LOCUS       c00051_gnlPro..        14260 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ECKOEBKE_51.
ACCESSION   c00051_gnlPro..
VERSION     c00051_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:15:20
            Original ID  :: gnl|Prokka|ECKOEBKE_51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14260
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14260
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4260]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4260
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14260
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14260
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..1325
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_1"
                     /sec_met_domain="Fer4_10 (E-value: 4.5e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.7e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 8e-51, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.7e-29, bitscore: 92.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.3e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAKPVVAK
                     GDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDEWEETI
                     DRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIINAVECE
                     PYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASSYAGIE
                     VVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKNKPLFE
                     RVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVNIEVPT
                     AKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETMEKERI
                     MDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             1331..2323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.6e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             2350..3066
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_3"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             3081..3665
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.8e-70, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             3688..4260
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.7e-63, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             4484..5518
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-51, bitscore:
                     167.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             5842..6141
                     /locus_tag="ctg51_7"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             6152..6514
                     /locus_tag="ctg51_8"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(6547..7377)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_9"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.8e-10,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2e-10, bitscore:
                     32.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             7616..9175
                     /locus_tag="ctg51_10"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             9347..11809
                     /locus_tag="ctg51_11"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             11841..12575
                     /locus_tag="ctg51_12"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             12585..12830
                     /locus_tag="ctg51_13"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
ORIGIN
        1 tttcaattgg tggagttcat ccacacgaaa ataaattgtc ggcacatcaa cctattatca
       61 cagcggaagt tcctgcaaag gctgttattt tgctggggca gcacattggt gcgcctgcaa
      121 aaccggttgt agcgaaaggg gatgtggtaa aggtaggcac taaaattgct gaacctgccg
      181 gctttgtttc ggcagcaatt cactcttcgg tcagtggtaa agtggcgaag attgatacta
      241 ttgtcgatgc cagcggttat gcgaaacctg ctatctttat cgatgtggaa ggcgacgaat
      301 gggaagaaac aatcgaccgt agcgccacac tggtgaagga atgtgaactt ccggcagaag
      361 agatcgtgaa gaaaattgcc gatgccggaa tcgttggtct gggcggtgct tgtttcccta
      421 cacaggtgaa actttgtcct cctccttctt ttaaggctga atgtgtgatt atcaatgctg
      481 tagagtgtga accttatttg actgccgacc atcagctgat gctggaacac gcggaagaaa
      541 tcatggtagg cgtttctatc ctgatgaaag cggtgaaagt gaacaaggca tttatcggaa
      601 tcgaaaataa taagcccgat gctatcgaac tgatgactaa agtagcttcc agctatgcag
      661 gcatcgaagt cgttcccttg aaggtgaaat atccgcaagg aggtgaaaag cagctgatcg
      721 atgcgatcac caaacgtcag gtggcgagcg gtgcgttgcc tatctctacg ggagcagtcg
      781 tgcaaaacgt gggaacggcg tttgccgttt atgaagctgt gcagaagaat aaaccgttgt
      841 ttgaacgggt gattaccgtg acgggaaagt cggttgcgaa gccgtccaac ttcctggccc
      901 gtatcggtac accgatgaaa cagttgattg acgcttgcgg tggtctgccc gaagatacgg
      961 gtaaggtgat cggtggcggt ccgatgatgg gtaaggcgct cgtaaatatc gaggttccta
     1021 ctgcgaaggg cagttccggc atcctgatta tgaaccggaa ggaagccaaa cgtggtgaag
     1081 ctcaaacctg catccgttgc gcaaagtgcg tgagtgcctg tccgatggga ctggaaccgt
     1141 acttactcgg agccttgtct gaaaacggag attttgaaac aatggaaaaa gaaagaatca
     1201 tggattgtat tgagtgcggc tcttgccagt tcacttgtcc tgccaaccgt ccgctgctcg
     1261 actattgtcg tctgggtaaa ggcaaagtag gagctatgat tcgtgcacgt caagctaaaa
     1321 aataacgaat atggaaaata aattaatcgt atcactatcg ccccacgttc atggcggaga
     1381 cagcgtacag aaaaatatgt atggcgtgct aattgcactg attccggctt ttctggtgtc
     1441 tctctatttc ttcggactgg gtgccctgat tgtcacggct acttccgttg cggcttgttt
     1501 gttcttcgaa tgggcgatcg gaaaatattt aatgaagaaa ccgaccacca ccatctgcga
     1561 cggctctgcc atcatcacag gtgtgttgct ggcatttaat ttaccgtcta acttgcctat
     1621 ctggattatc atcctcggtg cactgtttgc tatcggtgta ggtaagatgt ctttcggcgg
     1681 attaggctgc aatcctttca acccggcatt ggcaggccgc gtattcctgc tgctttcttt
     1741 cccggtgcag atgaccagct ggccggtagt cggacagttg accgcttata cggatgctac
     1801 caccggtgcc actccgctgg ccttgatgaa gcaagccatt tacggtgaca ctgccgcttt
     1861 aagccagatt ccggacgcat tgaccttgct gatcggacag aatggcggat gcttgggtga
     1921 agtgagtgcg ctggctctgc tgatcggact cgtttatatg ctctggaaga aaatcatcac
     1981 ctggcatatt cctgtgtcta tcctggctac tgtgtttgtc tttgcaggca tcatgcacct
     2041 ggcagatccg gaaaaatacg tttctccggt attgcagttg ctttccggtg gtctgatgct
     2101 gggtgctgtc tttatggcaa ccgactatgt gacttctccg atgagtaaga aagggatgct
