LOCUS       gnlProkkaCAADCJHL_28   12522 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAADCJHL_28.
ACCESSION   gnlProkkaCAADCJHL_28
VERSION     gnlProkkaCAADCJHL_28
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 15:53:48
            Original ID  :: gnl|Prokka|CAADCJHL_28
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 47334
            Orig. end    :: 59856
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12522
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12522
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12522
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(530..1342)
                     /locus_tag="ctg28_44"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             complement(1339..2502)
                     /locus_tag="ctg28_45"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             complement(2592..3161)
                     /locus_tag="ctg28_46"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3221..3757)
                     /locus_tag="ctg28_47"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMLRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3798..5342)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_48"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5535..5759)
                     /locus_tag="ctg28_49"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6430..6546
                     /locus_tag="ctg28_50"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             7008..8519
                     /locus_tag="ctg28_51"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCHTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8593..9660
                     /locus_tag="ctg28_52"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDDK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9698..9982
                     /locus_tag="ctg28_53"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_54"
                     /sec_met_domain="PqqD_RRE (E-value: 1.4e-10, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6e-17, bitscore: 53.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYELRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10449..11837)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_55"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12087..12458)
                     /locus_tag="ctg28_56"
                     /transl_table=11
                     /translation="MVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDFLEKA
                     TWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAPQTEAPATN
                     APATETPAPATETPAPAAE"
ORIGIN
        1 aaagaatcac gatatacagg taatccttcg atattcaata caccgcgtcc gataccttca
       61 aacggttctc ctgctttgcc gataccgagt ccaagatgcg taccttgtat tttgtccgcg
      121 tcaaaaccac cgatcgaatg tcctgtgcga agagacacaa ggttgataag gtctaccaac
      181 gtatcaatct gatataacgg gattccacgc atcaggcggc ggcgtagagc ttcggctgac
      241 gggcggtaac gtccggggtc tttgccacaa cgtttataag cctcacgggt agcaaagata
      301 acgggttgat gtttgatgtc ttccatctgt gttgtggaag tcagttgcct ggtaaaagcg
