LOCUS       c00025_gnlPro..        24857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PGELHKDB_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:39:19
            Original ID  :: gnl|Prokka|PGELHKDB_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 31167
            Orig. end    :: 56024
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24857
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[41167:46024]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="2"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(886..2484)
                     /locus_tag="ctg25_31"
                     /transl_table=11
                     /translation="MKKMKIYMKLKSALVLGLFTLTACTGNYRDFNMNPDNVPDSYLDM
                     DGLRYGSAITSMELDMIPCSDQGANAYQRAQNLTGDIFSGQLCAIGVWNGCSNNTTYNL
                     RFDNWNDVMFNIAFTTIMPAWKRVCTEENREKEPVTYAIAQVLKVAAMHRCTDNYGPLP
                     YFQFGNGAMTTPYDAQDKIYESFFKDLNEAIDILEDFCEKNPDARPLKKYDLVYEGNIT
                     KWAKFANTLKLRLAMRIVYVDPANAQKYAEEAVSTSRGVGVMTENDDNAMLHSANGIVV
                     YHPLRVIWAMYKETCMGSTMESFLKGYSDDRIGKYFHKSTLEGGDYHGARNGIIIDDQT
                     LYQRLSTPNIEASNKVKWMCAAEAYFLRAEGALRKWNMEGDAKGLYETGVRTSFAEWEA
                     NIGSYLTNKDAKPAKYDDPIGNNSYSARTEITPVYDEKASVEENLERILTQKWIALYPE
                     GQEAWTEFRRTGYPKIMPVANNFSNGAVDTEIQIRRVTFPQQEYDGNSAEVQRAISLLG
                     GPDTGGTKLWWDKKK"
     CDS             complement(2502..5807)
                     /locus_tag="ctg25_32"
                     /transl_table=11
                     /translation="MRISLVLLFAVVLQLSAENGYAQKIGVAISMSNASIEQVLNRIEE
                     TSDYVFLYNDKTIQTNRIVSVSNKSGKILDILDEIFRGTNVTYTMVDKQIILSTQKLNV
                     TDQSDNKILLKGLVKDAGGEPLIGVNVKAQGASGTITDINGNFNIQVKIGESIEFSYVG
                     YVPQIVKVTGNQPLNIILQEDNKVLSEVVVTALGIKREAKALTYNVQELKSDAITGVKD
                     ASFVTSLQGKIAGVTINQSANGIGGSTRVVMRGTKSLFGDNNALYVVDGIPLSSMRSEQ
                     PMGSFEVPDGGDSDGISSLNPDDIETMSVLTGAAAAALYGAAGANGVVLITTKKGTEGK
                     LSVSYSNDTQFLMPFVMPKFQNTYGRKKEGVFESWGNKLATPSSYDPKDFFQTGFTETN
                     SLSVTSGTDRNQTYFSASSINAAGIIPNNKYNRYNFTLRNTTELIKDRLTLDMSASYII
                     QNNQNMISQGQAHNPLVPLYLFPPGDDIEKYKTYEHYNAERNFNTQFWPYGNKNLAMQN
                     PWWIVNREFFNNNKQRYMFTGSLNWKITSWMRATGRLRVDNSEDTYTRKISASSDKLFA
                     SDYGNYQKMRTQYKNFYADAILNIDKKFGIWGVNANIGGSVTDEIMGDVTGFEGNLVTV
                     PNLFTVENIDRNDAETNMLGGTGVHYNSQSAFATVQFSYKSALFLDVTGRNDWASTFAF
                     TSNEKKGYFYPSVGLSFVPTEMFDLSKTPISFMKLRASYSEVGNAPKPYVSSLSYKITR
                     GKIEDLPSLPATGLKPERTKAFEVGANIRLFKDKINFDVTYYSSNTYNQFFTLDAAPST
                     GYKEYHVNSGKVKNWGVEAMLGYKEKLGQVNWNSTLTFTMNRNKIKELLSESARNPITN
                     ERVILPYMDIVTMGTYKQRIEEGGSIGDIYVQGLKTDHQGYIYVNPQDGSVQADSENWI
                     KAGNSAPKYNFGWNNTFSYKGFSLGFLIDARLGGICVSATQALMDRFGTSQASADARDN
                     GGVMVNGGKVNTEKYYSVVGGGTTGLLAFYTYSATNVRLREATLGYTFPDQWFRGAVKN
                     VKLSLIGKNLFMFYHKAPFDPELASSTGTYYQGIDFFMQPSLRNVGFSLKFQF"
     CDS             complement(6057..6998)
                     /locus_tag="ctg25_33"
                     /transl_table=11
                     /translation="MILKENMENMNPESLLQKAHALGEDIKEMESIDVLHAYHRTQMKM
                     KANRRQQVYSLIMRCAAFLTLPLLMTSLVLGYLYFHEPELDEKYAEVTAATGSVIRYEL
                     PDHSVVWLNAGSTLRYPTVFREENRNVTLKGEAYFEVQADHKRPFYVNTPSGLSVYVYG
                     TKFNVAAYEDDSNIETVLEKGKVNVITPDRSTIVQLIPGEQLLYDKQSKKLIKNKVDVY
                     EKIAWKEGKLIFRNASLDDIFKRLSRHFNVDIQFNNKSGKEYKYRATFRNETLPQILDY
                     LAKSAALKWKTEEAVQQADDTFTKKKIIVDLY"
     CDS             7332..7895
                     /locus_tag="ctg25_34"
                     /transl_table=11
                     /translation="MNLSFSGHTKELTFKQLYEEYYAPFCLYAKRFIEDKDTREDIVSD
                     VFASLWDKIDTFDLKSETALGYIKMCVKNNCLNFLKHQECEWNYAEVIQKKAPIYEIEP
                     DSVYTLDELYRMLYNTLNKLPENYRTVFIKSFFEGKTHTEIAEEMNLSVKSINRYKQKT
                     MELLRNELKDYMPLLLLLIISGQQ"
     CDS             complement(7866..8972)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_35"
                     /sec_met_domain="AMP-binding (E-value: 9.3e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFLN
                     EWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYIG
                     AMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQTE
                     ILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVEL
                     FLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIEAK
                     LHSLIMVPYVVTCIPDIKLGEAIVLLMEQTEDWDKIERALPGILPSYCCPKQIKIVDRI
                     PQTENGKVNRAACRSLAAKLLLSGNNKQ"
     CDS             complement(8972..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_36"
                     /sec_met_domain="MR_MLE_C (E-value: 1.1e-28, bitscore:
