LOCUS       gnlProkkaLMFPGLLE_32   12538 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMFPGLLE_32.
ACCESSION   gnlProkkaLMFPGLLE_32
VERSION     gnlProkkaLMFPGLLE_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:03:25
            Original ID  :: gnl|Prokka|LMFPGLLE_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12538
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12538
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2190:2538]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2191..2538
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12538
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12538
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             758..2146
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             2191..2538
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_2"
                     /sec_met_domain="PF05402 (E-value: 8e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 3.4e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(2528..2815)
                     /locus_tag="ctg32_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(2837..3901)
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRDK
                     EEKTFTVRLTPDKEFENEVAFRFSKKLGVVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMDGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREEGK"
     CDS             complement(3975..5054)
                     /locus_tag="ctg32_5"
                     /transl_table=11
                     /translation="MKYINASPAMVVSIDIPSGLMGEENTFNVKSNIIRADVTFSLQLP
                     KLAFLFAENTEFVGEWELLDIQLSEEGIEETETNYEMLEIEEIRSLIKPRQQFAHKGNF
                     GHALLIAGSKGMAGASVLAARACLRSGVGLLTVHAPLCNNDILQTSAPEAMVETDVSET
                     CFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQLEHCQTPTVVDADALNILANHRHTLT
                     HLPKGSILTPHPKELERLVGKCQDSYERLMKACELAHTAKVHIILKGAYSAIITPEGKC
                     YFNQTGNPGMATGGSGDVLTGVILALLAQGYPAEDAAKIGTYIHGLAGDIAQKKQGMIG
                     LIASDIVTCLPTAWRLVSE"
     CDS             5121..5408
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MLRCQCGRYELGADFMESYFFHHLYQFFVGLAVGRKFAFRVEEIY
                     FDLVSFFRHHAGDGEGVSAIIARSGKDGDRCFRIPSVGDGFSQRLCGTLH"
     CDS             6223..6372
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MFTLCHELGLTFEDVAIAIGWLARENKILLRKKEGMLYASIENVE
                     FTFG"
     CDS             6565..8109
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 51.3; E-value: 1.1e-15)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWMMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     GDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIGAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             8151..8687
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             8721..9290
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             9303..10469
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             10493..11278
                     /locus_tag="ctg32_12"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQIPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHSGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             11318..11983
                     /locus_tag="ctg32_13"
