LOCUS       gnlProkkaMJCLAJGF_65   11579 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MJCLAJGF_65.
ACCESSION   gnlProkkaMJCLAJGF_65
VERSION     gnlProkkaMJCLAJGF_65
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:31:46
            Original ID  :: gnl|Prokka|MJCLAJGF_65
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11579
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11579
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3005:6579]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3006..6579
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11579
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11579
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..254
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="MWNLFYQLGKGFFIPIIIAILIALPVAWGSMNAWLAHYPFRTELK
                     VWFFLLPVVLMLLISFLTVAGQTIKVVYSKPARSLKYE"
     CDS             1258..2073
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="MELATEALSYNNQNIASEAPKLLLCSSIASVSDQGSNKGVTPLAG
                     IGKEHPELNWYYLYLPNKELKRYIGVFSGRKSVKLRKPSGEAEERYFCFKVFSYTSADH
                     RKRFEQCAYTKEEYTARRDSARVVKEAFATGSARKLNALTDEKEIEGNGWLFVCAPLDQ
                     LELILSAMFPRQYLVTDYNTHCAAVIPQRQMEEFIYLYESMPYNIELMNRPLEDYLQKK
                     QRIRITGGVFRGKEGCIMRLHRNTRLVFAFGNMTVAVSYLHAFPFEKVE"
     CDS             3006..4328
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 207.8;
                     E-value: 3.3e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_3"
                     /sec_met_domain="CTP_transf_like (E-value: 3.9e-16,
                     bitscore: 49.1, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.6e-120, bitscore:
                     390.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.4e-64, bitscore:
                     206.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENSKKVYVGMSADMIHPGHLNIIREAAKLGCVTVGVLTDAAIAS
                     YKRLPYLDYNQRSEIVRSLKGVDNVVPQETLDYVPNLERLKPDFVVHGDDWMQGVQSNV
                     RNRVIECLKQWGGKVVDIAYTKGFSSSAENERLKEIGTTPEIRQKRLRRLINAKKIVRI
                     LESHNGLTGLIAENVSVIVNGVKHEFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLND
                     TLECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAVIIEDKVGLKQNSLFGTDAVQIQ
                     DTIEGFCNKIRTGKNAQVSDDFMIIARIESLIAGKSIDDALARAAAYVEAGADGIMIHS
                     KNKSGDDIKEFCQRFRVANVSTPIVVVPTTYSHITETELASWGVNVVIYANHMLRSAYP
                     SMVNCAKSILMHERSQEAVNDYCMPIKEILELIPGTKKTLK"
     CDS             4325..5464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 53.7;
                     E-value: 2.5e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 4.6e-20, bitscore:
                     61.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-18, bitscore:
                     55.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPDFFINSLSQRGIDFFAGVPDSLLKNICAYIADHKDGHHNII
                     AANEGAAVGLAAGHYLATGHIPVVYMQNSGEGNIINPLASLTDKDVYSIPLLLLIGWRG
                     MPGVHDEPQHVKQGKVTIPLLDVMGIKHVVMSKDEKELLKQIEDALFFMETKNEAFAFV
