LOCUS       c00008_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KNEHMEEC_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:29:08
            Original ID  :: gnl|Prokka|KNEHMEEC_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 386913
            Orig. end    :: 411552
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[396913:401552]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             238..1752
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.6; E-value:
                     2.5e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_347"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-81, bitscore:
                     268.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQIELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1767..2009
                     /locus_tag="ctg8_348"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2013..3395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_349"
                     /sec_met_domain="MBOAT (E-value: 9.2e-21, bitscore: 69.2,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRYNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3414..4454
                     /locus_tag="ctg8_350"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFVIGPDYY
                     QKKASREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4559..4951
                     /locus_tag="ctg8_351"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5144..5773)
                     /locus_tag="ctg8_352"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5757..6278)
                     /locus_tag="ctg8_353"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKYGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6299..7090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_354"
                     /sec_met_domain="F420_oxidored (E-value: 6.9e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7087..7419)
                     /locus_tag="ctg8_355"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7422..7919)
                     /locus_tag="ctg8_356"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8125..8667)
                     /locus_tag="ctg8_357"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8785..9768
                     /locus_tag="ctg8_358"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLTAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALRDAHQNGFRHMEF
                     MDVGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_359"
                     /sec_met_domain="Glyoxalase_4 (E-value: 9.3e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_360"
                     /sec_met_domain="CT_Btheta (E-value: 8.8e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_361"
                     /sec_met_domain="OAD_gamma (E-value: 5.5e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_362"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.4e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_363"
                     /sec_met_domain="OAD_beta (E-value: 1.7e-152, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14788..16119
                     /locus_tag="ctg8_364"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16136..17428
                     /locus_tag="ctg8_365"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKSLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17932..19782
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_366"
                     /sec_met_domain="Alpha-amylase (E-value: 2.4e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19940..20380
                     /locus_tag="ctg8_367"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20393..21460
