LOCUS       c00073_gnlPro..        13258 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DDJPDHHK_73.
ACCESSION   c00073_gnlPro..
VERSION     c00073_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:33:00
            Original ID  :: gnl|Prokka|DDJPDHHK_73
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 91274
            Orig. end    :: 104532
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13258
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[101274:104247]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13258
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13258
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             192..2723
                     /locus_tag="ctg73_72"
                     /transl_table=11
                     /translation="MKNIKIVTTFFICLLLLSACSDDWKENALTAKFTFDKTTYYVGEE
                     VCITNETVGGEGNYTCQWDLGNGETSTEVAPKVTYETNGAYTVTLHVKDSKGNYAMAHK
                     LLTIEAEPLPEVGNVKLKWVGAHVLGEIRSTAPAVSDDNNVYMTSNDHYLRKFSAATGE
                     QLWEFDLWTSADGDSPSGNTHTTPSIDTDGTVYVGTGDTSGKVGRVYAINPDGTKKWVV
                     AGDAEKGFWNKGQASKPRINYLTCAIGENHIYMGNGGSTGSVLAVDKNTGYRVGYVANA
                     DNSGGPSGGVSAGIALANNTLIWAGGKNGLFGASASALNTGGNVMWAWQIYSSGNDKPS
                     ENMNASVAVDATGTIYGIATFPSIGSSAFAIGSDGVEKWRTSLGNVGTLDQGGVVIGLD
                     GSIIVTVKRAPGEATGGIVALSPNGVVQWHYGVPEDVSGCAAIDQAGNIHFGTQSGNYY
                     IIKPESSEEQLILKKDLAALISESDSPLKDNWEAGIGKIWSSPTIGPDGTIYIGVTHTV
                     DPSKSVLVALEDEGITGCAASAWPMKGKDSRHTSAQLGGSGENPGGEPGGQLPITGNLK
                     TDLKNLFDDSSYKVWLCAHRANTQKGIADGIPENSLTSIEYAINAGVEMIELDARPTSD
                     GILVLMHDNTIDRTTNGSGAVGDYSYQQLQQLYLKDAAGNLTNERIPTLEDALKKGKGK
                     VYFNLDIVNKNVAVATMVALLKKLDMENEVLLYVSNNRNYAYDLKAANSTLLLHPMAKA
                     SDDITYFASSYTDNVQMMQLSTSDALAGAMTEDIKSKGWLLFSNIVGANDTNMLSDNYS
                     GLVGMINKRINVVQTDYAELAAKYLKSKKYR"
     CDS             2754..3674
                     /locus_tag="ctg73_73"
                     /transl_table=11
                     /translation="MKNYLIIGIILLFPFRLFADEPVKAIYAKITNPDNKEVTVVAHRA
                     DWRFAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLRLKNGAALRTKHRVPTLEEALLTAKGRVMVNLDKAYPIFDEIFPILEKTGTVE
                     QIIMKGSKPVAEVKKDLGKYLDRIIYMPIVHLDRPGAMQQIDDFMKELHPVAFELLFES
                     DTCQLPQQVRTKLEGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDKLGATIIQT
                     DRTAYLLEYLQVRKKRNEHKIDVFH"
     CDS             3691..5046
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 156.6; E-value: 2.8e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg73_74"
                     /sec_met_domain="MFS_1 (E-value: 3.7e-48, bitscore: 156.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFKILDFYKISSPLAGGETDSEDSSRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVVRKPIVEEGVFSETQLGIIGSCLFFVYAVGKLTNGFLADRSNVRRFMST
                     GLLCSALINLCLGFTSSFYAFALLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGIIGILGFFMMLVFMRDTPQSQGFLLNK
                     NSSSVDSHSLSGKQTEDFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQ
                     KGYSTLDASFIISISSICGIIGTVFSGIISDKMFSGSRNIPALVFGLMNVIALCLFLLV
                     PGAHFWIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEVD"
     CDS             5173..5307
                     /locus_tag="ctg73_75"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             5316..5561
                     /locus_tag="ctg73_76"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             5682..5984
                     /locus_tag="ctg73_77"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(6223..8340)
                     /locus_tag="ctg73_78"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSSTYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVNSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(8428..8658)
                     /locus_tag="ctg73_79"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             8852..9355
                     /locus_tag="ctg73_80"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             9530..9973
                     /locus_tag="ctg73_81"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_82"
                     /sec_met_domain="Radical_SAM (E-value: 3.1e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10745..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_83"
                     /sec_met_domain="Gly_radical (E-value: 3.6e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEVRIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
ORIGIN
        1 accgcgagtt gtatgcagaa ggtcaacgat ggtatgattt gaagcgaacc aaccgtttgg
       61 acttgttttc ttccttgaac ggtagaaact acctgatgta ttatcctgtt ccccagtcgg
      121 aacgcgattt ggcgggagag gaaaattacc ctcaaaatga aggctattaa ttatcttaga
      181 aagaacaaag tatgaagaat ataaaaatag taacaacgtt ttttatctgc ttgctgctac
      241 tttcagcatg ctcggatgat tggaaggaaa atgcgctgac agctaaattt acttttgaca
      301 agacaaccta ctatgtaggc gaagaagtct gtatcacgaa tgagacagta ggcggagaag
      361 gtaattatac ctgccaatgg gatttaggga atggagagac ttcaacagaa gttgctccta
      421 aagtgactta cgaaacgaat ggagcatata cagtgacttt gcatgtgaaa gacagtaaag
      481 gaaattatgc aatggctcat aaattattga cgattgaagc tgaacctctg cccgaagtcg
      541 gcaatgtgaa actgaaatgg gtaggtgccc acgtgttggg cgaaatacgt tctacggctc
      601 cggcagtcag tgatgataat aatgtatata tgacttccaa tgaccattat ttgcggaaat
      661 tttcagccgc taccggtgaa caattgtggg agttcgactt atggacatcg gctgacggtg
      721 attctccgtc cggtaatacg cataccactc cgagcattga tacggacggt actgtgtatg
      781 taggaacagg cgacacaagt ggcaaagtag ggcgcgtata tgccatcaat cccgatggaa
      841 caaagaaatg ggtcgttgcc ggagatgctg aaaaaggatt ttggaataaa ggacaggctt
      901 caaagcctcg tattaattat ctgacttgtg cgattggaga gaatcatatc tatatgggta
      961 acggcggctc tacgggatct gtgcttgctg tcgataagaa taccggttac agagtaggtt
     1021 atgtggcaaa cgcagacaat tccggaggtc cgtcgggggg agtatctgcc ggaatagcat
     1081 tggcgaacaa cacattaatt tgggctggtg gaaagaacgg cttattcggc gcgtcggcgt
     1141 ctgcactgaa tacaggtggt aatgtgatgt gggcatggca aatatatagt tcgggaaatg