                     IEKDTFDSYELQSGSTSTLSMSREETIQAIASSIGQEDCIVSTTGMISRELFEHRTQMK
                     QGHEKDFLTVGSMGHASQIALGIALEKTDRRIWCFDGDGAVIMHMGSMAIIGSKQPKNY
                     IHVVFNNGAHDSVGGQPTVGLDIDLPGIARSVRYNAVHTVSDMNGLKKVLSDIRLEDGP
                     VLLEVKVRKGNRKDLGRPTTTPIQNKEAFMGFLQDKELN"
     CDS             5467..6579
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="Fe-ADH (E-value: 3.1e-72, bitscore: 232.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEYYIGPDLNTQLAALLQKLNVTKVFLVRGKKSYTSCGASDVMD
                     AVLSGRGIKTVCFFDFLTNPRVEDVRKGVLLCKSQCPNIILAVGGGSALDMAKLIRYHI
                     YKETDSYIPLVVIPTTAGTGAETTHFSVCYINGEKQSIADSAMLPDYAFVCSELTSHND
                     AYLTACTGFDAVAQAIESYWSVNSTDESRSYSLKALGLLWKQLPLLIKNLNNKELRSEV
                     AEGAYYAGRAIDITTTTAPHAFSYKFTSLYGIPHGHAVALTFPYFFALNLCGERLQSTL
                     NSYEYGQRMKLLVQFLDADRSDFLSCQLHMSTYISSLGLSAKALTFDELASAVSSFNEQ
                     RGRNNPVVIDEEVKSGLQNYFMELKESDKE"
     CDS             6616..7335
                     /locus_tag="ctg65_6"
                     /transl_table=11
                     /translation="MRIQNLYYKLGGKKGGFLQTKWSGYIQKKTVKRNRKLLQDKGICA
                     LDAMSAACKEAGVSFGMEFGTLLGAYRNQGFIPYDDDMDLTMWAEDCSRDFENVLLKYG
                     FYKKRAFYLVTVDSNGKRTRKLTEIALDYDGLQVDIFFSFRKTEITRSIFVYCPPVVNE
                     KMTAREFVLPIGLSPRLVTVRNKQYPAFADPHKTLSLIYGEDFMIPRKNASATKSIQSN
                     VIIHDMFVAYGEGFMLE"
     CDS             7363..8784
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_7"
                     /sec_met_domain="Polysacc_synt (E-value: 8e-38, bitscore:
                     120.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTSGFVAVIWSLIERLSSQVISFLLGIVLARLLSPSDYGIVGM
                     TMIFILLSNVFIEAGFANALIRKTNRTEQDLSTAFYFNVLIGILAYCILWIGSPFIADW
                     FKEPLLSLLIRISGVNVLLNSLCIVQTALLTANLDIRRQTIINLCGQIPAGLITAILAY
                     NGLGVYALVFQTIIASCIRVIMLWLYTPWRPQEKFNRESFLSLWNFGSKLLGANLIGTA
                     FNQVSSVLIGKYIGKSDLGYYSKASNLCGNIDSVSSGVVQKVALPMLSEFQKDKVLLSE
                     KFREMMRLLIMGMAPLISFFCFTASDIIVILWTEKWIQCAFVFQILIVGAAFNPIGHMS
                     LSLMQTVGNSALILKLEVPKKIIYCIYLAIGFCYGLVGLAVAQVLINITGALINMWATK
                     RIVKYSYMRQIVDVLGYMVIAFIVGYIWFNMIHTGYMFFNILLMFMLIVFTYFAILVMI
                     KDAILIKYVRKIIGL"
     CDS             8988..10268
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_8"
                     /sec_met_domain="Wzy_C (E-value: 1.5e-09, bitscore: 27.6,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIICVFIFLIISLLLIVNFKCTFMVVSACSMVLGCMNGVGPFGM
                     YQAVSIAAFSIFMLRYFYWKDMRTYPLLFSSILLIVSYVLSNHYAVYRHYGSLVSCIVV
                     DVASLFVFYQIISKNSRYIFIYIRTCVILSLVVGVYTLVETIISSNHYMFIVNSLELYS
                     QDIIVEDIRFGMKRAQAIFGMHTTLGGFSTMMAGLLLWVRLNCTLYVKKLGKKKLSIAI
                     GLMIIAVFLTGTRSTIAGLAVVLMSFFSFKHIKMKYVFIAIVSVVIGFMALDAYLDKII
                     LSFTDTESVGGSNTDMRSIQFELAALFMMQSPFLGNGISYTFEYVADKYKEMCGAESLW
                     IPIMIDFGILGITAIIVFIIQVGYYIKKYCEIRLLFFLLGILVFNSLSSIPAFSFTQLF
