LOCUS       gnlProkkaKMECMAFH_53   10485 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KMECMAFH_53.
ACCESSION   gnlProkkaKMECMAFH_53
VERSION     gnlProkkaKMECMAFH_53
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:07:22
            Original ID  :: gnl|Prokka|KMECMAFH_53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10485
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10485
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5706:7341]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5707..7341
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10485
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10485
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             331..1389
                     /locus_tag="ctg53_1"
                     /transl_table=11
                     /translation="MRMEYVFPQLFSPDDVDIRLQYISVSQLEKMVETGKLCIPGTEEL
                     QRMSNAWNDKERSSFIESIMANLPIQLIYLDGSKTPWTVIDGVQRISSLHKFLQNEFVL
                     DGLEYFSKECEGMSFSSIPFYLRSRIESTNIVAYVINPGTPDAVKFNIFKRINKIGKQR
                     NREELRNAFFQGSVSKCIAELAESHEFLQATHKMMSQKGMSDRELVCRYFAFRLLRPFF
                     DTTETMDDFLDKGMDALSALPENDFERETARFKTVMQRCYDVLGDITFINIKATRKRIN
                     KNLFDAFSYSISRLNDNEYQSLLRQSDRFEEEYKRLFEEKGFLCGKELRKTSTEAVRKR
                     FDTMDRFIRKFT"
     CDS             1396..2520
                     /locus_tag="ctg53_2"
                     /transl_table=11
                     /translation="MIKEIRLKNFKVFEEESFNIKPLTLITGVNGMGKSTLIQSLLFLK
                     QNYELGYLSNPKKKLRLKHDFVNLESAGDICYTFAEEKSVCISIKEDNGNEYQWVLDTS
                     EAGSEEVGYTYTGSDIHGLSLFDDRFIFLEAERWGPKAQYNKSEARAYNTSLGIQGELT
                     PAYLNNALSVNEEIGIKEMRHPNLKEEQIQLTENVNAWMAQIMQVPSLKANTTEIDKDK
                     IRLEYGMAGTKGKKYSALQVGFGFTYCLPVIVALLRAKADDLLVFENPEAHLHPAAQVE
                     LGKLMALAAGKGVQIIIESHSDHILNSLRLARKEKVISQEDLNVIFVQRDFGAGDDMEV
                     TYIDEIQITDEGKLNKRPKNFFDSWDDVLTRLID"
     CDS             2525..3436
                     /locus_tag="ctg53_3"
                     /transl_table=11
                     /translation="MEAYLNELSVKAFSNNKDAQDAFSLLGRCLSKMSELGVSNVRMTN
                     EAMGKGMLPGQTWNRILNNETVIDKDLKSVLIAKLCTLEPVDSLEDKHNVLGFSYNGIP
                     CKGLGWASEAMENTLALGFRQKDAWDNGNYDVDISLLDEDGNELPFTSGCKHVVSPDGV
                     ETHRDFLLKNINMPTNGKVLSKRTAKLFPHLRFAEQASDQLDKIKDPAVVQQIYWRLSD
                     LERVAANSTSPVSPEKFRYKTTPESETRSRLSQLKILFSDGETRLCSWHSRFTPGAGRI
                     HFCPNESEQIFYIGYIGEKIAD"
     CDS             complement(3533..5710)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 283.3; E-value:
                     6.5e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg53_4"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.6e-37, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVSVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGYYYELINNQLIAMG"
     CDS             complement(5707..7341)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_5"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     3.8e-22, bitscore: 68.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKTNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCE
