LOCUS       gnlProkkaGIPLNKEG_52   11768 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GIPLNKEG_52.
ACCESSION   gnlProkkaGIPLNKEG_52
VERSION     gnlProkkaGIPLNKEG_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:04:11
            Original ID  :: gnl|Prokka|GIPLNKEG_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11768
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11768
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1420:1768]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1421..1768
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11768
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11768
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             58..1122
                     /locus_tag="ctg52_1"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             1144..1431
                     /locus_tag="ctg52_2"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(1421..1768)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_3"
                     /sec_met_domain="PF05402 (E-value: 2.1e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 7.9e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(1813..3201)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(3492..3887)
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPVAE"
     CDS             complement(3894..4427)
                     /locus_tag="ctg52_6"
                     /transl_table=11
                     /translation="MPLSEVLKDEPTVDRTLALIDAFLSTAPEEVTSQTSFDYSMDYTA
                     YLLEETPVADEPAEAMPKLKGHELIDNFIEKSETDPVVYLKPLREEEKAKAASSAETNE
                     TGRTDETTETNTIEEEDDSCFTETLAKIYVKQQRYSKALEIIKKLSLKYPKKNAYFADQ
                     IRFLEKLIINANSK"
     CDS             complement(4693..5220)
                     /locus_tag="ctg52_7"
                     /transl_table=11
                     /translation="MNWIKKIARPLILVVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(5207..6448)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_8"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(6572..7666)
                     /locus_tag="ctg52_9"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGHGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(7671..8708)
                     /locus_tag="ctg52_10"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFDCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTREA
                     EPTNK"
     CDS             complement(8726..9760)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_11"
                     /sec_met_domain="PF04055 (E-value: 1.7e-17, bitscore: 54.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLIELQSLVKRLGMPGFAAKQIASWLYDKKVTSIDE
                     MTNLSLKYRELLKQNYEVGAEAPVEEMRSVDGTVKYLYPVGENHFVESVYIPDDERATL
                     CISSQVGCKMNCKFCMTGKQGYSANLTAHQIINQIHSLPERDKLTNVVMMGMGEPLDNL
                     EEVLKALDILTGSYGYAWSPKRITVSTVGLRKGLRRFIEESDCHLAISLHSPVTAQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRI
                     NLIRFHSIPGVALEGADMDMMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQEE
                     NNKS"
ORIGIN
        1 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
       61 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
      121 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
      181 cagatagaaa tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa
      241 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
      301 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