                     /transl_table=11
                     /translation="MFEIKVSQEIKNACPVFAGAAVYAAVKNTAYCDGLWKEINTFTED
                     LTTTTQMADIKLQPVIAATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGKHLELGIGKAEEPFEGIGRGILNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDVGTTHILAIVNGYNGKEGLKEAAEMIQSLLRDYAGSDGGELIYFE"
ORIGIN
        1 atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac gctaattcaa
       61 aataactaaa aatgtactta ttattcatta tcttaatggt gattgcagcc ttgctgatgt
      121 gcttcatcgt gctgattcag aattcaaaag gaggcggact tgcttctggt ttttcttcat
      181 caaacgctat catgggcgtg cgcaagacta cagattttct ggaaaaagca acttggggtc
      241 tggctatctt catggttgtg atgagcgttg ctactgctta cgttgttcct tcttcttctg
      301 cagctaaaga tgtattgttg gaacaagcac agaaagaaca acaaaccaat ccgtataata
      361 tgcctaccgg tactgctgct cctcagacag acgctactgc tcctgcagag tctgcaccag
      421 caacagaagc tccggctact gaaactcctg ctcctgcagc agaataattc agtgacagga
      481 tattcggttt aaacttattg agtgaacggg ctttttgacc cgttctcttc attataggcg
      541 cgaattacgc gaattacaag agattctaat agaattgtgt aatacgtgtg gttcgcgcct
      601 atctttatta ttgggtccgg tctgctcttc ttcatacagg aatatccggt cagatgtcct
      661 ttttcttata aaatgttctc cttttttagt aaaacaaatg ataattagtt aactttgttg
      721 cccgttacga gattattaac tccttttaaa tattacaatg acagaacaat tgaaacaaaa
      781 gctgaatgac tccgcagtgc tgcgttggag tgttctagca ttagtcgctt ttaccatgtt
      841 gtgcggctac ttcctcacag acgttatgtc tcctctgaaa cccatgcttg aaaaagaact
      901 tctctgggac agtttagatt acggtttttt caccagtgct tatggctggt ttaatgtatt
      961 cctgctgatg ctcatctttg gtggtatcat tctggataag atgggagtac gcttcaccgg
     1021 aatgggtgcc tgtttattga tggtgtttgg ttgtggattg aaatattatg ctattactac
     1081 tactttcccg gaaggtgcga tgcttttcgg attcaagatg caagtcacat tggctgcatt
     1141 gggctatgct attttcggtg taggagtcga aattgcgggt atcaccgttt cgaagattat
     1201 cgtgaagtgg tttaaaggca aagagatggc tctcgctatg ggactggaaa tggcgaccgc
     1261 gcgtattgga acaactttgg ccatggtgct taccgttcct ttggcagact tcttcgggtc
     1321 tacggatgag agcggcgtat tccataccaa tattcccgct ccgattctgt tctgtctcgt
     1381 catgctgtgc gtaggtacca tcgcattctt catctatact ttctatgata agaaactgga
     1441 tgcttcactg gatgcggaag gactggaacc ggaagaacct ttccgcatga aagacatcgt
     1501 atatatcatt accaacaaag gattctggct gatcgcatta ctgtgcgtat tgttctattc
     1561 ggctgtattc cccttcatca agtatgcggc tgatttgatg gtacagaagt acaatgtaga
     1621 tccgaaactt gcgggaacga ttcccggatt gctgccgatt ggcgcgatca tcctgacacc
     1681 gttgttcggg tcattgtatg accgtatcgg taagggagcc acgctgatgg tgatcgggtc
     1741 ggtgatgctg attttcgtac acactatgtt cgctcttcct attctgaata tctggtggtt
     1801 tgcaacggtg atcatgatta ttctgggatt tgctttctca ttggttcctt cggcaatgtg
     1861 gccttcggtt ccgaagatta ttccggagaa acagttggga acggcttatg cgttgatctt
     1921 ttgggtacag aactggggat tgatgggcgt gcctttgctg attggatggg tgttgaattc
     1981 ttattgcaaa ggtccggttg tagatggtgc acagacttat gattatacct tgccgatggc
     2041 tatttttgct atgttcggtg tacttgccct gattgttgcc ttgatgctga aagcagaaaa
     2101 caagaagaaa ggctacggac tggaagaagc aaatattcag aaataatcac agtatatatt
     2161 ctatctgaaa agatataaaa gagaaaagat atggctacga aagagaaaat aaacctcctg
     2221 gaggtgatcc cttgtcgtaa cgaacatatt aaagctgaac aggaagggga gactattgtg