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_368"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 9.5e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLAHLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNAKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21465..23060
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_369"
                     /sec_met_domain="MFS_1 (E-value: 3.4e-13, bitscore: 43.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23155..24159)
                     /locus_tag="ctg8_370"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gtatcaataa agtatcgtgt tgtctatccc attcaaagtc gtcggctatg aagccaacgc
       61 tatttcccct tccgaaagag ggaaagcgag accgggcacg tgcgtaccac acaattaaca
      121 ttctttaatc gattgtacgt agggagatca gaccatttca ctgtcatctt aataaacgat
      181 ctcaagaaga tatataaaga acccctaaac ccaaaacatg aataaaaact aatggatatg
      241 acaacatctt cccagaagga tattatcaat gatattcttt ccgccatgca atgttatccc
      301 gaaaacgaag cattcattat tgacgataaa cattatactt atgcccaact cggtgaaata
      361 acagcttcta tcacccattc gctatcagaa ataaaagatg aaaaaatcgg aatcgtagcg
      421 gaaaaccgga ttgaaaccta tgctgctatt ctggcagtac tagccggcgg aaagacctat
      481 gttatcctgc atcctgccta cccggaagag cgtaatctca aaatagccgc tctggccgga
      541 ctgcgtactt tgctctgtac aagtgacact gaccggtcag cattcggcac cggacacttc
      601 agaatcatcg atacggaccg gctaccggga aaaacactgt cagaacagca gtcccattca
      661 tcggacgaag aaaggaacgc ttatatcatt tttacatcgg gaagcacagg cgagcccaaa
      721 ggagtgccca tcacacgggc taacttgaac gccttttacc gggcatacag ttcgctcgac
      781 tggaatctgg atgaacatga tcgcatgttg caaatgttcg aacttacatt cgatgtatcc
      841 gtagtatctt tactgtatcc tcttacttta ggtgctgccg tttatacggt aggccatcag
      901 gatgtaaagc acttcaaggt gtttgaactt ctggagaagt atcaactgac ctttgccact
      961 gtcactccct cactgctaca actcctttca ccctacttcg acgaaatcaa tctgccctct
     1021 ctgaaatatc tgggagtatc ggcagaagca tcgcaaatcg agctgttgga gcgattcaga
     1081 aaatcggcac ccaacgcaac gttcatcaac ctatacggac cgaccgaagc tacgatttac
     1141 tgcacctgtt accgtattcc ggcttcggac aaatgcaagc attacaacgg aatggtggct
     1201 atcggaaaac catttcccgg catccgcgcc atcattgccg acgaagaagg aaacgagcta
     1261 cctcaaggag agacgggaga actttgggta tccggccggc aggtaatgaa aggttatctg
     1321 gacgacccgg aaaaatcggc attggttctg atacaccgtc ccgacggaca aatctattac
     1381 cggaccggag acttgtgtat tctggatggc gacggggata ttatttattg cggacgtaaa
     1441 gactatcagg tgaaaataca gggtttcagg atagaactga gtgaaataga atatactgcc
     1501 cagtcgtttt tcaagactcc ctgcagcgtg gctgccgttc cgttgctctg cgacggaatc
     1561 tgtaacgaat tgcacctggc cgtcgagaca actgaatgta ctcaaagcgc attgatagaa
     1621 tatctgaaag aaaagctgcc caaatacatg ctgccgaagc agattcattg tatttcccaa
     1681 tttccggtga ccaatagtaa taaaacagac cgtaaaaaga ttgccgaact gataaaagag
     1741 aagaaactct aaaaacaata ataaatatga atcgagaaga agtattaaaa caactacaaa
     1801 gcattttccg tgatatctta aaaaaggaca acgtatgtat cgacgaatca tctacctcaa
     1861 aagatgtaga tggctgggac tcgctaaccc acatgcaaat tatagctcaa atcgagaaac
     1921 atttcggagt acgtttcaat ttcagggagg tcattaagtt caagaatgtc ggcgatttgt
     1981 gcagtgcctt attaaccaaa atggaataaa cgatgcagtt cctctctttt agtttcctgg
     2041 ccctgtttac cctctgtttc ttcctctact atgcagtcaa aggccgtgcc cgcaacctca
     2101 tactactggt aaccagttgt attttcatcg gatggtacta tctgcctttc ctgttgacgg
     2161 cagtagtggt agcactgttc accttctttt gggcacaatg gatggaaagc agggcaaaag
     2221 ccggaaaaaa gaccaaaccc gtctatatcg caggaatcat cgccctgatc ggcggatggc
     2281 tccttcttca tggcacggtc atagatgata tcatctttcc acttgggatg tcattttaca
     2341 catttcaagc catcagttat ctgacagacg tgtactggca agagcaacgc agcgaaagaa
     2401 actgggtgga tttcctgatc tatatgcttt tcttcatgaa gtttctctcc ggccctatcg
     2461 aacggggtgg agacctgttg ccacaattga aagatccccg cccgttcatc tactcaaacg
     2521 cggtgaccgg actgaaatat attttactcg gactgatcaa gaaactgctg atagccaatc
