LOCUS       c00054_gnlPro..        13496 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDAFDENC_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:36:07
            Original ID  :: gnl|Prokka|MDAFDENC_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13496
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13496
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[40:3496]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      41..3496
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13496
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13496
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             41..727
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_1"
                     /sec_met_domain="SucD_FumR (E-value: 1.8e-102, bitscore:
                     332.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSIGRKVVMSVTGIALVLFLTFHMAMNLVALFSEDAYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRAARGSERYAVNVKPKTVEWASQN
                     MLVLGIIVIAGLALHFANFWYKMQFAEIIGVHDLGAFGPTDGAAYIRETFGCPVFTVLY
                     LIWLAALWFHLTHGFWSALQTLGWSNKIWFERWKTIGNIYSTLVVLGFAAVVVIYFVKS
                     LACGAC"
     CDS             756..2720
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 193.8; E-value:
                     1.8e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.2e-59, bitscore:
                     193.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 120.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMATIDSKIPEGALAEKWTNYKAHQKLVNPANKRRLDIIVVGTG
                     LAGASAAASLGALGFKVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTI
                     KGGDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARG
                     QTGQQLLLGAYSALSREVQRGNVKLYTRYEMLDVVLIKDNEGVERARGIIARNLVTGKI
                     ERFAAHAVVIGTGGYGNTYFLSTNAMASNGSAAMQVYRKGAYFANPCFAQIHPTCIPVH
                     GDKQSKLTLMSESLRNDGRIWVPKKLEDAKALQAGTKKPTDIPDADRDFYLERRYPAFG
                     NLVPRDVASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEI
                     TDENPYKTPMMIFPAIHYTMGGIWVDYELMTSIKGLYAIGEANFSDHGANRLGASALMQ
                     GLADGYFVLPYTIQNYLSDQIQVPRFSTDLPEFVAAEKAVNDKIQRLMNIKGHRSVDSI
                     HKELGHIMWDFVGMGRTKESLTTALAKLKEVRKTFWSDLRIPGEANELNVELEKAIRLA
                     DFIEIGELMAYDALNREESCGGHFREEHQTPEGEALRHDDKFSYVACWKYTGEGKEPEL
                     IKEDLNYQFVKVQTRNYKS"
     CDS             2741..3496
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 36.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2e-26, bitscore: 83.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-06, bitscore: 19.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKDKGHFDTFQMKDIPGDTSFLEMMDILN
                     EQLINEGKEPIVFDHDCREGICGMCSMYINGHPHGPATGATTCQIYMRRFKDGDTITVE
                     PWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSINTGGIPDANAIPIAKPIADEAMDAAAC
                     IGCGACVAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKLVSISNIARLNREFIAAKLKD"
     CDS             complement(3493..4407)
                     /locus_tag="ctg54_4"
