LOCUS       c00045_gnlPro..        13217 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKFEMOPI_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:50:28
            Original ID  :: gnl|Prokka|CKFEMOPI_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13217
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13217
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3217]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3217
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13217
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13217
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..967)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 7.7e-120,
                     bitscore: 390.3, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAIHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKR"
     CDS             complement(974..2311)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_2"
                     /sec_met_domain="Fer4_10 (E-value: 2.5e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.7e-16, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.1e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.2e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVTKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPIAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(2336..3217)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.5e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.1e-08, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.3e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.9e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4.7e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.2e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             complement(3224..3649)
                     /locus_tag="ctg45_4"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDITDVTAASYQVGERVMVIGETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNEL
                     YAALLSLAVLIPYYFVLWLNKTRMKQHFSFTIKPINN"
     CDS             complement(4008..4529)
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MSVIYKVVTRPSDPRVPNSPKKYYPHLITLGQSVNLKYIAQKMQG
                     YSSLSIGDIKSVIQNFVEKMKEQLLEGKSVNIEGLGVFMLTACSKGADAAKDVNAKSVD
                     SVRIFFQANKELRITKTATRADEKLDLISLDEYLKKLNASVTPNDPDDGENGGGGNEGG
                     GDEEAPDPTV"
     CDS             complement(4686..7124)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_6"
                     /sec_met_domain="CbiA (E-value: 2.3e-10, bitscore: 31.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEENQNVKEREIAEDQIDFRALFFKYIIHWPWFVGAVLLCFVGA
                     WFYLHWATPIYNISATVLIKDEKKGGGAGLSSELEDMGLSGLMTSSKNIDNELEVLRSK
                     TLVKEVVNQLGLYITYKDEDEFPAKGLYKTSPVQVSLTPQEAEKLTTPMIVEMTLQPEG
                     SMDVNVTIGEKGYQKHFEKLPAIFPTDEGTLAFFQAADSVTLQDGTKVPRIEKSVRHIT
                     ATINKPMRVARGYCNSLSIAPTSKTTSVAVISLKNSSLRRGQDFINQLLEMYNRNTNND
                     KNEIAQKTAEFIDERIGIISKELGSTEANLETFKRDAGITDLTSEAQIALAGNAEYEKK
