LOCUS       c00306_gnlPro..        23307 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBOGFACI_306.
ACCESSION   c00306_gnlPro..
VERSION     c00306_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:07:40
            Original ID  :: gnl|Prokka|PBOGFACI_306
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 622
            Orig. end    :: 23929
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23307
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10622:15485]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14863
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..23307
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23307
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(519..1079)
                     /locus_tag="ctg306_2"
                     /transl_table=11
                     /translation="VYKQMEEFELSEQCRLGNNRARKELYEHYGGRLLGVCLRYTGDRD
                     TAQDLLHDGFIKIFSSFDKFTWRGEGSLRAWMERVMVNTALQYLRKSDVISQSTPLEEV
                     PEDYEEPDALAVEMIPQAVLMRFIEELPAGYRTVFNLYTFEEKSHKEIAQLLGINEKSS
                     ASQLFRAKSVLAKRVKEWIMNNG"
     CDS             1481..1966
                     /locus_tag="ctg306_3"
                     /transl_table=11
                     /translation="VIFKELEEPVKGYDYNIQVREIKEILTKEIVTMGEGENTEEKIGD
                     DKINSTYMWITQDKKYLTIEFQYYGTHSEDKKHFLNLVINNKEAEPAANDANDEYINLE
                     FRHNDEGDTADRLGEGYISFKLDKIQDQMKGKKGLRIRVNTLYNREKFYEVEFPASN"
     CDS             complement(2085..2774)
                     /locus_tag="ctg306_4"
                     /transl_table=11
                     /translation="MKKYIAEMIGTMVLVLMGCGSAVFAGSMAGTVGAGVGTVGVALAF
                     GLSVVAMAYAIGGISGCHINPAITLGVFLSGRMNGKDAGMYMLFQVIGAIIGSAILYAL
                     VTTGGYDGPTATGSNGFGDGEMLQAFIAEVVFTFIFVLVVLGSTDPKKGAGAFAGLAIG
                     LSLVLVHIVCIPITGTSVNPARSIGPALFQGGEALSQLWLFIVAPFVGAAVSALVWNYF
                     GDKNEKK"
     CDS             3063..3242
                     /locus_tag="ctg306_5"
                     /transl_table=11
                     /translation="VERNTPTQQTVSEFDPDQYVYGVHRFLFRSRFRQRGYLFYHYGND
                     TSDQCTASPSAGQQ"
     CDS             complement(3604..3801)
                     /locus_tag="ctg306_6"
                     /transl_table=11
                     /translation="MAFQPSPYFSSLKIDNEGADYDNHSCNGTECRILSREHDPAKYGA
                     QYRVDQSAHIDITHFGSFTL"
     CDS             complement(3835..4761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.1; E-value: 5.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg306_7"
                     /sec_met_domain="LysR_substrate (E-value: 8.5e-43,
                     bitscore: 136.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.8e-19, bitscore: 60.1,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIQQLEYILAVDQFRHFARAAEYCRVTQPTLSAMIQKLEDELGV
                     KLFDRTVQPVCPTAIGEKIIDQARVILAQTAQVKEIISEEKQSLAGVFHLGVLPTIAPY
                     LLPRFFPQLMEKYPELDIRVTEMKTQNIQQALHAGDIDAAIIASKLEDTFLKEETLFYE
                     TFFGYVSCKEPLFKHDVIRTSDITGERLWLLDEGHCFRDQLVRFCQMETVKVNQMAYHL
                     GSMETFMRMVESGKGITFIPELAVSQLNEEQKKLVRPFAIPRPTRQIVLATNRDFIRHS
                     LLNVLKEEILAAVPKEMQSLQSIQYLL"
     CDS             5067..5375
                     /locus_tag="ctg306_8"
                     /transl_table=11
                     /translation="MYDDTAEKVDEIAERILMLGGTPANKFSDYLKVANINEVDKVSNG
                     EQALDNILQSISYLIGEERKILSIASQAGDEVTVSMMSDYLKEQEKMVWMLTAYNSK"
     CDS             complement(5473..7353)
                     /locus_tag="ctg306_9"
                     /transl_table=11
                     /translation="MKKHSTLVAAILAISGSLTGCQEVKSPEPVLPIPQEKQVNWQKME
                     TYAFVHFGLNTFNDREWGYGDSDPKIFNPARLDCEQWVQTFVNSGMKGVILTAKHHDGF
                     CLWPTQLTEYCIRNTPYKDGKGDIVRELSDACKKYGIKFAVYLSPWDRHQANYGTPEYV
                     DYFYKQLHELLTNYGDVFEIWFDGANGGDGWYGGAKDARIIDRKTYYDYPRAYKMIDEL
                     QPQAVIFSDGGPGCRWVGNESGFAGATNWSFLRAGEVYPGYPKYRELQYGHADGNQWVA
                     AECDVSIRPGWFYHPEEDNRVKTVDQLTDLYYRSVGHNGTLLLNFPVDRNGLIHPTDSL
                     NAVTFHQRVQKELADNLLSKAKVSASDERGGQFNVRALTDGQYDTYWATNDSVMAADLT
                     FTFEQPTKMNRVMIQEYIPLGQRVKSFVVKYKKGDQWLSVKCNEETTTVGYKRLLRFET
                     IETEQLRIRFTDARACLCINEAGAYYAPDATESYTSATSELRSFPFTIVGVDEEEVKKC
                     SDKDDQTTAFIPGKEIVIDLGESRTLHSFYYLPDQSEYSKGLISSYELSAGSTEETMQV
                     IAKGEFSNIRNNPILQSVYFSPVEARFLKLKATRMVDESDSLGLAEVGCQ"
     CDS             complement(7869..8816)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 48.9; E-value:
                     1.3e-15)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg306_10"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-16, bitscore:
                     48.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLC
                     MNLRYIGAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEK
                     EKLKQTEILIIGGGAVDKALEEEIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYY
                     PFSSVELFLSSENTLMINAPLVCNEILQTNDIARIYPDGSFTILGRKDNVINSGGIKVQ
                     AEEIEKLLQSFIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKY
                     IYTVNHIPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(8972..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg306_11"
                     /sec_met_domain="MR_MLE_C (E-value: 8e-30, bitscore: 94.5,
                     seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNRVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg306_12"
                     /sec_met_domain="ECH_1 (E-value: 3.8e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(10829..12496)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg306_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.3e-08, bitscore:
                     24.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPLVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKIGQMIPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYPVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIAIGDLSFFYDMNALWNINVRSNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFTNKNKDARILKDYYHQLKQK"
     CDS             complement(12516..13628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg306_14"
                     /sec_met_domain="Chorismate_bind (E-value: 2.8e-57,
                     bitscore: 184.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     YDLKELNGQRGFVIAPFRVDKSCPIVLIQSDRTGQPLPMEIVADEEQVLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDTTFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLLLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(13625..14863)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg306_15"
                     /sec_met_domain="HBT (E-value: 4e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSMKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLAS
                     GRPTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARK
                     NNFALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEE
                     ALVSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGD
                     GVCDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRATEIPL
                     DQLNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGL
                     GSMILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLV
                     SSIRVVNSVMKKR"
     CDS             complement(14942..15304)
                     /locus_tag="ctg306_16"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(15375..17171)
                     /locus_tag="ctg306_17"
                     /transl_table=11
                     /translation="LGSKIIGIIMKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSE
                     YISRIYMAEPERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLD
                     SVSQKDPKHLLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGE
                     NKWQLSFKEEAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRNKEALEVGL
                     KREKLLKDIAKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQT
                     PDGKTYAIPYLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFE
                     KVAALRESIISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLG
                     CVTCLILFVLWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLD
                     LEPETGFSEKDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIV
                     HLNNARFARMIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILY
                     SMFKKKTGMTPYEFKKAQESLG"
     CDS             complement(17523..18290)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg306_18"
                     /sec_met_domain="Acetyltransf_1 (E-value: 6.5e-08,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVSVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             complement(18331..18531)
                     /locus_tag="ctg306_19"
                     /transl_table=11
                     /translation="VRYSSCFFLGSFFDHFFHRVVNKFFDKFVTQVYLLICFPNFNPYY
                     CVILTRLDNVLLLSIVYLCCS"
     CDS             complement(18627..19877)
                     /locus_tag="ctg306_20"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFAQMPEIKLGQSISFEEYLNRV
                     AKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLETVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALERACGIWDICF"
     CDS             complement(19855..22962)
                     /locus_tag="ctg306_21"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVVLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITGFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSVTTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPVFYYLVENNVLNKKKNDEKEYTI"
     CDS             complement(22969..23307)
                     /locus_tag="ctg306_22"