                     YLFVIIAFLKKYQESICNSPSSFPSIK"
     CDS             10232..11215
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_9"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-35, bitscore:
                     111.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLSIIIPVYKVEKYIRDTLQSIYRQQYDENLFEVIVINDGTPDD
                     SMRIVAEFTNKHANLHIINQKNQGLSCARNAGLKIAQGEYVWFVDSDDTVTEESIGKVI
                     ECIERSKADVIGFSILKVSEANRVSEVESAIWNEHCRFSSNQIVCDKSILFSLHTGAAV
                     RYVYRRAFLQMNHLRFYPGILYEDQEFLPRVFSLANSFYISSFISYRYLLRSSGSIMSQ
                     FSLRSLRDTLTIVRSYETWLQEEIKGKSALINAYINGCVFNHTYWLLSFKAVTFRDEQK
                     EFMRDHYAEIRRKCLTAGWKSLKGNFRLTRAVRLLMVFLIPHHLIK"
ORIGIN
        1 ctcgttggaa tttgttttat cagttgggta aaggtttctt tattcctatt attatcgcta
       61 ttctgattgc gttgcctgtg gcatggggca gcatgaatgc atggttggct cattatccgt
      121 tccgaacaga attgaaagtg tggttctttc tgcttcctgt ggtcttgatg ttgttgattt
      181 cttttctgac tgtagcagga caaaccataa aggttgttta tagtaaaccc gctcggtcat
      241 tgaaatatga ataatggaat ataagatatc cgtggttagt aattcattta caaggaatat
      301 catttaaaac caatataaat tatcgtacca gttcattatg gcagatcaat actgataaac
      361 tttgaaaacc ttttgaattt ttctacaaaa ctaattttgc gtctaaaatt attttattaa
      421 ttttacagcg tttttaagga gagtctaact ctctatagtt acaaatgagc gatgagaaag
      481 ggtgccctga tggcatcctt tctcttttgt agtgtgtttt tgtataatct atattgtatt
      541 ttacttatgt cacgattatg tgaaatcacg atacatcttt tgtatttccg tttcttttac
      601 ttttatcaga cttaatcgtt tttcttgcat taaaaaacaa ttggacctcc ctttgttata
      661 tatttaacac tcttttaatc tcattttgtt gaacaatcta cgcgattcaa atgttaatat
      721 aatgtgtttt tcatagtaat agatttaaga ttaatagtta gtatttgctt gtgaaagtca
      781 gtacacttac ggataaaagc gtttatccga aaagaaaaga gaggcgaccg gaaacggaag
      841 cctctttctt tttgagcatt tttagttcac cataattatt gtgagaggaa aattgattct
      901 gattgtataa ataatataat gtgttgaaaa taagattttt ccctttttaa gcctttaata
      961 aaaaatggag ttctcttagt aagagaaccc cattttgctg caaagatagc tataattcct
     1021 taatacagaa aattccgcat taaaaaagta ttccaaagta tgcttataaa tgacaattgt
     1081 ttgcaaaaat aatatgaaag gttataacta taggacactc tatcaggcat ttaagtaaac
     1141 ttggggttct cttactaaga gaaccccaac aaaaaaacga aaattgatgg cttattcgag
     1201 cctcattttt tagaagaata atttaattat gatgttttga tggaaataaa aagtcctatg
     1261 gagcttgcaa ccgaagcact ctcttataat aatcaaaaca tagcgagcga agcgcctaag
     1321 ttactgctct gcagttcaat cgcttccgtc tcagaccagg ggtcaaataa gggagtcacg
     1381 ccattggcgg gaatagggaa ggaacatcct gaactcaatt ggtattatct gtatctgcct
     1441 aacaaagaat tgaagcgcta tatcggcgtt tttagtggca ggaagtccgt aaaacttcgt
     1501 aagccgtcag gtgaagcaga agaaagatac ttttgtttca aggtattttc ctatacttcg
     1561 gcggaccaca ggaaacgctt cgagcaatgc gcctatacta aggaggaata tactgcccgt
     1621 cgtgattccg cccgggtagt gaaagaagcc tttgccaccg gttccgcccg gaaattgaat
     1681 gctttgacgg acgagaaaga aatcgaaggc aacggctggc tgtttgtctg cgctcctttg
     1741 gatcagttgg aacttatttt gtctgctatg tttcctcgcc agtatttggt gacggactat
     1801 aacacgcact gtgcggcggt catccctcaa cgtcagatgg aggaatttat ctatttgtac
