LOCUS       gnlProkkaLHDDDFDO_379  11635 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHDDDFDO_379.
ACCESSION   gnlProkkaLHDDDFDO_379
VERSION     gnlProkkaLHDDDFDO_379
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:38:15
            Original ID  :: gnl|Prokka|LHDDDFDO_379
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11635
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..423
                     /locus_tag="ctg379_1"
                     /transl_table=11
                     /translation="MLTHLPKGSILTPHPKELERLVGKCQDSYERLMKACELAHTAKVH
                     IILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPAEDAAKIGTY
                     IHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     protocluster    1..11635
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1957:2302]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1958..2302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11635
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11635
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             497..1561
                     /locus_tag="ctg379_2"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELLAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             1583..1864
                     /locus_tag="ctg379_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(1812..1937)
                     /locus_tag="ctg379_4"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKRLPTGGQHILSVRP"
     CDS             complement(1958..2302)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg379_5"
                     /sec_met_domain="PF05402 (E-value: 5.3e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.2e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             complement(2346..3005)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 63; E-value: 3.2e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg379_6"
                     /transl_table=11
                     /translation="MKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLMVQKYNVD
                     PKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFALPILNIWW
                     FATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVPLLIGWVL
                     NSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEANIQK"
     CDS             complement(3024..3734)
                     /locus_tag="ctg379_7"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGL"
     CDS             complement(4025..4420)
                     /locus_tag="ctg379_8"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             complement(4427..5200)
                     /locus_tag="ctg379_9"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(5205..5732)
                     /locus_tag="ctg379_10"
                     /transl_table=11
                     /translation="MNWIKKIARPLILIVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(5719..6960)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg379_11"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(7084..8178)
                     /locus_tag="ctg379_12"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(8183..9220)
                     /locus_tag="ctg379_13"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFGCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTREA
                     EPTNK"
     CDS             complement(9238..10275)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg379_14"
                     /sec_met_domain="PF04055 (E-value: 1.2e-17, bitscore: 54.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSKYPLLGMTLIELQSLVKRLGMPGFAAKQIASWLYDKKVTSID
                     EMTNLSLKYRELLKQNYEVGAEAPVEEMRSVDGTVKYLYPVGENHFVESVYIPDDERAT
                     LCISSQVGCKMNCKFCMTGKQGYSANLTAHQIINQIHSLPERDKLTNVVMMGMGEPLDN
                     LEEVLKALDILTGSYGYAWSPKRITVSTVGLRKGLRRFIEESDCHLAISLHSPVTAQRA
                     ELMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCR
                     MNLIRFHSIPGVALEGADMDTMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQE
                     ENNKS"
     CDS             complement(10414..11634)
                     /locus_tag="ctg379_15"
                     /transl_table=11
                     /translation="MVDLFYNKTAFPSDVVARLDSASVGSVYGPYYNGADNTINSFKVV
                     AKTAAADSIEFRQIQVFAEDALKTKALADSIYTAIKGGANFADLAKKYGQTGETNWMSS
                     AQYEGAQIDGDNLKFISAINNTGVNEVVNLPLGQANVILQVTNKKAVKDKYKVAVVKRE
                     VEFSKETYNRAYNDFSQFIAANPTAEKMIANAEEAGYKLLDRRDLYSSEHTIGGVRGTK
                     EALRWAFSAKPGDVSGLYECGESDHMVAVALVGVTPEGYRPLKAVQDQLRAEIVKDKKA
                     EKIMADMKAANATSLDQYKAMSGAVSDSLKLVTFAAPAYVSALRSSEPLVGAYASVAEM
                     NKLSAPIKGNAGVFVLQMYGKDKLSDTFNAKDEEATLANMHARFASRLMNDLYLKGKVK
                     DTRYLFF"
ORIGIN
        1 acgctcaccc atctgccgaa aggttccatc ctcacccctc acccgaaaga gctggaacgc
       61 ctggtcggca aatgtcagga ctcatacgaa cgactgatga aagcctgcga actggcgcac
      121 actgccaaag tacatatcat tctgaaggga gcttattccg ccattatcac ccccgaaggc
      181 aaatgttact tcaaccagac cggtaatccc ggtatggcaa caggaggcag cggagatgta
      241 ctgacaggag taatccttgc actccttgcg caaggctatc ccgccgaaga cgccgcaaag
      301 atcggtactt acattcacgg attggccgga gacatcgccc agaaaaaaca gggcatgatc
      361 ggattaatcg caagtgatat cgtgacctgt ctgccgacgg catggcgact tgtaagcgaa
      421 taaaagttaa gaacttacgg tttattcaat aacttcatta actttgtttt tcaaaatcag
      481 ctaaaaagaa ccgaatatga aaaagttaat catagcaaca ggactactaa tggcaacttc
      541 cgcctatgcg cagaccgaag tgctgacagg agtgacgcga ggaaaagact acggagtagt
      601 gtacgccctc cccaaaaccc agatagaaat agaaataaaa gcaaacaaag tcaactataa
      661 gccgggtgaa ttcagcaaat acgccgaccg ctacctgaga ctgaccaacg tctctgccga
      721 acccgaagaa tactgggaac tgaacagtgt caaagtgaaa cctgtaggtg taccaaacag
      781 cgaagctact tatttcgtca aactgaaaga caaaaccgta gctcctctta tggaactgac
      841 tgaagagggt cttatcaaat caatcaacgt cccctacagc agcaacaatg caaagaatgc
      901 agcaaacaat gccgttgctc cccaacgaaa agccaatccc cgcgactttc tcacagaaga
      961 aattctgatg gcaagttcaa ccgccaagat ggccgaactg ttagcaaagg aaatctataa
     1021 tatccgcgaa agtaaaaacg cattattgcg cggacaagca gataatatgc cttcggacgg
     1081 cgcacagctc aaaatcatgc tcgacaacct gaatcttcag gaagaagcca tgaccgagat
     1141 gttttcggga gtccgcaata aagaagaaaa gacatttact gtccgcctca ctccggataa
     1201 ggaattcgac aatgaggtag ctttccgctt ttcaaagaag ctgggtatag ttgccaacaa
     1261 cgatttggca ggcactccat tctacatcag tctgaaagac ctgaaaacgg tgaagattcc
