LOCUS       c00041_gnlPro..        14000 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GIPLNKEG_41.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:22:29
            Original ID  :: gnl|Prokka|GIPLNKEG_41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 188761
            Orig. end    :: 202761
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14000
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[198761:202694]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13933
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..14000
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="GR_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14000
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_fatty_acids"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2432..5188)
                     /locus_tag="ctg41_141"
                     /transl_table=11
                     /translation="MRRILLGLCVLFFLNAHGQEIPLPEKMPQDHPRVLTTPEGKKETW
                     KLIKKEAWAQDVFNKLKERTEVYTRRTESQPDWLLSRLAMYWKSHATEVYVKGEVFDHA
                     GGAKAPAPTVRYTGTRGTAATHGRPKLEDVVPYDDSAEGNVTFCNNALEGRPQESVHPS
                     KTGRNIESLNCEILGIARDAAFLYWMTGEEKYARLAAGVFDTYMTGIYYRNVPVDLNHG
                     HQQTLVGLTSFEVIHEDALHIVVPLYDFLYHYLQSNYPDKMMIYAGALKKWADNIITNG
                     VPHNNWDLLQARYIMNVGLVLEDNEEYADGKGREYYIDYVMNRSSIRQWSLTKLADYGF
                     DSETGIWAECPGYSSVVINDYANFTHQFDHNLQYDLVKAMPVLAKAVAATPQYLFPNRM
                     ICGFGDTHPSYLSTNFFIRMIQNAQANGKKEQERYFTALLKCLNPEEGSEKSGKKNVRA
                     SVNSFFEDKPLVLDPKVEAGKIEDYVSPLFYAPNVSWLVQRNGMHPRNSLMISLNASEG
                     NHMHANGISMELYGKGYVLGPDAGIGLFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVM
                     KSNHSFDLLSCFPASAEPGKGFTSVTYSQVAFREPESRADQTRLMGIVTTGPETGYYVD
                     VFRSRKERGGDKMHDYFYHNLGQTMTLTAANGTDLNLQPTEELAFAGAHLYAYSYLYDK
                     KVATTGQDVKVTFTIDMKDKGGDDISMNLWMKGEPEREVFTALSPMTEGLSRTPHMPYN
                     IKEQPTLTFVARQHGEAWNRPFVAVYEPSTQKEPSAIQSVSYFDAEEPGLKDFAGICVE
                     SKNGRTDHIFSLTDSSQTATYQGMKVKADYAVISNEYAGNRTLFIGNGTQLIASGISIQ
                     TSEAANVLLEKKQGKWYILSSAPCKMVIDGKAVQSGITTELTLLAVQ"
     CDS             5770..7677
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_142"
                     /sec_met_domain="Fer4_7 (E-value: 5.3e-10, bitscore: 33.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.9e-10, bitscore: 32.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.7e-50, bitscore:
                     163.4, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 2.6e-11,
                     bitscore: 36.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 5.7e-34, bitscore:
                     109.2, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILSIHDLQIIRKRAEHHLSLREESNEKVSEKCCGLASGTAHLQ
                     ILICGGTGCKASSSQGITENLQKAIERNGITDKVDVITVGCFGFCEKGPIVKIIPDNTF
                     YTQVTPEDAEEIISEHIIGGRRIERLLYIDPKTEQTVSDSKHMDFYRKQLRIALRNCGF
