LOCUS       c00011_gnlPro..        16522 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICKNNHJK_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:07:15
            Original ID  :: gnl|Prokka|ICKNNHJK_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16522
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16522
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9840:13398](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9841..13398)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16522
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16522
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             182..1408
                     /locus_tag="ctg11_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1741..4494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDERWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4522..4854
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4817..6103)
                     /locus_tag="ctg11_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6576..7802
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7799..8629
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8657..9517
                     /locus_tag="ctg11_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9528..9716)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9841..13398)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_9"
                     /sec_met_domain="PFOR_II (E-value: 6.1e-19, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 8e-83, bitscore: 267.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEAEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13432..14637)
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRYPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14817..15971
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 gatatttaat actgcaaatg taaatgtgtc aaaagcaact aaactctcct ccttcctgaa
       61 ggaggggaat ttagttgctt ttgacacatc ttcttttctg tttcttattt cagtaaatgt
      121 cccccttccc tgtgttttga tttactactt aatctgttaa ttattagaat gataataaca
      181 gatgttcttt tttctaattg tccccctctt tcttgccttg ttttataagc cgattgccta
      241 tctttgcggc aggtttttaa ataataaatc aaaaagagaa aactacttta tgaaacacat
      301 ttcgaacttc ctcagatcaa aaagctggaa cgtatttttg tttttatatc ttgctcttcc
      361 tttgtttgcg caaaaggaat ataagatcga tcaggtatct gttgttaatg taggcgatgg
      421 cagactgttg tttcaggaac tgaaaacgga aaaagcattg aatggcgaac atcgcatcat
      481 agatggttat cattccgcct atgtgctggc atcttttaaa gatggttttt atgatggcgg
      541 atacaaagaa tatgtggaca atatattaat aacggaagga agttataaag aagggcggaa
      601 ggatggcctc ttcaagatta actccaagtt tgacggtaag ctgaaagaag aaaagtccta
      661 taaggaaggt aagctggacg gtacgagcaa aagttacttt actaccggaa aagtggaaag
      721 tgaaagaaac ttccggatgg ggaaagagca cgggaagcaa ctgtcgtacg aatctgacgg
