LOCUS       c00037_gnlPro..        16973 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOLHMPCE_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:38:15
            Original ID  :: gnl|Prokka|NOLHMPCE_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 138483
            Orig. end    :: 155456
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16973
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[148483:151442]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12959
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16973
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16973
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             380..1180
                     /locus_tag="ctg37_116"
                     /transl_table=11
                     /translation="MKKRIVFIAALLCGMCFTTASAQFKIGGKKINVGKVVQAGSDAAK
                     AITLSDSDIAAMSKEYMQWMDTHNPLTAADSEYGKRLEKLTGHIKEVDGLKVNFGVYEV
                     VDVNAFACGDGSVRICAGLMDIMTDDEVMAVVGHEIGHVIHTDSKDAMKSAYLRSAVKN
                     AAGAASSTVSKLTDSELGAMAEALAGAQYSQKQESEADDYGFEFSIKHNIDPYAMYNAL
                     NKLLELSAEAPKESKFQKMFSSHPDTAKRVARAKEKADNYTKNK"
     CDS             1337..2626
                     /locus_tag="ctg37_117"
                     /transl_table=11
                     /translation="MEFLVIILLLVLNGIFAMYEIALVSSSKARLETLVSKGNKSARGV
                     LKQLEEPEKFLSTIQIGITLIGIVSGAFGGVAIADDVTPLFAMIPGAEVYAKDLAMITT
                     VIVITYLSLIIGELVPKSIALSNPERYATLLSPVMILLTKISFPFVWLLSISTRLLNKL
                     IGLKSEERLMTQEELKMILHQSSEQGVIDKEETEMLRDVFRFSDKRANELMTHRRDLVV
                     LHTTDSKEKVLQIIDNEHFSKYLLIDDDTDEIAGVVSVKDIILMIGSEQEFNLREIARP
                     ALFIPESLYAKKVLELFKKNKNKFGVVVNEYGSTEGIITLHDLTESIFGDILEEDDTEE
                     EEIVRRQDGSLLVEASMNIGDFMEEMGILSYDDIESEDFTTLGGLAMFLIGRIPKAGDI
                     FTYKNLQFEVVDMDRGRVDKLLVIKREEEE"
     CDS             2678..3136
                     /locus_tag="ctg37_118"
                     /transl_table=11
                     /translation="MLAAVVAALVSCQSKGTKAEEAVADSLAVAMEPTMEETQVYEGVL
                     PAADGPGIRYVLTLNTLANATDTTYTLDVTYLDAEGKGKDKTFTSKGKPVKVEKTVKDK
                     KKTAIKLNPSDGSEPVYFVIANDTTLTLADDSLEVSESDLNYNIIRVK"
     CDS             complement(3222..4811)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Melibiase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_119"
                     /sec_met_domain="Melibiase (E-value: 2.4e-07, bitscore:
                     23.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRKATLLFLVTFVLLLGAVAQEKLKTVIEPLQNERWWGGFVALG
                     NQMPFNDHLRMQDMSRNNMNNQVVPFMLSSEGRYIWAENPFCFEVKDGQLIIYSDSEKI
                     EPVKAGTTLKEALLAASAKHFPPSGKIPEPTFFSLPQYNTWIELMYDQNQEDIMNYAHK
                     AVENGFPQGVFMVDDNWQRYYGNFDFKTERFPDPKGMTDELHRMGFKVMLWVAPYVSPD
                     SPEFRELEAKGYLLKDKNGRTAIIHWWNGYSACYDTTNPEAMNYLKEQLKANQEKYGID
                     GFKFDGGDVAYMTGEYTFHDKNANVNTFMEKWAEIGLSFPYNELRASWKLGGQALVQRL
                     GDKDYSWRATQLLIPDMTAAGLLGHYYTCPDMVGGGQFGAFLNVKKFDEELIVRSCQVH
                     ALMPMMQFSVAPWRILSKENVAICAKYAHLHQQMGDYILELAKHASKTGEPIVRHMEYQ
                     YPHQGFIDCKDQFMLGDKYLVAPMLTSGTSRTVMLPKGRWKDDRGKVFKGPRTMTIDVP
                     LERLPYFEKLTK"
     CDS             5192..5590
                     /locus_tag="ctg37_120"
                     /transl_table=11
                     /translation="MEQTFKARNPQLGVWLFAIGIIACIAISFITIQAIWIGTACIGPS
                     ATIYFSQTSCKYIVKKNGDLQIVNDFFRQKRTFSHITDVTYTRHALGMQKIKIRHATGF