                     /transl_table=11
                     /translation="MSGLPCNERMDCTQCPKAVENSIHYTHNKKGFHLPPHKCETNILF
                     FLLKGQILINSEEYAGTIINPGEFVLQAIASKVEILAMTDSEGILYTFDDPKAFCYDRY
                     TYILKNVPPPLISEPLKIKPEIKLFLEGVTSYLNIDKICKELLEFKRKELYYLLAHYYT
                     DYELSPIVHSLSKYTNSFEYFILKHHKQIKSVEDFAQLGGYSVTTFRRIFKAIFNEPAY
                     EWMMKQRKESILYQLRYTEASISEICFEHGFESLSHFSNFCKKFFGDSPRNIRKREKEE
                     APGKKNAPPKAGHSQISSKTNRD"
     CDS             4688..4879
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="MEFVVSSDKKLLPYGMMNFADIRLDGYYYVDKTMYIPLIERSNRY
                     FFFIRPRRFGKSLTLNML"
     CDS             4973..5404
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="LVLYLNFSGIIGELHNYRAGLDAHCQTCFDYFCDIYAEYLPQGIK
                     EQLDAKNGAVEQLDYLYHECERVGQDIYLFIDEYDHFTNAILSDAESLHRYTKETHKEG
                     YLRAFFNKIKSGTYSSIKRCFITGVSPVTMDVVVSRGIL"
     CDS             complement(5568..6557)
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MKKILFAALAALAITSCSQNEIDGIDNGTPKSKNEIGVNTIVKKS
                     SRATVTSNSSFTSFKLHAYIIKSSDIATSGWGNAYMDGIEYKGGQGNWATTSGTFYWPI
                     TEMQFFGYTNDVTYTAPASSSAYPTISYTLPDTPADQKDIIVAYSKDITKPSDNTLNLT
                     FQHILTRINFAAKLADSNYTYTVESITITGAKGGAATYTFGGTEGKGGNWNITGSAPAS
                     GYSYTFDNTVTAKDDIYDYTQNNNSLMLYPQSLTDAKITVKYKTEKDNATFFNGSKEVA
                     LTGEWTNGQSIRYILTLPVGAEKMSVNTTYDEDWNATDNEQTPKTPVL"
     CDS             complement(6606..7577)
                     /locus_tag="ctg54_8"
                     /transl_table=11
                     /translation="MKKTRYAILVLLSSLLTLVGCSRREILDDYPVTGINIRLNWEGVT
                     DRLPEGVRIIFYPKDGQGRKIDTYLPAKGGEIKVPPGHYSAVIYNYDTEVVQIKDEGSY
                     ETIMACTGNCTGLGAEETKDMVWGPDNFYVATLDDVEIGKEEELPTLEVKPKSVVTTYT
                     FSIKTEGLKNVASILGSVSGMAECYHLGKGASLCRFAPIYCETSKGNGAIKGSFTCFGH
                     PKLTQARADITQFLNLIIVKVDGSKQEAKVEITEAVKPPEDKDEPGEGDEKPQEPEIEI
                     ELPDDEKIVVDDVEIPPDESGGGFDGNVSDWDDETNVELPVG"
     CDS             complement(7574..8830)
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MTLYFDLNARQIDKDYQGNGKTLTVLDSLLANPAHSIHLNSIILV
                     SPDLYNGKKEQGIPLGQKRSEEVKVFLCGKYPQVNTAQICIRKGEEYGDALRKLILDDR
                     LVPDREDVLALIDYHHNNPVKMQDFLQRLDAGIPYQYISDRVLPELRRTEIRVCLSYPE
                     ENGGKNSSAEQAARIEETEFIPIDRETTVTPMTMQVLPQKERTQVIIETEKTVIKAEKK
                     KETKEKRGEKPKEKAARRVQTVDNTVLALKNNLLYDLALAPNIEIEIPVGKRWSVNMEY
                     KSPWWSNSSKEICYQLISGGIESRYWLGNRELHNRLNGHFFGLYIEGGIYDFQFKGNGY
                     QGKYYGAAGFTYGYSTLLSRHLALEFSLGIGYLTTEYQKYTPYEGSLVWMSSGNYTFIG
                     PTKAKISLVWLITKKRGRK"
     CDS             9547..11430
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MKRHTNLLCLGAAVALLNACAPVVNAPEPVLPVPEKKQVDWQKME
                     TYAFVHFGLNTFNDREWGYGDSDPATFNPVKLDCEQWVKTFVAAGMKGVILTAKHHDGF
                     CLWPTGLTEYCIRNTPYKDGKGDIVRDLSEACKKYGIKFAVYLSPWDRHQANYGTPEYV
                     DYFYQQLHELLTHYGPVFEIWFDGANGGDGWYGGAKDSRTIDRKNYYDYARAYEMIDKY
