LOCUS       c00057_gnlPro..        13577 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKFEMOPI_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:50:28
            Original ID  :: gnl|Prokka|CKFEMOPI_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 141402
            Orig. end    :: 154979
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13577
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[151402:154916]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13577
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13577
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(454..1581)
                     /locus_tag="ctg57_92"
                     /transl_table=11
                     /translation="MEKPFVFGVATSGDNFTDREKETQRLLLNFTHGVNTILISPRRWG
                     KTSLVKKVAQLAQTKTRKIVYLDIFSCRTESEFYRLFATSVLKQTSSKWDEWVENTKQF
                     LAHINPKISIGTDPMNDFSISFEYSMQDNAGNDILQLPEKIAIEKGIQIVICIDEFQQI
                     SDFEDSKTFQKKLRTVWQLQQHVSYCLFGSKKHLMNELFEKKNLPFYKFGDAIYLTKIE
                     TKYWIEYICKRFENTGKHISPELAKEICRLVDNHSSYVQQLAWLLWIRTTDIATEEQLT
                     HALEDLLDQNNILFQSETENLSAYQMNFLKAVIDGIHSKFSSKEIILKYNLGTSANIVR
                     LKSALLQKELIETDGKEIILADPVFGVWFKKEVSC"
     CDS             2745..4022
                     /locus_tag="ctg57_93"
                     /transl_table=11
                     /translation="MKNGIYTCIILMAFLALSESVYAVVPVLTVASDTIRRVVIYFDQE
                     ETDVDFCYKTNNQEINVLDSLLEERINSRYITALNVVTFVSPDGDSVYNAALSVRRNNS
                     MREFLRQRYPYVDVEKIKLTSEGEDWSELRKLVASDSDLPDREEVLMLIDYHRDNTVKR
                     KELLQKLNQGMAYRYIVRNVLPKLRRAEITVVREVPEMEKNTFEPVSSVSGLFVSKQEE
                     ALPSDQPDKPEGESKESMAYEVVVSEAEGPVESKTVLAVKNNLLYDLALAPNLEVEIPV
                     GKRWSLNAEYKCPWWLNSKHDFCYQLLSGGVEGRCWLGNRQKRNRLTGHFVGLYAEGGT
                     YDFQWKGDGYRGDYYGAAGVTYGYARQLARHLSLEFSFGIGYLTTEYKKYTPYEGDIVW
                     TTSGRYNFIGPTKAKVSLVWLIKRGR"
     CDS             3998..4993
                     /locus_tag="ctg57_94"
                     /transl_table=11
                     /translation="MADKKREIRTLCKIQDTRYILLVLLSSLLMLTGCSRRELLDDYPV
                     SGVDIKLDWNGVTDKLPEGVRVIFYPKSAEGRKIDTYLSVRGGKVKVPPGRYSVVAYNY
                     DTETVQIRGEEAYETIEAFTGYCNGLGIAGTEKMVWGPDPLYVVQIDDLHIANSEEELL
                     LDWKPKLVVKTYSFKIKVEGLEYVSSIVGSVEGMAGCYCLGRCCGMMNDAPIYFEAQGR
                     SGEVTGSFTAFGLPEGAMSRASLAIKFTLAFVKVDNTVQKIEVDITDVIVNSESGEGGG
                     NDEPSKDIELPLDDDEVKVDKPENSSGGDGGIGGDVGDWGEEEEVPLPVI"
     CDS             5046..6074
                     /locus_tag="ctg57_95"
                     /transl_table=11
                     /translation="MKKVLLAIAAVATITSCSQNEEFENPNQQAKIGFTSVVKKATRAT
                     DTTTDNFLAFTVSSYVTSATYDGTTLLGNAYMNGVSYTKANAASVWSTEDAGSYYWPSL
                     DSEKKVQFFAYPTTVKSSYSVPTVDPVAPATGYPSISFEVNATPANQIDLVVAHAANVV
                     NSTDAGVSADGKLTLDFKHVLTRVNFAYIPGDLNLTYTVTAISIADIQGGTAKYNFDAS
                     DGNWDLTGTTKVNSYSYDVKQSAEKVAGKEYYSLADADASWMLLPQKVNGKIISISYST
                     KQGEMEVYKGTKTVTLPANAEWEVGKNVLYILTLPAGAAKVQIDTKVNGWNNATETPES
                     AK"
     CDS             6259..7101