      361 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
      421 tcaatcaatg tcccctacag cagtaacaat gcaaagaatg cagcaaacaa tgccgttgct
      481 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
      541 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
      601 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
      661 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
      721 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
      781 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
      841 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
      901 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
      961 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     1021 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     1081 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     1141 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     1201 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     1261 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     1321 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgcttat cattatgggc
     1381 gtactgatag gatgtgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
     1441 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
     1501 cttcatattg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
     1561 ctatcaggtt ccatacggcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
     1621 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
     1681 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggt atcacctcca
     1741 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
     1801 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
     1861 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
     1921 catcggcaag gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
     1981 gttcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
     2041 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
     2101 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
     2161 ccaccatata ttcagaatag gaagagcgaa catcgtgtgt acgaaaatca gcatcaccga
     2221 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tataatgaac cgaacaatgg
     2281 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
     2341 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
     2401 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttggtaa tgatatagac
     2461 aatgtctttc atgcggaaag gttcttccgg ttccagtcct tccgcatcca gtgaagcatc
     2521 cagtttctta tcgtagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
     2581 gagacagaac agaatcggag cgggaatatt ggtatggaat acgccgctct catccgtaga
     2641 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagttgttc caatacgcgc
     2701 ggtcgccatt tccagtccca tagcgagagc catctctttg cctttaaacc acttcacgat
     2761 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccgaaaatag cataacccaa
     2821 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
     2881 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
     2941 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
     3001 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
     3061 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
     3121 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgcggagt cattcagctt
     3181 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
     3241 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
     3301 gacatctgac cggatattcc tgtatgaaga agagcagacc gggcccaata ataaagacag
     3361 acgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