      781 tactttgcgg aaagagcata attacaagga cgggaagcag gtaggcaaac agtatacttt
      841 tctgaaaggt acatatgatt tgtatgagac cgtttatttc aatgaagaag gtttgcagga
      901 cggtgaatat tcgtccgtgt ttacgtttgg ctcgccacgt atactgggta gttataagaa
      961 tggaaagaag aatggtcggt ggactacttt tgctgaaagc ggagatacgc tgatgattga
     1021 aacctatctg gatggaaaag aagatggact ccatgtctca tttgccaacg gaagtggggt
     1081 aaggcagaaa gaatattata tgaagaacga tcgtaaagac ggtttatacc gtgaatataa
     1141 tctggaaaat ggtgaattga gatatgaagc tacctatcag gccggcagat tgcatggcaa
     1201 ggaacgacgg ctgatagtga gcaaccgctt tgattattgg gaaacttcta cctatgtgaa
     1261 cggaaggcag aacggaccgt tcgaagctcg ttatgtaaag aatgaccagc ttcgtgaatg
     1321 tggggaatat aagaatggtc gccgtgtagg acgatggaaa cgctacacta ttgatggtaa
     1381 actggaaaag gaatgggatg aaaactaacc ggtagatgaa aggtcagagc ataaaaaaag
     1441 gagcaacgcc ttgctccaac ctttgttaac cttaaatcta atactatgaa aaacacagtg
     1501 caaaggtacg gacttctgtg aaatctgcaa attatccaag taaaacgcta tgttttataa
     1561 cattgattaa gtgtttgttt tacgctttat acttttgtta atactttccg atggtctgaa
     1621 agaggactgc tttccttctt tttagaataa taaatagctg aagttagaga actttacagt
     1681 attatttctt atttttgttc ttaattggat tacagaaaga actatgaaat gatgagatgg
     1741 atgaagacga tgagatatct gaagtggatg ctggtgctgt ttggtttaat cgggatgacg
     1801 gcttgccggc aggatacacc ccgttttcgt attggggtgg ctcaatgcag cgatgattca
     1861 tggcgacata agatgaatga tgagattctt cgggaagcga tgttttataa tggtgtttcg
     1921 gtggaaatcc gttcggcagg ggatgataac agtaagcagg cggaagatgt ccattatttt
     1981 atggacgaag gagtcgatct gctgattatt tccgctaacg aagctgctcc tatgactccg
     2041 attgtagaag aagcttatca gaaaggcatc cccgttattc ttgtagaccg gaagattctt
     2101 tcggataaat atactgccta tatcggagcc gataattatg aaattggtcg ttcggtagga
     2161 aactatattg cctccagtct gaaagggaag ggaaatatag tagaactgac aggattgagc
     2221 ggttcgactc ctgcaatgga acggcatcag ggatttatgg ctgccatcag taaattcccg
     2281 gatataaagc tgattgataa agcggatgct gcttgggaac gtggtccggc agagatagaa
     2341 atggatagta tgcttcggag gcatcctaag attgatgctg tgtatgccca taatgaccgt
     2401 atcgctccgg gtgcctatca ggcagcaaag atggcagggc gggagaagga aatgattttt
     2461 gtcggcatag atgccttgcc gggtaaggga aacggactgg aactggttct ggacagtgtg
     2521 ctggatgcca cctttatcta tccgaccaat ggtgataagg tactgcaact ggctatggat
     2581 attctggaga agaaacccta tcccaaagaa acggtgatga ataccgctgt tgtggaccgt
     2641 accaacgcac acgtcatgca gttgcagacc acacacattt ccgaactcga caaaaagatt
     2701 gaaacgctca acggacgtat cggtggctat ctctctcagg tagctacaca acaggtcgtt
     2761 ttatacggca gtctgattat ccttttattg gtagccggct tattattggt cgtttataaa
     2821 tcactccgct caaagaatcg cttgaataaa gaacttttta agcagaagca acaattggaa
     2881 gagcaacgtg acaaactgga agaacagcgt gaccaattga tacaactttc tcatcaactg
     2941 gaagaagcta ctcatgccaa gctggtattc ttcaccaata tttctcacga cttccgtact
     3001 ccgttgacat tggttgccga tccggtagaa catttgttgg cggacaagac actgagcgga