      361 tcgatttcct gccaaagccc ttcgctgtaa gctgtattct tcactgcagc atacacggcg
      421 gctccggcaa aaaccgggca tgcgtctttt atttctttag atacttttat ttcaaacata
      481 acttatcata aaccaatcat cagcgtcctg cgattacgga cgctaattat tactttctaa
      541 tcattattcc cgacaatgta cgaccggaat ctattcccag tctacgtgcg gagaagaatt
      601 catcatgatg aatataggta cagattccgg ccacttctat ctgttctgca ggcactccga
      661 gattcagtaa ttcaatccgg ttggcttccc acaaatcaat atgatatttg cctgtctcct
      721 tcttcttcat agaaataaga gacatatcga agccgctttc ttcaaaagca tcatacacct
      781 catcacctac ttcaaatgat tcgagcgaaa tgctcggccc gatgcaagct atcacatctt
      841 cgccttgcgt cccgaacatc ttattcaagt gatccatcac attactgaca atatgcttca
      901 ccgttccctt ccatccggca tgaacggcag ccacaacgtg ctgttttttg tcgtacagca
      961 atacaggaac acaatccgcc gtcgtgacac aaacgcaata tcccggcaca ttagttatca
     1021 aggcatccat tcctcgcaga agtagccgtc tcatttctaa tgattcttta aaaaatgatt
     1081 cattgataat cagactggca cagccatgat tctgttcagg aataaataat tcctttatct
     1141 gatgattcat gcactgaaac aaccagctct gattgcgatt gacgttcatg catgagtcgt
     1201 tggtataagg cgaacagttg aaagagccgt aagctccggt gcttatacct tcgtgacgcg
     1261 tagttacaaa atgagctact tcgggatatg cctccagtga cttatatccc ttcaactcgt
     1321 tatgttttgt aagtgaaatc atttttcttc ccaatcttct tcttcgtatt cataatcgat
     1381 atcatcgtca tcgtcgacat cttcctcata ttcataaacg atgtcttcat cttcgcccat
     1441 gtctttgagt tcctgttgca gacgggtcac gtctttcgga cggtgaacga tgtcctctat
     1501 cttattgctt tccttgttca gttcttccca aaggatgtct ttcaacaccg agatacccaa
     1561 accggaaaca gaagatatga atacatgtgg aatgccttcc ggcaatgtag gttcaatctc
     1621 gtccatcaac tcctgatcga gcatatcact cttggtgaca gccaacacac gttgcttgtc
     1681 caacatttca ggattgaagg tacgcagttc gttcagcaag acttcgtatt ctttacgaat
     1741 gtcgtcgctg tctgccggaa ccataaacag cagtaatgaa ttacgctcga tatgacgcaa
     1801 gaaacgcagt cccaaacctt ttccctgact ggcaccttcg ataatacccg gtatgtccgc
     1861 catcacaaag gattttccac cgtgatagga aacgatgccc aagttgggtt cgagcgtagt
     1921 aaacgggtaa tcggcaattt tcggtttggc agccgaaatg gaagaaagca aagttgactt
     1981 tcccgcattc gggaaaccta ccagaccgac atcggcaagc agtttcagct ccatgataac
     2041 ggtcatttcc tgcatcggct ctcccggctg cgcaaaacgc ggtgcctgac gggtggccgt
     2101 cttaaaatgc cagttaccct gaccgccgcg gccgcctttg agcaagacca cttcctgtcc
     2161 gtcttctgtt acgtcacaaa gatactcccc tgtctcggca ttataaacta ccgttccaca
     2221 gggtacttct attattttat ccgcaccgtc ttttccgaag ctacgtcctt tgctccccga
     2281 ttcaccatga ccggccattg cgtgacggtc atacttcaag tgcagcaatg tccagtaatt
     2341 acggttaccg cgcaagatga tatgacctcc tcttccacca tcgcccccat caggacctcc
     2401 gttaggacaa tatttctcgc gcctcatgtg cgtagagcct cttccgccct tacccgagcg
     2461 acagtatatc tttacgtaat caacaaaatt cgattcagcc atattttttt taaaagttaa
     2521 agtagtcagt agttagagca gttaattaga acactccggc tactgactta tttatttata
     2581 atattgtatt attacaattt atctactgct tcgcagattt cagcgaagat accttccata
     2641 gtacccaagc cgttgatgtg ttggtatttc ttttcgttct tgtaccagtc gatcagtgga
     2701 gcagtctgtg aatgatatac atgcagacgt ttcttgattg tttcttcgtt atcatcagca
     2761 cgaccggaat ccttgccacg tttaatgaga cgtaccatca gttcttcttc cggaacatcc