     3421 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
     3481 ctgtcactga attattctgc tacaggagca ggagtttcag tagccggagc ttccgttgct
     3541 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
     3601 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagctgca
     3661 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
     3721 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
     3781 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
     3841 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
     3901 gaattagcgt taataatcaa tttctccaaa aatctgattt ggtctgcaaa gtaagcattt
     3961 ttttttggat atttcaagct taatttttta attatttcaa gagctttcga atatcgttgc
     4021 tgttttacgt agattttggc caaagtttct gtgaaacagc tgtcatcttc ctcttctatg
     4081 gtgttggttt cagttgtttc gtctgttctg cccgtttcgt ttgtttcagc ggaagaagct
     4141 gcctttgctt tctcttcttc cctcaaaggt ttcaggtata cgactggatc agtctcgctt
     4201 ttttcgataa agttgtcaat cagctcgtgt cctttcagct tgggcattgc ctctgccggc
     4261 tcgtcggcga caggtgtctc ttcgagaagg tatgccgtat agtccatgga gtaatcaaag
     4321 cttgtctgac tggttacttc ttcgggagcc gtcgaaagga aagcatcgat cagagccagt
     4381 gtccggtcga cggtaggctc atctttcaat acttcagaga gaggcaaccc tttcttctgg
     4441 gattcgacag cgaagcgttc gccttcgatc agatgaaaca gtttccgtcg gtcggcaata
     4501 tacagaacgg ctttccgcag ttccgcaccg aaattaatgt cgtggagaat atacaggttc
     4561 ttgagataca acaaccggag cgactgaaaa tacggatacc tcgcgagctg gttgcgcagt
     4621 tcgtacaaag tatccctatt cagcgtctcg ggatgctgaa tccattgttg caagttaaca
     4681 gaagtcatta aattaccagt ttgctacagt tgcattaaat atttggtcgg ttatctcttt
     4741 actcatttcc gctattaatc catcctgtac ggccgtcagc agctggctgg aatcataggt
     4801 acggaaagct gagaattgtt gttcgaagtc ttcggcgtga tttgtgttgt tgacaaagcg
     4861 tacattgacc gtgatggtca gcttcgtttc cgaagagtaa ccatcggcag acactgcctg
     4921 gttatactgg ttgtagcccg taatttcacc gtcaatctgc agatccgcat tctggttcgg
     4981 tttcagcagt tgcagacggg tctgtctgat gaagatatct ttcaggtctt cattgaactt
     5041 ggtagccagc ggagcataca catactccga cttaatcggg aaatcagcaa tcgaaatagt
     5101 cttcacctta tcgtaattga tagaggagcc attaaactta taggacacac tacaggcgat
     5161 gatgactgcc ggtaaaacaa ccaatatcag cggtcgtgct attttcttaa tccaattcat
     5221 attcttttat ttttctgtaa agggtacgct cggagatatt cagatccttc gccgcacttt
     5281 tccgcttacc atgatgcctc tcaagcgctt tacgtatcat ttctttttcc acttcatcga
     5341 gcgaaagggt ttcttccaca tactcttccg tgtcctgaat atcgtcatcg tcttctttgg
     5401 gacaaacaga cggttgctgc acagcatgga ttatggccgg cacggaaggt tggtgcgtcg
     5461 ttgtcactac cggagtagct actacctgtc ccatctgtcc gacttgtccc gcacgttcgg
     5521 ccatcatatt gtgcaccatc ttcttcagtt ccgccacttc ctgacgcata tcgaacaaga
     5581 cagaatatag tatttcgcgt tcgctctcaa agctcttgct ctcgcgtgtg ccgaacagtg
     5641 ccggaaggcg ttgggtattc tgtgccggaa gataggtctg cagaatcgca gccgttatct
     5701 cacggtttgt ttctataatc gaaatctgct ctgtgatgtt cttcaactgc cggacgtttc
     5761 ccggccacgg ataagcaagc aatatcttct tggcatcttc cgtcagctgg atagccggca
     5821 tccggtactt ttcggcaaag tctgcggcaa acttacggaa caacaacagc acatcatctc
     5881 cacgctcacg caaaggtggt atctgaatag gcaccgtgtt caaccgataa tacaaatctt
     5941 cccggaagcg tccttcggca atggcttgtg tcaggttcac gttggtcgct gccacaatac
     6001 gtacatccgt cttttgcact ttggatgaac ctaccttgat aaattcaccg ctttcaagta
     6061 cacggagcag acgcgcctgt gtaggcaacg gcaactctcc cacttcatca aggaagatag
     6121 ttccaccgtc agcttctcca aaatatcctt tccgctcacc aatagcaccg gtaaatgctc
     6181 ctttctcgtg tccgaacagt tcggaatcga tcgtaccttc cggtatggca ccacagttga
