LOCUS       c00536_gnlPro..         8672 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KHLFNIBO_536.
ACCESSION   c00536_gnlPro..
VERSION     c00536_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:54:10
            Original ID  :: gnl|Prokka|KHLFNIBO_536
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8672
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8672
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3002:8670]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3003..8670
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8672
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8672
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..457)
                     /locus_tag="ctg536_1"
                     /transl_table=11
                     /translation="MVYDLTMLEAFYSAYKGKVEHVRAVLKRPLTLAEKILYAHLFNEG
                     DLKNYKRGEDYVNFRPDRVAMQDATAQMALLQFMNAGKEKVAVPSTVHCDHLIQAYKGA
                     KEDIATATKTNEEVYDFLRDVSSRYGIGFWKPGAGIIHQVVLENYAFP"
     CDS             524..2470
                     /locus_tag="ctg536_2"
                     /transl_table=11
                     /translation="MKYIFVSGRRFITFASIMNNHPKSPIIDLQQQQLLLRMEYEHEKE
                     EFKRQTETMGVARKVKRGLCWYPASPGRSYYNSLNQLVIDITRTENKEIEHSFEFGRPV
                     CFFRQSFDGKVNYMNFIATVSYADDERMVVVLPSAGALLELQTEEVLGVQLYFDETSYR
                     AMFEALEDTIRAKGNRLAELRDTLLGTQKPGFRELYPVRFPWLNSTQETAVNKVLCTRD
                     VAIVHGPPGTGKTTTLVEAIYETLHREPQVLVCAQSNTAVDWICEKLVDRGVPVLRIGN
                     PTRVNDKMLSFTYERRFENHSAYPELWGIRKSIREMGSRMRRGSYSEREGMRSRMSRLR
                     DRATELEILINADLFDSARVIASTLVSSNHRLLNGRRFPTLFIDEAAQALEAACWIAIR
                     KADRVILAGDHCQLPPTIKCIEAARGGLDHTLMEKVVQQKPSAVSLLKVQYRMHEAIMR
                     FPSEWFYNGELEAAPEVRNRGILDFDTPMNWIDTSEMDFHEEFVGESFGRINKQEANLL
                     LQELEAYISRIGKARILDESIDFGLISPYKAQVQYLRSKIRGSSFLRPFRSLITVNTVD
                     GFQGQERDVVFISLVRANEDGQIGFLNDLRRMNVAITRARMKLVILGDATTLTKHAFYR
                     KLIQYIRQEAVSS"
     CDS             complement(3003..4046)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg536_3"
                     /sec_met_domain="IlvN (E-value: 2.3e-47, bitscore: 149.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.2e-40, bitscore: 128.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(4110..4853)
                     /locus_tag="ctg536_4"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEA
                     NENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             complement(4853..5416)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg536_5"
                     /sec_met_domain="ALS_ss_C (E-value: 3.8e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             complement(5435..7132)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg536_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.3e-47, bitscore:
                     149.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTQQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGAFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(7180..8670)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg536_7"
                     /sec_met_domain="ILVD_EDD (E-value: 1.3e-184, bitscore:
                     603.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPM
                     EAGEWNGQHLDLIDAMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAI
                     GLALPGNGTIVATHENRTKLFEDAAKLIVKNAMKYYEEGDESVLPRSIATRQAFLNAMT
                     LDIAMGGSTNTVLHLLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRA
                     GGIIAILAELAKGGLIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFN
                     LVLGSQGAYYQELDKDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIW
                     KFTGPAKVFDSQEAACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLG
                     KECALITDGRFSGGTSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEE
                     LAARPMTPVTRDRYVPKSLKAYASMVSSADKGAVRLID"
ORIGIN
        1 cggggaaagc gtaattttcg agtactacct ggtgaatgat tccggcgccc ggcttccaga
       61 agccgatgcc gtaacgagag gatacatcgc gcaaaaagtc gtaaacttct tcgtttgttt
      121 tggttgccgt agcaatgtcc tcctttgctc ctttgtacgc ctgtatcaag tggtcacagt
      181 gcacggtgga gggaacagcc actttttctt ttcctgcatt catgaattga agcaatgcca
      241 tctgggcagt cgcgtcctgc atagcgacgc ggtcgggacg gaaatttacg tagtcttcac
      301 cccgcttgta gtttttcaga tcgccctcat tgaacagatg ggcatacaga atcttctcgg
      361 ctaacgtcaa tgggcgtttc aaaacagccc gcacgtgttc cacttttcct ttataagcag
      421 aataaaaagc ctctaacata gtcaaatcat acaccatatt gcttttattt tttttagtct
      481 atctataaaa ataacgaacg gcgttcgagg aatgtttaac aaaatgaaat atattttcgt
      541 ctcaggaaga agatttatta cctttgcgtc tattatgaat aatcatccga aaagtccaat
      601 catcgacctt cagcaacagc aactcctgct acgcatggag tatgaacacg aaaaggagga
      661 attcaagcgg cagactgaaa caatgggtgt cgcccgcaaa gtgaaacgtg gtctgtgctg
      721 gtatcccgcc tctcccggtc gaagttacta taattctcta aatcaacttg taatagatat
      781 tacacgcacc gaaaataaag aaatcgagca ttccttcgaa ttcggtcgtc ccgtctgctt
      841 tttccggcag tcatttgacg gaaaagtgaa ttacatgaat ttcattgcaa cggtgagtta
      901 tgcggacgac gaacggatgg tggtcgtgct tcccagtgcg ggcgccttgc tggaactgca
      961 aacggaagag gtgctgggtg tacaacttta tttcgatgaa acgtcctatc gtgccatgtt
     1021 cgaagcgctg gaagacacaa tccgcgctaa gggcaaccgc cttgccgaac tccgggacac
     1081 cttgctggga acacaaaagc cgggattccg cgaattatat cccgtccgtt tcccgtggct
     1141 gaacagcacg caggaaacag ccgtaaacaa agtgttatgc acacgcgatg tcgccatcgt
     1201 tcacggccct ccgggaaccg gaaagactac cacgctcgtg gaagccattt acgaaacgct
     1261 tcaccgcgaa ccgcaggtgc tggtctgcgc ccaaagtaat acggctgtgg actggatttg
     1321 cgagaaactg gtagaccggg gtgtgcctgt cctccgcatt ggtaacccta cacgtgttaa
     1381 tgacaaaatg ctttctttca cttacgaacg ccgctttgag aatcattcgg cctaccccga
     1441 actttgggga atccgaaaat cgatccgtga aatgggcagc cggatgcgtc ggggaagtta
     1501 ctccgaaagg gaaggaatgc gcagccggat gagccgcctc cgcgaccgtg ccaccgaact