                     VMIDPQSPRELIKALQKTNPDVRVKNFI"
     CDS             5642..8215
                     /locus_tag="ctg37_121"
                     /transl_table=11
                     /translation="MKTPKTLKVHLLLYLFCLSVSAQTTDSIVQKLSQYAYLIDNFSKY
                     IPQEKVYMQFDNTSYYQGDNIWFKCFLVTSDLHPATDLSKTLYVELLNPGGEVIDKRTL
                     KIENGQCHGDFTLGQLPFYSGFYEIRAYTKYMLNFGGDIIFSRLLPVFDKPKAEGDFTE
                     KEMRKYATGNYPLERPKPTKGKKVNLKFFPEGGNLVRGIESEVAFEATDTYGNPITLTG
                     IVINEEKQETARFNVTHDGRGIFNYTPTGEKQKAIVEFNGKKHQFNMPEALPEGYTLHA
                     DNLSFTDSIEIAVQKNSNTPSGVLGLAVISGGKLYKFCLIDVEGNETIRFKIDKSKLVP
                     GVSRIALFNSNGEVLSDRLIFTYPQEQLSVQVQADKETYAPYELVNLEFTLTGKEKIPV
                     QTPFALSVRDGMNEVESGHNMLTDLLLMSEIKGYVNNPQYYFESRDDTRRKAIDLLLRV
                     QGWRRYSWKQMTGIESLDLKYGPEQGIETRGQVVSFVRQLPKPNVEVSCFLKKRGENEE
                     NSSFIEAITTDSLGHFSLISDIYGKWDLILAVTVNRKKKDYRILLDRLFSPAPRKYHYA
                     DMQVSIANAEKEKELMPEVETTPLPEEDIETFFAAYADSLAKAGNHEKNYRLKEVTIKA
                     KKRTKEKEIYESRSKSIAYYDVHSELDDIKDSGKFIGDDIHELMMNMNKNFSPVSGRNY
                     LYYKSKMPLFVINYERTRHTEMDYNKYKYIRLEAIKSIYITENLSTICQYADPRLTPFD
                     VSDLYSCAVLIETYPEGKIPTEAGKGVRKTWLDGYSQVKEFYHPNYSVLPPVPDYRRTL
                     YWNPSVTPDKEGKAHIRFYNNSRCRKLKISAETITTNGLIGTYGN"
     CDS             complement(8400..8867)
                     /locus_tag="ctg37_122"
                     /transl_table=11
                     /translation="MAKELNFTLEGVQGDLKLKYGPFNQRLYQDGREIKKQGRFNPKYY
                     VINTNGEKEEIKVVYGFDFVHVAVFRGQKIDLEERLSIREYIVGGLPVLLVFLGGLIGA
                     LFGIMGATFNYNHMRQEKSFIKQLLVSLGVSILCYVAYFIFAIGVQLIVAR"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_123"
                     /sec_met_domain="Gly_radical (E-value: 4.5e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1164.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVETDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12234..12959
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_124"
                     /sec_met_domain="Radical_SAM (E-value: 6.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(13192..14454)
                     /locus_tag="ctg37_125"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKQPEAVTEEKRAEPQQEATAAIE
                     KKESVTAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGVVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(14506..15054)
                     /locus_tag="ctg37_126"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             15242..15994
                     /locus_tag="ctg37_127"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(16219..16971)
                     /locus_tag="ctg37_128"
                     /transl_table=11
                     /translation="AFCGGAAVLFAKRPADGEVINDISMDITNFYWMAKVYYRDLKQEI
                     EKTLHSRDMHAHAGHILQYPQFFQPVQRAWAVWALCKMSFASMMDGSFGYDFGGGMPKK
                     LRNAKDEFTEWLCSRLDNVTIENRDALDVISTYDSPDTFHFVDPPYINSDCGHYEGTFD
                     EYCMEKLLQLLEQVKGKFMLTMFPLPMIEEYANKNGWIIHRVERTISASKTSRRKQEEW
                     MVCNYEEHPQRTLFDYKDSNDANITDAS"
ORIGIN
        1 cttatgatgt ggaaaaatca tctcttgtta cggcatggaa tgcacaggga cgtccatact
       61 atgactacac aaagtacaat accggacgct tgcccgcctt cggccaactg gatgtacgag
      121 tggacaaaac attttatctg aaacgctgta tgttgggatt ctacatcgat ttgcagaatg
      181 tgacaaacag caaattcaag caaccggata tcctgatgag tacaggcgtt atcgaaaatc
