LOCUS       c00042_gnlPro..        16839 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFLEBEAI_42.
ACCESSION   c00042_gnlPro..
VERSION     c00042_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:39:53
            Original ID  :: gnl|Prokka|NFLEBEAI_42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 230892
            Orig. end    :: 247731
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16839
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[240892:243918]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13026
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16839
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16839
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             733..2433
                     /locus_tag="ctg42_193"
                     /transl_table=11
                     /translation="MKKVLLILACGIATQLSYAQATPKWADKAKKAVFSIVTYDKDNKI
                     KNTGNGFYINENGTALSDYTLFEGAERAVIINADSKELPVLRILGANSMYDIVKFNTEA
                     DKKTIALKSASQPASVGETVYLLPYSTQKAATCQTGTVTKVDTIGDKAYYYTLAMTTNE
                     KTVSCPIMNANGEVLGLIQKNASDEAKESYAIGATYGASLSITALSLNDMSLNKIGIKK
                     GLPETEDQALVYLFMASSQQNQNEYITTLNDFLEQYPNSADGYIRRATTYMGFSDDEHN
                     ALADADLKKALEVTTNKSETQYNIAKLIYSYIISLGDKKPYGDWSYDKALSIIHDAMQA
                     DNQPIYTQLEGDILFAMKKYPEAYAAYEKVNQSSIASAATFYSAAKTKQLIEGTDMNEV
                     IALMDSAVARFTKPYTSEAAPYFYERAEIKAQTGKYREAVIDYDTFYDAIGGRVTAAFY
                     LQREQAEIQCKMYQQAINDINKAVEMTPEDVAMWVEKGSVHLRVGQHNEAIEALEKAIS
                     LDPKAAAAYRMLGYCQIQLKKNKEACANFAKAKELGDEVVDGLIQKYCK"
     CDS             complement(2572..3876)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_194"
                     /sec_met_domain="ATP_bind_3 (E-value: 4e-51, bitscore:
                     167.0, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHWNIQKYIEEKQLFTLHDKVLVALSGGADSVALLRVLLVLGYH
                     CEAAHCNFHLRGEESDRDERFVNELCKGLGVALHVTHFDTVTYASRHHVSIEMAAREMR
                     YDWFEQLRKERGGAVIAVAHHRDDSVETFLLNLIRGAGINGLKGISPHNGCIVRPLLEV
                     SRQDILDYLRCLRQGYVTDSTNLQDEYMRNKIRLNILPMLRELNPSVSESIAETSRRLT
                     DVSLIYNKEIEAGKERVMEKSGHILISRLMEESAPAALLFEILHPLGFNSVQAGDVFRS
                     LSAQSGKRFVSAGWEVLRDRTELIIRRRKLADEEVEENVPPFRLAMETQEIMPDFVIPK
                     NKDTACLDADKVVLPLTVRKWRQGDKFVPFGMKGKKKISDYLTDRKFSLFQKENQYVVC
                     SAGQIVWLVGERSDDRFRVTEDTKRVLIIQQLWDK"
     CDS             3997..6465
                     /locus_tag="ctg42_195"
                     /transl_table=11
                     /translation="MRLSELRTGEKGVIVKVLGHGGFRKRIVEMGFIKGKTVEVILNAP
                     LKDPIKYRLLGYEISLRRQEADMIEVVSEQEARTMQNPYHGSITEDVPVPESELVALAK
                     GKRRTINVALVGNPNCGKTSLFNIASGAHEHVGNYSGVTVDAKEGFFDFQGYHFRIVDL
                     PGTYSLSAYTPEELYVRKHIIEETPDVIINVVDSSNLERNFYLTTQLIDMNVRMVIALN
                     MYDELEASGNKLDYTQLSQLIGVPMVPTVCRRGEGVDKLFHVIIGIYEGGDFLSQKGEI
                     RSEILEDLRDWHKTYVPDHEFGSHKEEEDARPRGYMRHIHINHGPELERSIEEVKKAIS
                     QNEDIRHKYSTRFLSIKLLENDREIENFISTLPNGKEIIAIRNKETLRIRKVMNEDSEQ
                     AITDAKYGFITGALKETFTDNHLEKEQTTRVIDSIVTHRIWGYPIFFLFLYIMFEGTFV
                     LGDYPMQGIEWLVDQLGNLIRNNMAEGPLKDLLIDGIIGGVGGVIVFLPNILILYFFIS
                     ILEDSGYMARAAFIMDKIMHRMGLHGKSFIPLIMGFGCNVPAIMATRTIEDRKSRLITM
                     LVNPLMSCSARLPIYLVMIGAFFPNCASFMLLCIYTAGILLAVIMARIFSKFLVKGEDS
                     PFVMELPPYRMPTSKSIMRHTWEKGAQYLKKMGGIIMIASIIIWFLGYYPRHDAHESVA
                     EQQENSYIGQIGKAIEPVIKPLGFDWKLGIGLISGVGAKELVVSTLGVLYTNEGDVENV
                     NLSDRIPITPLVALAYMLFVLIYFPCIATFAAIKQESGSWKWAIFAAGYTTGLAWLVAF
                     TVFQIGSIII"
     CDS             complement(7030..7674)
