LOCUS       gnlProkkaMDAFDENC_49   16621 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDAFDENC_49.
ACCESSION   gnlProkkaMDAFDENC_49
VERSION     gnlProkkaMDAFDENC_49
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:09:29
            Original ID  :: gnl|Prokka|MDAFDENC_49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16621
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16621
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1142:6621]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1143..6621
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..16621
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16621
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(29..301)
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="MSNQVPYNLFSKWYKDTRKKIIPVLVLGAPSTESEMPESPSPLPE
                     QKSESDPRLFCHTELRILVDIRMSNGVHISQKNLSNEGKQSKIGS"
     CDS             complement(491..1156)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 117.9; E-value: 8e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MMSDKQTIKAVLFDLDGTLLNTSEGIACSVLHTLSVMQLPSISSD
                     EVSTFIGPPIQESLKRHFRLSDEDVQKGADIFRAYYKDCALFKAALYPGIIDLLKQLKQ
                     KGFLIGVATYKREDYAMDILKHFGILEYCDVVHGADNDNKLRKSDIVYLCISEMSVDNS
                     EVVLVGDTYHDLEGAEEADIHFIAVTYGFGFRESVRELSSKNVVGVADNPMEIEGLLK"
     CDS             complement(1143..2747)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 58.9; E-value:
                     7.9e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="HMGL-like (E-value: 3.4e-21, bitscore:
                     69.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKVLMLDCTLRDGGYVNDWDFGHSTITGIYKRLEAAGADYIEV
                     GFLDDRREFDINRSIMPSTEAINKIFGSVKKGKAIPVAMIDFGTCSLDSIGSCDSTFID
                     GIRVIFKKEKIDQALPFCKAIKEKGYKLFIQAISITAYSDIEMLEYVNRINEIKPYAFS
                     IVDTYGLLDNSSMARYFYLIDNNLDPSIKMGYHEHNNFQLGFSNTIKFLEKSTKRTLVA
                     DSTVYGMGKSAGNCASELLAMHLNEYYGGHYDLNQLLEIVDTDLMPIYQKHYWGYKYDF
                     YIASMQRCHPSYVQYLLKKSTLSVSSINEILSSIPEEIKLLYNKQWIEQAYLDYQNRAK
                     DDTEALQQLKVELEAASDKPVLIIGPGNTVKEQKKGVELFISGNDPVVFSVNFYTKLYS
                     IDYTFISNAKRYAKFVDIQHGDSIGSKLILTSNVTACDYMPNYVLNYESLLNKESENPD
                     NALVLLLKALIRIGITEVYLAGFDGFTNTPNDYYDRDYELSSTKDESYNDLLSDDLSKI
                     NQSIRLHFITESLYDVR"
     CDS             complement(2751..3488)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-12, bitscore:
                     41.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIIAIIPARYQSSRFPGKPLADIFGRPMIWWVYNQVIKVKEFL
                     EVYVATDDQRIADVCSNYGMKFIMTQSNHPTHVHRIHEVSDNIAADYYVVVCGDEPLIG
                     PDIIEAVFPSQDVDNSHMYVGGLCRYFTEPAEVIDPANIKIVTNDSDECVLLSRAPIPF
                     PYKTVLFKYKKVVGVECYNKQALDFFVSTPKGYLENIEDVTLQRFLENKIHIKYKLVDS
                     VSLSVDTPRDLEKVKEIMVTKQA"
     CDS             complement(3551..4234)
                     /locus_tag="ctg49_5"
                     /transl_table=11
                     /translation="MKITAVIPIRSGSQRVKDKNLRAFADTNLMELKIKNLLQVPELTS
                     IVVNTNSELAIEIVNKSYRGGVTTHRREEYYASSQCSGSEFFRHLGEVTDTDLFVYCPC
                     TSPFIKPETVSQCINQFISTSDYDCLATVSSVKEFLWLDGDPMNYDPAHAPNSQDLPDV
                     VALNFGVTVVRKEDLIKNSNIIGKNPQFVKTSDIESIDIDTPLDFYIAEQLYKKLVIEK
                     KRLLE"
     CDS             complement(4246..4863)
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MKILSLIRTLKSVLYAYDSDQWEKRVGALGKDSYLRGPISCANPS
                     LIFVGNHSHIFGQANYIIRNGKFIVGDYTGIAQGLTVITGNHISEKGKLFNDCLQLDEQ
                     DVIIEDDVRIGAFVTILPGVKIRRGAIIGAGTVLRFSIPPYAVVTGNPAKIVGFRMNPQ
                     EALEHEAALYPEEKRLSADELFDNYEKYYFNRMSEIIEYLKV"
     CDS             complement(4860..5105)
                     /NRPS_PKS="Domain: PP-binding (11-76). E-value: 9.5e-10.
                     Score: 30.8. Matches aSDomain:
                     nrpspksdomains_ctg49_7_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_7"
                     /sec_met_domain="PP-binding (E-value: 2.3e-09, bitscore:
                     30.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHDIYTSLNQILGKIIGDTKLDLNELTTTDEISGWSSLVQTQL
                     VVEIEKHFNCRLTLRDIMKIDKNISSIVTLIDNKLQ"
     aSDomain        complement(4878..5072)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg49_7_PP-binding.1"
                     /evalue="9.50E-10"
                     /label="ctg49_7_PP-binding.1"
                     /locus_tag="ctg49_7"
                     /protein_end="76"
                     /protein_start="11"
                     /score="30.8"
                     /tool="antismash"
                     /translation="QILGKIIGDTKLDLNELTTTDEISGWSSLVQTQLVVEIEKHFNCR
                     LTLRDIMKIDKNISSIVTLI"
     CDS             complement(5110..6621)
                     /NRPS_PKS="Domain: AMP-binding (16-408). E-value: 9.2e-71.