                     IDSENIEEYIAREGYFALADCLLNKQPADVIDVIKRSGLRGRGGGGFPTGLKWEFASKQ
                     VSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEAMCICGYSIGSSKGLVYIRAEYPLA
                     INRLKKAIEQARAYGLLGDHILGTDFSFDIEIRYGAGAFVCGEETALIHSMEGKRGEPT
                     LKPPFPAESGYLGKPTNVNNVETLANIPIILTKGAEWFASIGTERSKGTKVFALAGKIN
                     NVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQTGGPSGGCLTEKHLDTPIDFDNLLA
                     AGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESCGKCTPCRIGNKRLLELLNKITEGR
                     GTEKDLDTLATLGRVIKDTALCGLGQTSPNPVLSTLDNFRDEYLEHVRDKTCRAKQCKS
                     LLTYTINPELCIGCHLCAKNCPADAISGLVRKPHVINPEKCIKCGMCMARCKFKAILVC
                     "
     CDS             7689..9455
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_143"
                     /sec_met_domain="Fer4 (E-value: 1.2e-08, bitscore: 27.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 1.8e-22, bitscore: 72.5,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 2.9e-18,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGT
                     CIKNNPASCRICVVEVAGRRNLAPACATRCTEGMVVKTSTLRVMSARKVVAELILSDHP
                     NDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRRCES
                     VCNDVQTVGALGAIRRGFNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRL
                     LDDLADPDKIVIVQTAPAVRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAAD
                     LTIMEEGSEILNRLTRYLDGDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQ
                     MFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELA
                     RLIKRANIGFTLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVN
                     FEQVRGLSGVRRATIDLNGFELKVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGC
                     IGGGGQPLHHGNSDVLYARANALYREDANKPLRKSHDNPYIQKLYEEYLGKPLGEKSEM
                     LLHTHYFNKSID"
     CDS             9474..9950
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_144"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 9.4e-54,
                     bitscore: 174.4, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVVEQVKTICDKHGNNAGELINILHEAQHLHGYLPEE
                     MQRIIASKLRIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKYSLDCLRCVGACGLAPVVMIGEKVYGRLQPVDVKKIIEELE"
     CDS             complement(10001..11008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: ACP_syn_III_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_145"
                     /sec_met_domain="Thiolase_N (E-value: 6.6e-11, bitscore:
                     35.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 2.5e-32, bitscore:
                     103.9, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 2.5e-34, bitscore:
                     110.6, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKINAVITGVGGYVPDYVLTNDEISKMVDTTDEWIMGRIGIKER
                     HILNEEGLGTSYMARKAAKQLMQRTKSRPDDIDLVIVATTTSDYRFPSTASILCERLGL
                     KNAFAFDMQAVCSGFLYAMETGANFIRSGKYKKIIIVGADKMSSVIDYTDRATCPIFGD