                     /locus_tag="ctg42_196"
                     /transl_table=11
                     /translation="MKADLATIRREYTKGGLKRSDLPDNPLVLFTKWLQEAIDAEVNEP
                     TAMLVGTVSPEGKPAIRTVLLKDLHDGKFIFYTNYGSRKGKHLAHNPSISISFVWHELE
                     RQIHIEGIAAKVSPQESDEYFRKRPYKSRIGARISPQSEPIESRIQLIRDFVKETTRWI
                     GKEIDRPEYWGGFAVMPVRVEFWQGRVNRLHDRFLYMLQSDGVWKIERLAP"
     CDS             8136..9230
                     /locus_tag="ctg42_197"
                     /transl_table=11
                     /translation="MKILLIGEYSNIHWTLAKALRNMGHRVDVLSHSNLWLNNSDYLYP
                     NRSSIRWGVLKNTFNLLKTLPQLRGYDVVQLVNPYFLELKPELLQYVFQYLKKNNKKIF
                     LGGFEYDFYWIYMCLNKNALRYNDFYANGTFRDTIDNKMAIINWMHGFRGKLNRIIANN
                     CNGIITSLYESYLAYQPYFSGKTKYIPFPIESLPHPQIPFKKIEKVKFYISLKHHREEW
                     KGKDELYSALYKLYYRHPSACEIKQTVFTPYDECEHFMDGCDVMLDQLYSYSPGLNALY
                     AMSKGIVVVGGAEEEHYNLLGEDRLRPIINVRPEGNDIYNKLESLLANTNKISQLSADS
                     IEYIKKHHCPIKVAKECLDFWEKN"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_198"
                     /sec_met_domain="Gly_radical (E-value: 1.4e-46, bitscore:
                     151.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMNKVFKDGLWSKEINVSDFVHTNITPYEGDASFLAGPTERTKK
                     VWNECLKALEEERANNGVRSLDNVTVSTITSHKAGYIDRENELIVGLQTDELLRRAIKP
                     YGGIKVVEKACHENGVEVDEKVKDIFTHYRKTHNDGVFDAYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLHNITSPMTDARIRLREEVAEQIKALKEIK
                     ILGEYYGLDLGRPATNAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYIQYDLDH
                     GKIDESFAQELVDQFIIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKEFCAQVSIDTSSIQYENDTLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKDIPVLTGDLL
                     NFEEVWSNYKKVLMQIARVYNDAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYGKVRAKRNDIGLTEGFDIENAYPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKHPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDAQDGISNTFSIVPKSLGVDQETRIENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFIKLSREHQLEVISRSFHERM"
     CDS             12298..13026
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 77.8;
                     E-value: 3.2e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_199"
                     /sec_met_domain="Radical_SAM (E-value: 3.8e-27, bitscore:
                     89.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIDTKGE
                     STETTIDEIVRMAVSQKAFFGKKGGVTFSGGEPTLQAKALIPLFQRLKEQSIHICIDTN
                     GSIWNEEVKELLQWTDLVLLDIKEFNNVRHRQLTERSNEQTIRTAGWLEKNGKPFWLRY
                     VLVPGYSSFEEDIRALGEHFKNYQMIQRVEILPYHTLGVHKYEAMGKEYKLNGIKENTL
                     KQLETAKTLFGEYFNTVYLN"
     CDS             13128..13877
                     /locus_tag="ctg42_200"
                     /transl_table=11
                     /translation="MKRLLLLCLTYIMCVGNHQMAAQDSSESPGIFNSLAVGVSASTTG
                     IGIDVASPIGSYLAVRAGVSFMPNFTYSTDVDVDIEGSYEGNIPTSIDVEGGMGRTAGE
                     ILLNVYPFKSSSFFVCGGAYFGGGKLIKIKGHSDELAELIKEGQEVGIEIGNYRIPVDQ
                     NGNISGGLKVSSFRPYLGLGFGRAIPKKRIGFMFEMGVQFHNTPKVYTNNGDLSDLTAE
                     ADNDFTDIIDKLTVYPVLKFRLCGKIF"
     CDS             complement(13956..14543)
                     /locus_tag="ctg42_201"
                     /transl_table=11
                     /translation="MSSREDILQSIRRATHVKYEKPDLKPLEDMALTYPSKVEQFYLIM
                     KQVGGEAILLEKEEDVNDFIKKAYPGAKRIASNLKTITCATFNPDDVEDPAELNGTDLA
                     VIDGKIGVAENGAVWIEQDVKQRAIYFIAEKLVILLNKNKIVNNMHEAYKLIDTGEYGF
                     GTFISGPSKTADIEQALVMGAHGARDVMVVLI"
     CDS             complement(14546..15913)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_202"