                     /transl_table=11
                     /translation="VIKGNVYHVEEEVDEETRSIQVLSICDNLNGHLKLGMYTTVHFLS
                     VPVRQIQIPEKALLQGEKDSYVFVQIAPLVFVRTSVTVETTENGIAVISEGLRPGDKII
                     SEGGYYLK"
ORIGIN
        1 gggcttatgc tgggcggcct tcgtttcttc caccggttcc acttcttctt tttctttccg
       61 gtcgccggtc tgagcgttca gctccgaagg ctgctcttct ttcttcaccg gttcgtcgat
      121 atttgccgtc ggctggggaa tgttccgttc cgctttcgcg atgcggttct tcactaccgg
      181 acgcactacc ggttctatcg ttgttcctgt catatccggt tgctgcgcat ccggcaaaac
      241 atccggaaca gaggctaacg ccggagtctt ggcatgacga atttcatcag cagcaggagt
      301 tccgaggaaa tacaggctga ccgatgacac caaagccaat aaaatgacag ccgcagcggc
      361 taccgtccat ttacgataag gatatatctt cctctccaca ggaggcataa gttctttttc
      421 cagttgttcc caaccggaag caggaagcgg ctccgagtaa ttcccgagct tctccttcaa
      481 cttattcatc cataattctt tctcttccat atctctacct atccgttatt cattatccat
      541 tcttttactc tcttagccaa cacgctcttc gcccgaaata attgcgaagc cgatgacttc
      601 tcattaatac ctaacaactg tgctatttcc ttatgcgatt tttcctcgaa ggtgtaaagg
      661 ttgaacacgg tacggtatcc tgccggcaac tcttcgataa atcgcatcaa taccgcttgc
      721 ggaatcatct ctacagccaa agcgtcgggt tcctcgtaat cttcgggtac ttcttccaaa
      781 ggcgtagact gactgattac atcactcttg cgaagatact gtaaagcggt attgaccatc
      841 acccgttcca tccaggcccg aagtgagcct tcaccccgcc aggtgaactt gtcgaaagaa
      901 ctgaatatct ttataaaacc atcgtgaagc agatcctgag ctgtatcacg gtcgccggta
      961 tagcgcagac agacgcctag caaacgccct ccataatgct catacaattc tttgcgggct
     1021 cgattatttc ccagcctgca ttgttccgac aactcaaatt cttccatttg cttatacacg
     1081 tgtttacctt ataaatgcag caaagataga aatactgcac agagagaaca actcttttgc
     1141 aacttttgtt tctttaacag atccaaatgc aatattttct ccccctttgc attttcagag
     1201 tacaaagcaa gtaaatagta ctcattaaaa aacattttta tagtatatga agaaatttaa
     1261 attcattgca ttttttattg ctgttatgac cacaatgccg atacttcagt cgtgtctgga
     1321 tgatgactcc tcatccgatt cactggtcat cggcaccatc aatctgatca gcccggatag
     1381 caaggatttc tatttcactc tggatgatgg aaaaacaatg ttcccgagca atggaaacgg
     1441 atggatcagt gacaagaata aagacgggca acgcgccttt gtgatattca aagaactgga
     1501 agaaccggtg aagggatatg actataatat tcaggtaaga gaaataaaag agatcctgac
     1561 caaagaaatc gtgactatgg gggaaggaga aaatacggaa gagaagatcg gagacgataa
     1621 aatcaattct acttatatgt ggattaccca agacaagaaa tatctgacaa tcgaattcca
     1681 atattacggc acgcatagcg aggacaagaa acatttcctg aatctggtca tcaacaacaa
     1741 ggaagctgaa cctgctgcca atgatgccaa cgatgagtat atcaatcttg aattccggca
     1801 taacgacgaa ggcgacaccg ccgaccgtct gggcgaaggg tatatatctt tcaaactgga
     1861 taagattcaa gatcagatga aaggcaagaa aggactcaga atacgtgtca ataccttata
     1921 taacagggaa aaattctatg aagtggaatt ccccgcatct aattaaatct agtaattata
     1981 gaaacactct ttttattata atatataatt acgcaaaaga gggcgacagt tgtgaaactc
     2041 tcgcccttaa ttttatcata aagtgatccg tttatttctt cttattattt cttttcattc
     2101 ttgtcaccga aataattcca gacgagcgca ctgacagccg ctcctacaaa cggcgccaca
     2161 ataaacagcc ataactgcga caacgcttct ccaccctgga acaatgccgg accgatgcta
     2221 cgtgccggat tgacggaagt acctgtaata gggatacata cgatatgcac caataccaaa
     2281 gaaagaccga tggcaaggcc tgcgaaagct cccgcccctt tcttcggatc ggtagacccc
     2341 agcaccacca atacaaaaat gaaagtaaag accacttctg cgatgaatgc ctgtagcatc
     2401 tcaccgtcac cgaagccgtt ggaaccagta gccgtcggcc cgtcgtaccc gccggtggtc
     2461 accagggcat aaagaatagc cgaaccgata atcgctccta taacctggaa aagcatatac
     2521 atacccgcat cttttccatt catacgaccc gagaggaata ctcctagcgt aatagcagga
     2581 ttgatgtgac atcccgaaat acctccgata gcatacgcca tcgccactac tgaaagtcca
     2641 aatgccaaag caacgccgac cgttcccacg ccggctccta cagtaccagc catactgccg
     2701 gcaaaaacag cacttccaca tcccatcagg acaagcacca tcgtcccgat catttctgca
     2761 atgtattttt tcatattact aaataaaaaa tggttgattc tccaaatata aggaattaat
     2821 acctagattc aaaatgtatg tgcctaatta ttactatctt tgcagcattt ttgaataaaa
     2881 ccaccaaacc ataaaatgaa aaaaggactt ttttatgcta tattggcctc tgtattatgg
     2941 gctatcgtca atccgtttat caagcaggga ctgagttacg acttttcgcc gatgaacttt
     3001 gcaggaatcc gctttaccac tgtaggcatc attctttttg cttatacctg gcataagggg
     3061 atgtggaaag aaatacgcca acacagcaaa ctgtttctga atttgatcct gatcaatatg
     3121 tttatggggt acaccgcttt ctatttcgga gtcgatttcg tcagcggggc tatctcttct
     3181 atcattatgg gaatgacacc tctgatcaat gtactgctag cccatctgct ggccagcaat
     3241 gaccggctga atgtgcacaa gattatcagc cttattgtca gcctcatcgg tttgctgctt
     3301 atcgtaggca tgggtagcaa tggcgctccg ctggactgga aagggatcac gggaattgta
     3361 cttttgctgc tcagtatcat ctttcaggga tattccgcga tttcggtatc agaagataaa
     3421 ggcaagataa accctatttt cctgaatgcc gtgcagatgt tcttcggcgg actgctcatc
     3481 tatatgatag gattaggtac ggaagggtat cattcattta tcggaaagcc tgccggattc
     3541 tatatcagtc tttctattct ggtatttatc tcggtctttg ctttcagttt ctggtttatc
     3601 gccttacaga gtaaaggagc caaagtgagt gatatcaata tgtgcagact gatcaacccg
     3661 atattgggcg ccatacttag ctggatcatg ctcccgggag agtatccgac attcagtacc