     2821 aagtcaacca ttacagaaac gtcctgtcct ctttctgcca acattttctt taatgcttct
     2881 gcttgtgcaa ttgttcttgg gaaaccgtcg aaaattaccc ctttgctatc tttgaagctg
     2941 tcgaatacgc ttgccagaat atcaatcatt aattcatcag gaatcaattg accttggtcg
     3001 atgtaacctt tagctgtttt acccagttct gtgccattct taatttcagc acgcaataca
     3061 tctcctgtcg agatgtgatt gattccatac ttttctacga tacgttcgct ctgtgttcct
     3121 tttcctgaac ccggagcacc gaaaattacg atgttcaaca ttttgttatt tacaatttaa
     3181 cgatttacta tttaccattt aaactggtac ctatttaata ttaatctact actgtataaa
     3241 tatcgggata attacgtccg aaaccatcat aatccagtcc gtaacctacg ataaagtcgt
     3301 tcgggatttc catcgctaca tattcaatgt tgaggtttac cttgagcttt tcaggtttca
     3361 ccaacagaga agcgatatga atagcttcgg gattgcgtgt acctaatgtt tcgagcagtc
     3421 gcagcatcgt cagtcctgtg tctacgatat cttccacgat cacaatggta cgtccggcaa
     3481 tgtcttcatt cagaccgatt acctctttaa tcactccggt ggaagtgatg ccctgataag
     3541 acgccaactt cacaaatgag atttcacaag ggatggtgat gtgcttcagt aaatcagcgg
     3601 taaacatgaa cgaaccgttc aacacactaa ggaaaagcgg attcttacct gccaaatcgc
     3661 ggttgatttc gttcgctacg cgaatcactt ctttctgaat ttcttgttcc ttaatggaaa
     3721 cggtaaacaa tttgtctttt atctgaatgg tatccataac cggtaattta aaaataacct
     3781 tgcaaaaata cgatttttta ttctaccccg tgcatcatct tctgtaattt cttcgagaga
     3841 aggaacagaa tcaacgaagc aacaccggac attacgacga ataccataaa gaaatcatac
     3901 atggtagcaa tctgataacc aaagattgac ttcacttttc cggcttccgg atagagcccg
     3961 ctcaacattc ccgcaaattt attggctgtg gcagtagaca gataccagat tcccatcatc
     4021 agggaggcga aacgcagcgg actcaattta tttaccattg aaagtccgat aggcgacaaa
     4081 gctatttcac ccatggtatg aataaagtaa agtcctgtca gccaaatcat gctcactttc
     4141 actccgggaa ctgcatcttt cactccgaaa cagatgaaaa gataacctaa agaaaggagt
     4201 aacagaccaa tcgcttgttt ggtaggagaa gcaggttcca tctttcgctt gttcaggaaa
     4261 ccccatacac ccggcatgat atatgccagg acaactacaa acagtggatt gaaggattga
     4321 aaccatgaag ccggcatttc ccaaccgaaa atgtcacgat tcgtctgttc ggatgcgaag
     4381 agagttaaag aagctcccgc ctgttcgtag gctgcccaga agaagatgac aaagaaggct
     4441 actatataga taacgaaaat acggctgcgt tctatttttg tcaatgaacc gtctaacagg
     4501 atcagaacag ggaaaacaat gcaggcggta aaaatgccga tactcaccca atcgccttca
     4561 aatgcatagt taaagaaggc tattaaagca atggtaagaa ttgtgattac aagggtatta
     4621 cgtactttgg tacgtttgtc catcttcggg tgtgagatat ggtcggcctt gtcttctttc
     4681 ttttcacgtt tagcatcggg gataatacca atcggttctc cggaaggaga aaaaagatat
     4741 ttattctttt gagtctcgaa aagaacaacg gtgaacagtg tcatgattcc ggctgcaaga
     4801 aatccccatt taaagtcatg cggatcaccg gtatcaccca gataaccaca aatcaaagga
     4861 gcagcaaaag agcctacatt cactcccata taaaaaatgg tgtatgcagc atccagccgc
     4921 ctgtctccgg gttcgtagag ctgacctacc agagaagaga cagtgggttt gaagcaacca
     4981 ttgcccaaga tcaggaagcc tagtccgcca tacatcatcc agtgggcaag gttcgtatta
     5041 tctaaagtgg aagcactcat aaacatcagg aattgtccga ctgccatcat caccgctccc
     5101 caaaacacgg aacgacgaat tccccaatat ttatcggcaa tgtatccgcc aatcaacggg
     5161 gttaaataaa ctagtccggt atagctgccg tagatggatg ctgccgcttc tttgtcaaac