     2581 agatctcccc acaaacagat gtcatgtttc attcgattca tgacctctcg ggtgtacaac
     2641 tgctaatgac ttgcctactc taccctatcg aactgtatgc cgatttttcg ggttatacgg
     2701 atattgctat cggaggggcc tatatgttcg gcatcaagtt gtctcctaac ttcaaccgcc
     2761 cgtttgcagc acgctcgact gccgacttct ggcgccgttg gcacatgtca ctctccttct
     2821 gggtacgcga ttatctctat gtaccgctaa ccgccggtac ccgtaactgg ggacagtggg
     2881 gaatctactt cagcctcctc atcacctttc tcgcattggg tttgtggcat ggggccggat
     2941 tgactttcgc catatacggc ctgattcagg gtgtccttat ctgctgggaa atgaaaacag
     3001 ctgctttccg ctataatctg ccccaatata taggaaaata tgcggccgac agcttgctga
     3061 ttgtccggac ttatctattg ttcgcactct cgcttatatt ctttcgtgta caatcgctga
     3121 gcgatgcctg gtatttctta cggaacatct cgttcgaggt acattcttcc tggaaagaaa
     3181 tgaacatcgg catacgcgat cataattgca tcgtagcagg ttcggcccta ttactagtat
     3241 tgatctacga atattatgca tctaagtaca acctgatgga aacacttgaa cgccaacccg
     3301 catggttacg gtggagtgtc tactatctgt tggtattcgc tctgctgatg ttaggcaaat
     3361 ttgacacgga aactttcatc tatttacaat tttaaccgaa accctttacg cgcatgctac
     3421 atcattcatc gagaatctcc cccaagacac gtttttgcct gaagttgctt ttactgatcc
     3481 tgccgctgat cccgatagtg gttgtctatt ttatgtttga tccttatagg gtattacacc
     3541 cctacaaacg attcgacgac tctcccatgc tactcaacga agcccatgtg ggatggcaga
     3601 attatctgca gaatcgcgat tcgatagcct ataactcctt tatactcggc aactcctgta
     3661 ccatggcatt cctgacagga gaatgggaaa aatacctgga taagaacgac catgccgtac
     3721 gcttctatga caacggagaa agcctgggcg gcgtccgtca aaagcttcag ctgctcgact
     3781 ctgtaggtgc acccctgaaa aatatactga tcgttctgga taaaaaatca ctggacaaaa
     3841 acgctccttt atcgggcaac aatcatctgt tttcggccga agcagccggc atcagccaat
     3901 tgggattcca gttgagattc ctgcaggagt tcctttatcc ggacagaatg attccttaca
     3961 tagattatct gatccgacat aagtatgctc cttatatgaa aggggttata aatccgggag
     4021 atcccgtcag ggagccttac acgaacaatt ttatcaatcc cagagaaaaa gagatcgcgc
     4081 aagatggcga aatatactgg agccgtcatg aaaaagaatt caagaagcga acgaatgcgg
     4141 gtatggaaga acttcctgtt atatttgcca gccagattca ggtacttcgc tccatcaaaa
     4201 aaatctgcga taagcaccac acgaacctga agttcgtcat cggtccggat tactatcaga
     4261 aaaaagccag ccgggaagat ataaaaatat tgaaggctat actgggtgat tccgctgtct
     4321 gggatttcac gggaatcaac gaatacacag ccgacataca tcattattac gaacccggtc
     4381 attatcgtcc gctgctggga gcacgcttac tgaaagccat ttatcaggat caagacacct
     4441 gccacaggca ataaaagttc ctcccataac agtagcacac acagaagaag agcatcctcg
     4501 atccgaaaga aataattata tcaaagaaaa caattatatc acattaaaaa cttagattat
     4561 gaaaaagatt ttattattgc tatccgtctg tatttcattt tcatcatgct gtacattatt
     4621 cagcagttcc aaacaagata tcacctttac gggaatgaat ggaaccaaaa tctacgaagc
     4681 atcgaccaaa cagaaaatag cggaaatcaa agaagacaat agtgtcactg tacaaatcaa
     4741 aaagaaaagg gaagacaaac aactagtagc caaaaaggaa gggtaccaaa cgactccctt
     4801 tgtcctggaa tctacattta acaatgcctg cctgtggaac attctatttt ggccgggctt
     4861 tctggtagat ttgggtacgc aaaagatgaa caaatgggat aacacaatta tcaatatcga
     4921 aatggagaaa gaaaatacag aaaacaaatg atcaaactat aatttcgcat ggcactcttc
     4981 tccttccacg gagggagtcg ccatacggaa tcatgcgacc tacaaggaag gcataattca
     5041 ccacaagtca acacagagtt ttttataaaa gttctttaga gaataaatct actctgtgag
     5101 actctgtgct actccgttgt atatacgagt ttcggcacac tctctatagt tgtttcaatt
     5161 ccctgtataa tttctgaatg ggaagtccca ttacattgaa gtagctgccg gatatggatt
     5221 ctactccgac aaaaccgatc cactcctgca caccatacga accggctttg tccatgggct
     5281 gatagtgatc gacataataa gcgatttcat cttcatcaag aatcgcaaaa cggacatccg
     5341 tcacggcagc gaaacatttt tgccattctc gggtagtgag acacacaccg gtaatcactt
     5401 ggtgcgattt accggagagg ctccgcaaca tctctatggc atcctgcctt ccaacaggtt
     5461 tgccgagcgc tttgccttca tgccagacaa tggtatcggc tgtgatcaaa agctcttccg