                     Score: 230.4. Matches aSDomain:
                     nrpspksdomains_ctg49_8_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     210.7; E-value: 5.1e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_8"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-73, bitscore:
                     241.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKIDVLERLSTKMAKYLDQNCFCIKDKYYTYRELSILTAKIQ
                     QEIRNQYTETTPVGLVNNDDIYTYASILALWYEGLAYVPLHPLQPIARCIDIIEQVNIQ
                     LIIDSTEMSRYVDKYNVLYPQNNSNTDVVFPVINNIDDEALCYILFTSGSTGKPKGVQL
                     NRRNITSFVAAFENAGIVLSHEDRCLQCFDLTFDVSVQSYLMPLLNGACVYTLPLDCMK
                     YACSADLIERYKLTFGAMAPSMVRFLKPYFDELDMSSLKKCILTAEASNLSLVKDWKKC
                     AYNAELYDFYGPTEATIYCTYYKLPDDINQTKNRNDILFIGKPMSGIKAVLISPDGIVL
                     NKGIGELCVAGEQVTPGYWQLFEKNKEAFLTISIDNKDYRFYKTGDLCQFDKDGDLEYI
                     GRIDFQAKVQGYRVELGEIECKIREFTKCDTVVLAIKEDNNDDILVGFVESRLVDEKQV
                     YVYLREQLPPYMIPKSIISLAQFPLNNNGKIDRKQLIEIFKTHNK"
     CDS_motif       complement(5365..5430)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg49_8_0003"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg49_8"
                     /protein_end="419"
                     /protein_start="397"
                     /score="32.0"
                     /tool="antismash"
                     /translation="YIGRIDFQAKVQGYRVELGEIE"
     aSDomain        complement(5398..6573)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg49_8_AMP-binding.1"
                     /evalue="9.20E-71"
                     /label="ctg49_8_AMP-binding.1"
                     /locus_tag="ctg49_8"
                     /protein_end="408"
                     /protein_start="16"
                     /score="230.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AKYLDQNCFCIKDKYYTYRELSILTAKIQQEIRNQYTETTPVGLV
                     NNDDIYTYASILALWYEGLAYVPLHPLQPIARCIDIIEQVNIQLIIDSTEMSRYVDKYN
                     VLYPQNNSNTDVVFPVINNIDDEALCYILFTSGSTGKPKGVQLNRRNITSFVAAFENAG
                     IVLSHEDRCLQCFDLTFDVSVQSYLMPLLNGACVYTLPLDCMKYACSADLIERYKLTFG
                     AMAPSMVRFLKPYFDELDMSSLKKCILTAEASNLSLVKDWKKCAYNAELYDFYGPTEAT
                     IYCTYYKLPDDINQTKNRNDILFIGKPMSGIKAVLISPDGIVLNKGIGELCVAGEQVTP
                     GYWQLFEKNKEAFLTISIDNKDYRFYKTGDLCQFDKDGDLEYIGRIDFQAKV"
     CDS_motif       complement(5515..5592)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg49_8_0002"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg49_8"
                     /protein_end="369"
                     /protein_start="343"
                     /score="23.8"
                     /tool="antismash"
                     /translation="IGELCVAGEQVTPGYWQLFEKNKEAF"
     CDS_motif       complement(6133..6186)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg49_8_0001"
                     /evalue="1.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg49_8"
                     /protein_end="163"
                     /protein_start="145"
                     /score="26.6"
                     /tool="antismash"
                     /translation="CYILFTSGSTGKPKGVQL"
     CDS             complement(6632..7483)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MITLRGLFRDLKFLIGCFVYLVKHYSLFSGLKFQGRQERIVYLLC
                     NGPSLKNDMETIKKLKGVDFIVVNFMANDSLFWEIKPQYYTLMDPLFFTNRRENRYMER
                     LEVLFDSFNRIDWEMIIFLPIQYEKSFREFSKINNPKIKIMVLNTFSSYVASDNVRHFC
                     YRKGYAMPNAQTVAIESIFAMLNMGYSTIYLYGVDHTFLEGLKVNDKNELVHVYQHFYE
                     NEPKIIPVTDAFGYHNSLTKELQTIVNIFASHEQCRKYADHLGANIYNLTKGSQIDSYE
                     RR"
     CDS             complement(7480..8925)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_10"
                     /sec_met_domain="Polysacc_synt (E-value: 7.7e-22, bitscore:
                     71.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRTKQLGKNTLLVFIGSFGAKIISFIMLPFYTRWLSVTDYGVVD
                     MISIYQSLLTDFLTAAISTSIFIFPKGVAFHRQKEYFSSGLIFAFFAFIVAAFLFYIVR
                     SSFNLFSVSNSFTDYTVWIYIMIFITFIQTYLQQFCRSIDKMYVFTLIGILLTLCTGIF
                     SFIFIPKNGVYGYLIAMVLSNVVVAITTFFIAKLYKYVSLKSFNKVSLKEMLKYSIPTI
                     PNVLMWWVLGSLNRPILEGTVGLSGIGILAVAQRFPNAASLVFSIFGNSWQISVLEEYK