                     92.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSFKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_37"
                     /sec_met_domain="ECH_1 (E-value: 1.3e-81, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(10829..12496)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_38"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-08, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(12516..13628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_39"
                     /sec_met_domain="Chorismate_bind (E-value: 2e-57, bitscore:
                     186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(13625..14857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_40"
                     /sec_met_domain="HBT (E-value: 1.4e-16, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(14942..15304)
                     /locus_tag="ctg25_41"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(15375..17144)
                     /locus_tag="ctg25_42"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTGM
                     TPYEFKKTQESLG"
     CDS             complement(17523..18290)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_43"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.2e-07,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVGVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             complement(18626..19876)
                     /locus_tag="ctg25_44"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFAQMPEIKLGQSISFEEYLNRV
                     AKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLEAVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALESACGIWDICF"
     CDS             complement(19854..22961)
                     /locus_tag="ctg25_45"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVVLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITRFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSITTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPAFYYLVENNVLNKKKNDEKEYTI"
     CDS             complement(22968..24077)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_46"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 3.9e-09,
                     bitscore: 28.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMKRELHTFIIGSVLFFTACGDKQESEQKSGYRIQGDTVYIADP
                     LLLEKIKVSVSELKPYSKKVITSGVVRPIPPRYAYVAPPFAGRVTKSYVRIGQSVRQGT
                     PLFEISSPDFTSAQKEYFQALSSRELAKKDLKRKEDLIRNGVSSQRELEEAQNALLIAD
                     KEFENASAALRVYQVDNLAEMILGQPMIVRSPIPGEVIKDNIVTGQYLKDDTEPIAIVA
                     DLSKVWIAAQVKEKDIRFINEGSNLDIEISALPGTVIKGNVYHVEEEVDEETRSIQVLS
                     ICDNLNGHLKLGMYTTVHFLSVPVRQIQIPEKALLQGEKDSYVFVQIAPLVFVRTSVTV
                     ETTENGIAVISEGLRPGDKIISEGGYYLK"
ORIGIN
        1 ttgacgcgga ttgaaacggg ccattcctaa caatgaaggc atcgttcttc ctttagaatc
       61 ccgatattcc gggtttcctc ccgttgacca cagactttca aagttctcag taaaaatata
      121 ctgctccggt ttccagccat tggcatcagc atcatcaaaa cgaccttgca aatcactatc
      181 tccataagag ttataagcct gcacaattcc ataatcaaat aactgggcta atccctcatt
      241 taagtgaaaa ggaactccgt cgatggtaag cagtttgcct gttcctgaag ccgggcctaa
      301 tttttcgctc agctttctta caaaaatctc catattgtcc atgtgtccag gacctgaaac
      361 caacggtccc actccgccaa atcccggttc atagtccaga tccaagccat cataatcata
      421 tttatcaaca gaatcacata ctgcaagcgc ataggcttca attccttctt tagtaacttc
      481 aaattcttcc ggaatagaat gtgcaaaaat ggtaaagatc actttcatac ctttcactct
      541 ccgaacatat tccatatcag ctttcatttc cggagtaatc ttattataat ctccccaaat
      601 agaaataatg tccatactat ccggcacatt agctaatctt gtggacatag ccggaccggc
      661 agccgaccag ttgccaaacc acccaaaggc aatatagtga tctgtatttc gataagcacg
      721 cagattttca taatatgctt ccggtttttc cggaactgtc tggacaacac gtgcttccat
      781 ttcattctgt tcttcacatg ctataaataa agaacttcct gctagtactg ccagaatata
      841 taaaataaat ttcttcattt gattcacttc tttatgagtt actaattatt ttttcttatc
      901 ccaccatagt ttggttccac ctgtatccgg accacctaat agagaaatgg ctctctgaac
      961 ttcagcacta ttcccatcat attcttgttg cgggaaagta acacgacgaa tctgtatttc
     1021 cgtatcaact gctccattgc tgaaattatt ggccaccggc attatcttgg gataaccagt
     1081 acggcggaac tcagtccatg cttcttgtcc ttccggatag agggcaatcc atttctgcgt
     1141 caagatgcgc tccagatttt cttcaacaga agccttttca tcatagacag gggttatttc
     1201 cgtacgagcc gaataactgt tattgccaat aggatcatca tatttagcag gtttggcatc
     1261 tttattcgtc aagtaactgc ctatgttcgc ttcccattct gcaaatgagg tacgaacacc
     1321 tgtttcatat aatcccttcg catccccttc catattccat tttcgcaaag cgccttctgc
     1381 acgcaggaaa tatgcttcgg cagcacacat ccatttcact ttatttgacg cctcgatatt
     1441 aggagtggac aatctctgat ataatgtctg gtcatcaata ataattccat tacgagctcc
     1501 atggtaatca ccaccttcta aagttgattt atgaaagtat ttgccaatac gatcatcact
     1561 gtatccttta agaaatgact ccatggtaga tcccatacac gtttctttat acattgccca
     1621 aatcactctc aaaggatgat acacaacaat accgtttgcc gaatgcaaca ttgcattatc