     1201 ataagccttc agaaaacatg aatgcttccg tagctgtgga cgcaaccggc actatatacg
     1261 gaattgccac cttcccgagt ataggaagca gtgcgtttgc tattggaagc gacggggtcg
     1321 agaaatggcg tacttcgtta ggaaatgtag gaacactaga ccaagggggt gttgtgatag
     1381 gcttggacgg aagtatcatt gtaacggtaa aacgtgctcc gggtgaagcc acaggaggaa
     1441 tcgttgcatt atctcctaat ggagttgttc aatggcatta cggtgtgccg gaagacgtca
     1501 gtggatgtgc ggcaatcgat caggccggaa atattcattt tggaacgcaa tccggtaatt
     1561 attatatcat taaacccgaa tcctcggaag aacagctaat cttgaaaaaa gacttggctg
     1621 cactgattag cgagagcgat tctcctttaa aagataactg ggaagcgggt atcggaaaaa
     1681 tctggagttc gcctacaatc ggaccggatg gaacgatcta tattggcgtt actcacacgg
     1741 tagatccgtc gaagagtgtc ctggtagctt tggaagatga aggtataacc ggatgtgcag
     1801 cttcggcatg gccgatgaaa gggaaagaca gccgccacac cagtgcacag ttgggaggct
     1861 cgggagagaa tccgggaggc gaaccgggcg gacaattgcc tattacagga aatctgaaga
     1921 ccgatttaaa gaatttattt gatgatagtt cctataaggt ctggctttgt gcccatcggg
     1981 cgaacacgca gaaaggtata gccgatggca taccggagaa ttcattaact tccatagagt
     2041 atgcaatcaa tgcaggagta gaaatgatcg aacttgatgc acgtcccacc tctgacggaa
     2101 tattggtgct gatgcacgat aatacgatcg acagaaccac taacggaagc ggtgcggtag
     2161 gagattattc ttatcagcaa ttacagcaac tctatcttaa agatgcagca gggaatctga
     2221 caaacgaacg aatccccact ttagaggacg cattgaagaa aggcaaagga aaggtttatt
     2281 ttaacttgga tatagtcaac aaaaacgttg ccgtagcgac aatggtggca ttacttaaaa
     2341 aactcgacat ggaaaacgaa gtcctgcttt atgtttcaaa caaccgtaat tatgcatacg
     2401 atttgaaagc ggcgaacagc actctgttac tgcatccgat ggcaaaagct tcagatgata
     2461 ttacctattt tgcttcatct tacacggaca atgtgcagat gatgcaactt tccacctcgg
     2521 atgctcttgc gggagcgatg acggaagaca ttaaatccaa aggttggctt ttattctcca
     2581 atatcgtagg agcgaatgat acgaacatgt tgtcggacaa ctattcgggg ttggtaggca
     2641 tgataaacaa acgtattaat gtcgtacaga ctgattatgc cgaattagct gccaagtatt
     2701 taaaatccaa aaagtataga taatccccca aagtatagat gataaaaatg aatatgaaaa
     2761 actatctgat aataggaatt attttgctgt ttcctttccg cttgtttgca gatgaaccgg
     2821 tgaaggcaat ttacgcaaag attacgaatc ctgataataa agaagtaacc gtagtcgccc
     2881 atcgggcgga ttggcgcttt gcacctgaaa attcgctggc agcaatagag agttctatcc
     2941 ggttgggagc cgatgtcgtg gagttggacg ttcagaaaac caaagacgga cagttgatcc
     3001 ttatgcatga taagactttg gatagaacga ccaccggaaa aggtaaggtt gccgagtgga
     3061 cactggattc tatccgtaca ctccgtctga agaatggcgc tgctttgaga accaaacatc
     3121 gtgtgcctac attagaggaa gcattattga cggctaaagg gcgcgttatg gtaaatttgg
     3181 ataaggctta tccgatattc gatgagattt tccccattct ggagaaaacc ggaaccgttg
     3241 aacagatcat catgaagggg tcaaagcctg ttgcagaagt gaaaaaggat ttgggaaaat
     3301 atttagaccg gatcatatat atgccaatcg tacatttgga tcgaccggga gctatgcagc
     3361 aaatagatga tttcatgaaa gaacttcatc cggtagcctt cgaattgttg ttcgaatcgg
     3421 atacttgtca actcccccaa caagtgagga cgaagctgga aggaaaaagt aaaatctggt
     3481 ataataccct ttgggatacg atggcaggcg gacatgatga cgacaaatca ttggaaaacc
     3541 cggatgaagg atatggatat ttgatagata aacttggagc aacgattatc cagactgatc