     5521 gtccgatcat cgactgatag gcggctgcct tctcacgggc tatgaaaaga ggaatctctt
     5581 caccttgcaa cgtatcggga taagattcgt ccacatccgg caaagttttt actacataat
     5641 cgacacccaa gcccgtcatc agttctttgc gacgcggaga attagaggcc aatacgattt
     5701 tataacgatc taagttagca agcatactga taaataaata aggtatatac tggaaatcac
     5761 catccgaaag catcatcgga caaccattgg ccttgtgctt taagcacctg ctccaccaca
     5821 tcgcgtccac agccgtatcc tccatcggca tacgaaatgt aacgggcaat cgctttcacc
     5881 tcgggaaccg catctttggg acagcagggc aatccgcact cacgcatcac ttccatatcg
     5941 ggaacgtcat cgcccatgta gagtatctcc tcgtccgtaa gtccgtattt gtcacggaaa
     6001 ccacgataat cgtgtatctt caccgcagag ccgaagtaca gatcggatac ccccaaccct
     6061 ataaaacgtt tccgcacgac atcgctccgc ccacctgtaa taatagcgat acgaagccct
     6121 ttttttacgg ccaattggat ggcataaccg tcttttacat ttaccgtacg catcggttca
     6181 cccgacggat gcaaagggat gacattggcg ctcagcactc cgtctacatc gaaagcaagt
     6241 gcctttatcc gggtaaggtc gtaattgatt gtgctcattt ttatttaatg tttcgggatt
     6301 attgtctttc gtgaatgctt cggctaagca actcgtataa ccgctgcatg gcaggatcat
     6361 cggcaagcat ccgcaagtga ttgccgatca cattctcgtc ataacggatg gccggcccgg
     6421 tctgggccgt cttaggttcc agttcgtgca ccttacgggc ggtttcatca atcaacggca
     6481 acatcacgtc aaacggcaga ttgtatttct taagcaactc ggcagcaagg gcatacatgt
     6541 gattggtgaa gttacatgta aacacggcag ccagatggag acttttacgc tgctccgagt
     6601 cggcatcgta cacacggttg gacagtgtag aggcaatggc tttcagaaac gcggcatctt
     6661 ctgccgaaga agcctctatg aagaaaggaa tctccttaaa atctacctcc cgctgcttgc
     6721 tgaaagtctg catgggatag aacacaccgt aatgcgagac atgtccttcc cagacattca
     6781 tcgggatgct acctgccgta tgcaccatca atgcctcttc ccgcttacct tcgacaatgc
     6841 cctgaagaag ttcggcaaag gcggaatctt tcagtgaaac aatatacagc ttcgcatacg
     6901 ggttcacctc tgcgaggtct gtcgtatatt cggcttccac tttctgtgcc agctcgcggg
     6961 ccgactcttc cgtacggcta tacacctgta cgatacgaaa acctttccga tataaggctt
     7021 ttgccagatt agtggcaaga tttccggcac cgataaatac gatcggcgta tcttctatac
     7081 ttcttttcat cgtgttgaaa tcaaatacaa tatacctccg attatcaata aagccaaagg
     7141 cagcagataa ccggacatcg aaccaagcaa cgaaacaatc aggccgatgt tcagcaccaa
     7201 ccacaatccg agcaatacca agccgacgga tttatcccgc ttaataaaca ggaaaatcac
     7261 cgcagtgtaa agcaaaagat tatccttatt catcacccag ggtatcccca aagtggaaaa
     7321 gtgtatcagt ttgtcgatca gatagagcac ccccatcaca ataagggtga ctgctgtggc
     7381 tttgtaggta tctttattgt ttgcttttac cgcactcacc gttacttacc tccgaactta
     7441 ttaatatgga ttttttccca ttgcaaatgg tcttcattaa agggtttacg ttccatccct
     7501 ttatgcccga tcgctatgac ggacaacacc tgcaactgca aaggaatgtc gagcacaccg
     7561 cgcacaaatt catcggaagg catcccggtg gcagtatatc gctcacgcac ctgcacccag
     7621 caacttccca atcccaagtc ttcggcctga agctgaatca taatagaggc aatggaagcg
     7681 tcctcaatcc atacatcgct cgccaaggga tcggcagtaa cgacaatggc caatgccgcg
     7741 tcggcaataa aggccgaagc ctgctctttg caatgtgaaa gttcactgag caacttttta
     7801 tcatcgactg caataaattg ccagctgtta ctgcgctttg aagtaggagc catcagggcc
     7861 gctttcagca aagcgactac atcttcctga gaaagttctt ctccggtaaa tttccgcatg
     7921 ctgcggcgat tttttattag ttcactgaaa ttttccatgt atctatactt tgcattattt
     7981 gaatataccg ccagtcacca tagaatgcac aaacacacgc gaaccgaggt accgcccggc
     8041 atgcccgtct atataaggta tgccctgcag gactttgcat gaatcggcgc gctccgtggc
     8101 gattcgagcg caaagatagg caatttattc cactctcgtc aactcgccgg tcagtgaatc
     8161 gatgataaaa ccatgcaccc ggacatcttt cggaataagc ggatggttct ctatggaacg
     8221 aaccgtgccc ctgacggact tcaccggatc gtcgaatccg cccagccacg aattaaaatc
     8281 gaccccgcag tagcgtatca tgtcgattgt ttcggacttg attccccgct ttttcatgtg
     8341 agctatcatt tcgtcgctgt tcatgtggca agcaccgcaa tcagaatggg caatgaccat
     8401 cacttcttct actcccaact cgatgatagc caccagcaga ctacggatga cactgccgaa