                     GAAAFMLEPTTEEVGIMDSVLRTDGKGLPFLHIKAGGSVCPPSYYSLDHHLHYIYQEGR
                     TVFKYAVANMSDSCEAIIARNHLTKEDIDWVIPHQANQRIITAVAQRLEVPSEKVMVNI
                     ERYGNTSAGTLPLCIWDFEKKLKKGDNLIFTAFGAGFAWGAVYVKWGYDPKEDA"
     CDS             11705..13933
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_146"
                     /sec_met_domain="Gly_radical (E-value: 9.1e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
ORIGIN
        1 gatcacgact ggattcctga cactgaccat taggataaat ataatattga agctgttcgt
       61 cataaccata atcctgaata tcattcttcc gttgtaacaa tttataatca atcatagtag
      121 gagaaacatg aatgggttga tcgctggaaa tagccggtcc tgaaggatat ggcaaatcat
      181 ctttacgatg tttcattccc agtaaatagc gataagcacg gtcatacatt atctcattat
      241 caagatagat agccattgcc atcatactgc gtgctgcaaa caatccttga ttaccgaaac
      301 gcgctgcatc aaaattatag atattccaat aaaaagttac tccatttttt gtatcatcca
      361 gataattagc atatttagca gaataatttt ccgtattact ataccccgga taaaccagca
      421 tatctttgaa acgttgctga tcttgccgtg tccatccaga ataatctctc atcatttcag
      481 ccgcatcaat caacaaataa attttcccat tatccaacgg tcctgtacca cggctactag
      541 tattagtata ataagaattt gcattcaaat attctacagc cttacgtgca taggcttctt
      601 ctcctgtcaa gtgccaaaga agagctaaat catgagcacg acgcccatcc accccgattg
      661 tagcattaaa tcgcccttcc tttatttgct ctccacgatt caccacaggt gcatcaagtg
      721 atgaataaga agactccttc aatttcaaaa aggtagaata ataaggttct tgtctggctt
      781 ctaccattgc tttcatacga tcgaggtcac cttgcgtata agtaataccc ggatgaacaa
      841 aacgacgttg tgactgagct acatcacttg taaaaacaat attttccaca tgaggtccta
      901 catatatgcg tgccatatct gaagtcttat accaccgagg tttgtccggc atattatcat
      961 caatcaattt tccatttatt ttcaaatttt caaaacgtat gttctttacc ttacgttttt
     1021 catcatatcc ttcaataata gaaagttccg cattctctcc ggtataggat atattcttaa
     1081 acaatacgtt ctcaattcct cttccgggag cagtacagta tttttcatta taaaagatac
     1141 gtaaattgac aagttgcccc tgacggaaat tctcaacacg gatgtcctca aaatgaacat
     1201 tgcgtattaa attgttatca cctgcattaa tagccataca tccttgataa tcgacttgtt
     1261 tctctctatg atccaatata tcaatattaa tataattcag atcttccaaa acttcgggag
     1321 ctttagaatt accatgaatt ccaataaaaa taggatgggc tacatctgcc caaagagtgg
     1381 aattctgcat tgttatattc cgacaacctc cttcaaatcc caaacgagtg ccataaacag
     1441 ttgtacaatc atctgagtta cggcagaaga caccatcaaa taatacgtta ttgctcgcaa
     1501 aaacattcat gccatctccc cacccataat aactaatact tttgacatta cggatagtaa
     1561 cattttccga ccctcctgtc gcacattgag tagcaacaat tccttctaca tagacatctc
     1621 gggaattcgc aatacgaata cctcctttta tagaatgatc gataattcct cttcctagca
     1681 attttacatc atgtacgttt tcgattagga cacgccccat taaaacagct cctcctgcca
     1741 gatacacagt cttaccggat ggcactctca attccccatt tttaactgta tgtattccag
     1801 gaccaaagta aattacttcc ggattatctt tgtccggaat cgttctttcc ggagatcctg
     1861 taaataagtg aagattatga aaaatatccc catttacttc tactgacaaa tttcgaggat
     1921 gctctaatgt aaaagttact gtattaccat cgatctgaaa tgggatatca tacgagagag
     1981 gacggacttt tgccgtctgt acttctccca aattataggt tacggctact tccacttttc