      241 catccgcccc catggcagaa cagcgctaca aaatgaaata cataacccag aaaagcggaa
      301 cattaatgcc aaccttgggt atcacatttg aatattaaat ctcgaaacaa ctatattatt
      361 aactataaaa actcacaaaa tgaaaaaaag aattgttttt attgcggcac ttttatgcgg
      421 aatgtgcttc acgacagcat ccgcacagtt caaaatcggt ggaaagaaaa tcaatgtagg
      481 caaagtggta caagccggta gcgacgcagc gaaagccatc accttgtccg actcggacat
      541 cgcagccatg agcaaagaat acatgcaatg gatggacacc cacaatccgc tgaccgcagc
      601 cgacagcgaa tacggcaaac gcctggagaa actgaccgga catatcaaag aagtagacgg
      661 actgaaagtg aatttcggag tatatgaggt tgtcgacgtg aatgcttttg cctgtggtga
      721 cggcagtgtc cgcatctgtg ccggattgat ggatattatg acggacgatg aagtgatggc
      781 agttgtcgga catgagatcg gtcacgtgat tcatacagac tctaaagatg ccatgaagag
      841 tgcatatctt cgttcggcag taaagaatgc tgcaggagca gccagctcta ccgtttccaa
      901 actgactgat tcggaactgg gagctatggc agaagcatta gccggtgccc aatattctca
      961 gaagcaagag agcgaagccg atgattatgg tttcgaattc agcatcaaac ataacattga
     1021 tccgtatgca atgtacaatg ctctgaacaa actactggaa ctctcggccg aggctcccaa
     1081 agagtctaaa ttccagaaaa tgttctcttc acaccccgat acagccaaac gtgtagcacg
     1141 cgccaaagaa aaagcagaca actatactaa gaacaagtaa gttcgagaac cacaaaactg
     1201 agtttaaccg aggccggatc ccaatatatg aggtccggcc tcggtctttt tgaaaaaatt
     1261 cattaataat tccgatagtt tttgcgtgag tccgtacttt ggtgtaattt gcggtcatga
     1321 aactattcaa acttatatgg aattcttagt aattattctt ttactcgtac tgaatggcat
     1381 ttttgccatg tacgagattg ccttagtatc ctcaagtaaa gcacgtctgg aaaccctggt
     1441 cagcaaaggg aacaaatctg cccggggagt attgaaacaa ttggaagaac ccgaaaaatt
     1501 tctttctacc attcagattg gtatcacgct gatcggtatc gtatcgggtg ctttcggtgg
     1561 agtagccatt gccgatgatg tgactccgct ctttgccatg ataccgggag ccgaagtcta
     1621 tgcaaaggac ctggccatga tcacaaccgt aatcgtcatt acctacctgt cactgattat
     1681 cggtgagctt gtacccaaat ccatcgctct cagcaatccc gagcgctatg caaccttgct
     1741 gagtcccgtc atgattctgc tgaccaagat ttcattccct tttgtctggt tgctcagcat
     1801 ttccacccgc ctgctcaaca aactgatcgg tctgaaaagc gaagaacgcc tgatgactca
     1861 ggaagaactg aaaatgattc ttcaccaaag ctcggagcag ggtgtgattg acaaagaaga
     1921 aaccgaaatg ctacgtgatg tctttcgctt ttcggataaa cgtgccaacg aactgatgac
     1981 tcaccgacgt gatctggtgg tgctacatac gactgacagc aaagagaaag tgcttcagat
     2041 catcgacaac gagcatttca gtaaatacct cctgattgat gacgacaccg acgaaatagc
     2101 aggtgtggtt tctgtgaaag atatcatact gatgataggt agcgaacagg aattcaacct
     2161 tagagaaatc gcacgtcccg ccttgtttat acccgaaagt ttatacgcta aaaaagtttt
     2221 agagctattt aagaagaaca aaaataagtt cggagttgtt gtaaacgagt atggcagcac
     2281 agagggaatc attaccctgc atgacttgac cgaaagtatc tttggagaca ttctggaaga
     2341 ggacgatacg gaagaagagg aaatcgttcg ccgacaggac ggctccttgt tggtagaggc
     2401 ttcaatgaat atcggagatt ttatggaaga gatgggaata ctctcttatg atgatatcga
     2461 atcggaagac tttacaactt taggcggatt ggctatgttc ctgataggac gtattcccaa
     2521 agctggagat atattcactt acaaaaacct tcagttcgaa gtagtggata tggaccgtgg
     2581 aagagtcgat aagctgttgg ttattaagag agaagaggag gaatagcaac tcacttttta
     2641 tattaattta aagcacttaa caatgaaaaa agtaattatg ttagcagccg tcgttgctgc
     2701 attggtatcc tgccaatcaa aaggaacgaa agctgaagaa gcagtcgcag acagtctggc
     2761 agtagctatg gaacccacaa tggaagaaac ccaggtatat gaaggtgtgc ttcctgctgc
     2821 tgacggtccg ggcatccgtt acgtgttaac tttgaacaca ctggcgaacg caaccgatac
     2881 aacgtataca ctggacgtca cttatctgga tgctgaaggt aaaggcaaag acaagacttt
     2941 tacttctaaa ggaaagccgg taaaagtgga gaaaaccgtc aaagataaaa agaaaacggc
     3001 catcaaactg aatccgagtg acggaagtga acctgtttat ttcgtaattg ccaatgatac