                     MNDFPLFFNRVLAIFSIITCLGVLILSYISDWLVTFIVGNNFLSSSTYIPCLSLALFFL
                     CMNTIISPIFSAVRKSKYYLYSSIWSAVLTIGLNILLIPLIGIMGACISIVCSHALMTL
                     LRVKYTLIFVSVYLKEQYLFLGLLAVAFIVALSIGDSLMFRTMALLVAFLGVALVIRNF
                     DKRLNIKFLAIKLFKNKIKFKQS"
     CDS             complement(8927..9937)
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="MHILICNSNMFIPIVLTTILNNSEQRYLIYVDIPDIYTFLGKLNL
                     PNNCMLLKYPHNINWKNANKAKQFIWNQLVHIDIKSITFYHTEYGELATWLISKYSRNT
                     TIYFQSPFPSFCFKKKISLKALKLFLVYKIVYNTDIVPMNYGNDILPSISPRFFKKNNV
                     INKNAVIDDELVYNYVSEKLNLNNNNRSILLVTGSNIAAGFCDETDYGKIINSILSALG
                     KDKFMIKCHPRFDDLLSIEKMLPAIPKYVPGNLILPLFDCYIGLCSTLLSEAANVGKCS
                     ISILNLLNIDFKLKSVLKDSIEIKLKSGSTIYYPNSISELNDIVKRSCNNNITMI"
     CDS             complement(10126..11169)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 146; E-value:
                     2.3e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_12"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.2e-12, bitscore:
                     39.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESIHIISQDLSLMRALERINQITDNNPLVLFAIDSNSAMRGTLT
                     DGDVRRALIKGVGVDAPIAEVMHRDFNFLRRGVNDGVEDIHHQRELKMRLVPILDEDNH
                     ICEIINLERYITKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSY
                     GLNHISVTVNYLGDQIEEHFQEERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMN
                     SDLFTNIDFEDFFLHFCQHDADMSVAAVPYVVKVPYGVFNLKGREIKGVTEKPTISYYA
                     NAGIYLIKRKLFDLIPDDIFFNATDFMDKLIELGHKVIRYPISGYWLDIGQHDELARAR
                     EMVKHLK"
     CDS             complement(11176..12534)
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MAKGIVYICHHIDTEGPMWENIEELFDRISNIFNFEKYGIDLLPT
                     YENLEKLQSGDINVPEKMKAEIYNAVSPHTVGFKRNWGMIEEMLSRIMRPEFRSEMKDS
                     FGGGWIYNWHVMDHVGFDSVNPRHRDYGYHNVLDFYQYMIKVTSSTEDAIHWHFHPVPP
                     DGVCNHTAYNYENCFPTLHSIITRRLIDRRIFPVVNRPGFHSERIDSNFFLEQWIPFDP
                     ANQAVDAEEQPKYQTDMVNGHAGDWRGAPADWSLYHPDFYDWRRSGNMNRWVARILNMM
                     ARHRSITVEEIEKAFVKAEGGDNVYLGITDHDWREMSDEINEFRDMLQFVSKRHPEVKF
                     KFSESVDAFRKVIGYTVQECIDNKVQLDYRWQDNVLHVYVVNGEPFGPQPYLAIKDVVG
                     HYIHDTFDFNVYKTSYCYTFCADTVEIANVEKIVVATNDKYGNTCILNVEKPQ"
     CDS             complement(12557..13294)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     146.1; E-value: 2.2e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="MILKDKVIIITGGSGLIGRECVKDARKKGATVINADIAVDTDLDK
                     GGYHLDMSDDTSVTSLVNMVYEKYGRIDGMANVAYPRTKDWGVFFEDIPIESWRKNVDM
                     QLNACFLLCQKTLAVMKEQGFGSIVNFGSIYGVVGNDFTIYEGYGGTSPAAYTAVKGGI
                     INFSRYLASYFGKYGVRVNVVSPGGIIDKQHPSFIERYSIKSPLKRMGHPEEIAPAVSF
                     LLSDEASFITGHNLMVDGGWTAI"
     CDS             complement(13278..14198)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 65.9; E-value: 6.4e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MRVLVVGLGSIAKKHIAALYQIDPSVELFALRSNKEAKSWNGITS
                     LYDWNELNAYQFDFAIISNPTSEHIPAIRQLLPYRIPLFIEKPLQSEIVQDCLISEVKE
                     AGIITYIGCNLRFHECLLQVPSLITNHRVNEVNVYCGSYLPDWRPQVDYHTVYSANPEM
                     GGGVHLDLIHELDYIYWLFGYPEGMRKIFSHKSSLEICACDYANYLLEYPQYNINIILN
                     YYRRDYKRTLEIVCEDATYNIDLANNTIAVNGKLIFSSDKRIIDTYFPQMKYFIDCVQN
                     HQHSFNSIEDANNVLKICFGYDTER"
     CDS             complement(14195..14917)
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MNMLITICARGGSKGIPGKNIKPLCGKPLIGYTIDVAKRFAAETG
                     NTVIALSTDSDEIIHVAAECGLQSDYKRSDYLANDTCGKIDAIKDIVLYSEKNQGITFD
                     YILDLDVTSPLRTLEDLKEAFNLIQSDEKAVNLFSVSEPGRNPYFNQVEQKENGYYAQV
                     KALDINVLSRQAAPKVYDMNASFYFYKRCFFDLGYKGAITDRSLIYLMNHTCFDLDHPI
                     DFEMISFLLENNKLDFTL"
     CDS             complement(14922..16076)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_17"
                     /sec_met_domain="Epimerase_2 (E-value: 3.9e-87, bitscore:
                     285.5, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKICVATGTRAEYGLLSRLMRLIDESADCQLQVIATNMHLLPEY
                     GNTYQEIERDGFHIDTKVPMIKLSDDAYGVINSMAEEMKGMNEALLQLHPDMVVILGDR