     2281 ctctccttcc ctcgttttaa acgttcgtgg atgagtcgtt atttattgcc gaaaggaatg
     2341 tccaaagata ttcatgtgcg tctggaagaa cacggtacgg ctgtatggaa cctgatagac
     2401 gggcagcgga cggttcgtga gattatagaa aaactcgcag accactttca gcatgaagca
     2461 ggctacgagt ctcgtgtatc tacctatctt tcccaattac agaaagacgg atttattaaa
     2521 tggataatta tccattaaaa aagattgccc acaggaggac agcgcatcct atcagtacgc
     2581 ccataatgat gagcgttccc catacgaaat agctgttatc tttttctttt ttcttttccg
     2641 aatccttgat gatgcgttcc atctcttccg gagtcgtatc cggcagaaga taagggtcgt
     2701 tgtttcttct aagtcgccct aacttgtcat ttctccgttc acggcgtaag cgggaggctt
     2761 ctttgccgtc tttcagccga cgtatcatgt cgagcatatg tccttcgcca cccatcgttt
     2821 tgttttttta gaggttttat ttgccttctt ctctatctac tttcagtagt ccaccggtca
     2881 ccggatcaaa gtaaactttg atggtcgagt tcttgttgaa taataccgga gcaaggtatt
     2941 ctatgatacc gaactgagta acaggtattt ctccttcata caatttcttt ttgccgtccg
     3001 tcagcgtcac cattgcctgt cccggtacgt tataagcaat tccatccatc tctttcttct
     3061 ttttcccgtc ctcttgcgga atcttcaccg ttttcaggtc tttcagactg atgtagaatg
     3121 gagtgcctgc caaatcgttg ttggcaacta cacccagctt ctttgaaaag cggaaagcta
     3181 cctcattctc gaattcttta tccggagtga ggcggacagt aaatgtcttt tcttctttat
     3241 cgcggactcc cgaaaacatc tcggtcatgg cctcttcctg aagattcagg ttgtcgagca
     3301 tgattttgag ctgtgcgccg tccgacggca tattatctgc ttgtccgcgc aataatgcgt
     3361 ttttactttc gcggatatta tagatttcct ttgctaccag ttcggccatc ttggcggtag
     3421 aacttgccat cagaatttct tctgtgagga agtcgcgggg attggctttt cgttggggag
     3481 caacggcatt gtttgctgca ttctttgcat tgttgctgct gtaggggacg ttgattgatt
     3541 tgataagacc ctcttcagtc agttccataa gaggagctac ggttttgtct ttcagtttga
     3601 cgaaataagt ggcttcgctg tttggtacac ctacaggttt caccttgacg ctgttcaatt
     3661 cccagtattc ttcgggttcg gcagagacgt tggtcagtct caggtagcgg tcggcgtatt
     3721 tgctgaattc acccggctta tagttgactt tatttgcttt tatttctatt tctatctggg
     3781 ttttggggag ggcgtacact actccgtagt cttttcctcg tgtcactcct gtcagcactt
     3841 cggtctgcgc ataggcggaa gttgccatta gtagtcctgt tgctatgatt aactttttca
     3901 tattcggttc tttttagctg attttgaaaa acaaagttaa tgaagttatt gaataaaccg
     3961 taagttctta acttttattc gcttacaagt cgccatgccg tcggcagaca ggtcacgata
     4021 tcacttgcga ttaatccgat catgccctgt tttttctggg cgatgtctcc ggccaatccg
     4081 tgaatgtaag taccgatctt tgcggcatcc tcggcaggat agccttgcgc aaggagtgca
     4141 aggattactc ctgtcagtac atctccgctg cctcctgttg ccataccggg attaccggtc
     4201 tggttgaagt aacatttgcc ttcgggggtg ataatggcgg aataagctcc cttcagaatg
     4261 atatgtactt tggcagtgtg agccagttcg caggctttca tcagtcgttc gtatgagtcc
     4321 tgacatttgc cgaccagacg ttccagttct ttcgggtgag gggtgaggat ggaacctttc
     4381 ggcagatggg tgagcgtatg tcggtgattg gccagaatat tgagcgcgtc ggcatccact
     4441 acggtcggag tctgacaatg ttccagttgt tctatcaagg cagcttccgt ttcctcgctg
     4501 cgaccgagtc ccggaccgat gccgacagct tgataatcgt ccgtatcggt aggtacggca
     4561 aagcatgttt cgctgacatc tgtttctacc atggcttcgg gggcggacgt ttgcagaata
     4621 tcgttgttgc ataacggcgc gtgtacggtc agcagaccta ctcccgagcg cagacaggca
     4681 cgggcggcca gtaccgatgc acctgccatt cctttcgaac cggctatcag cagggcatgt
     4741 ccgaagtttc ctttatgggc gaattgctgg cgtggcttga tcagcgaacg gatttcttcg
     4801 atttccagca tttcgtagtt tgtttcagtc tcttcgattc cttcttcgct cagctggatg
