LOCUS       c00668_gnlPro..         4083 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PICIGOPO_668.
ACCESSION   c00668_gnlPro..
VERSION     c00668_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:28:54
            Original ID  :: gnl|Prokka|PICIGOPO_668
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4083
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4083
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[151:4083]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      152..4083
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4083
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4083
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..104
                     /locus_tag="ctg668_1"
                     /transl_table=11
                     /translation="MTPVTRDRYVPKSLKAYASMVSSADKGAVRLID"
     CDS             152..1849
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg668_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-47, bitscore:
                     148.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRIVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGAFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             1868..2431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg668_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.7e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             2431..3174
                     /locus_tag="ctg668_4"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             3238..4083
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg668_5"
                     /sec_met_domain="IlvN (E-value: 9.4e-48, bitscore: 150.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.2e-29, bitscore: 90.2,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     P"
ORIGIN
        1 cgatgactcc cgtgacccgt gaccgttacg tgccgaagag cctgaaagca tacgccagca
       61 tggtaagctc tgccgataag ggagcagtga gattaataga ctgatccact tcattatcca
      121 ttatgaatca tccattatcc attaaagaac tatgagtaag gacttaataa caggcgcaga
      181 ggcaatgatg cgctctctgg aacatcaggg agtgactacc attttcggtt atcccggcgg
      241 gtccatcatg cctacgttcg atgccctgta cgaccatcaa aatacattga accatatctt
      301 ggttcgccat gaacagggag ctgcccatgc ggcacaaggc tacgcccgtg tatcgggtaa
      361 agtcggtgtt tgcttggtga caagcggccc cggagcaacc aatacgatca caggtattgc
      421 agatgcaatg atagacagta cgcctatcgt tgtcattgca ggacaggtgg gaacaggctt
      481 tcttggaaca gacgcttttc aggaagtcga tctcgtaggt atcactcagc caatcgctaa
      541 atggagctat cagattcgcc gtgccgaaga cgtagcctgg gcgatagcac gtgctttcta
      601 cattgccagt agtggtcgtc ccggtccggt ggtactcgac tttgccaaga atgcgcaggt
      661 tgaaaaaacg aaatacgagc cgacaaagca ggagtttatc cgcagctatg ttccggttcc
      721 cgatacagac gaagaatcgg taaaggctgc cgccgaactg atcaataacg ccgaacgccc
      781 gcttgtcttg gtaggacagg gagtggaact gggaagcgct caggaagaac tgcgtatctt
      841 tatcgaaaag gcggatatgc ccgcaggttg taccttgctc ggactttccg cattgcctac
      901 cgatcatccg ttgaataaag gaatgctggg tatgcacgga aatctgggac cgaatatcaa
      961 tactaacaaa tgtgatgtac tgattgctgt cggtatgcgt ttcgacgacc gtgtgaccgg
     1021 taatctggct acttacgcca aacaagcgaa agtgatccat tttgacattg atccggcgga
     1081 agtaaataag aatgtaaagg tagatattgc cgttttgggc gactgcaaaa agacgctggc
     1141 tgctgtgacc ggactgttga aaaagaaccg gcacaccgag tgggtcgata gtttcaagga
     1201 atatgaagcg gtagaggaag aaaaagtcat tcgtcctgaa cttcatcctg caacggattc
     1261 actgagtatg ggcgaagtgg tgcgtgcggt aagcgaagcg acccgtcacg aagccatatt
