LOCUS       gnlProkkaPMGIMJII_215  30610 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PMGIMJII_215.
ACCESSION   gnlProkkaPMGIMJII_215
VERSION     gnlProkkaPMGIMJII_215
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:23:39
            Original ID  :: gnl|Prokka|PMGIMJII_215
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1402
            Orig. end    :: 32012
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..30610
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:27596]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27596
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..30610
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..30610
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(1736..3343)
                     /locus_tag="ctg215_4"
                     /transl_table=11
                     /translation="MNHKWNYQPKKFFRPQLPDLHDPFLMKDMDIAVERLNKAMGKKER
                     ILIYGDYDVDGTTAVALVYKFIQQFYSNIDYYIPDRYNEGYGISKKGVDYASETGVGLI
                     IVLDCGIKAVEEITYAKEKGIDFIICDHHVPDDILPPAVAILNAKRLDNTYPYTHLSGC
                     GVGFKFMQAFAINNGIEFHHLIPLLDLVAVSIASDIVPIMGENRILAYHGLKQLNSNPS
                     VGMKAIIDVCGLSEKEITVSDIVFKIGPRINASGRIQNGKEAVDLLTEKDFSAALEKAG
                     QINQYNETRKDLDKSMTEEANNIVANLEGLSERRSIVLYNEEWHKGVIGIVASRLTEVY
                     YRPAVVLTRTDDMATGSARSVSGFDVYKAIEHCRDLLENFGGHTYAAGLSMKVENVEAF
                     TRRFEEYVSQHILPEQTSAVINIDAEIDFRDITSKFFNDLKKFNPFGPDNIKPIFCTHH
                     VYDYGTSKVVGRDQEHIKLELVDNKSNNVMNGIAFGQSSHVRYIKTKRSFDICYTIEEN
                     THKRGEVQLQIEDIKPIE"
     CDS             4394..5062
                     /locus_tag="ctg215_5"
                     /transl_table=11
                     /translation="MEINPKTGKKIGIAFTGQLEKISRIARKHQAIGAINGSYFDMTKG
                     NSVCFLKVGSQVVDTTSLDELKLRVTGAVYEKKGKVKLIPWDRQIEKNYKKNKGSVLAS
                     GPLMLKDGEYYDWSQCNANFIETKHPRSAICLTEEGKILFVTVDGRSPENAVGINIPEL
                     AHLLHVLGGKDALNLDGGGSTALWLSGAPEEGIVNFPCDNRNYDHQGERKVANFLYVHD
                     "
     CDS             complement(5164..5847)
                     /locus_tag="ctg215_6"
                     /transl_table=11
                     /translation="MKKILLLFILLVSVSIYCDAQNYSEVVYLKNGSVIRGLIVEQIPD
                     VSIKIKTYDGSLIICRMDEVLRIENGRLYKKYYNPTQSTLKGYKGFVDFGYVVDVSGHH
                     ASKIELSTSHGYQFNNYFFLGGGVAVSHFTDASLTTVPFFINFRANFINRPITPFMELR
                     TGYSAGDIEGLYSTLGAGVRFALRNKMALNLKLEYNLQEYDIPDYYWDSSYDLHGIGIK
                     IGFEF"
     CDS             complement(5869..6438)
                     /locus_tag="ctg215_7"
                     /transl_table=11
                     /translation="MKKLILFLFLSISLFSFGQGSSATKDIQSIKFYGVDYSQAKVFGA
                     KESPYEFKLAFRRINELFIAEAKKYDVGKQLKKEVSEISLEAVNKVNEAINPDELFTSR
                     TQYTLTKEQVNAAIQALPIPKEAGVGMVFIAEFLNKAASRGTYQVVFFDTDTKEIIEEW
                     STDGKAGGFGLRNYWAGSIHNAIKHL"
     CDS             6467..6859
                     /locus_tag="ctg215_8"
                     /transl_table=11
                     /translation="MCCLLLEFEADFHANGIQCLIFVGIAKPVGNDQFIVSLTGKFDFE
                     IECHFSFQRDTQPCCQRNIDSGDISGGVSESDIGKWSKFLIEKVGTEVCEYRYSCTLCI
                     IVSVQCHTASDIEMIVELEAVGGRQL"
     CDS             complement(7250..8545)
                     /NRPS_PKS="Domain: AMP-binding (49-290). E-value: 1.5e-14.
                     Score: 45.2. Matches aSDomain:
                     nrpspksdomains_ctg215_9_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_9"
                     /sec_met_domain="AMP-binding (E-value: 6.4e-14, bitscore:
                     42.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEEIKCYQEEQLAKALAYLQANSKFYQQMFEEHH
                     IDINQIKKIEDLQQIPVTTKTDLQLHNDDFICVDREEIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCTKQDVLQLMTTIDRRFMAGLAYYMGARELGMGVIRVGNGIP
                     ELQWDTIRRIHPTWGMVVPSFLIKLIEFAEKNHIDHNECSMQKCICIGEALRNQDFQLN
                     TLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIVEFLDDDNRPVAEG
                     EAGEVTITTLGVKGMPLLRFKTGDICYHHTEPCACGRNTIRLSSILGRKGQMIKYKGTT
                     LYPPALFDILDNIPSVKNYIVEVYTNELGTDEILIRIGSENRSESFAKEIKDLFRSKVR
                     VAPTINFESAEYIAKIQMPPMSRKSIKFIDLR"
     aSDomain        complement(7676..8398)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_9_AMP-binding.1"
                     /evalue="1.50E-14"
                     /label="ctg215_9_AMP-binding.1"
                     /locus_tag="ctg215_9"
                     /protein_end="290"
                     /protein_start="49"
                     /score="45.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QIKKIEDLQQIPVTTKTDLQLHNDDFICVDREEIIDYVTTSGTLG
                     DPVTFVLTSEDLDRLSYNEYLSFTTTGCTKQDVLQLMTTIDRRFMAGLAYYMGARELGM
                     GVIRVGNGIPELQWDTIRRIHPTWGMVVPSFLIKLIEFAEKNHIDHNECSMQKCICIGE
                     ALRNQDFQLNTLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIVEFL
                     DDDNRPVAEGEAGEVTITT"
     CDS             complement(8547..10220)
                     /locus_tag="ctg215_10"
                     /transl_table=11
                     /translation="MRKGIKTTIKYATGILLLLIVVLMGGVCYLYFSADMLTPAYTPTA
                     SAEKVLRTDSLRQYGDNYLRHSQSGLWELKIKGNAFQRGEAIGKLSPDLLYYQEKVFVD
                     QIREIIPSESYLKFLRFFIVLFNRELGKNVAEEFRDEIYGISLSCTHEYDFIGTPYERQ
                     LNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDFYVGDAFAHNKLVSFY
                     EPEQGYKFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSATPISILTREILQYAS
                     TIEEAYAIAQKRQTFVSESILIGSAKDGKAAIIEKSPEKTVLFAGEEKDRIICTNHYQS
                     EAFSKDERNMENIHTSDSPYRFARLKELINEKLPIDVTKAASILRNHKGLQNTDLGLAN
                     EMAINQFIAHHSVIFQPERRIMWVSTSPWQCGKYVAYDLNKIFSDSIDFLREISEPEQT
                     IPADTFMEQPEFKQLLTYKKLTPLLLKKIRRKEKVEDSVLKRYEASNPSLYFVYEVLGD
                     YYEAIRQPQQAVGYWKKALNRPIPKLQEKERIQQKIQKQS"
     CDS             complement(10213..11703)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 153.8; E-value: 1.4e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_11"
                     /transl_table=11
                     /translation="MSKYDIIIIGSGLGGLECGAILSKEGFNVCVVEKNAQFGGCFQTY
                     QRKENLFDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKVRRLDDTAFDTIYYKGKSYDYA
                     MGYPQFIETLCQSFPHEKEHLKRYAAELQAVGNLISVDHLKQGTIALEGMKYFCTSAAG
                     LIADIIPDPTLQNVLAGSALLYGGLKDVSTFYQHAMINHSYIEGAYRFVDGSMQVSLEL
                     INVIQKNGGTVLNNSEVTRIIVENEKVQGVIINGEERLESESVISGIHPKRMLEILDKS
                     RSIKNAYISRISSLENTYGIFTLYLVMKKKSLPYQNRNLYLHGDNEVWYDKQQYPGQTT
                     NCMISMQASSEDSQYAGIVSILTPMYMNELSEWKDTAPERRGESYRKFKREKAQQILRF
                     IQEHGIDFSDCIEEIHTTTPLSYRDYTGTEEGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     LTGQNLNVHGALGVTLTAMLTCAEFVGQEYLAKKVGNA"
     CDS             complement(11690..15562)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     44.1; E-value: 1.3e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_12"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLICCVLLMGFFALQVRFEENVTQ
                     FFPDTKDSQNAIKVFDNLKIKDKIIIMLSAADTDSIVEPDSLIEAADQLQQTLTDKAGD
                     KLIKEIFAQVDQSLIGGATDFVYDHLPLFLSDADYQRLDSLLTKEGIQAIMQQNYTRLL
                     SPAGIALRSYILRDPLGLGNEALKHLQDFQLEANYEINEEHIFSQDGSTLLMFITPVFS
                     TGSTGKNDELVRILEEELQQVQKQHPTLRAEYFGGPSVGVYNARQIKQDTILTSSIALV
                     IIIVFISLVFKRKRSIPLIITPILFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFLGLVFTSSDLLRDFGLFASLALI
                     GTTLFCLIYLPHFLKGQADVKQGRVLRLIEKINAYPFEKNKWLVGSILVITVICLFTSQ
                     KVGFNNDMMSLNFEPPHLKQSGEKLMQLFDNHEKTVLFVSVGKDMNRATETYAETNRKL
                     AALKEQGLIKDYASASQFLISPQEQQKRLEKWQSYWTNDRKKQVYEDLETAAAGYRFRP
                     GSFDSFRQWLDSSFHEYVYNAQSEDLSGKLLNEWQTSADSITMLISQVRVNETAKEAVY
                     EQFSKEKDVVIFDRSYFTNKWVSAVNNDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLVSWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGKKVLNS
                     HKTAIFFSAFTTVVGMGALVFARHPALQSISLISILGMMAVVLVAYTIQPLIFRFFISG
                     PASKGLPPYTVIGLMRTVILFLLFFFGCILLRLLIIVLYPIPVRKSSKQHLVCKLIQIT
                     CKGILLVATSVKKEHINKTNERFDRPAIIIANHQSFIDILVLLSLSSKIVMVTNHWVWH
                     SPFFGAIIRYADFYYIGEGYEQYVERMRKKVQEGYSIAIFPEGTRTYNGKMKRFHKGAF
                     YLAETLQLDILPILLYGNNRIIAKAQPFNIRKGIIYTEILPRIPVDDLSFGVTYQERTK
                     RISAYMRQEYARICREKNTTDNPAFYEALIQNYIYKGPVEEWYVRIKVKMEKNYRLFNQ
                     IIPVKGQITDIGCGFGPLCYTLSLLSEEREILGIDYDEDKIAVAQHGWLRNERLRFEYG
                     NALQYPLPESDVFILNDMLHYMSYEHQRTLLLKCAALLRPQGMIIIRDGNSANTSKHRL
                     TRLTELLSTRIFNFNRTTEKLCFTTEAQLREMAATFGMNIEIIPNDKYTSNTIYIFRKP
                     DSHEQI"
     CDS             complement(15559..16749)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 78.4; E-value: 1.1e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_13"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-28,
                     bitscore: 91.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQRCTAYWHETLKQLGIIVIIPSYNNGKTLAAVIESVQFYAPD
                     ILVVNDGSTDETAGILNRYTEIQVITHPVNKGKGTALKHGLCHAKGQGYRYAITIDSDG
                     QHFASDIPEFIEAIEKEQDTLLVGARNLASDNMPGKNTFANKFSNFWFTLETRIKLEDT
                     QSGYRLYPLQRMNVDRWYYTAKYEFELEALVFAAWGGIAVKNIPVHVYYPPQEERVSHF
                     RPFQDFTRISILNTILVLITFLWIIPRNFFRKLTWQNCKKFFSDHVTHSPESNLRITST
