LOCUS       c00036_gnlPro..        14938 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKOCELHN_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:06:31
            Original ID  :: gnl|Prokka|NKOCELHN_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14938
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14938
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8381:11939](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(8382..11939)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14938
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14938
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             281..3034
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_1"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1e-20, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLTGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGRIAVRLSSLCKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             3062..3394
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(3357..4643)
                     /locus_tag="ctg36_3"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLTLPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFHKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             5117..6343
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKEEREKKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             6340..7170
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.6e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             7198..8058
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNAETIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPKKD"
     CDS             complement(8069..8257)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MIGFVIWIVGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(8382..11939)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_8"
                     /sec_met_domain="PFOR_II (E-value: 5.5e-19, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.3e-83, bitscore: 267.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.8e-32, bitscore: 99.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.2e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.1e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIAADCTPAEVKELFAEWINNMLDADKTKE
                     LAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(11972..13177)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFAYEFQKRGGKVLLID
                     QVFKHPEWSRELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLW
                     KDHKVHKGDKNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGF
                     LY"
     CDS             13357..14511
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGAFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 ctttgttaac cttaaatcta atactatgaa aaacacagta caaagatacg gacttctgtg
       61 aaatctgcaa attatccaag taaaacgcta tgttttataa cattgattaa gtgtttgttt
      121 tacgctttat acttttgtta atactttccg atggtctgaa agaggactgc tttccttctt
      181 tttagaataa taaatagctg aagttagaga actttacagt attatttctt atttttgttc