     3721 gttgcaggaa tgattatcat agtcagctcc ctcattatct attttaaggg agctgaaata
     3781 gggcgatggt tgaaacgcca tacagccgga agcagtacgc aggaataagc aatattacag
     3841 caagtactga atggattgca gggattgcat ttctttgggt actgctgcca gtatctcttc
     3901 tttgagtaca ttgagcaggc tatgacggat aaaatcccta ttggtcgcaa gcactatctg
     3961 ccgtgtagga cggggaatgg caaacggacg taccagtttc ttttgttctt cgttcagttg
     4021 cgaaacagcc agttcgggaa tgaaggtgat tccttttccg ctttctacca tacgcataaa
     4081 ggtttccata cttcccagat ggtaggccat ctgattgact ttgaccgttt ccatctggca
     4141 gaaacgtaca agctggtcac ggaagcaatg cccttcgtcc aatagccaga gacgttcgcc
     4201 cgttatatcg gaagtgcgta tcacgtcgtg cttgaacaga ggttctttgc aggatacata
     4261 tccgaagaat gtttcataga aaagtgtttc ttctttcagg aaagtgtctt ccaatttgct
     4321 ggctataatt gcggcatcaa tatctccggc atgcaatgcc tgctggatat tctgtgtttt
     4381 catttctgtg acacgtatat ccagttccgg atacttttcc atcagttggg ggaagaagcg
     4441 gggaagtaaa taaggtgcta tggtaggcaa tacccccaaa tggaacacgc ctgccagtga
     4501 ctgtttctct tcactgatta tttctttcac ctgcgctgtc tgtgccagaa tgacacgtgc
     4561 ctgatcaatg atcttttctc caatcgctgt gggacagacc ggctgcaccg tacggtcaaa
     4621 caacttcact cccagctcat cttccagttt ctggatcata gcactcagcg tgggctgcgt
     4681 cacgcggcaa tattccgccg ctctggcaaa atgacggaac tggtcaaccg ccaatatata
     4741 ttctaattgt tgtatcgtca tctatcaaat atgattaagt tatagatttc ttctatgcaa
     4801 agatagaaat tatcagtttg acaacaagca ttttccgcct tatctttgca gtacagaaaa
     4861 aaagaaaacg aatataaatc attaaaaaca aatagaatat gaaaacttta gaatttatca
     4921 aattgaacga atcgggagca aacaacgtag tagcatcttt gcaacaatta ctggcagact
     4981 tccaagtata ttacaccaac ctccgcggtt tccactggaa tatcaaaggg catgacttct
     5041 tcgtacttca cagccaattc gaaaagatgt atgatgacac tgccgaaaaa gtggacgaaa
     5101 tcgcagaacg tatcctgatg ctgggcggta ctcctgccaa caaattcagt gattatctga
     5161 aagtagccaa tattaacgaa gtggataagg taagcaacgg agaacaggca ctggataaca
     5221 tactacagtc tatcagttat ctgatcggtg aagaacgcaa gattctgtct atcgcttcac
     5281 aagccggaga tgaagtaacc gtttcgatga tgagcgatta tctgaaagaa caggaaaaga
     5341 tggtttggat gttgacggct tataacagca agtaaataca aggtttaggt tttaagtgaa
     5401 agtgagtaaa agtggaacgt atcgtaaagc aatacgtccc acttttcgtt tatgacttga
     5461 actctgagtg gattattgac atcccacttc ggctaatcct aaagaatcac tttcgtccac
     5521 catacgtgtc gctttcaatt taagaaaacg ggcttcaaca ggactaaagt atacactctg
     5581 aagaatcgga ttattgcgga tattcgagaa ttctcctttt gcaataacct gcatcgtttc
     5641 ttcagtcgaa ccggcagaca attcgtaaga tgaaatcaaa cctttactgt actcactctg
     5701 atcgggcaaa tagtagaatg aatgaagggt acggctttca ccgagatcaa tcacgatttc
     5761 tttcccgggg ataaaagcag tagtctgatc gtctttatcg ctgcatttct tgacttcctc
     5821 ctcatcaacg cccacgatag taaacggaaa actcctcaac tccgaagtgg cagatgtgta
     5881 actttccgta gcgtcgggag cataataagc tcctgcttca ttgatacaca agcacgcacg
     5941 ggcatctgta aagcgtatac gcagctgttc cgtctctatc gtttcaaaac gcaacagacg
     6001 tttgtaacct acagtcgtag tttcttcatt acatttgacc gacaaccact gatctccttt
     6061 cttatatttg accacaaaag atttaacacg ctgtcccaaa ggtatatact cctgaatcat
     6121 aacccggttc atctttgtcg gctgttcgaa agtaaaagtc agatcagccg ccatgacgct
     6181 gtcattggta gcccaatagg tgtcatactg tccatctgtc aaggcacgga cattgaactg
     6241 acctccacgc tcatcggaag ctgaaacttt ggctttactc aataagttgt ctgccaattc
     6301 tttctgaacc cgctgatgga acgttactgc attcaaagag tccgtcggat gaatcaaacc
     6361 attgcgatct accgggaaat tcaataataa agtaccatta tgacctacac tccggtaata
     6421 caaatccgtc aattgatcga ctgtcttcac tctattgtct tcttccggat gatagaacca
     6481 tcccggacgg atagatacat cacattcggc agccacccat tggtttccgt ccgcatgacc
     6541 atactgtagt tcacgatatt tgggataacc cggatatact tcgcctgccc gaaggaaaga
     6601 ccagttagta gctccggcaa atccactctc atttcctacc caacggcaac ccggtcctcc
     6661 atcggagaat atcacggctt gcggttgcag ttcatcgatc attttgtaag ctcgcggata
     6721 atcataatat gttttgcgat caatgatacg tgcatctttc gctcctccat accaaccgtc
     6781 gcctccattg gctccatcaa accagatttc gaatacgtct ccataattag tcagcaactc
     6841 gtgaagttgt ttatagaaat aatctacata ttccggagtg ccgtaattag cctgatgtct
     6901 gtcccacgga gagagatata cggcaaactt aatcccatac ttcttgcagg catcggaaag
     6961 ttcacggacg atgtctcctt taccatcttt gtaaggagta tttcgaatac aatattcagt
     7021 cagttgggta ggccacagac aaaagccatc atgatgcttg gctgtcaaaa tcactccttt
     7081 catgccggag ttgacaaaag tctgcaccca ttgttcgcaa tccagacgtg caggattgaa
     7141 aattttcgga tcagagtcac catatcccca ttcgcggtca ttaaaagtat tgagaccgaa
     7201 atgtacaaag gcataagttt ccatcttttg ccaattgact tgtttctctt gcgggatggg
     7261 taaaacaggt tctggtgatt tgacttcctg gcatcctgtc agtgagccgg aaattgccag
     7321 aatggcagcg actaaggtcg agtgtttttt catgtttatt caattagggg gtttaatggg
     7381 tgcaaaaata agtttaatat cctgatatat gactctagta tattgttatt tagttttttt
     7441 tgtatctaga cagtatacaa actaatgtat ccggggatat ttctcatccg tatctcccac
     7501 ttcttctcgc aatttcatta tttcctattt catctgcttt ataataaagg catactcctt
     7561 catcattatt cacattatgg tcttccttcg gatctttttg caaatcataa aaattccaca