     3601 gtaccgctta tttactggaa tacttgcaag tccgtaagaa acgtaatgag cataagatag
     3661 acgtctttca ttaatatgta aacttcggtt atgtcattta aaatattgga tttttataaa
     3721 atctcttccc cgctagccgg gggagagact gattcagaag attcttcccg ctttaagcgc
     3781 atccgttggg ctacattttt gtcggctact accggatatg gcatttacta tgtttgtcgt
     3841 cttagcatga atgtagtgcg caagccaatt gtagaggagg gagtattttc cgaaacgcaa
     3901 ttaggaatca tcggttcctg tctgtttttt gtgtatgcag tgggtaagtt gacgaatggt
     3961 tttcttgctg accgtagtaa tgttcggcgt tttatgtcta ccgggttatt gtgttccgct
     4021 ttgataaatt tatgtttagg tttcactagc tccttttatg cttttgcttt actttgggga
     4081 ttgaacggtt ggtttcagtc gatgggagca gcatccggag tggtttcgct cactcggtgg
     4141 tacagtagta aagaacgggg aactttttac ggcttttggt ctgctagtca taatttgggt
     4201 gaagcattaa cctttatttc catagcctta ttagtcagtt ggatgggatg gaggtacggg
     4261 atgattggag ctggcattat tgggatatta ggtttcttta tgatgcttgt ctttatgcgt
     4321 gatacgccac agagtcaggg attcttgttg aacaaaaatt cttcatctgt ggattcccat
     4381 tctttgtctg gtaaacaaac ggaagatttc aacaaagcac aaaaggctgt cttgaagaat
     4441 cctgcaattt ggattttggc tttatccagt gcatttatgt atattagccg ctatgcggta
     4501 aatagttggg gtgttttcta tctggaagct caaaagggat attctacgct ggatgccagt
     4561 tttataatat caatcagttc tatctgtgga atcattggca cggtattttc tggtatcatt
     4621 tccgataaaa tgttttccgg cagtcgtaat attccagctt tagtatttgg gttgatgaat
     4681 gtaatagcac tttgtttgtt tctcttagtt ccgggagctc atttttggat agacgtgttg
     4741 gcaatggttc ttttcggttt aggtatcgga gttttgatct gttttctggg tggtttgatg
     4801 gcagtggata ttgctccccg taatgcttcg ggtgctgcat tgggagtagt cggtattgcc
     4861 agttatatcg gtgccggatt gcaggacgtg atgagcggta tactgataga agggcaaaag
     4921 actgttcaga atggagtaga tgtttatgac ttcacctata tcaattggtt ttggattggt
     4981 gctgctttgc tttcggtgtt gtttgctttg ctggtatgga atgcaaaatc aaaagaagtg
     5041 gattaaagtg agtacattag gttagaatat aagtctttgt tttcgaggta ttagacacca
     5101 ttccgggaag taagtaatga ttgcttatct ttctggaatg gcttttttat aatcaattaa
     5161 atagaaagtt ttatggaaaa ttcattgaat gatgaattat tgtgttcatt gaaagatgaa
     5221 cttcgtgaag taaccgcaca aatcaatgtg catagtgaaa aattaatgga tctgctcgac
     5281 caaaaaaaag aatcgtcagt caattgactc gagagatgtc gcatctcacg cctgtcatca
     5341 tcgagtatcg gggaaatccg aagcaatatg tctctgttgt gctcgatgcc atcaatctgg
     5401 gtaggttgac gtatgacgga gtagcaaatt gcgaacagac ttttcgtgcg ttagcaagcg
     5461 ttgtagatgt gataagccct aagaatggga aaacgcttag tgtagagacg ctagtgtctt
     5521 atgagaagaa aaagcgtgca ggagaatttg aggaaaaata atataaaata aaaagacgat
     5581 tgttgtatag ttgaacaaca attcgtatat ttgcagtatg gaaaagaaac gtaagatccg
     5641 tactgaaata gataaagcat taaaaataaa ggaggaatat tatgcagata aacaatcatc
     5701 aaatagtaga ttatgacgct gttcttgatg cgaaatttgg agcagaaggt actcccgaac
     5761 gtgcggaagc agaagaaaaa gcgtatgctt tctacaccgg gcaaattatc gaagacgcaa
     5821 ggaaaaaggc taagattact caagcagagt tagcccggcg tatcggttcc gaccgttctt
     5881 atatttcaag agtggaaagt ggtcagacag aacctaaggt ttctactttc tatcgcatca
     5941 tgaatgcgtt aggttgtagg atcgaatttt cgatgtcttt ataagaagcg attaaaaaaa