                     /sec_met_domain="Fer4_8 (E-value: 2.9e-11, bitscore: 37.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.7e-05, bitscore: 16.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKHSKAAAEFLKNKKQAAWHDETLWLVRAKRDRLSKEVPEWEE
                     LRNMACATKLYSNSHLDELLVEFENNARANGAHVYWAKDADEYCNIVYNILNQHGVKHF
                     IKSKSMLAEECELNPFLENKGIEVVESDLGERILQLMHLKPSHIVLPAIHIKREQVGEL
                     FEREMGTEKGNFDPTYLTHAARKNLRQKFIHAEAAMTGANFAVASTGEIVVCTNEGNAD
                     MGTSQPKLQIAAFGMEKIVPDRESLGVFTRLLARSATGQPITTYTSHYRKPREGGELHI
                     IIVDNGRSKILADQKHIKTLNCIRCGACMNTCPVYRRSGGYSYTYFIPGPIGINLGMLK
                     APLHYYDNVSACSLCYSCSFVCPAKVDLAEQIYLWRQDLDKLGKADRMKRVMSGGMEFM
                     MNRPLIFNMALKWAPLVNGMPRFLIYNGLNDWGKGREMPKFAKESFNEMWKKGKVK"
     CDS             complement(15910..16650)
                     /locus_tag="ctg42_203"
                     /transl_table=11
                     /translation="MKVGLFIPCYINAVYPQVGIASYKLLKSLGVDVDYPLNQTCCGQP
                     MANAGFENKAVDLARHFDEQFKNYDYIVGPSASCVVFVRDNYSRLLKEDKHRCASEGKI
                     YDICEFIHDIVRPSSLKAKFPHKVSLQNSCHGVRLMKLSSASELNIPYFSKLRDLLSLV
                     EGVEVVEPERKDECCGFGGMFAVEEDAVSVQMGHDKVMRHIATGAEYIVGADSSCLMHQ
                     NGIIARDKLPIKTLHIVEILAAGL"
ORIGIN
        1 ataaagtatt ggtgaagaaa gatatacaga gcgaactgtc caaagaactg tttgcctgtt
       61 tgaaaaatac cctcatccct gttcagcgtg tacccgtgga gcgtattaac cgtatcaccc
      121 ggaaaaacca tcagggagtt gtagcattca tctcctctgt cacctaccag aaaacagaaa
      181 atctggtacc tttcttgttt gaagaaggaa aaacaccctt attcgtcatg ctggatggaa
      241 ttaccgatgt acgtaacttc ggagccattg cccgtacctg cgaatgtgcc ggtgcagatg
      301 ccattattat tccctcgaaa aacagtgtca gtgtcaatgc tgacgcaatg aaaacatccg
      361 caggagctct gcacactctt cccgtatgtc gcgaacaaag tttgactaat accatcaagt
      421 atctgaaaga ctgcggattc aagattgtag cagctacgga aaaaggggat tatgattaca
      481 ccaaagcaaa ctataaagac cctgtatgta tcattatggg agccgaggac acaggtgttc
      541 cctacgagca cctttctctg tgcgatgaat ggatcaaaat accgttaatg ggtaaaatag
      601 aatcactgaa cgtatcggtt gccgcaggta ttctgattta tgaagctgta aaacaacgcg
      661 gcttcacaga agacaagacg gcatccgctt tataaaatac cgtatcatcg ttaacaaaca
      721 attaactata tcatgaagaa agtacttttg atattggcat gcggcatagc tacccagcta
      781 agctatgcac aagcaacccc aaagtgggcc gacaaagcta aaaaagccgt tttttccatc
      841 gttacatacg ataaagataa caaaatcaag aatacaggaa atggattcta tatcaatgaa
      901 aatggaacgg cattatctga ttacaccctg tttgaaggag ccgaacgcgc agtaatcatt
      961 aacgcggaca gtaaagaatt acctgtattg cgtatcttgg gagccaactc catgtatgac
     1021 atcgtaaaat ttaatactga agccgataaa aagaccatag cattaaaatc ggcatcacag
     1081 ccggcatcag taggtgaaac agtctatctg ctaccctact cgactcaaaa agcggcaacc
     1141 tgccagacag ggaccgtcac caaagtagac accattggcg acaaggcata ttattataca
     1201 ctggcaatga caaccaacga aaaaaccgta agttgcccta ttatgaatgc caatggagaa
     1261 gtattaggtt taatccaaaa aaacgcatcg gatgaggcca aggaaagtta tgccatcgga
     1321 gctacatacg gtgcctcact gagcatcacc gccctttctt tgaacgacat gtcactgaat
     1381 aaaatcggca tcaaaaaagg actgcccgaa acagaagacc aagcactggt gtacctgttc
     1441 atggcatctt cacaacaaaa tcagaacgaa tatatcacca cattaaacga ttttctggaa
     1501 caatatccca acagcgcaga cggatatata cgccgtgcca ctacttatat gggatttagt
     1561 gatgatgaac acaacgcttt ggcagatgct gacctgaaga aagcactgga agtgactacc
     1621 aacaagagtg agacgcaata taatatcgct aaattaattt attcgtacat catctcttta
     1681 ggtgacaaga aaccatacgg tgactggagt tacgacaaag ctctctccat cattcatgat
     1741 gccatgcaag ccgacaacca acccatttac acacaattgg agggagatat tctgtttgct
     1801 atgaagaaat atcctgaggc atacgccgct tatgagaaag tgaaccagtc ttccatagcc
     1861 tctgccgcta cattttactc ggcagccaaa accaaacaac tgattgaagg aacagatatg