     1681 atcattttcc gtcataaccc cgacacctct tgatgtactg acagcttctt cagcatactt
     1741 ttgagcatta gctggatcaa catatacaat acgcattgcc agtcttaatt ttaaagtatt
     1801 ggcaaattta gcccacttag taatattacc ttcataaacc aaatcatact tttttaatgg
     1861 acgcgcatcg ggattcttct cacaaaaatc ttccagaata tcaatggctt cattcaaatc
     1921 tttaaagaat gattcatata tcttatcctg agcatcataa ggagtagtca tcgctccatt
     1981 cccaaattga aaatatggca acggaccata attatccgta caacggtgca tggcagcaac
     2041 tttcagcact tgtgctatcg cataagtcac aggttctttt tctctgtttt cttccgtaca
     2101 aacacgcttc caagcaggca ttatagtagt gaaagcaata ttgaacatta catcattcca
     2161 attgtcgaaa cgcaagttat aagttgtatt attagaacaa ccgttccaga caccaatagc
     2221 gcacaactga ccggaaaaga tatctcctgt cagattctga gcacgctgat aagcattagc
     2281 tccctgatca ctgcacggaa tcatatccaa ctccatagaa gtaatagccg agccataacg
     2341 caagccatcc atatctaagt aagaatcagg aacattgtcg ggattcatat taaaatctct
     2401 ataattgccc gtacatgccg ttaatgtgaa aagtcccaat actaatgcgc ttttcaactt
     2461 catatatatt ttcatctttt tcattattct ctattttagt attagaattg gaattttaag
     2521 ctaaaaccaa cattacgcaa actcggttgc ataaaaaagt cgataccctg ataataggtt
     2581 cctgtagaag acgccagttc aggatcaaaa ggagccttat gatagaacat aaacaaattc
     2641 ttaccaatca gagataattt cacattcttc actgcccctc taaaccattg atcgggaaat
     2701 gtgtatccta aagtagcttc cctcaggcga acattggttg cgctatatgt atagaatgct
     2761 aataatccgg tagtaccacc accgactaca gaataatatt tttcagtatt tactttccct
     2821 ccattcacca ttacgccgcc attatcacga gcgtcagcag aagcttgaga agtaccaaaa
     2881 cgatccataa gcgcttgtgt ggcagaaaca caaataccac ctagacgtgc atcgatcagg
     2941 aagccaagtg aaaatccttt atagctaaaa gtattattcc aaccaaaatt atatttggga
     3001 gctgaatttc cggcttttat ccagttttca ctatccgcct gaacagaacc atcctgagga
     3061 tttacatata tatagccttg atgatctgtc ttcaagcctt ggacgtaaat atctccaata
     3121 cttccgcctt cttcaattct ttgtttgtaa gttcccattg tcacgatgtc catataagga
     3181 agaatgactc gctcattcgt gataggatta cgtgccgatt cactcaataa ttctttaatt
     3241 ttattccgat tcatggtgaa ggttaaggtg gaattccagt tcacctgacc taacttttct
     3301 ttatatccca gcatggcttc aacaccccag tttttcactt taccactgtt tacatgatat
     3361 tctttataac ccgtactggg agcagcatcc agagtaaaga actggttata ggtatttgag
     3421 ctataataag taacatcaaa gttaatctta tccttgaata aacggatatt agcacctacc
     3481 tcaaatgcct tggtacgttc cggttttaaa cctgttgccg gaagtgacgg cagatcttct
     3541 attttaccac gggtaatctt ataggataaa gaagacacat agggctttgg agcattacct
     3601 acctcgctat aagaagcacg caatttcatg aatgagatcg gtgttttgct taaatcaaac
     3661 atctccgtcg gcacaaaaga caaacccact gacgggtaaa aatatccttt tttctcatta
     3721 gatgtaaagg caaaagtaga agcccagtcg ttacgtccgg ttacatctaa aaacagagca
     3781 ctcttataac tgaattgcac agttgcaaaa gcggactgcg aattataatg aactcctgtt
     3841 ccacccaaca tatttgtttc cgcatcatta cggtcaatat tttctacagt aaacaagttg
     3901 ggaacagtaa ccaggttacc ttcaaacccg gtaacatcac ccataatttc atctgtcaca
     3961 cttcctccga tattcgcatt tactccccat ataccgaact tcttatctat attcagaata
     4021 gcatccgcat aaaagttctt atattgagta cgcatcttct ggtagttacc ataatccgaa
     4081 gcaaataatt tgtcggaaga tgcactgatc tttcgggtat aggtatcttc actattatca
     4141 acacgcaaac gaccggtcgc tctcatccag ctagttatct tccagttcag actacctgta
     4201 aacatatagc gttgtttatt attattaaag aactcacgat tcacaatcca ccacgggttc
     4261 tgcatagcta aattcttatt cccataaggc cagaattgag tattaaaatt acgttcggca
     4321 ttatagtgct cgtatgtctt atacttctca atatcatcac cgggagggaa taaatacaaa
     4381 ggaaccaacg gattatgagc ttgtccctga gatatcatat tttgattatt ctgaataatg
     4441 taagatgcac tcatatcaag agttaatcta tcttttatga gctcagtcgt atttcttaag
     4501 gtaaaattat aacggttata tttattatta ggaatgatac ctgctgcatt aatagatgaa
     4561 gcggaaaaat aggtctgatt tctatctgtt ccagaagtta cgcttaatga attagtttca
     4621 gtaaaacccg tctgaaagaa atccttcggg tcataagatg aaggggtagc cagtttattt
     4681 ccccagctct caaatacacc ttccttttta cgtccatagg tattttgaaa tttaggcatt
     4741 acgaacggca tcaaaaactg agtatcattt gaataagata cacttaactt tccctcagta
     4801 ccctttttcg tagtaatcaa tacaacacca tttgcaccag ccgctccata caaagctgcc
     4861 gctgcagcac ccgtaagtac agacatggtt tctatatcat ccggattcag actagatata
     4921 ccgtcactat caccgccatc cggcacttca aaagacccca tcggctgctc tgaacgcatg
     4981 gatgataatg gaataccatc tactacatac aaagcattgt tatctccgaa taatgatttt
     5041 gtaccacgca ttactacacg tgtagaacca ccaatgccat tcgcactttg attgatagtc
     5101 acacctgcta ttttaccttg caggctagta acgaaactgg catccttaac tcctgtgatt
     5161 gcatcactct ttaactcctg tacattgtat gtcaatgctt ttgcctctct tttgatacct
     5221 agagcagtca caacaacctc actcagcact ttgttatctt cctgaagaat aatattcaat
     5281 ggttgattac cagtcacctt aactatctgt ggcacatatc ctacgtaaga gaattctata
     5341 gattctccta tcttaacttg aatattaaaa ttaccattaa tatcagtgat agtgcctgaa
     5401 gctccttgtg ctttaacatt cacaccaatc aaaggctctc cgccagcatc ctttacaaga
     5461 cctttcagca gaatcttatt atcactctga tctgtcacat tgagcttctg agttgacaaa
