LOCUS       c00128_gnlPro..        16829 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALHIGKOD_128.
ACCESSION   c00128_gnlPro..
VERSION     c00128_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:14:05
            Original ID  :: gnl|Prokka|ALHIGKOD_128
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 87691
            Orig. end    :: 104520
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16829
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[97691:100662]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16829
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16829
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(508..1017)
                     /locus_tag="ctg128_66"
                     /transl_table=11
                     /translation="MKKVCMLLLWLFICNIGLVLAQGRRFEFELGANYPIGLQKNGYKE
                     NHVGFYLNGIYRFPTNPLSVNLKLGYESYTIVLNNTFNGRSLSLMPAANYYFLRNESVD
                     SYVGLGTGVSIDNIDVGVFNEGYKLHFAVAPQVGIRFINHINVYLQYYVTHKDFSRLVL
                     GVGYVF"
     CDS             complement(1083..2630)
                     /locus_tag="ctg128_67"
                     /transl_table=11
                     /translation="MRILRYTLFLFAIGLISCEQEFDKKEQQSDCCSFQNLPKYPEQVV
                     NINVHNYIPDMGDKVLSSPSHIHTRASEIISETLWDNGFGKTIHAQADESIVLDNLNRY
                     IYPGSILDGASVANQDYKTISVHYKPINVSVSFPAQKVTGVLEKPSLSSCRQLVMDLMH
                     QKGIGQQSASVHFDIHRFTSYDELKMTFGSNANTSFLFWGSSSSQQEHKERISKSSGLY
                     IRFIQKYFTIDMDIPEKSFIEGSINAQYSPVYVSSIAYGRVGILTLETDEIYENAESIV
                     KKAVNGFLYNKKEFLTVEEKGFFDEARMKVYVGGGNGDSGVKTLTGFDDFIKFISEGGH
                     FSAETPGKPIFCSFAYLSDHSPYKVKFKIDIDSDPVYARIEYRNLKNDSYVGRSLQREK
                     IIGDVHLAFYADRTAKIPTVAPRYISFNIVEHSRHYLKARIPRTEKDDTAVEEFVKSNN
                     SRGTELQLKHDLLLTEFVWTHNNPRRTRYEQNTFRYSLSEGGFYKILPAINEPKKWR"
     CDS             complement(2646..3752)
                     /locus_tag="ctg128_68"
                     /transl_table=11
                     /translation="MKQYVYLLILPIMFLISCSDDTVEEMGGSNHVLLERYPQEVINIS
                     MDNPESFASFNKTSVTRSSELLKDSVWSSGNGHTLIYETNEHIPTQGLMRYIYLGSILQ
                     GGSIEKQRFVPIVKPMDPITISYSFPARWVTDIIAKPSLSAQRQSLQNIMNKEGMTGKQ
                     LGSFTYNMRQFSYFEELKLAFGANVNIGGLLNIDVSLDKGKIRKKTGLFAKIVQRNYTV
                     DMDLPADGNILLNHDDMGSVGKYDPIYISSITYGRMALISIESSESYDKVRIALQAALQ
                     AKVVNGKLSFNLEQEKILKEAEVNVMVYNGEGEGTVKTAKGWNEFQDFIIQGGRFSKDL
                     PGDAIFYTASYLSDNSPFYSKFKIHLEN"
     CDS             complement(3785..4624)
                     /locus_tag="ctg128_69"
                     /transl_table=11
                     /translation="MKKIFILLFVSLALFSCEKEENNKIFKYQLLPSENVSKPFSCLGE
                     KRTITFTIIQKTLIDDILDSEVPIIPKDISIEFDKTLFSDIETKIKGDQVVLNITSNIN