     1921 aacgaggtta ttgccttgat ggatagtgct gtggcacgtt tcaccaagcc ttatacatcg
     1981 gaagctgctc cttatttcta tgaacgggca gaaataaaag cccagacagg taaataccgt
     2041 gaagcggtaa tagattatga tactttttat gatgctatcg gtggacgggt tacagccgcc
     2101 ttttatctgc aacgcgaaca ggcggaaata caatgtaaga tgtatcagca agctatcaat
     2161 gacattaata aagcagtaga aatgactcct gaggatgtag ccatgtgggt ggaaaaaggt
     2221 tcggtgcatc tacgtgtagg gcaacataac gaagcaatag aagcattgga aaaggctatc
     2281 tctttagacc cgaaagccgc agccgcatac cgcatgctgg gatactgcca gatacaatta
     2341 aagaaaaaca aagaagcctg tgcaaacttt gccaaagcaa aagaactggg cgatgaagtg
     2401 gtagacggac tgatacagaa gtattgcaaa taataccgga aagctccatc caaaatccgc
     2461 gaatcttgct acgtgatttc tgaaatcttg ttgcatgatt cgcggatttt tgctacaaga
     2521 tttcagggag cattccctgc cattcatgaa aaagcaggaa aggaaaaaat tctacttatc
     2581 ccacaactgc tgtataatca gtacccgttt cgtatcttcc gtcacccgga aacggtcatc
     2641 gctacgctct cctaccagcc atacaatctg gcctgcagag caaaccacat attgattttc
     2701 tttctggaaa agagaaaact tacgatctgt cagataatcg ctgatcttct ttttcccttt
     2761 cattccgaaa ggaacaaatt tatccccctg ccgccattta cgcaccgtga gaggtagcac
     2821 caccttgtct gcatccaaac aggccgtatc cttattctta gggatgacaa agtctggcat
     2881 tatttcctgc gtttccattg caagccggaa cgggggcaca ttttcctcca cttcctcatc
     2941 cgccagcttc ctcctgcgaa taatcaactc cgtcctgtcg cgcagtacct cccatccggc
     3001 agaaacaaac ctttttcccg actgggcaga caaactgcgg aatacatctc ctgcctggac
     3061 agaattgaaa cctaacggat gaagaatctc aaacagcaaa gccgccggag cactctcttc
     3121 catcaaacga gaaataagaa tatgaccgga cttttccatc accctttctt ttcccgcctc
     3181 tatctcctta ttatatataa gagaaacatc agtcagacgc cttgatgttt cagctatact
     3241 ttcactgaca gaaggattca gctcacgcaa catcggaaga atattcagac ggattttatt
     3301 acgcatatat tcatcttgca aattggtact gtctgtaaca taaccttgac gcaaacaacg
     3361 caaataatcc aaaatatcct gacggctcac ctccaacaaa ggccgtacaa tgcagccgtt
     3421 atgcggacta atacctttca agccattgat tcccgcgcca cgtatcaaat tcaataaaaa
     3481 agtttccaca ctatcgtccc ggtgatgggc tacggcaata acagcccccc ccctctcctt
     3541 acgcagttgt tcgaaccaat catagcgcat ttcgcgagcc gccatctcaa tagaaacatg
     3601 atgcctcgaa gcataagtga ccgtatcaaa atgagtaaca tgcaaagcca ctcctaatcc
     3661 tttacacaac tcattgacaa acctttcatc tctatcggat tcctcaccac gaaggtgaaa
     3721 attacaatgg gcagcctcac aatgataccc taaaacaagc aagacacgca acaaagctac
     3781 cgaatctgcc ccgccactca atgccactaa caccttatca tgcaaggtga aaagttgttt
     3841 ctcctctata tacttctgaa tattccaatg aaacatggca caaagataag agttctgcaa
     3901 gacaaaaaca aagtgcccgt tctttattta aaaacaatct aaataatttg catacttcta
     3961 agtaataact tatctttgca aaaaatttaa aacaaaatgc gtttatccga attaagaaca
     4021 ggagaaaaag gcgtaatagt caaggtttta ggccacggtg gtttccgcaa gcgaatcgtt
     4081 gaaatgggtt ttattaaagg aaaaaccgta gaggtaatct tgaacgcccc tttgaaagac
     4141 cctataaaat acagactact aggttacgag atctccctcc gaagacaaga ggcagatatg
     4201 attgaggtgg taagcgagca ggaagcacgc acgatgcaaa acccttacca tggttccata
     4261 acagaagatg tacccgtgcc cgaatcagaa ctggtggcac tggcaaaagg caaacgccgt
     4321 acaatcaatg tagccttagt aggtaatccc aattgtggaa agacttcgct attcaatatt
     4381 gcatccggcg cccacgaaca tgtaggaaac tacagtggtg tgacagtaga tgccaaggaa
     4441 ggttttttcg acttccaagg ttatcatttc cgtattgtag atttacccgg aacctattct
     4501 ctttcagcct atactccgga agaactttat gtacgcaaac atatcattga agaaactccg
     4561 gatgtaatta tcaatgtggt agactcttct aacttggaac gtaatttcta tcttaccacc
     4621 caattgattg atatgaatgt gcgtatggtt atcgccttga atatgtacga tgagctggaa
     4681 gccagcggaa ataaattgga ttatacccaa ttaagccagc tgatcggggt gcctatggta
     4741 cctactgtct gccgacgggg agaaggtgta gacaaactgt tccatgttat catcggtatt
     4801 tacgaaggag gagatttcct gtcacaaaag ggcgaaatac gttctgaaat tctggaagac
     4861 ctgagagact ggcacaaaac ctacgtaccc gaccacgaat tcggaagcca caaagaagag
