LOCUS       gnlProkkaMJBHDAKO_28   12368 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MJBHDAKO_28.
ACCESSION   gnlProkkaMJBHDAKO_28
VERSION     gnlProkkaMJBHDAKO_28
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:32:07
            Original ID  :: gnl|Prokka|MJBHDAKO_28
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12368
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12368
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2014:2368]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2015..2368
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12368
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12368
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             69..449
                     /locus_tag="ctg28_1"
                     /transl_table=11
                     /translation="MYLLLVILMVIAAILMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWGLAAFMVVMSIATAYVVPTSSSKTQDVIMEQAQQEEQTNPYNLPVGTTA
                     PKTDAAAPVEAPATETPATPAN"
     CDS             746..2008
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 82.1; E-value: 5.1e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_2"
                     /transl_table=11
                     /translation="MLEKELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFT
                     GMGACILMVLGCGLKYYAISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIAGITVSK
                     IIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNIPMPILL
                     CLIMLCIGTIAFFIYTFYDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWLIALLCV
                     LFYSAVFPFIKYATDLMVQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRIGKGATL
                     MIIGAVMLIGVHTLFALPILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIPEKQLGT
                     AYALIFWVQNWGLMGVPLLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGVLALIVA
                     LMLKAEDKKKGYGLQEANIKK"
     CDS             2015..2368
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_3"
                     /sec_met_domain="PF05402 (E-value: 6.4e-17, bitscore: 53.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 9e-10, bitscore: 29.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSADIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(2503..3558)
                     /locus_tag="ctg28_4"
                     /transl_table=11
                     /translation="MKKLIILTGLLLSTSAYAQTEVTAGVTRGKDYGVTYALPKTAINI
                     EVKVNKVTYTPGEFSKYADRYLRLTDVSGEPQEYWELVSVKAKSVGIPDSEHTYFVKLK
                     DKTVAPLIELTEDGIVKSINVPLSPKKSAPMQPATTQKKKINPRDFLTEEILMAGSTAK
                     MAELVAKEIYNIRESKNALVRGQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKD
                     EKIFNIRLTPDKEMDNEVAFRFSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKK
                     VDGIAYNVPGKAQVTLTEGKKQWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTG
                     GLIKVDREEGE"
     CDS             complement(3631..4941)