                     KEDKILNVDLQISYSTINGIKVEKIPLIIDKGKLTFVYKIHSEQNPFVLPAEGGKFELP
                     FICKKQTYLNDQFIEETYSSLNGLRFKTISTGNVWFLTVRKDGEKIGFYKFTFVGEGPY
                     NQKTDPECYFNIYTHDANLITDNPTEIFRQDFIQPQTPGEDYYKPSRSSYKHGTFDF"
     CDS             complement(4721..5128)
                     /locus_tag="ctg128_70"
                     /transl_table=11
                     /translation="MFSCSNEERNRLPSITPSHIDLSPEHPEAYFQIACGDYNMSGFII
                     VGQEEYRITKGIMSKEVTVVELSGGSKATFHCRNRILVKIDFGFMTISKIQRGKYKVQL
                     NKNIDIRQPIAISFGFSVPGGISTVVVTLKQ"
     CDS             complement(5286..5408)
                     /locus_tag="ctg128_71"
                     /transl_table=11
                     /translation="MKKIVFVLFGCLILFQSCSNVFYNHANKTEKVTVKVKPFK"
     CDS             complement(5421..6212)
                     /locus_tag="ctg128_72"
                     /transl_table=11
                     /translation="MYRKVTTLINFAAFVLFWIIMLLFYFPLDAYGQESKWGNMNPVRE
                     GYLRSNKDFAVDSVKYPIGRYRNSVISTNSGVTFQFKKGGPFFYTDQNPLHKGEYNVSG
                     VIGPLWNGHVYGMGRQMNLIGIGVFNYAAIGYNKSLSDNLFADVALHAMKLSTPRHVDE
                     TFGISGKLSYSFNSRMSLHVFGGFLFTPVTSFSRNDYGGSVAFDITDSFGTELGIRGYR
                     EYPFERGGVTPILMPYYKFKKHKVEMDFGGLLQEIIYGLFK"
     CDS             complement(6933..7346)
                     /locus_tag="ctg128_73"
                     /transl_table=11
                     /translation="MFLLRTFMLQSLQDQIASLLFGAILVSIYIYMLIVIPSFICLEKD
                     QLVIKRVFGKKCIPYSCIKNAFVYDGVQNDVRYFGSNGFLGYIGVMGSTHYGKYYSYVK
                     NPNQQIFILTEKKNYLLSCENRDMFIKDLLIHL"
     CDS             complement(7430..8221)
                     /locus_tag="ctg128_74"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENFVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKNCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             complement(8211..9128)
                     /locus_tag="ctg128_75"
                     /transl_table=11
                     /translation="METYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAHKKGLI
                     TRVVTNGYWAVSYEKALGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRAAAKVD
                     LPCLVNIETNPSSQFSEEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRDTNYNE
                     LIKHRYVQRPIISHGCNSLFESIPIDPEGNVYACCGLACRKAKLLKIGNMNTAGINKIY
                     TRQFDDFLKVWAYVDGPKFILNKIAMETGKNIEVNADMHNCEACLLLLNDPSKIEYIKN
                     NISRYISEVVLKYNIKQKKANYEK"
     CDS             9667..9852
                     /locus_tag="ctg128_76"
                     /transl_table=11
                     /translation="MFIAERQGFEPRVPRGTTVFKTAAIDHSATSPKLPYQKCFSLKAV
                     QRYEDILNLQEFSLKI"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_77"
                     /sec_met_domain="Gly_radical (E-value: 5.2e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12243..12971