                     IMLGVFMGIVPVWGYQMLITLFLAHLLRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGKPINLQLNELSFENVKSVIEQYLIGSVIFAVVCSVVAGIVALVLLTACRRKKI"
     CDS             complement(16746..17120)
                     /locus_tag="ctg215_14"
                     /transl_table=11
                     /translation="MLLDNFYTILSSEQPDETSGTVLLELNPDHAIYQGHFPAHPVVPG
                     VCLLQLIKESVENIRHQKMQYTQISSCKFLSAINPTDTPRISLTWSVKETEDHNLQLQA
                     EGIAKDEPFIKLKAVLTPQL"
     CDS             complement(17122..17580)
                     /locus_tag="ctg215_15"
                     /transl_table=11
                     /translation="MPPAIELTAGKGSQKYNIQLDFMKHHLSGMLIVRRMPENEIRILA
                     STYFGLSLFDFSLRGENFLVNSCVAPMQKEKVLKLLEMDFKHLFLSSKGIRVRTSKDGA
                     IEKRTSGKGFGKSIVSITGETQGDPEQVRIRHPWIRLTIQLDKLPKDN"
     CDS             complement(17657..18292)
                     /locus_tag="ctg215_16"
                     /transl_table=11
                     /translation="MRTLSTYLLLSFLSIASVSSQTMKKMTQLQEFESRLAKEAQTVQS
                     IESDFTQVKYLDVFDEKVTSKGKFSYQKSNKICMEYFRPMDYLIVINGNKLKIVSDGKK
                     SIMNLSSNKMMNQMQDMLTACMIGDLSKMSSSYQLEYFEDAHYYLVKIKPTNKAVQAYI
                     NGIEIWLDKKDMSVYKLRLSETATNYTEYEFYHKKFNSLKDETKFAVR"
     CDS             complement(18304..18984)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 128.2;
                     E-value: 6.7e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_17"
                     /transl_table=11
                     /translation="MIIGCLVLCLLLILSALVYASYSIKAGIYLRSFCQKQTAEKIVSL
                     TFDDGPDSVQTPKVLEVLKAYQVNTCFFCIGKQIKGNEKLLQQMIAEGHLIGNHSYTHS
                     ALFPVYPLSKMKKDLQTCQSELEQVTSQPVTLFRPPFGVTNPTIAKAVRQLGYTSIGWN
                     IRTLDTQQHAPEQILRRIRKRLTPGSVILLHDRMPDSDLLVKQILDLLKEQEYTVVRLD
                     KLWT"
     CDS             complement(18981..19997)
                     /locus_tag="ctg215_18"
                     /transl_table=11
                     /translation="MQPVYIQHTASVHPQGNPENHPYLSACEPDYKVIITNTTLRRRMS
                     RIIKMGVACGLECIADIAPEKMQGIITATGLGCLSDTEKFLNTLIDNEERMLNPTPFIQ
                     STFNTIGAQIALLRQIHAYNMTYVHRGLSFESALLDAMMKIEEGSENILVGAVDEITDS
                     SYIIQQRLGLLKGTQAGEGAQFFLLSREAGSHSLAEIRGVETYAGKQTAEEISSRISRF
                     LQRYGLEPQDIHWLITGKTGPTDKTDTVITEENRFSLQDGSIKGENEIYKKLETELFPN
                     SLSLSFKDECGEYPTASSYAVWKAVKELASCNDTVNLLIYNHHHSINHSLMLIRKSV"
     CDS             complement(20001..21227)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (75-396). E-value:
                     1.3e-39. Score: 128.1. Matches aSDomain:
                     nrpspksdomains_ctg215_19_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 265.1; E-value:
                     2e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_19"
                     /sec_met_domain="APE_KS2 (E-value: 2.5e-124, bitscore:
                     406.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVISGIGIGVSENIEALKQKRHGIGKVTLFPTALDVP
                     VSEVKCDNEKLKQLLSLSPLQTVSRTALLGMMAAKEALEDAGLPMQGTRNTPQQQPLRI
                     GFISATSVGGMDLSEHFYEAFKQDPSRGQLREVISHDCGASTELIASYLGIRDFVTTIS
                     TACSSAANAVILGARMIRHGQLDAAIVGGTDALCRFTLNGFHSLMILDKDHCRPFDRSR
                     AGLNLGEGAGYLVLQSEKSLQRTPYCELSGFANTNEAFHQTGSSPEGDGAFSSMSEAIA
                     SSGVSAEEIDYINVHGTGTPGNDASEGTALRRIFGKAVPPFSSVKAFIGHTLGASEGIE
                     AVYSVLSIYKGMVYPNLNFTEPMSETGLVPETSFREGLPIRHVLSNSFGFGGNDSSLLF
                     SVVNEPLSI"
     aSDomain        complement(20040..21002)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_19_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.30E-39"
                     /label="ctg215_19_PKS_KS.1"
                     /locus_tag="ctg215_19"
                     /protein_end="396"
                     /protein_start="75"
                     /score="128.1"
                     /tool="antismash"
                     /translation="MMAAKEALEDAGLPMQGTRNTPQQQPLRIGFISATSVGGMDLSEH
                     FYEAFKQDPSRGQLREVISHDCGASTELIASYLGIRDFVTTISTACSSAANAVILGARM
                     IRHGQLDAAIVGGTDALCRFTLNGFHSLMILDKDHCRPFDRSRAGLNLGEGAGYLVLQS
                     EKSLQRTPYCELSGFANTNEAFHQTGSSPEGDGAFSSMSEAIASSGVSAEEIDYINVHG
                     TGTPGNDASEGTALRRIFGKAVPPFSSVKAFIGHTLGASEGIEAVYSVLSIYKGMVYPN
                     LNFTEPMSETGLVPETSFREGLPIRHVLSNSFGFGGNDSS"
     CDS             complement(21231..21515)
                     /NRPS_PKS="Domain: PP-binding (23-87). E-value: 9.6e-12.
                     Score: 37.2. Matches aSDomain:
                     nrpspksdomains_ctg215_20_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_20"
                     /sec_met_domain="PP-binding (E-value: 5.1e-12, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEFTSEKERELRDEVKGKLIEELNLEEITPEDIDDEAPLFGDEG
                     LGLDSIDALEIILILEREYGIKIENPGKGKEIFYSVRTLADYITANRKK"
     aSDomain        complement(21255..21446)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_20_PP-binding.1"
                     /evalue="9.60E-12"
                     /label="ctg215_20_PP-binding.1"
                     /locus_tag="ctg215_20"
                     /protein_end="87"
                     /protein_start="23"
                     /score="37.2"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     ENPGKGKEIFYSVRTLADY"
     CDS             complement(21512..23245)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (127-377). E-value:
                     1e-28. Score: 92.3. Matches aSDomain:
                     nrpspksdomains_ctg215_21_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 169; E-value:
                     2.8e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_21"
                     /sec_met_domain="APE_KS2 (E-value: 6.1e-106, bitscore:
                     345.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHPLNIYITAHTLISSLGFGTEENLKAIRTYRSGVHLQEAGPDS
                     EGNRISDTPIQAGLIDSAELEKRARQAQIEAYPRLEQLFILTIQEILSQSGADLCKQDC
                     ALLLSTTKGNIDLLGDSPVFLGKMAERIGSFFRTANRVEVISNACISGVSALIVAKRWI
                     ETGRYKQVIVAGGDILSHFITSGFLSFRSVSAQRCRPYDKQRDGLNLGEACGAVLLSTA
                     GSAKDILLSGGAVSNDANHISGPSRTGDGLALAISQAMKEAGVTPEDISFINAHGTATI
                     YNDEMESKAIHLAGLSSVPVNSLKPYVGHTLGASGIIESILCIEQLKEGIMYGTLGYET
                     PGVPMPVIVNAAHQSIAMKSCIKTASGFGGCNAAIVLSLPAYQKQGQSCVIQPITTCQT
                     VSIKRGTVKLAGKTIFSSQETEFAPFIREAYKSLGENNMKFYKMDDLCKLGYVAAGYLL
                     KDTAYQPEKIAILLANTSSSLDTDCKHQAIISKDGDASASPAVFVYTLPNVVLGEICIR
                     HKIQGENTFFVSQNYDEALLEDYARIVMAKGKLQTCIIGWCELFDGHYHAEFKQLIYQH
                     P"
     aSDomain        complement(22115..22864)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_21_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.00E-28"
                     /label="ctg215_21_PKS_KS.1"
                     /locus_tag="ctg215_21"
                     /protein_end="377"
                     /protein_start="127"
                     /score="92.3"
                     /tool="antismash"
                     /translation="MAERIGSFFRTANRVEVISNACISGVSALIVAKRWIETGRYKQVI
                     VAGGDILSHFITSGFLSFRSVSAQRCRPYDKQRDGLNLGEACGAVLLSTAGSAKDILLS
                     GGAVSNDANHISGPSRTGDGLALAISQAMKEAGVTPEDISFINAHGTATIYNDEMESKA
                     IHLAGLSSVPVNSLKPYVGHTLGASGIIESILCIEQLKEGIMYGTLGYETPGVPMPVIV
                     NAAHQSIAMKSCIKTASGFGGCNAAIVL"
     CDS             complement(23230..23703)
                     /locus_tag="ctg215_22"
                     /transl_table=11
                     /translation="MPDENIYKERMKRKTNQHSAALTNRTTLRVRFSEIDSMQIVWHGE
                     YVRYFEDGREAFGRQYGLDYMSIYREGYMVPIVDLTCQFKQSLSFGEEAIIETRYIACD
                     AAKIHFEYVIYRATDQSVVATGSTIQVFLNLNKELELVNPPFYTEWKKKWNIL"
     CDS             complement(23670..24116)
                     /locus_tag="ctg215_23"
                     /transl_table=11
                     /translation="MQIEMNKEATIHGEGILGLIPQRPPIVMVDCFFGIEENRSYSGLT
                     VTADNIFCEAGKLQEAGLIEHIAQSAAARIGFLYTQQGKEVPLGFIGSVDKLKIYSLPD
                     VGQKLLTEITVVQEVFDITLISAQVKADEELTTECRMKIFIKKE"
     CDS             complement(24101..25171)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 135.3; E-value:
                     4.7e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_24"
                     /transl_table=11
                     /translation="MQQNRYDKEPMTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADRREGLTQEEISKACGLSSYAVQVLLEASLTIGTVLLCEGHYQLAKAGWFLLNDKMVR
                     VNMDFNHDVNYLGMFHLEEALTEGRPEGLKVFGEWSTIYEGLSSLPTQVQKSWFGFDHY
                     YSDCSFDEALSIVFARHPKTLLDVGGNTGRWATRCVSYSPTVEVTIMDLPQQLEMMRQQ
                     TKELPEAARIHGHGANLLDPAVPFPTGFDAIWMSQFLDCFSEEEVTSILTRAARSMNKE
                     GRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMKRCIEAAGLEIEEI
                     HDHLGMGHSIVQCRLK"
     CDS             complement(25182..26093)
                     /locus_tag="ctg215_25"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYGFLSLVVLYFIPFA
                     PKATKSTWFYARHILKYSRLRSFGMLLRNYYRLGQILIDKVAIANGKVKKYRFEFERYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRKIKEMLEKNGQDK
                     EYKIIPVNEDNLTHVFRITEALDKKEYVCFQGDRYLNKEKLLTGCLLGEEAPFPAGPFL
                     LASRMKVPVVFYFAMREPGRTYRFHFFVAEPVTRSKENKAETALLEQYTATLEHILKRY
                     PEQWFNYYSFWKPATKQATDSI"
     CDS             complement(26098..26349)
                     /NRPS_PKS="Domain: PP-binding (8-75). E-value: 6.3e-13.
