacaa tcctgagatt acaaaagaag aaatctctga ctgcattgat gatgtaaaag
      541 agcttgagga gcagggaaag ctctttacag acgacaagta cgaaaacctt gcatttgact
      601 ttaaaaagag aaacacagta atcaaagcac tttgtctgca cattgctcac acctgtaacc
      661 ttaactgcga atactgcttt gcaagccagg gcaaatacca cggcgagaga gcgctgatga
      721 gctttgaagt gggcaagaga gcaattgact ttctcattga aaattcaggc agcagagtaa
      781 accttgaggt tgacttcttc ggcggagaac ctcttatgaa ctttgacgtt gtaaagcaga
      841 ttgttgccta tgcaagaagc attgaaaagg aacacaacaa aaacttccgt tttacactta
      901 caacaaacgg tatgcttgtt gatgacgatg taattgaatt tgcaaacaag gaatgtcata
      961 atgtagttct cagccttgac ggcagaaaag aagtgcatga ccatcttcgc aaaactgtaa
     1021 acggaaaggg cagttatgac attatcgttc cgaaatttca ggaatttgtc aaaaaaagag
     1081 gcaacaaggg ttactatgta agaggtactt atacacataa taacacagac ttcacaaacg
     1141 atattttcca tatggcggat ttgggattta cagagctttc aatggagccg gttgtatgtg
     1201 ctcccgatga cccatatgca cttacatatg acgatttgcc tatccttttt gaacagtacg
     1261 aaattcttgc aaaggaaatg ctcaagcgtg aaaaagaggg cagaccgctc accttctatc
     1321 attatatgat tgaccttaca ggcggtccgt gcatttataa gagaatctcg ggttgcggtt
     1381 cgggtacaga atatatggct gtaacacctt ggggcgacct ctatccctgt catcaatttg
     1441 taggcgatga aaagtacaag ctcggcgata tctttaacgg tgtttcaaac acgaaaattc
     1501 aggacgaatt taagctttgt aatgcatacg cccgtcccga ctgcaaagac tgctgggcaa
     1561 gactttattg cagcggcggt tgtgccgcaa acgcttatca tgcaacaggc tcaatcacag
     1621 gtatttacga atacggctgt gagcttttca gaaaaagaat ggaatgtgcc attatgatga
     1681 aggttgcaga agcggaagaa taaaattaca ataaaatttt caggcagata catttttctt
     1741 gtatctgcct gtttttcgag gtgctgtatg aacgaaaaaa ttattatgct cggcacagga
     1801 agtgcgatgg ttaccgactg ttataatacc tgttttcttc tgaaatccga aaacgactgt
     1861 cttcttgttg acgcaggcgg cggaaacgga attttatccg caattaagaa atccggaata
     1921 gcttggaaca gcataaagac aatgtttatt actcattctc acaccgacca tatattaggt
     1981 gccgtgtggg taataaggca aataagcgct cttatgaatt caggcaaata tgacggtaat
     2041 tttaatattt actgccacga tgaatgtgtt gattcaatca cggcaatttg caaccacaca
     2101 cttgcaccga aatttctcaa aaatatcaat acaaaaattt tcatcaatga agtaaaagac
     2161 ggtgaaaaac aaaatgccgg cagtatccga ctcactttct ttgatatatt ttcagacaaa
     2221 acaaagcaat tcggattcaa ggctgttttt ccgtcaggaa aagttctcgc ctgtctcggt
     2281 gatgaaccgt tcaatgaaaa atgcagaaat tttgttcaaa actgtgatta tcttatgtgt
     2341 gaagcttttt gtctttacag tcaaaaagat atttttaagc cttacgaaaa attccacagc
     2401 acagcacttg atgccggaaa acttgcagag agtctttttg caaaaaatct tatcctgtat
     2461 cacaccgagg acgaaacact tcaaacacgc aaaagaacat atacttcaga ggcgagaaca
     2521 gtttttaacg gaaatatatt tgttcccgat gattttgaag ttattgactt aaaataatct
     2581 cataacacct gctgtaatca tacaaagtac aattcccatt gcagtaggca aagccataga
     2641 aacaagcgtc catttaaggc tgcctgtttc tttttttatt gtcagacagg tcgttgaaca
     2701 cggataatga agaatgcaaa gaataattgt gcatacagcc gttgtaatcg tccagccgtt