     3061 taccctgaca ctggctgatg acagcctgga agtatcggaa agcgatctga attacaacat
     3121 tatccgtgta aagtaacgcc gaattagctt aaacttacaa aaacaaaagc cacgctgtac
     3181 atattgacag tgtggctttt cttgttttat cggcccagaa attatttcgt cagtttctca
     3241 aaatatggca aacgttcaag gggaacatct attgtcattg tccgcggccc tttaaacacc
     3301 ttgccccgat catctttcca tctacccttt ggcaacatta cggtacggct tgttccggat
     3361 gtcagcatcg gagctaccag atatttatcc cccagcataa actggtcttt gcaatcgatg
     3421 aatccctggt gaggatactg atattccatg tggcgaacaa tgggttcacc ggtctttgac
     3481 gcatgttttg ccaactccaa aatataatct cccatttgct ggtgaagatg ggcatacttc
     3541 gcacaaatag ccacattctc tttactgaga atacgccaag gagctaccga gaattgcatc
     3601 attggcatca gggcatgcac ctggcacgaa cgtacaataa gttcttcatc aaatttcttc
     3661 acattcagaa aagctccgaa ttgtcctccg cctaccatat cgggacaagt ataataatgc
     3721 cccaacaatc cggcagcagt catatcggga atcaataact gagtcgcacg ccaagaataa
     3781 tctttatcac ccagccgctg taccaatgcc tggccaccca acttccaaga tgcacgcaat
     3841 tcattgtaag gaaaactcaa acctatctca gcccattttt ccataaaagt attcacattg
     3901 gcattcttat catgaaaagt atactctcct gtcatataag ctacgtctcc accatcaaac
     3961 ttaaatccgt cgataccata tttttcttga ttggctttta actgttcctt cagataattc
     4021 atagcttccg gatttgtggt atcataacag gcactgtaac cattccacca atgaataatg
     4081 gccgtgcgcc cgtttttatc tttcaacaaa tatccttttg cttccaattc acggaattcg
     4141 ggactatcgg gcgaaacata gggagccacc cacaacatca ccttgaatcc catccggtgc
     4201 aactcgtctg tcatcccttt cggatccgga aacctctcgg ttttgaagtc aaagttacca
     4261 taatatctct gccagttatc atctaccata aacaccccct gaggaaatcc gttctccaca
     4321 gctttatggg cataattcat aatgtcttcc tgattttgat catacatcag ctcaatccag
     4381 gtattatatt gcggaagaga aaagaaagta ggttccggaa tctttcccga aggtggaaaa
     4441 tgtttagccg atgcagccag caaagcctct ttcagcgtag ttccggcctt caccggctct
     4501 atcttttccg agtctgaata aataatcagc tgcccatcct ttacttcaaa acaaaacgga
     4561 ttttcggccc agatatacct gccctccgaa gaaagcatga acggcactac ttggttgttc
     4621 atattattgc gtgacatgtc ttgcatccgc aagtgatcat tgaatggcat ttgatttcct
     4681 aaagccacga atccacccca ccatctttca ttttgcaggg gttcgatcac tgttttcaat
     4741 ttttcctgtg cgactgcacc gagcagcagc acgaatgtca cgagaaatag taaagtcgct
     4801 tttcgtttca tgatagttag attaataatt aaaattctca aggggcaaaa atagataaaa
     4861 aagaaagaac agatcatcta tcggcaaaga attattattt ccggaccgta gcttcccgca
     4921 taaaaacaga atctaaattt tccgattcca aattcttgtc cgaattttgc acattacaag
     4981 cacctgttca aatctccctt gcctattttt catcgaccgc agccacggtg gtttagagaa
     5041 gcttttatct ttttcactgg aactttcgga atccaacagg ccctaaataa ttattttcgc
     5101 agtcacaatt cagaaaagaa tagaaaaaag attctttcat tatatttttt tctatcttta
     5161 tcagacagtt acacatacaa tctaaaaaaa gatggaacaa acatttaaag cgcgaaatcc
     5221 ccaattagga gtttggttgt tcgccatagg tataatagca tgcattgcga tcagtttcat
     5281 aactatacaa gcaatctgga taggtaccgc atgtataggt cccagtgcaa ccatctattt
     5341 ttcacaaaca tcctgcaaat acattgtcaa gaaaaacgga gatttacaaa tagtaaatga
     5401 cttcttccgc caaaaacgaa cattcagtca tatcaccgat gttacgtata ctcgccatgc
     5461 cttgggcatg cagaaaataa agatcagaca cgccaccggg tttgtcatga tagatcccca
     5521 atcaccccgg gaactgataa aagccctgca aaagacgaat cctgatgtaa gagtaaagaa
     5581 ctttatttaa gacaggactc acaacggaaa aaccaatctc ccatctaacc caagatacga
     5641 aatgaaaaca cctaaaacat taaaggtaca tttgctatta tacctgtttt gcctgagtgt
     5701 atctgcacaa accacggaca gtattgtcca aaaactaagc caatacgcct acctgatcga
     5761 taatttttcc aaatatatcc ctcaagagaa ggtttacatg caatttgaca ataccagtta