     7621 aaggggtagt cggaacttct tacccatccg tcatgtccaa tggatcacca tcaatgaatc
     7681 ctccaatggg taaactccat ttttatggct atatatttcc gtaagttatg aaaagtttct
     7741 ttgaaggcaa aacacatgcg gaaattgccg aagaaatgaa tctcagcgta aaatccatta
     7801 atcggtataa acaaaaaaca atggaactcc tgcggaacga gttgaaagat tacctcccgc
     7861 tgtttttatt attcctgtct cccgagcaac tgtaagctct ctgctaaaac acggcactct
     7921 ttacgattaa tcttcccatt tcccgtttga ggaatatgat ttaccgtata aatatattta
     7981 ggacgataat aagatgctaa gactgattcc aatttagtcc ctagcgcact tatctccatc
     8041 tgcccttcta tcaataaagt aacagcctgc cccaaacgcc gatccggaac ggaagtgatc
     8101 acaaacggta cagggataaa cgactgaagt aacttttcga tctcttctgc ctgcacttta
     8161 attcctccgc tattgattac attatccttt cttcccaaaa tcgtaaaact gccgtccgga
     8221 taaatgcggg caatatcatt cgtctgcaga atttcattgc agacaagcgg agcattaatc
     8281 atcaaagtat tttctgaaga caaaaacaac tctacggatg aaaaaggata ataacgatcg
     8341 gatgctgctg cgccattcag acggcgaaga gcgatgtgag aaagggtttc cgtcatcccg
     8401 taagttgaat aaacagcatt ggacagattt ctgatttctt cctctaaagc cttgtcaact
     8461 gctccgcctc ctataattaa aatctccgtt tgctttaatt tctctttctc ttcgggtatc
     8521 tgaaatgtat tatacacctg caaaggcacc atagccgcaa accttaaagg agtgtccaca
     8581 tctgccaatg gatgaccgga agcccgacgt actataagat tcaacccggc aatcaaagaa
     8641 cggacgacta ccatcatcgc cccgatatag cgaaggttca tacacaataa tgccgtttca
     8701 ccctgcttta aatccagaaa ctcacaagtc aggcgtgcac tctgtatcat ctgatctttg
     8761 cgaacaagca attctttagg tgcccccgta gaaccggaag tatgtacagt gatcacagga
     8821 tcatcattaa accattcgtt tagaaaaaga tataaatccc atatagcaga agggtggttt
     8881 ccctcacctt ctgctacaag gctatgtata tcgcccggag tatattcctt tccctccagc
     8941 aacaaacgct gtttttgtcg gtcgaatatc atcatttaca aaaccacaaa caatcttttc
     9001 tgatttcaag aggcatctct acattatctg taaaaagtaa tccggtgcct aacccttgag
     9061 gcaatggatt ctgaaaagtg gcgcaccatt gtgcgatagc attcagaccg atattagact
     9121 ccagagcaga agttatccac caaccgatat tcagtttctc cgcttctgca atccactcct
     9181 cgccaccggc taatccgcca tgaagagaag gtttgataat aatatattgc ggacggatag
     9241 ccgaaagtaa tctttgcttt tcttcccagg tattatagcc tatcagttcc tcatccaaag
     9301 ctatcggcaa aggagattcg gaagtaagac gtgccatttc ttcccattgt ccggcacgaa
     9361 tgggctgttc tatcgaatgt aagtccagtt cggacaagcg tttcaatttc tccatcgcat
     9421 ctgttggcga gaatgctccg ttggcatcta cacgcaattc tatttcttta gaagaatagt
     9481 gagagcggat atgttggagt aaagccagtt cttcttcaaa gttgatggca ccgatcttca
     9541 actttataca gcggaatccc gcctccatct tcttctctat ctgagcaagc attctattaa
     9601 agtcacccat ccagataagc ccgtttatcg gaatacctgc ttccccacgt gagaagggtg
     9661 tgtcccacaa agcccaactt ccttcaaaaa agtgacgaat ggctgtctcc aagccaaaaa
     9721 ggatggaagg gtacttgcat agagcttcca tgtccagctt gcctccctga ttctctacct
     9781 gccggcagat tttagccagc acttcctcgt aatcgggaag atcatcacag ctaagatttg
     9841 gcagaggagc gcactccccg atccctaccc gattgggaaa ttcgggagca gtaaaatgaa
     9901 gataccagac ttttcgcgtt gtgtatgtgc ctcgtgaagt tccggccggc tgcttgaaat
     9961 gaagcacccg cggaataatg tctattttgc aatccattgt ttaagggaac ttcggatatt
    10021 tcttaaagtt aggtttacgt ttctccagga atgcattctt tccttcctga gcctcatccg
    10081 tcagatagta aagtaaggtc gcatcccctg ccagctcctg aatacctgcc tgaccatcca
    10141 gttcggcatt caatccggct ttaatcatcc gcaaggccaa cggactaagc agcatcattt
    10201 cttccgccca ttgcacatat tcatcctcca gttgctccaa tggaactact ttattcacca
    10261 atcccatatc caacgcttcc tgcgcattgt atttccgaca aaggaaccat atctcacgtg
    10321 ccttcttctg accgacgaca cgagccagat aagaggcccc gaaacctgca tcaaagctac
    10381 ctacgcgagg tccggtctgt ccgaagatcg cattctccga agcaatcgat aaatcgcaaa
    10441 ccacatgaag cacatgtccg ccaccgatgg caaatccatt cacggcagca attaccggtt
    10501 tcggaatact gcggatttgt ttctgtacat ccagaacact cagacgggga acaccgtcct
    10561 tgccgatata gccgccacga cctttcacat tctggtcgcc gcccgaacag aaagccttgt
    10621 caccagctcc cgtaatcacg atcacatcaa tatccgcttc ttcccggcaa atgcgcaatg
    10681 cgtcactcat ttcagccgtt gtagtcggag taaatgcatt tcgatagcgt tcacggttaa
    10741 tggtgatgcg ggcaatccca ttatagtaat caaagagaat atcttcgtat tctctgatgg
    10801 ttgtccattc tctttgtgtt gacataatct atttttgttt tagttgatga taataatctt
    10861 ttagtatacg tgcatcttta ttcttattgg tgaatacttc catcagaacc ggttgttcca
    10921 tggcttccgg ctgtgtgaag gttttcatcg cttcggcaag ctgttcttca ttctctaccc
    10981 gttgataaag gaatcctcgt tcttccgccc atcctttggc ggatgttttg tgaacggctg
    11041 taatatactt gtgcgacgtg cccgacatat ccagcccggg taatgtatgg aaaatctccc
    11101 ctcctccgtt gttcagcaaa agaatgcgta gattggaacg gacattgatg ttccacaaag
    11161 cattcatatc gtaaaagaaa ctaaggtcac ctatagctat aaaattcagt ttatccgaac
    11221 cggcggcata tcccactgcc gtggacaatg agccttcaat accgcttgta ccccgattac
    11281 agcatacttc aatcgtagaa ggaactgggt ataactgagc atagcggatg acagaactat
    11341 ttgccagatg caatgcacat gattccggca atgcctttat caaagcaccg atagccgaca
    11401 tttccgaata tccgaactcc ggttcgggaa tggtcttgca ataattctcc cagacacggg
    11461 gatattccgg cacacggtta tccagcaacg gagctatttt ctccagaaac tcaaacgggt
    11521 ccatttcgat gacggtagtc agagaaccgt aaaggtcaac cacttctcca tcagcagaca