                     /locus_tag="ctg57_96"
                     /transl_table=11
                     /translation="MSSICQGTWDCQNCPKAVDNAIIHITHTRGYHQPARKCEDNFILF
                     LIKGELLVNSQEYAGTMLKAGEFILQAIGSKYEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKDVPSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLSYYYSD
                     YDLASLVHPLSKYTTTFEYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFHEPVYE
                     WMQARRKEGILDDLNNSEYSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTSKKNV"
     CDS             7448..8974
                     /locus_tag="ctg57_97"
                     /transl_table=11
                     /translation="MRTNRAFKGFCVLGGLASSVCGVAQERPNIIVFLVDDMGLMDTSV
                     PFIADESGQPVRHPLNDWYHTPNMERLAKQGICFSTFYAQSVSSPSRASIMTGQNATRH
                     GVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPKVLQQAGYKTIHVGKAHFGCMGSEG
                     ENPQNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTI
                     EANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMD
                     KSLGDIMDQLEKLGIAENTLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRV
                     PFIAAWAKPEKKSKVQKNLPIEVGSMQTQLGTIMDIYPTVLSVAGCEVPQNYVIDGFDL
                     KKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLK
                     DDPEERNELSSAHPDKCREMIQEMSAQLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(9152..9376)
                     /locus_tag="ctg57_98"
                     /transl_table=11
                     /translation="MTEIMLDKQETLNEIGTKIRKLRESKNLSIQEFADKLEMEYNNVI
                     RIEKGRTNFTIGTLVKIANTLEVNLKDIV"
     CDS             9501..9893
                     /locus_tag="ctg57_99"
                     /transl_table=11
                     /translation="MDTLNLHSNFDNLLYIGRSVLNNTSSHIQKLFFKKEMCIYEYLYK
                     EEVSKGIEIKIDDVVLVCALEHDKCNKSILYFNDVANIARYIHYCNSNFEYKEELNGWI
                     MSDSYLALSISEDDYEKRFAFIQTLL"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_100"
                     /sec_met_domain="Fer4_7 (E-value: 7.5e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 5.3e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_101"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-61, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.5e-36,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13514)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_102"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-130, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
ORIGIN
        1 aaatagaaat agaagatgct atctgttttt gcgattattt caatttgcat atacatttag
       61 ctacgcatcc ccagtcgtgt gaatacttcc tgccaatatg ggaaagagga aagttgctgg
      121 agaatatcga gcattcattg ttcgataagt ataagcaacg ttcggaagac actattcttt
      181 cattgcttcc taaggatttg ccggtttatt atcagcataa tgaatatcgt tatgtgttgc
      241 gcatctgttt cattattctg aatagagatc cgttgaatga gaaagcattg atgtatagtg
      301 tcagatgcta taaaaagatg aatgactttg agaatctttc caaaatatac tcggctttca
      361 ttattgaata tcgtaaaagt atgggagagg actataccca aacgatagaa gatttgcttt
      421 tggaagagag ttaatcaatc atttgttttt atatcagcat gatacttctt ttttaaacca
      481 tacaccaaat acaggatcag ccagaatgat ttcttttccg tctgtttcta ttagttcttt