     6001 acatggtggg aaatttgaaa aagataactg tctttttcaa atttcccacc gtttttttga
     6061 ggaagaaaaa ggaaaaggtg agggtaggtg agggtaaatt tctaacattc gtattttttt
     6121 ttagaagaaa atagaagaat agaaataaga aatataaaaa tgaaaagttg caaaagtacc
     6181 ctcaccaacc ctcacctttt tgcgtgcgaa ggagacgaaa tcttattcat atagcctgtt
     6241 tgatttcacc tgttccgtat caataatgaa tacagtgtat cttctcccgt tttttccctt
     6301 atgaaattcg aagccgtgtt tggacatcac ttttcctagt tgggctttgg ttccgtgaga
     6361 gtattgatac cccgttcgtt cgcgaatcaa ttccgcaatt tcagtgaccg tcagataatg
     6421 caccttttcg aaacgttccg gtttgcggat atgtgtcaac accagttctt cttccggtga
     6481 gtggaaaatg aaatcctcgt tgttctcttc aatccgtgag ttttccgact gggtgaacca
     6541 atactgatac cccggcttgt tgagcagata cttgatttgt gcatacaact gcgcgtagtt
     6601 tattttgata aactccatcg agttgacatg aaagcagaga aaacggcggt taccagtggt
     6661 gtcgtgaagc acttcctgat aattgcatgt gccggcaaaa gaagccgtgt gaggaaagtt
     6721 ctgtgaacgc cgcgcgtatg gcaggcggat gctgattact ttgcgggtaa ccaaatcctt
     6781 gaagatattc agttcccgtc cgttcatccc ttcaaactca tccagattga taagcatcgc
     6841 ctgcgctatt ttggccagat catccttgtt gttcgggttg ataagaccgg tagaaagata
     6901 ggcgcgcaat tcgggcggca gcaggttgtt gataaacgta gtctttccga tgttctgtat
     6961 ttcgctgcaa agcaacaaaa cagtgtggtt caccacatcg tcttgtgtgg cggcagcgca
     7021 cattcccacc agataacgtt ccagacattc tacccaaaat ttctggtgac tagtatgcac
     7081 gctgttggca aggataccga tataatccgt tccgtcccat tcaggcagcg agtctaaata
     7141 ttcgcgaata ggatggtaag tgctgctgaa gtcggagtag atcagatttt gaattgtttt
     7201 gacggtgcac gaatagccta gttcgttcat ctccatccaa atgctgtttt ccatcatttc
     7261 gtcgagaata tggaaaggtt ccggttgctc cgtgtccgtt ttccttctgc gatattccat
     7321 gatatgaagc acttcgttgt agcgtgtatc gtaattttct ttgatatgtt gctcaatctg
     7381 taatattcgc ttctgcgtac tattcagctt gcgggtgtcg aattcctcat tgtgtccgta
     7441 agcactcccg atcagtgcgt ccatttcatc cgcgggaaga tcggtgaact ggctcttgat
     7501 aaaagctgcc gcctcttcct gggggacgcc gtagcgattg tacatacaag ccaggcaatg
     7561 caggtagttg ttccggttgc cggtgacgta cttttcggat ttattgtgat aatagttcag
     7621 agtcaccatt aaggaagcgt gcgaggaatg gtagttgagt gccacttgtt cggtgagggg
     7681 attgttgtct ggtgctgtcg tctttttctt tttgccggat gcccttttct tcttttgaga
     7741 cttgaagaac atcggtggct gttccacgat gacagctgtg gcatcgggat tgaaataaat
     7801 atccggatcg taagagaaca ggcaagtgcg gctgacatct tgtccggaag tgtcgacctc
     7861 aactccgcag agctgggcat aaaaggaagc gattttgtga taagcggcat gatggaaatc
     7921 ttcaatttcc tgaatcgttt cgggcaatgt cccgtccgtc cggcatacac gtaccacgat
     7981 tttcagtccc attcctttgg gactgatgaa agcgatgcgg gtgtgggcac acttttttgc
     8041 cagtgcgagg atgcgtgcca atgcttcctg tgtctgatgg tcgatgtcta ccacgatgta
     8101 tcccagatac ttgacgagag ttgcgtttga acgtcctccc cggtagttgg ctgaaaaggt
     8161 gatttccggt agttctattt tcttttcgtt ggctgctttc tcgccttgtt ccgcgaagat
     8221 tcggcgcacg tcctccactg tttcccggta tgtgccgttg ctgatggccg atacgatttc
     8281 ttcttctgtc atttcggcta tgacgcggta aaagtcttga aagatggtaa aatgctccat
     8341 gttggtttgt tctttttaat ttgcggttgc aaagaaattt gtttgtaaaa taatagaatg