                     /locus_tag="ctg28_5"
                     /transl_table=11
                     /translation="MLAEKEYKVEAYLFNPKGELSADCQTNKELVEMMDNVKFSEVSTQ
                     FVPPALTMDHLVVDGLFGSGLNKPLSGGFAAVVKYINASPATVVAIDIPSGLMGEENTF
                     NVKANIIRAQLTLSLQLPKLAFLFAENSEFIGEWKLLDINLSREAIEETESNYALLEAE
                     EIHALIKPRNTFSHKGNFGHALLIAGSYGMAGASILAARACMRSGVGLLTVHAPIRNND
                     ILQISVPEAIIESDASDTYFACPTDTDDYQAVGIGPGIGRSEETEAALLEQLSGCQTPL
                     VLDADALNILANHRHALTTLPKGSILTPHPKELERMVGKCQNSYERLMKACELARTAKV
                     HIILKGAYSAIITPSGKCYFNSTGNPGMATAGSGDVLTGVVLALLAQGYPAEEAAKIGT
                     YVHGLAGDFARKKQGVISMTAGDIISNLPLAWRLVSE"
     CDS             complement(5186..6526)
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="MNNVQQVKTYSQRKISDFLFILWAGGAALLSYSLVYALRKPYTAA
                     GFDGLEAFGMDYKVVVTIAQILGYVLSKFIGIKLISELKRENRMKFILISIILAEASLI
                     LFGLLPAPYNIGAMFLNGLSLGCMWGIIFSFIEGRRMTDILASLLGVSMVISSGTAKSA
                     GLYVMDTLNISEFWMPALIGGVALPLLALLGYALNRLPQPTAEDIAMKSKRETLNGKQR
                     WELFKNFMPFLTLLFIANVVLTILRDIKEDFLVKIIDVSQYSSWMFAQVDSVVTLIILI
                     IFGLMVFVRSNLKALSILLGLIIASMVVMAVVSFGYEQLQLNAIAWLFIQSLCLYLAFL
                     TFQTIFFDRFIACFKIRGNVGFFIAMNDFLGYTGTVIVLAVKEFFSPDINWTAFYNLMA
                     GYVGIICFVAFVCSFIYLHQRYRRENYGKTGVFRKKEEEKEVPDFVY"
     CDS             6623..6751
                     /locus_tag="ctg28_7"
                     /transl_table=11
                     /translation="MNLLCCNVYVIFMKRKRKEHRTSGHLFVIILTGSRCIPANIF"
     CDS             6832..7467
                     /NRPS_PKS="Domain: oMT (51-151). E-value: 1e-15. Score:
                     48.5. Matches aSDomain: nrpspksdomains_ctg28_8_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 101.8; E-value:
                     7.2e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_8"
                     /transl_table=11
                     /translation="MNKRGFVSKILQNFRKPEGFFGRMILWGMNTGHASLAQWGMSCLQ
                     WQPEWSVLDIGCGGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKYLGTRCFIEQ
                     GGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLICCEISDPANKAW
                     TGLVEGMEIHSCDELKAILSKSGFTDTTIFRTKKEELCLVSHRQTVRL"
     aSDomain        6985..7284
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_8_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.00E-15"
                     /label="ctg28_8_oMT.1"
                     /locus_tag="ctg28_8"
                     /protein_end="151"
                     /protein_start="51"
                     /score="48.5"
                     /tool="antismash"
                     /translation="VLDIGCGGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKYL
                     GTRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLI"
     CDS             7615..7800
                     /locus_tag="ctg28_9"
                     /transl_table=11