      541 ttgtagtaat gcactcttca gccgaacgat attggcagag gttccgaggt tatattttag
      601 aatgatctcc ttactgctaa atttagagtg tatcccatcg atgaccgctt ttaggaaatt
      661 catctgataa gcggagagat tttcagtttc gctttgaaaa agaatattgt tttggtctag
      721 taaatcttcc agagcatgag tcagctgttc ctctgttgct atatcggtgg tgcgtatcca
      781 aagcaaccag gcaagttgtt gtacgtagga agagtgattg tccacaaggc gacagatttc
      841 tttggcaagc tcgggtgaaa tgtgcttccc ggtattttca aagcgtttgc agatatattc
      901 tatccaatat ttagtctcta ttttggtgag atagatcgca tctccgaatt tgtagaatgg
      961 aagattcttt ttttcgaaaa gttcattcat cagatgtttc ttacttccaa aaaggcaata
     1021 tgagacatgc tgctgtagtt gccacaccgt acgtagcttt ttctgaaatg tttttgaatc
     1081 ctcaaaatct gagatttgtt ggaactcgtc aatgcagatc actatttgaa tccctttttc
     1141 tatcgcaatc ttttcaggta attgcaagat atcatttccg gcattatcct gcatgctata
     1201 ctcaaaagag atagaaaagt cgttcatagg gtctgtgcca atggaaattt tgggattgat
     1261 atgtgcgaga aattgtttgg tgttctcaac ccactcgtcc catttggaag aagtttgttt
     1321 taatacagaa gtagcaaaaa gacgatagaa ttcgctttcg gtacgacagg agaaaatgtc
     1381 taaatagact atctttctgg tctttgtttg agctagctgg gctactttct tcacaagcga
     1441 tgttttcccc catcttcttg gggatataag tattgtgttc acaccatgtg tgaaattaag
     1501 gagcagacgc tgggtttctt tctctcgatc ggtgaagtta tctccggaag tggctacacc
     1561 aaaaacaaat ggcttttcca tgcttatctt tttgttggaa ccttgcaaat atagcgattc
     1621 tttaataaac taacaagttt gttactaaca aagttgttag taacaaactt gttagtcatt
     1681 gacgatgcaa cctttgttta tatgccagtg ttccaattat ttaatttgta attaacgctc
     1741 gaagggcttg aggacttaac aaaggctttt ttatgtaact ttgtagtcgt aataacaaca
     1801 ataaaactca aattaaaatc tggaatctgt cggatcgcat tgataacttg aattcaacat
     1861 gccacacagt gatttgatag tagttttgct ctcatgctct aatgaaaggt ctgtattcct
     1921 ttattcatcg tagtttcagg tatggtagca agtgtggtgg caggtatgag agcaagcgtt
     1981 tgctctcact cttccatata tcattgtttg tcatttgttt gatattatct tttgatttac
     2041 aggatgttaa taactgaagt gtcaactatt aatgattggt atatcagaca ttaataaatg
     2101 agaaatcagc ctttaatggt tgataactca gttgtttttg actgataaat gatttattgt
     2161 ttcttggaag agcaggttaa tcgaacagtt gttacggtca agttaattga atcatataag
     2221 taagccatca gtttcctgcc ttggatactg cagtgtcccg ccttgggaac tgcagtatct
     2281 tgccttggga actatcgttt cccgccttgg gaactatcgt ttccttcctg gatactgtcg
     2341 tttctgcttc ggaaatcatt tctccgataa taggaggtta tcttccattt ccgatataag
     2401 cggcgccttc cctgtttata ccggtgttgc agatggtggt atctgtcact tatctgcaac
     2461 aggtatctgc aacgctgtaa tcaaatgttg attaaatagt tatttcgatt ttgttgcaga
     2521 tggcagatgt ttttcattta taacttctgt gtagtatcgt ggaaaaatag cttttcaact
     2581 tctggagttt cgctttttta cgcttgttct atccatccat actcttaaaa cttgcaaatt
     2641 ccttccaatc gtttcacaga accttccaag cctgtttttt tgttccggta gtatgatttt
     2701 atttagttat taacttctat atttgttcac agaaacgaac aattatgaaa aacggaatct
     2761 atacatgcat tattctcatg gcatttcttg ctttatcaga aagtgtgtat gcagtggttc
     2821 cggttctcac ggttgcgagt gacactatca ggcgggtggt gatatatttc gatcaggaag
     2881 aaacagatgt tgatttctgt tataaaacta ataatcaaga aattaatgtt ttagattctt
     2941 tgcttgagga aagaataaat tcaagatata tcactgcgct caatgtggtc acttttgtat
     3001 cgcctgacgg agattcggtt tacaatgccg cattatctgt ccgaagaaac aattcgatga
     3061 gagagttctt aaggcaacgt tatccgtatg ttgatgtcga aaagattaaa cttacttctg
