LOCUS       c00146_gnlPro..         9359 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JPPFOEJA_146.
ACCESSION   c00146_gnlPro..
VERSION     c00146_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:21:16
            Original ID  :: gnl|Prokka|JPPFOEJA_146
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9359
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9359
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3086:7944]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3087..7944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..9359
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9359
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             110..2032
                     /locus_tag="ctg146_1"
                     /transl_table=11
                     /translation="MGISSPLVDLQHQYDLLQKEYEYEKETYRQQSERTGLRKRVAQGL
                     CWYPVTPGRSYYNSLNQLVIEIERTENREIEHNFEYGRPVCFFTADISGKFKYLDFSAT
                     ISYVQEDRMVVVLPTPSALMDIQGKSNDLGVQLYFDETSYKTMFSALSDVMRAKNNQLS
                     HLRDVLLGQEKPGQRELFPIRFPWLNRSQEEAVNKVLGAKQVSIVHGPPGTGKTTTLVE
                     AIYETLHRENQVIVCAQSNTAVDCISEKLVDRGINVLRIGNPTRINDKMLSFTYERRFE
                     SHPDYPELWSIRKAIRDIQSNMRKKSREERDTIRNRLSRLKFRATELEVKIDTELFDEA
                     RVVACTLVGSANRVMMNRHFTTLFIDEAAQALEAACWIAIGKADRVILAGDHHQLPPTI
                     KCIEAEREGLGRTLMQKIAHTKPETVSLLKIQYRMHEDIMRFSSQWFYHNELESAPEVS
                     GRGILRLDTPIVWFDTSECDFTENTREETMSRVNRQEAELLVEQLRSYIQKISKERVLE
                     ENIDFGLISPYKAQVQYIRKLIKQDAFFKPLRRLITVHTVDGFQGQERDVILISLVRAN
                     EDGKIGFLNDLRRMNVAITRARMKLMILGDASTLTRHAFYKELYNYISQRGKIITINTK
                     QEHEL"
     CDS             2022..2828
                     /locus_tag="ctg146_2"
                     /transl_table=11
                     /translation="MNYKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGR
                     PTYGIVPLAEELNIKQYGGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKEAG
                     LAILSYNGKYILSEHPENKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPEMLV
                     PLEEKLRQELGKRINVYRSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFN
                     DVSMIHFAGLGVAMANAQPPVKANADRITQYTNDEDGVARFIQELL"
     CDS             3087..4319
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_3"
                     /sec_met_domain="HBT (E-value: 1.1e-17, bitscore: 53.4,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGR
                     PTNGVQPLAEALELNHYGGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENG
                     FAIFTYHKDYILTDSPENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNL
                     VGLENHWKKRLDGVLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGV
                     ADVSMLQLAGTGVAMGNARDSVKACADFTTLSNNMDGVAVAIEKAILATIKPTEVPLDQ
                     LNARAKHALMGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAETVAGLGS
                     MILAKPDEMVVGMQVSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTSTDKLVSS
                     VRVINSILKKK"
     CDS             4316..5413
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg146_4"
                     /sec_met_domain="Chorismate_bind (E-value: 9.2e-55,
                     bitscore: 175.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLY
                     DIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIPSESDWDFSREKNEFPSNEIEIPSE
                     SEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRSYVY
                     LCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVAS
                     YIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGL
                     PKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGGGLLA
                     ASQLEDEWQETEDKLDTMRRIVGNL"
     CDS             5428..7116
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.7e-08, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFFN
                     CHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISADR
                     PAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHGKGP
                     VHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIAGQMS
                     LIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVPELVIT
                     YGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDAFEFLEKIAYMLEN
                     RQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRYAQLYTVP
                     ETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNGNLHNNLRI
                     LLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVHNAEELAAAM
                     SAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     CDS             7120..7944
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_6"
                     /sec_met_domain="ECH_1 (E-value: 2.1e-82, bitscore: 265.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTE
                     MSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQI
                     RSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP"
     CDS             7982..9040
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg146_7"
                     /sec_met_domain="MR_MLE_C (E-value: 3.5e-30, bitscore:
                     94.3, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKERFYKTEVVPRCLTFKQPAGTSRGVYTTRKLWEVRIRKEDEP
                     SVIGIGECAPLPDLSCYYGVDYEITLSKACLDLEHEGYVDTESLRHYPSILFGLETAMR
                     HYEQGGWRHYDTPFSRGQAGIPINGLIWMGDYKYMLEQVEEKMKEGFRCVKLKIGAIDF
                     DRELSLLKHIRAHFSAKEIELRVDANGAFTPSEAMDKLKRLAEMDLHSIEQPIRAGQLE
                     EMAHLAAESPLPIALDEELIGCNAPDEKRRLLETIHPQYIILKPSLHGGIAGCTEWVHL
                     AETILGSTPERPKWWVTSALESQIGLNAIAQWCATLGNPLPQGLGTGEIFKDDKHRLIQ
                     RKGDTIWFTNDL"
     CDS             9044..9358
                     /locus_tag="ctg146_8"
                     /transl_table=11
                     /translation="MPIQEDLQAFLAEWHDPSPFLEVQTSGSTGTPKRMRVRKDRMLNS