     3061 gatcagcacc ggatgctcat gctgattcag cggaatgtga acattcttct gcgtctggtc
     3121 aatcagattc tggatttccg taaatatgaa aacggcaaga tggaatatac tccggttacg
     3181 gtggatgtcc tttcttcttt cgaaggatgg aatgagtctt ttcaggcggc agcccgtaag
     3241 aagcatatcc atttttcttt tgatagtatg ccggatacgg attatcatac actggcagac
     3301 atggagaagc tggaacgtat ttatttcaat cttctgtcca atgcctttaa gtttacaccg
     3361 gaaaacggga aaatagccgt ccgtctgtct tcccttagta aagaggacga gcgatggata
     3421 cgtttcacgg tggcaaatac cggttccatg atttctgccg aacatattcg caatgtattc
     3481 gaccgtttct ataagatcga tatgcaccat accggttcgg gaatcggact ggcattggta
     3541 aaagccttcg tagaaatgca cggtggtatg atctccgtag agagcgatga gaaacagggc
     3601 acggtcttta ccgttgaact gcctgtacag tcttgtgagg ctgttgctgc cgaaccggat
     3661 accacccttg tttctgcgga ttcccgtaca acagatgttc tattggcgga agaggaagaa
     3721 ctggaaaaag gatatgactc ttccaaaccg tccgtactga ttattgatga taatgaggat
     3781 atccgttcgt atgtccatac gttgttgcat acagactata cggtgattga agcggcagac
     3841 ggctccgaag gaatccgtaa ggctatgaag tatgttccgg acctgatcat ttctgatgtg
     3901 atgatgccgg gcattgatgg cattgaatgt tgccgccggc tgaaaagtga gttacagacc
     3961 tgtcatattc cggttattct gctgacagcg tgttcactgg acgaacagcg tattcaggga
     4021 tatgacggtg gtgcggattc ttatatttca aagccgttca gttcacagct gttgctggca
     4081 cgtgtccgca atctgattga ttctcaccgt cgtctgaaac agttctttgg tgacgggcag
     4141 acattggcaa aagaagatgt ctgcgatatg gacaaggatt ttgtagaaag attcaagtca
     4201 ttgattgaag agaaaatggg agactccggt ttgaatgtgg aggacttggg caaagacatg
     4261 ggactaagcc gtgtgcagct ttaccgcaag attaaatcat tgactaacta ctctccgaat
     4321 gaattgctcc gtatcgcccg tttgaagaag gcagcttctt tgcttgcttc ttcggacatg
     4381 accgtagcgg agattggtta tgaagtcggt ttcagttcac cttcttattt cgccaagtgc
     4441 tataaagagc agtttggaga gagcccgaca gatttcctga aaaggaaagg atgatttcat
     4501 tgatatcgta aagagggata tatgaaagat tataaagtag ataaagagag cttttccgaa
     4561 tcctttcgga aggaagtgta cgaagtcgta tcccagatac ctgtgggaaa agtatctact
     4621 tatggaggta ttgctttgct gttgggggca ccccaatgct cgcggatggt gggacgtgca
     4681 ttgaaagaag tgccggatga attatccatt ccctgccata gagttgtaaa ttccaccgga
     4741 aggctggtgc ccggttgggt ggaacaaaaa caactcttgc tggcagaaga agtttctttc
     4801 aaagctaacg gatgcgttaa tctgaaagaa catttgtggc acgtggatga atgaaggatg
     4861 caaggaaggt aagccatatc atccgtatcc atacaataaa gaaaacccat acatgaagcc
     4921 ataaggtcct ggtaatgaaa tctctgatgg gtacagggac gaatatgtcg ataggaacga
     4981 tacataacag cacaaaacag caccaaaata gaatcttgtc tgttgcggta cgtgttggtc
     5041 tgctccaata ccagagcatg aaacctgcca atgcgataat ataggtatgc ttctcggcgg
     5101 agtcactcag taatactacc cagcccatga gaatgcccaa agcctgggca cggaaggcaa
     5161 aagacgacca tttgcggaaa ttccccaaaa agagcagagt cagcaagccg agcattccta
     5221 tctgaagtgc acggaagtgt ggcaatgtcc atgctgcaat ggggcgggca tagaaaaatg