                     SVENRTQISLVNDLSKYLRGNEYEVLPSNVGLQDAALIGAIERYNEMLMERKRLLRTST
                     ENNPTIVNLDTSIRAMKANVQATLEGTLQGLMITKESLDREASRYSRRISNAPGQERAY
                     VSIARQQEIKAGLYLMLLQKREENAIALAATANNAKIIDEAIADDIPISPKRSMIYLIA
                     LILGVGIPVGIIYLIELTKFKIEGRADVEKLTSVPVVGDIPLTDEKNDKNGSIAVFENK
                     NNLMSETFRNIRTNLQFMLDNDQKVILVTSTVSGEGKSFVSSNLAISLSLLGKKVVIVG
                     LDIRKPGLNKVFQLSNKERGITQYLSNPEMDLMELVQPSDVNKNLFILPGGTVPPNPTE
                     LLARNGLDRAIETLKKNFDYVILDTAPIGMVTDTLLIGRVADLSVYVCRADYTHKAEYT
                     LINELSFEKKLPNLCTVINGVDLKKRKYGYYYGYGKYGKHYGYGKRYGYGYGYGQDTKR
                     "
     CDS             complement(7136..7930)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_7"
                     /sec_met_domain="SLBB (E-value: 2.3e-09, bitscore: 27.8,
                     seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIKQLVYCVLSVFLLTACQSYKKVPYLQDAEVVLYSTQNEQLY
                     DAKIMPKDLLTIVVSCTSPELAAPFNLTVATQSNAALNYTTTQPVLQQYLVDNEGNINF
                     PVLGELHVGGLTKKATEQMIVEKLKPYITETPIVTVRMVNYKISVIGEVARPGTFTISN
                     EKVNILEALAMAGDMTVYGLRDDVKLIRENANGKQEIIPLDLNKAETILSPYYYLQQND
                     IIYVTPNKAKARNSDIGTSTSLWFSATSILVSIASLLFNILK"
     CDS             complement(8045..8698)
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MENELGNLSHKMIMQSLDWAYDKAVNGVKGLDSAEELAKDYLTQD
                     GSLLDQINALIRWQNAKAGTSGFVTGLGGFLTIPITLPVNITSVLYLQLRMIAAIAIMC
                     GYDVKNDKVKTLAYSCLVATSSVEIVKNLGIKIGEKVAVSALKKIPGTLFVKINQAVGF
                     RLLTKFGEKGVLNIVKGIPLLGGIIGATFDILSTNTVGNIARDLFIGNTIDKHD"
     CDS             complement(8812..9891)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_9"
                     /sec_met_domain="Epimerase (E-value: 5.7e-86, bitscore:
                     278.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNTKIYVAGHHGLVGSAIWNNLQGRGYTNLVGRSHKELDLLDG
                     AAVKQFFDEEQPDAVVLAAAHVGGIMANLQYRADFIYQNLQIQQNVIGESFRHNVKKLL
                     FLGSTCIYPRDAAQPMKEDALLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGTNYIAVM
                     PTNLYGPNDNFHLENSHVLPAMIRKIHLAKCLNEGDWEAVRRDLDLRPVEGVTGSNSNI
                     EILDKLARFGITPESVTLWGTGAPMREFLWSEEMADASVHVLLNVDFKDAYTEGSRDIR
                     NCHINVGTGKEVSIREVAGMIMKEVQFKGDLRWDSSKPDGTMRKLTDVSKLHSLGWHHR
                     VEIDEGIHRLYEWYLRSEL"
     CDS             complement(9894..10991)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_10"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 5.4e-155,
                     bitscore: 506.4, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIKKVALISGITGQDGSFLAEFLIEKGYEVHGILRRSSSFNTA
                     RIEHLYLDEWVRDMKKDRLVNLHYGDMTDSSSLIRIIQQVQPDEIYNLAAQSHVKVSFD
                     VPEYTAEADAIGTLRMLEAVRILGMEKKTRIYQASTSELFGLVQEVPQKETTPFYPRSP
                     YGVAKQYGFWITKNYRESYGMYAVNGILFNHESERRGETFVTRKITLAAARIAQGLQDK
                     LYLGNLNSLRDWGYARDYVECMWLILQHDTPEDFVIATGEYHTVREFTTLAFKEVGIEL
