LOCUS       gnlProkkaDAHCDLOJ_1     5527 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DAHCDLOJ_1.
ACCESSION   gnlProkkaDAHCDLOJ_1
VERSION     gnlProkkaDAHCDLOJ_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:54:41
            Original ID  :: gnl|Prokka|DAHCDLOJ_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5527
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5527
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2:4243]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..4243
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5527
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5527
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..1079)
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 5.9e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_ctg1_1_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.6; E-value:
                     1.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="Aminotran_5 (E-value: 3.7e-32, bitscore:
                     100.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVM"
     aSDomain        complement(201..989)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_Aminotran_5.1"
                     /evalue="5.90E-34"
                     /label="ctg1_1_Aminotran_5.1"
                     /locus_tag="ctg1_1"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             complement(1076..2212)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 72;
                     E-value: 7.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-23, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEVLMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(2224..3525)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.6e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.3e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(3545..4243)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.7e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(4257..5525)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEILWGFD
                     VKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLPVPLKV
                     CSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMDNLHVS
                     EYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQFFWGI
                     CMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLIVFVRN
                     NRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYLIERLI
                     ASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFVSVLSI
                     FAIYCYFKQQLNSLILIPSEIHD"
ORIGIN
        1 ctcatcacct caaagaacct ctcaatatcc tccacatcaa tctctcccaa cgcacaaagc
       61 cggaatgtat tcgttgtgga aatcttaccc gggtagatcg taaagccacg ttcatagcag
      121 taatcatgaa ccttatcaaa atcccagagg ggatcatcag gatacaatac agaaacaaca
      181 agacccgact gccattcacg tttgatcgca tactgaagac caagctcttg caaaccttta
      241 tggatggctt caaagaccct cttgtgacgg gcgaatttag cctcttcacc tactgcaaaa
      301 tattcatcaa gagcctgacg ggcagcgtaa acggtttgaa caggaggagt aaaatgcatc
      361 tcacccgtct tctcaaagta atcgtattgc aaatagaggt tacaatagta ggaacgtttt
      421 ggataatccc ttgaagcacg tatcagggat tcatcaccta tgataaagga aagacccgtc