     2761 catactgaga agttgaaaca gctgatcata gcttgaataa tcaacaagag taccgcttgc
     2821 catatatgac ataattataa tcggaacaac ggtttcattc gcaggaaatc caagtataaa
     2881 tgccattatt ataacgccgt caaccccgat aaatctgccg aacggatcta aaaaatcagt
     2941 acaatatttt aaaagtgaaa tatcgcttat atgcacattt gcaagaatcc agattatcgc
     3001 acctgccgga gcagcaaccg caacagccct tcctaaaaca aataaagttc tgtccaacag
     3061 cgaacggaca atagttttta aaatctgcgg ctttctgtac ggcggaagtt caagcacaaa
     3121 tccggactgt tcgcctttca atattgtgac tgaaagtacc ttagatataa caagtgttat
     3181 aaaaacacag aaaactatta ttccaatcaa caatgccgct acctcaagcg aactgctcag
     3241 cgtaaatgcc gtacctgcaa agaacatgag cagtaatgca attattgtgg gaaaccgtcc
     3301 gttacacggc ataaaattat ttgtaagaat tgcaatcagc cgttcctttg gcgactcaat
     3361 gattctgcat cccgtaactc cgcaggcatt acagccaagc cccattgcca tagcaagact
     3421 ttgctttccg tgtgcaccgc actttgaaaa atacctatca agattaaatg caattctcgg
     3481 cagatatccc gaatcctcaa caagcgaaaa caacggaaag aatatagcca taggcggcag
     3541 cattacagat accacccatg acagagttgt ataaactccg tcaatcaaaa gtcccgttac
     3601 aacatcggga gcgtgtaaaa aatcaaaaag aatatacagt ttctctttta taaagccaaa
     3661 caaattgctt aaccattcgc tcggataatt tgcaccgaca actgttatcc agaacaatat
     3721 accaagcatt gcaagcataa tcggtattcc cgtggttttg cttgtaagta ttttatcaag
     3781 ctttcttgta caagcattta actctgattt ttcatatttt acgcagtcac ttgaaatttt
     3841 gttaccaatt tgcgaaagct tttcaatatt ctgtttgtag tttttttcgg atagtatatc
     3901 aacaccttca aaatttcttt ctaccctaaa acattttgtc tttccgctgc atacattata
     3961 gatcgctttt tttaactcat ccaaaccttt tttgtctgtt gcacaggttt tcacaacagg
     4021 tattccaagg tttagcgata actcgtcgca gtcgattttt ataccgtttt tttcagcctc
     4081 atcacaaaga ttaagacaaa gaacagcatt ctttgtgaca gataacacct gcaatgcaaa
     4141 tgaaagattt ctttcaataa ctccgcagtc aacaactatt acaacgcagt cattttgatt
     4201 ttgtataaga cactccctgg ttaccgcctc ttcgcccgaa aatgaaagca gggaatagca
     4261 tccgggtaag tccgtaatac aaaatcttgc gtctttgatt ttgcaacaac ctctggcaaa
     4321 ctcaactgtt ttacccgtcc agtttcccgt gtgctgtctt aatcccgtca gttcgttaaa
     4381 aattgtactc ttgcctacat taggattacc ggcaagtgaa attttgtaat cgcaatccga
     4441 tacatccttt ttattaaaag atgatttatc cgtagaaaac aataaaaaag cctcctttta
     4501 ttcaggagta acaatgatat ctttgcaatc gttatttctc agtgccacaa cggcattttt
     4561 aacaagatac gcagacggat caccgaacgg acttgtaaac aaggggataa caggactgtt
     4621 ctccataata ccaaaatcaa atattctgtt tttgatattt tcattacagt tcacacgata
     4681 gacaatcccc gtaactccaa gcggtaactt gtcaagcgaa catttttctt tcatctgatt
     4741 caccgatttc aactttttat taacagcata ttcaattcat acaactgagt tacacaaaaa
     4801 gccggccata aacaaaactt atatcgtacc cgaataaact ctgatatcag aaaaatttta
     4861 aggaattgac acgactataa acaggtgtta taattaaata cagatttcaa atgtatataa
     4921 cttaatatgg gtttacggtt caaaatgcat cttgcagagt agataacaga gaattcggtg