     2041 ctgtaaaatc aaaaattgcc atcgaagcat tttctacata atgtcgtgta tctcttacct
     2101 catccacctt aatcagataa gaagataagg tatgccagac tccatcttgc aaacggacct
     2161 taaccgtaaa atcactattt aaagcaactc ctgcgggagc cttccaagtt gcaagtgtgt
     2221 ctttagcaaa gatacaagtt gcaccaccta ataatgcagc taataataag gaccaatatt
     2281 tcttcatgat attatcgaat aaaattcttt tatagtatta cgaacaataa agacgattca
     2341 cctattctct atcaaagata tttatgaaaa ctcgcaaaac aacaatcgtt caattaaaac
     2401 aatgatatgt ttattcatct aacaatgatt cttattgtac agccaataac gtcaattcgg
     2461 tggttattcc agattgcacc gcttttccgt caatcaccat cttacagggg gcagaagaaa
     2521 gaatatacca ttttccctgc ttcttttcga gcagcacatt agcagcctcc gaagtctgga
     2581 tactgatacc ggatgcaatc agttgcgttc cgttccctat aaacagcgtc cggtttcccg
     2641 catattcgtt actgattacg gcatagtccg ctttcacttt cattccctga taggttgcgg
     2701 tctgcgacga atccgtcaaa gagaaaatat ggtcagtacg cccgttttta ctttccacac
     2761 agataccggc aaaatctttc aagccaggct cttccgcatc aaagtaggag actgactgaa
     2821 tagccgaagg ctctttctgc gtacttggtt cataaacagc aacaaaagga cgattccatg
     2881 cttctccatg ctgccgggca acgaaggtga gagttggctg ttcctttata ttataaggca
     2941 tatggggagt ccggctcaat ccttcggtca tcggtgacag tgcggtgaac acttcccgtt
     3001 ccggttctcc tttcatccag agattcatgg aaatatcatc tccgccttta tccttcatat
     3061 cgatggtaaa agtcactttc acatcctgac cggtggtagc cactttctta tcatataagt
     3121 aggaataagc ataaagatgg gcacctgcaa aagcaagttc ttcggtaggc tgcaaattca
     3181 agtccgtgcc gttggcagcc gttagtgtca ttgtctgacc tagattatgg tagaaataat
     3241 cgtgcatttt atcgcctccc cgctctttcc ggctgcggaa tacatccaca taataccctg
     3301 tctccgggcc ggtagtaaca atgcccatca gtcgagtctg atccgccctg ctctccggct
     3361 cacggaaagc tacctgacta taggtgacgg aagtaaatcc tttacccggt tccgccgaag
     3421 ccggaaaaca ggaaagcaaa tcgaaagaat gattactttt catcaccgga taactggaaa
     3481 tgccatctac acaaaccgta ttatggctgg ggaattgaga gtaatattcc gcatagtcca
     3541 gaccgctata cagaaaaagt ccgatacccg catccggtcc cagcacatat ccttttccgt
     3601 aaagctccat cgaaatgcca ttcgcgtgca tatgattgcc ttcacttgcg ttgagagaaa
     3661 tcatcagact gttgcgcgga tgcatcccgt tgcgctgtac cagccacgat acgttggggg
     3721 catagaacag aggagataca taatcctcga ttttccccgc ctccaccttc gggtccagca
     3781 ccaacggctt gtcctcaaag aaagaattga cagaagcccg tacattcttc ttgccacttt
     3841 tttcgctgcc ttcctccgga ttcagacatt tcagcaaagc ggtgaagtaa cgttcctgct
     3901 ctttctttcc gtttgcctgc gcattctgta tcatccggat aaagaagttc gtacttaagt
     3961 aacttggatg cgtatctccg aaaccacaga tcatccggtt cggaaaaaga tactgcggag
     4021 tggccgctac ggcttttgcc agcacaggca ttgcctttac caagtcatac tgcagattat
     4081 ggtcaaactg atgggtgaag ttcgcgtaat cattgatgac tacactgctg tatcccggac
     4141 attccgccca tattcccgtt tcggagtcaa agccgtaatc ggccagcttg gtcagactcc
     4201 actggcggat gctcgaacgg ttcattacgt agtcaatata gtattcgcgt cctttcccgt
     4261 ccgcatactc ttcattatct tccagcacca gtcccacgtt catgatatat cgtgcctgca
     4321 ataaatccca gttgttatga gggactccgt tggtgataat attatccgcc catttcttca
     4381 atgcgccggc ataaatcatc atcttatccg gatagttgga ttgcagataa tgatagagaa