                     QPQAVVFSNGGPGCRWVGNENGFAGATNWSFLRAGEVYPGYPKYRELQYGHADGNQWTA
                     AECDVSIRPGWFYHPEEDDRVKTVEQLTDLYYRSVGHNATLLLNFPVNRDGLIHPVDSA
                     NAVDFYKNVQKQLANNLLKGVLPIVSNERGGKYTAKAVTDGEYDTYWATEDSVTSAVIE
                     FEWPAPQKVNRMLLQEYIPLGQRVQSFVVEYNKEGEWLPVKLNEETTTIGYKRLLRFET
                     VTTDKLRINFTESRACLCINNIEAYYAGETPDVFTAKAEELKTYPFTLPQVDEAEAGKC
                     ADKDAATTCFVDGNTLLIDLGTEQTVSSFHYLPDQSEYNKGLIAAYEISVGTEANAVNQ
                     VVSSGEFSNIKNNPILQSVYFTPVTARYVLLKAVRMVENESPMGFAELGVQ"
     CDS             complement(11511..12626)
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="MTQDEQICSLALTRIPGLGLTGAFRLVSSLGSATRVFEHRKELSQ
                     LVPGVSEKIITALNNSEAFRRAEQELTFCQKNHIRCLTLNDEGYPSRLRECDDAPLALF
                     YRGNADLNTLHIINIVGTRHATPYGQDICTRFLADLSALCPDTLIVSGLAYGIDIHAHR
                     AALQNHFKTIGVLAHGLDRIYPAEHRKTAVSMLEQGGLLTEFTSGTNPDRQNFVKRNRI
                     VAGMSDATVVIESAAKGGALITAELAESYHRDCFAFPGRCNDEYSIGCNNLIRKNQAVL
                     ITSAEDLVKGMGWESSPKTEKTVQRELFPDLSEEEERIVKRLGKMPEGLQINTLVIDTN
                     IPVNRMSALLFELEMKGVIRALAGGVYRLIM"
     CDS             complement(12623..13030)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_12"
                     /sec_met_domain="HBT (E-value: 2.2e-11, bitscore: 35.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 6e-10, bitscore: 31.2,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKYIYELKMKVRDYECDLQGIVNNANYQHYLEHTRHEFLTSIGI
                     SFARLHEEGVDPVVARLTMAFKTPLRSGDEFVSKLYLKKEGIKYVFYQDIFRLPDMKVT
                     VKATVESVCVVNGRLGDSALFDETFAPYLSE"
ORIGIN
        1 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
       61 tattggaagg aaagtggtga tgagtgtcac aggtatcgcc cttgtcctgt ttctgacgtt
      121 tcacatggcg atgaaccttg ttgcgctctt ctcggaagat gcttacaaca tgatttgtga
      181 attcttggga gctaactggt acgcgttggt tgcaactgcc ggactggctg ctctgttcgt
      241 aatccacatc atctacgctt tctggttgac catgcagaac cgtgcagctc gtggtagcga
      301 acgctatgca gtgaacgtta aacctaaaac tgtggaatgg gcatctcaga acatgcttgt
      361 cctgggtatt atcgtcattg ccggattggc tcttcacttt gccaatttct ggtacaaaat
      421 gcagtttgcc gaaatcatcg gtgttcatga tttaggtgcg ttcggcccta cagacggtgc
      481 cgcttacatc cgtgaaacat tcggatgccc tgtatttaca gtgctttacc tcatttggtt
      541 agcagcttta tggttccacc tgactcacgg attctggagt gctttgcaga cattgggctg
      601 gagcaacaaa atctggttcg agcgttggaa gactattggt aacatctact ctactttggt
      661 agttcttggt tttgcagcag tagtcgttat ctacttcgta aaatcactcg cttgtggtgc
      721 ttgctaatcg taaattgtaa atgataaaat tgtaaatgaa tatggctact atagattcta
      781 aaattcctga aggcgcttta gccgagaaat ggaccaatta taaagctcat caaaaattgg
      841 taaaccctgc caacaaacgt cgtcttgaca ttattgtggt aggtaccggt ttggcaggtg
      901 cttcggctgc tgcttcactg ggtgctctgg gtttcaaggt attaaacttc tgtatccagg
      961 actctccccg tcgtgcacac tccatcgctg cacagggagg tatcaatgct gctaagaatt
     1021 atcaaaatga tggtgactcc gtttaccgtc ttttctacga tacaattaaa ggtggtgact
     1081 atcgtgcacg cgaagctaac gtttaccgtc tggccgaagt gtcaaatgct attatcgacc
     1141 agtgcgtagc tcaaggtgtt cctttcgctc gcgaatacgg tggtttgctt gacaaccgtt