     1561 ggaaatcctg atcaacgccg atcttttcga cagtgcccgt gtgattgctt ccacgctggt
     1621 cagcagcaat caccgtttgc tcaacggacg gcgtttcccc accttattta tcgatgaagc
     1681 cgcccaggca ctcgaagccg cctgttggat cgccatccga aaggccgacc gtgtgattct
     1741 tgccggcgac cattgccagc tccctcctac aatcaaatgt atcgaagccg cccgtggcgg
     1801 actggaccac actctaatgg aaaaggtcgt gcagcaaaaa ccttctgccg tctcgctgct
     1861 caaagtgcaa taccggatgc acgaagcaat catgcgcttt ccctccgaat ggttctacaa
     1921 cggagaactg gaagccgcac cggaagtgcg caaccggggt atccttgact tcgacactcc
     1981 catgaactgg atagatacct cggaaatgga cttccacgaa gagtttgtag gcgagagctt
     2041 cggacgcatc aacaagcagg aagccaactt gttactgcaa gaactggaag cctatatcag
     2101 ccggatcggc aaagcacgca tcctggacga gagcatcgac tttggtctga tttcgcccta
     2161 caaggcgcaa gtgcaatacc tgagaagtaa aatcagagga agcagttttc tccgcccttt
     2221 ccgcagcctc atcacggtca acacggtaga cggctttcag ggacaggaac gggatgtcgt
     2281 ctttatcagc ctcgtccggg cgaacgagga cggacagatc ggttttctga atgatttaag
     2341 acgaatgaac gtagccatta cccgcgcccg gatgaaactt gtgattttgg gagatgcaac
     2401 cactcttacc aagcatgcgt tctaccggaa actgatacag tatatccggc aggaagcggt
     2461 atcctcctga atcatcggga taaaaaaaga agcccccttt ctcacgaaag aggactccca
     2521 tttacaaaca aaacaaacaa tgttattttc ccactaaatt ctgttccaaa agctctgtct
     2581 taaattcaat ttaacgcata ctttttcctg ctacagaata aaattctgca tcatatcaac
     2641 gaatcactaa tggaacacga aatataaaaa ggacttgaaa tggtattaca gctaccattc
     2701 ggtagagaat aacttaaata tcttttaatg taacattctg atatactatt tattaaagaa
     2761 gaaatcatct tcatacgtat cgatcttctg taagtaaaaa gtttcttcat tgcctattct
     2821 gttttatttg ttgccgtaaa ggtaatcata aatgctcttt ttcacctata ttatcagtat
     2881 cttttaatct ttttttctac tttcatcctt tttctattac tcaaaagacc ggtatctaca
     2941 tagaaaaagc gggaaaatac gcttttcccg ccttttgaaa aacttatata gtataagtct
     3001 gattaattat tttccggacg aagtttacga actgtcacgg cagtctgcca catttcgctt
     3061 tcgcgcaatg ctttcagttc ttcttccagt ttctcacgat aatccggttt ggagttagag
     3121 tcgattgaaa tctgtgcttc gttaccagtc ttcacactgt gatacaactt ttcaactacc
     3181 ggtttgatag catcgtggaa ggggcccatc cagtcgagag caccacgttg agctgtagta
     3241 gagcagttag catacatcca gtccataccg ttctttgcaa acaacggcat caatgactga
     3301 gtcagctctt ctacagtttc gttgaatgct tcggaaggag tatgaccgtt ttcacgcaat
     3361 acttcgtatt gtgccaacaa cagaccctgg atagctccca tcaatgaacc acgttcgcct
     3421 gtcaggtcgg aagtagcttc gcggatgaaa gttgtctcga acaaataacc ggaaccgata
     3481 ccgataccca atgcgattgt tctgtccata gcgttgcctg ttgcatcctg atagatagcg
     3541 taagaagagt tcaagccgcg accttcaagg aacatagtac gcaaggatgt acccgaacct
     3601 ttaggagcaa ccatgattac gtcgatatct gcaggaggaa ctacacctgt gcggtcactc
     3661 catgtaatag caaaaccatg agagaaataa agagcttttc ctgcagtcag gtaaggcttg
     3721 atagtaggcc atacagacat tactgctgca tcagacaaca ggcacataat gatcgtacct
     3781 ttttcgcaag cttcttcaat accgaacaaa gtttcacccg gaacccatcc gtcagcaacc
     3841 gctttgtcat atgtctttcc ctggcgttga ccaacgatta cattgaaacc gttatcacga
     3901 aggttcagag cctgtccggg accttgtacg ccataaccga ttacagcgat tgtttcattt