                     ARLTCDYLGLKKGDKALLCMPLRYIAGKMMVVRSLYAGLDLEVREPSGHPLADWGDTPL
                     R"
ORIGIN
        1 tacttaccgc aacttgggta cggaacgata attttagtac ttttgtcgcc tacttcggga
       61 cctagaacgc ccgggctgta tttatccgat taattgaatt gataaaggaa tgggaatttc
      121 atcgccgctt gtagatttgc aacatcaata tgatctcctg cagaaagaat atgaatatga
      181 gaaggaaaca taccgacagc aatccgagcg tacgggtttg cgaaaacgag tggcgcaggg
      241 cctctgttgg tatccggtca ctccgggacg cagttattat aactccttaa accaattggt
      301 gatcgagatc gaaagaacag aaaaccggga gatcgagcat aattttgagt acgggcgccc
      361 ggtttgcttc tttacggcag atatcagtgg taaatttaag tatctggatt tctccgccac
      421 gatcagctac gtgcaagagg accggatggt ggtagttctc cccactcctt ccgccttgat
      481 ggatatacaa ggaaaaagca atgatctcgg cgtgcaactc tacttcgacg agaccagcta
      541 taaaacgatg ttttccgctc tctcggacgt gatgcgggca aaaaacaacc aactctctca
      601 tctaagggac gtattgctgg gacaggaaaa accgggacag cgggaattat tcccgatccg
      661 cttcccttgg ttgaaccgtt ctcaggaaga agccgtaaat aaggtattgg gagcgaaaca
      721 agtatctatc gtacacggcc ctcccggaac tgggaaaaca accaccttgg tggaagccat
      781 ttacgagacc cttcaccggg agaatcaagt gatcgtttgc gcccaaagta ataccgccgt
      841 agactgcatc tcggagaaac tggtagatag aggcattaac gtcctgcgca tcgggaaccc
      901 cactcgtatc aatgacaaga tgctctcttt cacatatgaa cgccgtttcg aatcgcatcc
      961 ggattatccc gaattatgga gcatccggaa agcgatacgg gatatacaat ccaatatgcg
     1021 aaagaaaagc cgggaggaac gggatacgat ccgaaaccgc ctctcccgtt tgaaattccg
     1081 ggcgaccgaa ctggaagtca agatcgatac agagctgttc gacgaggctc gtgtcgttgc
     1141 ttgcaccttg gttggctccg caaaccgggt catgatgaac cggcacttca cgaccttgtt
     1201 tatcgatgag gccgcccaag ccttggaagc tgcttgctgg atagcgatcg gcaaggcgga
     1261 ccgggtcata ctagcgggcg atcatcacca attgccccct actattaaat gtatagaagc
     1321 ggaacgagaa ggcttaggac gtaccttgat gcaaaagata gcccacacga aaccggaaac
     1381 agtctctctc ctgaagatcc aatatcgtat gcacgaggat atcatgcgct tctcctccca
     1441 atggttctat cataacgaac tcgaatccgc tcccgaggta agtgggcgag gaatcttgcg
     1501 actggacact cccatcgtat ggttcgatac gtccgagtgc gatttcacgg aaaatacgag
     1561 agaggagacc atgagccgtg tcaacaggca agaggcggaa ttgctcgtgg aacaattacg
     1621 ctcctatata cagaaaatat ccaaggagag agtgctggag gagaatatcg acttcggatt
     1681 gatctcccct tataaggcgc aggtacaata catccgtaaa ttaatcaaac aggacgcttt
     1741 cttcaagcct ttacgcagac tgattaccgt acataccgta gacggtttcc aagggcaaga
     1801 acgcgatgtc atcttgatca gtttggtaag ggccaacgag gatggaaaga taggcttctt
     1861 gaacgacttg cggcgcatga acgtagcgat cacccgtgcc cgtatgaaac tgatgatctt
     1921 gggagacgct tccaccctta cccggcacgc attttataaa gaactctata attatatctc
     1981 ccaaagaggt aaaataatca cgatcaacac gaaacaagag catgaactat aaattattgg
     2041 tactggattt agacggtaca ctgacaaaca gtaaaaaaga gatcaccccg tttacgaggg
     2101 aaacccttct gcaagcgcag gaaaaaggat tgcatctggt cttagcctcc ggccggccca
     2161 cctacggtat cgtgccttta gccgaggaac tgaacataaa gcaatatggt ggttttatcc
     2221 tttccttcaa cggcggtaag gtgatcgact tgatgacaga caaagtactt ttcgaacagg