      241 ttaattggat tacagaaaga actacgaaat gatgagatgg atgaagacga tgagatatct
      301 gaagtggatg ctggtgctgt tttgtttaac cgggatgacg gcttgccggc aggatacacc
      361 ccgttttcgt attggggtgg ctcaatgcag cgatgattca tggcgacata agatgaatga
      421 tgagattctt cgggaagcga tgttttataa tggtgtttcg gtggaaatcc gttcggcagg
      481 ggatgataac actaagcagg cggaagatgt ccattatttt atggacgaag gagtcgatct
      541 gctgattatt tccgctaacg aagctgctcc tatgactccg attgtagaag aagcttatca
      601 gaaaggcatc cccgttattc ttgtagaccg gaagattctt tcggataaat atactgccta
      661 tatcggagcc gataattatg aaatcggtcg ttcggtagga aactatattg cctccagtct
      721 gaaagggaag ggaaatatag tagaactgac aggattgagc ggttcgactc ctgcaatgga
      781 acggcatcag ggatttatgg ctgccatcag taaattcccg gatataaagc tgattgataa
      841 agcggatgct gcttgggaac gtggtccggc agagatagaa atggatagta tgcttcggag
      901 gcatcctaag attgatgctg tgtatgccca taatgatcgt atcgctccgg gtgcctatca
      961 ggcagcaaag atggcagggc gggagaagga aatgattttt gtcggcatag atgccttgcc
     1021 gggtaaggga aacgggctgg agctggttct ggacagtgtg ctggatgcta cctttatcta
     1081 tccgaccaat ggtgataagg tactgcaact ggctatggat attctggaga agaaacccta
     1141 tcccaaagaa acggtgatga ataccgctgt tgtggaccgt accaacgcac acgtcatgca
     1201 gttgcagacc acacacattt ccgaactcga caaaaagatt gaaacgctca acggacgtat
     1261 cggtggctat ctctctcagg tagctacaca acaggtcgtt ttatacggca gtctgattat
     1321 ccttttattg gtagccggct tattattggt cgtttataaa tcactccgct caaagaatcg
     1381 cttgaataaa gaacttttta agcagaagca acaattggaa gagcaacgtg acaaactgga
     1441 agaacagcgt gaccaattga tacaactttc tcatcaactg gaagaagcta ctcatgccaa
     1501 gctggtattc ttcaccaata tttctcacga cttccgtact ccgttgacat tggttgccga
     1561 tccggtagaa catttgttgg cggacaagac actgagcgga gatcagcacc ggatgctcat
     1621 gctgattcag cggaatgtga acattcttct gcgtctggtc aatcagattc tggatttccg
     1681 taaatatgaa aatggcaaga tggaatatac tccggttacg gtggatgtcc tttcttcttt
     1741 cgaaggatgg aatgagtctt ttcaggcggc agcccgtaag aagcatatcc atttttcttt
     1801 tgatagtatg ccggatacgg attatcatac actggcagac atggagaagc tggaacgtat
     1861 ttatttcaat ctcctgtcca atgcctttaa gtttacaccg gaaaatggaa gaattgccgt
     1921 tcgtctgtct tccctttgta aagaggacaa gcgatggata cgtttcacgg tggcaaatac
     1981 cggttctatg atttctgccg aacatatccg caatgtattc gaccgtttct ataagatcga
     2041 tatgcaccat accggttcgg gaatcggact ggcattggta aaagccttcg tagaaatgca
     2101 tggtggtacg atctctgtag agagcgatga gaaacagggt acggtcttta ccgttgaact
     2161 gcctgtacag tcttgcgagg ctgttgctgc cgaaccggat accacccttg tttctgcgga
     2221 ttcccgtaca acagatgttc tattggcgga agaggaagaa ctggaaaaag gatatgactc
     2281 ttccaaatcg tccgtactga ttattgatga taatgaggat atccgttcgt atgtccatac
     2341 gctgttgcat acagactata cggtgattga agcggcagac ggctccgaag gaatccgtaa
     2401 ggctatgaag tatgttcctg acctgattat ttccgatgtg atgatgccgg gcattgatgg
     2461 cattgaatgt tgccgccggc tgaaaagtga gttacagacc tgtcatattc cggttattct
     2521 gctgacggcg tgttcactgg acgaacagcg tattcaggga tatgacggtg gtgccgattc
     2581 ttatatttca aagccgttca gttcacaact gttgctggca cgtgtccgca acctgatcga
     2641 ttctcaccgt cgtctgaaac agttctttgg tgacgggcag acattggcga aggaagatgt
