LOCUS       c00165_gnlPro..        11512 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJCOKJNE_165.
ACCESSION   c00165_gnlPro..
VERSION     c00165_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:58:46
            Original ID  :: gnl|Prokka|BJCOKJNE_165
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11512
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11512
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5243:9971]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5244..9971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..11512
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11512
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..820)
                     /locus_tag="ctg165_1"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFG"
     CDS             960..1145
                     /locus_tag="ctg165_2"
                     /transl_table=11
                     /translation="MVGDKVAKNKGVFFVIFATYPYQNTTWLYSIKNNRPLDWSKSSGY
                     FHLTKRSFYSTQKMFF"
     CDS             complement(1142..2695)
                     /locus_tag="ctg165_3"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             2894..3718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_4"
                     /sec_met_domain="GHMP_kinases_C (E-value: 8.1e-11,
                     bitscore: 32.3, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.9e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLCPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPANEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQGAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFRFKGRL"
     CDS             complement(3951..4985)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_5"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1e-52, bitscore:
                     169.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(5244..5816)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.9e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(5839..6405)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             complement(6441..7124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_8"
                     /sec_met_domain="FMN_bind (E-value: 1e-23, bitscore: 73.8,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             complement(7151..8077)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_9"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.1e-114,
                     bitscore: 370.5, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGVLIALIPAFLVSLYFFGLGALIVTATSVAACLFFEWAIVKFL
                     MKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGALFAIGVGKMSFGGLGCNPFNPA
                     LAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPLALMKQAIHGDASALSQIPDALT
                     LFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPVSIIVTVFVFAGIMHMVDPEKYV
                     SPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGVCIGLLTVVIRLFGAYPEGMSFA
                     ILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(8062..9084)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_10"
                     /sec_met_domain="SLBB (E-value: 7.1e-17, bitscore: 51.2,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.7e-51, bitscore:
                     164.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-06, bitscore: 18.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAKIDTVVDASGYAKPAIFIDVEGDEWEETIDRSKTLVKECELSS