     5281 aatcataagc tccggcggac tgatgaacag caagactatg gcaccattct tcataatagg
     5341 ggagcaaatc tgcaggagct atttttatta acggtaatgc aagcaataca atgcccattg
     5401 taacggcata gccaaagtta cgccatacgt gaggatagca cagcaacaat gccagttcga
     5461 aaattccata tactttggta catcccgaaa tcatgattaa cagaacagcc agaaatccac
     5521 ggtctttttc caataacgta taggcgaata agaataaata ggctaccgtt atgttatact
     5581 gaaatgaaag taaactttgt cctaaaatca gtaacagaaa aaggaacata cggcatttct
     5641 gctgctgggt gaattgttgg ggcagcgtga agatcgccat aaagaacagc gaataattga
     5701 atagattcca cgcgaaaggt cccagccatg caggcagata cgcaaacgga gcgaacaata
     5761 ccgtgaaaac tggagaataa aggaagtagc gtccgtgagc ttctacaaat tcagttgtgt
     5821 atgggctgat gccttgccag aagaattgag tagcgtccga gaagaccata aagttttgat
     5881 gccgtcctcg tataaattcg agcagagtca ctataaaagc gagcaggaaa cctatcatgt
     5941 agagattccg ccggctatag aaaaacggca ttttggggtt ctttttacta aggaactgta
     6001 cttggctttt gtcgtctagt gtggcagtac ctgtttgttt ttcttttgtt gtgtaatgac
     6061 aattatcctt ccccaggaaa attgtaatag ccctgttgaa catataaatc tagtttagtt
     6121 attgacgcca aatatacggt gtttaagtga aatattcaaa cttattttat atttatctgc
     6181 cggtttgttc tattttgctg agtgataggg gaatattacc cggaaacttt ccatatcatt
     6241 acaaataaag ccctctgtat gccccggatt ttgaatataa tttgtatgtt taatccgttt
     6301 tttgtatctt tgtgccagca agatactgga acaggctgtt tttatacata aaaatgctat
     6361 tttttgctat tcgttgaaag gattatctta tcaaattcta ttcctttttt aattactcag
     6421 tctgtcaata atcattttat taattatttc gggattcatt gttatttgtc ccttatttaa
     6481 atcagaactt tatacgatat aaagaaagat tcctgttatc gtttgttctt gtcttgctgt
     6541 gtatattatt ttaataacct aaaccatttt attgtatgag taaaatagaa attaaagatc
     6601 tctatctggt ttttggcaat gagaagcaga aggctttgaa gatgttgaaa gaaggtaaaa
     6661 caaaaagtga aatattgaaa gcgaccggat gtacagttgc ggtgaaagat gcgaatcttt
     6721 ccattaatga aggcgaaata ttcgtcatta tggggctgtc cggtagtgga aagtccactt
     6781 tactccgctg catcaaccgt ttgatacgcc ctacttccgg agaagtgatt atcaatggaa
     6841 cagacatagc caaagtgtcg gataaggaac tgttgcagat tcgccggaaa gaactggcta
     6901 tggtctttca gaacttcggt ctgcttcctc accgttctgt cttgcataat atagctttcg
     6961 ggctcgaact acagggagta aaaaagggag aacgggagca gaaagcgatg gaaagtatgc
     7021 aactggtggg gctgaaaggc tacgagaatc agatggtaag tgaactgtcg ggtgggatgc
     7081 agcagcgtgt cgggctggcg cgggctttgg ccaataatcc cgaagtcctg ttgatggatg
     7141 aggccttctc ggcactcgat cctttgatcc gtgtgcagat gcaggatgaa ctgctgactt
     7201 tgcagtcgaa gatgaaaaaa acgattgtct ttattactca cgacctgagt gaagcgatta
     7261 aattgggtga ccggattgct atcatgaagg atggagaaat tgtacaaatc ggtacatcgg
     7321 aagaaatcct gaccgaacct gccaacgctt atgtagaacg atttgtggag aatgtagatc
     7381 gaagcaagat tataacagct tcctctgtta tggtagataa acccatagtg gcacgtttga
     7441 agaaagaagg cccggaggtg ctgatccgta agatgcgcga acggaatctg accgttcttc
     7501 cggtagtcga ttccaataat ctgttagtag gagaggtgcg gttgaatgac ttgctgaaac