                     YEMLVTATVAMLQRIPIAHLHGGEISEGAVDDSIRHAITKMSSLHFTSTEDYRHRVIQL
                     GEQPDRVFYVGAIGVENLKIIPLLSKRELEDSLSFTFDRETILVTYHPVTLGNRSSKDE
                     IDDFLSALDAFPGLKVLFTMPNSDQGGDIIRQAIDTYCSMHPNRCKCYSSLGLKRYLSV
                     LQYVEAVVGNSSSGILEVPSTHIPTLNIGDRQKGRIHGDSVYNCASDKESVIKGLAMVL
                     SSSFKEIALKASNPYEKENTAQSVFDVISTYPLDELKHKSFYNL"
ORIGIN
        1 ttgttcgcag cgaagataga ggtttaaatt atgagccaat ttttgactgc ttaccttcgt
       61 tgcttaaatt tttctgactg atatgaacac cattgctcat gcggatatcc accaggattc
      121 gaagttcggt atgacaaaaa agccgaggat ccgattctga cttttgttcc gggagtggcg
      181 aaggactttc cggcatttcc gattccgttg agggagcacc caaaaccaga acgggaatta
      241 tcttcttccg ggtatccttg taccatttgg aaaataggtt ataaggaact tggttggaca
      301 tacaaaattt ttatgtagaa acaccagcag gaatcccttc caatttatag cgcaaaaata
      361 gacgctcaaa attattgtaa ctatacataa acttggattt tgatttaacg aaagcaaagg
      421 tctgactttt ttatcggtta tcctatacgt catttttgga cgctaacgag atagaattct
      481 attatgaaat tcacttcagc agcccctcta tttccattgg attatcagct actcccacca
      541 cgtttttact agaaagttct cttacacttt ctctaaaacc aaaaccgtaa gttacagcaa
      601 taaaatgaat atcagcctct tctgctcctt ccaaatcatg atatgtatca cctactaaaa
      661 ccacttcgct attatccact gacatttcag atatacaaag ataaacaata tcactcttac
      721 ggagtttatt atcattgtct gcaccatgaa cgacatcaca atattctaaa ataccaaaat
      781 gctttagaat atccatagca taatcttcac gcttatatgt agctactcca ataagaaacc
      841 ctttttgctt caactgtttc aacaagtcaa tgatacctgg atataaagct gctttaaaca
      901 aagcacagtc tttataatag gcacgaaata tatccgcccc cttttgaaca tcttcatctg
      961 ataatctaaa atgacgtttt aaagattctt gaataggggg gcctataaat gttgatacct
     1021 cgtcagagga tatagagggg agttgcatta cagacagcgt gtgcaagaca ctacatgcta
     1081 ttccttcact tgtattcaaa agagtcccat ccaaatcaaa caggaccgct ttaatagttt
     1141 gcttatctga catcatacaa actttctgta atgaaatgaa gacggattga ctgatttatt
     1201 ttagataaat catctgacaa aagatcatta taactttcat ctttagttga tgaaagttcg
     1261 taatcgcgat cataataatc attaggtgta ttggtaaatc catcaaaacc tgcaagatat
     1321 acttctgtga ttccaattct tattaaagcc ttaagcagca aaacaagagc attatcagga
     1381 ttttcagatt ctttattcaa cagtgactca taattgagaa cataattagg catatagtca
     1441 catgcggtaa cattagatgt aagaatcagt ttagagccaa tactgtcacc gtgctgaata
     1501 tccacaaact tagcgtaacg cttggcatta cttataaaag tataatcaat agaataaagt
     1561 tttgtataga aatttacaga aaagacaact ggatcattcc ccgaaatgaa taactccacc
     1621 cctttttttt gctccttgac agtattgccc ggaccaatta tcaatacagg tttgtcactc
     1681 gctgcttcaa gttcaacttt caattgctgt aaagcctcag tatcgtcctt cgctctattc
     1741 tgataatcga gatatgcttg ctctatccat tgtttgttat aaagcaactt tatttcttca
     1801 ggtattgagg aaagaatttc attaattgag ctgacagaca atgtactctt tttgagaaga
     1861 tactggacat aggacggatg acatcgttgc atcgaagcaa tgtagaaatc atatttgtag
     1921 ccccaataat gtttctgata aatcggcatc aaatctgtat caacaatctc caacaactgg
     1981 tttaaatcgt aatgccctcc gtaatattcg tttaaatgca tcgctaaaag ttcgctggca
     2041 caatttccgg cactttttcc catgccataa accgtagaat ctgccaccag tgttcttttg
     2101 gtacttttct ccaaaaattt aattgtattg ctaaagccca attggaagtt attgtgctca
     2161 tgatacccca ttttaatact agggtccaaa ttgttgtcta tcaagtagaa atatcgagcc
     2221 atactgctat tatcaagcaa accataagtg tctacaatag aaaaagcata aggtttaatt
     2281 tcattgatgc gatttacata ctcaagcatt tcaatgtcac tataggctgt aattgaaatg
     2341 gcttgtatga agagcttata gcctttttcc ttaatagctt tacagaatgg caaagcttga
     2401 tctatttttt ctttcttgaa gataactcga ataccatcaa taaaagtaga atcacaagaa
     2461 cctatactat caagagaaca agtgccaaag tcaatcattg ctacaggtat cgcttttcct
     2521 ttttttacag aaccaaagat tttattgata gcttctgtac ttggcatgat ggaacgattt
     2581 atatcaaatt ctcttctgtc atccaagaaa cccacttcaa tataatcagc acctgctgct
     2641 tccaatcgct tataaatacc cgtaatagta ctatgaccaa aatcccaatc attgacatag
     2701 ccaccatcac gtagcgtaca atctaacatt aatacttttt tttccatagt tcaagcttgt
     2761 tttgtcacca ttatttcttt taccttctcc aagtctcgag gggtatcaac agaaagagat
     2821 actgaatcca ccaatttata tttgatgtga atcttattct ccaaaaatcg ctgaagtgtt
     2881 acatcctcga tattctccag atagccttta ggtgtggaga caaaaaaatc taaagcttgt
     2941 ttattatagc attccacacc caccactttt ttatatttaa aaagcacagt cttataagga
     3001 aacggaatag gtgctcttga taacaataca cattcatctg aatcattagt cacaatctta