     2161 gatctatggt gtatgtatcg gtctgctgac ggtagttatc cgtctgttcg gcgcctatcc
     2221 cgaaggtatg tcgttcgcca tcctgattat gaatgcgttc actccgctga ttaacaccta
     2281 ttgtaaacca aaacgctttg gggaggtagc gaagaagaaa tgaaaaagtt agaatcatct
     2341 ttaaagaata tgttgctggt acttacggga gtgactgcta tttccgttgc gttgctggct
     2401 tatgtaaatg aactgacaaa aggccccatt gccgaagcga acgcgaagac actgaacgag
     2461 gccttgaaaa aggttcttcc cgaatttacc aataatccgg tagcggaaag cgatacgatc
     2521 ttcagtgaga aagatggaaa gaagaatgtt gactttatcg tttatccggc taagaacggt
     2581 gaagagcttg taggtacggc tgttgaagct aaatcaatgg gatttggcgg tgaactgaaa
     2641 gtgctggtag gctttaatgc cgaaggaaaa atctataact actctctgtt ggctcacacg
     2701 gaaactccgg gattgggctc taaagccgac aaatggttcg gagcgtatga tcctgcgaaa
     2761 ggagaaaagg cagtatctca cgaagagagt acgaaatcta ttttgggtat gaatccgggt
     2821 gaagctccgt tgaccgtcag taaagatggg ggagcagtgg atgccatcac agcttctacc
     2881 attacttcac gcgctttctt gaatgccgtg aatgctgctt atcaggccta taaggccgaa
     2941 ggcggggaag tgaatggtgt aaccggtgct tctcaaaaag cgaaaggcgc ggacgcagat
     3001 gctgctgacg ctgctacggg agctacgatc aaagttgaac taactgattc agtcagtgct
     3061 aaataagaaa ggagacagat atgaataact ttaaagtaat gatgaacggg attatcaaag
     3121 agaatcctac gtttgtactc ctgctcggta tgtgtcctac attgggtact acatcatcgg
     3181 ctatcaatgg tatgggtatg ggactggcta ccatgttcgt attgatctgc tcgaatgtgg
     3241 tgatttcttt aataaagaac ctgattccgg acatggtgcg tatcccatcg tttattgtgg
     3301 tgatcgcatc cttcgtgacc ttgcttcaaa tggtgatgca ggcttacgtg ccgggactgt
     3361 atgctacact cggtcttttc attccgttga ttgtagtgaa ctgtattgta ctgggacgtg
     3421 ccgaagcctt cgctgccaag aataacgcag ttgcttctat gttcgacggt atcggtatgg
     3481 ggcttggctt taccatcgcc ctgactttac tgggtgctgt ccgcgagttt ttgggaaccg
     3541 gtaaaatctt cgatttgacc atcatgccgg aagaatatgg aatgttggtg tttgtattgg
     3601 ctccgggcgc tttcatcgct ttgggatacc tcattgcgtt gattaacagt ttcaagaaag
     3661 cctaattcaa ttaaataaga aaagaatatg gaatatatat tgatatttat ttcggcaatc
     3721 tttgtaaaca acatcgtgtt gtcgcagttc ctgggtatct gtccgttcct gggcgtatcc
     3781 aagaaggtgg aaactgcgat gggtatgagc gctgcggttg ctttcgtgtt gaccatcgct
     3841 accatcgtca ctttcctgat tcagaagttt gtactggatg ttttcggact gggatacctg
     3901 cagacgatta catttatcct ggtgattgcc ggattggtgc agatggtgga aatcatcctg
     3961 aaaaaggtgt ctccggctct gtatcaggcg ttgggtgtgt tcttgccgct gattacaacg
     4021 aactgttgta ttcttggtgt cgctatcctg gtgattcaga aagactatga cctgctgaca
     4081 ggtgttgtgt acgcgttttc tacagctatc ggcttcggtc tggcactggt gctttttgcc
     4141 ggattgcgcg aacagatgag tctcgtgaaa gttccgaaag gaatgcaagg aactccgatt
     4201 gctttgatta ccgccggttt gcttgctatg gcattcatgg gattctccgg cgtggtgtaa
     4261 ggatttacag ttgataatta aataggggat tggaagctct gctgtgtggc gacatacagg
     4321 ttagagtttc caattctttt tatacctaaa tgctaccaaa tcgtacctta attacttttc
     4381 agcaaataaa tttatggcag attattgcaa ttccatttta tttccataca tttgtaactc
     4441 aaacaataat aagccgagaa actaaccatt ttttataaag tatatgaaag aaagaatttt
     4501 agtaacaggc gggacaggat acattgggtc tcatactgtt gtagaactac aaaacagtgg