      481 atggcctgaa gacctttttg agccgaagcc atacaaaagt caacattatc cttcccgata
      541 tcaaaaggaa tcatacccag ggaggaagtg gtgtcgacaa caaaaacggc accgtgcgaa
      601 tgggctattt ttccgatctc acggatgggg ttcaagatac ccgtacccgt ttcatggtgc
      661 gtggtataga ccaaagcgat gtccggattg tcggaaagcg tcttttcgat taccgacagg
      721 tcgggaagtt cgtaaacgga aaacttcaaa tcgatatggg gaagaccgta atattcgcag
      781 acttccaccg cacgggtgct gtaggcaccg ttattgacaa ccagaacttt cttatccgca
      841 ggaagaagag agttcaggca gatatcgata ttgatcgtac ccgagccgca aaacaggacg
      901 gccgtatgtt tggagaggtc tccatgcgca acgcggacca ggtcgtcacg taactgtttc
      961 atcatacccg caaactcttt ctcacgcgga cagatatcgg gaacaacctg cgccagcttc
     1021 accgtatccg tcgtggtggc gggacccgga ttcaaaagga tctttctttc gatattcatg
     1081 aatgcgtatc ttttaaaaat gccataaaat gctctttatt ctctaccgga gtagtcgtag
     1141 ggcgacccag atcatcacgt gaatcgatcc ggaccttaat ttcaagaaga accgggccgg
     1201 acaggccgga cagcttctca agcgcacacg aaagcccttc cttgtcggag gcagtcagta
     1261 catgcgcata accgcaacct ttcgctatcg aggcgatatc cagacggaaa ccgagcgtgg
     1321 gttgaccgcc gacagattca tgggcaccgt tgttgaaaag gacgtgcctg taattcttgg
     1381 gagaaagatc gccgatattg ctgacagcac ccatgtgcat gataaaggca ccgtcaccgt
     1441 caagacagta gacacggcgg tcaggcttct caagggcaat ccccagggca atggaagaac
     1501 tgtgacccat ggaacccaca gttaggaaat cccttgcgtg cccctgccct ttcgattcac
     1561 ggtactcgaa aagctcacgg gagagcttgc ccgtggtgga aaccacaatg tcattgtccc
     1621 cgaggtggtc gacaacctgc attagcacct cctcgcggga cagaggatag tcattcaagg
     1681 cttcctgacg caatttatat tttccaaacg tatctttacg gatgacaatc gcatggggaa
     1741 tcgaccggct cttcgccgag acaaccgcgt catggatctg cgccagggcc tcgtcttcat
     1801 ccgtatccag aattataaaa ggaattttca tggctttcag aagatcaagg gtaacctcgc
     1861 cctgcttctt atgctggggt tcgtctttcg tgccgggctc accgcgccaa ccgaccagca
     1921 aaagaagagg aaggctgtac actttctcgt ccgcaaggga caagagggga ttcaccgtat
     1981 ttcccagacc ggagttctgc atataaacca aaggaacgtt gccagaagcc atataataac
     2041 cgcaggcaat gcccaccgcg gaaccttcat tggcggcgat gatatgctta ccacgcggag
     2101 catgatccgt gatataggcg caaatattct tcaaaaggga atcgggaaca cccgtaaaga
     2161 agtcaacacc gtgatgaagg aacgtatcgt atatcttttc tacacttacc ataaccgtct
     2221 gatttattta gtgcccggaa tcaattccag aatttccttg ataggcatac aaagcggacg
     2281 gacctcctcg gcgcgctcgt tttcaaggat ggtcctggcc acgttcatca tggccgggta
     2341 agcggcacgg agaaggtggt tggcgtaaat gactacgttg gcaccccatt cgtgaagttc
     2401 ggattcgtgc acatggtcat aagtcgtcgg aacaacgaca atgggaacat gggcgtattc
     2461 tttgcggaaa gtccggcaga actcacggat atcctcaccc gacttatcct tgctgtggat
     2521 catgatgccg tccgcacccg cctgtacata ggcataagca cgttcgaggg cgtcactcat
     2581 gggtttgccg gcaataaggc tttcgatacg cgcaatgatc ataaagtcac cggtgacctg
     2641 ggcattcttc cctgctctga tcttatcgca gaaaccctcg atactatcct gagtctggat
     2701 agcgtcagta ccaaaaagag aattcttctt cagaccgact ttatcttcaa tgattaccgc
     2761 agaaatgccg tgacgttcca gagtgcgcac agtaaagaca aagtgttcga tcttgccacc
     2821 cgtgtctcca tcaaaaataa taggcttggt ggtacattca aggatattgt tcaggtcctg
     2881 taaacgggtg gtaaggtcga ccgcttcaat atccggttta cccttactcg tagagtcggt
     2941 caggctgctg gaccacatgc cgtcaaagac ctcgcgctta tcacccttct ggacttcaag