     4861 tccaataatt cccattcgcc aacaaattct gtattttcgg caaagaggaa ggccagttta
     4921 ggaagttgca ggctgaaagt gacatccgca cggataatat tgctttttac attgaatgta
     4981 ttttcttctc ccatcagccc ggaagggatg tcgatggaga ctaccatggc gggagaggca
     5041 ttgatatatt tcacaacggc agcgaatcct ccgctcaatg gtttgttgag tccggaaccg
     5101 aataatccgt cgatcacgag atgctccgat gtcagtgtgg gaggtacgaa ctgggtgctg
     5161 atttcatgga aagttacttc ttccatcatc tctaccagtt ctttgttggt ctggcagtcg
     5221 ggcgaaagtt cgcctttcgt gttgaagaga tatacttcga tcttgtatcc tttttccgcc
     5281 atcatgcggg cgacggcgag ggcgtctccg ccattattgc ccggtccggc aaagatggtg
     5341 acaggtgttt ccggattcca tctgttggtg atggctttag tcagcgcctg tgcggcacgc
     5401 tccattaaat ctatggatgc aatcggttca tgttcaatgg tataggcatc taacttctta
     5461 atgctgctgc ttggaaatat tttcattgcg atattctttt agttttcgac gcacaaactt
     5521 acacaaaaac tctgaattaa tcctttattc cggttggttt tcggctttag ataaagtggc
     5581 aaattgaaaa atgcagggga aatcagaagt tatcttgggg tggctttgtc ctgtctgtct
     5641 gtgattcctc agttgggggg cggatatttc tctgcaaagg tacgggcatt cttcagataa
     5701 gatgcggaga cttttcggct aagatgcagg cattcttctc ttaaagtgcc tttttcttta
     5761 gttgctcacg gccgtgacaa gacttcgcca cgaccgtgag caatgctaat cacggtcgtg
     5821 aacaatgctt gtcacgaccg tggtcagtta atgatatcgg tgctttgatg taactattct
     5881 actgctttct ccttaatctt ccgatacttt gagagatagt tacgccttct ccggcctgct
     5941 atagaactgc ttcctttatg agtgtcttcg gcgtttggaa taaagctgtc agtagatatg
     6001 gtacaatata aacagctaat gccttgatta tttgcttttt tcgaaaaaaa tgatatcttt
     6061 gtagtgcagt aatgtgcttt acgttattct cctgtgctca caatgtttag attataaata
     6121 taaattgttt aatcttctaa agtttgcatg atggaaaaga aaagaattgg ctcaaatgcc
     6181 gggaaagtat ggcgcatctt aaatgaaaag ggcgaacagt ctatgttcac cttgtgccat
     6241 gagttaggtt tgacgttcga ggatgtagcg attgctatcg gctggttggc aagggaaaat
     6301 aaaatcctgc ttagaaaaaa agaaggaatg ctctatgcca gtattgagaa tgttgaattt
     6361 acttttggat aaatggcgac tgacccacat ttaaggggaa tatccacttg attatttaca
     6421 ctgttgaaaa cataataagg tgggtaactg agacttcttg cacgccatcc tgtatttttc
     6481 tattccataa gaatcttctt ttttgaggca tttaatctac tttttagtac ctttgcaccc
     6541 cataaactac taaacacata attcatgagt tcattgaaag ggcacccgaa aggcctttac
     6601 ctaattttcg caacgagcac ggcagaacgt ttcagttact acggtatgcg tgccatcttt
     6661 atcctctttc tgacgcaggc attgcttttt gataaagaag cggcagcctc tatctacggt
     6721 agctacaccg gactggtcta tctgactccg ttgatcggcg gatacattgc cgataaatat
     6781 tggggcatcc gtcgttcggt gttttgggga gcggtgatga tggcagtcgg tcagttcctg
     6841 atgtttatga gtgcctcttc actaaacaat acagaccttg cccactggat gatgtatggt
     6901 gggctcggat tcatgatttt aggtaacggt tgctttaagc ctaccgtttc ttcgcttgtc
     6961 gggcaattat atgaaccggg ggataaacgg ttggatgctg catacaccat tttctatatg
     7021 ggtgttaatg tcggttcttt cgctgctcct ttgatttgcg gtttcttggg agacacaggt
     7081 aatccgcagg actttaaatg gggattcctc gcatccggaa tcatgacgct gttcactgtt
     7141 gtcctctttg aaactcagaa gaataaatac cttttctctc cttccggtga accgattggt
     7201 atcgtccccg atgccagacg tgaaaaaaag ggggataaag ccgaacatat ttcacatccg
     7261 aagatggaca aacgtaccaa agtacgtaat atcatcatca ttactgccct tacagttgcc
     7321 ttaatagcct tttttagcta tgcctttagc gatgactgga ttagtgtggg tatctttacg