     1321 gcaagaggac ggaaaaaaga agaaagagat ggaaggcatt gcttataacg taccgggaca
     1381 ggcaatggtg acgctgacgg acggcaaaaa gaaattgtat gaaggagaaa tacctgttac
     1441 tcagttcggt atcatagaat accttgctcc ggtattattc aacaagaact cgaccatcaa
     1501 agtttacttt gatccggtga ccggtggact actgaaagta gatagagaag aaagcaaata
     1561 aaacctctaa aaaaacaaaa cgatgggtgg cgaaggacat atgctcgaca tgatacgtcg
     1621 gctgaaagac ggcaaagaag cctcccgctt acgccgtgaa cggagaaatg acaagttagg
     1681 gcgacttaga agaaacaacg acccttatct tctgccggat acgactccgg aagagatgga
     1741 acgcatcatc aaggattcgg aaaagaaaaa agaaaaagat aacagctatt tcgtatgggg
     1801 aacgctcatc attatgggcg tactgatagg atgtgctgtc ctcctgtggg caatcttttt
     1861 ttaatggata atggaaaatt gataatggat aatgaacgta tgggataata ttccagctgc
     1921 tcaacctcat tatccatttt ccattatcaa ttatccatta atcaattatc catttaataa
     1981 atccgtcttt ctgtaattgg gaaagatagg tagatacacg agactcgtag cctgcttcat
     2041 gctgaaagtg gtctgcgagt ttttctataa tctcacgaac cgtccgctgg ccgtctatca
     2101 ggttccatac ggccgtaccg tgttcttcca gacgcacatg aatatctttg gacattcctt
     2161 tcggcaataa ataacgactc atccacgaac gtttaaaacg agggaaggag agcacaatag
     2221 tctccccttc ctgttcagct ttaatatgtt cgttacgaca agggatcacc tccaggaggt
     2281 ttattttctc tttcgtagcc atatcttttc tcttttatat cttttcagat agaatatata
     2341 ctggattatt tctgaatatt tgcttcttcc agtccgtagc ctttcttctt gttttctgct
     2401 ttcagcatca aggcaacaat cagggcaagt acaccgaaca tagcaaaaat agccatcggc
     2461 aaggtataat cataagtctg tgcaccatct acaaccggac ctttgcaata agaattcaac
     2521 acccatccaa tcagcaaagg cacgcccatc aatccccagt tctgtaccca aaagatcaac
     2581 gcataagccg ttcccaactg tttctccgga ataatcttcg gaaccgaagg ccacattgcc
     2641 gaaggaacca atgagaaagc aaatcccaga ataatcatga tcaccgttgc aaaccaccag
     2701 atattcagaa taggaagagc gaacatagtg tgtacgaaaa tcagcatcac cgacccgatc
     2761 accatcagcg tggctccctt accgatacgg tcatacaatg acccgaacaa cggtgtcagg
     2821 atgatcgcgc caatcggcag caatccggga atcgttcccg caagtttcgg atctacattg
     2881 tacttctgta ccatcaaatc agccgcatac ttgatgaagg ggaatacagc cgaatagaac
     2941 aatacgcaca gtaatgcgat cagccagaat cctttgttgg taatgatata tacgatgtct
     3001 ttcatgcgga aaggttcttc cggttacagt ccttccgcat ccagtgaagc atccagtttc
     3061 ttatcataga aagtatagat gaagaatgcg atggtaccta cgcacagcat gacgagacag
     3121 aacagaatcg gagcgggaat attggtatgg aatacgccgc tctcatccgt agacccgaag
     3181 aagtctgcca aaggaacggt aagcaccatg gccaaagttg ttccaatacg cgcggtcgcc
     3241 atttccagtc ccatagcgag agccatctct ttgcctttaa accacttcac gataatcttc
     3301 gaaacggtga tacccgcaat ttcgactcct acaccgaaaa tagcatagcc caatgcagcc
     3361 aatgtgactt gcatcttgaa tccgaaaagc atcgcacctt ccgggaaagt agtagtaata
     3421 gcataatatt tcaatccaca accaaacacc atcaataaac aggcacccat tccggtgaag
     3481 cgtactccca tcttatccag aatgatacca ccaaagatga gcatcagcag gaatacatta
     3541 aaccagccat aagcactggt gaaaaaaccg taatctaaac tgtcccagag aagttctttt
     3601 tcaagcatgg gtttcagagg agacataacg tctgtgagga agtagccgca caacatggta
     3661 aaagcgacta atgctagaac actccaacgc agcactgcgg agtcattcag cttttgtttc
     3721 aattgttctg tcattgtaat atttaaaagg agttaataat ctcgtaacgg gcaacaaagt
     3781 taactaatta tcatttgttt tactaaaaaa ggagaacatt ttataagaaa aaggacatct
     3841 gaccggatat tcctgtatga agaagagcag accggaccca ataataaaga taggcgcgaa