                     RWDGEGVDEKGIDVSTGKVLVEVDPKYFRPAEVEQLLGDPTKARTLLGWNPTKTSFPEL
                     VKIMVSHDMKFVKKLHMKELMNREE"
     CDS             complement(10984..12240)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_11"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.4e-84,
                     bitscore: 273.5, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKRTIYLCLAHMSEEGIEQKYVKEAFDTNWVVPLGPNVNAFEE
                     ELKQFFGGDKEIVALSSGTAAVHLALLACGVKRGDEVIVQSFTFCASSHPVTYLGATPV
                     FVDSEMESWNMDPDLLEEVIKDRIKKTGKKPKAIVPVALYGMPYRIDRIMEIANQYEIP
                     VIEDAAEGFGSKYDGRNCGTFGKCGVLSFNGNKMITTSGGGALICADMEAKREIMFYAT
                     QAREAYPYYQHERIGYNYRMSNICAGIGRGQMTVADKHIAHHKHVCQLYKDLLKNVEGI
                     ILHENPSVHYDSNYWLNTIILDPALRVKGEEYAYNMKIQGAVGGATGVVHQASSLHTDC
                     EPNTNVEAMRLSLAKAGVESRPLWKPMHKQPVYATNPSYTNGVSELLFATGLCLPSGPY
                     VTDEDVAYIVNEIKTLING"
     CDS             complement(12267..12971)
                     /locus_tag="ctg45_12"
                     /transl_table=11
                     /translation="LTVYENMFLKFLFDRIVAFFGLLFLCPLLLVVTILIKIQMPGPVL
                     FVQKRVGKGGKIFNCHKFRSMKVAHGGSTVSVAGESRITPLGSKLRRYKIDELPGLWDV
                     FIGKMSFVGPRPDVPGYADQLEGSDRDLLKLRPGITGPASLKYRDEEEMIAKFVEKIKT
                     QDFAILNLYRNTDFTKMTDEQIAIWYNDNIIYPDKVRINCYYYRNYSLIKDIEMIFATI
                     MGRRIQYAGEII"
ORIGIN
        1 agcgtttagg tttacaatag gtgttaatca gcggagtgaa cgcattcata atcagaatgg
       61 cgaatgacat accttcggga tatgcaccga acagacggat aaccaccgtc agcagaccga
      121 tacaaacacc gtaaatcagc atacctttct tgctcatcgg agaagtcaca tagtcggttg
      181 ccataaagac agctcccagc atcagacctc cggagagtag ttgcaatatc ggagaaacat
      241 acttttcggg atccaccatg tgcataatgc ctgcaaatac aaatacagtc acaatgatag
      301 aaaccggaat atgccaggtg atgatctttt tccagagcat gtataccagt ccgagcaaca
      361 gtgccagcgc acttacttca ccgatacatc cgccgttctg tccgataaac agagtcagcg
      421 catcaggtat ctggctcaaa gcacttgcat cgccgtgaat agcctgtttc atcaatgcca
      481 gcggagtagc accggtggta gcgtccatat aagatgtcag ctgacctact accggccatg
      541 ttgtcatctg caccgggaaa gaaagcaaca agaatacacg tcccgccaat gccgggttga
      601 atgggttgca gcccagacca ccgaaagaca tcttgcctac accgattgcg aacagtgcac
      661 ccagaatgat aatccagata ggcagattgg aaggtaaatt gaatgccagc aacacacctg
      721 taatgacagc agaaccgtca caaatggttg tagcaggttt cttcattaaa aatttaacga
      781 tcgcccattc gaagaataaa caggctgcta ccgaagtagc cgtgacaatc agagccccca
      841 ggccgaagaa ataaagcgac accagaaaag ccggaatcag tgcgatcagc acaccataca
      901 tatttttctg tacgctgtct ccgccatgca cgtggggtga tagtgatacg attaatttat
      961 tttccatact tcgttatttt ttagcttgac gtgcacgaat catagctcct actttaccct
     1021 tacccaagcg gcagtaatca agcagcggac ggttggcagg acaagtgaac tgacaggaac
     1081 cgcactcgat acaatccatg attctttctt tttccattgt ttcaaaatct ccgttttcgg
     1141 acaaagctcc gagcaagtac ggctccagtc ccatcggaca agcgctcaca cactttgcgc
     1201 aacggataca ggtttgtgct tcaccacgtt tggcttcctt ctgattcata atcaggatac