     1861 gaatccatgc cttacaatat cgagttgatg aaccgtcctt tggaggatta tcttcagaag
     1921 aaacaacgca tccggattac cggtggcgtt ttccgaggga aggaggggtg cattatgcgg
     1981 ctgcatcgaa atacaaggtt agtgttcgct tttggaaata tgacggtggc tgtgagttat
     2041 cttcacgctt ttccgtttga gaaggttgag tgaagatagt ttctgttctt gtgctcatct
     2101 tttattgaaa taagcattat tgagcaaaat aatatttgaa tttgcttgga tatatgatga
     2161 aaaatcatgt tccttgcaaa attaactcat acttatggca aaacagataa ctcctactcc
     2221 tcccttgaaa gggcaggctg caattgattt cattacggaa atcagcaaaa aaagaaggtc
     2281 acccagcaga aaaggctaag gtgaaagagg gggcatgcgc ataaaggcgt tgctgacctt
     2341 taatttctag cactcgtatg aataaagata ttcgggtaat ttgcttgtca gaagattatg
     2401 aatttaaacc gtttgactgt ggaaatgatg atctgaatgg tttcttgtta caagattatt
     2461 ggatgatgag gaacagccga tagataacct aggggagtga gccattcgaa aatttactac
     2521 tcaacgaaac aattcacttt attacggtag tgatgccggt gctgaaatgg ctgccacata
     2581 tcatggtgtg attggaacgg tgaagctttt gggtagctct atctggaatt tcatcggaat
     2641 ttttttcaaa aatatcttta acggatgcag ggagtatgtt aatatggttc ctgacaaaat
     2701 cactttggct acaagttaat gttaaattca aagctgatta attaacagaa ctcagtttag
     2761 ggcacagtta tgtgcccttt taaaggggga tgctctaaat tgagtgctta gagatggtaa
     2821 gagtctctgt tgaatatcat catctcaact tgcaaaatgt atttgtacta agaaactaaa
     2881 atatatttag cattactttc ctttaataac agtcgtatga ctaaagttcg ttgcatatta
     2941 aacgatgata tctacataca tgatgctgga tatgtaaaaa tgtaaattca aattcaatca
     3001 attatatgga aaatagtaag aaagtttatg tggggatgag tgcggatatg atacatcctg
     3061 gtcatcttaa tataatccgc gaagcggcaa aacttgggtg tgtaacagtt ggcgtgctga
     3121 cagatgctgc tatagcaagt tacaagcgtt taccttatct tgactataat caacgatcag
     3181 aaatagttcg ttccttgaaa ggagtggata atgttgtccc tcaagaaaca ttggattatg
     3241 ttcctaatct tgagcggttg aagcctgatt ttgttgttca tggagatgac tggatgcagg
     3301 gagtccagtc caatgttcgt aatcgggtta tagaatgtct gaaacaatgg ggaggaaaag
     3361 ttgtcgatat agcttatacc aaaggctttt cttcttccgc agaaaatgaa cgtctgaaag
     3421 agataggaac tactcctgaa atccgtcaga aacgtcttcg tcgtttaatt aatgccaaga
     3481 agatagttcg catattggaa tcccataatg gcttgaccgg tttgatagca gaaaatgtat
     3541 ctgtaatcgt taatggcgtt aagcatgaat ttgacggtat gtggtcaagt tcattgacag
     3601 actctactag taaagggaag cctgacattg aagctgtaga tttgaccaca cgtttgcatg
     3661 acttgaacga cacgttggaa tgtacaacga aacctgtcat attcgatgga gatacgggcg
     3721 gtaaaattga acattttgta ttcacagttc gtaccttgga gcgcttagga atttctgctg
     3781 tcatcataga agataaggta ggtttaaagc agaattcttt gttcggtaca gatgcggttc
     3841 agatccaaga tactattgaa ggattttgta ataagatccg tacaggaaaa aatgcacaag
     3901 tgtcggacga ttttatgata atagcccgta ttgaaagcct gattgccgga aaaagtatag
     3961 acgatgcact ggcgcgtgcg gcggcgtatg tggaagcagg tgcagatggc attatgattc
     4021 atagcaagaa taaaagtggg gatgatatta aggaattttg tcaaagattc cgggttgcta
     4081 acgtatctac tcccattgtt gtagtaccta ctacttacag tcacataaca gaaaccgaat
     4141 tggcttcatg gggtgtgaac gtagtaattt atgcaaatca catgttgcga agtgcatacc
     4201 cctctatggt taactgcgcc aaatcaatcc ttatgcacga acgctcacag gaagctgtta