     2701 ttgcgatatg gacaaggatt ttgtagaaag attcaagtca ttgattgaag agaaaatggg
     2761 agactccggt ttgaatgtgg aggacttggg caaggatatg ggactaagcc gtgtgcagct
     2821 ttaccgcaag attaaatcgt tgactaacta ctctccgaat gaattgctcc gtatcgcccg
     2881 tttgaagaag gcagcttctt tgcttgcttc ttcggacatg accgtagcgg agattggtta
     2941 tgaagtcggt ttcagttcac cttcttattt caccaagtgc tataaagagc agttcggaga
     3001 gagcccgaca gacttcctga aaaggaaagg atgatttcat tgagatcgta aagagggata
     3061 tatgaaagat tataaagtag ataaagagag tttttccgaa tcctttcgga aggaagtgta
     3121 cgaagtcgta tcccagatac ctgtgggaaa agtatctacc tatggaggta ttgctttgct
     3181 tttgggtgcc ccccaatgtt cgcggatggt ggggcgtgca ttgaaagaag tgccggatga
     3241 attatccatt ccttgccata gagttgtaaa ttccaccgga aggctggtac ccggttgggt
     3301 ggaacaaaaa caactcttgc tggcagaaga agtttctttc aaagctaacg gatgcgttaa
     3361 tctgaaagaa catttgtggc acgtggatga atgaaggatg caaggaaggt aagccatatc
     3421 atccgtatcc atacaataaa gaaaacccat acatgaagcc ataaggtcct ggtaatgaaa
     3481 tctctgatgg gaacagggac gaatatgtcg ataggaacga tgcataacag cacaaaacag
     3541 caccaaaata gaatcttgtc tgttgcggta cgtgttggcc tgctccaata ccagagcatg
     3601 aaacctgcca atgcgataat ataggtatgt ttctcggcgg agtcactcag taatactacc
     3661 cagcccatga gaatgcccaa agcttgggca cggaaggcaa aagacgacca tttgtggaaa
     3721 ttccccaaaa agagcagagt cagtagaccg agcattccta tctgaagtgc acggaagtgt
     3781 ggcaatgtcc atgctgcaat ggggcgggca tagaaaaatg aatcataagc tccggcggat
     3841 tgatgaacag caagactatg gcaccattct tcataatagg ggagcaaatc tgcaggagct
     3901 attttgatta acggtaacgt aagcaataca atgcccattg caacggcata gccaaagtta
     3961 cgccatacgt gaggatagca cagcaacaat gccagttcga aaattccata tactttggta
     4021 catcccgaaa tcatgattaa cagaacagcc agaaatccac ggtctttttc caataacgta
     4081 taggcgaata agaataaata ggctaccgtt atgttatact gaaatgaaag taaactttgt
     4141 cctaaaatca gtaacagaaa aaggaacata cggcatttct gttgctgggt gaattgttgg
     4201 ggcagcgtga agatcgccac aaagaacaat gaataattga atagattcca cgcgaaaggt
     4261 cccagccatg caggcagata cgcaaacgga gcgaacaata ccgtgaaaac aggagaataa
     4321 aggaagtagc gtccgtgagc ttctacaaat tcggttgtgt atgggctgat gccttgccag
     4381 aagaattgag tagcgtctga gaagaccata aagttttgat gccgtcctcg cataaattcg
     4441 agcagagtca ctataaaagc gagcaggaaa cctatcatgt agagattccg ccgactatag
     4501 aaaaacggca ttttggggtt ctttttacta aggaactgta cttggctttt gtcgtctagt
     4561 gtggcagtac ctgtttgttt ttcttttgtt gtgtaatgac aattatcctt ccccaggaaa
     4621 attgtaatag ccctgttgaa catataaatc tagtttagtt attgacgcca aatatacggt
     4681 gtttaggtga aatattcaaa cttattttat atttatctgc tggtttgttc tattttgctg
     4741 agtgataggg gaatattacc cggaaacttt ccatatcatt acaaataaag tcctctgtat
     4801 gccccggatt ttgaatataa tttgcatgtt taatctgttt tttgtatctt tgtgccagca
     4861 agatactgga acagactgtt tttatacata aaaatgctat ttttttgcta ttcgttgaaa
     4921 ggattatctt atcaaattct attccttttt taattactca gtctgtcaat aatcatttta
     4981 ttaattattt cgggattcat tgttatttgt cccgtattta aatcagaact ttatacgata
     5041 taaagaaaga ttcctgttat cgtttgttct tgtcttgctg tgtatattat tttaataacc
     5101 taaaccattt tattgtatga gtaaaataga aattaaagat ctctatctgg tttttggcaa