     3961 ttcaatactt cacgagcttt ttccaatgga aattcatcac ggataactac attttctaca
     4021 gttccgccaa aattcaactg tgccattttt tttgtttttt tgttttgatg acttgcgcca
     4081 tctgttatta attgatgtta tactctatat tattcaaata tcactttgga acggcatact
     4141 acctcgctgc cgtttttctt cacctctaca tgaaactcgt tttcattcgc ctcatcacag
     4201 aagaaagaga gttcatctcc gaaataactt tcagccacat acgccatttc aaaccggcgg
     4261 atacgtttcg tctgatacag ttctatcgga aacaagtcaa gtatgtgctc gatataacga
     4321 atactgttta cgtgtccgtt aatatcgata tcactgtatt ttgccgtcag cgtcgcaaca
     4381 ggctgattgc ttgtcacctt gatacgcgaa ggcttttcta tcgggcaagg ttcatcgcat
     4441 atataatcga cgatgcttcc tccatgcaat gccaacagat cggcaggctt acgggtattc
     4501 agattgatca tcgcccatac ggaacgggca tagccgatct tctttccatc cttgtcaatg
     4561 acggcaaagt tacggtcggt aaagagacga tagacattct ccacccatgt ctgaaccgag
     4621 aacttctcgt actggtaagg catctcatcc agctcgatag ccaggcggga aagcacccat
     4681 gtgtaattgt cctcgttcag cgtagcaata ccaaatccac ggtcgctggc atgaaaacct
     4741 gcgcaattca gcagatgatt tcccagcacg cccatggtca gacggccgtt aaaatctacg
     4801 tgaaacggct ctgccacaaa ctgataagtc cctattttat tttcttcact cattactcct
     4861 gttccttttt actttgctta tacttcgctt cctgtccgtc caggaactca ttcacacgtt
     4921 cgaaacagct ggtagtaata gccacacggc ccgaacggac aaactgcagc acacatttca
     4981 aagcccgaag ttcttcgtaa agggaagtaa tctcttcact catgccgttc ttctcgacga
     5041 tagagaatac cggattcacc tctacaatgc gggcattata tctgcggatc actttagatg
     5101 cttccggagt ctcctgaaaa gcaggagtag ataccttata taaggctatc tcatggaaat
     5161 aaatctcgtc ttccgtaaaa tagtgcgcct gaatcacatc aatcttcttt tcgatctgct
     5221 tcaccacctt ttcgatagtg tccttatcag tccacgctgt aatcgtatat ttatgtactc
     5281 ctttaatgga agaagcagaa acgttcaaac tctcgatgtt tatttgccga cgggtaaata
     5341 cagcggtcac ctgattcagc aatccggcta tattttcaga atgaactata atcgtatata
     5401 atgtcttatc actcataact ttctaaatta aggattaaca ttccagcaac atctgattga
     5461 ctgaaccgcc cggaggggtc atcgggagga cattgccttc ttctaccaca caggcttcga
     5521 gcaggaacgc cccgtctgtc gagagcattt cgtcgatggc cgctttcaat tcttcccgtg
     5581 aaaagacacg tttggaagga atatcgtagg cggaagcgat tttcatgtaa tccggattca
     5641 gcatcggagt aaatgaataa cggcgattaa agaacatagc ctgccattgg cgcacgttgc
     5701 cgagataatt gttgttcagg cagataatct tcaccggagc tttctgttcc atgatcgtac
     5761 ccagctcctg aatgttcatt tgcagtccgc cgtcacccat aaatacacat accgtgcggt
     5821 cgggacggcc gaaagtagct ccgatagctg ccggaaggcc aaaacccatc gtgccgagtc
     5881 cacccgaagt aacgatacta cgttccctgg tatatttaaa gtagcgggca gagatcatct
     5941 gattctgacc tacatctgtc accaatatgg cttcgtgacg ggtcgcttcg cttaccgcac
     6001 gcaccacttc gcccatactc agtgaatccg ttgcaggatg aagttcggga cgaatgactt
     6061 tttcttcctc taccgcttca tattccttga aactatcgac ccactcggtg tgccggttct
     6121 ttttcagcag tccggtcaca gcagccagcg tctttttgca gtcgcccaaa acggcaatgt
     6181 ctacctttac attcttattt acttccgccg gatcaatgtc aaaatggatc actttcgctt
     6241 gtttggcgta agtagccaga ttaccggtca cacggtcgtc gaaacgcata ccgacagcaa