     5521 atgatttgtt tatctaccat tgtataagtg acattggtac cacgaaatat ctcatcaaga
     5581 atatccagaa tcttaccaga cttattactg actgaaacaa tccggtttgt ctgaattgtt
     5641 ttatcattgt acaggaatac ataatcggat gtttcttcta tccggttcag aacttgctct
     5701 atggaagcat tagacatcga gatggcaacc cctatttttt gggcatatcc attctcggca
     5761 gaaagctgca aaactacagc aaaaagtagt accagactga tcctcataat taaaggaagt
     5821 tttagattta aagcatattt aggatataat gcaataaatg aatgattttt tttcatacat
     5881 ttgcggttaa ctaaagttta ttacttaatg aactatggtt tgatttccgg ttagcgtttg
     5941 cgagactctg taccgtgaat ctaaaaattt gggggaagac agctgttgat agcagctttc
     6001 ttcctttttt acattttttg tattatatca taggctactc tcttttaaaa aggttactaa
     6061 tataaatcta ctattatctt tttctttgta aatgtatcat ctgcctgctg tacagcctct
     6121 tccgttttcc acttcaatgc agcagattta gccagataat ccaatatttg tggtaatgtt
     6181 tcattccgga atgtagcccg gtatttatat tccttacctg atttattatt aaactgaata
     6241 tctacattga aatgccttga caaacgctta aaaatatcat ccaatgaggc attgcggaat
     6301 atcagcttgc cttccttcca agcgattttt tcgtagacat ccactttgtt ttttatcaac
     6361 ttcttactct gtttgtcata aagcaactgc tctccaggta ttaactgtac aatagtactc
     6421 cggtcgggag ttatcacgtt tactttacct ttttccagta ctgtttcaat attactgtcg
     6481 tcttcataag cagctacatt aaatttagta ccatatacat acacactaag tccgctggga
     6541 gtatttacat aaaaaggacg tttatgatct gcctgcacct cgaaataagc ttctcctttc
     6601 agagtcacat tacggttttc ctcacgaaaa acagtcggat aacgtaatgt actgccagca
     6661 ttcagccata ctacagaatg atccggaagt tcataacgta tcactgaacc tgtagctgct
     6721 gttacttctg catatttttc atcaagctcc ggttcatgaa aatacaaata tcctaaaact
     6781 aatgaagtca tcaacaatgg caaagtcaaa aatgcagcac accgcattat caggctatac
     6841 acctgttgcc tccgattagc tttcattttc atctgtgtcc ggtgataagc gtgtagcaca
     6901 tcaatggact ccatttcttt aatatcctct cccaatgcat gcgctttctg gagcaatgac
     6961 tcaggattca tattttccat attctctttc aaaatcatat tttataattg caattacact
     7021 tataatacaa acgagtgtat tagaaaagga cagggaaacc gaactttttt attttatttt
     7081 ttggatttga ggtaagcttt actaaaaaaa ggagtctttc atatgcatac accacacatt
     7141 atcaatcatt tattaacgaa caaaaaaaaa tcttcatttc gcatagttcg ttcctcttaa
     7201 aggataacaa tactaatatt ttagactcct tttatatgaa tcagctacaa aaaaagtaag
     7261 gaaatagttt ttatctgact ttcttattat atatttgcga cactaatcaa ctgtattaaa
     7321 tctaaaaaat aatgaactta tctttttcgg gacacactaa agagttaact ttcaagcagc
     7381 tttatgaaga atattatgct cctttctgcc tgtacgcaaa aagattcatt gaagataagg
     7441 atacacgtga agatattgta tcagatgtat tcgcatcact ttgggataaa attgatacat
     7501 tcgacttaaa atcagaaaca gcattgggat atataaagat gtgcgtaaaa aacaactgcc
     7561 tcaatttctt gaaacatcag gagtgtgaat ggaattatgc agaagtcatt caaaaaaagg
     7621 ctcccatcta tgaaattgaa ccggatagtg tatatacatt ggacgaactc tatcgaatgt
     7681 tatataatac actaaataaa cttcccgaaa actaccgtac cgtatttata aaaagttttt
     7741 ttgaggggaa aacacatacg gaaattgcag aggaaatgaa tctcagcgtt aagtccatca
     7801 accgatataa gcaaaaaaca atggagttac tacgtaatga attaaaagac tatatgcctc
     7861 ttttactact gcttattatt tccggacaac aataattttg cagccaatga acgacaagcc
     7921 gcgcgattca cttttccatt ttccgtttgt ggtatccgat ctactatttt aatttgcttt
     7981 ggacaacaat aagaaggcaa aatgccgggt aaagctcttt ctattttatc ccaatcctcc
     8041 gtttgctcca ttaataaaac aatagcttct ccaagtttta tatcaggaat acaagtcact
     8101 acataaggaa ccataattaa tgaatgaagt tttgcttcaa tttcttctgc ctgcacttta
     8161 attcctccgc tattgattac attatccttt cttcccagaa tcgtaaaact accgtccgga
     8221 taaatgcggg caatatcatt tgtctgcaga gtatcatcgc agacaagcgg agcattaatc
     8281 atcaaagtat tttctgaaga caaaaacaac tctacggatg aaaaaggata ataacgatcg
     8341 gatgctgctg cgccattcag acggcgaaga gcgatgtgag aaagggtttc cgtcatcccg
     8401 taagttgaat aaacagcatt ggacagattt ctgatttttt cctctaaagc cttgtcaact
     8461 gctccgcctc ctataattaa aatctccgtt tgctttaatt tctctttctc ttcgggtatc
     8521 tgaaatgtat tatacacctg caaaggcacc atagccgcaa accttaaagg agtgtccaca
     8581 tctgccaatg gatgaccgga agcccgacgt actataagat tcaacccggc aatcaaagaa
     8641 cggacgacta ccatcatcgc cccgatatag cgaaggttca tacacaataa tgccgtttca
     8701 ccctgcttta aatccagaaa ctcacaagtc aggcgtgcac tctgtatcat ctgatctttg
     8761 cgaacaagca attctttagg tgcccccgta gaaccggaag tatgtacagt gatcacagga
     8821 tcatcattaa accattcgtt tagaaaaaga tacaagtccc atatagcaga agggtggttt
     8881 ccctcacctt ctgctacaag gctatgtata tcgcccggag tatattcctt tccctccagc
     8941 aacaaacgct gtttttgtcg gtcgaatatc atcatttaca aaaccacaaa caatcttttc
     9001 tgatttcaag aggcatctct acattatctg taaagagtaa cccggtgcct aacccttgcg
     9061 gcaatggatt ctgaaaagta gcacaccatt gagcgatagc attcagaccg atattagact
     9121 ccagagcaga agttatccac caaccgatat tcagtttctc cgcttctgca atccactcct
     9181 cgccaccggc taatccgcca tgaagagaag gtttgataat aatatattgc ggacggatag
     9241 ccgaaagtaa tctttgcttt tcttcccagg tattatagcc tatcagttcc tcatccaaag
     9301 ctatcggcaa aggagattcg gaagtaagac gtgccatttc ttcccattgt ccggcacgaa
     9361 tgggctgttc tatcgaatgt aagtccagtt cggacaagcg tttcaatttc tccatcgcat