                     /translation="MLTSYSSLIKILLFDNQLLIFWMRSAVKFFSYIQDVRSCLFIKLP
                     LRLSIACLSTYFHILL"
     CDS             8181..8699
                     /locus_tag="ctg28_10"
                     /transl_table=11
                     /translation="METTDSDKHWYVVLTRTNSERKVRDYFQLQEVDTFLPVQNRVIER
                     EGKRIERERLLLPRMVFVHISRQEMAAVRSTLNVYDFLRDRSTGAPTCIPDAQMADFRY
                     MLDYSQDQVILTGESIPKGTRVVVAKGDLQGLRGELVRYNNKYHILVRIDMFGSAMVTI
                     PASYVRKEK"
     CDS             8882..9274
                     /locus_tag="ctg28_11"
                     /transl_table=11
                     /translation="MKNSLCNSVSSVVKKLLEYGEDGTPVYVNELTALNQELRNLCADL
                     LLQKGESPEEEAEILVTLFKGYDTMLFNFSSENEQVIQELLDRSMTILEKLPASVLKCQ
                     LLLECFEQTGDEELIREAKKNIERVI"
     CDS             9277..10161
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 276.9; E-value:
                     3e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_12"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.7e-12, bitscore:
                     37.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG
                     IREILIISTPDDLPGFQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCL
                     VLGDNIFYGDGLTEMVQFAVNKADLENKATVFGYWVSDPERYGVAEFDRSGNVLSIEEK
                     PQKPKSNYAIVGLYFYPNKVVEVAKNIKPSSRGELEITTVNQRFLSNRELKVQLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIALRKGWISPEKMKALAQPMLKNQY
                     GQYLLKVIDDLFV"
     CDS             10479..12008
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_13"
                     /sec_met_domain="Polysacc_synt (E-value: 1.7e-10, bitscore:
                     32.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFRSGYFQLFINIFTNVIAFGTSLCVSFVLTPYLISNLGKDVYS
                     FFPLANNFVNYMSIVIIALNSMAARFISIEIFKSNNVKAQEYISSIFISNVFLSVFLLF
                     PAVLIVCSLETLLNIPNSSIPDVKLLFALIFLSMIVNTLSSVFGVSVFAKNRLDLKAYK
                     EIIQGLLKGLLLLVLFLIYPPSIIYLGIVAVGLSFTNFGIDFIFTRKLFPTYVISFSYF
                     RYNLVKEVLISGMWNSINSLGSILLLGMSLFLANILIGPDASGELSIVQTLSGFMCGII
                     VLIYSVFLPRMTEKYANESYEHLAKEVRFSQKILSYFATTPTLLIILFGNSFFSLWMPG
                     ENSDYLQCLSVISMIPLLVHGNMWTIYGLNMTLNKQKNPSITLILFGVLNIVLVYFDHI
                     LLKGNLISLISISSFINVVYYLFYIPLYSTRQLGIKKIYFYSHMIKTFIFCLVVVIFGM
                     IFKNSLYINSWGLFFFYNIIFGCLFLLLHVWFTLNRGEKEKLIVWVKKKIQ"
ORIGIN
        1 tgcttacttt gcagaccaaa tcagattttt ggagaaattg attattaacg ctaaatcaaa
       61 ataacaaaat gtacttatta ttagttatct taatggttat tgcagccata ctgatgtgct
      121 tcattgtgtt gattcagaac tcaaaaggcg gtggtcttgc ttcagggttc tcatcatcta
      181 accagattat gggtgtacgc aaaactacag actttctgga aaaagcaact tggggcttag
      241 ctgcatttat ggttgtgatg agcattgcta ctgcgtatgt cgttccgact tcttcttcta
      301 aaacacaaga tgtcattatg gaacaggcac agcaggaaga gcagaccaat ccttataacc
      361 tgcccgtagg tactactgca ccgaagacag acgctgctgc tccggttgaa gcacctgcca
      421 cagaaactcc ggctactccg gcaaactaac aacagattct ttttaagaaa cgataagcga