                     YMASYGTSEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEE
                     EAIPKKLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTR
                     IFRKVEPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVF
                     HITTNATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIR
                     EVSEEYLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKT
                     DKQLAQFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKAR
                     YFNSCYIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPS
                     CRSCWAGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQM
                     ERMYFQANDITLGAFHTYVKEQQDVAP"
     CDS             complement(7382..7576)
                     /locus_tag="ctg53_6"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             complement(7998..8663)
                     /locus_tag="ctg53_7"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYTPGKKEKEE
                     EGTLCGTGSGDVMGATRFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGIAPVITSDDLLNAGDVLLNLDGAQMNEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELMDQYIGNDGNVLPVKRKKNEGQPEHAWRQFL"
     CDS             complement(8651..9103)
                     /locus_tag="ctg53_8"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMASPAEAPETKSRPAT
                     SQEKQEKNSAGSPKQQIRKSTDEASGPDEYRQRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPDMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             complement(9112..9873)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 75.5; E-value: 8.1e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg53_9"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKAYSILNSTPEEARETAGRFLEKS
                     GLDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGIKGFFF
                     RSTLFPPPPSALRGSNLDLLATEIETILKLQ"
ORIGIN
        1 cattgtcgaa tcgtttgggt aagacataaa tttgaattcg acggcgaaga taaatggtgt
       61 taacaggcta tggttcagag gtttcatcag atgtcactac atgtcatcag atgtcatagc
      121 aataacatat ttgcctaatt catactacat tttgtatgat acaagattta tctgcgtgat
      181 tgctcacttt tctttgaaaa ttaagaagac taatgttttt acctttgcaa ataaaatcag
      241 aatattacca agacaaggtg gcaatcatga ttttttgttg tatttttgcc cagacaggta
      301 tatataggct aattgataat taggattata atgagaatgg agtatgtttt cccgcaattg
      361 ttcagccctg atgacgtaga catcaggttg caatacatat ccgtcagtca actggaaaag
      421 atggttgaaa cgggtaaact atgtatacct ggaacggagg aactgcaaag aatgtcaaat
      481 gcctggaatg acaaagaaag aagttcgttt atagaatcca ttatggcaaa tttacccatc
      541 cagttaatat acctggatgg aagcaaaacc ccatggacag taatcgacgg ggtacagcgg
      601 atcagttcac tccataagtt cctccaaaat gaattcgtgt tggacggatt ggaatatttc
      661 agcaaagaat gcgagggaat gtctttttcc tccatcccct tttacttacg aagccggatt
      721 gaatctacaa acatagtagc ttatgttatc aaccccggca ctcctgatgc tgtaaagttc