     4561 atatgaagta atcatcatcg ataatttatc aaattcaagt gccgacgttg ttgacaatat
     4621 agagaaagtt tccggtattc gcccagtttt tgaaaagctg gactgtttgg actttgccgg
     4681 tctggatgca gtatttgcaa aatataaagg aattaaggca atcattcact ttgcagctag
     4741 caaagcagta ggagagtcgg tacaaaaacc gttgctttac taccgtaata acctggtttc
     4801 tttgattaac cttctcgaac tgatgccaaa acatggagta gaaggtattg tgttctcttc
     4861 ttcttgtaca gtatacggtc agccggacga gctgccggta acggaaaaag ctccgatcaa
     4921 gaaagcggaa tcaccttatg gaaataccaa acagatcaat gaagagatta ttcgtgatac
     4981 ggtagcttca ggtgctccga tcaatgcgat catgttgcgc tatttcaacc cgattggcgc
     5041 gcatcctact gcattgcttg gtgaactgcc taacggggtt cctcaaaacc tgattccata
     5101 tctgacccag acagccatcg gtatccgtga gaaacttagc gtgtttggtg acgattatga
     5161 tacaccggac ggttcttgta tccgtgactt tatcaatgtc gttgacttgg ctaaagcaca
     5221 cgtgattgct atccgtcgta tcttggaaaa gacacaaaaa gaaaaagtag aagtatttaa
     5281 tattggtaca ggacgtggtg tttctgtatt ggaattaata aatggctttg aaaaagccac
     5341 tggcgtaaaa ttgaattatc agattgtcgg acgtcgtgca ggcgacattg aaaaagtttg
     5401 ggctaacccg gattttgcta ataaagagct gggttggaaa gccgtagaaa ctttagaaga
     5461 tactttacgc tctgcatgga actggcagct gaaactccgt gaaagaggga ttcaataaaa
     5521 gagaaacttg ttttaaataa cataaaagtt taaacaaatc gtgcatgcga tttgtttaat
     5581 tgatgctaat cgacctgaag ctgtttatga gtatgcgaat atacgtagat agtacttatg
     5641 cctccccggc atagacagga aagattgcat agtagttttg tcgtgtttta ttttgtgttt
     5701 gtgttgtgac ggtactacga cgtgagtcgt ggtaccgttt tttggtacgc ccagcatgga
     5761 tgttctgttt tataaaatat ttagcactaa ttcttttgtt atccaaaatt attttgtaat
     5821 tttgtatcaa atgaataaga tatgagagta gtatcacata agaaattgaa agatttctac
     5881 gagacgaaag ggtgtgaaga ttcacgtgtt gctttagaac gttggtatga tatagcggaa
     5941 aaagcagaat ggcggaattt gtctgatata aaagcggatt ttctatcgac tgattatgtg
     6001 ggcaatcaac actatgtttt taatatcaga gggaacaact atcggctggt agtggttgtt
     6061 aaatttacgg tgggatacat ttttgtccgt tgggtgggaa ctcataaaga gtatgataaa
     6121 atagattgtt caactatata atataataga tatgactaaa ataacgaaag aacaatacga
     6181 atttgcattg gcaagagtcg aagaacttct gcctttggtg gacgacagca ctcctgcaaa
     6241 tgacaagagc atggtggagc tttctgttat gtctgatata gtgattgcgt atgagaagga
     6301 acattttcct atagaaaaac caaccgtagc agaattgata gaattgtccc ttgaagaaaa
     6361 ggggatgaca caaaaacagc ttgccagtga aataggggtt agcccttcac gcgtgaatga
     6421 ttatatttcg ggtcgctcgg aacctacttt aaaaatagct cgcttgcttt gccgggtact
     6481 caatatacac cccgctgcca tgttgggatt ttgaaaaaat agtcaaaaca taattgttag
     6541 tgagatttat ttgtttaatg tacctttgaa gcagaataca tcagttcccc aatcaatttc
     6601 cggtaagacg aatccgggag caaacagccc gaatacggat gagccggagc cgctcatgga
     6661 tgcgtagatt gctccttgat gatagagttc ttctttgatt tctccaatga cgggatgttg
     6721 cgggaataca cttgcttcga aatcattgat taacgtatcc ttccattctt gtacaggacg
     6781 ctggattgcc tccctaaccg gatatttcgg acgatgggga tgaatgtttg aaaaggcttc
     6841 ccgggtggaa acaaaaacat tcggttttat aatcatgatt tggtagccgt ttaatgaaag
     6901 ttcgaccggg gagaagatgt ttccaattcc ctcggcaaat atcggtctgt ttttgataaa
     6961 gaaagcgcag tctgctccca aagtggcagc gtatacttcc aattgttctt cggatactcc