     5221 aataatgcct gcgtcaggaa aagaataaag atcgcacgca taccgtagta actgaaacgt
     5281 tctgccgtgc ttgtcgcgaa aatcagataa aggcctttcg gatgcccttt caatgcactc
     5341 atgaatttat gtgtttagta gtttatgggg tgcaaaggta cagaaaaagt agattagatg
     5401 cttctcttat caaacagaat aataggggga atagtaaaaa cgagcataaa aaatcctact
     5461 gatccacttc attacttttt agcagtgtaa ataataaagt ggagatccat cttaaatgta
     5521 ggttagctac caccttagcc aaaagtaaat tcgacatttt cgatactggc aaaaagcatt
     5581 ccttctcttt tcctcaaaaa gatcttgtct tctcgggcca gccaaccaat agcgagagct
     5641 acgtcttcaa acgtcaaact taattcacgg cacaaatcga acattgaaag ttcacctttt
     5701 tcatttaaga tgcgccatac tttcccggca ttcaagccaa tttttgtctt ttccatcatg
     5761 caaactttag aagattaaac aatccgttat ttagatttta attcattttc attgtgagca
     5821 ctggaaaatg atgtgatgca cattatctat ctccaaagat aacattttta tcggaaacgg
     5881 caaataatca aaggcttaat aaggggaacc gcattaaaaa tttgtttaag aaggtatggc
     5941 gataaactaa acacaatttc catccgcgcc tctacagaaa aagatttttc atttctcata
     6001 ttctcataaa taagaaacaa gtggcagtaa actaataaga tagactatga gaaatgattt
     6061 aaaaacaggc atttctcata gtttcttcgc aaaataaccc ggattttgct tcatttctca
     6121 tagtgtagtg tgccggaagc tgacattgaa taaataaaac tatgtattcc ttttgcttgc
     6181 ttccatacac agtgtcttag ttccacatat tgtgggaaaa gattccctaa ggcttgggaa
     6241 agtattcccg tattttgtgg gaaagtattc ccgtatattg aaggaaaact ttcccacaat
     6301 atatgggaca atcgagacca atgagcatct tcaagcaaaa agccactatt ttatctaaat
     6361 agtagcttca tttcctgata aaaataaggc aggctgaaag aaaaaaggaa gaacaaatgg
     6421 cttttgacta tgagaaatac cctgaaatac tatgagaata aggtggcttt tgagccaaaa
     6481 tatgggagaa cttatgagaa ataccgtttc gaaaaagtgt ttctcataag atatctattt
     6541 gattagcttt cgtttatcga aaaacaatga gaatatgaga aatgaaatga agaaatcttt
     6601 ggttcttctt caaattccgt gctacttatt tatgttcaat taccttattc atggctattc
     6661 cggagtactt taagatgcat atagtttgga taatttattt gctatttcta atatgccgat
     6721 atccctttat ccatcggcct ttcaatgagc tttactagca cggaatttga ttaagaacca
     6781 aatctttttc aggagaaata aaagtaagtt cataatggtg ctgcattgaa ttattttttg
     6841 gcggagttat tctaacactt aatagttcaa aagcagatat ttctctgacc caaagataga
     6901 actaatgatg aattaaaagt tgcaattatg gttttcttcc cacaacaaac gggaaaagtc
     6961 agaagaatca tgtacatttg taatccgaaa actaaaagaa catcgcaatg aaaatatttc
     7021 caagcagcag tatcaagaaa ttggacgctt ataccattga gaacgaacct attgcatcaa
     7081 tcgatctgat ggaacgtgca gcaaccgtat taacaaaagc catcacagac agatggaata
     7141 cggaaacgcc ggtcactatc tttgccggac cggggaataa tggcggagac gctctcgccg
     7201 tagcccgcat gatggctgaa aaaggatata aaatcgaggt atttctcttc aacacgaaag
     7261 gagaactttc acccgactgc caaaccaata aagaactggt agaaatgatg gaagaagtaa
     7321 aattccacga aatcagtacc caattcgtac ctcccgtcct gacgcccgac catctggtaa
     7381 tcgacggatt attcggttca ggcctgaaca aaccgttaag cggcggattc gctgccgtag
     7441 tgaaatacat caattcctcc cctgctatgg tagtagccat cgacattcct tccggactga
     7501 tgggagaaga aaacacattc aacgtaaaag ctaatattat ccgtgccgac gtaactttca
     7561 gtctgcaact gccgaagctc gcctttcttt tcgcagagaa cacggaattt gtcggagaat
     7621 gggaagtgct ggacatccaa ttaagcgaag acggtattga agagatggaa acgaactacg