     4921 gaagatgccc gcccacgcgg atatatgcgt catattcata ttaaccacgg tcctgaactg
     4981 gagcgcagta tcgaagaagt caagaaagca atcagtcaaa acgaagacat acgccataaa
     5041 tattccaccc gcttcctatc catcaaatta ctggaaaacg atagggaaat agaaaatttc
     5101 atctctacac tgcctaatgg caaagaaatc atagcgatac gcaacaagga aacattacgt
     5161 atccgtaaag tgatgaacga agacagcgag caagctatta cggatgctaa atatggtttt
     5221 atcaccggag ctttgaaaga aacattcacc gacaatcatt tggaaaaaga acaaacgacc
     5281 cgcgtgatag acagtattgt gacacatcgc atttggggat atcctatttt tttcctgttt
     5341 ctttatatca tgtttgaggg aacctttgtt ttgggtgact atcctatgca aggtattgaa
     5401 tggctagtag accaattagg caacctgata cgaaacaata tggctgaagg tcctttgaaa
     5461 gacttactga tagatggtat tatcggtgga gtgggcggtg ttatcgtttt cctgccgaat
     5521 atcctcatat tatacttttt tatttctata ttggaagatt cggggtatat ggcacgcgcc
     5581 gcatttatca tggataaaat aatgcaccgg atgggactgc atggcaagtc ctttatccca
     5641 ctgattatgg gattcggttg taatgtacct gccataatgg caacacgtac tatagaagat
     5701 cgaaagtcca gactaatcac catgttggtg aatcctttaa tgtcctgtag tgcgcgtctt
     5761 cccatatatt tagttatgat aggtgctttt ttccctaact gcgccagctt tatgttactt
     5821 tgtatctata cagcaggtat tttattagca gtaataatgg cccgtatttt cagtaaattt
     5881 ctagtgaaag gagaagattc tccatttgtg atggaactcc ccccctatcg tatgcctact
     5941 tctaaaagta tcatgcgtca tacatgggaa aaaggagcac aatatctgaa aaagatggga
     6001 ggcattatca tgattgcctc aattattatt tggtttctag ggtattatcc acggcatgat
     6061 gctcatgaaa gcgtagccga acaacaagaa aattcatata tcggacaaat aggcaaagca
     6121 atagagcctg ttatcaaacc gctaggattt gactggaagt taggaatcgg acttatttca
     6181 ggtgtaggcg ctaaagaatt ggtagtaagt acactaggag tattatacac aaatgaagga
     6241 gatgtggaaa atgtgaatct ttctgaccgt attcccatta ctccactggt tgcattagct
     6301 tacatgttgt ttgtattgat ctacttcccc tgtattgcca ctttcgcagc aatcaagcaa
     6361 gaatccggca gttggaaatg ggccatattc gcagcaggat acaccactgg attggcttgg
     6421 cttgttgcat ttaccgtatt ccaaatagga agtattatca tttaataaac ctaaacctaa
     6481 aattatttgt ttatcaagca tggaattaca acaaattata gttattgcaa tcgtatgcct
     6541 ctgtacaata tggataagta tacgtatctt tcagtatttc aagcgcataa agaacaatag
     6601 caatccgtgt gaatgctgta attctgattg cgccatgaag tctatgcaca acaagccaaa
     6661 gtgcggttgc gaaaaaaatg cagaaaagtg agaaaaaaat agcaaaatat ttgcagatta
     6721 aaaaaaatgt cgtacctttg caaccgcaat cgagaaacaa agattgataa caataaggtt
     6781 ccttggatga gtggcttagt cagcggtctg caaaaccgtg tacggcggtt cgaatccgcc
     6841 aggaacctcc tcatcacttc aaaaataaat atgcaaaagg gaataatcca tagattattc
     6901 ccttttgcat ataatatata aaaagcaacg ccttcaatta ctcaaaagta ttcctattta
     6961 cacctacatt caaaaggttt ctcggctcag tttgaaaaag aacctggaat tatttctcta
     7021 ttccgaagat taaggagcga gtctttctat tttccaaaca ccatcagatt gaagcatata
     7081 gagaaaacga tcatgcaaac gatttaccct accctgccag aattcaacac gaacaggcat
     7141 aacagcaaag cctccccagt attcagggcg atctatctct ttccctatcc agcgcgtggt
     7201 ttctttcaca aaatcacgaa taagttgtat cctgctttct atcggttcgc tttgaggaga
     7261 aatacgggcg ccaatacgac tcttgtaagg cctttttcta aaatattcat ctgattcctg
     7321 tggagatact ttagccgcaa taccttctat atgaatttgc ctttccagtt catgccatac
     7381 aaacgatata gagatagatg ggttatgagc cagatgttta cccttgcgac ttccatagtt
     7441 agtataaaaa ataaatttgc catcatgcaa atctttcaac aacacagtcc gtattgccgg
     7501 tttcccttcc ggagaaacag tacctaccaa catagccgta ggctcattta cctccgcatc
     7561 tatcgcttct tgcagccact ttgtaaaaag gacaagtgga ttatcaggaa gatcactcct
     7621 tttgagacca ccctttgtat attccctcct gattgtcgcc aaatcagcct tcattatttt
     7681 ttctttaact cttaacctat attctttcat taacacttaa atattcttta ctcaataaat
     7741 tccccaaaag accatatcaa aatggacacc atacctcaca taagtatgaa aacaatcttc
     7801 taaaagaaaa ggtttagcaa tttctcaccg ctatgcataa ttgaagaagg acttattttc
     7861 atttttttga aatacaaaat ctttttgcaa accatacatt ttcaatcatt ccactacaca