      781 aatattttca agagaataaa caagataggg aaacaacgca acagggagga gctaagaaat
      841 gctttctttc aaggttccgt gtcaaagtgc attgccgaat tggcggaatc tcacgaattt
      901 ctgcaagcca cccataaaat gatgagccaa aaagggatgt ccgaccggga acttgtatgc
      961 agatatttcg ccttcagact tcttcggcca ttctttgata ccacagaaac catggacgat
     1021 ttcctggata aagggatgga tgctctttcc gcattgcctg aaaatgattt tgagagggag
     1081 acagcccggt ttaaaactgt tatgcaacgc tgctacgatg tactggggga cattacattc
     1141 atcaatatca aagccacacg gaaacggata aacaagaatt tatttgacgc cttttcttat
     1201 tcaatatccc ggttgaatga taatgaatat cagagtttgc ttcggcagtc ggaccggttt
     1261 gaagaggaat acaaacggct ttttgaggaa aaaggatttt tatgcgggaa ggaactgcgg
     1321 aagacttcaa cagaggccgt ccgcaaacgg tttgatacaa tggatagatt tatcaggaaa
     1381 tttacttagt ttagtatgat aaaggaaata agacttaaga actttaaggt ttttgaagag
     1441 gaatctttca acataaaacc tctgactttg ataacaggtg tcaatggcat ggggaaatct
     1501 acccttatac agtcattgct gttcctcaaa cagaactatg aattggggta tttatccaac
     1561 ccgaagaaaa aattacgttt gaagcatgac tttgtcaacc tggaatctgc cggagatata
     1621 tgttacacat tcgctgaaga aaaaagtgta tgcatatcca tcaaagaaga caacgggaac
     1681 gaatatcaat gggtactgga caccagtgaa gccggaagcg aggaagtcgg ctatacatat
     1741 accggcagcg atattcacgg gctttcttta tttgatgaca gattcatatt tctggaagcg
     1801 gagcggtggg gacccaaagc tcaatataac aaatcggagg ccagggcata caatacctca
     1861 ttaggcatac agggggaact tacgccggct tacctgaaca acgccttgtc ggttaatgag
     1921 gagatcggca taaaagaaat gcgacatccc aacctgaaag aagagcagat acaactgacg
     1981 gaaaatgtga atgcatggat ggcccaaatc atgcaagttc cttcgttgaa agcaaatacg
     2041 actgaaatag acaaagataa aatcaggctt gaatatggca tggcgggaac caaaggcaag
     2101 aagtactcgg ctttacaagt cggttttggc ttcacctatt gcttgcctgt cattgtagcc
     2161 ctgctcaggg caaaggcaga cgacctgctt gtttttgaga atccggaagc acacctgcat
     2221 ccggccgcac aagtggaact gggcaaactg atggcactgg ctgccggcaa gggagtgcag
     2281 atcataatag aatcacacag tgaccatata ttgaacagtt taaggctggc aaggaaagaa
     2341 aaagtcattt cacaggagga tttgaatgta atctttgtcc aaagagactt tggagcaggc
     2401 gatgatatgg aggttaccta tattgatgaa attcaaatca cggatgaggg gaaattgaac
     2461 aagcgtccta aaaatttctt tgacagttgg gatgatgtac tgacccggct aattgactga
     2521 aaacatggaa gcatatctta atgaattgag tgtaaaagca ttctcaaaca acaaggacgc
     2581 ccaagacgct ttctcgttat tgggcaggtg cttgtctaaa atgtcggaat taggcgtttc
     2641 aaacgtgcgt atgacaaatg aagcaatggg aaaaggaatg cttcccggac agacatggaa
     2701 caggattctg aataatgaaa ctgtgattga caaggattta aaatccgtat tgattgccaa
     2761 attgtgcact ttagaacctg tcgacagcct tgaagacaag cacaacgtat tgggtttctc
     2821 ttataatggg ataccatgca aaggtttggg atgggcctcg gaagcaatgg aaaatacgct
     2881 tgctttagga ttcaggcaaa aagacgcttg ggacaatgga aattacgacg tggatataag
     2941 cctgctggat gaggatggaa atgaattgcc gtttacatcc ggatgcaagc atgtggtttc
     3001 tccggatgga gtcgaaacgc atagggattt tctcctaaaa aatattaata tgccaaccaa
     3061 cgggaaggta ttgtcaaaac gaaccgccaa attgtttccg catcttagat ttgcagaaca
     3121 ggcatcggat cagctcgata aaatcaaaga tccggctgtt gtacaacaaa tctattggag
     3181 attatcggat ttggaaagag tggcggctaa ctccacctca cctgtctcgc cggaaaagtt