                     Score: 41.0. Matches aSDomain:
                     nrpspksdomains_ctg215_26_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_26"
                     /sec_met_domain="PP-binding (E-value: 3.4e-13, bitscore:
                     41.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRITLAEEFEVDIEVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        complement(26125..26325)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_26_PP-binding.1"
                     /evalue="6.30E-13"
                     /label="ctg215_26_PP-binding.1"
                     /locus_tag="ctg215_26"
                     /protein_end="75"
                     /protein_start="8"
                     /score="41.0"
                     /tool="antismash"
                     /translation="KIRITLAEEFEVDIEVIQPDAPLMETLELDSLDLVDMVVLVEKNF
                     GFNVTGQDFAGIKTFQDFYDLV"
     CDS             complement(26373..27596)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (61-404). E-value:
                     4.2e-52. Score: 169.3. Matches aSDomain:
                     nrpspksdomains_ctg215_27_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 294; E-value:
                     3.2e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_27"
                     /sec_met_domain="APE_KS1 (E-value: 6.5e-158, bitscore:
                     516.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPELKKLLDRRKRLCLPEQGEYAYLSTLEAFRNAGIDEAFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPKKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDARIALDRIAYINAHATSTPVGDLNEAKAIAEVFEGHRPYVTSTKSMTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPAQRVDMEFDTFLSNSFGFGGTNST
                     LILRKINE"
     aSDomain        complement(26385..27413)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_27_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.20E-52"
                     /label="ctg215_27_PKS_KS.1"
                     /locus_tag="ctg215_27"
                     /protein_end="404"
                     /protein_start="61"
                     /score="169.3"
                     /tool="antismash"
                     /translation="DRRKRLCLPEQGEYAYLSTLEAFRNAGIDEAFLEANEVGILYGND
                     SSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASG
                     SHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPKKASKPFDKRR
                     DGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAI
                     KDARIALDRIAYINAHATSTPVGDLNEAKAIAEVFEGHRPYVTSTKSMTGHEMWMAGAS
                     EVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPAQRVDMEFDTFLSNSFGFGGTNSTLI
                     LRK"
     CDS             complement(27622..28350)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 2.2e-14. Score:
                     45.6. Matches aSDomain: nrpspksdomains_ctg215_28_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     214.9; E-value: 2.2e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_28"
                     /sec_met_domain="adh_short (E-value: 9.8e-35, bitscore:
                     111.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRSVSCKLAEMGYFILINYQSNDTEAGKTLQL
                     VREKGSDGELMKFDVTDPAAIADALGEWNARHPDEYIEVLVNNAGIRKDNLMLWMTGEE
                     WSKVLDISLNGFFYVTQPLLKNMLVKRYGRIINIVSLSGIQGMAGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTPEEVAELVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        complement(27844..28341)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg215_28_PKS_KR.1"
                     /evalue="2.20E-14"
                     /label="ctg215_28_PKS_KR.1"
                     /locus_tag="ctg215_28"
                     /protein_end="169"
                     /protein_start="3"
                     /score="45.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRSVSCKLAEMGYFILINYQSNDTEAGKTLQLVRE
                     KGSDGELMKFDVTDPAAIADALGEWNARHPDEYIEVLVNNAGIRKDNLMLWMTGEEWSK
                     VLDISLNGFFYVTQPLLKNMLVKRYGRIINIVSLSGIQGMAGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       complement(28276..28338)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg215_28_0001"
                     /evalue="1.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg215_28"
                     /protein_end="25"
                     /protein_start="4"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRSVSCKLAEMG"
     CDS             complement(28352..29875)
                     /locus_tag="ctg215_29"
                     /transl_table=11
                     /translation="MTADKSINLDTLYKVLFENERLDLSEECIRKVEESFHFLQSFSSD
                     KIIYGINTGFGPMAQYRIEDQSLIDLQYNIIRSHSTGAGEPLPELYVKAAMIARLYTFL
                     QGKSGVHMELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVFYQGW
                     LRNAADVLRENNLKPFTMRIREGLSVTNGTSVMTGIGIVNLIYARNLLHWSVAASVIMN
                     EIAASYDDLMSQALNEAKHHKGQQEIAAMMRDWVAGSQCVRKRENELYNQIHTEKIFER
                     KVQAYYSLRCVPQVLGPVYDELENAEKVLINEINSACDNPIVDPETQNIYHGGNFHGDY
                     ISFEMDKLKIAVTKLTMLCERQINYLFHDRINSILPPFVNLGVLGLNYGLQASQFTATS
                     TTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKKVIENSYQVMAIQFMGIVQAI
                     DYLKIQEQLSPKSRRVYKEIRSFFPVFTEDTPKYKEIERMISYLKKENK"
     CDS             30215..30610
                     /locus_tag="ctg215_30"
                     /transl_table=11
                     /translation="MKAFGSNFRNGGLYGNMIGCENLLYKIGFDMNDHYADLFPVHSRT
                     YGGEIFSLPQVIERKVDSVVDVTEFIYVVEAQLDRQCMMKYDFFHCFPLIFFISTQKYY
                     FCVLFSTEIVQEMIEDIKKACQVMNEGG"
ORIGIN
        1 cacttcttcg taagattcct cggataagtt gtcggtggca cgcttgctga ggcagacatc
       61 gcattgcccg cagttgtgtt cgtttttctc tccgaagtag cggagaagca tccggctccg
      121 gcatatgttt tcggtggtga cgtattcttc cattgccttg atgcgtgctt catagcgggc
      181 tttgcgctct tcgtagacgc tgggggggat atgcaggaaa cgtaattcca gtcgttcgcg
      241 cgtatatata atataaggtg tctttttgcg gggaatgtag tccacgatgc ggcgtttggt
      301 taacgtcacc aatatattat agatttgctg gcgtgtcagt ccggtgcgga cggcaagaga
      361 ctcttcgctg atgtaggcat aatcggtgaa aactcctgtg tatgagcgaa gaatactttg
      421 tatcaaagct tccgcctcct ttcccatctc ccgcaacttg tatagttcgt cccgacggat
      481 ggtaaagaga atccgtgatg aattatcctg ttcgtccgtg tattccagat agcctgcctg
      541 agtcagtatt ttcaaggcac tgtctaccgg caccggaaag tatttgaact tccggcagaa
      601 ctcttccaga ttgaattcac ggatacattg aaaaccgtcg cccatcgcca tttggtaata
      661 gtactggaga tgttcgtaga cattcagaat gtactctttg tcggggaagg tgtcgaccac
      721 tcgtttatgg agtgttgtct tgtccgattt ggagtacagg atgacggcat aggctttctc
      781 tccgtctctt ccggcacgtc cggcttcctg aaagtaggct tcgggagagt caggcaggtc
      841 gagatgcagc acgatgcgga catccggctt gtcgataccc ataccgaagg cattggttgc
      901 caccatgacg cggacttctc cgctttgcca gcgtttctgc cggaggtctt tgacggcgtt
      961 atccagtccg gcatgataga agtcggcggt tataccttcg ttcatcagca gttcagtgat
     1021 ttctttggta cggcgtctgt tgcggacata gatgatggca ctgcccgata ttcgttgcag
     1081 gatatacagg agttctttcg ttttgttgtc ggttttgcgc acgatatatg ccagattctt
     1141 ccgttcaaag ctcattcgga agacatttcc ttcccggaat ttcagacggg cctgaatatc
     1201 tgttacgact tccggagtgg ccgtagccgt cagtgccagt accggaactt ccggcaatag
     1261 ttcccgtatc tctgcaattt tcagatatgc cgggcggaag tcgtatcccc attgtgagat
     1321 acagtggctt tcgtctaccg taatcatgga gactttcatc gaacgcaact tggtgcggaa