    11581 catgccagtg ttctttaggc ggatgctgcc gaagatattt tttcaaccgc ttggaaacca
    11641 catgtccgcc ataagtaatc aataactcgg gaatcatctg gccgattttc tcttcgggca
    11701 tcgcataaag cgccgcatca aaattcttca ctggaatacc gggtactgtc tgattaccga
    11761 tatgctcggt cagccacacg aaatgtttat ataacaattt ggtatgccgt ttctcaaaca
    11821 agtaaatcaa gttcatctgt ccgacaataa tcatccgctt ctgatatctg ttcaagcgtt
    11881 cgatcaggtc attgtaatcc cggtcgtata cattcagccc ctgatagcgc gtgatgacac
    11941 gtacttcggg aagcgactcc accgtaaact ggaacaaagg ttcggatata ggaatattaa
    12001 tatgtaccgg accttttcca tgatggttgg tttccagcaa ggcttcattc accaagcgat
    12061 tacagtacca ttcatcctct tctgtctgaa tctccggaag gtttaccgac ttcttgacca
    12121 atgtctgaaa aacaccgggc tgcggcaatg tctgtcccgc catctgtcca atccaggcag
    12181 caggccgatc ggcagagata acaactaaag gtatattctg ataatacgct tctgccacag
    12241 caggatgaag attgagcaac gctgtaccgg aagtacagca aacggcagca ggatgcccac
    12301 cattcagtgc aagaccaatc gcaaaataac cggcactccg ctcatccgtc atagcataac
    12361 aagtaaaacc cggatgagta gacagcgtat gcacaagagg tgcattacgg ctaccgggac
    12421 ataacactac tttcgtaatt ccatgcgcct caagcaacgc gaccaactgg agtatatttt
    12481 tcttgtccga atacatatta atagtgatta gcttgttaat gattcatcat tattggagca
    12541 gacacaagaa tacgcctcat cgtctgcaat ttcttttccg tttcctgcca ttcatcattc
    12601 aattctgaag aggctaacaa tccgccaccg gcatatagtg tcagttgctc gtcttcaatg
    12661 tgcatgcaac gcagattcac atacaaatct gtgcgtccct ccggatcgag ccaaccgata
    12721 aaaccggaat aatacttacg atcgtaccct tcattttcca gaatgaaccg ataggcttct
    12781 tctttaggca gtccgcacac ggcaggagtc ggatgcagga ctttcagaag gtctcccaga
    12841 tttttattat ctttcaaaga gaaatgaaaa tcagttttca gatgtgacag ggcgccggca
    12901 tatgccggat aaggtccgct ctctgtggag cgaatgccca gcaaaagaag ctgccgacgg
    12961 atataggacg ccacataatc ctgctcctga cggtttttgt catcccatac ttgcggaagt
    13021 ttaccattct gcaaaggttg agttcctgcc aaggcaactg tattccattc atttttttcg
    13081 cccgacaata taatttcggg ggtacttccc agccacacgc ccgtctgagg agtataacac
    13141 agatagatat aagaatgaat ataacgttga caagctgcac gaaaaacagc tgaaggggaa
    13201 aactccggat tctttccaat agtgagacta cgggaaagca ccagtttatc aaaggtagta
    13261 tcacgcaagg cttcaataaa tgtatgaaaa caggtcgcat acttccctgt acaaagggta
    13321 tgaaaagatt cctccggata actctgcaag acctgctctt cgtctgccac gatttccata
    13381 ggcaacggct gtccagtcct gtcggactgt atcaacacaa tcgggcatga cttatctaca
    13441 cggaacggag caatcacaaa tcctctttgt ccattcagtt ctttcaaatc gtaaatcagg
    13501 cggacagctc cgacatcttc agtcaacaga cgaggatact tctccccggg aacacgataa
    13561 acagcaaagg gctgtttccg ctgaatgagt gcatcaatag ttgtcaagtt acttttttcg
    13621 tcaatcatct ttttttcatc acactgttga ccacccgtat agaggacacc agtttattgg
    13681 ttgaagtaaa aacgtccaca ttccatacat gagaggaacg tcctttatgt acaatcgtcg
    13741 ctactgcacg tactgtatca ccttcgtgcg cagaagatat atgatttccg ctgacctgca
    13801 ttcctaccac aatttcatcc ggctgacaga gaatcatcga gccgagtccg gcaactgttt
    13861 ctcccaatgc aagcgtagct ccaccgtgca aaataccgaa cggctgacgg gtacggtgat
    13921 ctaccggcat cgtcgcctct acacggtctt cgtcggcata tgtatattgg atacccagat
    13981 tacccatcaa tgcgtgacgc gcctgtgcat tcaactggtc caaaggaatc tctgtagcgc
    14041 gaacttccgc tattatcgcc ttttcgacag ccagagccac tccgtcttcc tcattggaag
    14101 ctgtcacata atccgcacag acctttaccg aatcctgcga atgccccatc gccactccca
    14161 gtcctgccag ctgaatcatc gttacatcgc acacaccgtc tcctatagcg atgacttctt
    14221 cacgcttcac atccagttct tccaataaag ctcccaatgt gttggcttta tcaatcgcac
    14281 acggcactac ttccagaaaa taaggttcgg aacggaaaac atccaaagct ccgttcaacc
    14341 gtctcttcca gtgtccttcc agactaacca gcgcttcttc gtcatcgctg acaagcatac
    14401 acttacacgg agcaaagtca attgctacag aaaattcctc ttccttgatc actttcaaat
    14461 tattcaagcg agcttcattc tggatatgtt cattctccgg agtgtcagta atgatcgtat
    14521 catcatggta agtgaacagt gcgaaattat tttttcttgc cttcttttcc agataaggca
    14581 acatttccgg attaatcctc cgctcaaaca gtatttctcc gttttgagca ttaattatct
    14641 ggcaaccatt ataagaaagg atataacctc cataatttcc gagttctagg gatttggcta
    14701 aaggcatcag accgtaagtc ggtcgaccgg atgccaacac gatacgtact cccatctgct
    14761 gaactttcag caaagcagcc aatgtacgtt tactaatttc ttttgcatca ttgagaagcg
    14821 ttccgtctac atcaagaact aataatttat acttcatgga cacacgattt tgatttagat
    14881 tacaaaggta ggaaattgag tgaacgactg aaagcggaaa gagataaaaa ttactttaat
    14941 ttcactcttt cagatgcatt tccaaataat cacgaaggat tcgggcatga ttataaaccg
    15001 gttctttgga tgcataaagc aaagtgatca ccggatgagg tttgataaga gtcagaaaat
    15061 cggcaacagc ctgagaagct tccagttcct tctgatacat tacgacaaaa tcattccagt
    15121 gacccggaat atcttcatga aaccatctgc gcagtgctgc ggaaggcgtt atatcttttg
    15181 cccagtaatc atatttcaac cattcttttt tgattccacg tggccagagt ttatctacca
    15241 gcacccgata tccgtcggtc tctgaaaagt cttcgtacac tcgctttatc ctaacttgca
    15301 ccatttccgt ttatatttag ttatcataag aataaaccga taaaacggaa aattgtttat
    15361 cgaaaaagcc aaaatcaacc taaggattcc tgcgcttttt taaattcgta aggagtcata
    15421 ccagtctttt tcttgaacat actgtacaga ataggcgtac tattaaatcc agcttcatca