     3001 attctcaata atcagaccgc aaagaccgtc gtgagcctcc aggatacgga ccacaggctt
     3061 ggcctggatc aggcggcgga gggacttaag acgtacgtca ggggtagtcc cgatcgcctt
     3121 gatatccttg tcgagcgagg aggagttgat gccccgggta taagggatct cgattacctt
     3181 gcccccctgg gcgttcatca cctcaaaaac ctgttcgcgc acctcgcgca acgggcccgt
     3241 tttccagtcg tcgccgtgga tgatatagtc aggcttgagt ttttccagat tcggaacata
     3301 gctccaatcc tcctggggaa caacttcgca aacccctttg atattctcaa caacctcctt
     3361 acgctgatca taggtaaggt aagggaggcg tttgtgttcg gcgatggcct tgtccgtcag
     3421 cagaccgacg atgacatcac cgtatttagt agcttcatga ataatatgga tcaaccccgg
     3481 atgcatgata tccgcggtca taccgacata gattttcttg ttcatatatg gaaaagattt
     3541 gtttttaaca atagcggatg atgtgctcct cagcatacga aaggtcggct tcatcatcga
     3601 tttcatacca tttaagaccc tccaccctga gcacacggac aggggaaacg gaacgggaca
     3661 tgcggagcag ttcgtactcg taacccagtt taggctggga ctccaggatg gtcgcataat
     3721 cggcgcacat ccggcggtag aaagtattgg aaagtttatg gataccgacc agctcgcctt
     3781 ttgcctcaag ggcgtccttg tctaccgaac aggaagtaag gatgtgattg cggtcatatt
     3841 ccacataata ctgatcctgg aacttggtca gagaagagac aagcatcaca tccgggaatt
     3901 cgtcatccag cagcgagagg atggccttgc gttcaaaaac aaggtccgat tcaagcagca
     3961 ggaaactgtc atcgcctatc acgtcacgcg tattgtacag agtgtacata ctgttagtat
     4021 cggcataacg gggactgaaa caggtctcta tctgggggaa atccgcctga agggcttcat
     4081 aagcctcttt tttataaccc gtaccgagga tgatacgttc gataccgcag gaaagaaggg
     4141 tttcgataga gcggataatc ataggttttc caccaacctc cacaaaacct ttgggcacaa
     4201 gctcggtata atgcccgaag cgggtaccaa gaccggcagc catgatcatt gctgttttaa
     4261 tcatgaattt cagagggaat taatataagt gaattcaatt gttgcttgaa ataacagtaa
     4321 atcgcaaaaa tcgacaggac agaaacaaat cctgaaaaaa gggcagtacg catcagcatg
     4381 acagtccagg aaatgtcagc agaaacgaag ttcttgacca taaacacacc cgtagtgccc
     4441 agatagccga aagaatcggc caaataaata ataaaaacag ccgtactaac caccctaagg
     4501 gaagcaatca gacgttctat caggtaagtg aaaggaatat accccatata cagaccaaga
     4561 ccggaaagaa tcatccacca aataggagaa agaaaaccgt acacataaag caatgtggaa
     4621 aaaaccatta aggaaccgcc tgtgacggcg atgcaataaa tgatattaag agccaaacgg
     4681 ttattacgga caaacacaat caggaacatc agtacaagga caaaaacggc aatgggaacc
     4741 tctgtctgag taaagatcat tgcaccctca atatggagct ccttccaaat atcggcagcg
     4801 aaagagtcac gaagctcacg gaacacggtc agggcaccgt aaaaaacaac cagcatgcag
     4861 attccccaaa agaattgcct caaaaactta cgcctgtctt taccatccat cggagcacgt
     4921 ttggtacgct gtatgatatc ttgctcattg ggagccggaa tctgattgag aagccagctg
     4981 caaagcaaca taacagggta taccaacaaa ccggtggtaa aaggcatcca atattccgac
     5041 acatgcaaat tatccatcac gaattgtccc aaggttttca ccaaaccgga agagactatc
     5101 aaagcaacgc tcagcccgac attcaatatt tcactgatac gacgtccttc gatatagcta
     5161 aaaatgacac cccagatcat acccagggga agaccgctca gaaaaataga acacaccttc
     5221 aaaggaaccg gaagaagtgc aaaacccaac aaagcaactt cggaaaaagt aagcagccct
     5281 attatataat agatgcggtg acccgctttc atcgaaggca gaatacgaac accgatgaac
     5341 ttggaaaggg cgtagccgat aatctcagaa aggacataca ggattttgac atcgaatccc
     5401 caaagaatct caccttcata aatggctgcg gtaaatggct tacggtaggc ataggcacaa
     5461 gtataaacca gaaaaatcaa aacgctggca tagagagcca aaacgtaaag gggagaacgg
     5521 gaaagaa
//