     3901 ccacacgtat tacacaattc tattagaatc tcttgtaatt cgcgtaattc gcgcctataa
     3961 tgaagagaac gggtcaaaaa gcccgttcac tcaataagtt taaaccgaat atcctgtcac
     4021 tgaattattc tgctgcagga gcaggagttt cagtagccgg agcttctgtt gctggtgcag
     4081 actctgcagg agcagtagcg tctgtctgag gagcagcagt accggtaggc atattatacg
     4141 gattggtttg ttgttctttc tgtgcttgtt ccaacaatac atctttagct gcagaagaag
     4201 aaggaacaac gtaagcagta gcaacgctca tcacaaccat gaagatagcc agaccccaag
     4261 ttgctttttc cagaaaatct gtagtcttgc gcacgcccat gatagcgttt gatgaagaaa
     4321 aaccagaagc aagtccgcct ccttttgaat tctgaatcag cacgatgaag cacatcagca
     4381 aggctgcaat caccattaag ataatgaata ataagtacat ttttagttat tttgaattag
     4441 cgttaataat caatttctcc aaaaatctga tttggtctgc aaagtaagca tttttttttg
     4501 gatatttcaa gcttaatttt ttaattattt caagagcttt tgaatatcgt tgctgtttaa
     4561 catagatttt tgccaaagtt tccgtaaaac agctgtcatc ttcctcttct tccttcatcg
     4621 tttcttcttc ggtaagttcg tccgaagagg ttggcgaaga tggcatttct tctcttaaag
     4681 gtttcttgca gaggggagag tcgctctcgc tcttttctat aaagtcgtca atcagttcgt
     4741 agcctttgag tttgggcgtt tcttcggccg actgttccgt ggccggagtc tcctccaaaa
     4801 gataagaggt gtaatccatc gaatagtcga agctggtccg ggcagtcacc tcttcgggta
     4861 ctgtggacaa gaaagcgtcg atcaatgcta atgtgcggtc tacggacggt tcgtctttca
     4921 gcacctccgt gagaggtact ccctttttcc gtgcttgcac atcatagcgg tcaccttcaa
     4981 tcaaccggaa caactgccgt ctgtctgcaa tgtaaagaac tgctttccgc agttctccac
     5041 caaaactaat atcatggaga atatacagat tcttcagata cagcagacga agtgactgaa
     5101 aatacggata cctcgcaaga agattgcgca gttcgtacaa agtatcccta ttcagcgtct
     5161 cgggatgctg aatccattgt tgcaagttaa cagaagtcat taaattacca gtttgctaca
     5221 gttgcattaa atatttggtc ggttatctct ttactcattt ccgctattaa tccatcctgt
     5281 acggccgtca gcagctggct ggaatcatag gtacggaaag ctgagaattg ttgttcgaag
     5341 tcttcggcgt gatttgtgtt gttgacaaag cgtacattga ccgtgatggt cagcttcgtt
     5401 tccgaagagt aaccatcggc agacactgcc tggttatact ggttgtagcc cgtaatttca
     5461 ccgtcaatct gcagatccgc attctggttc ggtttcagca gttgcagacg ggtctgtctg
     5521 atgaagatat ctttcaggtc ttcattgaac ttggtagcca gcggagcata cacatactcc
     5581 gacttaatcg ggaaatcagc aatcgaaatg gtcttcacct tatcgtaatt gatagaggag
     5641 ccattaaact tataggacac actacaggcg atgatgactg ccggtaaaac aatcagtatc
     5701 agcggtcgtg ctattttctt aatccaattc atattctttt atttttctgt aaagggtacg
     5761 ctcggagata ttcagatcct ttgccgcact tttccgctta ccatgatgcc tctcaagcgc
     5821 tttacgtatc atttcttttt ccacttcatc gagcgaaagg gtttcttcca catattcttc
     5881 cgtgtcctga atatcgtcat cgtcttcttt gggacaaaca gacggttgct gcacagcatg
     5941 gataatggcc ggcacagatg gttggtgcgt cgtcgtcact accggagtag ccactacctg
     6001 tcccatctgt ccgacttgtc ccgcacgttc ggccatcata ttgtgcacca tcttcttcag
     6061 ttccgccact tcctggcgca tatcgaacaa gacagaatat agtatttcgc gttcgctctc
     6121 aaagctcttg ctctcgcgtg tgccgaacag tgccggaagg cgttgggtat tctgtgccgg
     6181 aagataggtc tgcagaatcg cagccgttat ctcacggttt gtttctataa tcgaaatctg
     6241 ctctgtgata ttcttcaact gccggacgtt tcccggccac ggataagcaa gcaatatctt
     6301 cttggcatct tccgtcagct ggatagccgg catccggtac ttttcggcaa agtctgcggc
     6361 aaacttacgg aacaacaaca gcacatcatc tccgcgctca cgcaaaggtg gtatctgaat
     6421 aggcaccgtg ttcaaccgat aatacaaatc ttcccgaaaa cgtccttcgg caatggcttg