     4441 agtcatacaa agggacaacg atatgcaaag catcctcatg gatcacttca aaagaagtca
     4501 gccccaccag tgtctgctga tgcccgtgat tcaggtcaac aggaacattt ctgtaataga
     4561 ttcccgtcat ataagtatcg aaaacaccgg cagccagccg ggcatacttt tcttctcccg
     4621 tcatccaata gaggaaagcg gcgtcacggg caattcccag aatctcacag ttcagactct
     4681 caatattgcg cccggtcttg gacggatgca cactttcctg cggacggcct tccaaggcat
     4741 tgttgcagaa agtcacgttt ccttccgcac tatcgtcata aggtactaca tcttccagtt
     4801 taggtcgacc atgcgtagcg gccgtccctc gtgttccggt atagcgaact gtcggggcag
     4861 gtgccttcgc gcctccggca tggtcgaaca cctcaccttt cacgtacact tccgttgcat
     4921 gcgacttcca gtacatggcc aaacgggata ataaccagtc cggctgactt tccgtacgtc
     4981 gcgtatatac ttccgtccgt tctttcaact tgttaaagac atcttgtgcc catgcttcct
     5041 tcttgatcaa cttccatgtt tctttttttc cttccggggt agtcagcact ctcggatgat
     5101 cctgcggcat cttctccggc aacggaatct cctgcccgtg cgcattcagg aaaaaaagca
     5161 cacacaatcc taacaaaatt cgtctcatac ttccatttct tatttacgtt tgctacgtat
     5221 ttaatacgaa aataaggaat tatttaccta actggtatca gaaaacccgt ttttattttc
     5281 accggtacgg actgccttca tactccggac attcaagtat actcaaaaaa gatagcctgc
     5341 aagcatacca cttacaggct atcacaatcc ccttttttcc ctttgtatca gggaggcaac
     5401 ttacgtttcc ccgtccccgc cggaactctt gctgtacatc cttgccatca agctatatat
     5461 acttcataca aggagcattt ccccattcag atacagtacc ggcaggtccc cataagtcac
     5521 tccacaatgt tcttgcgaat ctccccaact atcgttggat tcatatgggt atccgccctt
     5581 tttcgatgcg aagataattt ttttatgcta ctattatagt taacaccgtc tattaaaagt
     5641 gttaaaaata aagatttcat accatacttc tgcaagccgg caccaaagaa gaatatttat
     5701 tttctctaaa caaagcgtta attccgaaca aagaattata tttgcagaaa tctaacaatt
     5761 ctgatactta tgaaaatact atctatccat gatttgcaaa taatcaggaa gagagcggag
     5821 caccatcttt cattgcgcga agaaagtaat gaaaaggttt ccgaaaaatg ttgcggactg
     5881 gcgtccggaa cagcacacct ccagattctt atttgcggag gtaccggttg taaagcctct
     5941 tccagtcagg gcatcactga aaatcttcaa aaagccattg aaagaaacgg gataaccgac
     6001 aaagtagacg tcatcacagt aggctgcttc ggcttctgcg aaaagggccc catcgtaaag
     6061 atcattcctg acaatacgtt ctatacccaa gtcactcccg aagatgcgga ggaaatcatc
     6121 agcgaacaca tcatcggagg acgaagaatc gaacggctac tctacataga cccgaagacc
     6181 gaacaaactg tcagtgactc caaacacatg gacttctacc ggaaacaact ccgcatcgcc
     6241 ttgcgcaact gcggattcat cgactccgaa aatatagaag aatacatcgc ccgtgaagga
     6301 tacttcgcac tggccgactg ccttctcaac aaacagcctg ccgacgtcat cgacgtcatc
     6361 aaacgctccg gcctgcgggg acgcggtggg ggcggtttcc ccaccggctt gaaatgggaa
     6421 tttgccagta agcaggtatc ggacgtaaag tacgttgtct gcaacgccga tgaaggcgac
     6481 cccggcgcct tcatggaccg ctccatcatg gaaggcgacc cgcactctat tgtagaagcg
     6541 atgtgcatct gcggttactc catcggttcc tccaaaggac tggtctacat ccgcgccgaa
     6601 tatccgctgg ccatcaaccg cctcaaaaaa gcgattgagc aagcccgtgc atacggatta
     6661 ctgggagacc acatcctggg gacagatttc agcttcgaca tagagatccg ttacggagca
     6721 ggcgcgttcg tctgcggcga ggaaaccgcc ctcatccact cgatggaagg caaacgggga
     6781 gaaccgacct tgaaacctcc tttccccgcc gaatccggtt atctgggcaa accgaccaat