     5821 ttaccaaggt gataatatct ggtttaaatg tttcctggtc acttccgacc tgcatccggc
     5881 cactgacctg agcaagactt tatatgtcga attattaaat cccggtggtg aagttatcga
     5941 caaacggaca ttaaaaatag aaaacggaca atgccacgga gatttcacac taggccaact
     6001 cccgttttat tcaggatttt atgaaattcg tgcctacaca aaatatatgc tgaattttgg
     6061 aggagatatc attttctcaa gactgttgcc ggttttcgac aaacctaagg cagaaggcga
     6121 ctttacggaa aaagagatgc ggaaatatgc gacaggaaac tacccgctgg agcgtcccaa
     6181 accgacaaaa ggtaaaaaag taaatttaaa gttcttcccc gaaggtggaa atctggttcg
     6241 ggggatagaa tccgaagtgg cttttgaagc gacagatacc tatggaaacc ccattaccct
     6301 caccggtatt gttattaacg aagaaaaaca agaaacagcc cgtttcaatg tcacacatga
     6361 tggacgggga attttcaatt acacgcccac gggagagaaa caaaaagcaa tagtcgaatt
     6421 taatggcaaa aaacaccagt tcaatatgcc ggaagcctta ccggaaggat atacattaca
     6481 tgccgacaat ttatcattca cagacagcat tgaaatagca gtgcaaaaga attccaatac
     6541 cccctccggc gtattgggac tggcagtcat cagcggaggc aaactataca aattctgcct
     6601 gatcgatgtc gaaggtaatg aaacgattcg cttcaaaata gataaaagta aattagtacc
     6661 cggagtttcc cgaatcgcgt tattcaacag taacggagag gtcctatcgg atcgtttgat
     6721 atttacctat ccccaagagc aattatccgt tcaggtacag gcagacaaag agacatacgc
     6781 cccttacgaa ttggtaaacc ttgaattcac cctgaccgga aaagaaaaga ttccggtaca
     6841 aactccattt gccctatctg tgagagacgg catgaatgaa gtagaatcag ggcacaatat
     6901 gttgaccgat cttttattaa tgtccgaaat aaaaggatat gtcaacaatc cccaatatta
     6961 tttcgaatcc cgggacgata cacgccgcaa ggcaatcgat ctcttattaa gagtgcaggg
     7021 atggcgccgc tactcttgga aacaaatgac aggaattgaa tctcttgacc ttaaatacgg
     7081 accggagcaa ggtatcgaaa cgcgagggca ggttgtctct ttcgtccggc aacttcctaa
     7141 gcctaacgta gaagtgtcct gcttcctgaa gaaacgcggg gagaatgagg aaaacagcag
     7201 tttcatcgaa gccatcacta cagatagttt aggacacttc tcactaatat ccgatatata
     7261 tggaaaatgg gacttgatat tggcagttac agtcaataga aaaaagaaag attaccgtat
     7321 tttattggat aggctattca gccctgcccc ccgaaaatat cattatgcgg atatgcaggt
     7381 aagcattgcc aatgcagaaa aagagaaaga acttatgccc gaagtggaaa ccactcccct
     7441 acctgaagag gatatcgaaa ccttctttgc cgcttacgca gattcgctgg caaaggcagg
     7501 taaccatgaa aagaactacc gtttaaaaga ggtaaccatc aaggccaaaa agagaaccaa
     7561 agaaaaagag atatatgaaa gccgttcgaa atcgattgct tattatgatg tacattccga
     7621 actagacgac ataaaagaca gtggaaaatt tattggtgac gacatacacg aacttatgat
     7681 gaacatgaat aaaaatttca gtcctgtttc aggacgaaat tacctgtatt ataaaagtaa
     7741 aatgccactt ttcgtaatca actatgaacg cacccggcat acagaaatgg attataataa
     7801 gtacaaatat ataagactcg aagccattaa atcgatttat atcactgaaa atctatctac
     7861 gatttgccag tatgcagatc cgcgattgac tccgttcgat gtatccgact tatacagttg
     7921 tgccgtactg atcgaaacat atccggaagg taagataccg acagaagcag ggaaaggtgt
     7981 ccgaaaaaca tggcttgacg gttacagcca agttaaagaa ttctatcacc ccaattattc
     8041 tgtgctccct cctgtccccg actatcgtcg tacattatac tggaatccgt ctgtcactcc
     8101 ggataaggag ggaaaagcac atatccggtt ctataataac agtagatgcc ggaaactgaa
     8161 aataagtgca gaaactatca caacgaatgg attaatcggt acctacggga attgataaaa
     8221 aacgggaatc tcccgaaaga atacagagaa aatacagttt tcatttttcc tttcgcctgt
     8281 tttacttttc ccaatatgga tagtcgccat catccatggg gaggacattc agaagtttac
     8341 taaaaaaggt ggcatacgga ataaccgtga agccaccttt cttttacttt ccagccagcc
     8401 tatctagcca ctatcaactg gacaccaata gcaaatataa aataagctac atagcagagt
     8461 atggaaacgc ccagggaaac aagcagttgt tttataaaag acttttcctg ccgcatatga
     8521 ttataattga acgtagcacc catgatgccg aacaaggctc caatcaatcc acctagaaag
     8581 acaagtaaca caggcagacc gcccactatg tattcgcgga tagatagccg ttcctccaga