    15481 gctatcgcac gaatggtata attgggatgt tgcttcaata actgaatcgc atagttaata
    15541 cgaagttcat taatataccc gttgaaatta gttccggtgt tttccttgat catccgggcg
    15601 aaacgcgcat tattcaaatg tacaatctga gccagatcct ctctcgacaa ttccggagac
    15661 agatataact gatcctgaac aacaatacga ttcagttctt tgaaaatttt cttattctca
    15721 tcctcttcct ccctactctc cactacttca tccggagata aatcgtcttt ttcggaaaag
    15781 ccagtttccg gttccaagtc taatggaaca gctatcggat cttccgcatc tccatctatg
    15841 aataattgtt tgttctctac ttttccagcc agtttctcat tgataaactt tgccagcatt
    15901 ttgtttttat atttaacaat aatcgtatga cgccaaatcc gccatagcac aaataaaatg
    15961 agacaagtga cacatcccaa aaaagcaagt gatatgtttc tgattcttaa ctgtaaagtc
    16021 tgttcggcaa tatattcttc ctgctcgtca gctttatgaa tagcatttaa ttccaaagcc
    16081 gcattctgtt tatccttgct gttaatacca tcaataatag aaataataga ctcacgtaat
    16141 gctgctactt tttcaaaatc cttcaagcct ttataagctt tcacctcttt ctgaaggata
    16201 ctaatatact gcaagttgac agtatcctgc tcttgcatca atttcttaaa atcctgacat
    16261 tgatcaacga ctttctgata ttgtttagac actagcagat aaggtatcgc ataagttttt
    16321 ccatccggtg tctgtgaatt ctctgttgac aaatattgtt gataatattt ttccgcctga
    16381 tcatactttc cttccagata gcagatatac gacatttttg catacaagta agtatattgc
    16441 agatcaagaa agccttttgt tttttccggt aatttagcta tatctttaag tagcttttcg
    16501 cgcttcaacc caacctccaa tgcttcttta ttacgggaat cattgagcag ataatccatt
    16561 ttcatcccat aaaagtatga aagcatagcc atttccaatt tggaacttgt accttgaagc
    16621 aatttgatag ctttgtcaaa atagtcatat gcctcctctt tgaaagacaa ttgccattta
    16681 ttttcaccaa tgcaaaacaa cagcttactt tcagcccctt tatccttttc tttttgtgct
    16741 agcttgatac catcaagagc atacctcata ctctctttat ggtcactcat aagcactgct
    16801 aattctgcca ggtcgacagt catggtcaac aagtgcttag gatctttctg agaaacggaa
    16861 tccagcaaat aagacttttt ggcatacaaa aaagccagtt tagtcatata catattacga
    16921 taaaccctgc tgcgtaattc atgtataata cgcagaggga tagtcttctt actttcagct
    16981 ccatccaaca aacttaaagc ccgttcaggt tctgccatat aaattcgact tatatactca
    17041 ctggtatata gcgaatcatt ctctatagtt ttgtcggcga aaaggagctg gttaaacaca
    17101 aacaaaaaca aacaaaaaca aataaccgag cgaatacttt tcattataat cccaatgatt
    17161 ttactcccca aaagtaaaac atagtttcat aaaatgcaag aattgaacat atttgaatga
    17221 actaaaataa gaaaagttag tgattataaa agtcaggagc catcaagttt tccccaccaa
    17281 ccacatacaa taaaatacta aaaatcaagc atatgtcaca tacataaaac aaaacatctc
    17341 aacatataaa taaactgccg attctattaa tgaatctgca taagatcaga gcagcacatg
    17401 aaaaatcgaa ccgaccagtc taaataaaca ccagacaatt attaacccgc cacactcatc
    17461 agagcaaaac aacacaaaaa cagaaaatca aaaaagagaa acacatactg taataagaaa
    17521 gattataatc ccaacgcttt atcaaaccgt tgctccatac atgcactcaa atccgtcgtt
    17581 acaaactttc ctttatagaa aagagaaaag atagtagcag gtgtaggtgc attttgtgct
    17641 tgtgccatcg tttccaatct gactatcttc aatggaatac ctttgttctc agtcacactc
    17701 actaaagaat tacggacatg aaactctgca aacggacaac gatgtgtata ataaacgact
    17761 acaccttctt tttcctcaca ttctccactt gatactgttc cattgaatga cggatcagga
    17821 gctgccggat ttatcttcaa agccaaaaga ctgaaaccat agggtagttt ttctatcgtc
    17881 tcaaacccct gacgtaataa ccatttcgca tcacccataa aatgaaattt agaggtaccg
    17941 accacagtca ccaagccatc cctaccctgt gctttggcat cctcgacagc agactgtaat
    18001 agtgctttgc catgcccgca tcctttatat tttcctgaaa cccaaaaaca gtttatcatt
    18061 aaatagttag gtgcattaac cggaacccaa gctttttcgg caggcccata ttctataaat
    18121 acttttgcac gttcgtcaag ccgtctgaaa acatagccat tctcaaactc atttttcagc
    18181 catgtctttt tcaactcata gctatccttg catttcttat cggagaaagc acagcaaata
    18241 tgttcttttt cgatattctc tttagtcaga gtgatatact tcgcttccat aatattctgt
    18301 ttattagtat ataaattccg gttgtccatt ttaactacag caaagataca caatcgaaag
    18361 taataaaaca ttgtccagtc tcgtcaaaat gacacagtag tacggattaa agttcggaaa
    18421 acagataagt aaataaacct gagtgacaaa cttatcaaag aacttattga ccactctgtg
    18481 gaagaagtga tcaaaaaaac tccctaagaa aaaacaggag gaatatcgca caatgattta
    18541 acataaagcg tgaaaccgct gactggtaac catacaaata tccggctttg ctgcaattca
    18601 caatagtaaa gccggatatt taactgtcaa aagcatatat cccatatacc acaagctctt
    18661 tccaatgcta ctagtgaagc ggcatatcct ttcattgttt ccagatactc ctgttgcact
    18721 tcattataag tacgctgggc aaccagtaca tcaagaatac tcgtttctcc ccgtttgtat
    18781 ttatatacca ttccgtcgag caccttctgc gagtcttcaa gtacaccggc tttatattga
    18841 gctatctttt tcttttcagc ctcatagttg aaccaggcct gggttatctc tgcctgtatc
    18901 tgcaattcca tatctctttc cattatctcc gattgggcaa tccgaaactt tgcagctttt
    18961 acagctcctt tatttatatt cgagaatgtc agaggaacag atacaccggc agtagcagaa
    19021 cgggacggag gaagaaagcc gttccagttt ctttcataag aaacagatac tccgatatcg
    19081 ggtctgcgtt ccgctctcgt cagtttatat tcccgggtag taacttcagt acttttttga
    19141 gcaacaagca ggtcgatgcg attatccagt cccgctttga ccaaatcaga cagagcaaag
    19201 tccctgctta gctcttccca atttcccaaa gggatatgaa gcgtatcagc actcatcccc
    19261 atgtgtttat tcaacaaaac caaagcggaa tgataagccg cctcctgact gtaaacagta
    19321 ttaagcaagg tgacagtttc cagttttgac tgccggacat cattctccgt aatctctccc