     2281 ctttgccacc cgatatcgta cctgttttat acaaccgctc caaagaagcg ggactggcta
     2341 tcctttccta caacggtaaa tatatcttaa gcgagcaccc ggaaaataaa tacgtacaat
     2401 acgaatcatt cctaacaaag atgaagatca aggctaccga cgatttcctg cgggatttac
     2461 atcaacctgc cgataaatgc ttggtggtag gcgaaccgga gatgttggta ccgttggaag
     2521 agaagctccg ccaagaatta gggaaacgta tcaacgtata tcgttccgag gcattctatc
     2581 tggagcttgt ccccaaaggt atcgacaaag ccgcctcatt atcccgctta ctagagcgaa
     2641 cccggataaa acaggaggaa gtgatcgcta tcggcgatgg tttcaacgat gtatccatga
     2701 tccatttcgc cggattggga gtcgctatgg ccaacgccca gccccctgtc aaggccaatg
     2761 ccgaccgcat cacccaatac acgaacgatg aggatggagt ggctcgtttc atccaagaat
     2821 tgctttgaaa aaaacacgta cgtattttcc gagaaacacg tacatgtttt cgcgagaaca
     2881 cgtacgtgtt ttttcagaga catttacacc agtatcgaca caggccaatg cctatatcgg
     2941 cataagcctg tacgtatatc gccgcaaggc tacaccgata taggcgtgag cttgcgccga
     3001 tatacgtaaa ttcctttcat ggaaatgtct tctaactatc aactatttta tgtacatttg
     3061 tattctaaac cataaaataa gacgccatga agtacaaatt attagtctta gacgtagatg
     3121 ggacgttgct taacgacaag aaagagataa ctccccggac ccatgccgcc ctgttaaagg
     3181 ctcagcagat gggagttcat gttgtattgg catccggccg acccaccaac ggggttcaac
     3241 ccttggcgga ggctcttgaa ttgaatcatt acggtggttt catattatct tataacggag
     3301 gtcagatcat caatgcccag accggagaat tgatgttcga gaaacgaatc gatccggcca
     3361 tgattcctta tttgaaccgg aaggcgaagg aaaacggttt tgctatcttc acgtatcaca
     3421 aggactatat cctgaccgat agcccggaaa acaagcatgt ccaagaggag gccgaactca
     3481 ataagatgcg catcatcggt gtggagaatt tcccggaagc ggtggatttc gcaccctgta
     3541 agtgtattct taccagcgat gacgagaaca atctagtggg tctcgaaaat cattggaaga
     3601 aacgtctgga cggggtattg gaagctttcc gctccgagga ctatttcttg gaggtagctc
     3661 ctcatttcat caataaggga aatacgttgg cggtattgat ggagatgctg aatatcacga
     3721 ccgaagaggt tgtcgctatt ggtgatggcg tagccgacgt atccatgctt caattagccg
     3781 gtaccggcgt ggcgatgggt aacgcacgcg actccgtaaa ggcttgcgcc gatttcacga
     3841 ccttatctaa taatatggat ggtgtggcgg tagcgatcga gaaagcgatc cttgccacga
     3901 tcaaacccac ggaggttccg ttagatcaac taaacgcacg ggccaaacat gccttaatgg
     3961 gtaatctagg cattcaatat acctatgcgt cggaggatcg tgtggaagcg accatgcctg
     4021 tagacgaacg gacccgccag cctttcggta tcttgcacgg aggcgctacg ctggctttgg
     4081 cggagaccgt ggccggacta ggttccatga ttctggcgaa accggacgag atggtagtcg
     4141 gcatgcaagt tagcggcagc catatgtcgt ccgcccacga gggagacacg gtacgtgccg
     4201 tcgggacgat tatccacaaa ggccgttcat cccatgtgtg gaacgtagac atattcacct
     4261 ctaccgacaa actggtttcc tcggtacggg taatcaatag catactaaag aagaaatgat
     4321 tccaagagat tcttacgaaa taatagacac gttgatcaag caaggccgga gtttcgctat
     4381 ttggcgtatt cccggtgagg ataggctcca tttcaggatg caaagcgccg gctctccttg
     4441 cctattatac gacataaaag acttaaatga acggagcggt tttgtaatcg ctccgtttca
     4501 ggtgacagcg gaacgaccta tcgttttaat ccaaccggat tgctttgaaa tcccctccga
     4561 atccgattgg gatttctctc gagagaaaaa cgaattccct tcgaatgaaa tcgaaatccc