                     EEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIINAVECEPYLTADHQLMLEHA
                     EEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASSYAGIEVVPLKVKYPQGGEK
                     QLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKNKPLFERVITVTGKSVTKPS
                     NFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVNIEVPTAKGSSGILIMNQKE
                     AKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETMEKERIMDCXXXXRKICMAC
                     "
     CDS             complement(9207..9971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.9; E-value:
                     3.2e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_11"
                     /sec_met_domain="Fer4_7 (E-value: 7.8e-13, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.7e-09, bitscore: 26.7,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.6e-09, bitscore: 25.9,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.5e-09, bitscore: 27.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 5.8e-09, bitscore: 26.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIAXXXXGFADACVKAGSLDGKFCPVGGQPVMA
                     QIADILGLAATEAEPMVAVVRCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCL
                     GCGDCVAACQFDAIHMNPETGLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYI
                     SCVNKDKGAVARKACTVSCIGCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCP
                     QNTIIELNFPPRKPKAEEAPKTVAAEAPKVTE"
     CDS             complement(9978..10403)
                     /locus_tag="ctg165_12"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDITDVTAASYQVGERVMVIGETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNEL
                     YAALLSLAVLIPYYFVLWLNKTRMKQHFSFTIKPINN"
     CDS             complement(10634..10726)
                     /locus_tag="ctg165_13"
                     /transl_table=11
                     /translation="MKKTWSVVLKVIIAVAGAIAGVLGVQAASL"
     CDS             complement(10762..11283)
                     /locus_tag="ctg165_14"
                     /transl_table=11
                     /translation="MSVIYKVVTRPSDPRVPNSPKKYYPHLITLGQSVNLKYIAQKMQG
                     YSSLSIGDIKSVIQNFVEKMKEQLLEGKSVNIEGLGVFMLTACSKGADAAKDVNAKSVD
                     SVRIFFQANKELRITKTATRADEKLDLISLDEYLKKLNASVTPNDPDDGENGGGGNEGG
                     GDEEAPDPTV"
     CDS             complement(11414..11512)
                     /locus_tag="ctg165_15"
                     /transl_table=11
                     /translation="SMVSITDMANVMVTAMDMAKIQKDKCLNIYEL"
ORIGIN
        1 gaccgaaagc atgaacgata taattagtaa tatccactac attattaata ggacgtacac
       61 cgatcaagcg caatttattc tgcaaccatt cggggctttc cttcacagta acgcctttca
      121 ccgtaacgcc ggcatagtga ggacaggctt cgctgttttc aaccactact tcgatatcca
      181 aatcatgatt ttccacctta aatccatcta cagatggacg ttgcaaagta gcctgcttgc
      241 cattctgaat caggtaagca tacaagtcgc gggccacacc atagtgtgag caagcgtctg
      301 cacggttagg agtaatatct acttcgagta cgtagtcact cttgatatta taatagtctt
      361 tggcgagagt acccggaaca gcttcagccg gcaacacgat gattcctgca tgatcagtac
      421 caataccgat ttcgtcttct gcacaaatca tccctgtaga ttctacacca cggatttttg
      481 acttcttgat agtaaagcat tcatcaccgt cataaagttt ggtacccaaa gtggcaacca
      541 ctactttctg tccggcagct acattcggag caccgcatac aatctgtaca ggttcgccgt
      601 ctcccagatt gacggtagtg atatgcaaat ggtcggaatt cggatgttct tcgcaagtca