     8461 aggatgggaa atgacggcac cggcattctt tataatcttt acgtctccgt tgtgaatccc
     8521 caaagcggcg ggcaacagtt ctgtcaggcg ggtatccata caggaaagga tggcgatttt
     8581 cttatcagga tacttgttag tgatatactt ttcgtatccc ctgttctcaa cgaacttttt
     8641 gttgaattca agaatttctt ctaacataat caaaaacgga ttttattgta gtatctccac
     8701 aaagatagtc acaaaacgac agctcaacaa aataagccct gcaaatgttg taaagagaaa
     8761 taaaaaatgt aaatttgtcc cgatatgcca ttaaaactga ctacatatta ccaaggaagt
     8821 gagattccgg attttcccgg aaccaatacg tttcattcga aagagctatt tcagatctac
     8881 gaagaaactc cgggctacac cccgcttctg attatggctt cggaagacgg aaaacctgtt
     8941 gcgcgactgc ttgctgccat ccgcaaaagc atccgcatgt ttcctcccgc tttcatcaaa
     9001 cgctgcgaaa tctatggcac gggcgaatat ctgacagcgg aagccgacaa ggaaaggata
     9061 ttcggcgaaa tgctggagca cctcaccacg gaggctttgc ggaactcgtt tctgatagaa
     9121 tttcgcaatc tggagaacgc catgttcggc tacaaatatt tccggtccaa cagatacttc
     9181 cctgtcaact ggctgcgggt acgaaactcg cttcacggca tcgaaaacgc cgaacagcgt
     9241 ttcagcccct cccgtatccg ccagatcaaa aaaggcctga aaaacggagc aaaagtagac
     9301 gaggcacgta cggtagaaga gatacgcgaa ttttcgaata tgctgaggca tctctattcg
     9361 tcccgcatcc gtaaacattt tcccaacatc atctttttcc agcacatgga cacccgactg
     9421 attcacagcc ggcaggcaaa gattttcatc gtccgctaca aagacaaaat tatcggaggc
     9481 tctgcctgta tctattcggg aaacgatgcc tatctctggt tttcgggagg tatgcggaag
     9541 acctatgcct tgcaataccc gggtatactg gctgtatgga aagccctccg ggatgcccat
     9601 caaaacggat tccgccacat ggagttcatg gacgtcggac tcccatttaa gaagcacggc
     9661 tatcgtgact tcgtgctccg cttcggtggc aagcaaagca gcacccggcg atggttccgt
     9721 ttccgctggc aatggctgaa cgacctgctg atcaaaatat acgtctgaac atccgcctgt
     9781 ctcagggatc agcgccaacc ctctccgtct tttaaaccac cccccttagg ttttaaacca
     9841 acgatgcctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccaggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaagt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccatacaatg cagccaaata cggttacatt gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagcggtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgcccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgct gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaatc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat cggtaatgca ggtgtatctg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt ttcattagta aggtagacgt tcttcttttc gcaaagaagg gcgtcttttt
    14701 tttgcgttaa tctatctaaa agatattacg aatctttcgt agaatggata tttttactaa
    14761 cttgcggaca ataaaacaat acgtcctatg agaacaagaa caatgaaacc actcttcctt
    14821 attttctgtc tttgcctcag tcccctactg atgggccaga atcaaaacaa aattcaggaa
    14881 gcaatggcaa actatgacta cgagactgcc gttgaactga taaacaagga acctcccacc
    14941 atcccactgt taatgcagaa agcaaaagcc ctgaaaggaa tcggcagcaa tgcggaagct
    15001 ctacgttcca tccgccaagt gatagcggaa gactccacca accaacaggc acacatcgaa
    15061 gcagcggaat gctgtaaagc aatggccaag tacaacgatg cgctggacta ctaccggaaa
    15121 gccatcagcc tgaatcccaa aaacaagtat gcccgtttgc aattcatcaa cctgctttgc
    15181 aacaccaaaa actatgctga ggcttttgga gaaagttcaa tgatgtccga aacggacagt
    15241 tcggccgtag tgctccacct acaggctcaa agccttgaag ggatgcaaca gatactaccg
    15301 gctatcggtt gctatgaagt cattcaggat aaatatccgg acgattatct ggctgcggcc
    15361 aaactcggaa acctgaacat tgtggctgga tatcccgaat atgccatcca agctaccgaa
    15421 cgctataggg aacgggactc caccaacctg attgtcaacc agcaaaacgc tctcgcctac
    15481 tgccacgccg aacaatatcc gacagccatc aagcgctatg aaaagctgtg ccaacagggg
    15541 gacagcagta cacagacctt atactacctg ggagtcagct attacgcgga tgaatattat
    15601 tacgaagcgc acgcgtgttt cagcaaactg caaaaagaga tggaagaaaa tcccaatctg
    15661 ctctattatc tgggacgttg ctgcgccaag acttcctgga aaaaagaagg catcgaacac
    15721 ctggagaaag ctatcgaact gaccattccc aaagacagca ccatgatccg actttacaaa