     5161 tgagaagcag aaggctttga agatgttgaa agaaggtaaa actaaaagtg aaatattgaa
     5221 agcgaccgga tgtacggttg cggtgaaaga tgcgaatctt tccattaatg aaggcgaaat
     5281 attcgtcatt atggggttgt ccggtagtgg aaagtccact ttactccgct gcatcaaccg
     5341 tttgatacgc cctacttccg gagaagtgat tatcaatgga acagacatag ccaaagtgtc
     5401 ggataaagaa ctgttgcaga ttcgccggaa agaactggct atggtctttc agaacttcgg
     5461 tctgcttcct caccgttctg tcttgcataa tatagctttc ggactcgaac tacagggagt
     5521 taaaaaggaa gaacgggaga agaaagcgat ggaaagtatg caactggtgg ggctgaaagg
     5581 ctacgagaat cagatggtaa gtgaactgtc gggtgggatg cagcagcgtg tcgggctggc
     5641 gcgggctttg gccaataatc ccgaagtcct gttgatggat gaggccttct cggcactcga
     5701 tcctttgatc cgtgtgcaga tgcaggatga actgctgact ttgcagtcga agatgaaaaa
     5761 aacgattgtc tttattactc acgacctgag tgaagcgatt aaattgggtg accggattgc
     5821 tatcatgaag gatggagaaa ttgtacaaat cggtacatcg gaagaaatcc tgaccgaacc
     5881 tgccaacgct tatgtagaac gatttgtgga gaatgtagat cgaagcaaga ttataacagc
     5941 ttcctctgtt atggtagata aacccatagt ggcacgtttg aagaaagaag gcccggaggt
     6001 gctgatccgt aagatgcgcg aacggaatct gaccgttctt ccggtagtcg attccaataa
     6061 tctgttagta ggagaggtgc ggttgaatga cttgctgaaa ctacgaaaag agcaaatccg
     6121 ctccatcgag tccgtagtaa ggcatgaagt tcattcagtg ctgggtgata cggtgctgga
     6181 agatattctt ccgttgatga caaaaacgaa ctcgccaatc tgggtcgtaa atgagaatcg
     6241 ggagtttgaa ggcgtagtgc cactttcctc attgatcatc gaagtaacgg gaaaagataa
     6301 agaagaaatt aatgaaatca ttcaaaacgc aatagaatta tgataaatat cggacaatat
     6361 atagaaactg ccattaattg gctcacagaa cattttgctt ccttttttga tgctctcagc
     6421 atggggatcg gaggattcat agacggtttt cagcacgtac tgtttggaat acctttttat
     6481 atcacaattg cagtgctggc tgcgctcgcc tggtttaagt cgggtaaggg gacagccgta
     6541 tttaccctct tgggcttatt gcttatttac ggcatgggct tttgggaaga aacgatgcag
     6601 acattggcgt tagtactttc ttccacttgt ctggcattgc ttttaggcgt tccgctggga
     6661 atctggactg ccaacagtga tcgttgtaac aagataatgc gccctgtcct cgactttatg
     6721 cagacaatgc ctgcctttgt ctatctgatt cctgccgttc tattcttcgg attgggaact
     6781 gtgccgggag cttttgccac catcatcttt gcaatgcctc ctgtggttcg tctgaccggc
     6841 ctgggcattc gtcaggttcc taaaaacgta gtagaagcct cccgctcttt tggagctact
     6901 ccctggcagc ttctttataa ggtacaattg cctttggcgt tgcctactat tctgacggga
     6961 atcaaccaga cgatcatgat gtcactttcg atggtagtga ttgccgccat gatttctgcc
     7021 ggaggattgg gagaaatcgt gctgaaaggt atcacccaaa tgaaaatcgg actcggattt
     7081 gaaggcggta tcgcagtcgt gatattggcg atcgtgctgg accgcatcac tcagggcatg
     7141 gcagataaca gaaaaagtaa aaagaaataa gaatcacacc aaagaaagga ataatcaatg
     7201 aataagataa aaatgattgc ggcaatgttt attgccggca tactcttaac cttcgtttcc
     7261 tgcggagaca acggaaagag taagaagata agtatcgctt atgccaactg gtcggaaggg
     7321 attgccatga caaaccttgc caaagcgatt tttgaagatc agggatacga tgtaaagttg
     7381 ctgaatgccg accttgcacc tatatttacc tctatctccc gtaagaaagc agacgtattt
     7441 atggatgtct ggatgcctgt cactatggaa gattatatga aacaatacgg ggataaactc
     7501 gaagttatcg gggatattta tgatggtgcc cgtatcgggc tggtggttcc ggattacgtt
     7561 acgatcaact cgatcgaaga actgaacgcg gaaaaggaac gtttctccgg tcagattgtc