    19381 gaaacatagc gtaaactatc tgactgactc agctgataca tatactcata agaacttttc
    19441 tgtacttcaa gtaattcgcg ctgaagaatt gcttctagaa aaaggtcggc agcctccgcc
    19501 ctcaaatcct gaaagccctg ttgcaggacc agtttctcca attctgcctg agtccgcgcc
    19561 aacttaatac gtgctcccct tttatttccc atttctaatg aataggaaac tcccaacgag
    19621 aaagtctcat tacctgcttc aaattccaac tccgggtccg gaaagatttt ccgggcaatt
    19681 acttccgcat cagcaatact cacattgagt ttttcggcta aataactcag gttctttttc
    19741 gctacccgat tcagatattc ttcgaaagaa atagactgcc ccagctttat ttcaggcatt
    19801 tgcgcaaaag ccggaatgag tacggcttcc accattaaca gcaagagcac tatattatat
    19861 cgtatattct ttttcatcgt tcttcttttt atttaaaaca ttgttctcaa ccagataata
    19921 gaaaaccgga agcagaaaca tagaaataag ggttgaaaac atcaatccat acacaatcac
    19981 tgttgccagc ggacgctgta catcactacc gattccagtt gccaacgaag ccgggaaaag
    20041 tccgagtatc gtagtgaccg aagtcatcag aataggtcgg aaacgctggc gtgccccttc
    20101 tatgaccgat ttccggagtt ccattcctcc cctgcgcagc ccattgacct gcgataccat
    20161 gataattcca ttctgtatgg aaagcccgaa catcgctata aatcctacgg cagaagatac
    20221 attcagcgtc ataccacgca cattaagagc aagcatacct ccgaaaagtg ccagaggaac
    20281 aatagccaat accagtcctg cctgccggaa cttcccgaac gtgacataaa gcagtataaa
    20341 catccccgtc agtgtcagcg gtataatgac agcaagacgt gtataagccc gtttttgatt
    20401 ttcgaaggcc cctccccatt tgatggtata tttattcttg tcataatgta ctttctcatt
    20461 gatcgtattc tgggcttcat tcagaaaaga tgtcaggtca cgaccgcgca aattcagctt
    20521 taccgtcaaa tggcgtctgt tcatttccct ggtaatcgta ctttcgccga cactcaatct
    20581 gacatcggca acctgagaaa gaggtatctt tgcaccggtg gaagaagtca acataagtcc
    20641 ggctattttc tccggagtat tccgcgcttc ctctttatac ttacaggtga tgccatactg
    20701 gcggtcaccc tgataaagtt gtgcgatagc tttacctccg acagccactt caatcagatc
    20761 cgctacatcg gatacattta atccgtaacg ggctatggca tcacgattca tactgatctg
    20821 taactgtggc aagggtggtt cctgatcaat atccagatca acagcccctc gcacagttcc
    20881 taatgccctg gttatttctt cggcaatacg acgtgtttca cgaaaatctt cgccatatac
    20941 tttcaccacc agttcactat gggccccggc tatcttatcc atcaccccgt ctatcatagg
    21001 ttggctaaat cctactttaa aaccgggaag taacttatat tcttcttcca gttcatgaat
    21061 caaatccttt ttagtttttc ctttcggcca ttcatcataa ggcttaatac cgatggacac
    21121 ttcaaaatgt gaaggggtga acggatcagt tccgtcgtca ttccttcccg cctgtaccat
    21181 aatataagtt acttcggaat acttcatcgt acgggcacgc aaagtatcgg ataactcccg
    21241 tgacttttct acggaaattc cgggtggcag attaacctgt aaccatatcg aaccttcatc
    21301 cagctccgga aggaagtctt ttcctacgac aacactcaac acgatccccg ctgtcagaat
    21361 cagtcctgat ggaatgatgg cttttaaggg agcttccaga aatcctgtaa tggtacgaat
    21421 gtatttatcc tttagtctgt ccagccattt attcttatat attttatgtg gtttacgata
    21481 gatggcatag gcaagtcccg gaatcaataa gagcgcaacc aacagtgctc caatcattgc
    21541 atagctcatc gtaaatgcca ttggagtaaa aagtttgcgt tcaacacgtt caaaggcaaa
    21601 cagcggaagg tatgccgtaa taatgacaat ggttgagaaa agaataggcc gacccacttc
    21661 tttggcgcgt tgcgccatgc ttttttcttc gagatattgt ttgggattat cctcacgttt
    21721 cttaaggatc gtttccagca taacgatagc gccgtccaca ataataccaa aatcaatagc
    21781 accaagcgac agaaggttag ccggaatatc cgtcagatgc ataagaataa aagcgataag
    21841 caatgacaca ggaatcgtta tagataccaa taatgcacca cgccagttgc ctagaaacag
    21901 aataagcaca agaaccacca aagccatacc catcagcaag gtatgggata cggtactcaa
    21961 agtagtatcc accaagttgg tacgatccag aaaagtatgt atcctcactc cttccggcaa
    22021 tgtctcatta tttaactcat caactgccac atgaatatct tccagtactt tagacggatt
    22081 ctcatgtttc agaaggagta cgattccttc cagactctca gagtagttgc gggtacggtc
    22141 cgtatatccc agcactccct ttctttcaag atttccatac ttcaaagaac ctatatcatt
    22201 cagaaagaca ggaactccgg aagtagtact cactacaata tgtcccaaat cgtccaaatt
    22261 tccgattaat ccaattcccc gtaccacata acccaagtca ccacgattca acacgcttcc
    22321 ccccacattg gcattgttat tctcaatggc ttcaacaacc tggctgagag ataaattata
    22381 ttgttccagt ttggacggat ctacttcaac ctggaactga gtagtgatcc caccgaaatt
    22441 ggttacatca gccactcccg acacttcctt gatacgggga ataattaccc agttctgaag
    22501 gtcggttaat tcgcgtaatg agtgctggtc actttctatg atataacggt acacttctcc
    22561 tacgggagat gtcagcggat caagtcccgg aacagctcca taaggcagtt ctacttcatt
    22621 caatctttcc tgtacgcgct ggcggctcca gtagtcctct gtcccgtcct taaagacaat
    22681 ggtaatcatt gacagcccga atgtactctt actccgcatg acgtgcatac cgggcagccc
    22741 attaatagcg cgttccaaag gaatggttat ctgctgttcc acttcctccg cagccagtcc
    22801 gggaacttga gtgaccacct gggaagtgac atctgcaata tccggatatg cttctatcga
    22861 aagctgtttc catgagtaat atccaaagat acacatcatc acaaacaggc aaagcattac
    22921 ccatcttttt tgtataattg aaagcattaa ttccttcttc ataatttctt actttaaata
    22981 atatcctcct tcactgatta tcttatctcc gggacgcaat ccttcgctga tcaccgctat
    23041 tccgttttct gttgtctcca ctgtcaccga cgtccgtacg aaaaccaacg gagcaatctg
    23101 cacaaataca tagctatcct tttcgccctg cagtaacgct ttctccggga tttgaatttg
    23161 tctgaccgga acactcagaa agtggacagt agtgtacatt cccagcttca gatgtccgtt
    23221 caaattatca cagatcgaaa gtacctgaat ggaccgggtt tcctcgtcta cctcctcctc
    23281 tacatgatac acattgcctt taataac
//