     1381 tatttccgta tccagccgtt ccggagaaat ataaaggaat ttgtaattgc cgaagatgca
     1441 gttttcgagt gcggtaagta tttcctgccg cgtcatgccc gaatagatgg caagagcttt
     1501 gatttcccgc ttccgcagat tctgcacctg atctttcatc agggcgataa gcggggtgat
     1561 gacgatacaa atgccctctt gggcgagagc gggcacttga aatgtaatag acttaccgcc
     1621 tccggtaggc atcagtccca gtgtgtcttt gccttcgccg atactggtga tgatctcctc
     1681 ctgcaagtcg cggaaggagt catatcccca atattgtttt aatatctcct gatacttatt
     1741 caatcggctt tatatcctcg atttgaagtt ggacttcgcc acgcttgtgc gtgttctcct
     1801 cgatcgtata gcagatgtcg aatgaacgct tcgtcttgat atagcgcaca tgagaactct
     1861 gtccgaatgc gatgccgttc atgacgttat tcgacttgtt gtcaaccagt tccagcttga
     1921 tatgttcctg atcgcgtccc actactttgc tggttccgta gtcatagacg tgatgcgtac
     1981 agaagatcgg tttgatattg tccggaccga aaggattgaa tttcttcagg tcattgaaga
     2041 atttcgatgt gatgtctctg aagtcgatct ccgcatctat attgatgacg gcgctggttt
     2101 gttccggcag aatatgttgt gacacatatt cttcaaatcg tcgggtaaag gcttccacat
     2161 tctccacttt catggataac cccgctgcat aggtatgtcc gccgaagttc tccaacaggt
     2221 cgcggcaatg ttcaatcgct ttgtacacat caaatccgga gacggaacgt gcggaaccgg
     2281 tggccatatc atccgtccgt gtgagtacta ctgccgggcg gtagtaaact tctgtcagac
     2341 gggatgctac gatgccgatg acacctttgt gccattcctc attataaagc acgatggaac
     2401 ggcgttcgga tagcccttcc agattggcca caatattgtt agcttcttct gtcatgctct
     2461 tgtcgaggtc tttccgggtt tcgttgtact gattgatctg tcccgctttc tccagtgcgg
     2521 cagaaaagtc cttctctgtg aggaggtcca ccgcttcctt accgttctgg atgcgtcccg
     2581 atgcgttgat acgtggtccg attttgaaca cgatatcgct gacggtgatc tccttttcgg
     2641 agagtccgca tacatcgatg atggctttca tgccgacgct ggggttgctg ttcagttgct
     2701 tcagaccgtg ataggcgaga atacggtttt cgcccatgat cgggacgatg tccgacgcaa
     2761 tgctcaccgc tacgaggtcg agcaatggaa tcagatgatg aaattcaata ccattgttga
     2821 tagcaaatgc ctgcataaac ttaaaaccga ctccgcaacc ggaaaggtgg gtgtatggat
     2881 aagtgttgtc caggcgtttg gcattcagga ttgcgacggc aggggggagg atatcgtccg
     2941 gcacatgatg gtcgcagatg ataaagtcga ttcccttttc tttcgcatac gttatttcct
     3001 ccactgcttt gattccgcag tcgagtacga tgatcaatcc tacgccggtc tctgaggcat
     3061 agtcaactcc ttttttagaa atgccatacc cttcgttgta gcggtcgggt atgtaatagt
     3121 caatgttcga atagaactgt tgaataaact tgtagaccag tgctacggca gtagtaccgt
     3181 ctacatcata atctccataa atcagaatac gctctttctt tcccatcgcc ttgttcagac
     3241 gttctactgc aatgtccatg tccttcatca ggaacggatc gtgcaggtcg ggcaattgcg
     3301 ggcggaaaaa cttcttgggt tgataattcc atttgtgatt cattttatat attgtttttt
     3361 ctttttctgt tctcaggggt cagaaaggcg ctactttcca acaaggggta aaagtacgaa
     3421 aaaaagcgga agggtatagt agatatgacg aaaatatttc aaaacctgtg gaattagctc
     3481 cttacgggct tggtattcaa atggagcaaa tgcatacaga tttgaatcaa ccgctgattc
     3541 gtattaatag ctaataaagc gaaaataaaa attaagtccg aagattattc tcctcataac
     3601 atcataaggt attcagttat atgacacaaa aagagaaagg tagtattgta gcaataattc
     3661 atcgatttac ctagaaaata aagaatcttt caaaatcagc acccacatct atacgaaaga
     3721 ctttgactaa ttatgcggta acagccaatc atttattaat aaattctttc atcgtttatt
     3781 ataaacgtcc tccaagttta ttataaactc taatttcgtt attcctgcaa taaacatcca
     3841 ttttaagcaa cgaaaagggc tgcaattccc ataaggaatc gcagccctta gcttgtatca
     3901 gactatccaa caagcattac ccggagtggg aatgcctgta atctgttatt atataatact
     3961 tattattgct catttttcgt ctatattatc aatgttatcg aatttacttc cggttttcac
     4021 ttacaaagat acaacattaa aagcggtttg tcaagtcctc catgcttctt tcatacatct
     4081 gattacaaat cacatataaa tgaattaatt tatatccgaa tatattagtt atatgacggg
     4141 agaagtatat ctttgtgtga ttagttgcta cacgaaatat gaatccaaaa cttacagact
     4201 gtttatgaga agaaatcttg ttggtatcat tgttctaatc ttgttgtccg ttagggtcgt
     4261 aaatgcacag actgttgctg actctatagc aatagtgaca gctccttggg aagtggtgac
     4321 cgtagaaaat ggaattgtac ataagcgggc ttccatccct tttctttatc aaggcactca
     4381 gtccattaat atattggaga taaatccgaa gactggcaaa aagatcggca ttgcctttac
     4441 tggacaattg gagaaaataa gccggattgc ccggaaacat caggccatcg gagccatcaa
     4501 cggctcctat tttgatatga cgaaaggaaa ctccgtctgt tttctgaagg tgggaagtca
     4561 ggttgtggac actacttctt tggatgaatt gaagttgcgg gtgacaggag cagtttatga
     4621 gaagaaagga aaagtgaagc tcattccttg ggacaggcag atcgagaaga actacaagaa
     4681 aaataaaggt tctgtgttag cttctggccc gttgatgctg aaagacgggg aatactatga
     4741 ctggagtcag tgcaatgcca attttataga aaccaaacat ccgcgtagtg ctatttgtct
     4801 gactgaagaa ggaaagattc tgtttgttac tgtcgatggg cgatctccgg aaaatgctgt
     4861 cggaatcaac attccggaac tggcacatct gcttcatgta ttgggtggaa aagatgcgct
     4921 gaatctggat ggaggaggtt ctaccgcctt atggctgtcc ggtgcaccgg aagagggaat
     4981 tgtgaacttt ccctgtgata acagaaacta tgatcatcaa ggagagcgta aagtggcaaa
     5041 cttcctttat gttcatgatt aaaataaaag tggctgtctc taaagtatag gtaagcttat
     5101 catctgatca ttcaaagcat aatgacaact gctttaagtt tagagacagc ctcttctgtc
     5161 tatttaaaat tcgaatccga tttttattcc tatgccatgc aggtcataag agctgtccca
     5221 ataataatcg ggaatatcat attcctgcaa gttgtattct agttttaagt tcagagccat
     5281 cttatttctt agagcaaagc gtacacctgc tcctaaagta gaataaagcc cctctatatc
     5341 tccggccgag tatcccgttc tgagttccat aaaaggggtt attggtctgt ttatgaaatt
     5401 agccctgaaa ttaataaaaa agggaactgt ggtaagactt gcatccgtaa agtggctgac
     5461 agcaactcct ccccccagga agaagtaatt attgaattga tacccgtgtg aagtggacaa
     5521 ttcaatcttg cttgcgtggt gcccgcttac gtcgactaca tatccgaaat ccacaaagcc
     5581 tttgtaacct ttcaatgtac tttgggttgg attatagtat tttttatata gtcttccgtt
     5641 ctcaatcctg agcacttcat ccattcggca gatgataagg ctgccatcat aggtcttgat
     5701 ctttatagaa acatcgggta tttgttctac gataagtcct ctgataacac tgccgttttt
     5761 cagatatact acttctgaat agttttgggc atcgcagtaa atgctgacgc ttactaacag
     5821 tatgaatagt agcagaatct ttttcataat ctttgtacta tccccgtttt acaggtgctt
     5881 tattgcattg tggatggagc ctgcccagta attccgcagt ccgaagcctc cggcttttcc
     5941 atcggtgctc cactcttcta tgatttcttt ggtatccgtg tcgaagaata ccacctgata
     6001 ggttcctctg ctggccgctt tattcagaaa ctcggcgata aataccatgc cgacgcccgc
     6061 ttctttgggt atgggaagtg cctgaatagc agcgttcact tgctccttag tcagagtgta
     6121 ctgtgtccgg cttgtgaaca attcatccgg attgatggct tcatttactt tgtttaccgc
     6181 ttccagcgag atttcgctta cctctttttt cagttgcttt cctacatcgt acttcttggc
     6241 ttccgcaata aaaagttcgt tgattcttct gaaagcgagt ttgaactcat agggggactc
     6301 tttggcaccg aatacctttg cctgagagta atccacacca taaaatttga tagactgaat
     6361 gtctttcgtt gcactgctgc cttgtccgaa actgaacagg ctgatgctca agaataagaa
     6421 tagaataagt tttttcatat acgttcatgt taaagtgatt aatatattgt gttgtcttct
     6481 tttagaattc gaagccgact ttcacgccaa tggtattcaa tgtctcatat tcgtcggtat
     6541 agccaaacca gtgggcaatg atcagttcat cgtgtccctg actggcaaat tcgactttga
     6601 gattgagtgc cattttagct ttcagcgtga tacgcagccc tgctgccaaa gaaacataga
     6661 ctccggtgat atctccggcg gtgtatccga gtctgacatt ggaaaatgga gtaagtttct
     6721 tattgagaaa gttggcacgg aagtctgcga atatcggtac agctgtacac tctgcatcat
     6781 tgtatctgtc caatgccaca ccgcctccga tatagaaatg attgttgaat tggaagccgt
     6841 gggaggtcga caactctaac ttattagcat taatcgtgtt tgagtttctg atgtcccaga
     6901 ggtatcctgc atcaaagaac cccttgtaac ctttcaaggc ggggcgttgc cgattcttga
     6961 aaactgggag gttctcttct ttagtgattt tctctacttc gtccatcgaa cagatgaaga
     7021 tatctccatc cgttgttctt atccgtagcg agtcattgga ggtttgctgg ataaagcttc
     7081 cccgaatgat gcttccgttt ttcagataca ctacttcggt ataggtctgt gccgtaccgt
     7141 aggtgctaac ccctatcagt aaaatgagaa ataacagtag ctttttcata tacgtcggta
     7201 ctaaagttat gaatagtttg tctaatcagc actcaaaagt agaaaaaaat tatcgtaaat