     8401 gaacttttcg tttttttgat taagttccta gggttctccc aaatagcgta tgatcgttgc
     8461 cacttgccgg ggagagagaa ggcggttgcg ggcacgatag ccttcttgtt cgagttcttg
     8521 caggagcgga aggttgtaga caatccaacg acgtagtatt tgtaaggcta ctttgagaca
     8581 tacgttgggg ttgtaaagat gagctagttc cgacttttta taagtgcgga tatgaaacgg
     8641 ctgatccgga taatacatga tgaatgatat ttggtttatg ctataaagtt actgaaaatt
     8701 aatggtttat taaaagaata acgtcattat tattcataga atatcaggaa acttcgttgg
     8761 ggaatccgga gggtgaaaaa tgtgttatct ttatgtcgtt aacaaataag gaacgcgttc
     8821 gaaatgtatg aaaatttaaa attattttat tatggcaatg acagtaactt attcagtagt
     8881 gccgcgcaag aatcctgcca aaaaggatga gtcggcaaag tattacgcgc aggcacaggc
     8941 ttcgggagag ttggattttg aagagttgtg cgagggaatc accagtcggt ctacctgtac
     9001 ggagacagat gtgcgtgccg ccatttcggg tattctttat gaggcgaagc gtgcgttgaa
     9061 agcgggaaga atagtccggc tgggtgattt gggcagtttg cagatcgggt tgaacagtga
     9121 aggagctgtg tcggtcaagg agttttcaag ttcgctgatt acggctgccc atattatttt
     9181 tcgtcccgga aagacgttgg cggacatcac gaagattctt agctaccagc aggtaacgac
     9241 gcgtgcggtg gcccaaacgg gcggtagcgg caatgaagga gaagatgatg acaaaggttc
     9301 cggtggcggt tcagacggtg gtggaagcgg agaagctccg gatccggcag catgataact
     9361 ttaatattgg atcaaatgaa agaaattgta actaagattt tggatgtaat catgttcctt
     9421 gtgcctttct tcggaaaaag aaagcggaac agaattgtga gagaggtgcg cttcaatgct
     9481 acccataagg aagtgtgtaa tgtgaaaacg acggaaaggg agaaggacga tgagaaagat
     9541 tagtctgatt gtgattcact gctctgctac ccgtgtcgat cgcgacttca cggcgaagga
     9601 tgtggacact gcccatcgct ttcggggctt ttcgtgttgg gggtatcatt attatatccg
     9661 caagtcggga cagatagaac cgatgaggga tgaagatacg gtgggtgctc atgcacgcgg
     9721 ttttaatgcg attagtttag gggtgtgcta tgaaggcggg ctggatgaga acggaaaggc
     9781 agcggataca cgtacttccc gccagaaaga ggcgatgcat cgtctggtaa gcgagttgtt
     9841 gcagcgttat ccggatgcaa aggtggtcgg tcaccgggac ttgagccctg acaccaacta
     9901 caacggaatt gtagacccct gggaacggat caaagaatgt ccctgttttg aggtgaaagc
     9961 agagacatgg tgatttttat cctatttatt actgtggtgg ttaattgacc accacagtag
    10021 tgaaatactc tttaaatacc tccgcggctt tttcaagttg ttcgggggta ttttctttta
    10081 cgtctttcag cttgtattcc tgctccatcg cttcatactt atgtacgcct aatgtatgat
    10141 aaggcaggat ttctactcgt tgcaccatct tatattttcc cagagcctct cccaagcggc
    10201 ggatatcctc ttcgaaatcg ctgtatccgg gcactaatac ataacgcagc cagaaaggtt
    10261 tctcgttttc ttccagccat gctgccgtgc ggatggtttg ctcgttactt cttccggtca
    10321 gtgcttgatg gcgtgccgga ttgaactctt taatatccag caatacaaga tccgtcagtt
    10381 tgaaaagttc ttctacttct tcgttccaga taccgccgtt gctgtctatg catacatgta
    10441 ttcccttttc tttcagttca cgcactaaag ggactagtgc tttggcctga aacgtaggtt
    10501 ctcctccgga gaaagtgact cctccgcgtt tcccgaaaaa aggacgttgg ctcatagcca
    10561 tgcggacgat ttcttccggt ggggtaggtg tgcctccttt tccggctatc gtgtcggggt
    10621 tggcacaata caggcagcgg aaattgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcgtcata ttgagtagat
    10741 ctgattacat acgttcgtgg aagctacggc tgataacttc caattgatgt tcgcggctca
    10801 acttcacgaa gtttacggca taaccggaaa cacggatggt gagttgcgga tatttttccg