     7021 cagctgataa tgatcgttga gcaactttag catgaaagcg gcatccgatg atcctcctcc
     7081 cagtccggct cctgaaggga tgtgcttgta taagtggatt tcgacaggag ggagatgaaa
     7141 ttccttatcc atcaataaat aggcttttac taccagattg tcttcagggt taccggctat
     7201 ttccattcca tgttggtgga gagtgaattt tcggtcagcg ttaggggagg tacggatttc
     7261 cagtgcgtct tccagagcca ccggatagaa aactgtttcc agattgtggt atccgtccgg
     7321 gcgtttttcc gtgatggaaa gtcccaggtt tattttgata ttgggaaaag caatcatatt
     7381 tctatttact attttactat ttactattta cagtgcttca cattacaatt aatcatagct
     7441 ggataatgtg aatcgggagc aaagttacta aaatcttcat ttttccttat tcattcttcg
     7501 tgattatatt ctatctttgt cgtctcgact ggaagaattc cgtgataaat gtgataatag
     7561 agtctgtcca gtcgtaaaat aataaatagt aaatcgtaaa atagtaaata tctcgatggc
     7621 cgaacagaaa agaaataccc gcaattcaaa gtctactaaa atacaaccgg taaatgatta
     7681 tggtcgtatt cagccgcagg cgcctgaact ggaagaagca gttttgggag ctttaatgat
     7741 tgaaaaggac gcttattcat tggtgagtga aattcttcgt cccgaatcat tttacgaacg
     7801 ccggcatcag ttgatttatt ctgctatcgt cgatcttgcg gtgaaccaga aaccggtgga
     7861 tattctgact gtaaaggaac aacttagtaa acgcggagac ttggaagagg tgggaggtcc
     7921 cttctatatt actcaattga gtagtaaagt ggcttcatcc gcacatattg aataccatgc
     7981 ccgtattatt gcacagaaat cgctggcgcg tgagttgata acgtttacga gcaatatcca
     8041 gagtaaagcg tttgacgaga ccctggacgt ggacgacttg atgcaggaag cggaaggtaa
     8101 gcttttcgag atctcacagc agaatatgaa aaaagattat acgcagatca atccggtgat
     8161 tgacgaagcc tataaactaa ttcagaaagc tgcggctcga accgatggtt tgagtggtct
     8221 ggagagtggt ttcacgaaac ttgataagat gacttcgggt tggcagaatt ccgaccttat
     8281 tattatagct gcccgtcctg ctatgggtaa gactgctttc gttctttcaa tggctaagaa
     8341 tattgcggtg gattaccgga acccggtggc gttgttctcg cttgaaatga gtaacgttca
     8401 gctggtgaac cgtttgattg cgaatgtctg cgagattccg agcgagaaaa tcaaaagcgg
     8461 gcagttggca aattatgaat ggcaacaact ggactataaa ctgaagaatc tgatggatgc
     8521 accgctttac gtggatgata cgccgtctct gtctgtgttt gaacttcgaa ccaaagcgcg
     8581 tcgtctggta cgcgaacatg gggtgcgaat catcatcatt gactaccttc agttgatgaa
     8641 tgcgagtggg atggcgtttg gtagtcgtca ggaagaggtt agtaccattt cccgttcgtt
     8701 gaaaggattg gcgaaggagt tgagtattcc gattatcgca ctgtcacagt tgaatcgtgg
     8761 tgtggaaagt cgtgaaggta ttgacggtaa acgaccgcag ttgagtgacc ttcgtgaatc
     8821 gggagccatc gagcaggatg ccgatatggt gtgctttatc catcgtccgg aatactataa
     8881 gatatttcag gatgatcgtg gtaatgacct gcgcggtatg gcggaaattg taatcgccaa
     8941 gcatcgtaac ggtgcggtag gcgaggtgtt gctccgcttt aagggtgagt ttacccgttt
     9001 ctctaatccg gaggacgata tggtgatccc gatgccgggc gagcctgcag gagctatgtt
     9061 aggatcgaaa atgaatacag gtaatgctgg ttccatacct cctcccgcac ctgattttgc
     9121 accgcagacg gagaatccat tcggagcacc gggagatgga ccgttaccat tttagttgat
     9181 agttgataac tgatagtgaa aatgctctgc gcaacatttc ttctatctgt atgttattcc
     9241 gcatggtaac tatcaactat aaactttttt atctaacctt ctcggtcaac cgaaaaatct
     9301 tattaacttt gcaaatcttt ttgagaaaca ataaaaaatt aaatatatga atatctctta
     9361 taactggctg aaagagtatg tcaacttcga cctgacgccc gatgaaacgg ctgctgcgtt