     1201 cattcggtgg tgctcaggta tcacgtacat tctatgcccg cggccaaacc ggacagcagt
     1261 tgttgctggg tgcttattct gcattgagcc gtgaagttca gcgtggtaac gtgaaattgt
     1321 acactcgtta tgaaatgttg gacgttgtgc tgattaagga taacgaaggt gtggaacgcg
     1381 cccgtggtat catcgctcgt aacttggtta caggtaagat cgaacgtttt gctgctcatg
     1441 cagtagtaat cggtaccggt ggttatggta atacttattt cttgtctacc aacgctatgg
     1501 cgtcaaatgg atcggctgct atgcaggttt accgcaaagg tgcttatttt gctaatcctt
     1561 gttttgcaca gattcacccg acctgtattc ctgtacacgg tgacaagcag tctaaactga
     1621 ctttgatgtc tgagtcattg cgtaatgacg gacgtatctg ggttccgaaa aagctggaag
     1681 atgccaaggc attgcaagca ggaactaaaa aaccgactga tatacctgat gcagaccgtg
     1741 acttctatct ggaacgtcgt tatccggcat tcggtaactt ggttcctcgt gacgttgctt
     1801 cacgtgctgc gaaagaacgt tgcgacgcag gtttcggtgt gaacaacaca ggtttggctg
     1861 tattcctcga ctttaagtac gctatcgatc gtctgggtga agatgtagtt cgtgcccgtt
     1921 acggtaactt gttcgatatg tacgaagaaa tcactgacga gaacccatac aagactccga
     1981 tgatgatctt cccggctatc cactatacaa tgggtggtat ctgggttgac tatgaactga
     2041 tgacttctat caagggtctg tatgctatcg gtgaagctaa cttctctgac cacggtgcaa
     2101 accgtttggg tgcatctgca ttgatgcagg gattggctga cggttacttc gtattgcctt
     2161 acactatcca gaactatttg tcagaccaga ttcaggttcc ccgtttctca acagaccttc
     2221 ccgaattcgt agctgccgaa aaggctgtaa acgataagat ccagagactg atgaatatca
     2281 agggtcatcg ttctgtagac tctattcaca aggagctggg tcacatcatg tgggactttg
     2341 taggtatggg acgtaccaag gaatctttga ctactgctct ggctaaactg aaagaagtaa
     2401 gaaagacctt ctggagcgac cttcgcattc cgggtgaagc taatgaattg aatgtagaac
     2461 ttgaaaaggc aatccgcctg gctgatttca tcgaaatcgg tgagctgatg gcttacgatg
     2521 cattgaaccg tgaggaatct tgtggtggtc acttccgtga agaacaccag actccggaag
     2581 gtgaagcact tcgtcacgat gacaagttct cgtatgtagc ttgctggaaa tacaccggtg
     2641 aaggaaaaga acccgaattg atcaaggaag atttgaacta tcagttcgtt aaggttcaaa
     2701 ctcgtaacta taagtcttaa ttattaattg tatagaaatc atggataaaa atataagttt
     2761 cacactgaaa gtttggcgtc agaaaggtcc taaagacaaa ggacattttg ataccttcca
     2821 aatgaaagat attccgggtg atacctcatt cctggaaatg atggacatct tgaacgagca
     2881 gcttatcaat gaaggtaaag aacctatcgt attcgaccac gactgtcgcg aaggtatttg
     2941 cggtatgtgc tctatgtata tcaacggaca tcctcacgga cctgctacag gtgctactac
     3001 ctgccagatt tatatgcgtc gtttcaaaga cggtgacacc attactgttg agccttggcg
     3061 ttctgccggt ttcccggtaa tccgcgactt gatggtagac cgtagcgcat acgacaaaat
     3121 tatgcaggcc ggtggttacg tgtcaatcaa taccggtggt attcctgacg ctaacgcaat
     3181 tcctattgca aaacctattg ctgacgaggc tatggatgct gctgcatgta tcggttgtgg
     3241 tgcttgtgtt gctgcatgta agaatggttc tgccatgttg tttgtttctg caaaggtcag
     3301 ccagttggca ctgttacctc agggtaaagt ggaagctgca cgccgtgcga aagctatgtt
     3361 gagcaagatg gatgaactgg gctttggtaa ctgtacaaac actcgtgctt gtgaggcaga
     3421 atgtccgaag ttggtttcta tcagcaacat cgctcgtttg aaccgtgaat ttattgctgc
     3481 gaagctgaaa gactaatcac ggttagtttt acttgatatt tgagaatgcc ctgcctttgg
     3541 tggggcattt tttttgcctg gggcttcttc tttttctctc ttacgtatgt ttctgggaga
     3601 atcgccaaag aacttcttac agaagttgga gaaatgtgag agagattcga atccatgttc