     7381 gcttgtattg tctttccagt gctcattctg ctggatggtt cattgaccaa agtagaacgt
     7441 agccgtattt tcgtaatcta tatcggagct ttcttcgtca ttttcttctg ggcagcttac
     7501 gagcaggcag gagcttctct gacattattc gcttccgaac agactgaccg cagcattttc
     7561 ggctgggaga tgccggcttc gtggttccag tcattcaatc cgctttttgt agtgatcctt
     7621 gcctatatta tgcccggtat atggagcttt ctgaataagc gaaacatgga accggcttcc
     7681 cctaccaagc aggcaatcgg tctgttgctg ctttctcttg gttatctctt catctgtttt
     7741 ggagtgaaag atgctattcc gggagtaaag gtgagcatga tctggctgac aggactttat
     7801 tttattcata caatgggaga aatcgctctg tcacctatcg ggctttctat ggttaataag
     7861 ttgagtccgt tacgtttcgc ctccttgatg atggggatct ggtatctttc taccgccacc
     7921 gcaaataaat ttgcaggtat gctgagcggt ctctatcccg aagacggaaa agtgaaatca
     7981 atccttggtt atcagattgc taccatgtac gacttcttca tgctgttcgt cattatgtcc
     8041 ggtgttgcct cactgattct gttccttctc tcgaagaaat tacagaagat gatgcacggg
     8101 gtagaataaa aaattgtatt tttgcgacaa cttttttaaa atggccggtt atggatacca
     8161 tacagataaa agacaagcaa tttactgttt ccattaagga acaggatatt caaaaagaag
     8221 tgattcgcgt agcgaacgaa atcaatcgtg atttggcagg taagaatccg ctcttcctca
     8281 gtgtgttgaa cggctcgttc atgtttaccg ccgacttgct gaagcatatt acgattccgt
     8341 gcgaaatttc attcgtgaag ttggcatctt atcagggggt gacttccacc ggagtaatta
     8401 aagaagtgat cgggctgaat gaagacattg ccggacgtac ggtagtgatc gtagaagata
     8461 ttgtagatac cggactgacg atgcagcgtc tgctggatac actgggcaca cgcaaccccg
     8521 aagcgattca tatcgcctct ttgctggtga aaccggaaaa gctgaaggtc aatctgaaca
     8581 tagaatacgt agcgatggaa ataccgaatg attttatcgt tggctacgga ttggattatg
     8641 atggtttcgg acgcaattat cccgatattt atactgtagt agattaaatt caaatacaaa
     8701 ttaattttta ggttaaaaag atgttgaaca ttgtaatttt cggtgctccg ggttcaggaa
     8761 aaggaacgca gagcgaacgt attgtagaaa agtatggaat caaccacatc tcgacaggag
     8821 atgtattgcg tgcagaaatc aagaacggca cggaactggg caaaactgct aaaggttaca
     8881 tcgaccaggg gcagttgatt ccggatgaat tgatgattga tattctggca agcgtattcg
     8941 atagcttcaa agacagcaaa ggtgtaattt tcgacggttt cccaagaaca attgcacagg
     9001 cggaagcatt aaagaagatg ttggcggaaa gaggacagga tgtttctgta atgttggatc
     9061 tcgaagttcc ggaagatgaa ctgatggtac gtctgatcaa acgtggcaaa gactccggtc
     9121 gtgccgacga caacgaagaa acaatcaaaa aacgtctgca tgtatatcat tcacagacat
     9181 ctccgctgat cgactggtac aagaacgaaa agaaatacca gcacatcaac ggtctgggta
     9241 ctatggatgg tatcttcgct gatatctgcg aagcggtaga caaattataa taaataaaaa
     9301 atatggctga atcgaatttt gttgattacg taaagatata ctgtcgctca ggcaagggcg
     9361 gaagaggctc tacgcacatg aggcgcgaga aatattgtcc taacggaggt cccgatgggg
     9421 gcgatggtgg aagaggaggc catattatct tgcgcggtaa ccgtaattac tggacattgc
     9481 ttcacttgaa gtatgaccgt catgcgatgg caggtcatgg cgaatcgggc agcaagaacc
     9541 gtagtttcgg aaaagacggt gcggataaag tgatcgaagt accctgcgga acggtagtgt
     9601 ataacgccga aaccggagaa tacctttgcg atgtgacgga cgacggacag gaagtgatct
     9661 tgctgaaagg cggtcgtggc ggtcagggaa acagtcattt caagacggct acccgtcagg
     9721 ctccgcgttt tgcgcagccg ggcgaaccga tgcaggaaat gacggtgatc atggagctga
     9781 aactgttggc agatgtagga ctggtaggtt tcccgaatgc gggaaagtct acgttacttt
     9841 ctgccatttc ggctgcgaaa ccgaagattg ccgattaccc gtttacgaca ctcgaaccga
     9901 atttgggaat tgtttcctat cgcgatggaa agtcattcgt gatggcggac ataccgggta