     9421 gacttctatc ggcttggaaa caggtggtgt agaagaagtg caaaccatta aaggtggttt
     9481 ggaaggactg gtgatcggtg aagtgctgac ctgcacggaa catcctaatt ctgaccattt
     9541 gcatattact actgtcaatc tgggagacgg tgaaccggta cagattgttt gtggtgcccc
     9601 gaatgtggct gccggacaga aagtggtggt agctacttta ggtacaaaac tttatgacgg
     9661 tgacgaatgt tttaccatca agaaatcaaa aatccgtggg gtggaatcta ctggtatgat
     9721 ttgtgccgaa gacgaaatcg gtatcggtac ggatcatgca ggtattatcg tattgccgga
     9781 aaatgctgtt ccgggtacgc ttgccaagga ttattataat atcaagagcg actatgtgct
     9841 tgaagtggac attacgccta accgtgcgga cgcttgctct cactatgggg tggctcgtga
     9901 cttgtacgct tatctgattc agaacggcaa acaggctact ttgcaacgtc cgtcggtaga
     9961 cggttttaaa gtggaaaacc atgacttgaa tattgaagtg aaggtggaaa acagcgaagc
    10021 ttgtccgcat tatgccggtg ttacggtgaa aggtgtcact gtgaaggaaa gcccggaatg
    10081 gctgcaaaac aaattgcgtc tgatcggggt gcgtcctatt aataatgtag tggatattac
    10141 taattatatc gttcatgctt tcggtcagcc gttgcattgc ttcgatgccg gaaagataaa
    10201 aggcaatgaa gtaattgtaa agacaatgcc ggaaggaacc ccgttcgtta cgctggatga
    10261 ggtggaacgt aaattgaacg aacgcgacct gatgatttgt aacaaggaag aggccatgtg
    10321 tattgccggt gtattcggcg gactggactc cggttctacg gaagctacga cagatgtatt
    10381 cattgaaagt gcttatttcc atcctacatg ggtgcgtaag acagcccgcc gtcatggctt
    10441 gaatacggat gcttctttcc gtttcgaacg cggtatcgat ccgaacagtg tgatatattg
    10501 cttgaaactg gctgctttga tggttaaaga actggctggc ggtacgattt cttctgaaat
    10561 aaaagacgtg ttcactactc ctgcacccga ttttatagtt gatctggctt atgagaaagt
    10621 acattctttg gtaggaaaag taattccggt agagacaatc aagagcattg tgaccagcct
    10681 ggaaatgaag atcactaatg aaacggcgga agggctgaca ttagctgttc ctccttatcg
    10741 tgtagacgtg cagcgtgatt gtgacgtgat tgaagatatt cttcgtatct acggatataa
    10801 taatgttgaa atcccgacta cactgaactc cagcctgact accaaaggtg aacatgataa
    10861 atcgaataaa ttgcagaacc tgattgcaga gcaattggtg ggctgcggat ttaatgagat
    10921 cctgaacaac tcattgacgc gtgctgctta ctatgatggc atggagactt atccgtccaa
    10981 ccacctggtg atgttattga atccgttgag tgcggatttg aacgctatgc gtcagacttt
    11041 gctgttcggt ggactggaaa gtattgctca taatgcaaat cgtaagaatg ctgatttgaa
    11101 gttcttcgaa ttcggtaatt gctatcattt cgatgctgac aagaagaatg aagagaaggt
    11161 attggctcct tactcggaag attatcactt gggcttgtgg gtaaccggta agaaggtttc
    11221 caattcatgg gcacatgcag atgagaacag ttcggtatat gaattgaagg cttatgtaga
    11281 aaatatattg aagcgtctgg gactggattt gcacaatctg gttgtcggta atctgacgga
    11341 cgatattttt gctgccgcac tttctatcaa tacgaagggt ggtaagcgtc ttgcttcctt
    11401 cggtatcgtg actaagaagc tgttgaaagc atttgatatc gacaatgaag tgtattttgc
    11461 cgacttgaac tggaaggaac tgatgaaagc tatccgttct gtgaagatca gctacaagga
    11521 aatctccaag ttccctgctg tgaaacgtga cctggcattg ttgcttgaca agaatgtgca
    11581 gtttgccgaa atcgaaaaga ttgcttacga aacagagaag aagctgttga aagaagtgga
    11641 actcttcgac gtgtacgaag gtaagaatct ggaagcaggc aagaagtcgt atgcggtgag
    11701 cttcctgctt caggatgaga gccagacttt gaatgataag atgattgata agatcatgtc
    11761 gaaactggtg aagaacttgg aagataagct gggtgccaaa cttagataaa cttaaaattt