     6841 gtgaacaatg tggaaaccct cgccaacatt cccattatcc tgaccaaagg cgccgaatgg
     6901 ttcgcctcca tcggaacaga acgctccaaa ggcaccaaag tcttcgctct tgccggaaag
     6961 atcaacaatg tcggactgat cgaagtaccg atgggaacta ccctgcggga agtaatctac
     7021 gaaatcggcg gaggcatcaa gggaggaaag aaattcaaag ccgtacagac aggcggtccg
     7081 tcagggggct gtctgacgga gaaacatctg gatactccca ttgacttcga caacctgctg
     7141 gcagccggtt ccatgatggg atcgggaggc atgatcgtga tggacgaaga tgactgtatg
     7201 gtatccgtcg cccgtttcta tctcgacttt accgtcgaag aatcctgcgg taaatgtacc
     7261 ccatgccgta tcggcaacaa acgcctgctg gaactgctga acaagataac ggaaggacgg
     7321 ggcacggaaa aagacctgga cacgcttgcc accctcggac gggtgataaa ggacacggca
     7381 ctctgcggac tgggacaaac gtctccgaat ccggtactgt ctaccctcga caacttccgt
     7441 gacgaatatc tggaacatgt cagagacaag acctgccgcg ccaaacaatg caagtccctg
     7501 ctgacctata ccattaatcc ggaactttgt atcggttgcc acctgtgtgc caagaattgt
     7561 ccggcggatg ccatcagcgg cttggtacgc aaacctcatg tcatcaaccc cgagaaatgt
     7621 atcaagtgcg gcatgtgcat ggcacgctgt aaattcaaag ctattcttgt ctgctaaaat
     7681 ctactgctat ggaagaaaaa caaattaccc tccagataga cggtcacttt atcaccgtac
     7741 ccgaaggaag cacgatcctc gaagccgcct gcaaaatcgg catcaacata cctacgctgt
     7801 gtcacatcga cctgaaagga acctgtatca agaacaatcc cgcttcctgc cgcatctgtg
     7861 tagtcgaagt ggcaggacgc cgcaatctgg ctcccgcctg cgctacccgt tgcacggaag
     7921 ggatggtagt gaaaaccagt accctacgcg tgatgagcgc ccggaaagtg gtagccgaac
     7981 tgatcctttc cgatcatccc aacgactgtc tcacctgtcc caaatgcggc aactgtgaac
     8041 tccagacact ggcactgcgt ttcaacatcc gtgaaatgcc gttcaacggc ggcgaacttt
     8101 ctccccgcaa acgggaagtg acctcctcca ttgtgcgcaa catggacaag tgtatcttct
     8161 gccgccgatg cgaaagcgtc tgcaacgatg tacagacagt cggcgcactg ggagccatcc
     8221 gccgcggatt caacacaacg atagcccctg ctttcgacag aatgatgaag gacagcgaat
     8281 gtacctactg cggtcaatgc gtagccgtat gtccggtagg cgcactgacc gaacgggatt
     8341 acaccaaccg ccttctggac gatttggccg accccgataa aatcgtaatt gtccagactg
     8401 cccccgccgt acgtgccgcc ctgggagaag aattcggctt gcctcccggc acactggtaa
     8461 ccggaaaaat ggtttacgcc ctccgcgaac tgggtttcga ctatgtattc gataccgact
     8521 ttgccgccga cctcaccatc atggaagaag gttccgaaat cctgaaccga ctgacacgct
     8581 atctggacgg agataaatcc gtccggcttc cgatcctgac ttcctgctgc ccggcttggg
     8641 taaacttctt cgagcaccac ttcccggata tgctggatat cccttctacc gcccgttctc
     8701 cgcaacagat gttcggctcc atcgccaagt cttactgggc agagaaaatg ggaatccccc
     8761 gcgaaaagct agtagtcgtc tccatcatgc cctgccttgc caagaaatat gaatgcgacc
     8821 gcgacgagtt caaagtaaac ggtgtccccg acgtcgatta ctccatctcc acccgcgaac
     8881 tggcacgcct gataaagcga gccaacatcg gctttaccct cgtgctggac agcccgttcg
     8941 acaaccctat gggagaatca accggtgccg gtgtcatctt cggtacgacg ggtggtgtca
     9001 tggaagccgc cctgcgctcc gtttatgaaa tctacaccgg acagccgctg aagaatgtca
     9061 actttgaaca ggtacgcgga ctgagcggag tccggcgcgc caccatcgac ctgaacggat
     9121 ttgaactgaa agtaggcatc gcacacggac taggcaacgc aaggcactta ctggaagata
     9181 tacgaaacgg acataatgaa tatcatgtca tcgaaatcat ggcatgcccc ggcggctgca