     7561 tacgaaaaga gcaaatccgc tccatcgagt ccgtagtaag gcatgaagtt cattcagtgc
     7621 tgggtgatac ggtgctggaa gatattcttc cgttgatgac aaaaacgaac tcgccaatct
     7681 gggtcgtaaa tgagaatcgg gagtttgaag gcgtagtgcc actttcctca ttgatcatcg
     7741 aagtaacggg aaaagataaa gaagaaatta atgaaatcat tcaaaacgca atagaattat
     7801 gataaatatc ggacaatata tagagactgc cattaattgg ctcacagaac attttgcttc
     7861 cttttttgat gctctcagca tggggatcgg aggattcata gacggttttc agcacgtact
     7921 gtttggaata cctttttata tcacaattgc agtgctggct gcgctcgcct ggtttaagtc
     7981 gggtaagggg acagccgtat ttaccctctt gggtttattg cttatttacg gcatgggctt
     8041 ttgggaagaa acgatgcaga cattggcatt ggtactttct tccacttgtc tggcattgct
     8101 tttaggcgtt ccgttgggaa tctggactgc caacagtgat cgttgtaaca agataatgcg
     8161 ccctgtcctc gactttatgc agacaatgcc tgcctttgtc tatctgattc ctgccgttct
     8221 attcttcgga ttgggaactg tgccgggagc ttttgccacc atcatctttg caatgcctcc
     8281 tgtggttcgt ctgaccggtc tgggcattcg tcaggttcct aaaaacgtag tagaagcctc
     8341 ccgctctttt ggagctactc cctggcagct tctttataag gtgcaattgc ctttggcgtt
     8401 gcctactatt ctgacgggaa tcaaccagac gatcatgatg tcactttcga tggtagtgat
     8461 tgccgccatg atttctgccg gaggattggg agaaatcgtg ctgaaaggta tcacccaaat
     8521 gaaaatcgga ctcggatttg aaggcggtat cgcagtcgtg atattggcga tcgtgctgga
     8581 ccgcatcact cagggtatgg cagataacag aaaaagtaaa aagaaataag aatcacacca
     8641 aagaaaggaa taatcaatga ataagataaa aatgattgcg gcaatgttta ttgccggcat
     8701 actcttaacc ttcgtttcct gcggagacaa cggaaagagt aagaagataa gtatcgctta
     8761 tgccaactgg tcggaaggta ttgcaatgac aaaccttgcc aaagcgattt ttgaagatca
     8821 ggggtacgat gtaaagttgc tgaatgccga ccttgcacct atatttacct ctatctcccg
     8881 taagaaagca gacgtattta tggatgtctg gatgcctgtc actatggaag attatatgaa
     8941 acaatacggg gataaactcg aagttatcgg ggatatttat gatggtgccc gtatcgggct
     9001 ggtggttccg gattacgtta cgatcaactc aatcgaagaa ctgaacgcgg aaaaggaacg
     9061 tttctccggt cagattgtcg gtattgatgc cggagccggt attatgaaag ctaccgatca
     9121 ggccatcaaa gactatggat tggattataa actgatgact tcgagcggac ctgccatgac
     9181 tgcttcccta aagaaagcga ttgataagaa agactggatt gtcgtgacgg gatggacgcc
     9241 tcactggatg ttcgaccgtt tcaagctgaa agttcttcag gacccgaagc tgatatatgg
     9301 aaatacggaa tccattcata ccatagcatg gaaaggtttt agcgagaaag acccttttgc
     9361 tgccgaactt ttgggcaaca ttcgtctgac agatgcggaa atcagctcct taatgactgc
     9421 tctggaagag gcgcagacaa cggaaagaca ggctgcccgt caatggatgg aagaacatca
     9481 ggaactggtg aacagttgga ttcctgagaa agattgatat gcaaacacta cttcaaccat
     9541 cccgccattc tttctttacc atagaagtag tagaaaagta gtcccagcca gctggtaaga
     9601 acgattaata caatcgctat aagtcttttc tctacagccg catttatatt ccaaatctct
     9661 atggcagctc tgaaagtcag tatcaaaccg ataatccaaa taacaaatcc gatcatatct
     9721 ttagagtttt aatgaatatc ttcgtgagaa gtaatcgtta cttctaagat ataaacaaaa