     1261 cggaactgcc ttttgcgata ggaacttcga tattcaccag agccttaccc atcatcggac
     1321 cgccaccgat cacttttccc gtatcctccg gcagaccgcc acaagcatca atcagctgtt
     1381 tcatcggtgt accgatacga gccaggaagt tggaaggttt ggtcacagac ttaccagtta
     1441 cggtaatcac acgctcaaac aacggtttat ttttctgaac agcttcataa acagcaaatg
     1501 ccgtacccac attctgcaca actgccccag tagagatagg cagcgcacca cttgccacct
     1561 ggcgtttggt aatcgcatca atcaactgtt tctcaccacc ctgaggatat ttcactttca
     1621 aaggaacaac ttcgatgcct gcataactgg aagcaacttt cgtcatcagt tcaatagcat
     1681 ccggcttgtt attctcaatt ccgataaatg ccttatttac cttcacggct ttcatcagaa
     1741 tggagacacc taccatgact tcttccgcgt gttccagcat cagctgatgg tcggcagtca
     1801 gatacggttc acattccacc gcattgataa tcacacattc tgccttgaac gaaggaggcg
     1861 gacaaagttt cacctgtgta gggaaacaag caccacccaa acctacgata ccggcatcgg
     1921 caatcttctt cacgatttct tcggacgaaa gctcacattc tttgaccagt gtcttgctac
     1981 ggtcaatggt ttcttcccat tcgtcgcctt ctacatcaat aaagatagca ggttttgcat
     2041 aaccgctcgc atcgactact gtatcaatct tcgccacttt tccactgaca gaagagtgaa
     2101 ttgctgccga aacgaagccg gcaggttcgg caatcttcgt gcctaccttc accatatcac
     2161 cttttgctac tattggtttg gcaggtgcgc caatgtgctg ccccaacaga ataactgcct
     2221 ttgcaggaac ttccgctgtg atgataggtt gatgtgccga caatttattt tcgtgtggat
     2281 gaactccacc aattgaaaat gtctttaaca tacaattctg tattttattc tgttattatt
     2341 ctgttacctt cggagcttct gcagcaactg ttttcggtgc ttcttccgcc ttcggtttac
     2401 gtggagggaa gttcagctcg ataattgtgt tctgcggaca aacttccacg cacttacgac
     2461 atgatttaca cttgttcgga tcgatgtaag ccaggttgtt ctccagcgta atggcttcga
     2521 acggacaagt cttgacacac ttaccacagc cgatacagct cactgtacaa gccttacgtg
     2581 ctacggctcc cttgtctttg ttcacacaag agatgtacac acggcgtgat ttcttgcctt
     2641 gcggacgaat ctcgatgatc gccttcggac aagccttcac acaagcgcca caagctgtac
     2701 atttggcttc atccacttcc ggaagtcccg tttcaggatt catgtggata gcatcgaact
     2761 ggcaggcagc cacacagtcg ccacatccga ggcatccgta gctacaacct gtttctccac
     2821 catacaatga agcggcaata gcgcaactct tcgcaccgtc gtattgatta atacgcggac
     2881 ggttggcaca gcttccgtta catcttacta ctgctaccat cggttcagct tcagtagctg
     2941 ccagtccgag aatatcagca atttgtgcca tgacaggctg accgcctaca gggcagaatt
     3001 taccatccag cgaaccggct ttgacgcaag catcggcaaa tccgctacaa ccaggatagc
     3061 cacatccacc acagtttgcc tggggcaaca cttcccctac ctgggcaatc cgcgggtctt
     3121 catacacggc aaatttcttg gaagctacat aaagaatagc ggccagcacg agcgctatag
     3181 ctcccaatga aatcactgca atcagaatca aattcataat gttttagtta tttattggtt
     3241 ttatagtaaa tgaaaaatgt tgtttcattc gcgttttatt gagccacaat acgaaataat
     3301 aaggaataag aactgccaga gaaagaagag ccgcatacag ttcattccct atcaatgcca
     3361 tccatgcgaa cagggaaaca atcagaagta caaaaggaat tatgaatgca agggttacag
     3421 ccatcatgcc catcgacgtt tcgccgatca ccatcacccg ctctcctacc tgataggaag
     3481 cagctgtaac atccgttata tctatgattt tgtctttact atccgccgaa gaacagtgtc
     3541 cttttgcgct acaagccgca caagccgacg tctgaacgat tctcaccgac agatgagaac
     3601 cctgtatgtt ttccacaata cctagatgct ttatagtatt attcgtcatt ttgcaaactc