     7261 caatgaactt gatacttttt ctgctcatcg gtggcatttg tatcttggca atgtactctg
     7321 ccgactcgaa attgatggtc ggtgccactc ttactttgga acggaataga tccttgattt
     7381 ctttggcaaa gctctcgctg cggttctcgc ttcctatacg aatcagaatt tcatccgtac
     7441 ccagttcgtt ggtgtatact tctacaatgt agttcttcac ggatgggata ttgtcgagaa
     7501 tatcgaatag tgcgggggga tataaggtcg tgcctttgta cttgatcatc tgtcctttcc
     7561 ggccgaggat agagcttagt cggatggtgt ttcgtccgca ggcgcaaggt tcggtgtggt
     7621 ggtaacagat gtcgcctgtc ttgaagcgta gcaggggcat acctttcact cccagtgtgg
     7681 tgatggtcac ttcgcctgct tcaccttcgg ctacggggcg gttgtcgtcg tcaaggaatt
     7741 caacgatgat gagctccggt tgcaggtgtc cgccgtggaa ttcattacac tcggtgaaag
     7801 aagattgcat ttcggtggag gcgtaggtag aatacagttg cagggcaggc catttatcat
     7861 gtatcttttg tccgagggta ttcagctgaa agtcctgatt gcgcagggct tcaccgatac
     7921 agatgcactt ctgcatggag cattcattgt ggtcaatatg gtttttctcg gcaaactcta
     7981 tcagtttgat gaggaaagaa gggactacca ttccccaagt gggatgtatc cggcggatgg
     8041 tatcccattg aagttcgggg atgccgttgc ctacacgaat cactcccatg cccagttcgc
     8101 gggcgcccat gtagtaggcg agccctgcca tgaagcggcg gtcgatggta gtcatcagtt
     8161 gcaggacatc ctgtttggta catccggtgg tggtaaaaga caagtattcg ttgtaagaca
     8221 gccggtccag atcttcggaa gtcagaacga acgttaccgg atcgcccagc gtaccggaag
     8281 tggtcacgta atcgatgatc tcttctctgt ctacgcagat aaagtcatcg ttatgaagtt
     8341 gcaggtctgt cttggtggtg acagggattt gttgcaggtc ttctatcttt ttgatttgat
     8401 tgatatcaat atggtgctct tcgaacatct gttgataaaa cttggaattt gcttgtagat
     8461 aggctaatgc tttagccagt tgttcttctt ggtagcactt gatttcttcc ggtgagcgga
     8521 actgaatttc gggattcttt tccatcttag gattgttttt gaattttctg ttgaatacgt
     8581 tctttctctt gcagctttgg aatcggtctg ttcaatgctt ttttccaata gccaacggct
     8641 tgctgaggct gacggatcgc ttcgtaataa tctcccaaca cttcataaac aaagtagagg
     8701 gaaggattgg aagcttcgta tctttttaat acactgtctt ctactttttc ttttctcctg
     8761 atctttttca gtaatagcgg agtcagcttt ttgtaggtaa ggagctgctt gaactccggc
     8821 tgttccatga atgtatctgc cggaatcgtt tgttccggct cggatatttc gcgtaggaag
     8881 tcgatactgt cactgaatat cttattaagg tcgtatgcta cgtactttcc acactgccag
     8941 ggtgaggtgg atacccacat tattcgccgt tcgggctgga agataacgga atgatgagcg
     9001 ataaattgat tgatcgccat ttcattcgcc agtccgaggt ctgtattttg cagacctttg
     9061 tgattacgta ggatagaggc agctttagtt acatctatcg ggagtttttc attgattaat
     9121 tctttcagac gggcaaaacg gtaagggctg tcggaagtat ggatgttttc catgtttcgt
     9181 tcatctttgc tgaatgcttc cgattgataa tgattggtgc agataatccg gtctttttct
     9241 tctccggcga aaagtacggt cttctccggt gatttctcta taatggcggc cttaccgtct
     9301 ttagcggaac ctatgagtat ggactcggaa acgaatgtct gccgcttttg ggcaatcgcg
     9361 taggcttctt cgatagtcga cgcatattgt aagatctctc tggtcagaat ggagatcgga
     9421 gtagcggaac ctgtcggtac ggccgacttg gcggcattga tcgtaaccgt cagaccggtt
     9481 tcgttcatgc cggacaatac acctatcatg ccgggccatc ccacggaagc gaacttgtag
     9541 ccttgctccg gttcataaaa agaaaccagt ttgttgtgtg cgaaggcatc gcctacatag
     9601 aagtcgaagt tgcgtccgat cagtagagaa gagtctgcgc tttgtgtccc ccacgtggcg
     9661 aatgaactgc accctaccaa catataatcc tgcatggcgt gtcccagatc gtgtgccgaa
     9721 tggtagttca actggcgttc gtaaggagtg ccgataaagt catactcgtg tgtgcacgaa
     9781 agcgagattc catagatttc atcccgaaat tcctccgcaa cgtttttccc cagttcccgg
     9841 ttgaacagta cgatgaagaa ccggagaaac ttaaggtaac tttccgaagg aatgatttcg
     9901 cgtatctggt ctacaaagac tttctcctga tagtaaagca ggtcgggcga tagtttgccg
     9961 atcgcttctc ctctttgaaa ggcattccct tttatcttca gttcccataa accgctttgg
    10021 ctgtggcgca gatagttgtc tccatattgc cggaggctgt ccgtacggag cactttttcc
    10081 gcagaggctg tcggagtata tgccggagtt agcatatctg cggagaagta gagataacag
    10141 actcctccca ttagtacgac aataagcaat aaaaggatgc ctgttgcgta tttgattgtt
    10201 gtcttgatcc ctttacgcat ttccgacttt tttagctaag tattcttgtc ccacaaattc
    10261 ggcacaggta agcattgccg ttaacgtgac tcccaatgcg ccgtgtacat tcagattctg
    10321 accggtgagg aagagattgc ccaatcggct tcgtgtagat acaaagccga tttgcggaca
    10381 tttgtaatct ttgataatgc cgtaggcaga accctcttcc gtacctgtat agtcacggta
    10441 gctcaatggg gtagtggtat gtatctcttc tatacaatcg gagaaatcaa tgccatgctc
    10501 ctgaataaag cggagtatct gctgtgcttt ttctctcttg aatttccggt agctttctcc
    10561 ccgccgttcg ggagccgtat ctttccattc ggacagttca ttcatataca tcggggtcag
    10621 gatggagaca atgccggcat attggctgtc ttcggaagag gcttgcatcg aaatcatgca
    10681 gttggtggtc tgtcccggat attgctgttt gtcataccat acctcattgt ccccgtgcag
    10741 atataaattg cgattctgat acggaaggct tttctttttc atcaccagat aaagtgtgaa
    10801 gataccatac gtgttttcga gcgaactgat ccgggaaata taggcattct tgatgctgcg
    10861 gcttttatcc agtatctcca gcattcgttt gggatgtatg ccggagatga cagattcgct
    10921 ttccagccgt tcttctccgt tgataatcac tccctgtact ttctcgtttt caacaatgat
    10981 gcgggttacc tcactgttgt taagcactgt acctccgttt ttctggataa cattgattag
    11041 ttcgaggctg acttgcatac ttccgtcaac aaagcgatag gctccttcga tataggaatg
    11101 attgatcatt gcgtgctggt agaaggtgga aacatctttc agacctccat aaagtagtgc
    11161 ggaacctgcc agtacatttt gtaaagtcgg atcggggatt atatctgcga tcagcccggc
    11221 tgccgaagtg cagaaatact tcattccttc cagagcgatt gtgccttgtt tcagatgatc
    11281 tacactgatc agattgccga cagcctgcag ttctgcggca tatcgtttca gatgttcctt
    11341 ttcgtgaggg aaagactgac agagagtttc gataaactgc gggtatccca tcgcatagtc
    11401 atacgatttg cctttatagt agatggtatc gaaagcggta tcatccagcc gtcttacttt
    11461 cagcttgtcc atgatgccga aataacggaa atactggttc atcacttgtc cttcatccag
    11521 actgccgacg tagtgaatgc ctgtatcaaa cagattttct ttccgttggt acgtctggaa
    11581 gcatccgccg aattgtgcat tcttttctac cacgcatacg ttgaatcctt ctttgctgag
    11641 aattgcaccg cattccagtc cgccaaggcc acttccgatg atgataatat catatttgct
    11701 catgcgagtc cggttttctg aatatataaa tagtattcga tgtgtatttg tcattgggga
    11761 tgatctcgat gttcattcca aatgtcgccg ccatttcccg aagttgtgct tctgtggtga
    11821 agcagagttt ttcggtagtc cggttaaagt tgaagatacg tgtagacaat aactccgtca
    11881 accgggtcaa ccggtgcttg gaagtgttag ccgagttgcc gtcacgtata attatcattc
    11941 cttgcggacg cagcagagct gcacatttca atagcagtgt acgctgatgt tcataactca
    12001 tgtaatgcag catatcgttc agaatgaaca catcactttc cggcaacggg tattgcagtg
    12061 cattgccgta ttcgaaccga agacgttcat tgcgcagcca tccgtgttgg gctacggcta
    12121 tcttgtcttc atcgtaatcg attcccagaa tttcccgctc ttccgaaagt aaagacaagg
    12181 tgtagcatag cggtccgaat ccgcaaccga tatccgttat ctgtccttta acgggaataa
    12241 tctgattgaa cagccgataa ttcttctcca tctttacctt gatgcgaaca taccattctt
    12301 ctacaggccc cttgtagata tagttctgta taagtgcttc gtagaaagca ggattgtccg
    12361 tcgtattctt ttctctgcag atgcgcgcat actcttgtct catgtaggcc gatatgcgtt
    12421 tggtacgctc ctggtaagtt actccgaaag acagatcatc aacggggata cggggaagta
    12481 tttccgtata gataattcct ttgcggatat tgaagggctg tgctttggcg ataatcctgt
    12541 tgttgccgta tagtaagatc ggaaggatat ccagctgcaa cgtttctgcc agatagaatg
    12601 ctcctttgtg gaagcgtttc atctttccgt tgtaggtacg tgtgccttcg gggaagatag
    12661 cgatggagta tccctcctgt actttctttc gcattcgttc cacgtactgc tcgtatcctt
    12721 cgcctatgta atagaagtcg gcataccgga tgatggctcc gaagaaaggg gagtgccata
    12781 cccagtggtt ggtcaccata acgattttgg acgaaaggga cagcaacacc aggatatcga
    12841 taaacgactg atgattggca atgatgattg ccggacggtc gaatctttcg ttggtcttat
    12901 tgatgtgttc tttcttgacg gaggtagcta ccagcaggat tcccttgcag gtaatctgta
    12961 tcagtttgca aaccagatgc tgcttgctgc tcttgcgcac aggtatcgga taaagcacta
    13021 tgatcagcaa tctgagcaga atacatccga aaaagaaaag caggaaaagt atcaccgtac