     3061 atatttgcgg gatcaataac ttctgctggt tctgtgaagt atcgacagag accaccaaca
     3121 tacatatggc tattatcaac atcttgcgaa ggaaaaacag cctctattat atccgggcca
     3181 atcaaaggtt catcaccgca aactacaaca taatagtcag ctgcaatatt atcacttacc
     3241 tcatgaatcc tatgcacatg agttggatga tttgactggg tcatgataaa cttcatacca
     3301 taattcgagc acacatcagc aattcgttga tcgtctgtgg ctacataaac ctctaagaat
     3361 tcttttactt taattacctg attgtaaacc caccaaatca ttggtcttcc aaaaatatca
     3421 gccaatggct ttccaggaaa gcgtgatgat tggtatcgcg caggaataat agctataatc
     3481 ttatccataa atataatgag ttattcttta tatctgcatc attcagcgaa ataccaatca
     3541 atcccaaaac ttattccagc agcctcttct tttctataac taacttttta taaagctgct
     3601 cagcaatata gaaatcaaga ggagtatcaa tatcaatgga ctcaatatcg cttgtcttga
     3661 cgaattgagg atttttaccg atgatattgg agtttttgat aagatcttct ttcctgacta
     3721 ctgttacacc aaaattcaac gccaccacat cagggagatc ctgggagtta ggtgcatgag
     3781 cagggtcata attcatcgga tcaccatcaa gccaaagaaa ttctttaaca gacgaaacag
     3841 tagccaagca atcgtaatcc gaagtagaaa taaattgatt aatacactga gatacagttt
     3901 ctggtttaat gaagggcgaa gtacaggggc aatagacaaa aagatcggta tctgtcactt
     3961 cacctaaatg tctaaaaaat tcacttccgc tacattgtga agaggcgtaa tactcttcac
     4021 gacggtgagt agtcaccccc ccccgataac ttttattaac aatttctatt gctaactccg
     4081 aattagtgtt tacaacaata gatgtaagtt caggaacttg cagaagattt ttaattttca
     4141 gttccatcaa attagtatcc gcaaaggcac gcaagttttt atccttgaca cgttgtgatc
     4201 cactgcgaat aggaataacg gcagtaattt tcattatttt gtattttata cttttagata
     4261 ttctattatc tcactcattc gattaaagta atacttttca taattatcaa ataattcatc
     4321 tgcggacaag cgtttttctt ccggataaag agccgcttca tgttcaagcg cttcttgcgg
     4381 attcattctg aatcccacaa ttttagcagg attacctgta acaacagcat aaggaggaat
     4441 agaaaaacgc aatactgttc cggcacctat tatagcacct cttctaattt tcactccagg
     4501 caaaatagtc acaaaagcac cgatgcgaac atcatcctca ataataacat cttgctcatc
     4561 cagttgcaaa caatcattaa acagttttcc tttctctgaa atatgattac ctgtaataac
     4621 agtcaatcct tgtgctatcc ctgtataatc accaactatg aatttcccat ttctgatgat
     4681 atagttagct tgtccaaata tatgagagtg attgcctaca aatattaaac taggattagc
     4741 acaagatata ggtcctctaa gataactatc ttttcctaaa gcccctacgc gtttttccca
     4801 ttggtcagaa tcataagcat ataacaccga cttaagagtt cgaatcaaac taaggatttt
     4861 cattgcaact tattatctat caatgttaca atggaagata tattcttatc tattttcata
     4921 atatccctta gagtcagacg gcaattgaaa tgcttttcaa tttcaacgac caactgagtt
     4981 tgtacgagtg aactccaacc agaaatttca tctgtagtag tcaactcatt tagatccagt
     5041 tttgtatcac ctattatttt ccctaaaatc tggtttagag aagtataaat atcatgtctt
     5101 tccattattt tatttattat gagtcttaaa aatttcaatc aattgttttc tatcaatctt
     5161 accattgtta tttagtggaa attgagcaag actaatgata gattttggta tcatatatgg
     5221 aggtaactgt tcacgcaaat aaacatagac ttgcttttcg tcaactaatc ttgattcaac
     5281 aaaaccaacg agaatatcat cattattatc ttccttgatg gcaagcacta ctgtatcaca
     5341 tttagtaaac tctctaatct tacattcaat ttcaccaagt tctacacgat aaccttgaac
     5401 cttagcctga aaatcaattc ttccaatata ttcaagatct ccatccttgt caaactgaca
     5461 caaatcaccc gttttataaa atctataatc cttattatca atggatatag taaggaaagc
     5521 ttctttattt ttttcaaaaa gctgccaata tccaggagta acttgttcac cagccacaca
     5581 caattcacca attcctttat tcaggactat cccatcgggt gaaataagaa cagcttttat
     5641 tccactcata ggtttcccaa taaacagaat atcatttcgg tttttagttt gattgatgtc
     5701 atcaggcaac ttataataag tacaatagat agtagcttcc gtagggccat aaaaatcata
     5761 aagttcagca ttatacgcac attttttcca atctttcacc aaggagagat tagaagcttc
     5821 ggcagttaga atgcatttct taagagatga catatccaat tcatcaaaat acggttttaa
     5881 aaatctgacc atagaaggag ccatagcacc aaatgtaagt ttgtatcgtt ctattaaatc
     5941 ggcagaacaa gcatacttca tacaatctaa tggtaaagta tagacacatg ctccatttaa
     6001 taaaggcatc aaataagact gtacagacac atcaaatgtc aaatcaaagc attgcaagca
     6061 tctatcttca tgggataaaa cgataccagc attttcaaaa gcggcaacaa atgaagtaat
     6121 attacgtctg ttcaattgaa caccttttgg cttacccgtg ctaccagaag taaatagaat
     6181 atagcacaat gcttcatcat ctatgttgtt aatgacaggg aatacaacat ctgtattgga
     6241 attattttgt ggatatagaa cattatattt atctacatag cgtgacatct ctgtagaatc
     6301 aataatcaat tgaatattca cttgttcgat aatgtcaata catctagcaa taggttgcaa
     6361 gggatgcaag ggaacataag ccagtccttc ataccacaaa gccaagatag aagcataggt
     6421 ataaatatca tcattattaa ccaatcctac cggagtcgtt tcagtatact gatttcttat