     7681 aaatgttgga aatagagcaa atccgttcac tcatcaagcc acgcaaacag tttgcccaca
     7741 aggggaactt cggccatgca ctattgattg ccggttcaaa aggaatggca ggagcctctg
     7801 ttctcgctgc ccgcgcctgc ctccgttcgg gagtagggtt gctgactgtc catgcgccaa
     7861 tgtgcaacaa cgacatcttg cagacctcca tacccgaagc aatcgtagaa accgacatca
     7921 acgaaacctg ttttgccgta cctaccgaca cggacgacta tcaagcagtc ggcatcggcc
     7981 cagggctggg acgaaacgag gaaacggaag ctgctttatt ggagcaactg gaacattgcc
     8041 atactcctgt tgtggtggat gccgacgcac ttaatatcct cgccaaccac cgccatgccc
     8101 ttacccacct gccgaagggt tccatcctca ccccgcatcc gaaagaactg gaacgtctga
     8161 ccggcaaatg ccaggactct tacgaacgtc tgatgaaggc ttgcgaactg gcccgtgccg
     8221 cccatgttca cattatttta aaaggagcct actccgccat catcaccccc gaaggtaaat
     8281 gtttcttcaa cccaaccgga aatccgggaa tggcaaccgg aggtagcggt gacgtactga
     8341 ccggagtaat cctggcgctg cttgcccaag gttatcccac cgaagaagcc gctaaaatcg
     8401 gcacttacat tcacggattg gcgggcgatg tcgctcaaaa gaagcaagga atgatcggaa
     8461 tgatcgcaag cgatattatc acctgtctgc cgacagcatg gcgacttgta agcgaataaa
     8521 agttaagaac ttacagtttt ttcaataact tcattaactt tgttttcaaa accagttaaa
     8581 aaagaaccga atatgaaaaa gttgattata gcagcaggac tactaatgac aacgtccgcc
     8641 tatgcacaaa ccgaagtact gacaggggtt acccgaggaa aagactatgg agtggtttac
     8701 agtcttccca aaacccaaat agaacttgaa ataaaagcca acaaagtcaa ctatactccg
     8761 ggagaattca gcaaatatgc tgatcgttac ctgcgactga ccaacgtctc cgccgaccct
     8821 gaagagtact gggaactagc tagcgtaaaa gtgaaatccg taggtgtgcc caacagcgaa
     8881 actacgtatt tcgtaaaatt gaaggataag acagtagcac cgctcatgga actgacagag
     8941 gatggcattg tgaaaacgat caatgttcct tacagcaata gcagtgtagg caaaaaagct
     9001 gctcccgccc ccgcagtcct ccaaaagaaa gcgaatcctc gcgaattcct gaccgaagag
     9061 attctgatgg ctagttccac cgccaagatg gccgagctgg tggctaaaga aatctataat
     9121 atccgcgaaa gcaaaaatgc cttattgcgc ggacaggctg ataatatgcc ttcagacgga
     9181 gcacagctta aaattatgct cgacaatctg aatgcacagg aagaagccat gacgcaaatg
     9241 ttctccggca cctgcaacaa agaagaaaga acattcactg tccgccttac ccctgacaag
     9301 gaattcaaca atgaagttgc tttccgcttt tcgaagaagt taggtgtagt tgccaacaat
     9361 gatttggcag gaactccgtt ttatatcagt ctgaaagacc tgaaatcggt caagatacca
     9421 caggaagacg ataagaagaa gaaagatttg gatggaatcg cctacaacgt acccggacaa
     9481 gctatggtta cactgactga cggtaaaaag aaactttacg aaggtgagct tcctattacc
     9541 caattcggtg tgatagaata tctggctccg gttttgttca ataagaattc taccatcaaa
     9601 gtttattttg atccgaatac gggaggattg ctcaaagtgg acagagaaga agggaaatag
     9661 aaaaacgaag gaagtgaact tctaaaaaac aaagaatatg gttggtgaag gacatgcatt
     9721 cgacatgata cgccgaataa aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc
     9781 taacgataag ttgaagcatc taaaccgtgc aaacgaacct tatccactac ccaacaccac
     9841 ccccgaagaa atggaacgta tcatccacga ctcggagaaa aagaaagaga aagacagcaa
     9901 ttattttgtt tggggaacgc ttattatcat gggagtcctg atagcaattg ccgtcatact
     9961 ttgggctgta tttatcaaat aaataataat aagttcctat ttatacgact ggtatcacca
    10021 gttttataaa tccatctttc tgcatttgag aaagataagc cgatacacgc aactcgtagc