    11821 caatctaaaa atataaacca atgggaagag catttgaata tagaaaggcc gctaaactga
    11881 aaagatgggg ccacatggct aaaacattta caagactggg taaacaaatc gcgatagctg
    11941 taaaggcagg cggtccggaa cctgaaaata acccgacttt gcgttcggtg atcgctactt
    12001 gtaagcgtga aaatatgccg aaggataata ttgaacgtgc tatcaaaaac gcaatgggta
    12061 aagaccagag cgactacaag agcatgactt acgaaggata cggtcctcac ggtattgctg
    12121 tatttgtgga tacgctgaca gataacacaa cccgtacggt ggctgacgtt cgttcggtat
    12181 ttaataagtt tggcggtaat ctcggtacaa tgggatctct cgcgttcctg ttcgaccaca
    12241 aatgtgtatt cactttcaag aagaaagacg gattggatat ggaagaactg attctggatc
    12301 tgatcgatta tgatgtggag gatgaatacg aagaggatga tgaagaagga acaatcacta
    12361 tctatggtaa tcccaagagc tatgccgcta ttcagaaaca cctggaggag tgtggctttg
    12421 aagatgtcgg tggagacttc acttatatcc cgaacgacat gaaagaggtg actccggaac
    12481 agcgcgaaac attggataag atgatcgaac gtttagaaga atttgacgac gtgcagactg
    12541 tttataccaa tatgcagccg gaagagggag aataagacaa ggttatggaa tatgtgtata
    12601 gaacccaggg aacttgtagc accaacatcg aactgaatgt ggaagatgga gtggtgaaag
    12661 aagttgcttt ttggggagga tgtaatggta accttcaagg tatttcccgc cttgtgagag
    12721 gaatgaaggt agcggatgtt atcgcaaaac ttgaaggagt gcattgtggt ggcagaccga
    12781 cttcatgtcc tgaccaattg tgtcgtgcat tacatgagat gggatattaa tcgacttctt
    12841 ttatttttgt aaaatttgat atttttcaag accttcggca atttattttg tcgagggtct
    12901 tttttttgtg ggaatccata ggggggggat ccgggtgttg tttacttact tgtcggtatt
    12961 ttgaactaaa attgaccttc actcgttatt tataagtata tttgtaaggt taaaactatt
    13021 atgcaaaaat gaagaatatt tttcaagact taaaacgcaa agatcataaa cgctatctgg
    13081 gtggactgga tgtttttaaa tatattggtc cggggcttct agttacggta ggatttattg
    13141 atccgggaaa ctgggcttct aacttcgccg ccggttccga atttggctat tccttacttt
    13201 gggtggttac attgtccact attatgctga ttgtgcttca gcacaacgtt gcccacctgg
    13261 ggattgttac cggactttgc ctttcggagg cggccactaa atacactccc aaatgggtgt
    13321 cgcgacctat tcttggtacg gcggtactgg cgtcgatttc tacttcttta gcggaaattc
    13381 tgggaggtgc cattgcgttg gaaatgctct ttgatattcc tattatatgg ggagctgtgt
    13441 tgactacgct ttttgtctct atcatgcttt tcactaattc gtataaaaag atagagcgtt
    13501 ccatcattgc atttgtctct gttatcgggc tttcgtttat ctatgaactg tttctggtgg
    13561 aaatagactg gccggctgcg acagcagggt gggtgactcc ttcttttccg aaaggaagta
    13621 tgctgattat catgagtgtg ttgggagcgg tagtgatgcc tcataatctg tttcttcatt
    13681 cggaggtgat acagagtcac gaatataata agaaagatga tgcttctatt aagaaggtct
    13741 tgaaatatga gttgtttgat actcttttct caatgattgt cggctgggcg attaacagtg
    13801 ccatgattct tctggctgcc gctactttct ttaaaagcgg tattcaggta gaggaactgc
    13861 aacaggctaa gtcattgctc gaacctttgt tgggaagtaa tgctgccatc gtatttgcac
    13921 tggcattgct gatggcgggt atttcatcca ccattacgag cggaatggcg gcaggttcca
    13981 tctttgcggg tattttcggt gaatcgtatc atatcaaaga cagccactcg caggtaggag
    14041 tccttttatc tctgggaatt gccttattgc tgattttctt tattggagat cctttcaaag
    14101 gattgattat ttcgcagatg atacttagta ttcaattacc tttcacggta tttttgcagg
    14161 tgggactgac gtcttcccga aaggtgatgg gagattatgt caatagtcgt tggagcacgt
    14221 ttgtgttgta ttcgattgcc attattgttt cggtactgaa
//