      661 gcacttcacc gattacgagt ccttccaaac cacccttaat ggtttgcact tcttctacac
      721 cacctgtttc caagccgatt gaggtcagcg cagcagccgt ttcatcgggg gtcaaatcaa
      781 agttgacata ctctttcagc cagttataag agatattcat atatttaatt ttttattgtt
      841 tctcaaaaag attcgcaaag ttaataagat ttttcggttg acatagaacg atttgagaga
      901 aaaatgtcaa gagaagctaa actaacaagg acctgactgt attattcccc aataaattca
      961 tggttggtga caaagtggca aaaaacaaag gggtattctt tgtcattttt gccacctatc
     1021 cctatcagaa tacaacttgg ctatactcta taaaaaataa tcgaccgctc gattggagta
     1081 aatcgagcgg ttattttcat ctgactaagc ggtcattcta ttcaacccaa aagatgtttt
     1141 tttagaaagg taacggtcct tccgttgcac cgaacggatt atttccctgc ggaacaaagt
     1201 ccggttccgg cggaggcgga ggcatagcac cggcattcag tttagacccc agcatggcac
     1261 ctgcaggttc acccggcatc ggtataacca tatcatcttc cggattagag aatcgtgtaa
     1321 actcaccttt gaatcggagc aagacttcac ctaccgcacc attacgatgc ttggctatca
     1381 caatttccgc cataccgcgc aggtcgttac cacgatcatc ctgataaatc ttataatatt
     1441 ccggacggtg aataaaacac accatatcgg catcctgctc gatggctccg gattcacgaa
     1501 ggtcactcaa ctgagggcgt ttaccgtcaa taccttcacg actctccaca ccacgattca
     1561 actgcgacaa ggctataatg ggaatgttca actccttcgc caatcctttc aacgaacggg
     1621 atatcgtact aacctcttcc tgacggctac cgaatgccat accactcgca ttcatcaatt
     1681 gaaggtagtc aataataata attctcaccc catgttcacg caccagacga cgcgctttgg
     1741 tccggagttc aaacacagac aaagacggag tatcgtccac ataaagcgga gcatccagca
     1801 gatctttcag tttgtagtcc aactgttgcc actcatagct tgccaattgt ccacttttga
     1861 tcttctcact cggaatctca caaacattgg tgataagacg gttgaccaac tggacgttac
     1921 tcatttcaag agagaacaac gctaccggat tccgataatc aacagcaata tttttagcca
     1981 tagaaagtac gaaagctgtc ttacccatgg caggacgggc agcgattata ataaggtcgg
     2041 agttctgcca accggaggtc atcttgtcca gtttcgtaaa tccactttca agaccactca
     2101 gaccgtctgt tcgtgcagcc gctttctgaa tcagcttata cgcttcgtca attaccggat
     2161 taatctgcgt atagtctttc ttcatattct gctgggaaat ctcaaacaac ttaccttccg
     2221 cctcctgcat caagtcatcc acatccagtg tctcatcaaa agccttgctt tgaatattac
     2281 tggtaaacgt tatcaattcg cgcgccaacg atttttgtgc aataatacgg gcgtgatatt
     2341 cgatatgtgc ggaagaagca accttactgc tcaactgagt aatatagaac ggtccaccga
     2401 cctcttccaa ctcacctctt ttgctcaact gctctttgac cgtcagaatg tccaccggct
     2461 tctgattaac ggcaagatca gtaatggcag cataaatcaa ctgatgacga tgctcataaa
     2521 atgactccgg gcgaagaatc tcactcacca gcgaataagc atccttctca atcattaaag
     2581 cacccaacac cgcctcttcc agctccggtg cctgaggttg gatacgacca taatcattga
     2641 ccggttgtac tttagttgat tttgtgttac gggaatttct tctttgttca gccatctgct
     2701 tatatacaat tttatgattt acaatttatg atccccggct tttatacata gtaaaagccg
     2761 aaagggatga caaagataga atataataat gaagaaaaga taaggaaaaa tgaagatttt
     2821 agtaactttg tcaccaatag cataaattcg caacccataa tttaaaattc aaaaataata
     2881 attcagaacg aatatgatca ctttcccaaa cgcaaaaata aacctgggac tctctattac
     2941 cgagaagcgt ccggacggat atcacaacct cgaaaccgta ttctaccccg tcgctctcga
     3001 agatgcgctg gaaatccgga ccagccccga agcggacaaa aagttctccc tgcatcagta
     3061 cggaatggag atatccggta atccagaaga caatttagtg gtgaaagcat atctgctatt
     3121 agataaagag tttcacctct gtcctatcga gatccatctg tacaaacaca ttccttccgg
     3181 tgccggactg ggaggaggct catcagacgc ggctttcatg ctgaaattac tcaacgaaca
     3241 ctttcagctg aatttatccg aagatcagct ggaaatatat gccgcaactt tgggagcaga
     3301 ctgcgctttc tttatcagaa acgccccgac ctttgccgaa ggaatcggca acatattctc