     7621 ggtattgatg ccggagccgg tattatgaaa gctaccgatc aggccatcaa agactatgga
     7681 ttggattata aactgatgac ttcgagcgga cctgccatga ctgcttccct aaagaaagcg
     7741 attgataaga aagactggat tgtcgtgacg ggatggacgc ctcactggat gttcgaccgt
     7801 ttcaaactga aagttcttca ggacccgaag ctgatatatg gaaatgcgga aaccattcat
     7861 accatagcgt ggaaaggttt tagcgagaaa gatccttttg ctgccgaact tctgggcaat
     7921 attcgtctga ctgatgcgga aatcagctct ttaatgactg ctctggaaga ggcgcagacg
     7981 acggaaagac aggctgcccg tcaatggatg gaagaacatc aggaactggt aaacagttgg
     8041 attcctaaga aagattgata agcaaacact acttcaacca tcccgccatt ctttctttac
     8101 catagaagta gtagaaaagt agtcccagcc agctggtaag aacgattaat acaatcgcta
     8161 taagcctttt ctctacagcc gcatttatat tccaaatctc tatggcagct ctgaaagtca
     8221 gtatcaaacc gacaatccaa ataacaaatc cgatcatatc tttagagttt taatgaatat
     8281 cttcgtgaga agtaatcgtt acttctaata tataaacaaa aaaggcagga atctgtttcc
     8341 aggattcctg ccttttatta tgtacaaagt atttctactt attattcagc tgtatcagct
     8401 ccccagtttt ctctggcaag acgtttgtag ctgttgtaac gccatttagc gttttcttca
     8461 gcagctttaa acagttcttc agcttcagca gggtattgtt tcattacaga agcgtaacga
     8521 acttcaccct tcaagaaacc ttggaagtct tcccagttag gttctttgct atccagctgg
     8581 aacggattct tgccttcttc ttccaaagca gggttgtaac gccacaagtg ccagtaaccg
     8641 cacttaacag ccttttcttc ttcttcctgg ctcttaccca taccggcttt cagaccgtgg
     8701 ttgatacatg gagcgtaagc gatgatcagt gatggtcccg gatatgcttc agcttcgcgg
     8761 atggctttca gagtctgagc ctggtcagca cccatagcaa tctgagcaac atatacataa
     8821 ccgtaagtag tagccatcag accgaggtct ttcttacgta cacgcttacc tgcagcagca
     8881 aacttagcga tagcgcctac cggagtagct ttagaagact gaccgccggt gttggagtaa
     8941 acttcagtat ccagaacgag gatgttaacg tccttaccgg aagcgattac atggtcaaga
     9001 ccaccgtaac cgatatcgta agaagcaccg tcaccaccaa tgatccactg gctgcgtttt
     9061 acaagatatt gttgcagttc agcgatttgt ttgcagtggt tacatttatc cttgttagct
     9121 tcaacaaccg gaatgatctt agcagccaat tccttagtct tgtccgcatc cagcatattg
     9181 ttgatccatt cagcgaacag ttcttttact tcagcaggag tgcaatcagc agcaatagcc
     9241 tcgttcatca ctttcacgag acgagcacgc atcttttcgt tagccagttc catacccaaa
     9301 ccgaattcac agaagtcttc gaacagtgag ttagcccaag caggaccgtg tccgttttcg
     9361 tttgtagtat acggagtaga aggaacagaa ccagagtaga tagaagaaca tccggtagcg
     9421 ttagcaacca tttcacggtc accgaacaat tgagaaatca atttcacgta cggagtttca
     9481 ccacaaccag agcaagcgcc ggagaactca aacaacggag tagcgaactg tgagttcttc
     9541 acgttagcct tgatatcaac aagatgttgt ttagtcttca cgttttcagc acagtaagtc
     9601 cagttttcag cttgagccaa ttggctttcg aggtgtttca ttgtcaatgc tttgccaccc
     9661 ttcttcggat tacccggaca gatgtcagca cagttaccgc aacccagaca gtcgagaacg
     9721 tccacctgga tacggaatgt cataccgtcg aatgctttac ctacagcttt cagttgttcg
     9781 aacttagcac ccttctgctc ttcagcatcg agtacgaacg gacggataga agcgtgagga
     9841 caaacgtatg cacacttgtt acactggata cagttttcag cattccattc gggaacgaat
     9901 gcagctacac cacgtttttc gtatttggaa gtaccttgat accaagtacc gtcttcgata
     9961 cccttgaatg cagataccgg cagcaagtca ccgtcctgtg cattgatcgg acgaactact