      481 agctgcaatt tcaaaccgaa acttgcagct tcgcttattt tttgccgtaa aatgcatctt
      541 tttgttaggc atacaaggca gatttagtta cctttgttcg caataacact tttactaatt
      601 tctgagttta aatattacaa tgacagaaca attgaaaaac aaattgagtg actccaaaac
      661 acttcgttgg agtgtgctcg ctctggtcgc gtttactatg ctttgcggct atttcctcac
      721 cgatgtaatg tcccctttaa agcctatgct cgagaaagag cttctttggg atagtttgga
      781 ctacggattc tttaccagtg cttacggatg gttcaatgta ttcctgctca tgttgatttt
      841 cggtggtatt attctcgata agatgggagt tcgtttcacc ggtatgggag cttgtatact
      901 gatggtgttg ggttgtggac taaaatatta tgctatctct acaacttttc ctgagggagc
      961 tttgattatg ggtttcaaga ctcaggtctt tctggcggct ttaggatacg ctatctttgg
     1021 tgtcggcgta gagatcgccg gtatcactgt ctctaagatt atcgtgaaat ggtttaaagg
     1081 taaagagatg gctttggcta tgggacttga gatggcaacc gcacgtatcg gtaccacttt
     1141 ggctatggtg cttaccgttc ccattgccga ttatttcggc tatacggatg aaagcggcag
     1201 tttccatacc aatattccga tgcctatttt gttgtgcctg atcatgctgt gcatcggtac
     1261 tatcgccttt ttcatttata ccttttatga taagaaactt gacgcttctt tagatgctca
     1321 gggagaagaa ccggaagaac cgttccgtat gaaggacgtt atgctgattg tcaccaataa
     1381 aggcttctgg ctgattgctt tattgtgtgt actattctat tctgctgttt tcccctttat
     1441 taaatatgca accgacctga tggtgcagaa gtataatgta gaccctaagc tggccggaaa
     1501 tattccggga ttactaccga taggtaccat cttcctgact ccgttgtttg gtactcttta
     1561 tgaccgtatc ggtaaaggag cgacgttgat gattatcggt gccgtcatgc tgattggtgt
     1621 gcatactttg tttgcgcttc ccattctgaa cgtatggtgg tttgccactg tgattatgat
     1681 tgttctgggt attgcttttt cactggtgcc ttcggccatg tggccttctg ttccgaaaat
     1741 tattccggag aaacaactgg gtactgccta tgctttgatt ttctgggtgc agaactgggg
     1801 attgatgggg gtacctctgt tgatcggatg ggtgttgaat acctattgca aaggtcctgt
     1861 tgtggatgga gcgcagactt atgactatac tttgcctatg gctatctttg cttgtttcgg
     1921 tgttttggct ctgattgtag ctttaatgct gaaagcggaa gacaagaaga agggatacgg
     1981 actgcaggaa gcaaatatca aaaaataaca gtatatggca gacgtgaaag agaaaataaa
     2041 tcttctggat gtaattcctt tccgtagtga aaatattacg gccgaaaagg gaagcgatgg
     2101 taccgttacc attgctttcc cccggtttaa atacgagtgg atgcggcgat tcttgttgcc
     2161 taaaggaatg tctgcggata ttcatgtccg gctggaagat catggcactg ccgtatggga
     2221 gttgattgat ggaaagagaa ccgtacgccg gattattgaa gagctggcag aacacttcaa
     2281 ttatgaagaa aattacgaat cacgtattac ggcttatatc actcagttgc agaaagacgg
     2341 atttgtgaaa ttagtgattg agaactgatt gcattacgat atactattgg aatataataa
     2401 agagactccg gctgatttaa aaatgaagtg caccctaaaa gttaaacatg aacttttggg
     2461 gtgcacttca tttttaaatc agccggagtt tttgattatg ctttattctc cttcttctct
     2521 atctaccttg atcaagcctc ctgtatccgg gttgaaagta acctgaacag tcgatttctt
     2581 attgaaaagc gccggagcca gatattcgat agtaccgaat tgtgtgacag gaagttctcc
     2641 gttaaaccat tgctttttcc cctccgttag tgttacttgt gctttgccgg gcacattata
     2701 ggcaatgccg tccaccttct ttttgccatc gtcttccggt acgttgacgg ttttcagatt
     2761 cttcagcgtg atataaaccg gctctcctgc aagatcgtta ttggcaacta tgcccagctt