     3661 gaagcagatt tcggagatgg aagcctctgt atagcgcaat tggtagagga tactttcttt
     3721 gcgctgcttc atcatccatt cataggccgg ttcgttgaag atagccttga aaatacggcg
     3781 gaaggtggtg acgctatagc cgcccagttg tgcgaagtct tctacagact ttatttgctt
     3841 gtggtgtttt aatataaaat attcaaagct gttggtatac ttggacaaac tgtgtacaat
     3901 gggggaaagc tcatagtctg tatagtagtg cgccagtaga taatacagtt ctttacgctt
     3961 gaattcaagc agttctttac agattttgtc tatattcaga taggaggtaa ctccttcaag
     4021 gaaaagcttt atttcgggct ttattttaag tggctcggag atgagtggcg ggggcacgtt
     4081 tttcaatata taggtatagc ggtcataaca gaaagctttg gggtcatcga atgtgtacag
     4141 aataccttcc gagtctgtca tggccagtat ttccactttt gatgcgatag cttgcagtac
     4201 aaattctccg ggattgatga tagtaccggc atattcttca ctattgatga gtatttggcc
     4261 tttgagtaag aaaaataaga tattagtttc acacttatgt gggggtaagt ggaaaccttt
     4321 tttgttatgt gtgtaatgga tgctattctc cactgcttta gggcattggg tacaatccat
     4381 cctttcatta cagggcagac cagacatata tagatgttag agacgcttgt gttctttttt
     4441 ttgatttgac aaatgtaggt caaatatgga taatttgcaa taagtttcaa gaaaaagacc
     4501 gaagaatcct gtttccactt gtttgtcttc tgccgttacg gaaaacgata gcctgtgggc
     4561 atgagcatag agggctaaat ttgtgtggcc aaacaaaaag aagttgcaat tgttgggaaa
     4621 gtagcagaaa gaaagtatct ttgtgtgtac cccatgggga ggtataccgg ctaaaacagc
     4681 atagattatg gaatttgtag tatcatcaga taagaaatta ttgccctacg gcatgatgaa
     4741 tttcgcggat atacgccttg atggttatta ttatgtggac aagaccatgt atatcccgtt
     4801 gatagaacgc tccaaccgtt attttttctt tatccgtccg cgtcgtttcg gcaaaagtct
     4861 gacgctgaat atgctgtaac attactatga tgtacgaacc aaggataaat tcgacgccct
     4921 gtttggagac ctctacatag ggaagtatct tacacgtgac cggaacagct acttggtatt
     4981 gtatctcaat ttctccggta tcattggcga actgcataac tatcgtgccg gattggacgc
     5041 acattgccaa acctgtttcg actatttctg tgatatttat gcggaatacc tgccgcaggg
     5101 tatcaaagaa cagttggacg caaagaatgg ggcggtagaa caattagact atctttatca
     5161 tgagtgtgag cgtgtcggtc aggatattta tctttttatc gatgagtatg accattttac
     5221 caatgccatc ctttcggatg ccgaaagcct gcaccgatat acgaaggaaa cgcacaagga
     5281 aggatatctg cgtgcattct tcaacaagat aaaatccggt acctattcca gcatcaaacg
     5341 ctgtttcatt accggagtca gtcctgtgac gatggatgtg gttgtttcta ggggtatttt
     5401 atgattgagg acggctgatt gtcaacaggt aaaaatgctc cgcaaatgaa atcgcaaatg
     5461 atagagggga tgatgcggtg tttcattgcg gagcggggaa ttgttatgtt tatctgtatg
     5521 tttgtcgggg gatttgtaaa ttcattaatt tatagtttgt tggtttctta taatacagga
     5581 gttttaggag tttgctcgtt atcagtggca ttccaatctt catcatatgt tgtgtttaca
     5641 ctcatttttt ctgcaccaac cggtaaagtt agtatatagc ggatactttg cccattagtc
     5701 cattctcctg ttaaagctac ttcttttgat ccgttaaaga atgttgcatt atctttctct
     5761 gttttatact tgactgtaat tttagcatca gtaagagatt gtgggtacag cattaatgaa
     5821 ttattatttt gtgtataatc ataaatatca tctttggctg ttacggtgtt atcaaatgta
     5881 tagctataac cactagcagg tgcacttcct gtgatattcc aatttccacc ttttccttca
     5941 gttcctccga atgtgtacgt tgcggcacca ccttttgcac cggtgatagt tatgctttca
     6001 actgtgtaag tatagttgct gtcagctagt tttgcagcaa agtttatacg ggttaagatg
     6061 tgttggaatg taaggtttaa tgtattatca cttggcttag ttatatcttt ggaataagct