     3361 ccccattcca ctatccttaa aaggatatca gattctgatc atcaaaccgg atgtattcgt
     3421 atcaacgcgg gaagctttcg ccaatattca tcctcatcat cccgaatact cgatcaaaga
     3481 agcgatcaaa cgcccggcaa atgaatggaa agagatatta atcaatgatt ttgaagacag
     3541 cgtattcccc cagcatccgg tgatcggaga aattaaagcc gaactataca ggcaaggggc
     3601 tgtttatgcc tctatgagcg gttccggttc ttccgtatat ggattgttcg agccggaagg
     3661 aactttacct gaaaccgatt ggggaactaa cgtattccgt tttaaaggca ggctgtaaag
     3721 gagtaacaaa aaacggtacc acgactcccg tcgtagtacc gtcacaacac aaacacaaaa
     3781 taaaacacga caaaactact atgcaatcat acctgtctat gccggagagg cataagtacc
     3841 atttactcat attcacatac tcacaaacag atcaagctga ttagcatcta ataaacaaat
     3901 cgcatgaacg atttgtttaa acttttatgt taattaaaac aaatatcttt ttactgaatg
     3961 cctctttcac ggagtttcag ctgccagttc catgcagagc gtaaagtatc ttctaatgtt
     4021 tctaccgctt tccaacccag ttcctggttg gcaaaatcgg ggttagccca taccttttca
     4081 atatcacctg cgcgacggcc tacaatctga taattcagtt taacgccggt agctttttca
     4141 aagccattaa tcagttccaa tactgaaaca ccgcgtcctg taccgatatt gaatacttct
     4201 actttttctt tctgtttttg ctccaaaata cggcggattg caatcacatg tgctttagcc
     4261 aagtcaacaa cattgataaa gtcacggata caagaaccgt caggagtatc ataatcgtca
     4321 ccgaatacac ttagtttttc acggataccc atcgctgtct gagtcagata aggaatcagg
     4381 ttttgaggaa caccgttcgg aagttcaccc agcaatgctg taggatgtgc gccaatcgga
     4441 ttgaaataac gcagcaaaat agcattgatc ggggctccgg aagctattgt atcacggata
     4501 atttcttcat taatctgttt tgtatttcca taaggagatt ccgctttctt gatcggagcc
     4561 ttttccgtta caggcaactc atccggttga ccatatactg tacaggaaga agagaacaca
     4621 atgccttcta ctccatgctt aggcattaac tccagaaggt tgatcaaaga aaccaggttg
     4681 ttacgataat aaagcaacgg cttctctacc gattctccta ctgctttgct tgctgcgaaa
     4741 tgaataatcg ctttaattcc tttatatttg gcaaatacgg catcaaggcc agcaaaatca
     4801 agacaatcca gtttctcaaa agctgggcgg ataccggata ctttctctat attgtcaaca
     4861 acgtcagcac tcgagtttga taaattatcg ataatgatta cttcgtatcc actgttttgt
     4921 agttctacaa cggtatgaga cccaatatag cctgttcctc ccgttactaa aattctttct
     4981 ttcatataat tttaaaatat ggttagtttt tcggttttca gtttgtttga ggtacaaatg
     5041 tatggaaata aaatggaaat gcaataaact atcgcaattt tattcacagg aagatactta
     5101 cgggacgatt tgatggcgtt ttggtatgat aaaaaacata ttcggtatga acagatataa
     5161 agaaaaaggc cggaaacaaa ctgcctgtat gttgccatac gacagagttt ccagcctctt
     5221 tatctaatta tcaacttagt cttttacacg acgccagaga agcccatgaa tgccattgcc
     5281 agcaaacctg cggtaatcaa agcaatcgga gtcccctgca ttcctttcgg aatcttcacc
     5341 agggtcatct gctcacgcaa tccggcaaac aataccagtg ccagaccaaa gccaagagca
     5401 gtagagaatg cgtatacaac acctgtcagc agatcaaagt ctttctggat taccaggatt
     5461 gccacaccga gaatacagca gttcgttgta atcaacggca ggaacacacc cagtgcctga
     5521 tacaaagaag gagaaacttt cttcagaata atttctacca tctgcaccag tccggcaata
     5581 accagaataa aagtgattgt ctgtaagtac cccaatccga aagcgtccaa cacaaacttc
     5641 tgaatcagga atgtgacgat ggtagcgata gtcagcacga aagcaactgc cgcactcata
     5701 cccatcgctg tttccacctt cttggaaaca cccaggaacg gacagattcc caggaactgc
     5761 gacaacacaa tgttgtttac aaagattgcc gagataaata tcaatatata ttccatattc
     5821 ttttcttatt taatagagtt aggctttctt cagactatta ataatggcaa tcagataacc
     5881 taaagcgata aaggcacccg gagccagaac aaagatcagc attccgtatt cttccggcag
     5941 aatggtcaga ttaaatatct tacctgttcc gaggaattca cgtacggcac ccaacagagt
     6001 cagggcaatg gtaaaaccaa atcccatacc gataccatca aacatagaag ccagcggatt