    10081 cctcttcatt ttgaaagtgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc
    10141 catctatcag ttcccataca gctgtaccgt gttcttccaa tttcacatga agttctttcg
    10201 acattccttt tggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga
    10261 gcacaattgt ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct
    10321 ctaacaggtt gattttctct ttggcagcca tacttcttat tttttatttc agagtattca
    10381 tactgatact cttctgttta caccttgata caaaattcct ttgttacttt aggtattgaa
    10441 tttcctagtt acttttggat attcgcctct tccaaaccgt atcccttctt cttgttctct
    10501 gccttcaaca tcaaagccac aatcagagca agcacaccaa agagagcaaa aatagccatc
    10561 ggcaacgtgt aatcataagt ctgtgcaccg tctactaccg gacctttgca ataagtattc
    10621 aacacccatc cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc
    10681 aatgcatatg cggtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata
    10741 gctgaaggca ccaacgagaa ggcaaatccc aatataatca tgatgatagt agcaaaccac
    10801 catatattca gtataggcag agcaaacatc gtatgcacaa aaataagcat cactgatccg
    10861 attatcatca atgtggctcc cttaccgata cggtcataaa gcgagccgaa caacggagtc
    10921 aggataatcg caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctacg
    10981 ttatacttct gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag
    11041 aacaatacac atagtaatgc aatcagccag aatcctttat tggtaatgat atacacaata
    11101 tctttcatac ggaacggctc ttccggctcc aatccttctg catccaaaga agcatccaac
    11161 ttcttatcat agaaagtata aaggaagaaa gcaatcgtac ccacgcacaa cataatcaga
    11221 caaaacaaaa tcggagcagg aatattggta tgaaatgtgc cactctcatc cgtagatccg
    11281 aaaaagtcgg ccaaaggaac cgtgagcacc attgccagag ttgttccgat acgtgccgta
    11341 gccatttcaa gtcccatagc caatgccatt tccttaccct tgaaccattt cacgataatt
    11401 ttggaaactg tgataccggc aatttccaca cctacaccga agatagcata ccccaatgca
    11461 gccagggtta cctgtgtttt gaatccgaag agcatggcac cttccggaaa agtagtagaa
    11521 atcgcatagt atttcaatcc acaaccaaac accatcaata agcaagctcc cattccggta
    11581 aaacgaactc ccatcttatc caaaatgata ccaccgaaaa tcagcatcaa taggaataca
    11641 ttaaaccacc cgtaagcact tgtgaagaaa ccataatcaa gactgtccca tagtagttct
    11701 ttctcaagca tgggttttag aggagacatt acgtcggtga ggaaatagcc gcatagcata
    11761 gtaaatgcga ccaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt
    11821 ttcaaatgtt ctgtcattgt tatatttaaa aatagtagtt aataatcttc atacgaccaa
    11881 caaaggtagt taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt
    11941 taagtgcgga ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg
    12001 cacttaaata tcaaagaaat gcagcatccg tctgcacctt cccattaatg gttttacccc
    12061 aaagtcttac ctgacaacgg agtgaattac tctgctgcag gagcaggagt ttcagtagcc
    12121 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
    12181 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
    12241 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc
    12301 atgaagatag ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgtacgccc
    12361 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
    12421 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
    12481 atttttagtt attttgaatt agcgttaata atcaatttct cc
//