     3121 aaggagaaga ctggtctgaa cttcgtaagt tggtggcgtc ggattcagac ttgccggacc
     3181 gggaagaagt cttgatgttg atagattatc atcgggataa cactgtgaag cgaaaagaac
     3241 tgttgcagaa gttgaatcag ggaatggctt accgatacat tgtccgcaat gtgttaccta
     3301 agttgagacg cgctgagatt acggttgtcc gggaagttcc ggaaatggaa aagaatactt
     3361 ttgaaccggt atcttctgtc tccggattgt ttgtttcaaa gcaggaagag gcgcttccga
     3421 gcgatcaacc tgataagccg gagggagaaa gtaaagagag tatggcttat gaggtggtag
     3481 tgtcggaggc agaagggccg gttgaaagta aaacggtgct tgcagtgaag aataatctgt
     3541 tgtacgactt ggcgttggcg ccaaatctgg aagtagagat tccggtaggc aaaaggtggt
     3601 ctttaaatgc tgaatacaaa tgtccgtggt ggctgaacag taaacatgat ttctgttatc
     3661 agcttctttc gggaggagtg gaaggacgtt gctggttggg caatcgtcag aagcgcaacc
     3721 ggttgacagg acattttgtt gggctttatg ctgaaggtgg aacttacgat ttccagtgga
     3781 agggagacgg ttatcggggc gattattacg gagctgcggg agtgacctac gggtatgcgc
     3841 ggcaactggc tcgccatctg tcgctcgaat ttagcttcgg catcgggtat ctgacaacag
     3901 aatataagaa atatactcct tacgaggggg atatcgtgtg gacaactagt ggacgttata
     3961 actttatagg tcctaccaag gcgaaagtct ctctggtatg gctgataaaa agagggagat
     4021 aaggacgtta tgcaagatac aagatacaag atacatactt cttgtgcttc tgtcctcgct
     4081 actgatgctg accggatgta gccgtcgcga actattggat gattatcccg taagcggggt
     4141 agatataaag ttagattgga acggtgttac cgataagttg ccggaagggg ttcgggtgat
     4201 tttttatccg aagagtgcgg aaggcagaaa gattgataca tacctttcag taagaggtgg
     4261 aaaagtaaag gtgccgccgg ggcgttactc ggtagtggct tacaactacg acactgaaac
     4321 ggtgcagatc agaggagagg aagcctatga gacgattgaa gcattcacgg gctattgcaa
     4381 tggtctggga atagcgggaa cggaaaaaat ggtatgggga cctgatccct tatacgtagt
     4441 gcagatcgat gatttacata tagcgaacag tgaagaagag cttctactgg attggaaacc
     4501 gaaattagtg gtaaagacct attctttcaa gatcaaggtg gaagggctgg aatatgtttc
     4561 ttcaatcgtt ggcagtgtgg aaggcatggc gggttgttac tgtttgggca gatgttgcgg
     4621 gatgatgaac gatgctccta tctactttga agcgcaaggg cgttcgggcg aagtaacggg
     4681 tagttttact gcttttgggt taccggaagg ggcgatgagt cgggcaagtc ttgctataaa
     4741 gtttacgctg gcatttgtga aggtggataa tacggtacag aagatagagg ttgatataac
     4801 ggatgtgatt gttaattcgg agagtggtga agggggaggc aacgatgagc cttctaaaga
     4861 tatagagtta ccgcttgatg atgatgaggt gaaggttgat aagccggaaa attcgtctgg
     4921 tggtgatggt ggtattggcg gtgatgttgg tgattgggga gaagaggagg aggtgccttt
     4981 gcccgtaatt tgagataaag cataagcaaa atataacaat attataaact taaaaaaata
     5041 cgattatgaa aaaggtatta ttggcgattg cagcagttgc aacaattaca agctgctcac
     5101 agaacgaaga atttgagaat cccaatcaac aagcaaaaat tggttttact tcagtagtga
     5161 agaaggcgac aagagccact gatactacca ctgataattt tttagctttt acggtaagtt
     5221 cttatgtaac aagtgctacc tatgatggta cgactctttt aggtaatgca tatatgaatg
     5281 gagtttcata tacaaaagca aatgctgctt cagtttggag cacggaggat gccggctctt
     5341 attattggcc atcattggat tcggaaaaga aagtacaatt ttttgcgtat cctactacgg
     5401 tcaaatctag ctatagtgtt cctactgttg atccggttgc tcctgctact ggttatcctt
     5461 cgatttcttt cgaagttaat gctactcctg caaatcaaat tgatttggta gtagcacatg
     5521 ctgctaatgt agttaattca acggatgctg gtgtaagtgc agatggtaaa ttgactttgg
     5581 attttaaaca cgttttaact cgcgtaaatt tcgcatatat tccaggggat ctaaatctta