     9241 tcggaggtgg cgggcaaccg ttgcatcacg gcaactcgga cgttctctac gcccgtgcca
     9301 acgcccttta ccgggaagat gccaacaaac ctttgcgcaa atctcacgat aacccatata
     9361 ttcagaaact gtatgaagaa tatctcggca aaccgctggg tgagaaatcg gaaatgctct
     9421 tgcacacgca ttatttcaac aaatcgattg attaacttta aacaagtact attatgtcag
     9481 atatcaagct agcctgcgat gtggtggaac aagtcaagac gatttgcgac aaacacggga
     9541 acaatgcggg cgaattaatc aatattttgc atgaagcgca acatctgcac ggctatctgc
     9601 ccgaagagat gcaacggatc atagcctcca aactcagaat ccccgtgtcg aaagtctacg
     9661 gagttgtgac attctacacc ttctttacaa tgactcccaa aggaaagcat ccgatttccg
     9721 tctgcatggg cacggcgtgc tacgtacgtg gttcggagaa gttgctggaa gagttcaagc
     9781 gggtactcgg catcgaagtc ggagaaacca cccccgacgg aaagtattcg ctggattgcc
     9841 tgcgctgcgt aggcgcctgc ggactggctc cggtagtgat gatcggcgaa aaggtgtacg
     9901 gacgactgca accggtggat gtaaagaaga ttatcgagga actggaataa gtctctccta
     9961 cccttcaaaa gaggatgtga cgtatcgggt acccgatatg tcacgcatct tctttggggt
    10021 catatcccca cttcacataa accgctcccc aggcaaatcc tgcaccgaat gcggtaaata
    10081 tcagattatc gcctttcttc agtttcttct caaaatccca gatgcaaagc ggaagcgtgc
    10141 cggcactggt attgccataa cgttcgatgt tgaccatcac tttctcggac ggtacttcca
    10201 accgttgcgc cacagcggta atgatacgct ggttagcctg gtggggaatc acccaatcaa
    10261 tatcctcctt agtcaagtgg tttctggcga taatagcttc acaggaatcc gacatattcg
    10321 ctacggcata cttgaacacc gtgcggcctt cctgataaat ataatgcaga tgatgatcca
    10381 atgaataata ggaaggagga catacggaac ctcccgcttt tatatgcaga aaaggcagcc
    10441 ctttaccatc cgttctcaac accgaatcca tgatgccgac ctcttccgta gtcggttcca
    10501 gcataaaagc ggccgcaccg tcgccaaaga tagggcaagt ggcacggtcc gtataatcga
    10561 ttacggatga catcttatca gcacctacaa taataatctt tttatatttc cccgaacgga
    10621 taaaattcgc tcccgtttcc atcgcataca ggaaaccgct gcaaaccgcc tgcatatcga
    10681 aagcgaaagc attcttcagc cccagccttt cgcacaagat agatgccgtt gaaggaaaac
    10741 gatagtccga agtagtagtg gcgacaatga ccagatcgat atcatcggga cgactctttg
    10801 tgcgttgcat caactgcttg gcggccttac gggccatata cgaagttcca agcccctctt
    10861 cattcaagat atgtcgttct tttatgccga tacgccccat gatccattcg tcggtggtat
    10921 ccaccatttt agaaatttca tcattagtca gcacataatc gggcacatat cccccgaccc
    10981 cagtaattac cgcatttatt ttatccatca agtctatttt cagaattaca aaaatgtgat
    11041 atctcaaaaa aaatatcggg cgcaaatata cagaaaagag aatgatatac aagagaagag
    11101 tactagaaat accagacact ttgacctatg aaaagaactt ttggctaaag aacgagaagt
    11161 tttgactaaa tttcagattc agcggagaga gcgggattcg aacccgcgat acacttttgg
    11221 cgtatacacg ctttccaggc gtgcctcttc aaccactcga gcatctctcc tttcaaaaaa
    11281 ctcaataaac actaagaaaa cgctcccgtt ttcgtttcac aacatcggag gcgtcgccct
    11341 ccataaaaac aaaaaagcag cccaaaagct gcttttcagc ggagagacag ggattcgaac
    11401 cccgggtacc tcgcggtaca acggttttca agaccgccgc aatcgaccac tctgccacct
    11461 ctccaaaact tccttgtcag aagtgctttt cgttaaaagc ggtgcaaagg tacgaagata
    11521 ttttaaactt gcaagagttt tcactaaaaa tttaatctaa tcttttccta aggatagcaa
    11581 ttaataggta ttttatgttg aaaagcataa aatagagcat atttatgctg attatatgaa