     3661 aacattacaa atcgcggcaa atttaatcat tatttgtgaa ctacgaagca ttccctcatt
     3721 tttttctaca taataaaatg ttattttttg tgttttcgtt atcgcacacg aaaaagtaac
     3781 gccaactatt tgatatttta gcatacaaca aagcaggcgg gaaagttctt cccgcctgcc
     3841 tgtcttatct aaccaattac tttatttact gaatgctgct tacaatgatg cagcctgtac
     3901 tcccagtact ccggcaatcg caccggctac agcaatgatt actttcaaaa ctacactcca
     3961 agttttcttc atagattttt cctcctttct tttttaagct tttcagatta tacagtcgga
     4021 tccggggctt cctcgtctcc tcccccttca tttccaccac cgccattttc accatcatcc
     4081 ggatcattcg gagtcacaga agcgttcaac ttcttcagat attcatccag actaatcaaa
     4141 tccagttttt catctgcacg ggtagccgtc ttcgtgatac gcagttcctt attcgcctga
     4201 aagaaaatgc gtacgctatc cacactttta gcattgacat ctttcgctgc atccgctcct
     4261 ttcgaacaag cagtcagcat aaatacaccc aagccttcga tattcacaga cttaccttcc
     4321 aaaagttgct ctttcatttt ctccacaaaa ttctgaatca cactcttgat atcaccgatg
     4381 gataaagaag aatagccctg cattttctgc gcaatatatt tcagattgac agactgacct
     4441 aaagtaatca gatgcggata atatttcttg ggagaattgg gaacacgcgg gtcagatggt
     4501 cgcgtaacaa ccttgtaaat tacactcata atacgttttt ttaaagattc aaattcaagt
     4561 tattttattc acgttttgtt gatcaacaat gcaaaggtga ggcttttatt tcagataaca
     4621 aaaagaaaag ccccttgcgg ggctcttttt ctgagaaaag ttataattca tagatattca
     4681 gatatttatc tttttgtatc ttggccatat ccatagccgt aaccataacg tttaccatat
     4741 ccgtaatgct tgccatactt accgtaaccg tagtaataac catattttcg cttcttcagg
     4801 tctacgccgt tgatgacggt acaaagatta ggcagcttct tctcaaaaga cagttcattg
     4861 atcaatgtat attccgcctt atgagtgtag tcagcacggc atacgtaaac tgacaagtct
     4921 gctacacgac ctattaataa ggtatccgtt accatgccga taggagcagt atcaaggatg
     4981 acataatcga agttcttctt caaagtttct atcgctctgt ccaaaccgtt acgagccaac
     5041 agttccgttg gattaggagg aacagtacca cccggaagaa taaacagatt cttatttaca
     5101 tcagaaggtt gaacaagctc catcaaatcc atttcagggt tggaaagata ctgagtaata
     5161 cctctctcct tattagagag ctggaatact ttattcagtc ctggcttacg aatatcgagt
     5221 ccgacaatca ccactttctt tcccaaaaga gaaagactga tagccaggtt cgacgaaaca
     5281 aacgattttc cttcaccact gacagtcgag gtcacaagga taaccttctg atcattatcg
     5341 agcataaact gaagattggt tcgaatatta cggaaggttt cactcatcag attattcttg
     5401 ttctcgaaga cagcaataga accattctta tcattcttct catcagttaa tggaatatca
     5461 ccgacaacag gaacactcgt tagtttctcc acatcggcac gaccttcgat cttgaatttc
     5521 gtcagttcaa tcaggtagat gataccaacc ggaattccaa caccaagtat caatgcaatc
     5581 aaatagatca tagagcgttt aggagatatc ggaatatcat ccgctatcgc ttcatcaatg
     5641 atcttcgcat tattcgcagt ggcagcaagc gcaatagcat tctcttcacg tttctgtaac
     5701 aacatcagat acaatccggc cttgatctcc tgctgacggg cgatgcttac ataagcacgt
     5761 tcctgtcccg gagcgttact gatacgacgg gaatagcggc tcgcttcacg gtcaaggctc
     5821 tctttggtga tcatcaaccc ctgcaaggtt ccttcaaggg tagcctgcac attggctttc
     5881 atagcacgga tacttgtatc tagattcaca atcgtgggat tattttctgt tgaggtccgc
     5941 aacaggcgtt tacgttccat caacatctcg ttgtaacgtt caatagctcc aatcaaggca
     6001 gcatcctgca aacctacgtt actcggtaat acttcatatt cattacctct cagatactta