     4981 agagtccgaa gcaacagtca ttactgtatt tggcattgcc ataagtcagg tcgctgtccg
     5041 tatgcctcgg attttgcaaa tcttggacag ggaagaggtg cagccgacca tatctgtaca
     5101 gacttttggt ctgtatggtt tcgtttgttg tgccttccaa aaacggaggg cttttttatt
     5161 ttgcctttcg atatacacaa tacaatatgg aggaaaacac tatgaacaaa tcttttaaaa
     5221 aaatcctctc aattgtactt tctgtaatga tgatttcgtc acttatgacg gtttcacttt
     5281 cagtaagcgc agttgaagac ggaaaagtaa gagtaattgt cagaaatgat acatactcag
     5341 tagaaaacgg cgctccgtgg gacggcgttc tcgttgatga gtgggtaagc attaataatg
     5401 acactactat gatatcagcg gttgttgacg cactcaacaa tcacagctac acacaggagg
     5461 gtgctgagag caattacatc tcatcaataa acggtcttgc tgcatatgac ggcggtgcaa
     5521 tgagcggttg gatggaaaca ctcaacgatt ggtttacaaa ctacggtttc gctgatatta
     5581 ccgttgcaag cggcaacctt gagagcggtg acgaaatcgc tattctgtat acttcaaacg
     5641 gttacggcga ggatatcggc ggtacatggg caaataacga tacaaccgtt aaatcggttg
     5701 aaatcacagg tgccgagctt tcaggcgaat ttgatccgtc agttacagac tacacactca
     5761 caatcgatac accgtcagct gatgtaaatg tagttcctac tgcaactaac aaaaacttcc
     5821 agacaagaaa gtataaaaac caatatactc ctgatgttaa aaacacagat tacaagagaa
     5881 gtcagactgt taatgtttct gacggtgaca aaattatcat aggttgcggt gatactgcat
     5941 ggccgtcaat gaacacaagt gaaggcggta ctgtatatac attcacagtg aaatatgctc
     6001 cttccgcagc tgacacagtt tcaaacaaga ttgacgaggt tgcaaaatat cttgcatcac
     6061 aggatgcccc cacagtttct tcagtaggcg gcgagtggac agtcctcggt cttgcaagag
     6121 caggtaaaat cacagacgaa attacagaca gttactatca gaatgcagtt aagtatgttg
     6181 aagaaaaggg ttctgcaaaa cttcacaata ctaaatcaac agacaattca agagtaattc
     6241 ttgcccttac ggcaatcggt aaggatgtta cggatgttgc atcatataac cttcttgaac
     6301 cgcttgcaga tatggattat gttaagaagc agggtatcaa cggtcctgtc tttgcactca
     6361 ttgcacttga tacgggcgat tatgaaattc cgcagactga cgccgcaaat cccacaacga
     6421 gagaaaagct cgtacagaca attcttgatg cacaggtagc aaacggtggc tggacatttt
     6481 ttggttcaac tgcagatcct gatatgacag gtatggcaat tcaggcactt gctccttact
     6541 actcaacaaa cagcgatgtt aaagaggcaa ttgataaagc actcacagca atgtcaaacg
     6601 cacagaatga aaacggcgga tttgcatcat ggggttctgt aaacagcgaa agctgtgcac
     6661 aggtactcgt tgcacttaca agccttggaa ttgatcctac aaatgatgaa agattcatca
     6721 aaaacggcaa cacactcatc gatgctatga tgagtttctc cgctgaaaac ggatttggtc
     6781 atacagacac aacatacaat cagatggcaa ctgaacaggg tttctatgct tttgtttcat
     6841 ttgaccgtct tgtaaacggc aaaacttcac tctacaatat gactgaccga cttgcagaaa
     6901 attatgccgt aggtgacgtt aatcttgaca acacagtttc tgtaattgac gcaacacttg
     6961 ttcagaagca gattgtaaac cttgaacagc tttcaaaggt ttcacttatc aaagctgatg
     7021 taaatcatga cggtgttatc gatgttgttg atgcaacaga aattcagaaa atcatcgtta
     7081 agctcgtttg attaaagttc ataagtaaaa attggttatg gaaaagataa aaaagtttgt
     7141 taaaaaaaat caaatacttt taattgcggt gtgcgtttgt attgccgcac ttacagtagc