     8641 tcgattttct gtccgcggaa cacagcgaca tggacaaaat caaaaccata gacaaccttt
     8701 atttcttctt tttccccatt ggtgttaatc acataatatt tcggattgaa tcgtccttgt
     8761 ttcttgatct ctcttccgtc ttggtataaa cgttgattaa aaggaccgta tttcaacttt
     8821 aaatcacctt gtacaccttc caatgtaaaa ttcaactctt ttgccatact atttatttta
     8881 gaattaagtc tatttacaaa gatagacaaa agctttgatt ttcatcattc ataaattatt
     8941 taatttgacg tgaatacgat ataattcatc aatctgttat cttaaaaaaa taggaataca
     9001 gcaataaaat catttaagtt agaatattta atcataagat ttaacaactt tccactatag
     9061 tcaccgaaga taaagttagt attcatttca tagccaacat gctatcagcc attaccgttt
     9121 attgtctctt taaaaaacaa ccagtcattg gtgtaaattt cacaaatgac ggcaactgaa
     9181 aatcttttaa ataatgtcga cctcaggtca attactgata tatagaaaaa agtaaaaaag
     9241 aatgtagtat aatgaattag aggatagcaa aacactgaaa taaaggaata gcccgactat
     9301 atatcttaca aaaggaatac aaaaaataga accttgcttt gattgataaa ctttgataat
     9361 gtgtgtcgct ccttaaaaag taacgttcaa gccaacggtc tatataagag gcctcaacta
     9421 ttgcatttac aactagacac ctataatgaa ggcggtgtgg taatgacatc tgctcaagta
     9481 gcggaacaaa taaaatcgat tttcccacta ttctacatac aaggtaggtc ctcaagggtt
     9541 atcattgatc tacgttgctc ctcgttcttt attatgcaga ctgatatgtt atatactaaa
     9601 aaaagaaagt ccttgaatta ttgaaattca aggacttata accttatttt tttgttttca
     9661 gcggagagac agggattcga accccgggta cctcgcagta caacggtttt caagaccgcc
     9721 gcaatcgacc actctgccac ctctccagaa ctacggttaa gtagtgcttt tctcttaaag
     9781 cgctgcaaag gtacgaatca ttttttaact tgcaaattat tccgcaaaaa aatattagaa
     9841 aagtatattt ggaagtaata actgctatct agcttctccc cataaatagg tatttttatg
     9901 ctattcaaca taaaatagga cccttttata tacctaaacc gaaaaaaggt tgtaaatttg
     9961 cgcgctctaa aggataacta accactaact gattaatttt atggaactga ataagacctt
    10021 taaagatgga ctttggagta aagaaatcaa tgtaagggat ttcgttagta acaacatcac
    10081 tccttatgaa ggggatgctt ctttcctgca aggacctacc gaacgcacca aagctgtctg
    10141 gaatcactgt ctcaaagctc tcgaagaaga gagaaacaat aatggtattc gtgcactcga
    10201 ctacacaact gtatctacta taacctctca ccctgccggc tacatcgata aagagaacga
    10261 actgatcgtc ggactacaga ccgatcaggt gttaaaacgt gccatcaaac cgtttggcgg
    10321 aatcaatgtg gttatgaaag cttgccgtga aaacggagtg gaagtagatg acagagttaa
    10381 ggatatcttc actcactatc gcaagactca caatgatggg gtattcgatg tgtataccga
    10441 agaaattcgt tcgttccgtt cattgggatt ccttaccgga cttcccgaca actatgcacg
    10501 cggacgtatc atcggtgatt atcgccgcct ggctctctat ggtcttgacc gtctgataga
    10561 agctaaaaaa gaagatctgc ataatctgac aggtcctatg actgaagccc gcattcgtct
    10621 tcgcgaagaa gtagccgagc aaatcaaggc cctgaaagag attaaagtat tgggcgaata
    10681 ttatggtttg gatctgagcc gaccggcata taccgcacag gaagctgtac aatgggtgta
    10741 tatggcttat ctggctgccg taaaagagca ggatggtgct gccatgtcac tgggtaatgt
    10801 atcttcattc ctcgacatct atcttgaata tgaattaagc cagggtacga taaccgaaac
    10861 attcgctcag gaactgatcg accaattcgt tatcaaactc cgtatggtac gccacttgcg
    10921 tatgcagtcg tacaacgata tttttgcggg tgatcccaca tgggtgaccg aatctatcgg
    10981 tggacgtttc aatgatggac gtaccaaagt tactaaaact tctttccgct tcttgcagac
    11041 actttataac ttaggcccgt caccggaacc taacatgact gtactatgga gccctgagtt
    11101 gcccgaaggt ttcaaagcat tctgtgcaca agtatctatc gacacttctt ccgtacaata
    11161 cgaaaacgac gacctgatgc gtgaagtccg tcaatcggat gactacggaa tcgcttgttg
    11221 tgtttcatat caggaaatcg gaaagcagat tcagttcttc ggcgcacgtg ccaaccttgc
    11281 caaagccctg ctactggcta tcaacggagg acgttgcgaa aatacaggta cagttatggt
    11341 aaaagacatc cctgtattga ccggtgaaac actgaagttc gaagaagtaa tggccaacta