     9781 aaggcaggaa tctgtttcca ggattcctgc cttttattat gtacaaagta tttctactta
     9841 ttattcagct gtatcagctc cccagttttc tctggcaaga cgtttgtagc tgttgtaacg
     9901 ccatttagcg ttttcttcag cagctttaaa cagttcttca gcttcagcag gatattgttt
     9961 cattacagaa gcgtaacgaa cttcaccctt caagaaacct tggaaatctt cccagttcgg
    10021 ttctttgcta tccaactgga acggattctt accttctgct tccaaagccg ggttgtaacg
    10081 ccacaagtgc cagtaaccgc acttaacagc cttttcttct tcttcctggc tcttacccat
    10141 accggctttc agaccgtggt tgatacatgg agcgtaagcg atgatcagtg atggtcccgg
    10201 atatgcttca gcttcacgga tagctttcag agtctgagcc tggtcagcac ccatagcaat
    10261 ctgagcaaca tatacataac cgtaagtagt agccatcaga ccgaggtctt tcttacgtac
    10321 gcgcttacca gcagcagcga acttagcgat agcacctacc ggagtagctt tagaagactg
    10381 accacctgtg ttagagtaaa cttcagtatc cagaacgagg atgttaacgt ccttaccgga
    10441 agcgattaca tggtcaagac caccgtaacc gatatcataa gaagcaccgt caccaccgat
    10501 gatccattgg ctgcgtttaa caagatattg ttgcagatca gcgatttgct tgcagtggtt
    10561 gcatttatct ttagcagctt ctaccatcgg aatgatcttt tcggccagtt ccttagtctt
    10621 ttctgcatcc agcatattgt tgatccattc agcaaatact tctttgtatt cagccgggca
    10681 gcaatcagaa gcgatagctt cgttcattac tttcaccaga cgggcacgca tcttttcgtt
    10741 agccagttcc atacccagac caaattcaca gaagtcttcg aacaaggagt tagcccatgc
    10801 aggaccgtga cccttttcgt tcatagtgta cggagtagaa ggaactgaac cggagtagat
    10861 agaagaacat cctgtagcgt tagcaaccat ttcacggtca ccgaacaact gagaaatcag
    10921 tttcacgtac ggagtttcac cacaaccgga gcaagcgcct gagaactcaa acaacggagt
    10981 tgcgaactga gagttcttca cgttagcctt gatgtctacc aggtgttgtt tgctcttcac
    11041 gttttcagcg cagtaagtcc agttatcagc ttcggccaac tggctttcaa ggtgtttcat
    11101 ggtcaatgcc ttaccaccct tcttcggatt acccggacag atgtcggcac agttaccgca
    11161 acccagacag tcgagaacgt ctacctgaat acggaatgtc ataccatcga atgctttacc
    11221 tacagctttc agttgctcga acttagcacc cttctgctct tcagcatcga gtacgaacgg
    11281 acggatagaa gcgtgaggac aaacgtaagc acacttgtta cactgaatac agttttcagc
    11341 attccattcg ggaacgaatg cagctacacc acgtttttcg tatttggaag taccttgata
    11401 ccaagtaccg tcttcgatac ccttgaatgc agataccggc agcaagtcac cgtcctgtgc
    11461 attgatcgga cgaactactt cgttgatgaa agcaggatca ttgttttctg cttttgcatc
    11521 atccggcagg ttagcccaag caggatcgac agtcagagtc ttgtattcac caccgcggtc
    11581 tacagcagcg tagttcttgt taacaacgtc ttcacccttc ttgccgtaag acttaacgat
    11641 gaatttcttc atctgttcaa cagcttgatc tacagggatt acgcctgtga tacggaagaa
    11701 tgcagactga aggattgtat tggtacggtt gcccaaacca atttccattg caatctgagt
    11761 tgcgttgata tagtatacag agatgttgtt ctgtgcaaag tatttcttca ccttgttagg
    11821 caggttctta gccagttctt cgccttccca gatggtattc agcaagaaag aaccgttctt
    11881 acgcaaacca cgtgttacgt cgtacatgtg caggtaagcc tgaacgtgac aagcaacgaa
    11941 gttcggagta tttaccaagt aagtagaacg gataggagta tcaccgaaac gcaagtgaga
    12001 acaagtgaaa ccacccgact tcttggagtc ataagagaag taagcctgac agtgtttgtc