     6301 tcagtacatc acatttgtta gtattgatat tcggtcccag atttccgtgc atacccagca
     6361 ttcctttatt caacggatgg tcggtaggca atgcggaaag tccgagcaag gtacaacctg
     6421 cgggcatatc cgccttttcg ataaagatac gcagttcttc ctgagcgctt cccagttcca
     6481 ctccctgtcc taccaagaca agcgggcgtt cggcgttatt gatcagttcg gcggcagcct
     6541 ttactgattc ttcgtctgta tcgggaaccg gaacatagct gcggataaac tcctgctgcg
     6601 tcggctcgta ttttgttttt tcaacctgcg cattcttggc aaagtcgagt accaccggac
     6661 cgggacgacc actactggca atgtagaaag cacgtgctat cgcccaggct acgtcttcgg
     6721 cacggcgaat ctgatagctc catttagcga ttggctgagt gatacctacg agatcgactt
     6781 cctgaaaagc gtctgttcca agaaagcctg ttcccacctg tcctgcaatg acaacgatag
     6841 gcgtactgtc tatcatcgca tctgcaatac ctgtgatcgt attggttgct ccggggccgc
     6901 ttgtcaccaa gcaaacaccg actttacccg atacacgggc gtagccttgt gccgcatggg
     6961 cagctccctg ttcatggcga accaagatat ggttcaatgt attttgatgg tcgtacaggg
     7021 catcgaacgt aggcatgatg gaaccgccgg gataaccgaa aatggtagtc actccctgat
     7081 gttccagaga gcgcatcatt gcctctgcgc ctgttattaa gtccttactc atagttcttt
     7141 aatggataat ggatgattca taatggataa tgaagtggat cagtctatta atctcactgc
     7201 tcccttatcg gcagagctta ccatgctggc gtatgctttc aggctcttcg gcacgtaacg
     7261 gtcacgggtg acgggagtca tcgggcgggc agccagttct tcatctgtta gtcgcacgtt
     7321 aatcgttcgg gcgggaatgt cgatttcgat gatatctcca tctactattt ttcctatatt
     7381 acctccggca gcggcttcgg gagaaacgtg tccgatactc aatccggaag ttccaccact
     7441 gaaacgtccg tcggtaatca aggcacattc tttgccgagg tgacgggatt tgatataaga
     7501 agtcgggtaa agcatttcct gcataccggg accgcccttc ggaccttcgt gcgtgatgac
     7561 gacaacgtcg ccgctgacga ctcggcctcc gaggatgcct tcacaggctg cttcttgtga
     7621 gtcgaatact ttggcaggtc cggtaaactt ccagatgctt tcgtctacac ccgccgtttt
     7681 tactacgcaa ccgtcctgag cgatatttcc tttcagtacc gccaggcctc cgtccttgct
     7741 ataggcgtgc tccagatcac ggatacatcc gttcgcgcga tctttatcta attcctgata
     7801 ataagctccc tgagaaccaa gtacgagatt gaatctgttt cctgccgcac ttgaatattt
     7861 gctcattgct ttttccgtaa cgttcgggct ggtaattgaa tattgatcga tcgcttccgc
     7921 cagcgacatg ccatccacac ggagaacgga agtatcaatc agaccgcctt ttgccaactc
     7981 tgccaggata gcaatgatgc cacccgcacg gttaacgtcc tgaatatgat atttttgagt
     8041 attcggagcg actttacaca ggcagggtgt cttgcgtgac agcatatcga tgtcgtccat
     8101 cttgaaatcg actcctgcct catgtgccac ggccaacagg tgaagcaccg tattggtaga
     8161 accgcccatc gcaatatcca gcgtcatggc attgaggaat gcctgacggg tagctatgct
     8221 gcgaggaagt acactttcgt caccttcttc ataatatttc attgcatttt tcacaatcag
     8281 tttggcagca tcttcaaaca gtttcgtacg attttcgtgc gtagccacga ttgtaccgtt
     8341 tcccggaaga gccaagccga tagcttcatt cagacagttc atcgagtttg ccgtaaacat
     8401 tccggaacaa catccgcagg taggacaggc attctgttcg atattcgcta cttcctgatc
     8461 gcttacactg tcgtccgccg atttaatcat ggcatcgatc aagtccagat gctgaccgtt
     8521 ccactctccg gcttccatcg gtccaccgga tacaaatacg gtagggatat tcaggcgcat
     8581 ggcagccatc agcatccctg gggtaatctt atcgcagttg ctgatacata ccattgcatc
     8641 cgccttgtgc gcattgacca tatattctac gc
//