    11401 taagaaagta ttgatacaaa ttgcacgtgt atacaacgaa gcaatgaata tcatacatta
    11461 catgcacgat aagtattact acgaaaaggc acagatggct ttcgtggaaa ctgatccccg
    11521 cattaacctc gcttatggtg tagccggact ttcaatcgcc atcgattcac tgtccgccat
    11581 caaatatgca catgtgaaag cccgtcgcaa cgacatcgga ctgacggagg gattcgatat
    11641 cgaaggtgct ttcccttgtt tcggtaatga cgatgaccgt gtagaccacc tgggtgtaga
    11701 cctggtatat ttctttagcg aagaattaaa gaaactcccc gtatataaga atgcccgtcc
    11761 taccctctcg ctgctgacta tcacttcgaa cgtaatgtat ggcaagaaga ccggtgccac
    11821 tcctgacgga cgcgccaaag gcattgcctt tgctcccggt gccaacccca tgcacggacg
    11881 tgataaaaat ggtgcaatcg cctcactgag ttctgtagcc aagttgcgtt atcgcgactc
    11941 acaggatggt atcagcaata cattctcgat cgttcccaaa tcattgggag caacacaaga
    12001 ggaccgtatc gacaatctgg tgaccatgat ggacggatat tttacaaaag gcgcacacca
    12061 cctgaacgta aacgtgctga accgggaaat gttgcaggat gcgatggaac atcccgaaaa
    12121 gtatccgcaa ctgactatcc gtgtctcagg atatgccgtt aatttcgtga aattgagccg
    12181 cgaacatcag ttggaagtaa tcagccgcag tttccacgaa agaatgtaat tgaatgataa
    12241 acgtacactc atacgagtca atgggaacat tcgacgggcc gggtctccgg ctcgtcgttt
    12301 tccttcaagg gtgtaacttc cgttgcctct attgtgccaa tccggacaca attgaagcca
    12361 aaggagggac agcaaccgat cctgaggaaa tagttcgcat ggccgtcagt cagaaagctt
    12421 tcttcggtaa aaagggaggt atcacctttt ccggcggaga gcctactttt caagcaaaat
    12481 cgcttatccc actttttaaa agactaaagg aagcaggaat ccatatttgc cttgatacca
    12541 atggcgggct atggaacaat gatgtagagg aactattgga attgactgat ctggttttat
    12601 tagatatcaa agaatttaat ccggaacatc atcagtcttt aaccggaaga agcaacgagc
    12661 agaccctgaa aaccgcagcc tggcttgaaa ccaatcataa accattctgg ttgcgatacg
    12721 tattagtgcc cggctacagt gacttcgaag acgatatccg gcagctggga gagcatcttg
    12781 gaacgtacca gatgattcag cgtgtagaaa tattgcctta ccacaccttg ggcgttcaca
    12841 aatatgaagc aatgaacaaa gaatatatgc tgaaaggagt gaaagagaat actccggagc
    12901 agatagaaaa ggctgagaaa ctattcaggc aatacttccg gaccgtacaa gtgaattgac
    12961 ttatataagt gtcgaaattc gtattcgcca cagattacac gaatttacac agataaagat
    13021 tcattggcaa tcaacagatt aagttcattc tgcggtgaat tatgacgact gcacttattt
    13081 ataattttgt aagtcacgat ataaaagtct ccctgttctt gccttaattc attacaatac
    13141 aaggcaagaa cagggagata atgtaaccgg catatttttt gccaccctac tttaataagt
    13201 gaatcgcaat cctgcctgca agttaaagtt acaaggcctt tcttttcgga tggtttgtac
    13261 tttggagcca tcatcaaaga aatacgaaac tcccggttcc acatataggc cgacatgatc
    13321 tgtcgcattg aattgcgctc ccacgacacc ggctacagaa aattgcaaag gcttcacatt
    13381 caccttatca tccgccaact ttccataaac acacttttca accattcctc cggcagatac
    13441 atagagtgta aaatatttct tttccagaaa attccagttt ccacgtacag gaatacctat
    13501 ataatgcaat ttctgactct gcatcttggt atccccctgc cgtttgatgt cagaagacaa
    13561 caacgtataa gtcaatcccg tctctacaga gaaacctttg ggaagagact tacgtacaga
    13621 cagtccgaag ctaaccggct gatgatgttc ataatccacc acggcagttg tattggactt
    13681 caggtaaggg actccttctt caaatataac ttcctgatcg gcaggaatac tcacagctcc
    13741 attcatgatc gtcatcaagt cgaccctgtt agtcatcgga cggggcgcaa aattttcgga
    13801 accatttgtc ggaagtccac ctccattacc gatacccact cccatcgacc atttaccacc
    13861 acgtttagca gaagagtctc cgataggcaa ctgatacttg tctttaccgg acggtcgccg
    13921 cgcttctttc ctctttggag gctgcgctgt cacactttct tttttctcga ttgccgcagt
    13981 tgcttcctgt tgcggctcag ctctcttttc ctccgtcact gcctccggtt gcttctctgc
    14041 cagggaggat acctccggaa caatcaccgg atcagtattc tttgccaaat agcccgaaac
    14101 agggttaata ctcgtcgttc ctaccggctt aacgggttcg gatacagcta cctgtacatc