     6481 tgtcaggttc acgttggtag ctgccacaat acgcacatcc gtcttttgaa ctttggatga
     6541 acctaccttg ataaattcac cgctttcaag tacacgaagc agacgcgcct gtgtaggcaa
     6601 cggcaactct cccacttcat caaggaagat ggttccaccg tcagcttctc caaaatatcc
     6661 tttccgctca ccaatagcac cggtaaatgc tcctttctcg tgtccgaaca gttcggaatc
     6721 gatcgtacct tccggtatgg caccgcagtt gacagcaata tactgtccgt gctttctccg
     6781 gctatattga tgaatgatct gtggaaaact ttcttttccg acaccacttt ctccggtaat
     6841 cagcacagac aaatcggtag gcgctacctg aatggcaaca tctatggcac gtgataaagc
     6901 ctcggtattg ccaataatac cgaaacgctg tttcacttgt tgtatctccg ctttggtcat
     6961 ctatcttaat attaagtaat aggtaataag tattaagtaa taagtattaa gtattaccat
     7021 cattatcatc tcgcttccat ccgcatggct aatacttaat acttattact taatacctat
     7081 tacttaatct tcgtctactg tatccagttt tagtttatca ctatcgtccc gtttctcgta
     7141 atactgcttc cgcaacgggt ttacccgtgc cgctttctcg cgctggcggt tgcggaatac
     7201 atcaatcgct acataaatag cctggcggaa agagtcttcg ctggccagtc ctttaccggc
     7261 gatgtcatag gctgttccat gagccggaga ggtacgtaca accggcagtc cggcggtata
     7321 gttcacaccg tcttccatag ccagggcttt gaacggagcc agtccctgat catgatacat
     7381 agcaaggatt ccgtcaaagt gagtataatt gcccgaaccc ataaaaccgt ccgcagcata
     7441 aggaccgtaa cagatgatcc ctttctcttc catttctttc atggcaggga taatgatttc
     7501 ctgttcttcc atacccagca gtccgccgtc tcctgcatga ggattcagtg aaagcactgc
     7561 aatacggggc gcaccgatac cgaaatcctg tttcagacaa cgatggaaaa tcatcagctt
     7621 ttcctgaatc agttccttgg tgattgttgt agcaatctcc cttaccggaa tatgcgtcgt
     7681 tactaaagcc acacgaaaat cgtttttcat caggatcatc agtgacttgt ttccattgcc
     7741 cagacgttct tcaatatact ccgtatgccc ggggaaagag aactcttccg actgaatggt
     7801 atgtttgttg atcggagctg tcacaatgac gtcgatcagc ccctcacgat actcttctat
     7861 ggcacgctcc aaagcaccca atgcagcctt acctgcttcg ggatcgggtt tggagaattc
     7921 cactttcact tcgtcatctg tacagttcac tacactcaga cggttgtatc cggcttcgga
     7981 agctgtgttg acaatgctga aattagcctg tacatccagt gctttacgat ggtaagccgc
     8041 tactttaggt gaaccgtaga taatcggagt acatagctca agcatggtag ggtctgagaa
     8101 tgtcttcaag atcacttcat aacctacccc gttgatatct ccttgggtaa tgccgattct
     8161 tattttgttt tcttccatgt ttttatttat tagttggttc cgcttctctg gttaccccca
     8221 gtggaatctg actctgctga ccttcttgcg gaagtttcag cgtataaaga gatgcttcca
     8281 tctggcgaac cagattgcgt ttcattttat cgggtgaata tacaaatatt tctgctgtaa
     8341 taatacgttg gttcttctga tccagacgag tatgggaaac gaacgggcca cccatgaagt
     8401 cacccttcat gcgccacaat ccacgagctt ccatcgtgta gtcattgtgc acgttgatcg
     8461 gacgaacatc ggtcagtaac gagtctgtcg acatatatac gccttcttta tatccgggga
     8521 tattggcttt catcacagaa tcgcgcttat gaacaaagta ttctttggtg aatgtatcct
     8581 tgtcagtata aggataagaa tacatcacga aattgcgatc cgcgctgcct gtattggtag
     8641 atgcccagaa gaagtcctct cctgtcttgg agttattcag ttcggaaggt atccagatat
     8701 cgcagccaaa cagactatct accttatttg agataaagtt gttgtgcttt tcctccagca
     8761 aagtaatctg acggttcatt tcagcgcgag tgaagaagtc gataatcgtc tgcttgtttt
     8821 cttcgacaaa cttctcaaac acttcttcgt tcggagcctg aatggtcagt atcatctgtg
     8881 gagaagcata aacgtctttc gcatacttga aagtaccttt ggtataaata tcttttatat
     8941 ctactatcac aatattacgg atcaacttca gcgtagaatc atagtccttc ggtgaagtat
     9001 acataatccg gaaagaaggt tccgactggg gcagtcccgg catgtcagaa tcaagcacat