     4261 atgattactg tatgcctatc aaggagattt tggaacttat acccggaaca aaaaaaacac
     4321 taaaatgatt tcacctgatt tttttattaa tagcctttcc cagagaggca ttgatttctt
     4381 tgccggagtt cccgattcat tgctgaagaa tatctgtgcc tatattgcag atcacaaaga
     4441 cggacatcat aatatcattg cagctaatga gggtgcagct gtaggtttgg ctgccggaca
     4501 ttatttagct accggtcata tacctgttgt ctatatgcag aattccggtg aaggaaatat
     4561 catcaatcca ctggcgtcgc ttacggataa agatgtttat agcattccac tcttgctgct
     4621 tatcggatgg cgaggaatgc caggtgtgca tgatgaacca cagcatgtca aacaggggaa
     4681 agtgactatc ccgttacttg atgtaatggg cattaagcac gttgtgatga gcaaagatga
     4741 aaaagaattg ttaaaacaaa tagaagatgc cctctttttt atggaaacaa aaaatgaagc
     4801 ttttgctttt gtgatagaaa aagatacatt cgattcgtat gaattgcaat caggcagtac
     4861 ttcaacattg tcaatgagtc gtgaggaaac cattcaggca attgcttcat ctatcggtca
     4921 agaagactgc attgtgtcta ctactggtat gatttctcgt gagttgtttg agcatcgtac
     4981 ccaaatgaaa caaggtcacg agaaagattt tctcactgta ggttccatgg gacatgcttc
     5041 tcaaatagct ctaggtatag cattggaaaa gacagaccgt aggatttggt gctttgatgg
     5101 cgacggagct gtaattatgc acatgggttc tatggccatt atagggagca aacagccgaa
     5161 aaattatatt catgtagtct ttaacaatgg tgctcatgat tccgtaggtg gccaacctac
     5221 ggtgggcttg gatattgatt tgccggggat agcccgttcc gtaagataca atgcggttca
     5281 tacggtttct gatatgaacg gtttgaaaaa agttctgtcg gacattcggt tggaggatgg
     5341 tcctgttttg ctggaagtga aagtaaggaa aggcaatcgt aaggatttgg gccgtcctac
     5401 taccacgcct atacaaaata aagaagcttt tatggggttc ttgcaagata aagagttgaa
     5461 ttaattatgc aagaatatta tatcggacca gacttgaaca ctcaattggc tgctcttctg
     5521 cagaaactaa atgtaacaaa ggtgttcttg gtaagaggca agaagtccta tacatcctgt
     5581 ggtgcatcgg atgtgatgga tgccgtatta agcggaaggg gtataaaaac tgtctgtttt
     5641 tttgacttct tgacaaaccc tagagttgaa gatgtcagga aaggggttct tctatgcaag
     5701 tcacaatgtc ccaatatcat attggcggta ggcggtggca gtgcacttga tatggctaaa
     5761 ctgattcgtt accatatata taaagaaaca gatagctata ttccgctagt ggttatccct
     5821 acaacagctg gaacaggtgc ggaaacaacc cattttagcg tgtgttatat aaatggggag
     5881 aagcagtcga tagctgattc tgcaatgctt cccgattatg cttttgtctg ttcggagttg
     5941 actagccata atgatgctta tctgacagct tgtacaggat ttgatgctgt tgcgcaagct
     6001 atagaatcct attggagtgt gaattcaacg gatgaaagcc gtagttattc gttgaaagca
     6061 ttaggtctgt tatggaagca attgcctttg ctgataaaaa acttgaataa taaggagcta
     6121 agaagtgaag tcgcagaagg ggcgtactat gcaggtcgtg ctattgatat aacgactact
     6181 actgcgcctc atgctttttc ttacaaattc acaagtctgt atggaatacc gcacggtcat
     6241 gcggtggcac taacttttcc atactttttt gcattgaatc tttgtggtga aagactacaa
     6301 tctacattga atagttatga atatggacaa agaatgaagt tgttggtaca atttctggat
     6361 gctgatagaa gtgacttctt gtcttgtcag ctgcacatga gtacttatat ttcttcattg
     6421 ggtttgtctg cgaaagcatt aacattcgat gaattagctt ctgctgttag ctcttttaat
     6481 gaacaaaggg ggcggaataa tcctgttgtc attgatgagg aggtaaaaag cggattacag
     6541 aattatttta tggaattaaa agagtcggac aaagaatagg ttgatcctaa ccatttccaa
     6601 tttaaattat taattatgcg tattcaaaat ttgtattata agctaggggg gaaaaaagga
     6661 ggtttccttc aaaccaagtg gagtggatat atacaaaaaa aaacggttaa gagaaataga