     5641 cttatactgt aacagctatt tctattgctg atattcaagg cggtacagcc aaatataact
     5701 ttgatgcatc agatggcaat tgggatttga cagggactac taaagtgaat tcttattctt
     5761 atgatgtaaa acaatctgct gagaaggtgg caggaaagga gtactattca ttagctgatg
     5821 ctgatgcttc ttggatgcta cttcctcaaa aagtaaatgg aaaaattata tcaatatcgt
     5881 actctactaa gcaaggtgag atggaagtat ataaaggaac taaaacggtg actctacctg
     5941 ctaacgctga atgggaagtt ggtaaaaatg tattgtatat tttaacatta ccagctggtg
     6001 cagcaaaagt tcagatcgat acaaaggtta atggatggaa taatgcaaca gaaactcctg
     6061 aaagtgcaaa ataattatag agtataagag attcttttag ttttgaactg tataaatcat
     6121 ctggatttat acagttcttt atcttatagc tatatatacg caaccttttt tcacttttct
     6181 tcccttttct attgccatct aaaagatttc atatattttt gttgcaaaca ggaacaaatc
     6241 aaacgccaac acaaatatat gtcatcaatc tgtcagggta cttgggattg tcagaactgt
     6301 ccgaaagccg tagacaatgc tattattcac attactcata caagggggta ccatcaacca
     6361 gcccggaagt gtgaagataa tttcatcctt tttttgataa aaggagagct cttggttaat
     6421 agtcaggagt atgcaggtac gatgttgaaa gcaggtgaat ttattcttca ggctattggt
     6481 tcaaaatacg agatgcttgc gatgaccgag tgcgaatgta tctattatcg ttttattcag
     6541 ccggaactat tctgtgactt ccgtttcaat catatcatga aggatgtacc ttctccgctt
     6601 atctattctc ctttaaagat aattcctgaa ttgaaatact ttttggatgg ttccaaatcc
     6661 tatttgagtg aaagtaaagt ctgccgggat ctgctgtctt taaagcgcaa agaactggcg
     6721 tttgtgctaa gctactatta ttcggattat gacttggcta gtttggtgca tccactctcg
     6781 aaatacacca ccacttttga atacttcatc cttcagaact ataagaaagt aaaaacggta
     6841 gaagaactgg ctcaactggg aggttatacc gtcagcacct tgcggcgtat cttcaataat
     6901 gtattccacg aaccggtata cgaatggatg caggcgcgac gtaaggaagg cattttggat
     6961 gacttgaata actctgagta cagtatctcc gaaatatgct ataaatacgg ttttgagtct
     7021 ctgcctcact tctccaattt ctgtaagaag ttctttggag cttctccacg tatgcttaga
     7081 acaagcaaga agaacgtctg ataatttttc agagagaaag tcaaaaacta tttttttctt
     7141 tgcgggtata gtacatttgt tgtatattgc tagctgtttc ccttaaaacc agtctaatac
     7201 atctttatta taaagtcaga tcacttcaaa taaagccatg ataaggcgga tacggaaatt
     7261 aaacttttta tttcaacgaa ttaaaatcag gtttcaaagc agaataataa catgatagat
     7321 tatgctgaat gaatgaaaga taataggata tttttctagt actcttttgt gtaatcagaa
     7381 gggagtcaag gtttgaaatc tattatggca cgtacaataa ctaggatata aatcaaaaaa
     7441 ctatgtaatg agaacgaatc gagcttttaa aggattttgt gtgctgggtg gtttggcatc
     7501 ttccgtttgc ggggtggctc aggaacgccc gaatattatt gtcttccttg tagatgacat
     7561 gggacttatg gatacttcgg ttccttttat cgcagatgag agtggtcagc cggtgcgtca
     7621 tccgctgaat gactggtatc atactccgaa tatggagaga ctggctaaac agggtatttg
     7681 tttttctact ttttacgcac agagcgtgag ttccccttcc agagcttcca tcatgaccgg
     7741 acagaatgcg accaggcatg gagtcactaa ctggattaat gccgagagca acaaccggaa
     7801 tcctttcgga ccgccccaat ggaactggaa aggtcttaga aaagacatgc ctaccatgcc
     7861 gaaagtcctg caacaagccg gatataaaac cattcatgta ggaaaagcgc atttcggctg
     7921 catgggcagc gaaggagaga atccgcagaa tatcggcttt gatgtaaaca ttgcaggttc
     7981 cggcatcgga catcccggca gctattatgg cgaatggggc tatggtcata tcaagggaca
     8041 gaagattaga gcggttcctg acttagagaa atatcacggt acagacacat tcctgagtga
     8101 agcgctgact atagaagcga atcgggaaat caccaaagcc gtagaagaaa aacggccttt
     8161 ctatctgaat atggctcatt acgcagttca ttcacctttc caggcagaca aacgtttctt