     6121 actataatat ctttctgatc ggccggggta tcaggaaggg tatagctgat ggtgggataa
     6181 gcgctggaac tagcaggtgc tgtataggtt acatcattgg tatatccaaa aaattgcatt
     6241 tctgttatag gccaataaaa agtaccactt gttgtagccc aattaccttg acctccttta
     6301 tattctatgc catccatata cgcgttaccc catcctgaag tggcgatatc gctgctttta
     6361 attatatagg catgtaattt aaaagacgtg aaactactat tacttgtaac agtggccctt
     6421 gaactctttt tgacaatcgt gtttactcct atctcatttt tacttttggg agttccattg
     6481 tcaataccat caatctcatt ctgtgagcaa cttgtgattg ccaatgcagc taaagctgca
     6541 aataaaatct tcttcatatc ctatgtgttt taagttaata attctatgac tctttattct
     6601 atattttaac cgaccggtaa ttctacattc gtttcatcat cccagtcact gacgttccca
     6661 tcaaatccac cgccactttc atcaggagga atctctacat catccaccac aatcttctca
     6721 tcatccggaa gttcgatctc tatctccggc tcttgaggtt tttcatcgcc ttctcccggc
     6781 tcgtctttat cttcaggagg ttttaccgct tccgttattt ctactttcgc ttcctgtttg
     6841 gaaccatcca cttttactat aatcaagttc agaaactgag tgatatcggc tcttgcttgc
     6901 gtcagtttgg gatgcccaaa gcaggtaaaa ctccctttta tagccccatt ccctttactg
     6961 gtttcacaat aaataggagc gaaccggcat aggctggctc ctttgcccag gtggtaacat
     7021 tcagccattc cggaaacact gcccaggatg gatgcaacat ttttcagccc ttctgtcttt
     7081 attgaaaaag tgtaagtggt taccacagat tttggtttta cctctagtgt cggtaattct
     7141 tcctcttttc ctatctctac atcgtccagg gttgctacat aaaaattatc cggtccccat
     7201 accatgtctt tcgtttcctc ggcacccagt cccgtacagt ttcctgtaca tgccattatt
     7261 gtttcgtagc taccttcgtc ttttatttgc actacttcgg tgtcataatt gtaaatcact
     7321 gccgaataat gtcccggagg tacttttatt tctccgcctt tcgccggtaa gtaggtatca
     7381 atcttccttc cttggccgtc cttgggatag aagatgatcc ggactccttc cggcagacgg
     7441 tcggttactc cttcccaatt tagacggatg tttattcctg ttacggggta atcgtccaga
     7501 atctcgcggc ggctgcatcc cactaaagtc aatagtgaag ataaaagtac aagaattgcg
     7561 taccttgtct ttttcatttt cttcctcttt tcttggttat caaccatacc aacgaaattt
     7621 ttgctttcgt agggcctata aaggtgtaat ttccgctact catccagact agtgatccct
     7681 catagggagt atatttttga tattccgtgg tcagatagcc tatgcctagg ctgaattcca
     7741 atgccagatg tcgtgacaac aaagtggaat atccataagt gaatcctgcc gcaccgtaat
     7801 atttaccttg gtagccgttt cctttaaact gaaagtcgta gatacctccc tcgatataca
     7861 atccaaagaa atgtccgttc aatcggttgt gtagttcacg gttgcccagc cagtaacggc
     7921 tttctattcc tcccgaaatc agttggtagc agatttcttt actgctgttg gaccaccagg
     7981 ggcttttata ttccatattc actgaccatc tctttcctac aggaatttct atttctatat
     8041 taggtgccag tgccagatcg tacaataaat tatttttcag cgcaagcact gtgttgtcga
     8101 ctgtctggac tcttcttgct gccttttctt tgggcttttc tccccgtttc tcttttgtct
     8161 cttttttctt ttctgccttt attactgttt tttctgtttc tattattact tgtgttcttt
     8221 ccttctgtgg aagtacttgc atcgtcattg gcgtaacggt cgtttccctg tcaatcggta
     8281 tgaattcagt ttcttctatc cttgctgcct gttctgcgga ggagtttttt cctccgtttt
     8341 cttccggata agacaggcag actcttatct ctgtccgtct gagttccggt agcactcggt
     8401 cagaaatata ctgataaggt atgccggcgt ccaggcgttg caagaaatct tgcattttta
     8461 cgggattgtt atggtgataa tctatcaatg ccaatacatc ttcccggtcg gggaccagtc
     8521 tgtcgtccag tatcagtttc cgtaaggcat ccccgtactc ttctcctttg cggatacaga