     6061 gttcttcgct gcgaaagctt ccgcacgtcc caatacgata caatttacta cgatcagcgg
     6121 aatgaaaaga ccgagagtag catacagatc gggcacgtat gcttgcatta tcatctgcaa
     6181 cagtgtcacg aatgacgcga tcaccacgat aaatgaaggg atgcgtacca tatccggaat
     6241 cagattcttg atagatgaaa ttaccacgtt cgagcaaatc aggacgaaca tagtggccag
     6301 tcccataccc ataccgttga ttgccgatga tgtcgtaccc agtgtaggac acataccgag
     6361 caggagcaca aaaataggat tctctttgat aatcccgttc atcattactt taaaattatt
     6421 cataactgtc tcctcctttc ttagttatta gtgtcattag cagctgcttc accttccggt
     6481 gcaacagccg gttcattttt ctgggaagct ccggaattcg tatccacctc accgccttta
     6541 tatgcctgat aagcagcatt caccgcattc aggaaagcac gtgaagtgat agtagaagcc
     6601 gtgatagcat ctacctgtcc attcatgtct ttggtcacag ccaatggagt ctctcccgga
     6661 ttcatgccca aaatagactt tgcactttct tcgtgagata ccggtttttc gttctttgca
     6721 ggatcataag ctccaaacca tttgtccgct ttcgaaccca atcccggagt ttcagcgtgc
     6781 gccaataaag agtagttata aatcttgcct tcagcatcaa agcccaccag cactttcagt
     6841 tcaccgccaa atcccattga cttggcttca acggcagaac ctacccactt ttcgccattc
     6901 ttggccggat agataatgaa atccacgatt ttctttccgt ctttctcgct gaaaacagta
     6961 tcgctttcgg ctaccggatt attggtatat tcaggaagca cctttttcaa ggcctcgttc
     7021 agcgtctttg cattcgcttc ggcaataggg cctttcgtca gttcgttcac ataagccagc
     7081 aacgctacgg aaacagctgt aacgcccgta agtaccagca acatattctt taaagatgat
     7141 tgtaactttt tcatttcttc ttcgctacct ccccaaagcg tttaggttta caataggtgt
     7201 taatcagcgg agtgaacgca ttcataatca ggatggcgaa tgacatacct tcgggatatg
     7261 caccgaacag acggataacc accgtcagca gaccgataca aacaccgtaa atcagcatac
     7321 ctttcttgct catcggagaa gtcacatagt cggttgccat aaagacagct cccagcatca
     7381 gacctccgga gagtagttgc aataccggag aaacatactt ttcgggatcc accatgtgca
     7441 taatgcctgc aaatacaaat acagtcacaa tgatagaaac cggaatatgc caggtgatga
     7501 tctttttcca gagcatgtat accagtccga gcaacagtgc cagcgcactt acttcaccga
     7561 tacatccgcc gttctgtccg ataaacagag tcagcgcatc aggtatctgg ctcaaagcac
     7621 ttgcatcgcc gtgaatagcc tgtttcatca atgccagcgg agtagcaccg gtggtagcgt
     7681 ccatataaga tgtcagctga cctactaccg gccatgttgt catctgcacc gggaaagaaa
     7741 gcaacaggaa tacacgtccc gccaatgccg ggttgaatgg gttgcagccc agaccaccga
     7801 aagacatctt gcctacaccg attgcgaaca gtgcacccag aatgataatc cagataggca
     7861 gattggaagg tagattgaat gccagcaaca cacctgtaat gacagcagaa ccgtcacaaa
     7921 tggttgtagc aggtttcttc attaagaatt taacgatcgc ccattcgaag aataaacagg
     7981 ctgctaccga agtagccgtg acaatcagag cccccaggcc gaagaaataa agcgacacca
     8041 gaaaagccgg aatcagtgcg atcagcacgc catacatatt tttctgtnnn nnnnnnnaca
     8101 atccatgatt ctttcttttt ccattgtttc aaaatctccg ttttcggaca aagctccgag
     8161 caagtacggc tccagtccca tcggacaagc gctcacacac tttgcgcaac ggatacaggt
     8221 ttgtgcttca ccacgtttgg cttccttctg attcataatc aggataccgg aactgccttt
     8281 tgcggtagga acttcgatat tcaccagagc cttacccatc atcggaccgc caccgatcac
     8341 ttttcccgta tcctccggca gaccgccaca agcatcaatc agctgtttca ttggtgtacc
     8401 gatacgagct aggaagttgg aaggtttggt cacagactta ccagttacgg taatcacacg
     8461 ctcaaacaac ggtttatttt tctgaacagc ttcataaaca gcaaatgccg tacccacatt
     8521 ctgcacaact gccccagtag agataggcag cgcaccactt gccacctggc gtttggtaat
     8581 cgcatcaatc aactgtttct caccaccctg aggatatttc actttcaaag gaacaacttc
     8641 gatgcctgca taactagaag caactttcgt catcagttca atagcatccg gcttgttatt
     8701 ctcaattccg ataaatgcct tatttacctt cacggctttc atcagaatgg agacacctac
     8761 catgacttct tccgcgtgtt ccagcatcag ctgatggtcg gcagtcagat acggttcaca