     3241 cagatacaaa acgacaccgg aatcagagac acgcagcaga ttgtcacaat tgaaaatctt
     3301 attttcggat ggagagacca ggctctgctc ctggcattca cgctttacac ccggtgcggg
     3361 acgaatacat ttttgtccaa atgaatctga acagatcttt tatataggat atatcggtga
     3421 gaaaatcgca gactaaaact gccggaagct tgttcaggtt ggaaagcgac ggactataat
     3481 cggtatattg tgtctgttaa tcgtattccg cccgttgaaa aaaaatgcaa tttcacccca
     3541 tagcaatcaa ctggttatta atcagctcat aataataccc atggcgggcg cacaattcgt
     3601 catgggtacc ctcttcgaca atcctgcctt tatgcagaac gactatcttg tcggcatgac
     3661 ggatggtgct taaccggtgg gccactatca ggaccgtcct tcctttgcag aaatccagca
     3721 gattcccggt aatgattctt tcattgttgg catccagcga gttggtagcc tcatcaagaa
     3781 acacgaacga agggtcctta tagagcgcac gggcgataaa gatacgctgt tcctgtcccc
     3841 ggctcagccc cacgccttca gcccccacca tcgtctggta tttcaagggc agtttctcta
     3901 tgaactcttc caggttggcc tgacgggcgg cggtccggag acgtgtacgg tctatatgct
     3961 tgtcctccac tgctatattc cttgccagag attcggaaaa cacatggctg tcttgcagca
     4021 ctacgccgca gctgtgcctc cacgatgtca tatcataatc ctgcaaggga gtgtctccca
     4081 ggaaaatatt tccgcttgta ggagcaaaat agcccagcaa cagtttgaca agggtggtct
     4141 ttccacttcc gcttgcgccc acgatggcgg tggtacgttg tgccggaatg gtcagcgtta
     4201 tgtcatccag caccttggct ttgccatgca ggttatattt aaaatccagg tgttcaatcc
     4261 ggatatcctt tcgggaaatc tccggctgtt ccggtatctc tttccccgtt ctttcctccg
     4321 ccttcccatg aatcgcgctg atacgctcga tgcttagccg cacattctgg aaattataga
     4381 gaaactgcat cagctgttca atcgggatgt tcaactgccc gataatgaat tgcacggcaa
     4441 gcagcatacc caaagtcatc tccccttcaa tgacagaaac ggcggcaatg accgtcacaa
     4501 ccaggttctt ggactggctg ataaatatcc cgcccgtctg ctggaactgt tgcaggctca
     4561 aagacctcat ctggatgtca agaagctcct tttgcaacgc ctcccattcc ccggcgcgcc
     4621 ttccctcgcc gccttgcaac tttatctcct gcatgaaagt aaggagttgg tataccttgt
     4681 tgttgctggc cgactgtttc tcgaaaatca tatagtcaaa caacttgcgt ttatgcagga
     4741 aacacatggt ccacaggccg tagccgatac ttcccgccag aaagacaagg aacaggaagc
     4801 tgttatatga aaacaggacg cccatgaata tgcacaagac cattaccgag aacaagacgg
     4861 agagaacctg tccggtaaga aaatcctgca ccctgcggtg atcgacgata cgctgcaaaa
     4921 gatccccggt ggtccttgtc tcgaagaatg aaatcggcag gcggaacagt ttggcgaaga
     4981 agtcggttat caatgatata ttgacatgca tccccacaaa cagcagaaga cggttgcgga
     5041 caaactccat ggcggcagaa ccaagcacaa gcaccagctg gccgccgaga atcagataga
     5101 caagcgggat atttttatga ccgatacctt tgtcgaccat catttgcgca agcagcggaa
     5161 gcaccagctg tacgagactg ccgacaagca gggtcaaggc gaccgatgca aatgcttttt
     5221 tataagaagc tatgtacctc cataaaaaac ggaaagggga cgggactttt ggttccatgc
     5281 ccgaagagaa gtcataaaaa gcctgtgtgg gttcaagcaa caaggcgatt ccctgttccc
     5341 cgtctcccgc ccaacgcttc aggaaatcct ctttccggta tatgaccgtc cctttggccg
     5401 gatcggcaac atgatactta tccttatgaa tcctgtacag gacgacaaag tgattacgct
     5461 cccaatgaag gatacaggga caccatccgg cctgcaattc ggacagaccg accgatacgg
     5521 cgaatgtccg gaatcccagg tcctccgccg tctcgcgaat ggcctgcaag gaaaccccgt
     5581 caatcatgca gccgcattgc tcggaaagaa agtcaagggc atattccttt ccgtaatgct