    10861 gatgttccat ggcatcgtaa agcatttcac ggttcagtac gttcacgttc aggtggtgag
    10921 cgcctttggt gaaatagcca tccatcattg tcaccagatt ttctacgcga tcctcttcag
    10981 tagctcccag tgatttgggg acgatggaga aagtgttgct gataccgtcc tgtgagtcgc
    11041 ggtaacgtaa tttcgctacg gaactcaaag aggcgatggc accgttcttg tcacgtccgt
    11101 gcatagggtt ggctcccgga gcaaaagcga cacctttggc gcgtccgtcg ggagtagcac
    11161 ctgtcttctt gccatacatc acgttggaag tgatggtgag caaagataaa gtaggacggg
    11221 catttttgta aaccggaagt ttcttcaatt cttcgctgaa gaaatagacc aggtcaacac
    11281 ccaggtggtc taccttgtcg ttgtcattac cgaagcaagg gaattcgcct tgaatatcga
    11341 aaccttctgt cagaccgatg tcgttgcggc gtgcggtcac tttggcatat ttgatggccg
    11401 acagtgaatc gagggcgata gaaagtccgg ctacaccata agcaaggttg atgcgtgggt
    11461 tggtatctac aagagccatt tgggcttttt cgtagtaata cttatcatgc atataatgga
    11521 tgatgttcat cgcttcgttg taaacacggg cgatttctgt caataccttc ttgtagttgc
    11581 tcattacttc ttcgaagttc agtgtgtcgc tggttagtac ggggatattt ttcaccatta
    11641 ccgtaccggt gttttcgcaa cgtccgccgt tgatggcaag caacagggct tttgccaggt
    11701 tgcaacgtgc gccgaagaat tggatttgtt ttccgatttc ctgataagat acgcagcatg
    11761 cgattccgta atcgtcagac tggcgcactt cacgcatcag gtcgtcgttt tcatattgga
    11821 tggaagaagt gtcgatagat acttttgcgc agaattcttt gaatccttcc ggcagttccg
    11881 ggctccacaa tacagtcagg ttcggttccg gtgaagggcc gaggttgtag agtgtttgca
    11941 gaaagcggaa agaagtcttt gtcaccttgg tacgtccgtc gttgaggcgt ccacccaggg
    12001 attcggttac ccatgtcggg tcgccggcga agatgtcgtt gtaagattgc atacgcaggt
    12061 gacgcaccat acgcagtttg atgacaaact ggtcgatcag ctcctgtgcg aaagattctg
    12121 tgatggttcc tttgctcaat tcatattcca tataaatgtc gaggaacgaa gagacgttac
    12181 ctagtgacat agcagcaccg tcttgttctt ttacggcagc aaggtaagcc atgtataccc
    12241 attgtactgc ttcttgtgcg gtgtaggcag gacggctcaa gtcgagtccg tagtattcgc
    12301 ccattacttt catgtctttc aatgccttga tttgctctgc cacttcttcg cgcaggcgga
    12361 tgcggacttc ggtcatcgga ccggtaaggt tacgcaagtc ttcttttttt gcctcaatca
    12421 gtcggtcgat accatagaga gccatacggc ggtagtcgcc gatgatacgt ccacgggcat
    12481 agttgtcagg aagtccggtg aggaatccca gagaacggaa cgaacggatt tcttcggtat
    12541 atacgtcaaa tactccgtca ttgtgcgtct tgcggtagtg agtgaatata tcttttacac
    12601 ggtcgtccac ttccacgccg ttttcgtggc aggctttgct cactacgttg atacctccga
    12661 aaggcttgat ggcacgtttc agaagttcgt ctgtctgcag accgacgatc agttcatttt
    12721 ctttgtcgat atatccggct ttatgagaag tgatggttga gacggtgaca ttatccagtg
    12781 agcgtacgcc gttattggct ctttcttctg ccagtgcttc gaggcagcgg ttccatacag
    12841 cttttgtgcg ttcggtaggt ccttcgagga aagaagcatc tccataatac ggagtgatgt
    12901 tgtgactaac gaaatctctt acgttgattt ctgtgctcca aagaccgtct ttaaagatct
    12961 tatttaattc cataaatgat aaaattagag gttgtagtta tccttttctt tagagcgcac
    13021 aaagttacaa cgttttttca tataatcagc ataaatatgc tctattttat gcttttcaac
    13081 ataaaatacc tagatattgc tattctttgg aaatgatgtt cgtgattttt ttttgtgaaa
    13141 actcttgtaa gtttaaaata tattcgtacc tttgcaccgc ttttaacgaa aagcacttct
    13201 gataaagaag ttttggagag gtggcagagt ggtcgattgc ggcggtcttg aaaaccgt
//