     8221 gtcacgctac accgacccgg ataagaacga gcaggcaaga gcttttgcta cattgataga
     8281 aggcatggat aaatcattag gcgacatcat ggaccaactc gaaaagctgg gaattgccga
     8341 aaatacgctg attctctttt taggagataa cggtggtgat gctccattgg gagatgaacg
     8401 tggctatggt tcttccgctc cgctgagagg taaaaagggg acggagtttg aaggtggtat
     8461 gcgtgttcct ttcatcgcag cttgggcaaa gcctgagaag aagagcaaag tacagaagaa
     8521 cttgcctatt gaagtaggaa gtatgcagac acagttgggc acaatcatgg atatctatcc
     8581 gactgttctg tctgtggcag gatgcgaagt tccccaaaac tacgtgatag acggattcga
     8641 tctgaaaaag caactgagcg gtaaggtgga caagaagcgt cccgagtctt tcctgatgca
     8701 cttccctcac gcacaccgcg gcagctactt caccacctat cgcatgggcg actggaaact
     8761 gatttattat tatcttcccg agactccgaa acaacccaaa gctttgcttt acaatctgaa
     8821 agatgatcca gaagaaagaa atgaactttc ctccgcacat ccggataaat gcagggagat
     8881 gattcaggaa atgtctgctc aattagagaa ggaaggagct ctttatccgg tggataaaca
     8941 aggaaatgag ttgaaacctt ttgtttactt ttgattggca ttgattttgg tttgcaagag
     9001 tattgatgtc ttatccgcaa attgttttaa atgtaattgc atagacattt cagtcaatat
     9061 atgaagttca gttgataata gttatgcttc atatatacag ctccttaggt tagcgttcta
     9121 aggagttgta taattcttgc atctcaaatt gctatactat atcctttaaa tttacttcta
     9181 gggtattggc tattttcaca agagtaccaa tagtgaaatt agttctccct ttctctattc
     9241 gaataacgtt gttgtactcc atttcaagtt tatctgcgaa ttcttggata gatagattct
     9301 tactttcccg taattttcta attttagtac ctatctcatt taaagtttcc tgtttatcaa
     9361 gcataatctc tgtcatatat gattgttttc aaaggaaagt atttatattt gcatattcgc
     9421 aatcatatat gattgtatgg tgagatataa taatgctaat ggaatattca gttgagtaat
     9481 aacaataaaa aaatgatgag atggatacac ttaatttgca ttcaaacttt gacaacctac
     9541 tatatatagg tagaagcgta ttaaataata cgagcagtca cattcaaaaa ttattcttta
     9601 aaaaagagat gtgtatatat gagtacttgt ataaggagga ggtaagtaaa ggcattgaaa
     9661 ttaaaataga tgatgttgtc ttagtttgtg ctttagaaca tgataaatgc aataagtcca
     9721 ttctttattt taatgacgta gcaaatatcg cacgttacat tcattactgt aacagtaatt
     9781 ttgaatataa agaagaactc aatgggtgga tcatgtcaga tagttatctt gctttatcta
     9841 tatctgagga tgattatgag aagcgatttg cgtttataca aactttacta tgaacttaac
     9901 tgagtcgttt tattatactt ttgctaatga gtaaaaagaa aatcccccgc cagctaacgc
     9961 cgacggggga tttatgctat taatcaaatc aagctcacgc ttagtctttc agtttagcga
    10021 tgatgaagtc gcggttcagg cgggcgatgt tgctgataga gatgttcttc ggacattcag
    10081 cctcgcaagc gcgggtgttg gtacagttac cgaatccgag ttcatccatc ttggacaaca
    10141 tagctttcgc acggcgcaga gcttccggtt taccttgcgg aagcaagttc aactggctga
    10201 cctttgccga aacgaacaac atggcagaac cattcttaca agcagctaca caagcaccgc
    10261 aaccgataca agaagcggca tccatagctt cgtcagcgat gggcttcggg atcaggatag
    10321 cgttggcatc ctgcggagca cctgtacgaa cgcttacata accaccggcc tgcatgatct
    10381 tgtcataagc agtacggtct accatcaagt ccttgatgac agggaaaccg gccgaacgcc
    10441 aaggctcaac agtgatggtg tcaccatcgt tgaaacgacg catgtaaatc tggcaagtag
    10501 tagcacctgt tgcaggaccg tgcggatgtc cgttgatgta aagagaacac ataccgcaaa
    10561 taccttcgcg gcagtcgtgg tcgaatacaa ccggttcttt tctttcgctg atcagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
    10681 aggtttcaaa agcgccttta gccttcgggc ctgcttgacg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc gtctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg ggtctgaacc ttgatagctt cgtataccag cggttctttg atcaatacag