    13081 gcatcaaacc gataacggta tacggcggta atcctttgga agcagggcct gaaatgaaga
    13141 aacggaaaat cagaggctgg atcgtatagg caaccagtac gaccgccatc attccaagga
    13201 tcgaaatcag cgaaatagat tgcaaggccg gatgtctggc aaatacaagc gctcccattc
    13261 cgactactgt ggtgaaagcg gagaagaaga tggctgtctt gtgtgagttc agtactttct
    13321 tgccggtgcg gtatttgttc tgcagtccgt ccatgatgaa gatactgaag tcatcgccga
    13381 tgccgaatat gaaagtggaa agaatgatat tgataatatt gaactcaatc cccagaatcc
    13441 ccattaaccc taaaatgatc acccagctga ccagcatcgg gaggaaactc atcaatgtaa
    13501 gttcgatacg tccgtaggag aaccataacg caaagaatat caggaaagaa gagatataca
    13561 ggatgagata aaagtcattg ttaacggcag atacccattt attggtgaag taagaacggt
    13621 cgaagatcac gacatctttc tctttgctga actgctcgta cactgcttct ttagccgttt
    13681 cattgacacg tacctgactg ataagcattg taatggaatc ggccgacgtc tgccattcgt
    13741 ttagcaattt accggataag tcctccgatt gtgcattata gacatactca tgaaaggagc
    13801 tatccagcca ttgacggaaa gaatcgaagc ttccgggacg gaaacggtag cccgctgcgg
    13861 cagtttccag gtcctcataa acctgttttt tcctatcatt cgtccagtag ctctgccact
    13921 tctccagacg tttctgctgc tcttgcggag aaatcaggaa ctgggaggcg gaagcatagt
    13981 ctttaatcag tccctgttct ttcagtgcag ctagtttccg gttggtttcc gcatatgttt
    14041 cagtagccct gttcatgtct ttccccacac tgacaaaaag gactgtcttt tcgtgattgt
    14101 caaagagctg catcagcttc tctcccgatt gtttaagatg cggaggctcg aagttgaggc
    14161 tcatcatgtc attattgaaa cctacctttt gcgaggtaaa cagacagatg acagtgatca
    14221 caagaatgct tcctaccagc catttgttct tctcaaaagg ataagcgttt attttctcaa
    14281 taaggcgcag cactcgtcct tgttttacat ctgcctgtcc tttcagaaaa tgcggcaggt
    14341 agatcagaca gaaaagagtc gtgcctatca atgccagaga agcgaataac ccgaagtctc
    14401 gcaacagatc ggaactggta aataccaatc cgaggaaggc gccgattgtt gtgaagctgc
    14461 cgactgtcag cggatacgct atctctttga ttaactgctg aacggtggat acgtgattct
    14521 gatgcgccag catatggatg gagtaactga gcgcaatgcc catgactgcc gatcctgccc
    14581 ctacggcaat agcggagata cttcctttaa taaaaaagat aagaaacagg gcaaacaatc
    14641 ctccgaacag tataggcgtg ataatcaaag gaatcgatct cttccgtttg aataccagcg
    14701 agatgaatac gataatgatg acaagggcga tggaagaggt cagaatcgta tcctgtttaa
    14761 tctggcgggc attgtaaact cctaccgagg gacctccgaa atattccgca cgaagggtcg
    14821 ggtgctgttt ctgtacttgt tgaagttctt cttccagtat cctgaccagt tcatcatttt
    14881 ttccggtgct gccggtactg aatacgggag taataaacat cagcagggta gaaccgtctt
    14941 gtgagaagat atgctcttca ttgatctcgt agttggcttc cagctgaaaa tcctgcaaat
    15001 gctttaaagc ctcgttgccg agtccgagag gatctctgag gatataactc cttaatgcga
    15061 ttccggcagg agaaagcaga cgggtgtaat tctgctgcat gattgcctga ataccttctt
    15121 tggtcagcag agaatcaagc ctttggtaat cggcatcaga gaggaaaagt ggcaggtgat
    15181 cgtagacaaa gtccgtagcc ccgccgataa ggctttggtc tacctgtgcg aagatttctt
    15241 taatcagctt atctccggct ttgtcggtca gcgtctgctg cagttggtcg gcagcttcta
    15301 tcagagagtc cggttctacg atgctgtcag tgtctgctgc agacagcatg atgatgatct
    15361 tatccttgat tttgaggtta tcaaatacct tgattgcatt ttgcgagtct ttggtatcgg
    15421 ggaaaaactg ggttacgttc tcttcgaacc ttacctgcag ggcaaagaat cccatgagca
    15481 gtacacagca gatgagtgac aaatagaaca aaatcttgtg tctctcaaaa tagtcatata
    15541 gtccgataaa gaattgtgtc atatcttttt tcttctacaa gcggtaagca gcacgagggc
    15601 gacgattccc gccactacgc tgcaaacgac tgcaaagata acacttccta tcaaatattg
    15661 ctctatgacc gattttacat tttcaaagga tagttcgttt aattgcaggt tgatgggttt
    15721 tcccagcacc ttgcatccgg ttacatagct tccgtatagc agaaacggaa tcatcggagg
    15781 gatactgata ttggctgcaa cgatagcgat gactttattg agtctgagca gatgcgccag
    15841 aaataaggtg atcagcatct ggtatcccca aaccggtacg atacccataa atacgccaag
    15901 catgatggta ctggtgattc tcagattgga ctccggtgaa tgagtgacat gatcggagaa
    15961 gaacttcttg cagttctgcc aggtcagctt gcggaaaaag ttacggggga tgatccacag
    16021 gaacgtgata agtaccagta ttgtattcag aatactgata cgggtaaaat cctgaaaggg
    16081 acgaaaatgg gatactcttt cttcctgagg gggataatag acgtgtaccg gaatgttttt
    16141 aacggcaatg cctccccatg ctgcaaagac gagggcttcc agttcaaatt catatttagc
    16201 ggtatagtac catctgtcta cattcatccg ttgcagcggg tagagccggt agccggactg
    16261 tgtatcttcc agtttgatcc ttgtctccaa ggtaaaccag aaattggaga acttgttggc
    16321 aaatgtattc tttcccggca tattgtccga agccagatta cgggcaccta ccaacagggt
    16381 atcttgttct ttttctatgg cctcgataaa ttcggggatg tccgaagcaa aatgttgccc
    16441 gtccgaatca atggtaatgg catagcggta gccttgccct tttgcgtgac aaagtccgtg
    16501 tttcagcgcg gtccctttcc ccttattgac ggggtgggta atgacttgta tctctgtgta
    16561 acggttgagt ataccggctg tctcatccgt cgaaccgtca ttgacgacga ggatatccgg
    16621 agcataaaac tgtacgctct ctataaccgc ggcaagggtc tttccgttat tgtagctcgg
    16681 gatgataacg atgattccca gttgctttag tgtttcgtgc caataggctg tacatctttg
    16741 ttccttcata actggggggt aagtacggct tttagtttga taaacggctc atcctttgcg
    16801 atgccttctg cctgtaactg gaggttgtgg tcctctgtct ctttcacgct ccatgtcaat
    16861 gatatccggg gagtatctgt ggggttgata gccgaaagaa acttgcagga ggatatttgc
    16921 gtatattgca tcttttggtg gcgtatgttt tctacgctct ccttgatcag ttgcagcaga
    16981 cagacgccgg gtactaccgg atgcgcaggg aaatgtccct ggtagatggc atgatcggga
    17041 ttcaattcga gaagaaccgt tccggatgtt tcgtccggtt gttctgacga caatatagta
    17101 tagaaattgt caagtagcat atcagttgtc tttaggcagt ttatcgagtt ggatcgtcaa
    17161 tcgtatccac gggtgtctta ttcttacttg ttccggatct ccctgagttt ctccggtgat
    17221 ggatacgatc gacttcccga atccttttcc actagttctt ttttcaatgg caccgtcttt
    17281 ggaggtccgt acccgaatcc ctttgctgct aaggaataaa tgcttgaaat ccatttcgag
    17341 caacttcagc actttctctt tttgcatggg agcgacgcag ctgttgacaa ggaaattctc
    17401 tccacgcagg gaaaaatcaa aaaggcttaa accgaaataa gtcgatgcca atatccgtat
    17461 ttcattctcc ggcatacgcc gtactatcag cataccgctc aaatgatgtt tcatgaagtc
    17521 taactggatg ttgtactttt gcgaaccttt tcctgccgtt aattcgatgg caggaggcac
    17581 agtgccgctt tctccgctta tccgcgggga gcaggaagtc tgtagctgca ctatcaggaa
    17641 gaacagtacc gacaggctag cgaaccgcaa acttcgtctc atccttcagt gagttaaact
    17701 ttttatgata aaattcgtat tccgtatagt tagtagctgt ctcggacagg cggagtttgt
    17761 ataccgacat atctttcttg tccagccaga tttctatccc gttgatataa gcctgcaccg
    17821 ccttgttggt cggcttgatc ttgacgagat agtaatgcgc atcttcaaag tattctagct
    17881 ggtaactgga agacatcttg gacaggtcgc ctatcatgca ggccgtcaac atatcttgca
    17941 tctgattcat catcttgttg gaactcagat tcatgatgct cttctttccg tctgagacga
    18001 ttttgagttt gttgccattg atgacgatga gataatccat tggacggaaa tactccatac
    18061 agatcttgtt gctcttctga tagctgaatt tgcctttcga ggtcactttc tcatcgaaga
    18121 catccagata tttcacttgt gtgaagtcgc tttcgatgga ttgtacggtt tgtgcttcct
    18181 ttgccagccg gctctcaaat tcctgaagtt gcgtcatctt cttcatcgtc tgagaagaca
    18241 cggaagcgat ggataagaaa ctcagtagta aataggttga taaagttctc atacgttctt
    18301 gtattatgtc catagtttat ccagccggac aacggtatac tcctgttctt tcagtaaatc
    18361 cagtatttgc ttcaccaaca agtcgctgtc gggcatccgg tcgtgcagca agatcactga
    18421 tcccggcgtc agacgtttcc gtatccggcg aagtatttgt tccggtgcgt gttgttgggt
    18481 atccagtgtc cggatattcc atcctatgga ggtatatccc aattgccgga cagctttcgc
    18541 aatggtcgga ttggtcacac caaacggcgg acgaaacaaa gtaaccggct gcgaagttac
    18601 ttgttctagt tcagactggc aagtttgcaa gtcttttttc attttagaga gaggatagac
    18661 tggaaacagg gccgagtgcg tataagagtg gttaccgata agatggcctt ccgctatcat
    18721 ttgttgcagc agtttctcat ttccctttat ctgctttccg atacagaaaa agcaggtatt
    18781 cacctgatac gctttcagta cttccagcac tttgggagtc tgaacggaat cgggaccgtc
    18841 gtcaaaagtc agagatacga tcttttcagc ggtttgtttc tggcaaaacg accggagata