     8821 ttccaccgca ttgataatca cacattctgc cttgaacgaa ggaggcggac aaagtttcac
     8881 ctgtgtaggg aaacaagcac cacccaaacc tacgataccg gcatcggcaa tcttcttcac
     8941 gatttcttcg gacgaaagct cacattcttt gaccagtgtc ttgctacggt caatggtttc
     9001 ttcccattcg tcgccttcta catcaataaa aatagcaggt ttagcataac cgctcgcatc
     9061 gactactgta tcaatcttcg ccactttacc actgaccgaa gagtgaattg ctgccgaaac
     9121 annnnnnnnn ncaatttatt ttcgtgtgga tgaactccac caattgaaaa tgtctttaac
     9181 atacaattct gtattttatt ctgttattat tctgttacct tcggagcttc tgcagcaact
     9241 gttttcggtg cttcttccgc cttcggttta cgtggaggga agttcagctc gataattgtg
     9301 ttctgcggac aaacttccac gcacttacgg catgatttac acttgttcgg atcgatgtaa
     9361 gccaggttgt tctccagcgt aatggcttcg aacggacaag tcttgacaca cttaccacag
     9421 ccgatacagc tcactgtaca agccttacgt gctacggctc ccttgtcttt gttcacacaa
     9481 gagatgtaca cacggcgtga tttcttgcct tgcggacgaa tctcgatgat cgccttcgga
     9541 caagccttta cacaagcgcc acaagctgta catttggctt catccacttc cggaagtccc
     9601 gtttcaggat tcatgtggat agcgtcaaac tggcaggcag ccacacagtc gccacatccg
     9661 aggcatccgt agctacaacc tgtttctcca ccatacaatg aagcggcaat agcgcaactc
     9721 ttcgcaccgt cgtattgatt aatacgcgga cggttggcac agcttccgtt acatcttact
     9781 actgctacca tcggttcagc ttcagtagct gccagtccga gaatatcagc aatttgtgcc
     9841 atgacaggct gaccgcctac agggcagaat ttaccatcca gcgaaccggc tttgacgcaa
     9901 gcatcggcaa atccgnnnnn nnnnngcgct atagctccca atgaaatcac tgcaatcaga
     9961 atcaaattca taatgtttta gttatttatt ggttttatag taaatgaaaa atgttgtttc
    10021 attcgcgttt tattgagcca caatacgaaa taataaggaa taagaactgc cagagaaaga
    10081 agagccgcat acagttcatt ccctatcaac gccatccatg cgaacaggga aacaatcaga
    10141 agtacaaaag gaattatgaa tgcaagggtt acagccatca tgcccatcga cgtttcaccg
    10201 atcaccatca cccgctctcc tacctgatag gaagcagctg taacatccgt tatatctatg
    10261 attttgtctt tactatccgc cgaagaacag tggccttttg cgctacaagc cgcacaagcc
    10321 gacgtctgaa cgattctcac cgacagatga gaaccctgta tgttttccac aatacctaga
    10381 tgctttatag tattattcgt cattttgcaa actcaacatt acaaatcgcg gcaaatttaa
    10441 tcattatttg tgaactacga agcattccct catttttttc tacataataa aatgttattt
    10501 tttgtgtttt cgttatcgca cacgaaaaag taacgccaac tatttgatat tttagcatac
    10561 aacaaagcag gcgggaaagt tcttcccgcc tgcctgtctt atctaaccaa ttactttatt
    10621 tactgaatgc tgcttacaat gatgcagcct gtactcccag tactccggca atcgcaccgg
    10681 ctacagcaat gattactttc aaaactacac tccaagtttt cttcatagat ttttcctcct
    10741 ttctttttta agcttttcag attatacagt cggatccggg gcttcctcgt ctcctcctcc
    10801 ttcatttcca ccaccgccat tttcaccatc atccggatca ttcggagtca cagaggcgtt
    10861 caacttcttc agatattcat ccagactgat caaatccagt ttttcatctg cacgggtagc
    10921 cgtcttcgtg atacgcagtt ccttattcgc ctgaaagaag atgcgtacgc tatccacact
    10981 tttagcattg acgtctttcg ccgcatccgc ccctttcgag caggcagtca gcataaatac
    11041 acccaagcct tcgatattca cagacttacc ttccagaagt tgctctttca ttttctccac
    11101 aaaattctga atcacactct tgatatcacc aatggataaa gaagaatagc cctgcatttt
    11161 ctgcgcaata tatttcagat tgacagactg acctaaagtg atcagatgcg gataatattt
    11221 cttgggagaa ttgggaacac gcgggtcaga tggtcgcgta acaaccttgt aaattacact
    11281 cataatacgt tttttaaaga ttcaaattca agttatttta ttcacgtttt gttgatcaac
    11341 aatgcaaagg tgaggctttt atttcagata acaaaaagaa aagccccttg cggggctctt
    11401 tttctgagaa aagttataat tcatagatat tcagacattt atctttttgt atcttggcca
    11461 tatccatagc cgtaaccata acgtttgcca tatccgtaat gcttaccata ct
//