    10021 tcgttgatga aagcaggatc attgttttct gcttttgcat catccggcag gttagcccaa
    10081 gcaggatcga cagtcagagt cttgtattca ccaccgcggt ctacagcagc gtagttcttg
    10141 ttaacaacgt cttcaccctt cttgccgtaa gacttaacga tgaatttctt catctgttca
    10201 acagcttgat ctacaggaat aacgcctgtg atacggaaga atgcagactg aaggattgta
    10261 ttggtacggt tgcccagacc aatttccatt gcaatctgag ttgcgttgat atagtataca
    10321 gagatgttgt tctgtgcaaa gtatttcttc accttgttag gcaggttctt agccagttct
    10381 tcgccttccc agatggtgtt cagcaagaaa gaaccgttct tacgcaaacc acgtgttaca
    10441 tcgtacatgt gcaggtaagc ctgaacgtga caagcaacga agttcggagt gtttaccaaa
    10501 taagtagaac ggatcggatt atcaccgaaa cgcaagtgag aacaagtgaa accacctgac
    10561 ttcttagagt cgtaagagaa gtaagcctgg cagtgtttgt cagtgttgtc accgataatc
    10621 tttacagagt tcttgttagc acctactgta ccgtcagcac ccaaaccgta gaatttagct
    10681 tcgaacatac cttcgccgcc taaagcgatt tcttcttttt gaggaagaga agtgaaagta
    10741 acgtcgtcta cgataccgat agtgaagtgg ttcttcggca ttggcatagc caagttttcg
    10801 aatactgaaa ggatttgagc aggagtagta tcttttgaac ccaaaccgta gcgaccgcca
    10861 acgataaccg gagcattttc tgcaccgtag aagcagtctt taacgtcaag gtaaagaggt
    10921 tcgccgttag cacccggttc tttagtacgg tcaagaactg cgatagtctt agcagtctta
    10981 ggtacagcag ccaggaagtg tttagcagag aacggacgat acaagtgtac ggcaaccata
    11041 cctacttttt cgccgtttgc taccaagtgg tcgatagctt cgcgggcagc ttcagttaca
    11101 gaacccattg cgataattac gcgttctgca tcttctgcac cgtagtaatc gaacaaaccg
    11161 tatttgcggc ctgtgatctt ggaaatttcg ttcatgtatt cttctacgat agcaggaact
    11221 gcttcatagt agttattgca tgattcacga tgttggaaga agtggtcggg gttttcagcc
    11281 ataccacggg caaccggctt catcggattc agtgcacggg cacggaattc agccaaagct
    11341 tcctggtcga tcagcggagc caagtcctca ttttccaaca tttcgatctt ctggatttcg
    11401 tgagaagtac ggaaaccatc gaagaagttc atgaacggaa cgcgtgattt gatagtagcc
    11461 aagtgggcaa caccggccaa atccataact tcctgtacgg aaccttcagc caacatagcg
    11521 aagccagtct gacgagctga cattacgtct tggtggtcac cgaagataca caatgcgtga
    11581 gaagccaatg tacgagcaga tacatggaat acgcaaggca agaactcacc ggcaattttg
    11641 tacatgttag ggatcatcag gagaagaccc tgggaagcag tgtaagtagt agtcaacgca
    11701 ccagcctgaa gagaaccgtg aactgcaccg gcagcaccac cttcagattg catttcctgt
    11761 accaatactg tttcgccgaa gatgttctta cgtcctgcgg cagcccattc gtctacgtac
    11821 tcagccatag tcgaagaagg agtgatgggg tagatagctg ctacttcaga gaacatatac
    11881 gagatatgcg ctgcagcctg gttaccatca caagtgatga atttcttctg tttagtcata
    11941 actaaattaa atatttaagt aaataaatct tttaatataa aaagccgaac atccagagag
    12001 gtatctggtt gccccgacct atttcagcct tatgcaacgc gtacgttaca ttcggattgt
    12061 tcttgatctt tgcgccttcc tggcaaattt tgaacggcat tacttcgtcc accataaaag
    12121 agacgttttt atctccttta tgtaccttat ggtctttcca taaagaattt gcaaagaatg
    12181 tgtcgagcac atcctgctct tccactttca ccggatagat ggaatacatc aggttggagt
    12241 tgtgcatcat tatctttgaa ggttttttag ggaattcttc ccctttcgga taaaccagat
    12301 taatgagtcg cgcatctgcc agatacttga tatagttcat caccgtggcg cgagatgtct
    12361 gtatgtcgct tgccagttgg ctcacatttg gagccttcgg tccgtcgaca gcgagcaaat
    12421 atagtaattt ttttatcttt gaaagatatt tcagttcaat ttgtttgatg agaagtatat