     6061 ctcaaatcat ttaccaggct gatttgagta cggttctcca cactcttctt ttcatattcc
     6121 gcattaccgg ccaaggctat ctgagcttca ctcgtcaagt ccgtgatacc ggcatcacgc
     6181 ttgaaagtct ctaaattagc ttccgtacta cccaattctt ttgagataat gccaatacgt
     6241 tcatcgataa attctgctgt tttctgggca atctcgttct tatcattgtt cgtattgcga
     6301 ttatacattt caagcaactg gttaataaaa tcctgcccac gccgcaaact ggagttcttc
     6361 aacgaaatca cagctacgga agtagtctta gaagtaggtg caatagacag gctgttacaa
     6421 taacctcttg ctactctcat cggcttgttt attgtcgcag ttatatgacg tacactcttc
     6481 tctatccgag gaactttcgt tccatcctgc aaggttaccg aatcagctgc ctgaaagaaa
     6541 gccagcgtac cttcatctgt cgggaagata gcaggcagct tttcaaaatg cttctgatag
     6601 cctttctcac ctatagtcac atttacatcc atactacctt caggctgtaa ggtcatttct
     6661 actatcatcg gtgtagttaa tttctcagcc tcctgaggag ttaggctcac ctgcaccgga
     6721 gatgtcttat ataaaccttt agcgggaaac tcatcctcat ctttataagt tatatacaat
     6781 cccaactgat tcacaacctc ttttacaaga gttttcgaac gcagtacctc cagctcgtta
     6841 tcaatgtttt tagaagaagt catcagacca cttaacccca tatcttccaa ttccgaagaa
     6901 agtcctgcac ctccgccctt cttctcatct tttattaaga cggtagcgga aatattataa
     6961 atgggtgtag cccaatgcaa ataaaaccat gcaccaacaa aacatagcaa cacagcacct
     7021 acaaaccacg gccagtgaat aatatattta aaaaacaacg cccggaaatc gatctgatcc
     7081 tcagctattt cacgttcctt cacgttttga ttttcttcct tcataaccct tccttttatt
     7141 tcaaaatatt aaacaacaaa ctagcaatag aaacaaggat cgaagtagca gagaaccata
     7201 aacttgtact agtaccgata tccgaatttc gagctttcgc cttattcgga gttacgtaaa
     7261 taatatcatt ctgttgcaaa taataataag gagaaagaat agtctccgcc ttattcagat
     7321 ccaaaggaat aatttcctgc ttaccattgg cattctcccg tatcagctta acatcatcac
     7381 gcagaccata tacggtcata tcacctgcca tagccaaagc ttccaaaata ttcacctttt
     7441 cattggaaat cgtgaatgta ccgggacggg caacttcacc aatcacggaa atcttataat
     7501 tcaccatacg taccgttaca ataggcgtct ctgttatata aggtttcaac ttttccacaa
     7561 tcatctgttc agtcgctttc tttgtcaatc cacccacatg aagttcgccc aataccggaa
     7621 agttgatatt accttcatta tccaccagat attgctgcag gactggctga gtagtcgtat
     7681 aattcaaagc agcattactc tgtgtagcca ctgtcagatt aaaaggcgca gccagttcag
     7741 gactggtaca cgacactaca atagtcaaca agtctttggg catgatcttt gcatcatata
     7801 actgttcgtt ctgagtacta tacagtacca cttccgcatc ctgtaaataa ggtacttttt
     7861 tataagactg gcatgctgtc aacagaaaaa ctgacaatac gcaatagact aattgtttta
     7921 ttctcttcat atatttcttt caatagtttt tatactaact ttattaatat ccaatattgt
     7981 tttatatagt tcataaacgc gttgtagtca cctttgcatt taaacaataa atagatatta
     8041 aattttaatc atgtttgtct attgtgttac caataaacaa atctcttgct atattcccca
     8101 cagtattagt tgaaaggata tcaaatgtag cacctataat tccacctaaa agtggaatac
     8161 ccttgactat attcaaaacg cctttttcac caaattttgt aagtaatcta aagccaacag
     8221 cctgatttat tttaacaaaa agagttcccg gaatcttttt taaagcacta actgctactt
     8281 tctctcctat tttgatccct agattcttta caatttcaac cgaagaagta gcaacaaggc
     8341 aagaataagc caatgtttta actttatcat tcttcacatc atatccacac attatagcaa
     8401 tagcagcaat catacgcaat tgaagataca aaacggaagt tatattaacc ggtaaagtta