     5641 tgcagaccat acggagacac gccgcaccgc actgcatgga gtcatgctgg taggacaccc
     5701 tgaacctcat ggggcgacgt cttgttgttc cttgacgtag gtatggaaag cgccgagcgt
     5761 tatgtcattc gcctggaaat acatacgttc catctgttcc agaatttccg gataatactc
     5821 cttgatatac agcaagtcct ctatctgttt ctcctgtgcg tgccgcaagc tcctgcaaat
     5881 ggaacggtca ggttcctgaa ccgcaccgtt cttgataagc gcggcggtgc agagggtaca
     5941 gaagcggccg gcccagcagg aacggcagga cgggctgtct gtcttctcaa aaaaatcacg
     6001 gtacatttgc cggacggcgg tacggttgat gcccgagttc acctcaccga caggcatgga
     6061 gaaatccgac cgttcgcaga gatgcaggtt gccgtatgtg tcaagcaaca gattggtacg
     6121 cccgatatag catgaattga aatatctggc tttgtgtgag ggtgcgtcac cgaccttggt
     6181 cagaatggcg tacacatacc gcagccatgc gctgattagg gggtcacgaa gaatatactg
     6241 gtaccgttcc tccggagaga ggcccttttc ataaagttcc ttgatccgct cccggatatt
     6301 gaactgcgcc agttgcttgt ccgtcttctt gctttcactg taatcactga attccaggta
     6361 ggaaaactga cggaccccgc cataacaacc gttcaggcta cgcccctcaa agtatctgcc
     6421 gaccttgtca tggtcatatt cgggagccag cacggcctgt atgtgtacat ggttcagcag
     6481 gtactcttcc gaaacctcac ggatcatgtc aagggcacgc tccaccaccg ttcccgtacc
     6541 ctgcccgttt ttgaacacgc ggtacttgtc attctcctcc ggaggaccgt cgaagctgat
     6601 ggcgagggtg aaatgatacc gtataaagaa ttccaccatc tcccgtgtca gcagggtggc
     6661 attggtcgtt atgtggaata cgaccttctc cgcaggtata tggtgttcct cccaaggaag
     6721 cgagagtaca tatttcacca acggttccag cagggaaaaa cgcaaaagcg cctctccgcc
     6781 gtagaaactg acggcgggag gattccgttt caggaacagt gtcctgtgtt ccggttccac
     6841 cttgcggaaa atacgtgtgt attcatggaa ataatccgaa atggctttcc gggcatcctc
     6901 ctctttcaag tgatgggagg cgtgcatttt tccttgtccg cgttgctcgt tgattgtata
     6961 ggggcaatac ctgcaacgca gattgcaggt attggtcatc tccagtgtca gttttttggg
     7021 aatggcttcc tcctcccatt gttgccataa ctgttcctca ccacgcattc ctgaaggtgt
     7081 cctcgcttcc aggggacccg gaagcaggat gccgtttccg ttaagacggg cgatgaaagc
     7141 ggcggcaccg gaagggaagg aggccgggca aggctctcct tcagaagttc catacgacgc
     7201 catgtattca cagacaaggt tcttctcagt ctcggacagc gacaggaaca tgttcgctct
     7261 gccgtcatat aaataacagg acgccccgtc aactgtgaac aatttgacca ggggaaactt
     7321 attcgttttt tgtttttcca tagtggctaa tctgtttaca aagcatcgta caatgcagga
     7381 atcaatccca gtctcttgac caccagttga aatctacacc gaaagcggag tcatcggtat
     7441 agcaaccgca gtagcataca cactcttcag acccggcggc tttcccgcct ttcgtctttt
     7501 ccaactgttc cgaagtgacc gtcttgtctt tcaggtcttc cggacggata cctagtttgg
     7561 caatctgttt tcccatagcc tttaaaattg gagttagttc atacttgcaa catttcactc
     7621 ctttaaaata ttgcaatgcc gatatagctt accggttatt caaatcccat agccgcgata
     7681 ctgacattcg tttttcctga taaatcacgg ctctataatt catttttgca atctgtctca
     7741 aatatacaga ttccattcaa aaacacaata tttttcttaa aaaaagagag gataaacgta
     7801 atgaattatt tttcattaac atcttagctt ctatatgatt ccggaaagga atccgttacc
     7861 aaccgcataa ttaaaatata tggacattta aaaagccagg tatgacaaag gaaccgggaa
     7921 caggcaacca tgatagcggt acaaggcagg tgcttccaaa gcctcttcct ttcgtatcgg
     7981 actgactgcc gccggattca gagaaactgt ctccaggcat gttccggctg tccttcgttt