     7921 catttttctg taatacaaga agatatattt ttgatagatt taattttcat agacaatact
     7981 agctacaaca gaagacaaat tatccttttt tattgcaaaa tcaccataca ataagaacta
     8041 aagcctacac ttgtttgtta aatagaaaaa taagaatagc aaaacgactt gctaccaatg
     8101 cacaaactat ttaattaaat aatgattgac tgtttatgaa aatcttatta ataggagagt
     8161 atagcaatat acattggact ttagcaaaag ccttaagaaa tatgggacat agagtcgatg
     8221 tattatccca cagcaattta tggctaaaca actctgacta tctctatccc aaccggtcat
     8281 caatccgttg gggagttctt aaaaacacgt tcaatttact gaaaaccctt ccccaactca
     8341 gaggatatga tgtggtacaa cttgtcaacc cttacttttt agaattaaaa cccgaactgc
     8401 ttcagtacgt attccaatat cttaaaaaga acaacaagaa gatattttta ggagggtttg
     8461 aatatgattt ttactggatt tacatgtgct taaataaaaa cgctctccga tataatgatt
     8521 tttatgccaa tggcactttt cgtgacacca ttgacaacaa aatggcaatt ataaattgga
     8581 tgcatggatt cagaggaaaa ttaaaccgta tcatcgcgaa caattgtaat ggaatcatca
     8641 ccagtcttta cgaatcctat ttagcctacc aaccctattt ctctggaaaa accaaataca
     8701 ttcctttccc gatagaatca ttgcctcacc cacaaatccc ttttaaaaaa atagaaaaag
     8761 taaaattcta tatcagtcta aaacatcatc gtgaagaatg gaagggaaaa gacgaacttt
     8821 atagcgccct ctataaatta tattacagac atccatctgc atgcgaaatc aaacaaaccg
     8881 ttttcactcc gtatgatgaa tgtgaacatt ttatggacgg gtgcgatgta atgttagatc
     8941 agctttattc ttattctccg ggattaaatg cattatacgc catgagcaaa ggaattgtag
     9001 tggtgggagg tgcagaagag gaacattaca acttattagg cgaagacaga cttcgcccta
     9061 tcatcaacgt acgccccgaa ggaaatgaca tttataacaa actagagagt ttattagcca
     9121 atacaaataa aatttctcaa ttatctgccg acagcattga atatattaaa aaacaccatt
     9181 gtccaataaa ggtggctaaa gaatgtttgg atttttggga gaaaaattaa ttccacctat
     9241 taacacttca ctatcagcac cttattattt ccatcaaaaa atatatctaa aaaaaaagag
     9301 caaaaggttt gcatatttca atttatcccc ttatctttgc accgcgtttg agagataacg
     9361 cttctgataa gaaggaagtt tgggtgagtg gctgaaacca ccagtttgct aaactgacgt
     9421 acgggtaacc gtaccggggg ttcgaatccc ccagcttccg cgaataagtc gtaaattaat
     9481 tttacgactt attttttata ttcatttttc aacagtttgc tgtcaaggct ttcgggagga
     9541 agagtaaagg tgctttttag actttcaatt ttactacata aaacatatga tacttcttca
     9601 tagaaattaa attccgattt ataatagtaa tagcataaaa aaaatcattt tttattttgc
     9661 agattaaaaa caaacttcta actttgcacc gtcttagaaa aagaattaag actaactgat
     9721 ggcggtatcg tctagtggcc taggacgcag ccctctcacg gctgaaactc gggttcgatt
     9781 cccggttccg ctacttttag aagctaattg gtttattgtc accaattagc tttatttttt
     9841 atggaattgt tataaagagt ccttattgtt ttttcattta ttgaccactt tatacttaaa
     9901 aatgcacaag tattcgcatt atacctacta atagtgatgc atagctcaca aaaaaggagt
     9961 acctttgcag ccctaaatct cttaataatg gaataacagt atggaaatga acaaagtttt
    10021 taaggatgga ttgtggagta aggaaattaa tgtttcagac ttcgtacata ccaacattac
    10081 cccttatgag ggcgatgcct catttctggc aggccccaca gagcgaacta aaaaagtgtg
    10141 gaacgaatgc ctcaaggcac tagaagaaga acgtgccaat aacggagttc gttcccttga
    10201 taatgtaaca gtatctacca tcacctcaca taaagcagga tacattgacc gtgaaaacga
    10261 actgattgta ggtcttcaaa cggatgaact tttgcgccgt gccatcaaac cttatggtgg
    10321 tatcaaagtc gtagaaaaag cctgccatga aaacggtgtg gaagtagatg aaaaagtaaa
    10381 ggatatcttt actcattatc gcaaaaccca taatgatggc gtatttgatg cttacaccga
    10441 agaaatccgc tctttccgtt cactcggttt cctgaccggt ctgcccgata attatgcacg
    10501 cgggcgtatc atcggtgact accgccgttt ggcactgtat ggtatcgacc gactgattga
    10561 agcaaaacaa gaagatttgc acaatatcac cagtccgatg accgatgccc gtatccgcct
    10621 gcgcgaagaa gtagccgaac aaatcaaagc actgaaagaa ataaagatat tgggtgaata
    10681 ttacggactc gacttgggtc gtcccgctac taatgcacaa gaagctgttc agtgggttta
    10741 tatggcatat cttgctgccg tgaaagaaca agatggagca gctatgtcat tgggcaacgt
    10801 ttcttcattc ctggatatct atattcaata tgatttggat catggtaaaa ttgacgagtc