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_78"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(12964..13413)
                     /locus_tag="ctg128_79"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(13400..13567)
                     /locus_tag="ctg128_80"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(13627..14130)
                     /locus_tag="ctg128_81"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             14324..14554
                     /locus_tag="ctg128_82"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             14641..16755
                     /locus_tag="ctg128_83"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYACTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
ORIGIN
        1 cggcagaaaa tcgcagaata cgacaatcgg ctggaactga tagacaccta ctttcctatt
       61 gtaaaggaac tgatacccat agcagaacaa tgccgggaag tgggcttcac cgaagaactg
      121 acaagacgaa ttgtcagcct gcaacccgtg gagttcaagg gaaggctcta ttcaaaggag
      181 tacaaggaga agttcaggac ggagcactca acggcaacag tggagaggaa cccccaggag
      241 aaaggaaaat tcaggctgtg cattgacgga atacccatac tcgattggtt caggaagaaa
      301 tttcaggaaa ttaaagaaaa gttagggcta aacacacctg ttgaaaacaa gcaacgaaaa
      361 ggattgaaaa tataattact taataacgag aggctataaa ttattattgc cagtaaaaga
      421 atatactctt tactggcacc tgttaaacgc aaattgacac cctaaatcta acaaatataa
      481 aaaaatctat tcttcacttg gacaatatca gaaaacataa ccaactccca ataccaacct
      541 ggaaaaatct ttatgtgtca cataatactg taaatataca tttatatggt ttataaatct
      601 aataccaact tgtggagcca ccgcaaagtg caacttataa ccttcattga aaactcccac
      661 atctatatta tcaattgaaa caccagttcc caaaccaaca taggaatcaa cagattcatt
      721 ccgtaagaaa taataattag ctgccggcat aagagataaa gatcttccat taaaagtatt
      781 attcagtaca attgtgtaac tttcataacc taattttaga tttacactta acggattggt
      841 gggaaaccta tatattccat ttaaataaaa cccaacatga ttttctttat atccattctt
      901 ttgtagccca attggataat tggctcctaa ttcaaattcg aatctccttc cttgtgctaa
      961 taccagccca atattgcata taaataacca aagaagtaac atacatactt ttttcataac
     1021 caatttatct tttaatacca tatctcttat ttatttgtcc gacaaggagt gctaacttca
     1081 aattatcgcc acttctttgg ctcatttata gcagggagaa ttttgtaaaa accaccttca
     1141 ctaagactat atctgaaagt gttttgttca tatcgagttc ttcttgggtt attatgcgtc
     1201 caaacaaatt ctgtgagcaa caaatcatgt tttaattgta attcagtccc acggctatta
     1261 ttactcttaa caaattcttc tactgctgta tcatcctttt ctgttcttgg tattcgagcc
     1321 ttcaaataat gtctgctatg ttctacaata ttaaaagaaa tgtatcttgg agcaactgtc
     1381 ggaatcttag ccgttctatc agcataaaag gcaagatgta catcgccaat tatcttttct
     1441 ctttgtaaag atctacctac ataggagtca ttttttagat tccgatattc aattcttgca
     1501 tatacaggat cgctatcaat atcaatttta aatttaactt tataaggtga atgatccgac
     1561 aaatacgcaa agctgcaaaa tataggttta ccaggtgtct ctgcagaaaa atgccctcct