     6241 cagcaatata ctgcccatgc tttctccggc tatattgatg aatgatctgt ggaaaacttt
     6301 cttttccgac accactttct ccggtaatca gcacagacaa atcggtaggc gctacctgaa
     6361 tggcaacatc tatggcacgt gataaagcct cggtattgcc aataataccg aaacgctgtt
     6421 tcacttgttg tatctccgct ttggtcatct atcttaatat taagtaatag gtaataagta
     6481 ttaagtaata agtattaagt attaccatca ttatcatctc gcttccatcc gcatggctaa
     6541 tacttaatac ttattactta atacctatta cttaatcttc gtctactgta tccagtttta
     6601 gtttatcact atcgtcccgc ttctcgtaat actgcttccg caacgggttt acccgtgccg
     6661 ctttctcgcg ctggcggttg cggaatacat caatcgctac ataaatagcc tggcggaaag
     6721 agtcttcgct ggccagtcct ttaccggcga tgtcataggc tgttccatga gccggagagg
     6781 tacgtacaac cggcagtccg gcggtatagt tcacaccgtc ttccatagcc agggctttga
     6841 acggagccag tccctgatca tgatacatag caaggattcc gtcaaagtga gtataattgc
     6901 ccgaacccat aaaaccgtcc gcagcataag gaccgtaaca gatgatccct ttctcttcca
     6961 tttctttcat ggcagggata atgatttcct gttcttccat acctagcagt ccgccgtctc
     7021 ctgcatgagg attcagtgaa agcactgcaa tacggggcgc accgataccg aaatcctgtt
     7081 tcagacaacg atggaaaatc atcagctttt cctgaatcag ttccttggtg attgttgtag
     7141 caatctccct taccggaata tgcgtcgtta ctaaagccac acgaaaatcg tttttcatca
     7201 agatcatcag tgacttgttt ccatggccca gacgttcttc aatatactcc gtatgcccgg
     7261 ggaaagagaa ctcttccgac tgaatggtat gtttgttgat cggagctgtc acaatgacgt
     7321 cgatcagccc ctcacgatac tcttctatgg cacgctccaa agcacccaat gcagccttac
     7381 ctgcttcggg atcgggtttg gagaattcca ctttcacttc gtcatctgta cagttcacta
     7441 cactcagacg gttgtatccg gcttcggaag ctgtgttgac aatgctgaaa ttagcctgta
     7501 catccagtgc tttacgatgg taagccgcta ctttaggtga accgtagata atcggagtac
     7561 atagctcaag catggtaggg tctgagaatg tcttcaagat cacttcataa cctaccccgt
     7621 tgatatctcc ttgggtaatg ccgattctta ttttgttttc ttccatgttt ttatttatta
     7681 gttggttccg cttctctggt tacccccagt ggaatctgac tctgctgacc ttcttgcgga
     7741 agtttcagcg tataaagaga tgcttccatc tggcgaacca gattgcgttt cattttatcg
     7801 ggtgaatata caaatatttc tgctgtaata atacgttggt tcttctgatc cagacgagta
     7861 tgggaaacga acgggccacc catgaagtca cccttcatgc gccacaatcc acgagcttcc
     7921 atcgtgtagt cattgtgcac gttgatcgga cgaacatcgg tcagtaacga gtctgtcgac
     7981 atatatacgc cttctttata tccggggata ttggctttca tcacagaatc gcgcttatga
     8041 acaaagtatt ctttggtgaa tgtatccttg tcagtataag gataagaata catcacgaaa
     8101 ttgcgatccg cgctgcctgt attggtagat gcccaaaaga agtcctctcc tgtcttggag
     8161 ttattcagtt cggaaggtat ccagatatcg cagtcaaaca gactatctac cttatttgag
     8221 ataaagttgt tgtgcttttc ctccagcaaa gtaatctgac ggttcatttc agcgcgagtg
     8281 aagaagtcga taatcgtctg cttgttttct tcgacaaact tctcaaacac ttcttcgttc
     8341 ggagcctgaa tggtcagtat catctgtgga gaagcataaa cgtctttcgc atacttgaaa
     8401 gtacctttgg tataaatatc ttttatatct actatcacaa tattacggat caacttcagc
     8461 gtagaatcat agtccttcgg tgaagtatac ataatccgga aagaaggttc cgactggggc
     8521 agtcccggca tgtcagaatc aagcacatca tgcaaggccc ttccggcggc acggtcccac
     8581 actcccgcat ctactacaac caacagttca tacggacgac cgctagaggt atgattcccc
     8641 tttaatccac aagaagcaac tacgaaggct accaaagcca tgcttaaata aaaaaagtac
     8701 tttttcatga tgttcgattt ttatattaac ttttattatt ttcctcctgt ttcgcagtcg
     8761 acagcatacc gcatgccgca aaaatatcct ctccccgcga agcacgaatg gtagtgaaaa
     8821 gcccgtgcgt agtcagatag tcacggaaac gggtcatcat atccatatcg gctccttcaa
     8881 gggctactcc cggaatagaa tggaaacgga tcaggttaat ccggcaatcc agtccgcgaa
     8941 gcagtttgag taactccttg gcataaactt gcgaatcatt aagcccctta aaaacaatat