    10861 atttgcgcag gaactggtag accagttcat tatcaagttg cgtatggtcc gtcatctgcg
    10921 tatgcaatca tacaacgata tctttgcagg tgatcccacc tgggtaaccg agtctatcgg
    10981 cggacgcttc aacgacggac gtaccaaggt tacaaaaact tccttccgtt tcttgcagac
    11041 actatacaat ctgggtccgt cacccgaacc taatatgact gtactgtgga gtccggaatt
    11101 gccggaaggt ttcaaagaat tctgtgcaca agtttctatc gacacttctt ctatacaata
    11161 cgaaaacgac acgctgatgc gcgaagtgcg taactgtgat gattatggta tcgcctgctg
    11221 cgtttcttat caggctatcg gcaaacaaat ccagttcttc ggagcacgtt gcaatctggc
    11281 taaagcccta ttgctggcta tcaatggcgg acgttgtgag aatacaggaa ctgtaatggt
    11341 gaaagatatt cctgtattga caggggactt gctgaacttt gaagaagtat ggtctaatta
    11401 taagaaagta ttaatgcaaa ttgcacgtgt gtataatgat gcgatgaata tcattcacta
    11461 tatgcacgat aaatattatt atgaaaaggc tcaaatggca ttcattgata ccgatccacg
    11521 tatcaatctg gcatatggcg tagccggtct gtccattgcc attgactcat tgtctgccat
    11581 caaatacggc aaagtacgtg ccaaacgtaa tgatataggt ttgaccgaag gctttgatat
    11641 tgaaaatgca tatccttgct tcggtaatga tgatgaccgc gtagaccact taggggtaga
    11701 tttggtttat ttcttcagtg aagaattaaa gaaacatccg gtatacaaaa atgcccgccc
    11761 taccctgtca ctgctgacta tcacctccaa tgtaatgtac ggcaagaaaa caggtgccac
    11821 tcctgatggt cgtgccaaag gagtggcttt cgctccgggt gccaacccga tgcacggacg
    11881 tgacaagaac ggtgccatcg cctcattgag ttctgtagcc aaactacgct atcgtgatgc
    11941 ccaggacggc atcagtaaca cgttctctat cgtaccaaaa tcactagggg tagaccagga
    12001 aacccgtata gagaacctgg taaccatgat ggacggttat ttcaccaaag gagcacatca
    12061 tctgaatgta aatgtgctga accgtgaaat gttggaagat gcaatggaac atcctgaaaa
    12121 atacccgcaa ctaaccatcc gcgtatcagg ttatgccgta aacttcatca aattgagccg
    12181 tgaacatcag ctggaagtaa tcagccgttc tttccacgaa agaatgtaac atcacatata
    12241 cattcatcgt aggggcgggt tttaaacctg cccttaccag tttaaagaca aaccattatg
    12301 atcagagtcc attcttacga gtcaatgggg acgtttgacg gtcccggttt acgcttagtc
    12361 gtatttttac aaggatgcaa tttccgatgc ctctattgtg ccaaccccga cacaattgac
    12421 accaaaggtg aaagtacgga aacaacaata gacgaaattg tgcgtatggc cgtcagccaa
    12481 aaagcttttt tcggtaaaaa aggaggtgtg actttcagcg gcggcgagcc tacattgcaa
    12541 gcaaaagcac tgattccgtt attccagcga ttaaaagaac aaagcatcca catctgtata
    12601 gataccaacg gcagtatatg gaatgaagaa gtaaaggaac tgctacaatg gacagacctc
    12661 gtattattag acatcaagga atttaataat gtgcgccatc ggcaactgac agaacgcagc
    12721 aacgaacaaa ccatacgtac cgccggatgg cttgaaaaaa acggaaagcc tttttggttg
    12781 cgctatgtat tagttccagg ctatagttcc tttgaggaag atatacgggc attaggagag
    12841 cacttcaaga attatcaaat gattcaaaga gtagaaatac taccttatca tacattaggc
    12901 gtacacaaat atgaagccat gggaaaagaa tacaaactaa acggaataaa agaaaatact
    12961 ctaaaacaat tggaaacagc caaaacgtta tttggtgaat atttcaatac cgtatattta
    13021 aattaaaaat atactgaaga caagatgttg ctataaatca atggaaatat ttcatcattt
    13081 caataaaatt atctaatttc gcatctaaaa cataaattat tataaatatg aaaagactac
    13141 tattactctg cctaacttac attatgtgtg taggcaacca tcagatggct gctcaagact
    13201 cttctgaaag tcctggtatt tttaattcat tagctgtagg cgtcagtgca agtaccacag
    13261 gtataggtat tgatgtagcc agtcctatag gaagttactt ggctgtacgt gcaggagttt
    13321 cttttatgcc gaactttact tattctacag atgtggatgt agatattgaa ggttcttatg
    13381 aaggaaatat acctaccagc atagatgtag aaggaggaat gggacgtact gccggtgaaa
    13441 tattgctgaa tgtatatcct ttcaaatcat ctagtttttt tgtatgcggt ggtgcttatt
    13501 tcggaggagg aaaactcatc aagattaaag ggcacagcga tgagttggca gaactgatta
    13561 aagaaggaca agaagtaggt attgaaatcg gaaactatcg tatacctgta gatcagaacg
    13621 gaaatatatc tggtggtttg aaggtttctt cattccgtcc ttatcttgga ctaggtttcg
    13681 gaagagcgat tcctaagaaa cgaattggct tcatgttcga aatgggtgtg caattccata
    13741 acactcccaa agtatatacc aataacggag atttgtctga tttaacagca gaagctgata
    13801 atgatttcac tgatatcata gacaaactta ctgtctatcc ggtacttaag ttccgtttgt