     8581 tttgggcggt attgacctgc ggatatttcc cacataagaa cacttttact tcctcacttc
     8641 ttttttgtcc cagcggtatg ccctgttctt ttttaccatt atataaatcc ggtgaaacca
     8701 gaataatgga attaagatgg atgctgtggg caggattggc aagtagagaa tccaataccg
     8761 tcagcgtttt accgtttcct tggtaatcct tgtctatctg tcgggcattc aggtcaaaat
     8821 agagcgtcat gtccaacgtg gtgtctttgg gggtttcgta ctctattgtc cgggcataaa
     8881 tgctatttgg cagtaggcac aaaagcacaa atatgctgaa tatagtagtg cgttttttca
     8941 tgaattacca ttatgtatga agcaaatata ggtgataaaa tctgaaaaaa gacttattaa
     9001 atgttctatt ttcggacttg aaagggtttg tgaagcgatt ggatagaatt tgcaagtttt
     9061 ggcggttgga taatgagaag ggcaggggac ttacttttat tttggatgaa taacatgagg
     9121 gaatactttc tttttgtttt ttactttcca gcagacagga atgaatcatt ctatgatatt
     9181 gatagaataa tgtttcatat tcctttttta accccgcttt tcttgtcgga ttgtaatact
     9241 gtgtgcgaaa acgattgtat ttgtgaaata atactaaatg aaaagcaaaa atgaaccaaa
     9301 tatttggagg tattgagtgt aagttgtaca tttgtcatgt gatttttttc atagtattag
     9361 atttaaggtt aacaaaggtt ggagcaaggc gttgctcctt tcttttttta gtaccttctg
     9421 tttctttcca ttctcctaat catcagctcc ttaatgccgt tgatttttta aaatattctg
     9481 tttcttgttt tcatccaatg gattttatgt tatctttgtg tcaatgtaaa ctaactaaca
     9541 atctacatga aaagacacac aaacctttta tgcttggggg ctgctgtcgc attgctgaat
     9601 gcttgcgccc cggtggtgaa cgctcctgag cctgttcttc ctgttcccga gaaaaagcag
     9661 gtggactggc agaaaatgga aacttatgct ttcgtgcatt tcggactgaa tacttttaat
     9721 gaccgcgaat ggggttacgg agattctgac cctgccacgt ttaatccggt taaactggac
     9781 tgcgagcaat gggtgaaaac ttttgtggcg gcagggatga aaggagttat ccttacggca
     9841 aaacaccatg acgggttttg tctgtggcct acggggctga ccgaatattg tatccgtaac
     9901 acaccttata aggatggaaa aggagatatc gtacgtgacc tttcggaggc ttgtaaaaag
     9961 tatggtataa aattcgctgt ctatctctca ccgtgggaca ggcatcaggc caattatgga
    10021 actccggaat atgtggatta tttctatcaa cagttacacg aattgctgac ccattacggt
    10081 ccggtgttcg aaatttggtt tgatggagct aatggagggg atggctggta tggcggagcc
    10141 aaagactccc gtaccataga ccggaaaaat tattatgatt atgcgcgtgc atacgagatg
    10201 atcgacaaat atcagccgca ggccgttgtc ttctcgaatg gcggacccgg atgccgttgg
    10261 gtaggtaacg agaatggctt tgccggagct acaaactggt cttttctgcg tgctggagag
    10321 gtttatccgg gatatcctaa atacagggaa ctgcaatacg gtcatgcaga cggcaatcag
    10381 tggacggctg ccgagtgtga tgtgtctatc cgtccgggct ggttttatca tccggaggaa
    10441 gatgacaggg tgaagacggt ggagcaattg acagaccttt attaccgcag tgtggggcac
    10501 aatgcgactt tgttgctcaa tttccctgta aaccgggatg ggctgattca tccggtagat
    10561 tcggcgaatg cggttgactt ttataagaat gttcagaaac agctggcaaa caatctgttg
    10621 aaaggtgttc ttccgatagt ttccaatgaa cggggtggaa aatatactgc aaaggcggtg
    10681 acggatggag aatatgatac atattgggct acggaggata gtgtcacatc ggctgtcatc
    10741 gagtttgaat ggccggctcc gcaaaaggtg aaccgtatgc tgttgcagga atatattccg
    10801 ttggggcagc gtgtacaatc ctttgtggtg gaatataata aagaagggga gtggctgcct
    10861 gtgaagctga atgaagagac aaccacaatc ggttataaac gtttgcttcg ttttgaaaca
    10921 gtcactacgg acaaacttcg tataaatttt acggaatcac gtgcttgctt gtgtatcaat
    10981 aatatagagg cttattatgc aggagaaacc ccggatgtgt ttactgcgaa agcggaagaa