    15781 ggcttggtgg attgttgtaa actggctcag gatactccaa agcaaatcca ggctctcaga
    15841 gaactgtaca aatatgacaa gacgaaccat aaacttcttt atgacatcgc ctggaactat
    15901 tcatatcaac tcaaagacaa caaatcggcc gaacgttatc tgcaggcttt cttaaaaacc
    15961 cgaaaggcga atgccaggaa agaagaaccg gtgagtgaga aaggggaact tgtactcgga
    16021 cttgaaaatt attacaacgc tgccgaaaat tggctgaaag acttacagaa agaaaagttc
    16081 ttcaaagaag gaataccgtt agaaagtcag aaacaataga atctgtcccc cccccatgaa
    16141 acattggata ctcctcctct atctggggtt cagcgtagtg ctgcaagccc agaacaccgc
    16201 ctccgttcaa gaagcaatgg caaactatga ctataaaacg gtgatcagac tgattgatga
    16261 agaaagtgca tcaccacagt tactcataca gaaagccaaa gctttaaaaa gtttagggcg
    16321 taccgccgaa gccctgtcca ctttgcaaca tatcattatc gagctgcccg aaaatcagca
    16381 ggcattggta gaggcagcag aatgttgcag gcaattgagc aaatttaacg aggccttggg
    16441 gtattatcgg aaggtgatgg aactcaatcc cgaacatatt tacgcacact tgcaatacac
    16501 ccgcttgtta tacaactatc agcgatacgg cgatgcattg cgtgagagta tcgcattggc
    16561 caggaaagac agttccgcca ccgtattgcg actgatggcg gaaagcatgg aaggagccgg
    16621 catgccggta gaaagtatgt tttgctatct ttccatcatc aggaaatatc cctccgacta
    16681 tctctcggta gctaagctgg gcagtatctt caatacaatg aaagattacg aaggggcaat
    16741 tgccctgaca gaagcatacc gccggacgga cagcaccaat gtagaagtga accgtcaaaa
    16801 cgcactggcg tattgtctgc gcaaagaata tcccaccgcc atcaaacgtt atcaggatct
    16861 gaccgcccgg ggagacagca cactgctgac atgttattac ctgggagtca gctactacgc
    16921 tacgaaagaa tactataaag cgcgcgattg gctactcaaa gcaaaatcat gccagtcacc
    16981 cggcgccaac ctactctact atttgggacg ttcgtgctcc aagacattat ggaaacaaga
    17041 gggaatagga tatctgaacc aggctatcgc cctgactatc cccgccgaca gtatcatgga
    17101 gcgcttatac tcaggcttgg cagactgcta caggcaaacc aagcaaaccc gggaccaaat
    17161 caaggctacc aaagaacaat acaaatatgc ccctgacaag catattttac tttataactt
    17221 ggcgttctta tcggacaaaa taggagatac taaagccaca gagcattact tgcaggcttt
    17281 tctgcgaaca aaatccaaac aaaatgcagt actacagcag ccggatgatg acgaagaaga
    17341 acccgcaccc tacatagatt actacaaaag tgccaccaat aaattggaaa gcatccgaaa
    17401 agagaaattc ttaaagggag aaaagtgaat tgatcggata gatgcatcgt ttcggacaat
    17461 tcaccactga gtgcagacag agtttcacag agggagaata atggaaaata aatttgaaga
    17521 tgtgcggtag aaggcacagt ggcacgtaac cgaagtcaca tcggcacgca gccgaaatta
    17581 cggtgctgtg tagctaaagt tacggtgctg cgtagccaaa gttacggtgc tgcgtagcca
    17641 aagttacggt gctgcgtagc cgaagttacg gtgctgcgta gataaagtta cggtgctgcg
    17701 tagccgaagt tacggtgctg cgtagccgaa gctatgacgg catctccttt tccggacgtc
    17761 acgttcacct gattgcatcg aaaagtgttc cttatcggtt gagctccatc ccggagaatt
    17821 ctccaatgaa aacgtttgca taaatagatg gcacacagta agaaagaaaa cggaaaacaa
    17881 tccgatgatt taccctatat tagcaacatt aaataataac gagctaatat catgaaaaaa
    17941 ttattgttac tcttaggttc attcctactg tcattaacca cttatgcagc catgaacata
    18001 tccaaaatcg atccgccctt ctggttcacc ggtatgaaca atccggaact ccagttaatg
    18061 gtatacggtg aaggcatcgg ccaggcatcc gtatcagtaa attatcccgg tgtatcgctc
    18121 agcagcgtcg tgaaactgga aagcaacaat tacctgcttg tctacctaca tctcgataaa
    18181 gaagtaaagc cgggcaagat gcccatcaca tttacggtcg gaaagaagaa attggtgaaa
    18241 gagtacgaat tgaaagcacg cagcaaagcc ggagtcgatc acaaaggttt tgacgcatcg
    18301 gatgcattat acctgctgat gccggaccgt tttgccaatg gcaatccgga taacgaccgg
    18361 atagaaggca tggccgaata taaagtggac cgcaacgacc cgaacgcacg tcacggaggc
    18421 gacctggccg gtatcgaaca aaatctggac tattttaccg acttgggagt gaccgcactc
    18481 tggttcaccc cggtactcga aaataatatg aaaggcggct catatcacgg atatgcaaca
    18541 accgattatt acaaggtaga cccacgtttc ggcactaacg aggaatatcg ctcactgata
    18601 gcgaaagccc acaaccgggg catcaaggtc gtgatggaca tgatcttcaa tcattgcgga
    18661 gtagaacatc cctggatcaa ggacatgcct tcaaaggact ggttcaacca tgcggacttc