     9001 attcaaacga aagtcgacgc tgtttgctaa aatcatagtt ttttaacagt tccaccattt
     9061 ccgtgataga aaaggctttc tccgccggca tcagttccgc acgctgggcg gtcaccggag
     9121 aatgcaggct gatggcaagg tgacagtcgc tttcttcgat aaagcgccgc aatcctttcc
     9181 gcaatccgac agttgaaacg gtaatccgct tcgggctcca tgcataacca taggaccctg
     9241 tcagtatgtc caatgccttc aacacctctt ccagattatc gagcggttcg cccattccca
     9301 tcatgacgac attcgtcagt ttgtcccgtt ccggcaagga gtgaatctga ttgataatct
     9361 gatgggcagt caggttggca gagtagcctt gtttcccggt catacagaac ttgcagttca
     9421 ttttgcagcc tacctgtgaa gaaatgcata aagtcgcccg ttcatcatcc ggaatataca
     9481 ccgactccac aaaatgattc tcgcccacag ggtacaggta tttcaccgta ccgtctacag
     9541 agcgcatttc ctccaccgga gcttcagctc ctacctcata gttctgcttc agtaactccc
     9601 ggtatttcaa cgacaagtta gtcatttcat caatcgaagt caccttctta tcataaagcc
     9661 aggatgcaat ctgtttggct gcaaagcccg gcattcccag acgtttcacc agtgactgca
     9721 gctctataag cgtcattcct aagaggggat atttagacat cattctttct gttcatggtt
     9781 tatatttgca aatgtaagga aataaagtcg atttccgtat agcaaggatg taaaagttag
     9841 caaaaaaggt cgttccaaag catggaacga ccttttgcag ttatcgtttt tacgactaat
     9901 cttagaagaa caggtaacgt gtatccttca cttttccttt cagatacaga tcgttcatca
     9961 gacggcttgc gaagcgtgcg tgcatattag ccaatgtagc ttcttcatct ttagcgttaa
    10021 aagtatcgct cagtttgtct ttgccataca tctgaagcac aaatacaccg gcattacctt
    10081 tgattggagc actcagtttg ttcatttcag ccacagaagc ataagcacct accagcggtt
    10141 cgctgctgcg caattcagag acataagcgg gagcggcaaa tgtaaccagc ttcaaagaat
    10201 cgctgactgc gccgggcata gccttgtact ggtcgagaga agttgcattg gcagctttca
    10261 tatcagccat gatcttttcg gctttcttat ctttaacgat ttcagctctc aactgatcct
    10321 gtacagcttt cagcggacga tatccttccg gagtaacacc aaccagagct actgcaacca
    10381 tatggtcgct ttcgccacat tcatacaaac cggaaacatc acccggttta gcggcaaatg
    10441 cccatctcaa tgcttcttta gtacctctta caccaccgat agtgtgttct gagctataca
    10501 agtctcttct gtcaagcagt ttgtatccgg cttcttcagc gttagcgatc atcttttcag
    10561 cagtaggatt ggcagcgatg aactggctga agtcattgta agcacggtta taagtttctt
    10621 tactgaattc aacttcacgt ttcacaacag ctactttata tttatccttc acagctttct
    10681 tgttagtcac ctgcaggatt acattagctt gtcccaacgg caggtttact acttcgttca
    10741 cgcctgtatt attgatagca gagataaact tcaggttgtc accatcgatc tgtgcgcctt
    10801 catactgtgc agagctcatc cagttagtct cacccgtctg accgtatttc ttagccagat
    10861 ctgcgaagtt agcaccgcct ttgatagcag tatagatact gtccgccaag gcttttgtct
    10921 tcaaagcgtc ttctgcaaac acctgaatct gacggaactc gattgagtcg gcagcagctg
    10981 tttttgcaac cactttgaat gaattaatag tattgtcggc accattatag tacggaccat
    11041 aaacagaacc aacggatgca gagtccagac gggcaactac atctgacggg aaagctgttt
    11101 tattatagaa caagtctaca taaggagctt ccgaacctac agaacggatg aaagaagtat
    11161 aatcatctgt tgtagtagcc agctgtgcag tagcttcgtc tacttcctgc tggatagcag
    11221 ctctgtcttc cgcacttgca gtcacctgaa catcaatgta cttgatatca cggctttcct
    11281 gatattgctt gaactgttct ttcttcttgt tataaaggtc tttcagttcc gattctttca
    11341 caacgattgt agaatctact acagaagaat aaggaacggc agccatcaac aagtcatatt
    11401 gattcactct tgcgtcgaaa gcgtcctgtg cttctaccgg gttagagaga agcgcttttg
    11461 ctaccaatgc ctgatatttt tctgccaggc ggctctgaac caatgtcttc tggatgaatg
    11521 accagtattt gtacatgttg ttgtactgtt ctgcatactg agccggcatc tgagattcgt
    11581 tcattttagc gtaatctacc agaaacttat tcagcatatc cttatcgaaa gcaccggtct
    11641 gcgggttgcg gaaaggagtc tgttgcaaca acggatgcac gcctgctttc aggatatcct
    11701 gaatttcagc agcagagact gtcagtccca atgcttttgc ttctttctca accagtttgt
    11761 tattaacg
//