    18901 gattcccgcc ttgatgctgt aggaggcata gacaagggcg gatagtatca gtagcagaca
    18961 aagaacgaga caaccgatga tcatacgctt ttccggatta gcatcaaaga atgattgatg
    19021 gagtggtgat gattgtatat caataggtta acagtgtcat tgcaagaggc taattccttg
    19081 actgctttcc atactgcata agaggaggcg gtaggatatt ctccacattc gtctttaaag
    19141 ctgagggaaa ggctgttcgg gaaaagctcc gtttcgagct tcttgtagat ttcattttcc
    19201 cctttgatac taccgtcttg tagggagaat ctgttctcct ctgtaatgac tgtgtccgtt
    19261 ttatcagtcg gtccggtttt gccggtaatc agccagtgaa tatcttgagg ctctaagccg
    19321 tatcgttgca gaaaacggga gattctgctg ctgatttctt cggccgtttg ctttccggca
    19381 taagtttcta ctcctctgat ttctgccagc gaatgactgc cggcttcccg gctcagaaga
    19441 aaaaactgtg cgccttctcc ggcttgtgtc cctttgagca gtcccagacg ttgctggatg
    19501 atatagctgc tgtccgtgat ttcatccact gctccgacaa gtatgttttc actcccttct
    19561 tctatcttca tcatggcatc cagcagagcg ctttcaaaac tcaatccacg gtgaacgtag
    19621 gtcatgttat aggcgtgtat ctgacggagc aatgcgattt gtgcaccaat cgtgttgaag
    19681 gtggattgaa taaagggagt cgggttcagc atccgttctt cattgtctat cagtgtgttc
    19741 agaaactttt ccgtatcgct cagacagcct aagcctgttg ccgtaatgat cccttgcatc
    19801 ttttcgggag cgatgtcggc gatacattcc agtccgcagg ccacccccat ctttatgata
    19861 cggctcatgc gtctgcgaag ggttgtattc gtaatgatca ccttgtagtc gggttcgcaa
    19921 gccgataaat acggatgatt ctccggattt ccctgcggat gaacggaagc ggtatgctgg
    19981 atataaacag gttgcatagg tcagatactt aaaggttcgt tgacaacgga aaaaaggagc
    20041 gatgagtcgt tccctccgaa accgaaggag ttggacagta catgccggat gggtaatcct
    20101 tcacggaagg atgtttccgg cactaatccc gtttccgaca tgggttccgt aaaattcaga
    20161 ttcgggtaaa ccataccttt atatatagag agtacggaat agacagcctc aatgccttcg
    20221 gaagctccta acgtatgtcc gataaatgct tttaccgaac tgaaaggcgg gacagccttg
    20281 ccaaagattc tccgtagtgc ggtaccttcc gaagcatcat tgccgggggt accagtgcca
    20341 tgtacgttaa tataatcaat ttcttccgca gagacaccac tggaggcaat cgcctcgctc
    20401 atggaagaga atgcgccgtc tccttccgga gagctgcctg tctggtgaaa agcctcgttt
    20461 gtattggcaa atccgcttag ctcacagtag ggagttctct ggagtgactt ttccgattga
    20521 agtaccaggt atccggcccc ttcaccgaga ttcaatccgg cacgggaacg gtcgaaaggg
    20581 cggcagtgat ccttgtccaa aatcatcagc gaatggaatc cattcagagt gaaccggcag
    20641 agggcgtccg tgcctcccac tatggcagcg tccagctgac cgtgtctgat cattcgggct
    20701 cccagtatga cagcgtttgc tgctgacgaa caggcggtgc tgatggtcgt tacaaaatct
    20761 ctgatgccca gatatgaagc aatgagttcc gtgctggcac cgcaatcgtg agaaatcact
    20821 tcccgtagtt gtccccggga gggatcttgc ttgaaagcct cgtagaaatg ttcgctgaga
    20881 tccatgccac cgaccgacgt agcggatata aacccgatgc gcagcggttg ctgctgtggg
    20941 gtattccgtg tgccctgcat agggagtccg gcatcttcca gtgcctcttt ggccgccatc
    21001 attccgagca gtgccgtacg ggaaactgtt tgtagcggag acagcgataa caactgtttc
    21061 agtttctcat tgtcgcattt cacttcagat acgggcacat cgagtgctgt cgggaaaagg
    21121 gttactttcc cgatgccatg cctcttttgc ttcagagcct ctatattctc agaaactccg
    21181 atgccgatac ctgaaatgac tcccagtccg gtgacgtaaa tcttcatgga ttacttttta
    21241 cggttggcag tgatgtaatc ggccaaggta cgtaccgaat agaagatttc ttttccttta
    21301 cccggatttt cgattttgat gccgtattca cgttccagaa tcaggatgat ttcgagcgcg
    21361 tcgatcgaat cgaggccgag tccttcgtct ccgaacaggg gcgcttcgtc gtcgatatct
    21421 tccggagtga tttcttcgag gtttaactct tcgatcagtt tacctttcac ttcgtctctt
    21481 aattctcttt ccttttcgct tgtaaattcg ttcatgggtg ttggtatata agttgtttaa
    21541 attctgcgtg ataatgtccg tcaaatagtt cgcaccagcc gatgatacag gtttgcagct
    21601 tccctttggc cattacgata cgtgcgtaat cttccagcag tgcttcatcg taattctggc
    21661 tgacaaagaa cgtattctct ccctgaatct tgtggcggat acatatttcg cccagtacga
    21721 cattggggag cgtatagacg aatacggcag ggctggcaga cgcatctccg tctttgctga
    21781 tgatagcctg gtgtttgcag tctgtatcca gcgacgaaga ggtgttggca agtagaatcg
    21841 ctattttttc cggctgatag gctgtgtctt tcagcaggta cccggcagct acataaccca
    21901 gtttgcaaag atcgtccatt ttgtagaact tcatgttgtt ttcgcccagg cttttgtacg
    21961 cttcacggat aaacggtgca aattctgttt cctgtgaact gaagatggtt ttccctgcta
    22021 gtttaacggt tccccgcttg atggagacgg tctgacaggt agttatgggt tgtatgacgc
    22081 atgactgtcc ttgtttctga taagctggga gagagagaac aattgcggca ttgcatcctc
    22141 cgaaaccgga agccgtcttg atacaggatt tcatcgcaat tgattggtgg gcggcattga
    22201 ctatgacagg cataggcact ccgggagtct cgtatcctaa tgttccatac atgatgcctt
    22261 ccttcagctg ctcgatacaa agaatgcttt cgataatccc ggaagctcct aatgtatggc
    22321 caacgtacgg tttcagactg ttgaccggta ccgaagacag acctgccaga tggattgcct
    22381 tggattccat ctcatcgtta tagatcgtag cagtgccatg tgcattgata aaactgatat
    22441 cttcgggagt tactccggct tctttcattg cctgactgat agcgagagcc aggccgtcac
    22501 cggttcggga cggaccggag atatgattgg catcgttgct gacagcaccc cccgaaagca
    22561 gtatatcctt tgcactgcct gccgtactca gtaatacggc tccgcaggct tcgcccagat
    22621 tcaggccatc ccgctgttta tcatacggcc gacaccgttg cgcgctgaca gacctgaaag
    22681 acaggaagcc gctggtgata aagtgagaaa gaatatctcc ccctgccaca atcacttgtt
    22741 tgtaacgtcc tgtttctatc catcttttgg caacgattaa ggcagataca cctgatatgc
    22801 aggcattgga gatcacttcc acccgattgg ctgtccggaa gaaacttccg attcgctcag
    22861 ccattttccc aaggaagacg ggactgtcgc ccaacaagtc tatatttcct ttggttgtag
    22921 aaagtaacaa ggcacaatcc tgtttgcaga gatcggctcc cgactgggaa agtatctcct
    22981 gtatggtgag tatgaacagt tgctccaagc ggggataagc ctcaatttgt gcctgtcgtg
    23041 cccgcttttc cagttcggcg gagtcaatca gtcctgcctg tatcggggtg tcggatatcc
    23101 ggttgccctc agaatccggt cctgcttcct gcagatggac tccactccgg taagtacgga
    23161 tcgctttcag gttttcctct gtaccgaagc ctaacgagct gatcagcgta tgggctgtga
    23221 tgtatatatt caaaggatgt tccatttctt tttccactcc gtgtaaaaag gaggattaac
    23281 aagttcaagt tctttattca gattcagaaa cacctgtata gtgcttccgg tagctacaac
    23341 gctttggtct gtagcccggt agatcacata ttcgaaatgg attttggctg catcgcaggc
    23401 gatatagcgt gtttcgataa tcgcctcctc gccaaaggac agcgactgtt tgaactgaca
    23461 ggtcaaatca acgatgggaa ccatataacc ttccctgtaa atgctcatat agtccaaacc
    23521 gtattgcctg ccgaaagcct ctcttccgtc ttcaaaataa cgtacatact ctccatgcca
    23581 tacaatttgc atggagtcta tctcgctgaa ccgtactctg agtgtagtcc ggttggtcag
    23641 agctgcgctg tgctgatttg ttttccgttt cattctttct ttataaatat tttcatccgg
    23701 cattcagttg tcagttcttc atccgctttt acttgtgccg aaatcaaggt aatgtcaaag
    23761 acttcctgca caacggtgat ctccgtcaat agtttctgtc cgacatccgg caggctgtaa
    23821 atctttagtt tatccaccga accgataaat cccaatggga cctccttgcc ttgctgtgta
    23881 taaagaaatc cgatacgtgc ggcggccgat tgggcaatat gttcgatgag tcctgcttcc
    23941 tgtagctttc ctgcttcgca gaatatattg tcggcggtga cggtcagtcc cgaatacgaa
    24001 cggttttctt cgatgccgaa gaaacaatcc accatgacta tcggtggacg ctgcggaatc
    24061 agtccgagta ttccctctcc gtgtatggtt gcttccttgt tcatttcaat ctgcattgta
    24121 cgatgctgtg ccccatcccc aggtggtcat gtatttcttc tatctccaga cctgccgctt
    24181 cgatgcatcg tttcatgtca tccgaatgat acatcttgct gtttccattg gccatagccg
    24241 taaaataaag actgatttga gtcagacaat aggcggctgt atcgaacttc tgacggttcc
    24301 agaaggtttc catgatataa agacggccct ctttgttcat agaacgtgcc gcacgggtca
    24361 gaatgctggt tacctcctct tccgagaagc agtcgaggaa ctggctcatc cagatagcat
    24421 caaatccagt gggaaaagga acagccggat cgagcagatt ggcaccgtgt ccgtgaatac
    24481 gtgccgcttc gggcaattct ttggtctgtt ggcgcatcat ttccagttgt tgcggaaggt
    24541 ccatgatggt cacttctacc gtcgggctat aacttacgca tcgggttgcc catcgtccgg
    24601 tattacctcc tacgtccagt aaggttttgg gatggcgggc gaaaacgatt gacagtgctt
    24661 cgtcgaaaga gcaatccgag taatagtggt cgaagccaaa ccaactcttc tgtacctgag
    24721 tcggcagact ggacagtcct tcataaatag tactccattc accgaatact ttcagacctt