     8041 ttctttcttt tcaccggcaa tacatttccg tcattgccga tatattggtc catcagctcc
     8101 tcaatcaggc ttttattctc cacctgggat gaaatcagtt caaacatgtc cgtttcccgg
     8161 atggcatgca aggtgacggc agcccggcgt tttttctcct cgttcatttg ggcgccatcc
     8221 agattaagca gcacatcgcc ggcattgagc aggtcatcgg acgtgattac cggagcgata
     8281 ccttccgtgc cgggagcctg ttcgtccagt ctttcctgtt cctctttcaa cagtctcatc
     8341 tcttccaggg gaagcccgca ctccacctca ttctccggca ccgcctcttc ctctccgaga
     8401 taatcgttcc cggtttccaa cggctggctc atgtaggggg cggcaaacgt acccgcgttt
     8461 tcgtccagat agacaaatcg ggtagccccc atcacatcac ccgatcctgt accgcacaat
     8521 gttccctctt cctccttctc ctttttcccg ggggtataga gcagcccgca aatcttacgg
     8581 atccgttttt tctgattcca taacttgtat aacaagtagc cggcacagcc gatccttact
     8641 gacaaataaa ctatttcttc cattccaaag gattttgatt tgcttcctgg ttatatattt
     8701 cattgataac atcctgatat ctttccaggt ggtccgacag gacactgcct aaaaacatgg
     8761 gaactgacat atccggcgca atgacaggca ataatttggc aacagtcctg tacaaagcat
     8821 cgtgaatata ggtctgtctt cttgaaccgg acagtctctc tttcaaaaac cgttgccggt
     8881 attcatccgg gccggacgcc tcatccgtgg attttcttat ctgctgtttg ggagaaccgg
     8941 cggagttctt ctcctgcttc tcttgggaag tggcaggccg gctttttgtt tccggagcct
     9001 cagcgggaga agccattttg tccaatgctg ttacatcccc ggccatcata cgtttcaatg
     9061 cctcctcatc cacctggtaa tccgttcttc ttttggtagc catgattgtt cttattgaag
     9121 tttcagtatg gtttctatct ctgttgccag caagtccaga ttgctgcccc tcaatgcgga
     9181 agggggtgga gggaacaagg tgctgcgaaa gaaaaatccc tttatcccga agtctttatt
     9241 gtagcgctcc gcactgggaa tgacggtttc catcgccggc aatttcagcg agcggaaaat
     9301 ttcagtgtag ctgttataca ggtctttgga cacacgtttg tccatccggt tccagaacat
     9361 atagatgcca cgcaagggca catccttatg acggtgcatg tattcccgga tggcaaggac
     9421 aaaagccatg ctgctccgca taaccattct ttcctgtgtg acgggagtga atacatagtc
     9481 catattgatg acggaccgga agacaccggg cacattcaca gttccgggga ggtcaaaaag
     9541 gacaaggtca tagtccagtc ccgatttttc aaggaaacgg ccggcagttt cccgggcttc
     9601 ctccggagtg gagttcagga tgctgtaggc tttccttccg cttgtcccga actgttccac
     9661 cagctggttt tgcagatgca cgttcttttc aatggtcccc acttcccagt cccgcatggt
     9721 gctgatactg tgctgcggat aatcgcaatc caccacaagc acgttatatc ccttcaggta
     9781 atggaagtaa ctggcgagca agacggtgaa cgtggatttt cccacaccgc ccttctggtt
     9841 gctcaaagcg acaaataaag gttccttctt cataggcttg aatttagagt gtataatttg
     9901 gtttcatatc tgtccggata tgttttttct gtttcattac gtgacaatgc atccgtcggt
     9961 atatggcaat gacgcactac ctgcccgctt gcatgaatac attgcgtacc ctattgcacc
    10021 aacgtcttgc cggttaccgg agggtattgc catggaaggt gcattgcatt catgcaatgt
    10081 aacccgccat gcaggaatgc catgcaacat gtagggcatt gcacctacag ggatgatatt
    10141 gcatccttgt catgtaccgc ctgtggcagg caagcaatac accttgcagg acaatgttcc
    10201 aatgtatgcc ctcatgcact gtgccaaaag taacggctat ttttgagact tccgccaaca
    10261 tttccccggc ctgacatcag atgtcgtcag atgtcatcaa atgtcatata aagcgctatt
    10321 taccaaatgg ttagtactat ctaattttgc aaaatcaaaa tccgtcaatg gaggggaaca
    10381 cgcttcgccg gaccacagca cgccgtgaac gtcgcgcagc aatccgacga aggaggattc
    10441 tctgttcaaa cgaacagagc aagttgtgtc cttgtccgac aaaaa
//