     2821 cttcgaaaag cggaaagcta cttcgttgtc catttcctta tccggagtga ggcggatgtt
     2881 gaatatcttt tcgtctttat tcaaggtacc cgagaacatt tcggtcatgg cagcctcttg
     2941 ctcttccagg ttggcgagca taatcttcag ttgctcccca tctttgggca tgttgtctgc
     3001 ctgtccgcgt accagggcat ttttactttc acgaatgtta taaatctctt tggcaaccaa
     3061 ctccgccatt ttagccgtag aacctgccat cagaatctct tcggtcagaa aatcacgtgg
     3121 atttatcttc tttttctgtg tcgtggcggg ttgcatcgga gccgattttt taggagatag
     3181 cggtacgttg attgatttta cgataccatc ttcggtcaat tctattagcg gagctactgt
     3241 tttatctttc agcttgacaa aataggtatg ttcgctatcg gggataccga cagattttgc
     3301 tttgacgctg accagttccc aatattcctg aggctcaccc gacacatcgg tcaaccggag
     3361 ataacggtcg gcatacttgc tgaattctcc cggagtatat gtcactttat tgactttgac
     3421 ttcaatattg attgctgttt taggaagtgc ataggttaca ccgtaatctt ttccccgggt
     3481 aactcccgct gtaacttcgg tctgggcata agccgaggta gagagtaaca gccctgtcag
     3541 tataattagc tttttcattt ccggtttatt ttaactggtt taaaaaacaa agttaatgaa
     3601 gttatttgga aaatcataag ttgttaactt ttattcgctt accagacgcc aagccaatgg
     3661 cagattactg ataatgtctc ctgccgtcat gctgataacg ccttgctttt tgcgtgcgaa
     3721 atcacctgcc agaccatgta cataagtacc gattttggca gcttcttcag ccggatatcc
     3781 ctgtgcgagc aaagccagca cgacacctgt caatacatct ccgcttccgg ctgttgccat
     3841 acccggatta cccgtagagt tgaaatagca cttgcccgag ggggtgataa ttgccgaata
     3901 ggctcctttt aatatgatat gtactttggc ggttcgggcc agttcacagg ccttcatcag
     3961 tcgttcgtat gagttctggc atttgcccac catgcgttcc agttctttgg gatggggagt
     4021 cagaatagag cctttgggca atgtggtcag tgcgtggcgg tggttggcca atatgtttag
     4081 tgcatcggca tccagtacca gaggtgtctg gcagccactg agttgttcaa gcagtgcagc
     4141 ttcggtctct tccgagcgtc cgatgcccgg accgattcct acagcctgat agtcatccgt
     4201 atctgtaggg caggcaaagt aggtatcgct ggcatccgat tcgataattg cctccggaac
     4261 cgaaatctgc aggatatcat tgttgcgtat aggtgcatgg actgtcagta agcctacacc
     4321 cgaacgcata caggcgcggg ctgccagtat cgacgcgcct gccatgccgt acgaaccggc
     4381 aatcagcaga gcatgcccaa agtttccttt gtgtgagaaa gtgttacggg gtttgatcag
     4441 agcgtgtatt tcttccgctt ccaataaggc ataattgctt tccgtctctt caatcgcttc
     4501 acgactgagg ttgatatcca acagtttcca ttcgcctatg aattcggaat tttcagcaaa
     4561 gaggaaagcc agtttcggca attgcaggct caatgtcaat tgggcacgga tgatattggc
     4621 ttttacatta aatgtgttct cttctcccat cagtcccgag gggatatcga tggcgactac
     4681 ggtggcaggc gatgcattga tatatttcac tactgccgca aaaccgccac ttagcggctt
     4741 attaagtccc gaaccaaaaa gtccgtccac taccagatga tccatcgtca gggcaggagg
     4801 tacaaactgt gtgcttactt cgctgaactt cacattatcc atcatctcta ccagctcctt
     4861 gttggtctgg cagtcggcag acagttcccc tttcgggtta aacagatagg cttcgacctt
     4921 gtattccttt tccgccaaca ttcgggccac ggcaagggca tctccgccat tgttgcccgg
     4981 tccggcaaat accgtgacgg gagttgtgat gtcccagcgt tcggtgatgg ctttggtcag
     5041 tgcctgtgcg gcccgctcca tcaggtcgat cgatgcaatc ggttcatgtt ctatggtgta
     5101 agcatccagt ttcttgatgc tgctacttgg aaaaatcttc atggtgaact ttcattttaa
     5161 gttttttgac ccacaaagat agcaattaat atacgaaatc gggaacttct ttttcttctt