    13861 gtggcaaaat attctaataa tattctataa aataaaagga gatgagccct ataattttcg
    13921 cctcatctcc tttttatata taagaaacaa tacacttata tcagcaccac catcacatca
    13981 cgtgccccat gagcacccat taccaaagcc tgctcaatat cagccgtctt tgacggaccg
    14041 gaaataaagg ttccgaagcc atattcgcct gtatcaatca gtttatatgc ttcatgcata
    14101 ttgttcacaa tcttattctt gtttagaaga ataaccaatt tttcggcaat aaaataaatg
    14161 gcacgctgct ttacatcctg ttctatccat accgcaccat tctccgcaac cccaatcttt
    14221 ccatctataa cggccaaatc cgtcccattc agttctgcag ggtcttccac atcatcggga
    14281 ttaaatgtcg cacatgtaat agtcttcaga ttagaagcga tgcgtttggc tccaggataa
    14341 gcctttttaa tgaaatcatt cacgtcctcc tctttctcca aaagaatggc ttcccctcct
    14401 acctgcttca tgatgagata aaactgttcc accttactgg gataagttaa tgccatatct
    14461 tccaatggct ttaaatccgg tttctcatat tttacatgtg tagcacgccg gatgctctgc
    14521 aatatatctt ctctgctgct cataattact tcactttacc tttcttccac atttcattga
    14581 aactctcctt agcaaatttc ggcatctcac gcccttttcc ccagtcattc aatccgttat
    14641 agataagaaa acgtggcatt ccgtttacca atggcgccca ttttaatgcc atattgaata
    14701 tcaaagggcg attcatcatg aattccatgc caccggacat tacccttttc atccggtctg
    14761 ccttacccaa tttatccaaa tcctgacgcc acagatagat ctgctccgcc aaatccacct
    14821 tagccggaca cacaaacgaa caggaataac acaaagaaca agccgacaca ttgtcataat
    14881 aatgcaacgg cgccttcaac attcccaggt taatcccgat agggccggga ataaaataag
    14941 tataagagta ccccccacta cgtctatata caggacatgt attcatacag gctccacaac
    15001 ggatacaatt caaagttttg atatgctttt ggtcggccaa tatcttacta cgtccgttat
    15061 ctacaataat aatgtgaagc tccccaccct ctctaggctt tcggtaatga gaagtatatg
    15121 tagtaatggg ttgtcctgta gccgaacggg ccaacaagcg ggtgaacact cctaaagatt
    15181 cacggtccgg cacaattttt tccataccaa aagctgcaat ctgtaattta ggctgggaag
    15241 tacccatatc cgcatttcct tcattggtac ataccacaat ctcaccagta gaagctacag
    15301 caaagttagc acctgtcata gccgcctcag catgaataaa tttctgacgg agattcttcc
    15361 gggctgcatg tgtaaggtaa gtagggtcaa aatttccttt ctccgtaccc atctctcgct
    15421 cgaaaagctc acctacctgt tcacgtttga tatgaatagc gggtaataca atatggcttg
    15481 gcttcagatg catcaattgc aagatacgct ctcccaagtc actttctacc acttcaattc
    15541 ctttgttttc caaaaaaggg ttgagttcgc attcctcggc caacatggat ttgcttttta
    15601 taaaatgctt cactccgtgc tggttcagaa tattgtagac aatattacaa tactcatccg
    15661 cgtcctttgc ccaatagaca tgggctccat tagcacgcgc attgttttca aactccacca
    15721 ataattcatc caaatggctg ttactatata gtttagtagc acatgccata ttacgcaatt
    15781 cctcccattc gggaacttct ttactcagtc tgtcacgctt tgccctaacc agccaaagtg
    15841 tttcgtcatg ccatgcggcc tgtttcttgt ttttcagaaa ctccgcagcc gcttttgaat
    15901 gtttcgtact cataatcctg ccgctaagat ttcaacaatg tgcaatgtct tgataggaag
    15961 tttgtcacgg gcaatgatgc cattctgatg catcaggcac gaactgtcgg cccccacaat
    16021 gtattcagca ccggtagcga tatgacgcat caccttgtca tgccccatct gcacggaaac
    16081 cgcatcttcc tctacggcaa acataccgcc gaaaccgcaa cattcgtctt tacgttccgg
    16141 ttccacaact tccactcctt ctaccaaaga gagcaaatca cgcagtttgc tgaaataagg
    16201 aatattaagt tcgctggcag aagaaagttt catcaatctc actccatgac aactgttttg
    16261 cagactcact ttatgtggaa acttggcttt caacgaagaa ggtctgacga tatcatgaat
    16321 aaactcacag atatcatata tcttaccttc gctggcgcac cgatgtttgt cttctttcaa
    16381 caaacgactg tagttatcac gcacaaaaac gacgcaactg gccgaaggac ctactatata
    16441 atcgtaattc ttaaactgtt cgtcaaaatg gcgggctaaa tctaccgctt tattctcgaa
    16501 acctgcattc gccatcggtt gaccgcaaca agtctggttg agaggataat ccacgtccac
    16561 tcccagactt ttcagcagct tgtacgaggc tatccccacc tgcggatata ccgcattgat
    16621 ataacaagga ataaataaac ctactttcat tgtcattagt taatatgtgt cctatactaa
    16681 ataacaaagt tagaggatat ttgttaagaa aacaacgaga tttctaacga ataatgaagc
    16741 ggaataggta aaaaaacata atattgtggg taaaagcctt actaatgcga atcagtagtt
    16801 gaaataccta cttgattcag ttagttaaaa tgttattat
//