    12481 ctacttccac catcatgttc atcgttttca gcaaattctc cgaaaagtta cgcttttcga
    12541 ggaagaacgg atagaatccg tggtgcagat aatcctgaaa atagtcaagc ggacgaactt
    12601 tggagagtac tcctttggca atctgttcgt gagtgctaag aatttcttcg agactgtatg
    12661 ccctgaattt catgcctgtt tgcaagttca ggtattcacg gaaagagaat ccgcgcaggt
    12721 tatagctctt cgcgatatca cgcagttcaa gattttcctc tttcagtcgc atcacggatg
    12781 agccggtaaa gacaatcttc agattaggaa aacggtcgta acacatgcgc aactctctgc
    12841 tccattccgg atgtttgaac acttggtcaa tcaacaatac ttttccgcca cgtttctgga
    12901 attcgtaggc aaagtctaca atgctgtgtc ccgagaaata gaaattgttc atgttgatga
    12961 acagacagga acggtcgttc ccgaatttct ctttggcgta ttggagaagg aaagtggttt
    13021 ttcctacgcc acgtgtccct ttgataccaa tcaggcggtc gctccaatcg atctcgtcca
    13081 taagatcgcg gcgaacgggg gcattggtgt gctcaacgag gtaggcgtgt gtgcgataga
    13141 atgattccat ttcgtttctt tgtttttcgg ctggcaaata tagtgctttt tttaggattt
    13201 gcaaagtaga gatagcaaaa atgtgcttta atttataagt ttctctttat tgtgtaagtt
    13261 cctgattatt tcctgtatat atttgcagaa taatgtgttg aatccatctt tgacatgacg
    13321 aaaagacctg tttatatatt caatccggag catgatatgg cgttggcaag cggtgagacg
    13381 aactatatgg cgccggcttc cgcccgacag atggcgagtg acctggcgtt gcttcctatg
    13441 tggtatgccg aagcgggaag tgcggtgctt gcaccgtctg cttataatgc ggacttcctg
    13501 aaaacaaaga gtgaactttt gggcatggat gtggccttgt tgacggaacc ggaagtggct
    13561 gacggtaaag accggaagtt ctctccgtgg gggtgggacc ctgctttgcg gaagcgtttg
    13621 atgacattgg gggcagatca gacggagctg ccttctgcgg attatatgaa tattctgaga
    13681 gagcattcgc atcgtctgca ggcggtaaag ttgttgcctg ggttgcggtt gaatgaatac
    13741 ttctgtggag aatcttttta tttgagtact ttggcggagt gcagtgcgtt cgtcgaaggg
    13801 cgggaagcgt gcttgttaaa agctccgctt tccggaagcg ggaaaggatt gaattggtgt
    13861 aaaggcatat ttactacttt tatttccggt tggtgtgccc gtgtcgctgc ttctcagggt
    13921 ggggtggtag gcgaacctat atataataag gtggaagatt tcgctatgga gttttatgct
    13981 gacgggagag gaagggttgt ttttgccgga tattcggtct tccacacggg tgggagtggg
    14041 atgtatgcag ggaatgactt gctgtctgac gagaagattc tgcagaaact atcggcttat
    14101 gtgccacaag aagaatttat caggctgcgg actcgtttgg aagaagaatt gtcagctttg
    14161 ttcggtggct tttatcatgg atacttggga gtggatatga tgatttgtca ttttccggat
    14221 gaagcgcctg tttaccggat tcatccttgt gtcgaaatta atctgcgaat gaatatgggg
    14281 gtggtggcat ggctcttgac ggatcgttat ttggctgcgg atgcggaagg agcttttcgg
    14341 attgattatt atcctttagc cggtcaggct ttggaggaac atcggcagat gtcggcttcg
    14401 ttccctttgt ccgtagagaa taatcgggtg tgtgccggat atttgccgtt agtaccggtg
    14461 acgcctcaaa gccggtatcg tgcgtttctt ttgcttactc tcccccagtg aaaaagatag
    14521 tgcttttgct ctcatgctct aacagttcgt ctgtatccct ttattcatcg atgttttagc
    14581 tgttagagat ccagtggtag cagagtgaga gcaaggactt gctctcactc tgcatcgtcc
    14641 tgataaatac cgtttttact gtgttattct ttgatttaca ggatgttaat atctgatatc
    14701 tcaactgtta acgtttgatt tctcagatat taataattga gaaatcaagt attaaggact
    14761 gataatttat gtattattga ctgatatatg atttaatgtt ttcagagaga gcagtactat
    14821 tgaagtagct gatgcgttca atgtgattgg aacatgcggt taagtcaatc aaatcaacag
    14881 tagttgtctt accctggatt tggttgacta ctataagtat caactaaaat gaataaaa
//