     8461 ttggtatggt taaaaatcct cctaatcccg taacgaaacc tgaagtcccc gcttttgcat
     8521 tttgccaacg gattaaagca tttatctgat ctaataaaga accgtcttgt gtcaaataat
     8581 ctttcgctaa ttcttcagca gaatccaatc cctttactcc atttaccgcc ttatcataag
     8641 cccaatctaa agattgcata atcattttgt gactaagatt tcctaattca ttttccataa
     8701 tattattttt ttattggtga aattactcta gcacccagta aataatcaat aagtttgtgt
     8761 ctatttatca atacataaaa agcaagtaag cgtgctaacc ttaccatcac cctataattc
     8821 acttctcaaa taccattcat aaaggcgatg aataccttca tcaatctcaa ccctatgatg
     8881 ccagcctaaa ctgtgtaact tcgacacatc tgtcaacttg cgcatcgtac catcaggctt
     8941 tgaactatcc caacgcaaat cacccttaaa ttggacttcc ttcatgatca ttccggcaac
     9001 ttcacggata ctgacttcct tacctgtacc aacattgata tgacagttac gaatgtctct
     9061 actaccttcc gtataggcat ctttaaaatc aacattcaat aatacatgaa cactcgcatc
     9121 ggccatctct tcactccaca agaattcacg catgggtgca ccggtacccc aaagtgttac
     9181 agactcagga gtaataccaa acctagccag tttatccaat atttcaatat tagagttact
     9241 gccagtcaca ccttccacag gacgcaagtc aaggtctctg cgaactgcct cccaatcacc
     9301 ttcgtttaaa catttagcca gatgaatctt gcgaatcatg gcaggtagaa catgactatt
     9361 ttccaaatgg aaattatcat tcggcccata aaggttggta ggcatcacgg caatatagtt
     9421 cgtgccatac tgaagattga agctttcaca catcttcaaa ccggcaatct tggcaatggc
     9481 ataaggttcg ttcgtatatt ccaaaggaga agtcagcaaa gcgtcttcct tcatcggctg
     9541 tgcagcatca cggggataga tacaggtact acccagaaaa agtagtttct ttacgttatg
     9601 acgaaaactc tcaccgatca cattctgttg aatctgaaga ttctgataaa taaagtcggc
     9661 acggtactgc aagtttgcca taataccacc gacatgcgca gcggcaagga caactgcatc
     9721 aggctgttct tcatcaaaga attgttttac ggctgcacca tcaagaaggt ccagctcttt
     9781 atgggaacgt cctaccagat tcgtatagcc acgaccctgc aaattattcc agatagcgga
     9841 acccaccaga ccatggtggc ccgctacata gattttcgta ttcttatcca ttcttattct
     9901 tctctattca tcagttcttt catgtgaagc ttcttcacaa acttcatatc atgcgatacc
     9961 atgattttta ccagttcggg gaaagaagtt ttggtgggat tccagccaag taatgtacgg
    10021 gctttcgtag ggtcacccaa taactgctct acttcagcag gacggaaata tttaggatcg
    10081 acttcaacca ggacttttcc cgtcgataca tcaatacctt tctcatccac accttcaccg
    10141 tcccaacgaa gttcaatgcc gacttctttg aaagccagtg tcgtaaattc acgtacagtg
    10201 tggtattctc ccgtagcaat tacaaaatct tcaggagtat cgtgctgaag gatcagccac
    10261 atacattcaa catagtccct ggcgtatccc cagtcacgaa gtgagttcag gtttcccaga
    10321 taaagtttgt cctgaagacc ttgtgcaata cgggcagcgg ccaatgttat cttacgggtt
    10381 acgaaagtct cgcctctacg ttcactttca tgattaaaaa ggattccgtt tacagcatac
    10441 atgccatagc tttcacgata gttcttggtg atccagaaac cgtattgctt ggctactcca
    10501 tatggggaac ggggatagaa tggagtagtt tccttctgcg gaacttcctg taccaaaccg
    10561 aatagttcgg aagtggaagc ctgataaatg cgtgttttct tttccattcc aaggatgcgg
    10621 acagcttcca gcatgcgaag tgtgccgata gcatccgctt cggctgtata ctccggtaca
    10681 tcaaaagata ctttcacatg gctttgagcg gccagattat aaatttcatc cggctgtacc
    10741 tgctggatta tacggatcaa agaactggaa tccgtcatat ctccataatg aagattgacc
    10801 agacggtcct ttttcatgtc acgcacccat tcatccaaat aaaggtgttc gatacgtgca