     6481 ctcctgttga atctttgcag ttaaaataga aagttcccga taagtataat atttatcctt
     6541 aatacaaaaa caattttgat ctagatactt agccattttt gtactaagtc tctccaacac
     6601 atcaatctta aagttattca tcttctctca tttatctacg ttcataacta tcaatttgtg
     6661 accccttagt caaattataa atattagcac ccagatgatc agcatatttg cgacactgtt
     6721 catgggaagc aaaaatattg actatggttt gcaattcctt agtaagtgaa ttatgataac
     6781 caaaagcatc ggttacaggt attatttttg gttcattttc ataaaaatgc tgatatacat
     6841 gtacaagttc attcttatca tttactttca aaccttcgag aaatgtatga tcaacaccat
     6901 aaagataaat agtactatat cccatattaa gcatagcaaa aatagactca atagccactg
     6961 tttgcgcatt aggcatagca tacccttttc tataacagaa atgccttaca ttatccgagg
     7021 caacgtatga tgagaacgta ttcaatacca taattttaat ctttggatta ttaatctttg
     7081 aaaactcacg aaaggacttt tcatattgta tgggtaggaa aattatcatt tcccaatcaa
     7141 tacgattgaa ggaatcaaat agtacctcca atctttccat atatctattc tctctcctat
     7201 ttgtaaaaaa caacggatcc atcaatgtgt agtattgtgg tttaatctcc caaaaaagag
     7261 aatcgttggc cataaagttt accacaataa aatcaactcc tttcagcttt ttaatagtct
     7321 ccatatcatt ttttaaagaa ggtccattac ataacaaata cacgattcgt tcttggcgac
     7381 cttgaaattt aaggccagag aaaagagagt aatgttttac aagatacacg aaacatccta
     7441 ttaggaattt taaatctcga aataatccac gtaatgttat catgattgtt taaatttgat
     7501 tttatttttg aataatttta tagctaaaaa tttaatatta agacgtttat caaaattacg
     7561 aataactaga gcaacgccga gaaatgctac taaaagtgcc attgttcgaa acatcaaaga
     7621 atcgcctatc gataacgcta caataaaagc aacagctaac aaacctaaga acaaatactg
     7681 ttcttttaag tagacagaaa caaaaatcaa agtatattta acccttaaca atgtcatgag
     7741 tgcatgagaa caaacaatac ttatacaagc tcccatgatg ccaattaacg gaatcaacaa
     7801 aatattaagg cctatagtca gcacagcact ccatatactt gaatacagat aatacttact
     7861 ttttcgtaca gcagagaata tgggactaat aatcgtattc atgcataaga aaaagagagc
     7921 taatgaaaga cacggtatat aagtagacga agataagaaa ttattgccta caataaaagt
     7981 taccagccaa tcggaaatat aagataggat gagcactcca aggcatgtaa tgattgaaaa
     8041 aatggctaaa acacgattga agaacaaggg aaaatcgttc attttgtatt cttccaatac
     8101 tgaaatctgc catgaattac cgaatataga aaacactaac gaagctgcat ttggaaaacg
     8161 ttgcgctact gctaaaatac cgataccaga aagtcccact gtaccttcta agatgggtct
     8221 attcaaagaa cccaacaccc accacattaa aacattagga atagttggaa tagagtattt
     8281 aagcatttct tttaaagaaa ccttattgaa ggattttaaa gaaacatatt tatataattt
     8341 tgctataaaa aaagttgtaa tggctactac tacatttgac aataccatgg caataagata
     8401 tccataaacg ccgtttttag gtataaatat aaaagaaaag ataccagtac ataatgtgag
     8461 aagaatacct atcaatgtaa atacatacat tttatctata ctcctacaga attgttgcaa
     8521 atacgtctga atgaatgtaa taaatatcat tatataaatc caaacagtat aatctgtaaa
     8581 actattgctt acgctgaata gattaaaact tgatctaact atataaaata gaaatgcagc
     8641 tactataaat gcaaaaaaag caaatatcaa gccagaagaa aaatattctt tttgacggtg
     8701 aaatgctacc ccttttggga atataaatat tgaagttgaa atagcggctg ttagaaaatc
     8761 ggttaaaagt gattggtata ttgatatcat atctactacg ccataatcag ttacgcttag
     8821 ccaccgcgta taaaacggca acataataaa tgagataatt tttgcgccaa aacttccaat
     8881 aaaaactaac agcgtattct ttcctaactg tttggttctc cccattttat atcatagtta
     8941 tgttattgtt acatgaacgt ttcacaatat cgttaagctc actaatacta ttaggataat
     9001 atatagtaga accactcttt aattttatct ctattgaatc tttaagaact gatttcaatt
     9061 taaaatctat attcagtaga tttaaaattg agatactaca tttaccaaca tttgcagctt
     9121 cacttaacaa agtagaacac aatccaatat agcaatcaaa caatggaagg atgagattgc
     9181 ctggtacata tttaggaata gcaggaagca ttttctcaat cgataataaa tcatcaaatc
     9241 ttggatggca ttttatcata aatttatcct ttcctaaagc agataatata gaatttataa
     9301 tttttccata atcagtttca tcacaaaaac cggctgcaat attcgaacct gtaactaata
     9361 gaatggaacg gttattatta ttcaaattaa gtttttcact tacataatta taaaccaact
     9421 cgtcatctat cacagcattt ttatttatta cattattttt cttaaaaaac ctaggagaaa
     9481 tagaaggtaa tatatcatta ccataattca ttggtacaat atcagtatta taaacaatct
     9541 tatagactaa aaacagtttt agcgccttta acgaaatctt ttttttaaaa caaaaagaag
     9601 gaaaaggtga ttgaaaataa atcgtagtat ttctactata tttagaaatt aaccaagttg
     9661 ccagttcgcc atattcagta tggtagaacg taatactttt aatatctatg tgtacaagtt
     9721 gattccatat aaattgtttt gccttattag cattcttcca attaatatta tggggatatt
     9781 ttaggagcat acaattattc ggcaaattga gtttgcctaa gaacgtatat atatcaggta