     4621 atccgaatcc gaggagaagg aacgatacgc ttaccatttc tccctgttta ccagcccttt
     4681 gctaaaagga agccaagata aactagtcct atcccgtagc aaaacgatcc ggaaagatcc
     4741 ctctttctca cccggcaagg cattcttcgc cgcagtagaa cgatatatcc gctcctatgt
     4801 ctacctttgc cataccccgg aaaccggaac ttggatgggt gggacaccgg aaatcttgtt
     4861 atccggcgag aaaggcgact ggcaaacggt agctttggcc ggaacccaat ccttacgaga
     4921 cgggaaatta ccgaaaagct gggaccataa gaattggaga gaacagcaat tagtcgcctc
     4981 ctatatacgc cgccagctgt ccaccttggg tattactccc gaggagaagg ggccttattc
     5041 agcccgggcc ggagaggttt cccatttgaa aagcgatttc ttcttctcct tgccgaatcc
     5101 cgagaagctg ggtgatgtcc ttcaactatt acaccctact ccagccgttt gcggtcttcc
     5161 caaggaggag gcttatcatt tcatcatcga gaatgagggg tacgatcgta gctattactc
     5221 cggtttcatc ggttggctgg atcccaaagg caaaacagat ctgtacgtaa acctccgttg
     5281 catgaatatc ctcccccaaa cctttacgct gtatgccgga ggcggtctgt tggcggcctc
     5341 gcagctagag gatgagtggc aggagacaga ggataaatta gatacgatgc ggagaatagt
     5401 gggtaattta taattttata tcatataatg tatagcgata aaaagaacat ccttcaattg
     5461 gtagccttgc tgatagagca cggcgtaagt aatatcgtgc tatgtccggg gagccggaac
     5521 tctccgattg tgcacacatt ggcaaaccat tcgttcttca attgccattc cgtgacggat
     5581 gagcgaagcg cgggattctt tgccgtaggg ctagcgttgc acggaggtaa gccggcggct
     5641 gtttgctgta cctcgggcac ggccttgctg aatatacatc cggcggtagc ggaggctttc
     5701 tatcagaaag ttccgcttgt cgtgatatcc gccgaccgcc ccgccgcatg gatcgggcaa
     5761 atggacggac agaccttgcc gcaacccggg gtgttcggct cgctggtgaa gaaatcggta
     5821 cagctaccgg aaatacatac ggatcaagat gaatggtatt gtaatcgatt gatcaacgag
     5881 gctttgttgg aactgaacca tcacggcaaa gggccggttc atatcaacgt cccgatctcc
     5941 gagcctttat ttcagttcac gacacccgaa ttgccgaagg tacgggtaat cacccgttat
     6001 caaggcctaa acgtgtacga ccggaaatat gacgatctga tcgagcgttt gaacaaatat
     6061 agcaagcgaa tgatgatagc gggacaaatg agtttgatct atctcttcga gaagaaaata
     6121 tgtaagttac tatacaaaca tttcacttgg ctctccgagc acatcggcaa ccgtatcgta
     6181 ccgggattgc cgatcaagaa tttcgacgcc atcctgtacg ctaccccaga ggaggaaaaa
     6241 gagaagctgg ttcccgagct cgtgatcacc tacggcggcc atattgtctc caagcggctg
     6301 aaagagtttt tgcggaaaca cccgcctaag gagcattggc atgtctcatt ggatggggag
     6361 gtagcggatt tattcggtag cctgaccacg gtgatcgaga tggacgcttt cgagtttctg
     6421 gagaaaatcg cttatatgct ggagaatagg cagattgaat atccgaaggc ttgggaatat
     6481 aaatcccgga atctgccgga gccggagttc gcttactccg aaatggcggc gatcggtggt
     6541 ttgatacgtt cgcttccggc tgaatcggcc ttgcatctgg ggaatagctc caccgtacgt
     6601 tacgcacaat tgtacaccgt acccgagacg gttgaggttt gttgtaaccg aggtacgagc
     6661 gggatcgaag gctccttgtc tacggctatc ggatacgcct cggcctcgca aaaactaaac
     6721 tttatcgtta taggcgatct tagtttcttc tatgatatga atgcgttgtg gaacggaaac
     6781 ttgcacaata accttcgtat cctgctcttg aacaacggag gtggtgagat cttccaagcc
     6841 ttgccaggat tcaagatgaa cgagcgtacg caccgttacg tcaccgcctc ccaccagacc
     6901 tcagcggagg gatgggccac ggaaagggga ttctcctact ccgccgttca taacgccgag
     6961 gagttggcag ctgcgatgag cgcctttacc caaacggagc aaccgagcga acatccccta