     6721 aagctattgc aggataaagg aatatgtgct cttgatgcta tgtcggcagc ctgtaaagaa
     6781 gctggtgtca gctttggaat ggaatttgga accctgcttg gagcctatcg taatcaaggg
     6841 tttattcctt atgatgatga tatggacctt accatgtggg cagaagactg ttctagggat
     6901 tttgaaaatg tactacttaa atatggtttc tataaaaaaa gagctttcta tcttgtaacc
     6961 gtagattcta atggaaagag aacaaggaag ctgacggaaa tagcattgga ttacgatgga
     7021 ttacaagttg acatattctt cagtttcaga aaaacggaaa taacacgctc gatttttgtt
     7081 tattgccctc ctgttgtaaa tgaaaaaatg acggctcgtg aatttgtact gcctataggg
     7141 ctttctcctc gattagtgac tgtaaggaat aaacaatatc cggcttttgc agaccctcac
     7201 aagactcttt ctttaattta tggagaggat tttatgattc cacgtaagaa tgccagtgcg
     7261 acaaaaagta ttcaatcaaa tgtaataatt catgatatgt ttgtagctta tggagaaggt
     7321 tttatgttag agtagtgtgg ttgtagactt ttatttcttt ccatgaagag aacatcgggt
     7381 tttgttgctg ttatttggag tttgattgaa cggttgtcaa gtcaggtaat aagtttcctt
     7441 ttgggtattg tattagcgag attgttgtcc cctagcgatt atggtatcgt tggaatgaca
     7501 atgattttta tattattgtc aaatgtgttt attgaagcag gctttgccaa tgcattaata
     7561 cgtaaaacaa atcgaactga gcaggatttg tcaacagcat tctattttaa tgtgttgatt
     7621 ggcatattgg catattgtat attatggatt ggttcaccgt ttatagctga ttggttcaaa
     7681 gaacctcttt tgtctttatt aattaggata tcaggtgtca atgttttatt aaattcttta
     7741 tgcatcgttc aaacagcctt gttaacagcg aatttagata ttcgtcggca aacaatcatt
     7801 aatttgtgtg ggcaaatacc tgcagggctg ataacagcta ttttggcgta taatgggttg
     7861 ggagtttatg ctctagtttt ccaaacaata atagcttcgt gcattagggt tattatgtta
     7921 tggctttata ctccatggag acctcaagaa aaatttaata gagaatcttt tctctctttg
     7981 tggaattttg ggagtaaatt actaggtgct aatttaatag gaacagcctt taatcaggtt
     8041 agttctgtgt taattggcaa atatatagga aaaagtgatt tgggatatta ctccaaagcg
     8101 tcaaatctat gtggaaatat tgatagcgtt tcatcgggag ttgtacagaa agtggcattg
     8161 cctatgttgt ctgaatttca aaaagacaaa gttctattat cagagaaatt tcgtgaaatg
     8221 atgcgtttgc ttatcatggg tatggcgcca ttgatttctt ttttctgctt tacagcatct
     8281 gacattattg taatactttg gactgaaaag tggattcagt gtgctttcgt atttcagata
     8341 cttatagtag gggcagcctt taatcctata ggacacatga gtcttagttt aatgcagaca
     8401 gttggaaatt ctgcattaat attaaaattg gaagtcccta agaaaattat ctattgcatt
     8461 tatttagcta taggtttctg ctatggctta gtcggtttgg ctgtcgccca agtattaatc
     8521 aatataacag gagctcttat taatatgtgg gcaacaaagc gtatcgtcaa atatagttat
     8581 atgcgacaaa tagtagatgt tttgggttat atggtgattg cttttattgt gggctatata
     8641 tggtttaata tgatacatac tggatatatg ttctttaata ttttattaat gtttatgttg
     8701 attgtgttta cttattttgc aatacttgtt atgattaagg atgcaatttt aattaaatat
     8761 gtaagaaaaa taattggact ctagctatta aacctgttta gatgattttt tttcttcttt
     8821 catattcgtg catcatccat tgtttctgta tcatagaaat gctacccatt ctatttcagc
     8881 ctcaaaggag taatatcctt ggagttagta tttgatgcgg aagagcacaa aaataacaat
     8941 atgcaatatt atgccatcaa ctatatgatt aaacatacga ttcttttatg aatattatct
     9001 gcgttttcat ctttttgata atcagcttac tattaattgt aaatttcaaa tgtactttca
     9061 tggtggtgtc tgcatgtagt atggtgttag gctgtatgaa tggagtggga ccttttggta