     5221 ctttttttct gaatacccct gtctttccgt aattctccct gcggtagcgt tggtgcaggt
     5281 agatgaaaga gcatacaaaa gcaacgaaac agattattcc cacatatcct gccatcagat
     5341 tgtagaaagc tgtccagtta atgtccggtg aaaagaattc tttgacagcc aatactatga
     5401 ctgttcccgt atagcccaga aaatcattca tagcaatgaa gaaacccacg ttacctcgaa
     5461 ttttgaagca agcgataaaa cggtcgaaga agatagtctg gaaagtgaga aaagccagat
     5521 agagacacag gctctggatg aatagccagg cgatggcgtt cagctgcaat tgttcgtaac
     5581 caaacgaaac gactgccatc actaccatgc tggcaatgat caatcccagt aatatcgaca
     5641 gtgctttcaa gttgcttctg acgaacacca ttaatccgaa aattatcaga ataatgaggg
     5701 ttactacgct gtctacctgt gcaaacatcc acgaagagta ttgagagaca tcgataattt
     5761 ttaccaggaa gtcctccttt atatctctca agatagtcag taccacattg gctataaaga
     5821 gcagagtgag gaaaggcatg aaattcttaa atagctccca tcgttgcttg ccgttcagtg
     5881 tttcccgttt cgatttcatg gcaatgtctt cggctgttgg ctgtggaagc cggttgagtg
     5941 catatcccaa caaggcaagt agaggaaggg caactccgcc tatcagggca ggcatccaga
     6001 attcgctgat gttcaaagtg tccatgacat acaaaccggc cgacttggcg gtacccgagc
     6061 tgatgaccat actgactccg agtaagctgg caagaatgtc cgtcattcgt cttccctcga
     6121 taaagctaaa aatgattccc cacatacatc ccagtgaaag tccgttcaga aacatggctc
     6181 ctatattata aggtgcgggc aacagtccga acaatattaa cgaagcttca gccagaatta
     6241 tggagatcag aataaacttc atccggtttt ctcgttttaa ttcggagatt aatttaattc
     6301 cgatgaattt agaaagtaca tatcctaata tttgtgcgat ggtaactacc actttgtagt
     6361 ccattccaaa cgcttcaagt ccgtcaaatc cggctgctgt gtaaggcttt ctcagtgcat
     6421 ataccaatga ataggagagc agcgctgctc cgcctgccca aagaatgaaa aggaaatcag
     6481 aaatttttct ctgcgaataa gtttttactt gctgtacatt gttcataaca tctgcttgtt
     6541 gttttccggt gcaaaaatag gagggtagtg ttacagacct gttactgaat atatgaatgt
     6601 ttattattaa tagatattga taatgaatct gttatgttgt aatgtttatg taatatttat
     6661 gaaacggaaa cgaaaagagc atcgcacctc cgggcatctg ttcgtcataa ttttaacggg
     6721 aagcagatgc atacctgcaa atatatttta ggaaataaat tccctatttc tgggtattgc
     6781 ctgtttgggc agaaactgta cttttgcctg aaatattaaa tcagcagaca aatgaataag
     6841 agaggctttg taagcaagat cttacagaat ttccggaagc ctgaaggttt tttcggaaga
     6901 atgatacttt gggggatgaa tacaggacat gcatcattgg cgcaatgggg aatgtcatgt
     6961 ttgcaatggc aaccggaatg gagtgtactc gacatcggtt gcggtggtgg tgccaatttg
     7021 ctacagatat tgcaacgttg cccgcaaggg aaagcgtatg gcatagatat ttcaccggag
     7081 agtgtcacct ttgcgcgtaa aaaaaataaa aagtatctcg gtacacgctg ctttatcgag
     7141 cagggaggag tccaccgact tccctatcct gattatgcgt tcgatgcggt cactgctttc
     7201 gagactgtct acttctgggg taacctgcag catgctttta cggaagtggc gcgtgtgtta
     7261 aagcccggtg gatcgtttct tatctgttgt gagataagcg atcctgccaa taaggcttgg
     7321 acgggacttg ttgaagggat ggagattcat tcctgtgatg aactgaaggc gattctttcc
     7381 aaaagtggtt ttactgatac gaccatattc cggacgaaga aagaagaact gtgcctggta
     7441 agccatcggc aaactgtgcg gttgtaacca atgccgggac gctcttacca acgaatacgt
     7501 taacaatgtt aatgcccgta aaagtgcttt ccctccttat caatagctta ttaacttcgt
     7561 atctctaaag aattaatatc ttgcaattac gaagttaata ttaacgtact gttaatgtta