    10861 gtattaaaag aagaagaacg acgaaggata ccatgtacct catatccttt ttcaattaga
    10921 aactcggcta aaaatgaacc atcctgaccg gtgatccccg atattaaagc tacctttttt
    10981 attttatcca ttaatcaaag tttttatttc atttacaata tatgcaacat cttcatcagt
    11041 tacataggga ccactcggca aacaaagccc cgtagcaaaa agtaactcac tcactccatt
    11101 tgtataactc ggattcgttg catagacagg ttgtttatgc ataggtttcc acaaagggcg
    11161 agattctaca cctgctttag ccaatgacag acgcatggcc tctacatttg tatttggctc
    11221 acaatccgta tgtaaagaag aagcctgatg taccactcca gttgcaccac ctacagctcc
    11281 ttgaatcttc atgttataag catattcctc accttttact ctcaatgctg gatcaagtat
    11341 tatagtattg agccaataat tactatcata atgtaccgaa gggttctcat gtaaaataat
    11401 accttctaca tttttcaaca gatctttata aagctgacaa acgtgtttat gatgagcaat
    11461 atgcttatca gccacagtca tctgtccacg ccctatacct gcacaaatat ttgacatacg
    11521 ataattatag ccaatgcgtt cgtgttggta gtaaggataa gcttcacgtg cctgagtagc
    11581 ataaaacatt atctctcgtt ttgcttccat atccgcacaa ataagagctc caccgccaga
    11641 tgttgtaatc attttattac cattaaatga aagtacacca catttaccaa aagttccgca
    11701 gtttctacca tcatatttac taccaaatcc ttccgcagca tcttcgatga caggaatctc
    11761 atattgattg gcaatctcca taatccgatc tatccgatac ggcattccat acaaagccac
    11821 cggaacaatt gctttcggtt tctttcctgt tttttttata cgatctttaa taacttcttc
    11881 caacaagtca ggatccatat tccaactttc catttcagag tcaacaaaaa caggagtagc
    11941 tcctaaataa gtcacaggat gagatgatgc acaaaatgta aacgactgca caataacctc
    12001 atcccctcgt ttcacaccac aagccaacaa agctaaatgt acagcagccg ttccagaaga
    12061 caaagcaaca atctctttat ctccaccaaa aaattgtttt aattcttcct caaaggcatt
    12121 cacattaggt cccaaaggca ctacccaatt agtgtcaaat gcttccttaa catatttctg
    12181 ttcaataccc tcttctgaca tatgtgccaa acagagatag attgttcttt tttccgacat
    12241 aattacactg aattaaatta ttttttttaa attatttcgc cagcatactg aatccgtctc
    12301 cccataatag tagcaaatat catctcaata tcttttatca aactgtagtt acgataataa
    12361 taacagttta tgcgaacttt atctggataa ataatattat cgttatacca aattgcgatt
    12421 tgttcgtcag tcattttagt aaaatctgta tttctatata aattaagtat agcaaaatct
    12481 tgtgttttta ttttttcaac aaatttcgct atcatttctt cttcatccct atatttaaga
    12541 gatgcaggtc ctgtaattcc tggtcggagt ttcagtaggt ctctatcaga tccctctaat
    12601 tggtctgcat accccggaac atctggacga ggccccacaa aactcatctt tccaataaag
    12661 acatcccata agccaggtaa ctcatctatc ttatatctgc gaagttttga gccaagtggt
    12721 gtaatgcgac tttcacctgc tacacttact gtagacccac catgagccac cttcatcgaa
    12781 cgaaatttat gacaattgaa gattttccct cccttaccta cacgcttctg tacaaacaat
    12841 acaggaccag gcatttggat tttaattaaa atagttacta ctagtaatag agggcacaaa
    12901 aacaacaaac cgaaaaatgc cactatacgg tcaaaaagga attttaagaa catattttcg
    12961 taaactgtca acaatactca cattttaata tacagcacat tagtctacca atctaaatca
    13021 ttataaaaag acaaagccat ccttcagtta ttagagattt ttagaagact tttccttcta
    13081 ttgaatcaat atctccacac atttccaact aatgtgatca tcaagttcaa taccaatgag
    13141 caaaaatggt atttgtcctg tcaaagccat attatttatt aagtttgtca cgtaaaatac
    13201 ttgaggatat accgtca
//