     7201 attttttgca ggcggcaacc gatcggaaaa taaagttcaa actgcatcaa ctgcctcctc
     7261 gctatcgaca acaaatgcag acacagaaac aacttctgtg tctgcaacag agaaaaccac
     7321 tcaaaatcct accgattccg ctaaatcaaa caaagataaa aaggacagaa aaaattccga
     7381 agataaaaag aacagtaagg ataattcgca gaacagtaac agttcagctg ttgaaaaaag
     7441 tgataaatcc gagcagagtt caaacaacag ttcttcggat aagaaaaaac cgtcttcttc
     7501 atcaaacagt tcttcaaaac cgaacaaaaa gaatgatgtt cagccaacaa cgcaggacaa
     7561 gtacaaaacc gatcccgtac cgtcgggaaa gccaaagccg gttgaaccgg aagaacagga
     7621 aacaaaagat acaaatcttt attgtacctt tacaatcacc tgttcaacaa ttcttgacaa
     7681 tatagatgac cttgatcccg aaaaaattga actcgttcca aaggacggta taatcctcaa
     7741 aaaacagaaa gttcaattca aagagggcga atctgtatat gatgtccttg taaaagtttg
     7801 taaggacaac aatattcata tggaatcgag ctggactcct atgtataatt ccgcttatat
     7861 tgaaggaatt aacaacctct acgaatttga ctgcggttct ctttcgggct ggatgtacaa
     7921 agtcaatgaa tggtttccaa actacggctg ttcacgatat gtactcaaga acggcgacga
     7981 tgtggtctgg tgctacactt gtaacttagg ctatgatgtc ggcggaggat acgcaacagg
     8041 agaataatga tgaaggatac tttttcaaat atgcacccct ttatcaattt tatatttttt
     8101 gcacttacaa tagggttcac gatgtttatc atgaaccctg tttgtcttgc tgtaagtttt
     8161 ttatgtgcgc ttgtaaccgc tttatacctt aacggcaaaa aagctgtgag attgtcactt
     8221 gtttttcttt tacctatgat actcttgata gttctcgtaa atcctgtttt taatcatgaa
     8281 ggaatgacta tactcacata ttttccgtgg gataacccac taaccctcga atcaatcgtt
     8341 tacggtattg caagtgcatt tttgctttcg tcaacagttt tatggttttc ttcattcaat
     8401 gcagtaatca cttccgacaa ggtagttttc ctgtttggca gaataatgcc gtcattgagt
     8461 ctggtgattt caatggcatt gcgttttgtt ccaaggtttt cggcacaaat gaaacttgtg
     8521 cgtaatgcac aacacacaat cgggagagat atagatgaag gaacattgtt tcaaagaata
     8581 agaaatgctg taaaaatcct ttcgattatg ataacatggt cacttgaaaa cgcaattgaa
     8641 acagccgatt caatgaaaag cagaggtcac ggtcttaaag gcagaacatc ctattcactt
     8701 tataaatttg acaaaagaga cgcatttatg ctttgcacaa tcctttttac cggattggta
     8761 cttatgattt tgctttttac aaacgcaata aaattcagat actatccgtc aatcaagggc
     8821 gatttgttta cggtgcaaag tgttattttt tatatattct acacattttt aatgttgatt
     8881 ccgctatcgg taaatatagg agaggggata aaatggaaac atatgcaatc aagaatctga
     8941 gttttcgata ccccgaaacc ggtattgatg tacttaaaga tattactttc accgtaaacg
     9001 agggcgagtt tatcacggtc tgcggtccgt caggctgcgg aaaaagcaca cttctcagac
     9061 atctgaaacc cgatctttca ccgcacggtg ttctttcggg agaaatattc tttgaagaaa
     9121 aacctatatc agacctttct cacagggagc aaagcagtaa aatcggcttt gttatgcaat
     9181 cacctgaaaa tcagattgtt accgataagg tatggcacga acttgcattc ggacttgaaa
     9241 gtcttggcta tgacaacaat acaatccgaa aaagagttgc cgaaacagct tcatttttcg
     9301 gaatccaaaa ttattttgaa aaaagtgttc tcgaactttc gggcggacaa aagcaaattt
     9361 taaaccttgc ttcaattatg gcaatgcaac cgtccgttct cattttggat gaaccgacaa
     9421 gccaactcga tccgattgcg gcaagcgaat ttttgcactg cgtttcacgc ataaatcacg