    12061 ggtgttgtca ccgataatct taacagagtt cttgttggca cctaccgtac cgtcagcacc
    12121 caaaccgtag aatttagctt cgaacatacc ttcgccgccc aaagcgattt cttctttctg
    12181 agggagagaa gtgaaagtaa cgtcgtctac gataccgata gtgaagtggt tcttcggcat
    12241 cggcatagcc aggttttcga atactgaaag gatctgtgca ggagtagtgt ccttagaacc
    12301 cagaccgtag cgaccgccaa cgataaccgg agcgttttct gcaccgtaga agcagtcttt
    12361 aacgtcaaga tacaaaggct cgccgttagc acccggttct ttagtacggt caagaactgc
    12421 aatagtctta gcagtcttag gtacagcagc caggaagtgt ttagcagaga acggacgata
    12481 caagtgtacg gcaaccatac ccactttttc gccgtttgct accaagtagt cgatagcttc
    12541 gcgtgcagct tccgttacag aacccatagc gataattacg cgttctgcat cttctgctcc
    12601 gtagtaatca aacaaaccgt atttgcgacc tgtaatctta gaaatttcat tcatgtattc
    12661 ttctacgata gcgggaactg cttcatagta gttgttgcat gattcacgat gttggaagaa
    12721 gtggtcgggg ttttcagcca taccacgggc taccggattc atcggattca gtgcgcgggc
    12781 acggaattca gccaaagctt cctgatcaat cagcggagca agatcttcgt tttccaacat
    12841 ttcgatcttc tggatttcgt gagaagtacg gaaaccatcg aagaagttca tgaacggaac
    12901 gcgtgatttg atagtagcca gatgagcaac acctgccaaa tccataactt cctgtacaga
    12961 accttctgcc aacatagcga agccggtttg acgagctgac attacgtcct gatggtcacc
    13021 gaagatacac aatgcgtgag aagccagtgt acgagcagaa acgtggaata cacaaggcaa
    13081 gaattcaccg gcaatcttgt acatgttagg gatcatcaaa agaagaccct gagaagcagt
    13141 gtaagtagta gtcaatgcac cagcctgaag agaaccgtga actgcaccgg cagcaccacc
    13201 ttcagattgc atttcctgta ccaatactgt ttcgccgaag atgttcttac gtcctgcggc
    13261 agcccattcg tctacgtact cagccatagt cgaagaagga gtgatcggat agatagctgc
    13321 tacttcagag aacatatacg agatatgtgc tgcagcttgg ttaccgtcac aagtgatgaa
    13381 tttcttctgt ttagtcataa ctaaattaaa tatttaagta aataaatctt tttagtataa
    13441 gaatccgaac atccaaagag gtatttggtt gccgcggcct atctcagcct tttgcaacgc
    13501 atacgtcacg tccgggttat tctttatttt tgtaccttcc gcacaaattt tgaacggcat
    13561 cacttcgtct accatgaaag agacgttttt atctccttta tgtaccttat ggtctttcca
    13621 taaagtgtta acgaagaacg tgtcgagtac atcctgttct tccactttca ccggataaat
    13681 ggagtacatc aggttagagt tgtgcatcat aatctttgac ggtttctttg ggaattcttc
    13741 tcctttcggg taaaccagat taatcagacg cgcgtctgcc agatacttga tatagttcat
    13801 taccgtagcg cgggatgtct gtacgtcact tgccagttgg ctcacgttcg gagctttcgg
    13861 tccgtccaca gccaacaaat atagtaattt ttttatcttt gaaagatatt tcagctcaat
    13921 ttgtttgata agcaggatat ctacttccac catcatgttc attgtcttca gcagattctc
    13981 cgaaaagtta cgcttttcga ggaagaaggg gtagaatcca tgatgcaggt aatcctgaaa
    14041 gtaatccagc ggacgtactt tggaaagcac tcctttggca atctgttcgt gtgtactgag
    14101 aatctcttcg agactgtacg cccggaattt catacctgtt tgcaggttca gaaattcgcg
    14161 gaaagagaat ccgcgaagat tatagctttt cgcaatatca cgcaattcga ggttttcttc
    14221 tttcagccgc atcacggacg aaccggtgaa tacgattttc aggttcggat aacggtcgta