    11641 aaatgattgt aactttgtgc gctctaaaga aaaggataac tacaacctct aattttatca
    11701 ttttatggaa ttaaacaaga tctttaaaga cggtctttgg agcagcgaaa tcaacgtcag
    11761 agatttcgta agtcataaca tcactccgta ttacggagat gcttcattcc tcgaaggacc
    11821 tacagaacgt accaaagccg tatggaaccg ctgcctcgaa gcactggcag aagaaagaga
    11881 aaacaacggt gtccgctcat tagataatgt taccgtatca accatcactt cccacaaggc
    11941 cggatatatc gacaaggaaa acgaactgat cgtcggcctg cagacagacg aacttctgaa
    12001 acgtgccatc aagcctttcg gaggtatcaa cgtagtcagc aaagcctgtc acgaaaacgg
    12061 cgtggaagtg gacgaccgcg taaaagatat tttcactcac taccgcaaga cgcacaacga
    12121 cggagtattc gacgtatata cggaagaaat ccgttccttc cgttcgctgg gattccttac
    12181 cggacttccc gacaattatg cacgcggacg catcatcggt gactaccgcc gtatggctct
    12241 ttacggcatc gaccgtctga tcgaagcaaa gaaggaagat ttgcacaacc tcaccggtcc
    12301 gatgacagag gcccgcatcc gcctgcgcga agaagtggca gaacagatca aggcactgaa
    12361 agacatgaaa gtgatgggcg aatactacgg tctcgacctg agccgtcccg cttacacggc
    12421 acaagaagcc gtacagtggg tatatatggc ttaccttgcc gccgtcaaag aacaagacgg
    12481 tgccgctatg tcactgggta acgtttcttc tttcctcgat atctatctgg aatatgaact
    12541 gagcaaagga accatcaccg aatcgttcgc gcaagagctg atcgaccagt ttgtcatcaa
    12601 actgcgtatg gtccgccacc tgcgtatgca atcatacaac gacatctttg caggcgaccc
    12661 gacctgggta accgaatctc tgggcggacg tctcaacgac ggacgtacca aagtgacaaa
    12721 gacctccttc cgttttctgc agacattgta caacctcggc ccttcaccgg aaccgaacct
    12781 gaccgtactc tggagcccgg aacttccgga aggattcaaa gaattctgtg caaaggtttc
    12841 tatcgacact tcttctatcc agtacgaaaa cgacgacctg atgcgtgaag tacgtcagtc
    12901 cgacgactac ggaatcgcct gctgcgtatc ataccaggaa ataggcaagc agattcagtt
    12961 cttcggtgcc cgttgcaacc tggccaaagc cctgttgctt gccatcaacg gcggacgttg
    13021 cgagaatacc ggtacagtca tggtgaagaa catccccgta ctgaccagtg acacgctgaa
    13081 gttcgaagaa gtaatggaca actacaaaaa agtgctgacc gaaatcgccc gcgtatataa
    13141 cgaagcgatg aacatcatcc actatatgca cgacaagtat tactacgaga aggcccagat
    13201 ggctcttgta gatacgaacc cgcgcatcaa cctggcttac ggtgtagccg gactttccat
    13261 cgccctcgat tcactgtctg ccatcaaata tgcgaaagta actgcccgcc gcaacgatat
    13321 cggcctgaca gaaggtttcg acatcgaagg agaattccct tgcttcggta acgacaacga
    13381 caaggtagac caccttggcg tagacctggt atacttcttc agcgaagaat tgaagaaatt
    13441 gccagtttac aagaatgccc gtcctaccct ctccttgctg actatcactt ccaatgtgat
    13501 gtacggcaaa aagaccggtg ctactcccga cggacgtgcc aaaggtgttg ccttcgctcc
    13561 gggtgccaac ccgatgcacg gacgcgacaa gaatggtgcg atcgcttctc tgagctctgt
    13621 agcgaaactt cgttaccgtg actcacagga cggtatcagc aacaccttct ctatcgttcc
    13681 gaaatcactg ggtgctacgg acgaagaccg tatcgagaac ctcgtaacga tgatggacgg
    13741 ttacttcacc aaaggtgctc accacctgaa cgtaaacgta ctgaaccgtg atatgctgta
    13801 cgatgccatg gagcatccgg aaaactatcc gcagctgact atccgcgttt ccggctatgc
    13861 cgtaaacttc gtgaagctga gccgcgaaca ccaactggaa gttatcagcc gtagcttcca
    13921 cgaacgtatg taatctatta ctctatatga tgataaacgt acattcatac gaaagtatgg
    13981 gaacattcga cgggccgggc
//