     7621 acttcctaca gttctcttat taagatatta ttgtttgata atcaattgct tatattctgg
     7681 atgcgttctg ccgtaaaatt cttctcttac attcaagatg tgcgtagttg tctgtttatc
     7741 aagttaccgt taagactctc catagcctgc ctctccactt atttccacat tcttttatga
     7801 gccacattag tattatgtat attgctactt tccttatttg caaagagata aattatatct
     7861 ttgatattca gttatataac ttcctatgat gaaaataacc tgtgaaaagt tttggagact
     7921 caaaagaagg ttttaccttt gtacccgtaa atatataggc ggacaaatat acttttcttt
     7981 atgtccgata tatgtttaaa ataaaataat tcaacgtatc ggatagtatt caaatccggt
     8041 gcgaatactt tttctgtacc cgattatcat agaacttaat ttgtaaatta ctgaaaataa
     8101 ggcatgtttt ttgaatattc ctgtttttaa caaattttca tccttagtca ttactgaaac
     8161 tttttcttac gaacgtagtc ttggagacaa cagatagcga taaacattgg tatgtcgtac
     8221 tgacacgaac taactcagaa cgtaaagttc gggattattt tcaattgcag gaggtagata
     8281 cctttcttcc tgtacaaaac cgtgtcatag agcgtgaagg aaaacgcatt gagcgtgagc
     8341 gccttttgtt gccccgtatg gttttcgttc atatctcccg tcaagaaatg gccgccgtcc
     8401 gaagtacact gaatgtatac gatttccttc gtgatcgttc caccggggct cctacctgta
     8461 ttcctgatgc gcaaatggct gattttcgct atatgctcga ttactcccag gatcaggtga
     8521 tcctgacagg agagtccatt cccaaaggta ctcgtgtagt agttgccaag ggcgatttac
     8581 aaggcttgcg gggagaattg gtccgctata ataataaata tcatatttta gtacgtatcg
     8641 atatgttcgg tagcgctatg gttacaattc cggctagcta cgtccggaaa gagaaataaa
     8701 aagtatatat gtgaagaaaa taccattata tgtaatggcg ataacaatat atgtaacggg
     8761 tgataacaat atatgtaatg ccccgttacg tcgttagata caattctatt ggatattatt
     8821 actcttctat acaaataaaa accgaaaaga atcgacgaat cataattcat tcctttttaa
     8881 aatgaaaaat tctctgtgta attctgtgtc ctccgtagtg aagaaactct tggagtatgg
     8941 cgaggacggt actcctgtct atgtgaatga acttactgcg ttaaatcaag aactccgtaa
     9001 cttgtgtgcc gatcttcttc ttcagaaagg agaatctccc gaagaagagg ctgaaatact
     9061 tgttactttg ttcaaaggtt acgataccat gctgtttaat ttctcctctg agaatgaaca
     9121 ggttattcaa gaattattgg atcgttcaat gactatttta gaaaaactac cagcttctgt
     9181 attgaaatgt cagttgctgc tggagtgctt tgagcagacg ggagatgagg aactgataag
     9241 agaagctaag aaaaacatag agagagttat ctgacaatga aaggtattgt tttagcaggt
     9301 gggtcgggga cacggttata tcctataact aaaggagtga gtaagcagtt gcttcctatc
     9361 tttgataaac ctatgattta ttatcctatt tctgtactaa tgttggcagg tatacgggaa
     9421 attctcatta tttctactcc agatgacttg ccgggatttc aacgtttatt gggtgacgga
     9481 tctgattttg gggtgaggtt tgagtatgca gagcaacctt cacctgatgg tttggcacaa
     9541 gcttttatca taggagaaaa atttataggg gatgattctg tctgtttggt tttaggtgat
     9601 aatatttttt atggagatgg tttgaccgaa atggttcagt ttgctgtgaa taaggctgac
     9661 ttagaaaata aagcaaccgt ttttggttat tgggtaagtg atcccgaacg ttatggtgta
     9721 gcggaatttg ataggagcgg gaatgttctc agcatagagg agaagcctca gaaacctaaa
     9781 tctaattatg ccattgtagg actatatttc tatcctaata aggtggttga agttgcgaag
     9841 aatattaaac cctcttctcg tggagagcta gaaataacaa ctgtcaatca gaggtttcta
     9901 tcaaatagag agctaaaagt gcaattgtta ggtcgaggat ttgcttggct tgatacaggt
     9961 acacatgatt ctttatccga agcaagtact tttattgaag ttattgagaa acggcaaggt