     1621 tcacttataa atttgataaa atcgtcaaat ccggtaaggg tctttacacc actgtcacca
     1681 tttcctcccc ctacatatac tttcattctg gcctcatcaa aaaagccctt ttcttcaact
     1741 gtcagaaatt cttttttgtt atataaaaag ccattaacgg ccttctttac aatggactcc
     1801 gcattctcgt atatttcatc ggtttcaaga gttaatatgc cgacccttcc ataagctatg
     1861 gagctcacat agacaggaga gtattgggca ttgatactac cttcaataaa actcttctca
     1921 ggaatatcca tatcaatcgt aaaatatttc tgaataaacc ttatatataa gccactactt
     1981 ttactaattc gttccttatg ttcttgttgg gaagatgacg acccccaaaa taaaaagctc
     2041 gtattggcat ttgatccaaa agtcattttc agctcatcat aagatgtaaa acggtgtata
     2101 tcaaagtgta cggaagctga ttgttgtcct atacctttct gatgcatcaa atccattacc
     2161 aactgcctac atgaagacaa agagggcttt tcaagtacac ctgtaacttt ttgggcagga
     2221 aaggacacag agacatttat aggcttatag tggacactga ttgttttata atcctgattg
     2281 gcaacgcttg ccccatccaa gatagagcca ggataaatat atcgattcaa attatccaaa
     2341 actatcgact catctgcctg tgcatgaatt gttttaccaa acccattatc ccataatgtc
     2401 tcagaaatga tttctgaagc tcttgtatgg atatgcgaag gagaagataa aaccttatct
     2461 cccatatcag gaatatagtt atgcacattt atattcacca cttgttcggg atacttaggt
     2521 agattttgaa aagaacagca atcagattgc tgttcttttt tgtcaaattc ttgttcacat
     2581 gaaattaatc ctatagcaaa taaaaacaga gtatatctta agattctcat ggttctaagt
     2641 tattgtcaat tttctaaatg gattttaaat ttggagtaga agggagagtt atcagataaa
     2701 taactcgcag tataaaaaat tgcatctccc ggcaggtctt tagaaaatcg acctccttga
     2761 attataaaat cttgaaactc attccacccc ttcgcagttt taacagtgcc ttctccttct
     2821 ccattataca ccatgacgtt cacctctgct tctttaagaa tcttttcttg ttcaagatta
     2881 aaagataatt tcccatttac aactttagct tgtaaggcag cttgtaaggc aattcttact
     2941 ttatcataac tttcagaaga ttctatcgaa attaaggcca ttcttccata agtaatggaa
     3001 ctgatataaa taggatcata cttaccgaca gatcccatat catcatgatt taaaagaata
     3061 tttccatcag caggaaggtc catgtcaaca gtgtaattac gttgtactat tttcgcaaac
     3121 aatccggttt tctttcttat ttttccctta tcaagactga catcaatatt aaggagcccg
     3181 cctatgttga catttgctcc aaaagcaagt tttaactctt caaaatagga aaattgcctc
     3241 atattataag taaaagaccc caactgttta cctgtcatgc cttctttatt cattatattc
     3301 tgcaaagatt gcctttgtgc tgaaaggctc ggttttgcga taatatcagt aacccaacga
     3361 gctggaaaag aatatgatat tgtaattgga tccataggtt ttacaatagg aacaaagcgc
     3421 tgcttttcaa tagatccacc ttgaagaatt gaacctaaat aaatatacct cattaaccct
     3481 tgagttggta tatgttcatt tgtttcataa attaatgtat gtccatttcc actactccat
     3541 acactatctt tcaataattc agaagaacga gtaacggagg ttttattaaa tgaagcaaag
     3601 ctttctggat tatccattga aatatttatc acttcttgag ggtatctctc aagaagaaca
     3661 tgattagagc cccccatttc ttcaactgta tcatcggaac atgaaattaa aaacataatt
     3721 ggcaaaatca acaaatatac atactgtttc ataattaata taattaaggt taatactgaa
     3781 tatgttaaaa atcaaaagta ccatgtttat aagaggatcg agaaggttta taataatcct
     3841 cacccggggt ctggggttgt atgaaatcct gtctgaatat ttccgtagga ttatctgtaa