     9841 tatctacata aatcaagtaa cgttgttcgg agttatttag tattgtagta agtactatag
     9901 gaataaacat gttactatta caaatcaaaa tatgcattct atttatcttt tactgcaaat
     9961 gtaaactctc aatctcttcc acttcgctaa gaatcagcaa agcaaaaaac taagcaatta
    10021 aaaagttatt ttagttttgt ccagaagcta tttgccccct tgcaaatgac agctgcctaa
    10081 ttgcctggca ccaataactg ctattttata tattgtattt taaatttatt tcaaatgctt
    10141 caccatctct cttgccctcg ctaattcatc atgttgacca atatccagcc aatatccact
    10201 aattggatag cgaatcactt tatgtcccag ttcaatgagt ttatccatga agtcggtggc
    10261 attaaagaag atatcatcag gaataaggtc aaacagtttg cgtttgataa ggtatatacc
    10321 ggcgtttgca taataactga tggtgggttt ctcggtaacc cccttgattt ctcgtccttt
    10381 gagattgaac acaccgtatg gcactttcac cacatagggc acagctgcca cactcatgtc
    10441 ggcatcatgc tgacagaaat gaaggaaaaa gtcctcaaaa tcaatattcg taaagagatc
    10501 tgagttcatt accagcaccg tatcattgta aaaagtttcc acgaacttga tactgccaat
    10561 ggtacctaga tatttcggtt cacgcacagt aactatcttc accccatcgc gttcctcctg
    10621 aaaatgttcc tcaatctggt cgccaagata gttaaccgtt acagatatat gattcaaacc
    10681 gtatgaaagc aaacgatcaa tattataatc aatgatacac ttgtcaccta ccttaattag
    10741 gggcttagga gttttttccg ttaacggacg aaggcgttcc cccttaccac ctgccattag
    10801 tacagcatca atcggcagtt tggttatata acgttccaaa ttgataatct cgcaaatatg
    10861 attatcttca tccagtatag gcactaaacg catctttagc tcgcgctgat ggtggatatc
    10921 ctccactcca tcgttcacgc cacgacggag gaagttgaag tcccggtgca taacttctgc
    10981 aataggagca tccacaccga cacctttaat caaggcacgc cgcacatcac catcggtaag
    11041 ggttcctcgc atagcagagt tggaatcgat ggcaaaaagc accaaaggat tattgtcagt
    11101 aatctgattg attcgctcta atgccctcat taatgataaa tcttgcgata taatatgtat
    11161 agattccata attatttatt gtggcttttc tacgtttagt atgcaggtat taccatattt
    11221 atcatttgtt gccacaacta ttttctctac atttgctatt tccacggtat ctgcacagaa
    11281 tgtataacaa taacttgtct tatatacatt gaagtcgaat gtatcatgta tgtagtgacc
    11341 tacgacatct ttaatagcca aatagggctg aggaccaaat ggttctccat ttacaacgta
    11401 aacatgaaga acattatctt gccatctgta atcaagctgg actttattat cgatacattc
    11461 ttgcactgta tatccgatta ctttacggaa tgcatcaacc gattcagaaa atttaaactt
    11521 tacctcagga tgtctttttg aaacgaattg aagcatatca cggaattcat taatttcatc
    11581 agacatctca cgccaatcat gatcagtaat gcctaaataa acattatcac caccttccgc
    11641 ttttacaaaa gctttttcaa tttcttctac ggtaatcgaa cgatgacgtg ccatcatatt
    11701 cagaatacgt gcaacccatc tattcatatt ccccgaacgt ctccaatcat aaaaatcagg
    11761 atgataaagt gaccaatcag cgggtgcacc acgccaatct ccagcatgac cattaaccat
    11821 gtcagtctga tatttgggct gttcttcagc atcaactgcc tgattggcag gatcaaaagg
    11881 aatccattgc tctaagaaga aatttgaatc aatacgctcc gaatgaaatc caggccgatt
    11941 aacaactggg aaaattcttc tatcaattaa acggcgggtg ataatactat gcagcgtagg
    12001 aaaacaattc tcatagttat acgctgtatg attacaaacg ccatcaggtg gaactgggtg
    12061 aaaatgccag tgaattgcat cctcggtaga acttgtaacc tttatcatgt attgatagaa
    12121 atccaataca ttatgataac cataatcgcg atgtctagga ttgacagagt caaaaccgac
    12181 atggtccata acgtgccaat tataaatcca tcctccacca aacgaatctt tcatttcact
    12241 acgaaattcc ggtctcataa ttcgactgag catctcctca atcattcccc agttacgttt
    12301 aaaaccaact gtatggggag atacggcatt gtaaatttca gctttcattt tctcaggaac
    12361 attaatgtct cctgattgta acttttccag attttcatag gtaggaagta agtctattcc
    12421 atatttttca aaattaaaga tgttactgat tctatcaaac agttcctcaa tattttccca
    12481 catgggacct tccgtgtcaa tatgatggca tatatataca attcccttag ccataacgat
    12541 ttatatgttt taaatgttaa attgccgtcc atcctccatc caccatcaga ttatgacctg
    12601 tgatgaatga agcttcatca gacaataaaa aagatacagc aggagcaatc tcttcggggt
    12661 gccccatacg tttaagaggt gactttatag agtatcgctc gataaatgaa ggatgctgct
    12721 tatctataat gcccccagga gatactacat taacacgcac tccatacttg ccaaaataag
    12781 aagcaaggta gcgtgagaag ttaatgatac cgcctttcac tgcggtataa gcagcaggag
    12841 atgttccacc atagccttcg taaatggtga aatcattacc aaccacacca tagattgaac
    12901 caaaattcac tatagaaccg aatccctgct ccttcattac agccaatgtc ttttggcata
    12961 ataaaaagca ggcattgagc tgcatatcaa cattcttacg ccatgattct atagggatat
    13021 cttcaaaaaa aactccccaa tctttagtac ggggataagc cacatttgcc atgccatcga
    13081 ttctaccgta tttctcgtag accatattga cgagagaagt gacggaggta tcatcggaca
    13141 tatcaagatg ataaccccct ttatcaaggt cggtatctac tgcaatatct gcattgataa
    13201 cagtagcacc tttttttcgc gcatctttca cacactcacg accaataaga ccggagccac