     9061 catgcaaggc ccttccggcg gcacggtccc acactcccgc atctactaca accaacagtt
     9121 catacggacg accgctagag gtatgattcc cctttaatcc acaagaagca actacgaagg
     9181 ctaccagagc catgcttaaa taaaaaaagt actttttcat gatgttcgat ttttatatta
     9241 acttttatta ttttcctcct gtttcgcagt cgacagcata ccgcatgccg caaaaatatc
     9301 ctctccccgc gaagcacgaa tggtagtgaa aagcccgtgc gtggtcagat agtcacggaa
     9361 acgggtcatt gtatccatat cggctccttc aagggctact cccggaatag aatggaaacg
     9421 gatcaggttc atccggcaat ccagtccgcg aagcagtttg agtaactcct tggcataaac
     9481 ttgcgaatca ttaagcccct taaaaacaat atactcaaac gaaagtcgac gctgtttgct
     9541 aaaatcatag ttttttaaca gttccaccat ttccgtgata gaaaaggctt tctccgccgg
     9601 catcagttcc gcacgctggg cggtcaccgg agaatgcagg ctgatggcaa ggtgacagtc
     9661 gctttcttcg ataaagcgcc gcaatccttt ccgcaatccg acagttgaaa cggtaatccg
     9721 cttcggactc catgcataac cataggaccc agtcagtatg tccaatgcct tcaacacctc
     9781 ttccagatta tcgagcggtt cgcccattcc catcatgacg acattcgtca gtttgtcccg
     9841 ttcgggcaag gagtgaatct gattgataat ctgatgggcg gtcaggttgg cagagtagcc
     9901 ttgtttcccg gtcatacaga acttgcagtt cattttgcag cctacctgcg aagagatgca
     9961 taaagtcgcc cgttcatcat ccggaatata caccgactcc acaaaatgat tctcgcccac
    10021 agggtacagg tatttcaccg taccgtctac agagcgcatt tcctccaccg gagcttcagc
    10081 tcctacctca tagttctgct tcagtaactc ccggtatttc aacgacaagt tagtcatttc
    10141 atcaatcgaa gtcaccttct tatcataaag ccaggatgca atctgtttgg ctgcaaagcc
    10201 cggcattccc agacgtttca ccagtgactg cagctctata agcgtcattc ctaagagggg
    10261 atatttagac atcattcttt ctgttcatgg tttatatttg caaatgtaag gaaataaagt
    10321 cgatttccgt atagcaagga tgtaaaagtt agcaaaaaag gtcgttccaa agcatggaac
    10381 gaccttttgc agttatcgtt tttacgacta atcttagaag aacaggtaac gtgtatcctt
    10441 cacttttcct ttcagataca ggtcgttcat cagacggctt gcgaagcgtg cgtgcatgtt
    10501 agccaatgta gcttcttcat ctttagcgtt gaaagtatcg ctcagtttgt ctttgccata
    10561 catctgaagc acaaatacac cggcattacc tttgatcgga gcgctcagtt tattcatttc
    10621 agccacagaa gcataagcac ctaccaacgg ttcgctgctg cgcaatgcag aaacataagc
    10681 gggagcggca aatgtaacca gcttcaaaga atcgctgact gcgccggaca tagccttgta
    10741 ctggtcgaga gaagttgcat tggcagcctt catgtcagcc atgatctttt cggctttctt
    10801 atctttaacg atttcagctc tcaactgatc ctgtacagct ttcagcggac gatatccttc
    10861 cggagtaaca ccaaccagag ctactgcaac catatggtcg ctttcgccac attcatacaa
    10921 accggaaaca tcacccggtt tagcggaaaa tgcccatctc aatgcttctt tagtacctct
    10981 tacaccaccg atagtatgtt ctgagctata caagtctctt ctgtcaagca gtttgtatcc
    11041 ggcttcttca gcgttagcga tcatcttttc agcagtagga ttggcagcga tgaactggct
    11101 gaaatcattg taagcacggt tataagtttc tttgctgaat tcaacttcac gtttcacaac
    11161 agctacttta tatttatcct tcacagcttt cttgttagtc acttgcagga ttacattagc
    11221 ttgtcccaac ggcaggttta ctacttcgtt cacgcctgta ttattgatag cagagataaa
    11281 cttcaggttg tcaccatcga tctgtgcgcc ttcatactgt gcagagctca tccagttagt
    11341 ctcacccgtc tgaccgtatt tcttagccag atctgcgaag ttagcaccgc ctttgatagc
    11401 agtatagata ctgtccgcca aggcttttgt cttcaaagcg tcttctgcaa acacctgaat
    11461 ctgacggaac tcgattgagt cggcagcagc tgtttttgca accactttga atgaattgat
    11521 agtattgtcg gcaccattat agtacggacc ataaacagaa ccaacggatg cagagtccag
    11581 acgggcaact acatctgacg ggaaagctgt tttgttatag aacaagtcta cataa
//