    18721 aagaacaact ttgtgcaaac ttcctacaag ctgactccac atgtagatcc gtatgcctcg
    18781 gagtacgatt tcgaccagat gaacaacggc tggttcgtgg aagccatgcc tgacctcaac
    18841 caaaagaacc ctcacgtata caaatacctc ttgcagaaca gcctgtggtg gattgagtac
    18901 gccgatatcg acggcatccg gatggacacc tacccgtatg ccgattacga tgccatgagc
    18961 aactggatga aagaactgaa cgaagaatac cccaactaca acacggtggg cgaaacctgg
    19021 gttaccgaac cggcctatac agcctggtgg cagaaagact ccaaactctc cgccccgcgc
    19081 aacagtcact tgaaaacagt catggatttc agcttcttcg acaaagtcaa cacggccaag
    19141 aatgaacaaa cggacacttg gttcaaagga ttggaccgtg tctacaacaa ttttgtatac
    19201 gattatctgt atcccaatcc ggcttccgta ctggctttca tcgagaatca tgacaccgac
    19261 cgtttcttgg gtgaaggcga aaacctcgat atgctgaaac aggcctccac ccttttattg
    19321 accacccgac gcatcccgca actctattat ggaacggagg tgatgatgaa cggagtaaag
    19381 agtaaaagcg acggctatgt acgaaaggac ttcccgggcg gatggacgga cgataaagag
    19441 aatgccctga ctcccgaggg acgtacccga ttgcagaatg aaagctataa cttctaccgc
    19501 aacctgctga actggcgtaa gggcaacgat gtgatcgcca aaggcagcat gaaacagttc
    19561 atggtgcagc acggcgtata tgcttatgca cgccaatata aagggaaaac ggtattcgtc
    19621 ctgttgaacg gtacggataa agaggtgaaa cttcccctga aatactatgc cgaagtgctg
    19681 aaagacaaga ctcaaggaaa agacgtcatt agcggaaaag taacggcact caatgaagaa
    19741 ctgacaatgg caccccgcca atcgatggtt atagagcttt aatctcacac cggttataac
    19801 cgcataagca aagggcacaa aggatttcac ccgacatcct ctgtgccctt tgtgtagcct
    19861 aatgcgaata ataatagtca aacgtttgac tattatcgga gaatattcct acctttgcag
    19921 cgactaaaag aatacgacga tgacaaacaa cgaatcggag cgcgagctcg tcctacaaac
    19981 cttacgaacc tggatggcat tccgccaggc cgttcagcgg gtactcaaac gccacaacgt
    20041 ggatatgacc ttcgagatgc tgcaagtaat gaactgcctg tggaacaaac aaggcatcag
    20101 ccagcaatcc ctggctgaga aaacagcaaa ggacaaggct tgcctgacca atctgattaa
    20161 taatctggaa aagaaaaact gggtgatacg gaaagaaggc ccctccgacc gccgaaaccg
    20221 cctgattttc ctgacgcccc aaggcgaaga acttgccctc accgtgaaac ccctgatcaa
    20281 cgatatctat gcccaaaccg gagcagagat ggaggcaagc cggataacgg aatgcatcga
    20341 agacctgaag agactgcatg aagtgctcaa tgagatctaa aagaaatccg ccatgtccac
    20401 ccgtcagata aagctaaaac aattgagaag actgaagttc aggaacatct ttctcaacac
    20461 agtatgcatc ctgctggcat tggcaggtat ttcatggaca gtaaactact tctggaaata
    20521 cgcccgctac gagataacca atgatgccgt agtggatcaa tacatcgctc cgctaaacat
    20581 ccggataccg ggctatatca aagaagtacg ttttaccgaa catcagtatg ttcatgccgg
    20641 cgacacgtta ctgatactgg acgaccggga ataccggatc cggctgaaag acgcggaagc
    20701 ggccttgatg gatgccttgg gatcaaagga agtgttaaac tccggcatcc ggacttcagg
    20761 agtaaatgta gccgtgcagg aagccaacat agccgaaaca ctggcacacc tttcacagca
    20821 agaagcggaa ctgaaccgat atacccggct cctgaaaaag caggccgtca gccaacagga
    20881 ttatgaactg gccaaagcga acttcgaagc gacccgggca agatacaacg ccctgttgcg
    20941 acaaaaagaa gcggcccaat cgcagtattc cgaaaccagc aaacgcagta caggcgccga
    21001 agccaatatc ctccggaagg aggccgacct ggagatggcc cgactaaacc tgtcgtatac
    21061 cgttgtcacc gcaccctatg acggatacac gggacgacgt acacttgaac cgggacagtt
    21121 cgtacaaggc ggacaaactc tttcctacct ggtacggggc aatgccaagt gggtgacagc
    21181 caattataaa gagactcaaa ttgcccatat ctatatcggg caaaaagtcc gcatcaaagt
    21241 agatgctttc agcggacgca cttttcacgg gaccgtaacc gccatttccg aagccaccgg
    21301 atcgaaatac tccctggtac cgaccgacaa ttcggcaggg aacttcgtca aagtgcagca
    21361 acgcattccg gtccgcatcg atctcaatga cgcctcaccc gaagagatgg aatgtctccg
    21421 tgcagggatg atggtagaaa cggaagcggt ccgcccttag gcttatggtg aagctcaatc
    21481 tgcctacccg tccctgggtg cctcaatggt tgggcatcgt gaccatgttt attgtcatct
    21541 ttcccatcac cctgctcaac ggtgcctaca caggaagtat ggtcgaagta tcgaacacgc
    21601 tgggagtatt gagcgaagat attaccatgg cttactattc agcttcggta gggatggctg