    14281 gcacatacgg agttctttgc tccattcggg atgcttaaac acttggtcga tcagcagaac
    14341 ttttccacca cgtttctgaa actcgttggc aaagtctacg atgctatgcc ccgagaaata
    14401 gaaattgttc atgttgatga acagacagga acggtcggtt ccgaatttct ctttggcgta
    14461 ttggagaagg aaagtggttt ttcctacgcc acgtgtccct ttgataccaa tcaggcggtc
    14521 gctccagtcg atctcgtcca taagatcgcg gcgaacgggg gcattggtgt gctcaacgag
    14581 gtaggcgtgt gtgcgataga atgattccat ttcgtttctt tgtttttcgg ctggcaaata
    14641 tagtgctttt tttaggattt gcaaagtaga gatagcaaaa atgtgcttta atttataagt
    14701 ttctctttat tgtgtaagtt cctgattatt tcctgtatat atttgcagaa taatgtgttg
    14761 aatccatctt tgacatgacg aaaagacctg tttatatatt caatccggag catgatatgg
    14821 cgttggcaag cggtgagacg aactatatgg cgccggcttc cgcccgacag atggcgagtg
    14881 acctggcgtt gcttcctatg tggtatgccg aagcgggaag tgcggtgctt gcaccgtctg
    14941 cttataatgc ggacttcctg aaaacaaaga gtgaactttt gggcatggat gtggccttgt
    15001 tgacggaacc ggaagtggct gacggtaaag accggaagtt ctctccgtgg ggttgggacc
    15061 ctgctttgcg gaagcgtttg atgacattgg gggcaggtca gacggagctg ccttctgcgg
    15121 attatatgaa tattctgaga gagcattcgc atcgtctgca ggcggtaaag ttgttgcctg
    15181 ggttgcggtt gaatgaatac ttctgtggag aatcttttta tttgagtact ttggcggagt
    15241 gcagtgcgtt cgtcgaaggg cgggaagcgt gcttgttaaa agctccgctt tccggaagcg
    15301 ggaaaggatt gaattggtgt aaaggcatat ttactacttt tatttccggt tggtgtgccc
    15361 gtgtcgctgc ttctcagggt ggggtggtag gcgaacctat atataataag gtggaagatt
    15421 tcgctatgga gttttatgct gacgggagag gaagggttgt ttttgccgga tattcggtct
    15481 tccacacggg tgggagtggg atgtatgcag ggaatgactt gctgtctgac gagaagattc
    15541 tgcagaaact atcggcttat gtgccacaag aagaatttat caggctgcgg actcgtttgg
    15601 aagaagaatt gtcagctttg ttcggtggct tttatcatgg atacttggga gtggatatga
    15661 tgatttgtca ttttccggat gaagcgcctg tttaccggat tcatccttgt gtcgaaatta
    15721 atctgcgaat gaatatgggg gtggtggcat ggctcttgac ggatcgttat ttggctgcgg
    15781 atgcggaagg agtttttcgg attgattatt atcctttagc cggtcaggct ttggaggaac
    15841 atcggcagat gtcggcttcg ttccctttgt ccgtagagaa taatcgggtg tgtgccggat
    15901 atttgccgtt agtaccggtg acgcctcaaa gccggtatcg tgcgtttctt ttgcttactc
    15961 tcccccagtg aaaaagatag tgcttttgct ctcatgctct aacagttcgt ctgtatccct
    16021 ttattcatcg atgttttagc tgttagagat ccagtggtag cagagtgaga gcaaggactt
    16081 gctctcactc tgcatcgtcc tgataaatac cgtttttact gtgttattct ttgatttaca
    16141 ggatgttaat atctgatatc tcaactgtta acgtttgatt tctcagatat taataattga
    16201 gaaatcaagt attaaggact gataatttat gtattattga ctgatatatg atttaatgtt
    16261 ttcagagaga gcagtactat tgaagtagct gatgcgttca atgtgattgg aacatgcggt
    16321 taagtcaatc aaatcaacag tagtttcaga tagtttcgag cgtttggaac taaagtttca
    16381 agcgtatgaa actctagttt ctcaccgatg aaactacagt ttcacaccga tgaaactctg
    16441 gtttcaagca atggaaactc tttgaagatt gtacttccct aataatggtt gacttgttta
    16501 tctctaatag ctgctatgtg tt
//