     9481 aactggggac aacggtaata ataacggaac acagacttga tgaggtactt ccgctttcag
     9541 acagggtgct tgtcatcgaa aacaacggaa tttcagcttt tgactctcct caaaaggtcg
     9601 gaaaaattct taaagaaaaa gacagtaaaa catttctttc tatgcctgct ccgatgcaga
     9661 tatggcaggc tgttacagaa aatgacaata ccgactgtcc cgtaactgtt ccaagcggca
     9721 aaaagtggct ttcggaatat gcccaaaatc ataaaatgta tgagctcaaa cccgaaaata
     9781 ttcagaaaca ttctgataaa gaagcagtaa gtcttaatga tatttggttc aggtacgaaa
     9841 agtcgggtac agatgtacta aaaggtcttt cactaaaaat atatcagggg gaatttgcgg
     9901 ctatactcgg cggtaacgga atgggaaaat caaccgcttt gtcaattatc tgttcactta
     9961 acaagccata cagaggcaaa gttgaaatct ctccgcttaa caaaaattct tttgacacgc
    10021 tcgtagcagt attaccccaa aatccgcaga cactgttttt gaaaaaaact gtacttgaag
    10081 atttatacga agtatttgac ggcagaaaaa tcagcaagga ggaaaaagaa agacgggtta
    10141 ccgcagcggt aaagctgtgc agacttgaaa acctctgcaa tcgccatcct tatgatttat
    10201 ccggcggtga acagcagaga gcggctcttg caaaaattct tctcataagg cctcaaattc
    10261 ttctgcttga tgaacctaca aaaggacttg atgccgaatt caagattgag tttgctcaga
    10321 ttatatacga cctcaataaa gccggcataa ccgttctcat ggtaagtcac gatgtagagt
    10381 tctgcgctgt atatccaagc cgctgtctga tgttttttaa cggtgaagtt gtgtcggaag
    10441 gtacaccgag aactttcttt tcgtcaaaca gcttttattc cacctctgca agccgaatgt
    10501 caaaaggcat aatagataac gcagtatcat caaatgatgt catatatgcc tgcacaggtc
    10561 aaaacagaga tattcaaatt aacagaaaca cgcctgatat tgaccttttt aaaaacgaca
    10621 ccgaaaatat tccccccaaa aaaaacaatg ctgaaaacaa aaagctatct gtttttaaaa
    10681 aaatcttcgg attttttggc gcagtacttt tcatactcgg tctgattata aacctggaat
    10741 atattccgaa tttttcagcc aaaactttgc ctacctggtt caactgggga attatcggag
    10801 tatctgttgc gttgcttatg attgctttcg gaacaaaatc aaaacgaccg attgacctgc
    10861 cgagaaaaag ttcaaaactg agtaaaagaa ccgtcagtat ggcaattatg gttttgcttg
    10921 caattcctgt tacaattttt gttggaatga catatcttca ggatcagaaa tatcttttta
    10981 tttcactcct cgttatgatt gagtgtatga ttccgttttt tctcgttttt gaaggcaggc
    11041 acccaaaagt gagagagctt gtcataattt ctgttctatg tgcaatagca gttgcaggac
    11101 gacttgcatt tacaatgttg cctcagttca agcccgttgt ggcaattgtg ataatttcag
    11161 gagtagcatt cggcggtgaa tcgggatttc ttgtcggtgc tgtaagtatg cttgtttcaa
    11221 atcttatgtt cggtcaagga ccttggacgc cgtggcaaat gtttgcggca ggaataatag
    11281 gcttcattgg cggtattctc tttaagaaag gtcttttggg cagaacaagg acttcgctct
    11341 gtatatacgg tttcattgcc acaatggtca tttacggcgg acttatgaac ctttattcgg
    11401 cactcacatc acattccgca tttaatctaa atatgctcat aactttttat gttcagggct
    11461 ttccgatgga tattgttcac gcagtttcga ctgttatatt tctgtttttc ggagcagaac
    11521 ctatgcttga aaagcttgac agaattaaag ttaagtacgg acttatcgaa taaacctaaa
    11581 cagcagataa aatttctgct gtttttttgt gctgtaattc aaaaattttc gacaaaagta
    11641 tagacataat ccgaaaataa tattataatt ttggtgtgtc tgattttatt caaacagtat
    11701 tta
//