    13261 ctgtgatgat gatgacttta tctttcagta tcatatccaa aacaaatttt taaaacatta
    13321 tttgcgtctt caatactatt gaaactatgc tgatgattct gtacgcagtc aataaaatat
    13381 ttcatttgtg ggaaataggt atctataatt cttttatcgg aagagaatat cagcttacca
    13441 tttacagcaa tcgtattgtt cgccaaatca atattatagg tagcatcttc acaaacaatt
    13501 tctaaagtac gcttataatc acgacgatag taatttagaa taatattaat attatattgt
    13561 ggatactcca ataaataatt cgcataatca caagcacata tctccaaact tgacttatga
    13621 gagaaaattt tacgcattcc ttccggataa ccaaagagcc aataaatata gtctaattca
    13681 tgaatcaggt cgagatgtac accacctccc atctccggat tagcactata tactgtatgg
    13741 taatcaactt gaggacgcca gtccggcagg tatgagccgc aatagacatt aacttcgttt
    13801 actctatggt ttgtaatcag acttggaact tgtaataagc actcatgaaa gcgtaagtta
    13861 caacctatat aggtaatgat ccctgcctct ttcacctcgg atattaaaca gtcctgcact
    13921 atttctgatt gaagtggttt ttctataaaa agcggtatcc ggtagggcaa caattgacga
    13981 atggcaggga tatgctctga agtaggattg gagataatgg caaaatcaaa ctgatatgca
    14041 ttcagctcgt tccaatcata taatgaagtg attccgttcc aggatttcgc ctccttatta
    14101 gaacgcaagg caaaaagttc aacagaaggg tctatctgat aaagggcagc aatgtgcttt
    14161 tttgcaatag aacccaatcc tacaaccaag actctcatag agtgaaatca agtttgttat
    14221 tttccagtaa aaaagaaatc atttcgaaat caatgggatg gtcgagatcg aaacaggtat
    14281 gattcatcag atagattaat gaacggtctg taatggcacc tttgtaaccc aagtcaaaaa
    14341 aacaacgctt ataaaaataa aacgaagcat tcatatcgta aacttttgga gcagcctgac
    14401 gtgaaagcac attgatgtcc aacgctttca cttgcgcgta ataaccattt tctttctgct
    14461 ccacctgatt gaaataagga tttctgcccg gttcacttac cgagaaaaga ttcaccgcct
    14521 tttcatcaga ctgtatcagg ttaaacgcct ctttcaagtc ctccaatgtc cggagcggtg
    14581 aagtcacatc caagtccaat atataatcga aggtaattcc ttggttcttt tctgaataaa
    14641 gcacgatatc cttgatggca tcaatcttgc cacaggtatc atttgccagg taatcggaac
    14701 gcttataatc cgattgcaga ccacattctg cggcaacgtg aataatttcg tcagaatcag
    14761 tagagagtgc tatgacagta ttgcctgttt cggcagcaaa tcgcttggca acatcaatag
    14821 tataccctat cagcggttta ccgcaaaggg gtttgatatt cttgccgggg attcctttgg
    14881 aacctccacg ggcacaaatg gtaatgagca tattcatact tctataaatt atagaatgat
    14941 ttatgtttca gttcatcaag cggatatgta gaaatcacgt cgaaaactga ttgtgccgta
    15001 ttctcttttt cgtaaggatt ggaagctttc aaagcgattt ctttaaatga tgaagaaagc
    15061 accatggcaa gaccctttat gacagactct ttatcacttg cacaattgta taccgaatct
    15121 ccatgaatac gtcctttctg tcgatcgccg atattgagtg taggaatatg tgttgagggc
    15181 acttccaata ttccactgga tgaattgccc accacagcct ctacatattg taagacagag
    15241 agatagcgtt tcaagcctaa agaggaatag cacttgcaac gattggggtg catcgaacaa
    15301 taagtatcta ttgcttgacg gatgatatca ccaccttggt cggaattagg catagtaaac
    15361 aataccttca atcccggaaa agcatccaat gcactgagaa aatcatcgat ttcatctttg
    15421 gaagaacgat tgcccaaagt gaccggatga taggttacca aaatggtttc tctatcgaaa
    15481 gtgaagctca atgaatcttc taattcccgt ttgctcaaca aagggattat cttcaggttt
    15541 tccactccga tagctcccac atagaatact ctatccggct gctcacctaa ttggattaca
    15601 cgatgacgat aatcttcagt ggatgtaaaa tgaagagaac tcatttttgt aatggcatga
    15661 cgaatgctat cgtctacggc tccttcactg atttccccac catgaagatg tgctatggga
    15721 atccgttgca acatggcaac ggtagccgtt accagcattt catatctgtc tcccaagatt
    15781 accaccatat cgggatggag ctggagaagt gcttcattca tgcctttcat ctcttctgcc
    15841 atggaattaa tcaccccata agcgtcatca gacaacttta tcataggtac tttagtatca
    15901 atatggaaac cgtcacgttc tatctcctga taggtatttc catattcagg aagcaaatgc
    15961 atattggtag caatgacttg aagctgacaa tctgctgact catcaattaa acgcatcaac
    16021 ctgctgagta atccgtactc ggcacgagta ccggtggcta cgcaaatttt tctcatatct
    16081 ctatcaattc atcttcattg aagtcacgaa cagctatctt gcctattatt tccggccatc
    16141 gcataggatt tataccacta cccggacgtt tcaccgtaag gttctcttcg gtgaacaact
    16201 cacctttctc aatgtctcgg gcagccacga tgctcttgcg tgcaacggct ttgttcttac
    16261 gttcggaagc ggagacggtt ttatgccccg tgccgatagc ctgctcaata ttacgaatag
    16321 cagttaccat ggcttttaat tcatcaggtt ctaatgatgc cttatggtcc ggtccgggaa
    16381 gagaacggtc gagtgtaaaa tgcttctcta ttatctcggc tcccatagcg acagccgcaa
    16441 tgggcacttc tatgccttgc gtgtggtcgg aataccctat cactacacca aactgtcgac
    16501 acatttcatt cattgcggag agattaacat ctaccattgg cgtgggatat tcggtattgc
    16561 aatgaagtac agatatttgt tccttccgca gaccgttatc tgtcaacacc tttatggctg
    16621 c
//