     7021 ttcatggagg ttttcacgga caaagcggaa gacgtacgat tgctcaagga atattatcat
     7081 caactaaaaa attcatccca agcacaaaac atataatata tggaaacgaa aagagaatgg
     7141 acaaccatca aggaatacga ggagatctta tttgatttct acaacggcat cgcccgcatt
     7201 acgataaacc gggaacggta tcgcaacgct tttaccccga ctacgaccac ggagatgagc
     7261 gacgcctttt acatctgccg ggaacgtccg gacattaacg tagtcgttct gacaggagcc
     7321 ggagatacgg cgttttgcgc gggaggcgat atgaacgtga aaggacgtgg cggctacgtg
     7381 ggtaaagacg gcgtacctcg cttgaacgta ttggacgtac aaaagcagat ccgctctctc
     7441 ccgaaacccg tcatcgcagc cgtgaacggt ttcgctatcg gcggcggaca cgtattgcac
     7501 gtggtttgtg accttacgat cgcttccgag aacgctatct tcggacagac aggccctcgt
     7561 gtgggtagct tcgacgccgg gttcggctct tcttacctcg cccgtgtggt cggacaaaaa
     7621 aaggcccgtg agatctggtt cctatgccgc aagtacaatg cacaggaggc tttggatatg
     7681 ggtctggtaa ataaggtagt ccccttggat aaattagagg acgagtacgt tcaatgggcc
     7741 gaggagatga tgttgcttag cccgttggcc ttgcgcatga tcaaggcagg cttgaacgcc
     7801 gagttggacg gacaggccgg tatacaggag ttggccggag acgctaccat gctttactat
     7861 atgacggacg aggcgcagga aggcggcaag gcattcttgg agaaacgccg tccacgcttc
     7921 gaggattacc cgaagttccc gtaaagggaa ttgagaattg agaattgaaa attgaaaatg
     7981 aatggtgaag gagaggtttt ataagacaga ggtggttccc cggtgcttga ctttcaagca
     8041 accggcagga acctcacggg gtgtttacac gacccggaaa ttgtgggagg tccgaatccg
     8101 caaggaagac gaaccctcgg ttattggtat cggagaatgt gcccccctgc cggatctcag
     8161 ttgctattat ggagtggatt acgagatcac gttatccaag gcttgcctcg atctggaaca
     8221 tgagggatat gttgacaccg aatctttgcg ccattaccca tccatccttt tcgggctgga
     8281 gacggccatg cgccattatg aacagggcgg ttggcggcat tacgacacgc ccttctcgcg
     8341 ggggcaggcg ggcatcccca tcaacggact gatctggatg ggcgattata agtacatgtt
     8401 ggaacaggta gaggaaaaga tgaaggaggg cttccgctgc gtcaagctga agatcggcgc
     8461 tatcgatttc gaccgggaac tctctttatt gaaacacatc cgtgcgcatt tctctgccaa
     8521 ggaaatagag cttcgggtag acgccaacgg cgctttcaca ccctcggagg cgatggacaa
     8581 actgaagcgg ctcgccgaga tggacttgca ttccatcgag cagcctatcc gtgccgggca
     8641 gttggaagaa atggcacacc ttgcggcaga gtcacccctt cccatcgctc tcgacgagga
     8701 actgatcggc tgtaacgccc cggacgagaa acggcggttg ttggaaacga tccatcccca
     8761 atacattata ttaaagcctt ccctccacgg aggcatcgcc ggatgtacgg aatgggttca
     8821 cttagcggaa actatcttag ggagtacccc cgagcgaccc aaatggtggg tcacctccgc
     8881 tctggaatcg caaatcggac tgaacgctat cgcccaatgg tgcgccacgt taggtaaccc
     8941 gctaccgcaa ggtctgggaa ccggcgagat tttcaaggat gataaacatc ggttaatcca
     9001 acgaaaagga gacaccatct ggttcactaa cgacctttga cctatgccga tacaagaaga
     9061 tttacaggca ttcttagctg aatggcacga tccctcccct tttctggaag tccagacctc
     9121 cggctccacc ggtacgccca agcggatgag agtgcgcaag gaccggatgc tgaacagcgc
     9181 ccggcttacc tgcgattatc tgggtcttaa gaagggcgac aaggccctgt tatgtatgcc
     9241 cctgcgctat atagccggaa agatgatggt ggtccgctcc ctatacgccg gactggatct
     9301 ggaggtgcgt gagccctccg gacacccgtt ggcggattgg ggggatacgc ccctgcgct
//