     9421 ctgttggcga gaatgctccg ttggcatcta cacgcaattc tatttcttta aaagaatagt
     9481 gagagcggat atgttggagt aaagccagtt cttcttcaaa gttgatggca ccgatcttca
     9541 actttataca gcggaatccc gcctccatct tcttctctat ctgagcaagc attctattga
     9601 agtcacccat ccagataagc ccgtttatcg gaatacctgc ttccccacgt gagaagggtg
     9661 tatcccacaa agcccagctt ccttcaaaaa agtgacgaat ggctgtctcc aagccaaaaa
     9721 ggatggaagg gtacttgcat agagcttcca tgtccagctt acctccctga ttctctacct
     9781 gccggcagat tttagccagc acttcctcgt aatcgggaag atcatcacag ctaagatttg
     9841 gcagaggagc gcactccccg atccctaccc aattgggaaa ttcgggagca gtaaaatgaa
     9901 gataccagac ttttcgcgtt gtgtatgtgc ctcgtgaagt tccggccggc tgcttgaaat
     9961 gaagcacccg cggaataatg tctattttgc aatccattgt ttaagggaac ttcggatatt
    10021 tcttaaagtt aggtttacgt ttctccagaa atgcattctt tccttcctga gcctcatccg
    10081 tcagatagta aagcaaggtc gcatcccctg ccagctcctg aatacctgcc tggccgtcca
    10141 gttcggcatt caatccggct ttaatcatcc gcaaggccaa cggactgagc agcatcattt
    10201 cttccgccca ttgcacatac tcatcctcca gttgctccaa tggaactact ttattcacca
    10261 atcccatatc caacgcttcc tgcgcattgt atttccggca aaggaaccat atctcacgtg
    10321 ccttcttctg accgacgaca cgagccagat aagaggctcc gaaacctgca tcaaagctac
    10381 ctacgcgagg accggtctgt ccgaagatcg cattctccga agcaatcgat aaatcgcaaa
    10441 ctacatgaag cacgtgtccg ccaccaatgg caaatccatt tacggcagca attaccggtt
    10501 tcggaatgct gcggatttgt ttctgtacat ccagaacact cagacgggga acaccgtcct
    10561 tgccgatata gccgccacgc cctttcacat tctggtcacc gcccgaacag aaagccttgt
    10621 caccagctcc cgtaatcacg atcacatcaa tatccgcttc ttcccggcaa atgcgcaatg
    10681 cgtcactcat ttcagccgtt gtagtcggag taaatgcatt tcgatagcgt tcacggttaa
    10741 tggtgatgcg ggcaatccca ttatagtaat caaagaggat atcttcgtat tctctgatgg
    10801 ttgtccattc tctttgtgtt gacataatct atttttgttt tagttgatga taataatctt
    10861 tcagtatacg tgcatcttta tttttattgc tgaatacttc catcagaacc ggttgttcca
    10921 tggcttccgg ttgtgtgaag gttttcatcg cttcggcaag ctgttcttca ttctctaccc
    10981 gttgataaag gaatccgcgt tcttccgccc atcctttggc agatgtcttg tgaacggctg
    11041 taatatactt gtgcgatgta cccgacatat ccagtccggg taatgtatgg aaaatctccc
    11101 ctcctccgtt attcagcaaa agaatgcgta gattgggacg gacattgatg ttccacaaag
    11161 cattcatatc ataaaagaaa ctaaggtcac ctataactat aaaatttagt ttatccgaac
    11221 cggcggcata tcccactgcc gtggacaacg agccttcgat gccgcttgta ccccgattac
    11281 agcatacctc aatcgtagaa ggaacctggt ataactgagc atagcggata acagaactat
    11341 ttgccagatg caatgcacat gattccggca atgcttttat caaagcaccg atagccgaca
    11401 tttccgaata tccgaactcc ggttcgggaa tggtcttgca ataattctcc catacacggg
    11461 gatactccgg cacgcggtta tccagcaatg gagctatttt ctccagaaac tcaaacgggt
    11521 ccatttcgat gacggtagtc agagaaccgt aaaggtcaac cacttctcca tcagcagaca
    11581 catgccaatg ttctttaggc ggatgctgcc gaagatattt tttcaaccgc ttggaaacca
    11641 catgtccgcc ataagtaatc aataactcgg gagtcatctg gccggttttc tcttcgggca
    11701 tcgcataaag cgccgcatca aaattcttca ctggaatacc gggtactgtc tgattaccga
    11761 tatgctcggt cagccacacg aaatgtttat ataacaattt ggtatgccgt ttctcaaaca
    11821 agtaaatcaa gttcatctgt ccgacaataa tcatccgctt ctgatatctg ttcaagcgtt
    11881 cgatcaggtc attgtaatcc cggtcgtata cattcagccc ctgatagcgc gtaatgacac
    11941 gtacttcggg aagcgactcc accgtaaact ggaacaaagg ttcggatata ggaatattaa
    12001 tatgtaccgg accttttcca tgatggttgg tttccagcaa ggcttcattc accaagcggt
    12061 tacagtacca ttcatcctct tctgtctgaa tctccggaag gtttaccgac ttcttcacca
    12121 atgtctgaaa aacaccgggc tgcggcaatg tctgtcccgc catctgtcca atccaggcag
    12181 caggccgatc ggcagagata acaactaaag gtatattctg ataatacgct tctgccacag
    12241 caggatgaag attgagcaac gctgtaccgg aagtacagca aacggcagca ggatgcccgc
    12301 cattcagcgc aagaccaatc gcaaaataac cggcactccg ttcatccgtc atagcataac
    12361 aagtaaaacc cggatgagta gacagcgtat gcacaatagg tgcattacgg ctaccgggac
    12421 ataacactac tttcgtaatt ccatgcgcct caagcagcgc gaccaactgg agtatatttt
    12481 tcttgtccga atacatattg atagtgatta gcttgttagt gattcatcat tattggagca
    12541 gacacaagaa tacgcctcat ggtctgcaat ttcttttccg tttcctgcca ttcatcattc
    12601 aactctgaag aggctaacaa tccgccaccg gcatacagtg tcaattgctc gtcttcaatg
    12661 tgcatgcaac gcagattcac atacaaatct gtgcgtccct ccggatcgag ccaaccgata
    12721 aaaccggaat aatacttacg atcgtaccct tcattttcca aaatgaaccg gtaggcttct
    12781 tctttaggca gtccgcacac ggcaggagtc ggatgcagga ctttcagaag gtctcccaga
    12841 tttttattat ctttcaaaga gaaatggaaa tcagttttca gatgtgacaa ggcaccggca
    12901 taagccggat aaggtccgct ctctgtggag cgaatgccca gcgaaagaag ctgccgacgg
    12961 atataggacg ccacataatc ctgctcctga cggtttttgt catcccatac ttgcggaagt
    13021 ttaccattct gcaaaggttg agttcctgcc agggcaactg tgttccattc atttttttcg
    13081 cccgacaata taatttcggg ggtacttccc agccacacgc ccgtctgagg agtataacac
    13141 agatagatat aggaatgaat ataacgttga caagctgcac gaaaaacagc tgaaggggaa
    13201 aactccggat tctttccaat agtgagacta cgggaaagca ccagtttatc aaaggtagca