     9961 tcatcgaggg agccagtcag ggaaaaggat tgggactgcg gtttctgcgt catatcgagc
    10021 gtaactcgtt gctgttgttc atggttccgg cggatagcga tgatatccgc aaggagtatg
    10081 aagtattgct gaatgagttg cgtacgttca atcccgaaat gctggacaaa caacgtgtgc
    10141 tggctatcac gaagagcgat atgctcgatc aggagctgat ggacgagatt gaaccgacat
    10201 tgcccgaggg tgttccgcat atattcattt cttctgtttc cggtttggga atctcagtgt
    10261 tgaaagacat tctgtgggag gaactgaaca aggaaagtaa taagatagaa gacattgttc
    10321 accgtccgaa agacgtgacc cgtctgcagc aggaactcaa ggacatgggc gaggatgaag
    10381 aactcgacta tgaatatgag gaagacgctg acgacgacga tgatgatctc gactacgaat
    10441 acgaagaaga ggattgggaa gaaaaatgat ttcaatcaca agagataaaa gaatgttggg
    10501 gtatgagtcg ttaagctcat actccaacat ttctcatttt gtaactaccc ggcagggagg
    10561 atgcagcgag ggaaattatg cgtcattcaa ctgtacgcct tacagtggag acgaggcgga
    10621 aaaggtccgg cggaatcaga cgcttctgat ggaaggaatg tcgcagatac ccgaagaact
    10681 ggtgattcct gtgcagactc atgagacgaa ttgcctgctg atcggggatg cttatttatc
    10741 ggcttcgtct caacaacgac aggagatgct gcacggagtg gatgctttga ttacccgcga
    10801 gccgggatat tgtctttgta tttctactgc ggattgtgtt cctgtgttga tatatgataa
    10861 gaaacatagt gccatagctg ccattcattc cggatggaga gggacggtag catacatcgt
    10921 gcgtgatact ttgttgcgga tggaaaagga gtttggcaca agtggagaag atgtagttgc
    10981 ctgtatcggt ccgagtatct cattggcttc ttttgaagtg ggtgaggaag tgtacgaagc
    11041 atttcagaag aatggttttg atatgcctcg tatttctatc aggaaagagg aaaccggaaa
    11101 acatcatatc gacttgtggg aagcgaaccg gatgcaaatc cttgctttcg gtgtgccgtc
    11161 cggccaggtg gagcttgccc ggatatgtac gtatattcat cacgacgagt ttttctcggc
    11221 aaggcgtttg ggcattaagt ccggacggat tctgtcgggg atcatgattc ataaataata
    11281 gacttgaacg taagttgata taaacttgaa tagaagtatg tttgaaataa aagtatctca
    11341 ggaaataaag aacgcctgcc ctgtttttgc cggagcagcc gtatatgcag cagtgaagaa
    11401 tactgcttac tgcgatggac tttggaaaga aataaatact ttcacagaag acttgactac
    11461 caccacccaa atggcagaca ttaagttgca acctgtgatt gctgctaccc gtgaggctta
    11521 taagcgttgc ggaaaagatc cggggcgtta tcgtccgtcg gcagaagcgc tgcgccgtcg
    11581 cctgatgcgt ggcatccctt tgtatcagat tgatactttg gttgacctta tcaatctggt
    11641 ttctctccgt accggacatt ctatcggtgg cttcgatgcg gataagatac agggtaaaca
    11701 tcttgaactt ggcattggca aagcggaaga acctttcgaa ggtatcggtc ggggcatttt
    11761 gaacattgaa ggattgccgg tgtacagaga ttcttttgga ggaatcggga caccgacaag
    11821 cgaccacgaa cgtacgaaga tggatgtcgg gactactcat attctcgcga tagtcaacgg
    11881 gtataacgga aaagagggat taaaggaagc tgctgaaatg attcaatcct tactgaggga
    11941 ttatgccgga tcggatggcg gcgagcttat ctattttgaa taataaagga atacatgaag
    12001 aacatactta ttttattgac agtcctgctt ttaccaactc ttgcttatgc gcaaagtaaa
    12061 tcctcttttt cttctatgga ggtgaatcat gtacgggttg ctactcccgg actttttgcg
    12121 aaaagcaatc atatatatct gcatttggat tctttgcaag agcatgaata tgcttttccc
    12181 ttaccgggag ccaaagttat ttccgcttac ggaactcgcg gaggacattc gggagcagat
    12241 ataaagacgt gtgccaaaga tacgattcgt gctgcttttg atggagtcgt acgtatgtcg
    12301 aagccatatt atgcttacgg aaatttggtt gtagtccgtc atgcgaacgg gctggaaacg
    12361 atttacagtc ataacttcaa gaatttggta cagagcggag atacggtgaa agccggacaa
    12421 cctatcggac tgaccggacg taccggccgt gctactacgg agcatgtgca ttttgaaacc
    12481 cgcattaacg gtcagcattt taatccgaat cttattttca atctgaagga gggcacat
//