    10021 ttaaaagttg catgtttgga gggaattgct ctaaggaaag gttggatttc gccagaaaag
    10081 atgaaagcat tggcacagcc aatgcttaag aatcaatatg ggcagtatct attgaaagtt
    10141 attgatgatt tatttgtata ataaaattgt ttgtttttta tatataacaa acagagttat
    10201 taagcccttt attatcgtta atttttggta tttatgggta atgtttgtaa atacttttgt
    10261 tgttgtaaag tataatggct catagaaaat ttgtacatcg taataataga taagattaca
    10321 tatttgatgg tatcctcttc attatttcaa tcagttgttt ttatagaaat tacaccatgc
    10381 taccaagtgt gtttttcgaa aatataataa gaaatgaaat aataggtata ttgaaaagtt
    10441 gagaagagaa ttagtaatca aatacgagat gaatagaaat gaaatttaga tctggatatt
    10501 ttcaattatt tatcaatata tttactaatg taattgcgtt tggaacttct ttatgcgttt
    10561 catttgtctt aacaccttat ctgattagca atttaggaaa ggatgtatat tcgtttttcc
    10621 cattagctaa taattttgta aattatatgt ctattgttat tattgctttg aattccatgg
    10681 ctgcccgatt tatttccatt gaaatattca aaagtaataa tgtaaaggct caggaatata
    10741 tttcttctat ttttatttct aatgtgtttc tttccgtatt tttactgttt ccagctgttt
    10801 tgattgtttg ctctttggaa actttattga atatcccaaa cagctctatt ccagatgtaa
    10861 agttactttt tgccttaata tttttatcga tgatagtaaa tacactaagt tctgtttttg
    10921 gtgtttcggt atttgctaaa aatagacttg atctcaaagc atataaagaa attattcaag
    10981 gtttactcaa aggccttttg cttttagttc tttttttaat ttatcctcct tcaattatct
    11041 atttgggtat agttgctgta ggattgagtt ttactaattt tgggatagat ttcatattta
    11101 ctagaaagtt gtttcctact tatgtgattt ctttctccta tttccgatat aatttagtaa
    11161 aggaagtctt gatttccggt atgtggaatt ctataaattc tctaggctct attctattat
    11221 taggaatgtc tttattttta gctaatatat taattggtcc ggacgcctct ggagaactgt
    11281 caattgttca aactttatca ggatttatgt gtggtataat tgttcttatt tattctgttt
    11341 ttttacctag aatgacggaa aagtatgcaa atgaaagcta tgaacatttg gcaaaagaag
    11401 tgcgattctc tcaaaaaata ttgagctatt ttgcaacaac accgactctt ctgattattc
    11461 tgtttggaaa tagttttttt tctttgtgga tgcctgggga aaattcggat tatttgcaat
    11521 gtttatctgt catttctatg attcctttat tagtgcacgg aaatatgtgg actatttatg
    11581 ggctgaatat gacattgaat aaacaaaaga atccctccat taccttgatc ttatttggcg
    11641 tactgaatat tgttctagtc tattttgatc atattctatt aaaaggaaat ttaatttcct
    11701 taatatcaat tagctcgttc ataaatgttg tttactactt attttatatt ccattgtatt
    11761 caacaagaca attgggaata aagaaaatct atttttattc ccacatgatt aaaacattta
    11821 ttttttgttt ggtggtggtc atatttggaa tgatatttaa aaacagccta tatattaatt
    11881 cttggggact tttctttttt tataatatta tttttggttg tttgtttctt ttgttgcatg
    11941 tatggtttac tttaaatcgt ggggagaagg aaaagttaat tgtttgggtg aaaaagaaaa
    12001 tacaatgaag atactctatt tttttaaaga agatgatact tatatgactc aatggcaaag
    12061 agttcatata tttgatgaat tgaagcatca taatgtgaat attacagttt taaatccgtc
    12121 aaaatatgaa actgtttgtc aggcaaatga ggacctgatt aatctgctaa gatataataa
    12181 agatcattat gacttattta tgaattgttg tggctctgac ttattattac ctgaaacgat
    12241 ggaagcctta aaggatctgt ctatacctaa acttctaatt tgctttgata atcttcatgc
    12301 cccttatatt cataaagata ttgccccttt tttcgatttg gtttggttaa cctcttttga
    12361 aactaaga
//