    24781 ccggacgccc ttcagtcagt gcttcttcga gatggaacat tcccagatag ttgacatcat
    24841 ggttgaaatc catattcacc cgtaccattt tgtcgttgag caggaaccag ccggctttgg
    24901 caagctggta gtgtccttca caaaggagga cggtaccgat tgttaacgat gcttccagca
    24961 gtacctgtac ggcataggag gacagtccgc aagccttgct gatttcttcc tgtgtcagtc
    25021 cttcgcgtcg gtcggcgagt aactggaaaa taccgaattt aagcatcagt cgtgacactt
    25081 ggaatacaat aggtccgaaa gctatttcct gtgccagccg ttgggcctct actgctgtca
    25141 tcggttcttt gtcatatcta ttctgttgca tctctatgtt tttatattga atctgtagct
    25201 tgctttgttg caggcttcca gaatgaataa taattaaacc attgctccgg ataacgtttc
    25261 aagatatgtt ccagagtcgc tgtatattgt tccagcaggg cggtttcggc cttattctct
    25321 ttgcttcgtg tcaccggttc cgccacaaag aagtggaaac gatacgtcct tcccggttcc
    25381 ctcatggcaa agtagaacac taccggaact ttcatgcgcg aagccagcag gaaaggaccg
    25441 gcaggaaaag gagcttcctc tcccagtaaa cagcctgtca gcagcttctc tttgttcagg
    25501 tagcggtcgc cttgaaagca gacatattct tttttgtcca gtgcttcggt aatgcggaac
    25561 acgtgcgtca gattatcttc gttgaccgga ataatcttat actccttgtc ctgcccgttt
    25621 ttctccagca tttctttgat tttgcgatgc tcggcgtcgt acatcacaat gttgatcttc
    25681 tttccgtaat catcgaagaa aggaacgccg atttcccagt ttcccacgtg ggcaccaatc
    25741 atgatcactc cttgttcgct gttcagtaat tgcagaaatt cgggatatct ttcgaattcg
    25801 aaccggtatt tctttacttt cccgttggcg atggctactt tatctatcaa aatttgtccc
    25861 aatcggtaat aattgcgaag cagcataccg aaagagcgca atcggctgta tttaaggata
    25921 tggcgggcat aaaaccacgt gcttttcgtc gctttcggtg cgaaaggaat gaagtagagg
    25981 actaccagac tcagaaagcc ataggcggca gtgatgccca gatacttaat cagataaatg
    26041 aagaataagt atccgaacgt tcctccccgg gttttgcctt tccacgtcga catatactta
    26101 ctttgcttct tgcatacggg tgatgacaag gtcgtagaag tcttggaagg tcttgatacc
    26161 tgcaaagtct tgtcccgtca cattaaatcc gaagttcttt tctaccaata ctaccatatc
    26221 aaccaaatcc aggctgtcca gttcgagcgt ctccatcagc ggggcatccg gttggatgac
    26281 ctcgatgtct acttcaaact cttctgccaa ggttattctt attttctcga taatttcttc
    26341 gtttgtcata tatctatagt tctattaatg gattattcat tgattttacg caggataagc
    26401 gtggagttgg ttcctccgaa tccgaatgaa ttggaaagga aggtatcaaa ttccatatct
    26461 acccgttgtg cagggatgtt caactgtgcc gaagcttcgt ccggttcttc gaagttgagg
    26521 ttaggagcga tgaagccgtt gttcatcatc aaggtggagt aaatcacttc actggcaccc
    26581 gccatccaca tttcgtgtcc ggtcatcgat ttggtcgaag tgacatacgg acggtgtcct
    26641 tcgaatactt cggcgatcgc tttggcttcg ttcaggtcgc ctaccggtgt cgaagtggcg
    26701 tgcgcattga tataagcaat ccggtcgagg gcgattctcg catcctttat agccatctga
    26761 agcgaacgtt tcggaccatc tacgttcggt acggagatgt ggtcgccatt ggatgaaaaa
    26821 ccatagccga tgacctccgc caggatgggt gcacctcttt ttacggccga ttcatagctt
    26881 tcgagtacca gactggcggc tcctccactg gggatgaggc cgtcgcgtcg tttgtcgaaa
    26941 ggttttgagg ctttctttgg ctccgcttcc tgcgtagaga atgcgctcaa tccgtcgaaa
    27001 ctgcctacgg catacggatt gacttcctgt gcaccaccgc ataagatgca atcctgtagt
    27061 cctgatttga taagcagata acccatgccg atagcgtgcg aaccgctggc gcaggcacct
    27121 gcgatagtga agttgacccc tctcagtttg aagatgacag acaggttcat ggtcaccgtc
    27181 gaattcattg actggaaaat ggaaccggaa cctaccagag ccgtgttctt cttttcacgg
    27241 atgatgtcta ccgcattgat gacgggagcg gcactgctgt cgttaccgta taagataccc
    27301 acttcgttgg cttcgagaaa agcctcgtcg atgccagcgt tgcggaaagc ctccagagtg
    27361 gagagataag catattcacc ctgctccggc aggcaaagac gtttgcggcg atccaacagc
    27421 tttttcagtt cgggacgttc cagtatgcct gtcagtgccg aaaaataacc gagttctttt
    27481 cgtaccggat cgatgccgat gcccgatttt ccgttatata gtgagtcttt tacttcatcc
    27541 agattcttgc cgatgcaaga ataaatcccc attcccgtga taaccactct tttcatttga
    27601 tgtctgttct atcttttgtt tttaggtata tagtcctccg ttgatggaaa tcacttctcc
    27661 cgtgatgtaa gaggaggcag gggaggccag gaagccgacc agttcggcca cttcttccgg
    27721 agtcccgaaa cgtcccgcgg gaatatgttt cttccattcg ttttcgtcga tcccttccgt
    27781 catgtctgtg cggataaatc ccggagcaac ggcattgaca gtcactttct ttttggctac
    27841 ctcctgtgcc agtgccttcg ttgcggctat tacgccacct ttggcagcgg aatagttggc
    27901 ttgtcctgcc attccctgta tgcccgacaa agacacgatg ttgataatac gtccgtatcg
    27961 cttgaccagc atatttttca gcaatggctg tgtcacgtag aagaaaccgt tcagactgat
    28021 atcgagcact ttgctccatt cttcgcctgt catccagagc atcagattat ctttgcggat
    28081 accggcattg ttcacaagca cttcgatata ctcgtcgggg tgccgggcat tccattctcc
    28141 caaagcatcg gcgatggcgg cagggtcagt tacgtcgaat ttcattaact cgccgtcact
    28201 ccctttttcc cgtaccagtt gcagtgtctt tcctgcttcc gtatcgttac tctgatagtt
    28261 gataagtatg aagtagccca tctccgccag cttgcagctg acggaacgac cgataccacg
    28321 gcttcctccg gttactaatg catatttcat attatttatt ttcttttttg agatagctta
    28381 tcattctttc tatctctttg tatttgggtg tatcctccgt gaatacaggg aagaaactgc
    28441 gtatttcctt atatacccga cggcttttgg gactcagctg ttcctgaatc ttcagatagt
    28501 cgatggcctg cacaatgccc ataaactgga tagccatcac ctgatacgaa ttctctatga
    28561 cttttttggc cagtaatgcc gagttcgttc ccatgctgac gatgtcttga ttgtcattgt
    28621 tgttggggat gctgtgtaca tacatcggat tcgataatgt ctgacattcg gcagtggtag
    28681 aggtggcggt gaattgcgaa gcctgcaaac cgtagttcag ccccagtact cccagattga
    28741 cgaatggggg cagaatactg ttaatacggt cgtggaacag atagttgatc tgcctttcgc
    28801 aaagcatggt cagcttggtg acggcgattt ttagtttgtc catctcgaag gagatgtaat
    28861 cgccgtgaaa gttaccgcca tgataaatat tctgcgtttc cggatctaca atcggattgt
    28921 cgcaggcgga gttgatctcg ttgatcaata ccttctctgc attttccagt tcgtcataaa
    28981 ccggtccgag cacttgcgga acgcagcgca gtgagtaata agcctgtact ttacgctcga
    29041 agattttttc cgtatgtatc tggttgtata attcgttttc tcttttgcgt acacattggc
    29101 tgcctgccac ccagtctctc atcatggcgg ctatttcctg ctgccctttg tgatgcttcg
    29161 cttcgttcag cgcctgcgac atgaggtcgt cataagaagc tgcgatttca ttcattatca
    29221 ctgaggctgc taccgaccag tgaagcaggt tgcgggcata tatcagatta acaataccga
    29281 tgcctgtcat taccgaagtc ccgttggtta cggacagtcc ctcgcggata cgcattgtaa
    29341 agggtttcag attattctcg cggagaacgt cggcagcatt gcgtaaccag ccttggtaga
    29401 acacttctcc ttcgcctatc aatgtcaggg cgatgtgtgc cagttgcacg aggtcaccgc
    29461 tggcacccac gcttccgtgt tcgggtatga acgggtaaat gccacgattg atgaattcgc
    29521 aaagaaggga taccagctcc atgtgtaccc ccgactttcc ttgcaggaag gtatacaggc
    29581 gtgcgatcat ggctgctttt acataaagtt cgggaagcgg ttcgccggca cctgtagagt
    29641 ggctccggat gatgttgtat tgaaggtcga tcagtgactg gtcttcgatt ctgtattgag
    29701 ccatcggacc gaatccggta ttgatgccgt agataatctt gtcgctggag aaagattgca
    29761 ggaaatggaa actttcctcc acctttcgga tacattcttc ggaaaggtct agtctttcat
    29821 tttcaaacaa tactttgtag agggtatcca gatttatact tttgtcagct gtcattttac
    29881 gctatagata tttcgtacct tatattatta aggtgcaaaa ataggcaatt tctattatat
    29941 agcggacatg attcagtata aaacttttct tatcgctcag gttttggctc tccgaagtca
    30001 ggcagcgatg aggaatggtc ctggcaccgg ggaaggctta tttctttcag tttttcttct
    30061 tgcgtacgtc cttcccttcg aatttgcaga ttgcctctat ccagtcttcg gttagcggca
    30121 tcgactcatg tttttccagg tcgaaagtta ccatgatcga tttgcagata catttcacct
    30181 ctagggtttc cgtgtcgatc acccgttgga tgagatgaaa gcttttggtt ccaatttcag
    30241 aaacggcggt ttgtacggca atatgatcgg atgcgaaaat ctgctttaca aaattggctt
    30301 cgatatgaac gaccactatg ccgatctttt cccagtccac tcccggacat acggaggcga
    30361 aatattcagt cttccccaag tcatagaaag aaaagtagac agtgttgttg acgtgaccga
    30421 atttatctac gtcgttgaag cgcaactgga taggcagtgc atgatgaaat acgatttctt
    30481 ccattgtttt cccttaatct tttttatttc gacgcaaaag tactactttt gcgtgttatt
    30541 ctcaacagaa atagttcaag aaatgataga agatattaaa aaagcctgtc aggtgatgaa
    30601 tgaaggaggt
//