    13261 tcacgcaagg cttcaataaa tgtatgaaaa caggtcgcat acttcccagt acaaagggta
    13321 tgaaaagatt cctccggata actttgcaag tcctgctctt cctctgccac gatttccata
    13381 ggcaacggtt gtccagtcct gtcggactgt atcaacacaa tcggacatga cttatctata
    13441 cggaacggag caatcacaaa tcctctttgt ccattcagtt ctttcaaatc gaaaatcaag
    13501 cggacagctc cgacatcttc tgtcaacaga cgaggatact tctccccggg aacacgataa
    13561 acagcaaagg gctgtttccg ctgaataagt gcatcaatag ttgtcaagtt acttttttcg
    13621 tcaatcatct ttttttcatc acactgttga ccacccgtat agaggacacc agtttattgg
    13681 ttgaagtaaa aacgtccaca ttccatacat gggaggaacg tcctttgtgt acaatcgtcg
    13741 ctactgcacg tactgtatca ccttcgtgcg cagaagatat atgatttccg ctgacctgca
    13801 ttcctaccac aatttcatcc ggctgacaga gaatcatcga gccgagtccg gcaactgttt
    13861 ctcccaatgc aagcgtagct ccaccgtgca aaataccgaa cggctgacgg gtacggtgat
    13921 ctaccggcat cgtcgcctct acacggtctt cgtcggcata tgtatattgg atacccagat
    13981 tacccatcaa tgcgtgacgc gcctgtgcat tcaactggtc caaaggaatc tctgcagcgc
    14041 gaacttccgc tattatcgcc ttttcgacag ccagagccac tccgtcttcc tcattggaag
    14101 ctgtcacata atccgcacag acctttaccg aatcctgcga atgccccatc gccactccca
    14161 gtcctgccag ctgaatcatc gttacatcgc acacaccgtc tcctatagcg atgacttctt
    14221 cacgcttcac atccagttct tccaataaag ctcccaatgt gttggcttta tcaatcgcac
    14281 acggcactac ttccagaaaa taaggttcgg aacggaaaac atccaaagct ccgttcaacc
    14341 gtctcttcca gtgtccttcc agactaacca acgcttcctc gtcatcgctg acaagcatac
    14401 acttacacgg agcaaagtca attgctacag aaaattcctc ttccttgatc actttcaaat
    14461 tattcaagcg agcttcattc tggatatgtt cattctccgg agtgtcagta atgatcgtat
    14521 catcatggta agtgaacagt gcgaaattat tttttcttgc cttcttttcc agataaggca
    14581 acatttccgg attaatcctc cgctcaaaca gtatttctcc gttttgagca ttaattatct
    14641 ggcaaccatt ataagaaagg atataacctc cataatttcc gagttctagg gatttggcta
    14701 aaggcatcag accgtaagtc ggtcggccgg atgccaacac gatacgtact cccatctgct
    14761 gaactttcag caaagcagcc aatgtacgtt tactaatttc ttttgcatca ttgagaagcg
    14821 ttccgtctac atcaagaact aataatttat acttcatgga cacacgattt tgatttagat
    14881 tacaaaggta ggaaattgag tgaacgactg aaagcggaaa gagataaaaa ttactttaat
    14941 ttcactcttt cagatgcatt tccaaataat cacgaaggat tcgggcatga ttataaaccg
    15001 gttctttgga tgcataaagc aaagtgatca ccggatgagg tttgataaga gtcagaaaat
    15061 cggcaacagc ttgagaagct tccagttcct tctgatacat tacgacaaaa tcattccagt
    15121 gacccggaat atcttcatga aaccatctgc gcagtgctgc ggaaggcgtt atatcttttg
    15181 cccagtaatc atatttcaac cattcttttt tgattccacg tggccagagt ttatctacca
    15241 gcacccgata tccgtcggtc tctgaaaagt cttcgtacac tcgctttatc ctaacttgca
    15301 ccatttccgt ttatatttag ttatcataag aataaaccga taaaacggaa aattgtttat
    15361 cgaaaaagcc aaaatcaacc taaggattcc tgcgtttttt taaattcgta aggagtcata
    15421 ccagtctttt tcttgaacat actgtacaga ataggcgtac tattaaatcc ggcttcatca
    15481 gctatcgcac gaatggtata attgggatgt tgcttcaata actgaatcgc atagttaata
    15541 cgaagttcat taatataccc gttgaaatta gttccggtgt tttccttgat catccgggcg
    15601 aaacgcgcat tattcaaatg tacaatctga gccagatcct ctctcgacaa ttccggagac
    15661 agatataact gatcctgaac aacaatacga ttcagttctt tgaaaatttt cttattctca
    15721 tcctcttcct ccctactctc cactacttca tccggagata aatcgtcttt ttcggaaaag
    15781 ccagtttccg gttccaagtc caatggaaca gctatcggat cttccgcatc tccatctatg
    15841 aataattgtt tgttctctac ttttccagcc agtttctcat tgataaactt tgccagcatt
    15901 ttgtttttat atttaacaat aatcgtatga cgccaaatcc gccatagcac aaataaaatg
    15961 agacaagtga cacatcccaa aaaagcaagt gatatgtttc tgattcttaa ctgtaaagtc
    16021 tgttcggcaa tatattcttc ctgctcgtca gctttatgaa tagcatttaa ttccaaagcc
    16081 gcattctgct tatccttgct gttaatacca tcaataatag aaataataga ctcacgtaat
    16141 gctgctactt tttcaaaatc cttcaagcct ttataagctt tcacctcttt ctgaaggata
    16201 ctaatatact gcaagttgac agtatcctgc tcttgcatca atttcttaaa atcctgacat
    16261 tgatcaacga ctttctgata ttgtttagac actagcagat aaggtatcgc ataggttttt
    16321 ccatccggtg tctgtgaatt ctctgttgac aaatattgtt gataatattt ttccgcctga
    16381 tcatactttc cttccagata gcagatatac gacatttttg catacaagta agtatattgc
    16441 agatcaagaa agccttttgt tttttccggt aatttagcta tatctttaag tagcttttcg
    16501 cgcttcaacc caacctccaa tgcttcttta ctacgggaat cattgagcag ataatccatt
    16561 ttcatcccat aaaagtatga aagcatagcc atttccaatt tggaacttgt accttgaagc
    16621 aatttgatag ctttgtcaaa atagtcatat gcctcctctt tgaaagacaa ttgccattta
    16681 ttttcaccaa tgcaaaacaa cagcttactt tcagcccctt tatccttttc tttttgtgct
    16741 agcttgatac catcaagagc atacctcata ctctctttat ggtcactcat aagcactgct
    16801 aattctgcca ggtcgacagt catggtcaac aagtgcttag gatctttctg agaaacggaa
    16861 tccagcaaat aagacttttt ggcatacaaa aaagccagtt tagtcatata catattacga
    16921 taaaccctgc tgcgtaattc atgtataata cgcagaggga tagtcttctt actttcagct
    16981 ccatccaaca aacttaaagc ccgttcaggt tctgccatat aaattcgact tatatactca
    17041 ctggtatata gcgaatcatt ctctatagtt ttgtcggcga aaaggagctg gttaaacaca
    17101 aacaaaaaca aacaaaaaca aataaccgag cgaatacttt tcattataat cccaatgatt