    11041 ctgaaaacgt atccgtttac attgccgcag gtagatgagg cggaagccgg aaaatgtgcg
    11101 gataaagatg ccgccacgac ttgctttgtg gatggcaata cgcttttgat agatttaggt
    11161 acggaacaga ctgtttcttc cttccattat ttacccgacc agagcgagta taacaaagga
    11221 ctgatagctg cttatgagat ttcagtgggc acggaggcca atgctgtgaa tcaggtggtg
    11281 agcagcgggg aattctcgaa tatcaagaat aatccgattc tccaatcggt ttatttcact
    11341 ccggtaacgg ctagatatgt attgctgaaa gcagtgagga tggtggaaaa cgagagtccg
    11401 atgggctttg ccgaattagg agtgcaatga ccatgtatca atatactcat gtgtccgttc
    11461 acaatacagc taccgtatgt caatgagtac atgagtatat tgatacatgg ttacattatt
    11521 aatcggtaca ctcctcctgc cagtgctcgt atcacccctt tcatttctaa ttcaaacagt
    11581 aatgcactca ttcggtttac aggtatgttg gtgtctatca ccaatgtgtt gatttgtaat
    11641 ccttccggca ttttgccgag tcgttttact attcgttctt cttcctcgct taaatcaggg
    11701 aacaattccc gttgtactgt tttctcagtt ttggggctgc tttcccatcc catacccttc
    11761 actaaatcct cggccgatgt gataagcact gcctggtttt tccttatcag attgttgcag
    11821 cctatggaat attcatcatt gcatcgtccc ggaaaggcaa aacagtcccg gtgataactt
    11881 tccgccagtt cggcggtgat gagggctccc cctttggcgg cggactcgat aacgacggtg
    11941 gcgtcactca tacctgctac aatgcggttt cgtttcacga aattttgcct gtcgggattg
    12001 gttccgcttg taaattcggt cagtaaccct ccctgttcca acatgctgac ggctgtcttc
    12061 cgatgttcgg caggataaat acggtccagt ccgtgtgcca gcacgcctat ggtcttgaaa
    12121 tgattctgca gggcggcgcg atgcgcatgg atatcaatgc cataagccag cccgctcact
    12181 atcaaggtgt ccggacacag tgccgacagg tcggcaagga aacgggtgca gatatcctgc
    12241 ccgtaggggg tggcatgacg ggttcctact atattaataa tatgcagcgt gttcagatcg
    12301 gcatttcccc gataaaataa agctagcgga gcatcatcac attcacgcaa acggctggga
    12361 taaccttcat catttaaggt gaggcagcgg atatgatttt tctgacagaa agttaattcc
    12421 tgctctgcac gccggaaagc ttcggagtta ttcaacgcag taatgatctt ttcgcttact
    12481 ccggggacca attgtgacag ctctttgcgg tgttcgaaaa cacgggtggc gcttcccaga
    12541 ctgctcacca gtctgaatgc gcctgtcagt cccaatcccg gtatccgggt tagggccagg
    12601 ctgcaaattt gttcgtcttg tgtcattcgc tcaggtaggg tgcgaaagtc tcgtcaaata
    12661 gagcgctgtc ccctaatctg ccgtttacca cgcatactga ttctacagtg gccttgacag
    12721 tcactttcat atcgggcaga cggaagatgt cctgatagaa cacatattta ataccttctt
    12781 ttttcagata gagtttagaa acgaattcgt caccgctgcg cagcggagtt ttgaacgcca
    12841 tggtgagccg tgccactacc gggtctactc cttcctcgtg caaacgcgcg aagctgatac
    12901 ctatggatgt gagaaactca tggcgtgtat gttccagata atgctgataa ttggcgttgt
    12961 ttacaatgcc ttgcaggtcg cattcataat cgcgtacctt catcttcagt tcataaatat
    13021 acttttccat aaagcaaagg tataagaaaa atgtgttact ttgcatctaa actaaaaaaa
    13081 agaagtgaat gaaactatat gctgcgcctt tacaaggttt tacggaagct ccctggagaa
    13141 actttcatga ggaagttttt ggtggaatag atgcgtatta tactcctttt gtacgaatag
    13201 agagaggagg attccgtaac agggatgtac gggacattgc tcccgaaaac aatacggttt
    13261 cccgtgtagt gcctcagctc atcgcgtcca ctcctgtcga gctggaacgg ttggccgctt
    13321 tgtttacaga gaaaggatat aaggaagcgg attttaatat ggggtgtcct tttccgctgg
    13381 ttgcaagaaa gcacaagggc tccggcatat tgccttatcc tgccgaggta gaagctttat
    13441 tgaaagagtt gacacattat cctgaactga gtttttcggt taagatgaga ttggga
//