     3901 ttaaatttgc atcatgggta tatatgttaa aatagcactc tggatctgtt ttttggttat
     3961 atggtccttc tcccacaaaa gtgaatttgt aaaaacctat tttttctccg tcttttctga
     4021 ccgtaagaaa ccagacatta ccagtactta tcgttttaaa tctcaatcca tttaatgatg
     4081 aataagtttc ctctataaac tgatcattca aatatgtttg ttttttacaa ataaagggca
     4141 attcaaattt cccaccttca gctggtagaa caaaaggatt ctgttccgaa tggattttat
     4201 acacaaatgt caacttccct ttatctataa ttaggggaat tttttctact tttataccat
     4261 taatagtaga gtaagaaatc tgtagatcaa cattcaaaat tttatcttcc ttattaatat
     4321 ttgaggttat atttaataca acttgatcac cctttatttt tgtctctata tcagaaaaaa
     4381 gagttttatc aaattctatc gaaatatcct tgggaataat cggaacctct gaatctaaaa
     4441 tatcatctat caatgttttt tgaataattg taaaagtaat agtacgtttc tcccccaaac
     4501 aactaaatgg tttagatacg ttctcacttg gcagcaactg atatttaaaa attttattat
     4561 tttcttcttt ttcacaggaa aataatgcta aggaaacgaa cagaagaatg aatatttttt
     4621 tcatattaac acagtttagt tttttgcaaa ttaaagaatt tttcctgtac aataaaatac
     4681 caattaattg gtattttatc acaaataacc attcatgtat ttattgtttc aaggttacaa
     4741 cgacagtaga tattccacca ggaacactga atccaaagga aatggcaatt ggttgtcgta
     4801 tatcaatatt cttattcaat tgaactttat atttgcctct ttgtattttg cttatggtca
     4861 taaaaccaaa gtctatcttt acaagtatgc gattcctaca atggaaagtg gccttacttc
     4921 cgccagaaag ctcgacaaca gttacttcct ttgacattat tccttttgta atcctatatt
     4981 cttcctgtcc cacaattata aatccagaca tattgtaatc accgcatgct atctgaaaat
     5041 aggcttcagg gtgttccggt gacaggtcta tgtgactcgg ggtaatactt ggcaatctat
     5101 ttctctcttc attagagcaa gaaaacatta aaattattgc tatacataac aataggtatt
     5161 ttgttgtatt cattatggca aatatttggt tgtatgaata tttaaagcct cagtcttgta
     5221 cggggcatag cattccttcc aacgggtatg ttgaaaacga tccgcatttt tactgaacaa
     5281 ttattttatt taaaaggctt taccttaaca gtaacctttt ctgttttatt agcatggtta
     5341 taaaacacat tactacaact ctgaaagaga atcaaacatc cgaacaatac aaatactatt
     5401 ttcttcataa attatacttt ttatttaaac aatccatata ttatttcttg taacaatcca
     5461 ccaaaatcca tttccacttt atgcttttta aatttatagt aaggcattaa gataggagta
     5521 actcccccac gttcaaaagg atattcacga taacccctta tacctaattc cgttccaaaa
     5581 gaatccgtta tatcgaaagc gacactgcct ccgtagtcat tacggctgaa tgaagtaaca
     5641 ggagtaaata aaaaaccgcc aaatacatgc aaactcattc gggaattaaa ggagtaagaa
     5701 agtttacccg atataccaaa tgtttcatcc acatggcgag gggtacttaa cttcattgca
     5761 tgcaatgcaa catcagcaaa taaattatct gacaatgatt tgttatatcc aatagcagca
     5821 tagttaaaaa caccaatacc aattaaattc atttggcgcc ccatgccgta aacgtgacca
     5881 ttccacaatg gtcctattac ccccgacaca ttatattccc ctttatgtaa aggattttgg
     5941 tctgtataaa agaacgggcc acccttcttg aactgaaaag taacaccgga atttgtagaa
     6001 ataacagaat ttcgatatct cccaatagga tattttaccg aatcaactgc aaaatcttta
     6061 ttagaacgca aatacccttc tctcacagga ttcatattac cccacttcga ctcttgacca
     6121 tacgcatcaa gaggaaagta aaacagcagc ataatgatcc aaaataaaac aaatgctgca