     1321 ggtgacagat gtaggtcaga atcagatgat ctctgcccgc tactttaaat ataccaggga
     1381 acgtagtatc gttacttcgg gtggactcgg cacgatgggt tttggccttc cggcagctat
     1441 cggagctact ttcggccgtc ctgaccgcat tgtatgtgta tttatgggtg acggcggact
     1501 gcaaatgaac attcaggaac tgggtacgat catggaacag aaagctccgg tgaagattat
     1561 ctgcctgaac aacaattatc tcggcaacgt gcgccaatgg caggctatgt tctttaatcg
     1621 ccgttattca tttactccga tgctgaatcc ggattacatg aaaatcgctt ccgcctacga
     1681 tattccttcc aaacgtgtct tttcacggga agaattgaaa gcggccatcg acgaaatgct
     1741 ctcgacagac ggggcgttcc tgctcgaagc ctgtgtggta gaagaaggca atgtcctccc
     1801 gatgacccct ccgggcggtt cagtcaatca gatgttgctg gaatgttaat ccttaattta
     1861 gaaagttatg agtgataaga cattatatac gattatagtt cattctgaaa atatagccgg
     1921 attgctgaat caggtgaccg ctgtatttac ccgtcggcaa ataaacatcg agagtttgaa
     1981 cgtttctgct tcttccatta aaggagtaca taaatatacg atcacagcgt ggactgataa
     2041 ggacactatt gaaaaggtgg tgaagcagat cgaaaagaag attgatgtga ttcaggcgca
     2101 ctattttact gaagacgaga tttatttcca tgagatagcc ttatataagg tatctactcc
     2161 tgcttttcag gagactccgg aagcatctaa agtgatccgc agatataatg cccgcattgt
     2221 agaggtgaat ccggtattct ctatcgtcga gaagaacggc atgagtgaag agattacttc
     2281 cctttacgaa gaacttcggg ctttgaaatg tgtgctgcaa tttgtccgtt cgggtcgtgt
     2341 ggctattact accagctgtt tcgaacgtgt gaatgagttc ctggacggac aggaagcgaa
     2401 gtataagcaa agtaaaaagg aacaggagta atgagtgaag aaaataaaat agggacttat
     2461 cagtttgtgg cagagccgtt tcacgtagat tttaacggcc gcctgaccat gggcgtgctg
     2521 ggaaatcatc tgttgaattg cgcaggtttt catgccagcg accgtggatt tggtattgct
     2581 acgctgaacg aggacaatta cacatgggtg ctttcccgcc tggctatcga gctggatgag
     2641 atgccttacc agtacgagaa gttctcggtt cagacatggg tggagaatgt ctatcgtctc
     2701 tttaccgacc gtaactttgc cgtcattgac aaggatggaa agaagatcgg ctatgcccgt
     2761 tccgtatggg cgatgatcaa tctgaatacc cgtaagcctg ccgatctgtt ggcattgcat
     2821 ggaggaagca tcgtcgatta tatatgcgat gaaccctgcc cgatagaaaa gccttcgcgt
     2881 atcaaggtga caagcaatca gcctgttgcg acgctgacgg caaaatacag tgatatcgat
     2941 attaacggac acgtaaacag tattcgttat atcgagcaca tacttgactt gtttccgata
     3001 gaactgtatc agacgaaacg tatccgccgg tttgaaatgg cgtatgtggc tgaaagttat
     3061 ttcggagatg aactctcttt cttctgtgat gaggtgagtg aaaacgagtt tcatgtagag
     3121 gtgaagaaaa acggcagcga ggtagtatgc cgttccaaag tgatatttga ataatataga
     3181 gtataaaatc aattaataac agatggcgca agtcatcaaa acaaaaaaac aaaaaaaatg
     3241 gcacagttga attttggcgg aactgtagaa aatgtagtta tccgtgatga atttccattg
     3301 gaaaaagctc gtgaagtatt gaaaaatgaa acaatcgctg taatcggtta tggcgtacaa
     3361 ggtcccggac aggctctgaa ccttcgtgat aacggtttca atgtaatcgt tggtcaacgc
     3421 cagggaaaga catatgacaa agcggttgct gacggatggg ttccgggtga aactttgttc
     3481 ggtattgaag aagcttgcga aaaaggtacg atcattatgt gcctgttgtc tgatgcagca
     3541 gtaatgtctg tatggcctac tatcaagcct tacctgactg caggaaaagc tctttatttc
     3601 tctcatggtt ttgctattac atggagtgac cgcacaggtg tagttcctcc tgcagatatc
     3661 gacgtaatca tggttgctcc taaaggttcg ggtacatcct tgcgtactat gttccttgaa
     3721 ggtcgcgggt tgaactcttc atacgctatc tatcaggatg caacaggcaa cgctatggac
     3781 agaacaatcg cattgggtat cggtatcggt tcaggttatt tgttcgaaac aactttcatc
     3841 cgcgaagcta cttccgacct gacaggcgaa cgtggttcat tgatgggagc tatccagggt
     3901 ctgttgctgg cacaatacga agtgttgcgt gaaaacggtc acactccttc cgaagcattc
     3961 aacgaaactg tagaagagct gactcagtca ttgatgccgt tgtttgcaaa gaacggtatg
     4021 gactggatgt atgctaactg ctctactaca gctcaacgtg gtgctctcga ctggatgggc
     4081 ccc
//