    17161 ttactcccca aaagtaaaac atagtttcat aaaatgcaag aattgaacat atttgaatga
    17221 actaaaataa gaaaagttag tgattataaa agtcaagagc catcaagtct tccccaccaa
    17281 ccacatacaa taaaatacta aaaatcaagc atatgtcaca tacataaaac aaaacatctc
    17341 aacatacaaa taaactgccg attctattaa ggaatctgca taagatcaga gcagcacatg
    17401 aaaaatcgaa ccgaccagtc taaataaaca ccagacaatt attaacccgc cacactcatc
    17461 agagcaaaac agcacaaaaa cagaaaatca aaaaagagaa acacatactg taataagaaa
    17521 gattataatc ccaacgcttt atcaaaccgt tgctccatac atgcactcaa atccgtcgtt
    17581 acaaactttc ctttatagaa aagagaaaag atagtagcag gtgtaggtgc attttgtgct
    17641 tgtgccatcg tttccaatct gactatcttc aatggaatac ctttgttctc agtcacaccc
    17701 actaaagaat tacggacatg aaactctgca aacggacaac gatgtgtata ataaacgact
    17761 acaccttctt tttcctcaca ttctccactt gatactgttc cattgaatga cggatcagga
    17821 gctgccggat ttatcttcaa agccaaaaga ctgaaaccat agggtagttt ttctatcgtc
    17881 tcaaacccct gacgtaataa ccatttcgca tcacccataa aatgaaattt agaggtaccg
    17941 accacagtca ccaagccatc cctaccctgt gctttggcat cctcgacagc agactgtaat
    18001 agtgctttgc catgcccgca tcctttatat tttcctgaaa cccaaaaaca gtttatcatt
    18061 aaatagttag gtgcattaac cggaacccaa gctttttcgg caggcccata ttctataaat
    18121 acttttgcac gttcgtcaag ccgtctgaaa acatagccat tctcaaactc atttttcagc
    18181 catgtctttt tcaactcata gctatccttg catttcttat cggagaaagc acagcaaata
    18241 tgttcttttt cgatattctc tttagtcaga gtgatatact tcgcttccat aatattctgt
    18301 ttattagtat ataaattccg gttgtccatt ttaactacag caaagataca caatcgaaag
    18361 taataaaaca ttgtccagtc tcgtcaaaat gacacagtag tacggattaa agttcggaaa
    18421 acagataagt aaataaacct gagtgacaaa cttatcaaag aacttattga ccactctgtg
    18481 gaagaagtga tcaaaaaact ccctaagaaa aaacaggagg aatatcgcac aatgatttaa
    18541 cataaagcgt gaaaccgctg actggtaacc atacaaatat ccggctttgc tgcaattcac
    18601 aatagtaaag ccggatattt aactgttaaa agcatatatc ccatatacca caagcacttt
    18661 ccaatgctac tagtgaagcg gcatatcctt tcattgtttc cagatactcc tgttgcactt
    18721 cattataagt acgctgggca accagtacat caagaatact cgtttctccc cgtttgtatt
    18781 tatataccat tccgtcgagc accttctgcg agtcttcaag tacaccggct ttatattgag
    18841 ctatcttttt cttttcagcc tcatagttga accaggcctg ggttatctct gcctgtatct
    18901 gcaattccat atctctttcc attatctccg attgggcaat ccgaaacttt gcagctttta
    18961 cagctccttt atttatattc gagaatgtca gaggaacaga tacaccggca gtagcagaac
    19021 gggacggagg aagaaagccg ttccagtttc tttcataaga aacagatact ccgatatcgg
    19081 gtctgcgttc cgctctcgtc agtttatatt cccgggtagt aacttcagta cttttttgag
    19141 caacaagcag gtcgatgcga ttatccagtc ccgctttgac caaatcagac agagcaaagt
    19201 ccctgcttag ctcttcccaa tttcccaaag ggatatgaag cgtatcagca ctcatcccca
    19261 tgtgtttatt caacaaaacc aaagcggaat gataagccgc ctcctgactg taaacagtat
    19321 taagcaaggt gacagcttcc agttttgact gccggacatc attctccgta atctctcccg
    19381 aaacataacg taaactatct gactgactca gctgatacat atactcataa gaacttttct
    19441 gtacttcaag taattcgcgc tgaagaattg cttctagaaa aaggtcggca gcctccgccc
    19501 tcaaatcctg aaagccctgt tgcaggacca gtttctccaa ttctgcctga gtccgcgcca
    19561 acttaatacg tgctcccctt ttatttccca tttctaatga ataggaaact cccaacgaga
    19621 aagtctcatt acctgcttca aattccaact ccggatccgg aaagattttc cgggcaatta
    19681 cttccgcatc agcaatactc acattgagtt tttcggctaa ataactcagg ttctttttcg
    19741 ctacccgatt cagatattct tcgaaagaaa tagactgccc cagctttatt tcaggcattt
    19801 gcgcaaaagc cggaatgagt acggcttcca ccattaacag caagagcact atattatatc
    19861 gtatattctt tttcatcgtt cttcttttta tttaaaacat tgttctcaac cagataatag
    19921 aaagccggaa gcagaaacat agagataagg gttgaaaaca tcaatccata cacaatcact
    19981 gttgccagcg gacgctgtac gtcactaccg attccggttg ccaacgaagc cgggaaaagt
    20041 ccgagtatcg tagtgatcga agtcatcaga ataggtcgga aacgctggcg tgccccttct
    20101 atgaccgatt tccggagttc cattcctccc ctgcgcagcc cattgacctg cgataccatg
    20161 ataattccat tttgtatgga aagcccgaac atcgctataa atcctacggc agaagataca
    20221 ttcagcgtca taccacgcac attaagagca agcatacctc cgaaaagtgc cagaggaaca
    20281 atagccaata ccagtcctgc ctgccggaac ttcccgaacg tgacataaag cagtataaac
    20341 atccctgtca gtgtcagcgg tataatgaca gcaagacgtg tataagcccg tttttgattt
    20401 tcgaaggccc ctccccattt gatggtatat ttattcttgt cataatgtac tttctcattg
    20461 atcgtattct gggcttcatt cagaaaagat gtcaggtcac gaccgcgcaa attcagcttt
    20521 accgtcaaat ggcgtctgtt catttccctg gtaatcgtac tttcgccgac actcaatctg
    20581 acatcggcaa cctgagaaag aggtatcttt gcaccggtgg aagaagtcaa cataagtccg
    20641 gctattttct ccggagtatt ccgcgcttcc tctttatact tacaggtgat gccatactgg
    20701 cggtcaccct gataaagttg tgcgatagct ttacctccga cagccacttc aatcagatcc
    20761 gctacatcgg atacatttaa tccgtaacgg gctatggcat cacgattcat actgatctgt
    20821 aactgtggca agggtggttc ctgatcaata tccagatcaa cagcccctcg cacagttcct
    20881 aatgccctgg ttatttcttc ggcaatacga cgtgtttcac gaaaatcttc gccatatact
    20941 ttcaccacca gttcactatg ggccccggct atcttatcca tcaccccgtc tatcataggt