    21661 ttgcctatcc catcgtaccg aaaatacgca ccatagccac tccgaaaacc ttactgctta
    21721 ccgacctgct gctacagata ttcttcagcc tggtatgcgc caaaaccggt agtatggatg
    21781 tcatcatggt atgcagtttc tgtatgggat ttctcaaagc cttcgtcatg ttggagttca
    21841 tcatcctgat ccgcccgctc ttcagtccga aaaacgtacg aagtgaattc tatgcctact
    21901 tctaccccat cgttttctcc ggaggtcagc tatcgatggc tatcaccgct caactggcct
    21961 atcactacca atggcagcac atgtactatt ttgtcaccat cctcttgctg atcgccattc
    22021 tgttcgtcat ctgtttcttc cgctatgcaa ggcgtcccat gcacattccg ttcaaagaaa
    22081 tggacggaag aagcatgttc atcatcgcca ccgctttcct gctaacgctc tatacattta
    22141 cctacgggaa aacactcgat tggttcgcat ccccgaagat cagagtatat gtattcgtca
    22201 tcccgctcct gatagctctt ttcatccatc ggcagcgtac acaaggcaaa ccctttgtca
    22261 gcctgaaacc actctttctg cataaatcca tcatcggata tggcttcatg gtactcgcca
    22321 tgttcctgac agccaccagt tcactggtaa ccaactatat gaacagcatc atccgggtag
    22381 acagcataca cgccaattcg ctgagcctgt ggctattgcc cggatatgtg gtaggggccg
    22441 tcatttgctt ctggtggttc cgatggcaac gatggcggtt tcgcttcctc atttcaggag
    22501 gtatgttctg ctacgtcatc tatctggcta tcctctactt tggtatcacc ccttatggaa
    22561 cttatgaaat gctctacctc cccatcctgt tccggggagt ggggatgatg gtcatattca
    22621 ttgcgttcgg tgtgtttgtt gtcgaagatt tagacccgcg cctgacgttg tccaatgcct
    22681 tcttcctgat ttcattccgc tcagtattag ctccggtcct gtccgcttcg ttctttaaca
    22741 acatgcttta ctatctgcag gcaaagggga tgaacattct ttcggaaaac atgacgctga
    22801 ccaatccgct ggccgaacaa aaatacaatc aggcattgag caatgccctg gcgcaagggc
    22861 acgaattcgg cgaggccgga caattggcag ccaacagtct gtactccact ttgcagcagc
    22921 aatccctgtt gcttgccctg aaaaccctaa tcggctatgt actgatactg gcactggtga
    22981 ttgctgtcat cgcagcgttc attcctttcc ataaaacgct gaaggtggct gtagtgaaga
    23041 cgggtgacga tatggtataa tgagaaggga tacaaaaaag ccacccaatt gcttgagtgg
    23101 cttcttaaaa tataaattaa atcaagtaaa acttttaaat actagatttg gaatttattc
    23161 agctaacttg ttgtcagaac ccagcacgtt gataattttg tgcttgtaga gtttttccat
    23221 attgtcgcga gccggtccca gatatttacg cgggtcgaac tcagccggtt tttctgcgaa
    23281 taccttacgg atagcagcag tcatagccag gcgagagtct gagtcgatgt tgattttgca
    23341 aacagcagac ttagcggctt tacgcagttc ctcttcagga ataccgatag cagctttcag
    23401 tgcaccacca aactggttga tagttgcaac ctcttcttca ggaactgaag atgatccgtg
    23461 aagaacgata gggaatcccg gaagttcttt cattacaccg tccaatacgt cgaatgccaa
    23521 cggaggagga accatacggc ctgtcttcgg atcgatgtgg cactgttccg gagtaaattt
    23581 gtaagcaccg tgagaagtac cgatagagat agccaatgaa tcgcaacctg tcttggtaac
    23641 gaaatcaact acttcgtccg gttcagtata tgtgtggtgg tcagaagaaa cttcgtcttc
    23701 tacacctgcc aatacgccaa gttcaccttc tacagttaca tcgaactggt gagcgtattc
    23761 aacaactttc ttagtcagag caacgttttc gtcgtaagga aggtgagaac cgtcgatcat
    23821 tacagaagag aagcctgagt cgatacagct tttgcaagtt tcgaaagtat ctccgtggtc
    23881 gaggtgcaaa acgatttcag gatttttgca gccgagttct tttgcatatt ctacagcacc
    23941 ctgagccatg taacgcaaca atgtagcgtt agcatactga cgagcacctt ttgatacctg
    24001 caaaataacc ggagacttag tttctacagc agccttgatg atagcctgca tctgttccat
    24061 attgttgaag ttgaatgcag ggattgcata tccacccttg atagccttag caaacatatc
    24121 tctagtgttt accagaccta aatctttgta attaaccatt ttgtttaaaa gtttattgtt
    24181 agtgaattaa aaattctatg caaaagtaag aataatcctt tgaatagaga aaccctcggg
    24241 cggaaatatc cgtttgagga gcgtaattca attctatttc aaattatttc ccatccttta
    24301 agagctgttt gtaatgtcta cgtagcaaat aaaggttttt tattgtttcc tcatatatat
    24361 aatggtaggc aaatgatcgc tgtaaccatc caaccacact ctgccaccat atgtacgcag
    24421 gggtgcaccc ttatatttac catcctgctg aaacaggtaa tcgcgcatga aaacttcatt
    24481 gtgatcatat ttcaatcctt ttgtggcttg aagcagcgtg ggcgaaagga tgatctgatc
    24541 gaacagattc catttgccgc gatagagcaa agtgcccact cccttatctt ccagcgtcac
    24601 ccaccagggg ttgtaaaggt catcttcagt catatcttc
//