     9121 tgtaccaagc tgtttcaatt gctgcattca gtatttttat gttgcggtat ttttattgga
     9181 aggatatgcg aacttatccg ctcttgttca gctcaatatt attgattgta tcttatgtgt
     9241 tgagcaatca ttacgccgta taccgtcatt acggttcatt ggtttcctgc atagtggtag
     9301 atgtggcttc actgtttgta ttctatcaaa ttataagtaa aaatagccga tatatattta
     9361 tatatataag aacttgcgtt attttgtcgt tggttgttgg tgtatatacc ttggtagaaa
     9421 caataatttc cagtaaccat tatatgttca ttgtcaattc attggaacta tattctcaag
     9481 acatcatcgt agaggatata cgttttggca tgaaacgtgc gcaagctatt ttcggcatgc
     9541 acactacgtt aggaggtttc tccactatga tggctggact tttactttgg gtacgcttga
     9601 attgtacgct gtatgtaaag aagttgggaa agaaaaagct ttcaatagct attggcttga
     9661 tgattatagc cgtgtttctt acaggtacgc gtagtacgat agctggactg gccgtagtgt
     9721 taatgtcctt tttcagcttt aagcatataa agatgaagta tgtattcata gcaattgtct
     9781 cagtggtcat aggttttatg gctttggatg catatcttga taagataatc ctttcattta
     9841 ccgatacgga aagtgtagga ggaagcaata ctgatatgcg ttccatccag ttcgaactgg
     9901 cagctttgtt catgatgcag tctcctttct tgggaaatgg tatcagctat acatttgaat
     9961 atgtagccga taagtataag gagatgtgtg gtgcggaaag tttatggatt cccatcatga
    10021 tagacttcgg catattggga attacagcta ttattgtttt cattatacaa gtggggtatt
    10081 acattaagaa atactgcgaa attcgattgc tttttttctt attaggtata ttggtgttca
    10141 actcattgag ttctatacca gctttttctt ttacccaatt attttacctg tttgttataa
    10201 ttgcattttt aaaaaaatat caagaatcta tatgcaactc tccatcatca ttcccgtcta
    10261 taaagtagag aaatacatac gggatacatt gcaaagtatc tatcgtcaac agtacgacga
    10321 gaaccttttt gaggtgattg tgataaacga cggtacaccc gatgactcta tgcgtatagt
    10381 ggctgaattt acaaataagc atgccaatct gcatattatc aatcaaaaaa atcaaggatt
    10441 gagctgtgcc cgcaatgcgg ggttgaagat agcccaaggt gaatatgtat ggtttgtgga
    10501 cagcgacgat actgtgactg aggaaagtat agggaaggtc attgaatgca tagagagaag
    10561 taaggcggat gtgataggtt ttagcatact caaagtcagt gaagcgaata gagtgtctga
    10621 agtggaatca gccatttgga acgaacattg tcgtttctca tctaaccaaa ttgtctgtga
    10681 caaaagcatt ttattctcac ttcatacggg tgctgccgtt cgctatgttt acagacgggc
    10741 tttccttcaa atgaatcatc ttcgttttta tcccggcatc ctctacgagg accaagaatt
    10801 tcttcctcgc gtattcagct tagccaatag cttttacatt tcttcattca tttcctatcg
    10861 ctatcttttg cgctcatcag gctctatcat gtcgcagttc tcgttgcgct cattacgtga
    10921 tacgctcacc attgtgcgta gctatgagac atggctgcag gaagagataa aaggaaaatc
    10981 agccttgata aatgcttata tcaatgggtg cgtctttaat catacttact ggttgttgtc
    11041 gtttaaggct gttacctttc gggacgaaca gaaagaattt atgcgcgacc attatgctga
    11101 aatacggagg aagtgtctga cagcagggtg gaagtcgcta aaaggaaatt tcagactgac
    11161 gcgtgcggtc cgcctcctga tggtattcct tattccacat cacctcataa aatagataaa
    11221 cttaaattat taattataca ttcaagtaaa tgaaaagatt tttattactt cttctcttgg
    11281 cgtttgccat gtgggaactg caagcgcaaa ttccctactt tgccagtacg gccggtgatg
    11341 ggaaactcta tggatacact tcactgaaac tacgtcctgg tatcaataca caagagactt
    11401 ataccacatt ccaatacggc attggaaatt ctgtagcttt gggtacggat atctatacag
    11461 gagtaggttc aaattatatg ggattcctgg cccgttatgg tgtgtcactg agtaaatggt
    11521 tcaatgttgg tgcacagttt actccatcgt ttaatttaag ccataacttt gagtttggt
//