    21001 tggctaaatc ctactttaaa accgggaagt aacttatatt cttcttccag ttcatgaatc
    21061 aaatcctttt tagtttttcc tttcggccat tcatcataag gcttaatacc gatggacact
    21121 tcaaaatgtg aaggggtgaa cggatcagtt ccgtcgtcat tccttcccgc ctgtaccata
    21181 atataagtta cttcggaata cttcatcgta cgggcacgca aagtatcgga taactcccgt
    21241 gacttttcta cggaaattcc gggtggcaga ttaacctgta accatatcga accttcatct
    21301 agctccggaa ggaagtcttt tcctacgaca acactcaaca cgatccccgc tgtcagaatc
    21361 agtcctgatg gaatgatggc ttttaaggga gcttccagaa atcttgtaat ggtacgaatg
    21421 tatttatcct ttagtctgtc cagccattta ttcttatata ttttatgtgg tttacgatag
    21481 attgcatagg caagtcccgg aatcaataag agcgcaacca acagtgctcc aatcattgca
    21541 tagctcatcg taaatgccat tggagtaaaa agtttgcgtt caacacgttc aaaggcaaac
    21601 agcggaaggt atgccgtaat aatgacaatg gttgagaaaa gaataggccg acccacttct
    21661 ttggcgcgtt gcgccatgct tttttcttcg agatattgtt tgggattatc ctcacgtttc
    21721 ttaaggatcg tttccagcat aacgatagca ccgtccacaa taataccgaa atcaatagca
    21781 ccaagcgaca gaaggttagc cggaatatcc gtcagatgca taagaataaa agcgataagc
    21841 aatgacacag gaatcgttat agataccaat aatgcaccac gccagttgcc tagaaacaga
    21901 ataagcacaa gaaccaccaa agccataccc atcagcaagg tatgggatac ggtactcaaa
    21961 gtagtatcca ccaagttggt acgatccaga aaagtatgta tcctcactcc ttccggcaat
    22021 gtctcattat ttaactcatc aactgccaca tgaatatctt ccagtacttt agacggattc
    22081 tcatgtttca gaaggagtac aattccttcc agactctcag agtagttgcg ggtacggtcc
    22141 gtatatccca gcactccctt tctttcaaga tttccatact tcaaagaacc tatatcattc
    22201 agaaagacag gaactccgga agtagtactc actacaatat gtcccaaatc gtccaaattt
    22261 ccgattaatc caattccccg taccacataa cccaagtcac cacgattcaa cacgcttccc
    22321 cccacattgg cattgttatt ctcaatggct tcaacaacct ggctgagaga taaattatat
    22381 tgttccagtt tggacggatc tacttcaacc tggaactgag tagtgatccc accgaaattg
    22441 gttacatcag ccactcccga cacttccttg atacggggaa taattaccca gttctgaagg
    22501 tcggttaatt cgcgtaatga gtgctggtca ctttctatga tataacggta cacttctcct
    22561 acgggagatg tcagcggatc aagtcccgga acagctccat aaggcagttc tacttcattc
    22621 aatctttcct gtacgcgctg gcggctccag tagtcctctg tcccgtcctt aaagacaatg
    22681 gtaatcattg acagcccgaa tgtactctta ctccgcatga cgtgcatacc gggcagccca
    22741 ttaatagcgc gttccaaagg aatggttatc tgctgttcca cttcctccgc agccagtccg
    22801 ggaacttgag tgaccacctg ggaagtgaca tctgcaatat ccggatatgc ttctatcgaa
    22861 agctgtttcc atgagtaata tccaaagata cacatcatca caaacaggca aagcattacc
    22921 catctttttt gtataattga aagcattaat tccttcttca taatttctta ctttaaataa
    22981 tatcctcctt cactgattat cttatctccg ggacgcaatc cttcgctgat caccgctatt
    23041 ccgttttctg ttgtctccac tgtcaccgac gtccgtacga aaaccaacgg agcaatctgc
    23101 acaaatacat agctatcctt ttcgccctgc agtaacgctt tctccgggat ttgaatttgt
    23161 ctgaccggaa cactcagaaa gtggacagta gtgtacatcc ccagcttcag atgtccgttc
    23221 aaattatcac agatcgaaag tacctgaatg gaccgggttt cctcgtctac ctcctcctct
    23281 acatgataca cattgccttt aataaccgta ccgggcaatg ccgaaatttc aatatccaga
    23341 ttactgcctt catttataaa ccggatatct ttctccttta cctgagccgc aatccatacc
    23401 ttagacaggt cggcaacaat agctatcggt tcggtatcgt ctttcagata ttgccctgtt
    23461 acgatattat cctttatcac ttccccggga ataggagaac gaacaatcat cggttgcccc
    23521 aatatcattt ccgccagatt gtccacctga tatacccgca atgcggcaga ggcgttttca
    23581 aactccttat ctgctatcaa taaagcattc tgggcttctt ccagttctct ttgcgaactg
    23641 acaccattcc ttatcagatc ttctttgcgt ttcaaatctt ttttagcaag ttccctggac
    23701 gaaagtgcct gaaagtattc cttttgtgca gaagtaaagt cgggggaact gatttcaaat
    23761 aaaggtgttc cctgacgtac cgactgtccg atacgcacat aagattttgt gactctccct
    23821 gcaaatggag gagcaacata agcataacgg ggaggaatgg gacgcaccac accggacgtt
    23881 atcaccttct tggaataggg tttcagttca gacactgata ctttgatttt ttcaagtaaa
    23941 agaggatctg caatatagac cgtgtcacct tgtatacgat agccactttt ttgctctgat
    24001 tcctgtttat ccccgcatgc ggtaaaaaac aacacactgc caataataaa tgtgtgtaac
    24061 tctctcttca tcatcataat taaacataag ttaagttagt aaccggattt ccgggcacaa
    24121 agatagacgg ctcccttcgg agagcctgtt agagaatagt tagaatccta ttagaatctt
    24181 attagagtaa ataaagattt cttcttaaaa cagcagtttt gttgttagag agtacgcaca
    24241 aataaggggt tgactaaaaa gccaacccct caacggatga tattccggta tttttatcgt
    24301 aagccgaaaa gttcttattc tttcacacaa cgtatacttt gagcaaaacc ttgatatgac
    24361 aatctgaaat tatgagaatt atatgcagac tcaagcgacc aggctccata acgtattctc
    24421 ctgtcataag gtggattctg caattccgat ctcatataag gaggacctac acttgccgac
    24481 caatagtatc cggtactacc cctactttcc aaagcaccac ttgtgttatt cagacgaccg
    24541 gctgacggaa aaaagacaga tgcattcgtt ccggaatcgg gattaaaata caatactccc
    24601 tgataagcaa cattactatt tcctaatgat acgccatagt ttccattcga agcctctttt
    24661 atcggacgtc tgtcgaaaaa tccgtccgaa taaaatgtat aagttgttcc ttttagttgt
    24721 ttccgggcaa gcatatcttt gtttgctccg taaggatatg tcccaggacc tgtattacca
    24781 gttccaccaa aaggagtagt aaaagctgta gcgtagtctg cacttgaagc cgcatttcct
    24841 gcaaaaggta cattaaa
//