     6181 aaattaatta atgtagtcac ctttctatac atattaattg ttatcattat acccaaagca
     6241 tgaaaataaa agtataacat acaagagctg taaacaaatc cactatcaac acaataaaat
     6301 aaatcgtttt tgcatcttat ctttgcgata tgtatttatg caaaaatatg taattttctt
     6361 tatcagtaaa atacccatta attagtattt cattgacaaa atgaaatgta ctttaaaagc
     6421 caaaagttat attcaattca taacctaaat gcctatccaa tataaataat gcttttagca
     6481 ccaagataca aacagaataa cacaaaatca acctttaaag gaatgtatta ctattataaa
     6541 agacagaatt attcgggaga ttccccactc taaaaatgta aaaaaaataa aatgatataa
     6601 ataaatatta gtataacaat gtcatcaacg atacaatatc ccctttgtaa attatacaat
     6661 aaataatagc taagcaacca aagacagtgc aaagcccaac aagtaataaa agaacaaagt
     6721 attaaataaa gcaaaaacac ccaattttac tttttagggt ataaaattgg gtattactct
     6781 tgtaattcac agattttcaa catttattgc agagatacag ggtttaatta ttaatgctct
     6841 aaaaaactaa cgggaagaat aaaaaacata ttcttcccgt caagtaatac tataactata
     6901 ttttccaaca ggttatatta atatccagca tattataagt gaatcaacaa atcttttata
     6961 aacatatctc tgttctcaca gcttaagagg taattctttt tttctgttaa tataaaaatt
     7021 tgttgattgg gattctttac ataggaataa tattttccat aatgggtact gcccattaca
     7081 cctatatacc ccaaaaagcc attacttccg aaataacgga catcattttg aacaccgtca
     7141 taaacaaaag cgttcttaat acaagaatac ggaatacatt tcttaccaaa cactcttttt
     7201 ataacgagtt gatccttttc caaacatata aatgaaggaa tcactatcag catgtatatg
     7261 tatatagata caagaatggc accaaataac aggcttgcga tttgatcctg caaagattgt
     7321 agcataaaag ttcttaatag aaacataagg ccagtagtta ataagacaat ctttaatacc
     7381 agagaccaac gctccattac cggctgaaat tttgatttat atacgctcat tatattgcta
     7441 atgtcttctg tattatttca ataagttctt tatccgtata tcgttccata acctcaggac
     7501 gtttttcttt tactaactta accaaatctt gaacatagtg atttttgtac tcatctgcta
     7561 actcatatac acttccgtcc tgtgtttcaa cgtcccaaac ctgcaatgcc atttcactgt
     7621 taattgttct ggaagcacat actacgggac caccaagtgc tgcataatca attcctgccc
     7681 caacatatgc aacacctaac aaaatccatt caccgatcca aaagaatccc atttgcacat
     7741 ctacacagtt tttacttctt gttattgcag tatggttcaa taatttaata ttggaagaat
     7801 tggcattttt aaaaatatca tacttttcac ataattctac aaatcttcta atatctctct
     7861 ttattacagc ctctcgaaat tccggcttac aaattgctaa taaaaaacgt acagtaccgt
     7921 catcagtatc tatagagctt tttattccca aagaccgggc atattccaaa ggggcattca
     7981 aaaaggcttc cgctgcattt gtatcattta aaatattatg tgataataaa ctcatatcgt
     8041 gaatatacac ctgttcctcc tgtgataact ttttcataga aatagcagta gtttcatcat
     8101 ctacaaaatt ttcttctgac gcaatagcta aattaggaaa atcatttgaa ttatcacatg
     8161 aagaaaatga agtagcagct attgctgccc caacacctaa agttagaatt ttacttttca
     8221 tagttcgctt tcttttgttt aatattatac tttaatacaa cctcagatat atatctggat
     8281 atattgtttt taatatactc tattttagag ggatcattca acagcaatag acaggcttca
     8341 caattatgca tatcagcatt aacctcaata tttttcccgg tttccattgc tattttattt
     8401 aatataaatt tcggcccatc aacataagcc catactttta aaaaatcatc aaattgtctt