    14161 cggcaaggca ggttccggca atacatccgg gttgacagcc agtgaaggag ccgttgcata
    14221 acggatttca tcagctaccg gactattcag aaaatacaaa ctgacagcag tcgttaccac
    14281 caataccaca gctgccgcag caaccgccca ccggcgatac ggatatattc gtttttcggt
    14341 tacaggcatc agttcccttt ccagtcgttc ccaaccggaa gcaggcatcg gctccgaata
    14401 atcttcgagc ttatccttga atgctttaat ccatttttcg tcttctttca tcattctatt
    14461 tcatttttga aatccaaggt tcacctcagt atctgtaaat acatgtcaac cattggtcac
    14521 caaccattct ttcactttct ttgccaatac actttttgcg cgaaaaagct gtgaggcaga
    14581 agatttttca ttaatcccca acatctgtgc gatttccttg tgcgacttat cttcaaaggt
    14641 gtataaattg aatacggtac gatatccggc ggggagttca ttaataaatt gcatcagcac
    14701 tttctgtggt attgcttcaa cagccgaagc atccggttct tcatacgttt cgggaacttc
    14761 atccagtgcc gtggtctggt tcatcacgtc gttctttctt aagaactgta aagccgtatt
    14821 caccattaca cgctccatcc atgctctcag agagccttca ccccgccagg taaacttgtc
    14881 gaaggagtcg aaaatcttca ggaaaccgtc gtgtaccaag tcttgtgcca tgtccctgtc
    14941 tccggcataa cgaagacaga caccaagcat gcgccctgcg tactgctcat aaagttcttt
    15001 gcgggcacga ttatctccct gcctgcaacg ttccgacagc tctaattcat tcattctcct
    15061 aaacacgtgt ttaccttata aatgcagcaa agatagaaat actgcacaga gagaacaact
    15121 cttttatcac ttttgtttct ttaacatttt aggatgcaat atttcatcat ttcctgcatt
    15181 ttctcaatac aataaagaat aaatctcaat ggataaatag gataaaacca acaagaaact
    15241 tatgaagaaa tttaatttaa taacttttgc cgtcatcctg atgttattgc ccattttaca
    15301 gtcatgtctg gacgatgcca acaacgacga gtgggtcact tgtcctccgg gtggaatatt
    15361 ggccatcggc acaatgaaga ttcccaatgc ggacactcca agggactttt tcattgcgtt
    15421 ggacaatgga gacaatgtac ttccggcaga tacggccgat atacgcaaca ggaaatacac
    15481 tgttgcagaa ggtcaaagag tcttcgttgg ctatctgcag atgggagaag agaaacccgg
    15541 atatgagaac ggtaaaatat tcacgataga agatatattg acgaaagaga tcatcccact
    15601 gacggaagct acagcagaca gcattggaga cgaccgtatc aacgtcacag cgcatgcact
    15661 tacgaaagat tatctgacca tcgaatatca atatctgggc agcatgaatg aaaataaaaa
    15721 acacatgctg aacttggtac aaaacgaaat aacaggtccc ataaaagatg acggatatat
    15781 ctatctggag ttccggcata atgcctttaa tgactccccc aatcaattgg gttcgagcct
    15841 tgtttctttc aagctggata gtatagccga gcaattggcg acagccaaag gaataaaact
    15901 ccgtgtgaac accatttatg acaatataca gtatgtcaca atagatatca acgaagacaa
    15961 aaacttaaaa ataaaatcat ttcattctca ataaaactat aatcggcaaa acgaaatgcg
    16021 agcggcataa aaaacgaaat gcgataatca gggtataaaa cgaaatgtga aaaatttata
    16081 gcacacgcac aatataaaaa ggctttcaaa cgtcatttga atggggtttg aaagccttta
    16141 aatttatagc attttcacat aaaaatcacg ttctaatatt tgcgcaattc attagaaatg
    16201 actatcttta tacagtattt aggaggcatc tgttatgttg gcatcgttgc tatctttgta
    16261 gtcaaacaaa gttcgctgcg ggtgttcttc ataattgcat accatccatt cctcttgctt
    16321 tcttcggctt gtctttgatg cgctgatggt tctttctacc cggtggatta tccatccgtt
    16381 tttgtttgcg tattcctcta tcattggcag gggaaacatt gtcagcatga acttaccttt
    16441 cacctgctcc aaaagctgca ggagtttctc catgcaatac tcatcaaacg taccctcgta
    16501 atggccgcaa tcgctattga tatagggagg atccacaaaa tgaaacgtat cgggcgagtc
    16561 gtaagtggag atgacatcca gcgcatcccg gttctctatg gtcacgttat caagccggga
    16621 gcatagccat tcggtaaact catcctttgc gttacgcagt tttttcggca ttccaccacc
    16681 aaagtcatag ccgaacgaac cgtccatcat gctggcaaag gacattttac acagcgccca
    16741 aacagcccac gcccgctgta ccggctgaaa gaattgagga tactgcagga tatgtccggc
    16801 atgggcgtgc atatcccggc tgtgcaaagt cttttcaatc tcctgtttca ggtcacgata
    16861 atagacttta gccatccaat agaagttcgt tatatccatg ctaatatcgt ttataacctc
    16921 gccatcagcc ggacgcttgg caaacaatac tgcagcaccg ccgcagaaag cct
//