    10861 gagccttttc atcgtcaccc tgatattccc agcaagctac gtagaagaag ttttcgtcat
    10921 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcgtcg taagcaacga gctcgcccat agtgatgaag tcatacagac
    11041 ggatagcctt gtcgagctca acgttcatac cttccttaga accggggata aacagattgg
    11101 tttcgaattc cttgcggact gctttcagtt cggcgatacc tttcttcagg ccttctgccg
    11161 tacgtcccat acctacgtat tcccacatga tgtgacccag tttcttgtgg atagaatcaa
    11221 ctgattcttt accctggatg ctcatgaact tgtcgatctt agcctgaact gccttttctg
    11281 cttcggcaaa ttccggaagg tcagtagaga aacgaggaac agtaatctga tctgccagat
    11341 agttctggat agtgtaaggc aatacgaagt aaccgtcggc cagaccttgc atcaatgcgg
    11401 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatggt agtctgcagt tcgtagtcta cccagatacc acccattgtg tagtggatag
    11521 ccggataaat catcatcgga ttataatatt tcacaccact gatttctttt gccagttcgc
    11581 ccggattaac gtcagtgatt tcttcataca tgtcgaagag gttaccataa cgctgaagca
    11641 ctacatcgat gcccaggcgg ttgatagctt cagagaaatc gaggaatacg gccagacctg
    11701 tgttgttcac accgaaacct gcgtcgcaac gttctttagc tgcacggctg gcaacgtcac
    11761 gcggaaccag gttaccgaat gccggataac ggcgttccag gtagtagtcg cggtcttctt
    11821 caggaatatc gcttcccttg atctcgcctt tctgcaattt gatagcgtct tctttcttct
    11881 tcggaaccca gatacggccg tcgttacgca gagattcgga catcagagtc agtttggact
    11941 gcttgtcacc gtgtaccggg atacaagtcg ggtgaatctg aacgtatgcg gggttagcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttgg
    12061 tagacaggaa gtaagcgtta ccgtaaccac cggtagcgat tactacggcg tgagcagcga
    12121 aacgttccag ttcgccggtg attaagttct tggcaatgat accgcgagca cgtccgtcga
    12181 tgattacaac gtcctgcatt tcataacggg tgaacagctt caccgtacct acgtttacct
    12241 gacggcttag tgcggagtaa gcacccagca acagctgctg accggtctgg cctttagcgt
    12301 agaacgtacg tgatacctgt gcaccaccga aagaacggtt gtccagtgta ccgccgtatt
    12361 cgcgtgcgaa aggaacacct tgtgccacgc attggtcgat gatagcgttg gatacttcgg
    12421 ccagacggta aacgttggct tcacgtgcac gatagtcacc accttttact gtatcgtaaa
    12481 acagacggta aacggagtca ccatcattct gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cggcgcggag agtcctgaat acagaagttg aatactctga
    12601 aacccatttc accgagggat gcagcagcag aagcacctgc cagacccgta cccacaacga
    12661 tgatatccaa acggcgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaag gagtgatttc
    12841 acgaagaata ccactactac gagtgcgaaa ccgagtacta caatcgtaga atagatgtta
    12901 gaaatacatt tccaacgatt gatccatacc ttgttgttcc atcccagtga ttgcatggag
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaatgag gtagagcact
    13021 acataaaccg gacaagagaa tgtctgctgg atgtgatatg caccgtttgc cgcataagcc
    13081 agcgtcagtg tatcagcgtg catgtccagg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccgagg cctacgataa cgataatgcc taacaccaac
    13201 atgttttgag aagcccactc tacagttttc ggtttgtcga ctactgcata gcgttcgcta
    13261 ccgcgcgctg tgcgattctg cattgtcagc cagaacgcgt agatgatgtg aataatgaaa
    13321 agagcagcca gtgctgcggt agctaccagc gcataccagt ttgctccaag gaattcacaa
    13381 atcatgttgt aaccatcagc cgagatgatt gcaactaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
    13501 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
    13561 cgttttacac ctcttac
//