     8461 gtatatattt tatttatacc ggcagtattc atatttccaa tttttaaaag cttagctttt
     8521 ctacaagcca gtccacaaca agcatacaca ttcccttccg gatcaatagg aatactctca
     8581 aatagactgt tgcacccatg ggatattata ggtctctgca catatctatg ttttattaat
     8641 tcattataat ttgtatcacg tttaatttta tcctccatat caaatggaat ccatatacca
     8701 gaagaaaaga taactttatt atcccgtata tactctttta actcttcatg atttttgaaa
     8761 tcttcctcag aaaactgtga acttggattc gtttctatat tcaccaaaca aggcaaatcc
     8821 actttagctg ctgctcttat agcatttacg atattatcaa agggcaccca tttttgatga
     8881 tcatcccccg tgcttaaatt taattcattt aaccccaact cctttagtaa caccaaaatt
     8941 ccaagagcct tttcataact aacagcccaa tacccattag taacaaccct tgttataagc
     9001 ccctttttat gtgcataata aatagcttga tataaatcat cttttaagga aaaacattct
     9061 ccaccactaa agacaaccag cctaatcgta gggaaagctt ttacacattc cgatatatag
     9121 gtttccattt gtttaaatga cattctcccc ctacgttctt ggttacactc aaaacaacaa
     9181 ttcttacacg ctgccgtaca ataataagtt gtcaacaatg ataaggtatt aggtgatata
     9241 aaattcagta attccatggc taattattca cttaagagtt taaactcttt caaaatatta
     9301 cttatatggc aaatatactt tatttttgtt acagccaaac ggttaaacac gaaattttaa
     9361 tctaattata caattttatc aatgtgaata acaacttaca aaattataat tttattagat
     9421 tagaaaggaa gtagcattca tagccctcac attctacatt tgtagaaaca gattcaatca
     9481 aaacaaaaaa tatataatta ttagccctct atagacacac tgcataagca ggaaatttag
     9541 aatagcctcc agttggaata attaaatacg gaacagcaag aaacaaatct taaataatac
     9601 aaaacaccca attttacttt tcagggtgta aaattgggtg ttattcttgt aaacaactga
     9661 ttatcaatgt ttattgcgga gagacaggga ttcgaacccc gggtacctcg cggtacaacg
     9721 gttttcaaga ccgccgcaat cgaccactct gccacctctc caaaacttcc ttatcagaag
     9781 tgcttttcgt taaaagcggt gcaaaggtac gaagatattt taaacttgca agagttttca
     9841 ctaaaaattt aatctaatct tttcctaagg atagcaatta ataggtattt tatgttgaaa
     9901 agcataaaat agagcatatt tatgctgatt atatgaaaaa acgttgtaac tttgtgcgct
     9961 ctaaagaaaa ggataactac aacctctaat tttatcattt atggaattaa ataagatctt
    10021 taaagacggt ctttggagca cagaaatcaa cgtaagagat ttcgttagtc acaacatcac
    10081 tccgtattat ggagatgctt ctttcctcga aggacctacc gaacgcacaa aagctgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagccaat aacggagtac gctcactgga
    10201 taatgtcacc gtctcaacca tcacttctca taaagccgga tatatcgaca aagaaaacga
    10261 actgatcgtc ggtctgcaga cagacgaact tctgaaacgt gccatcaagc ctttcggagg
    10321 tatcaacgta gtcagcaaag cctgtcacga aaacggcgtg gaagtggacg accgcgtaaa
    10381 agatattttc actcactacc gcaagacgca caacgacgga gtattcgacg tatatacgga
    10441 agaaatccgt tccttccgtt cgctgggatt ccttaccgga cttcccgaca attatgcacg
    10501 cggacgcatc atcggtgact accgccgtat ggctctttac ggcatcgacc gtctgatcga
    10561 agcaaagaag gaagatttgc acaacctcac cggtccgatg acagaggccc gcatccgcct
    10621 gcgcgaagaa gtggcagaac agatcaaggc actgaaagac atgaaagtga tgggcgaata
    10681 ctacggtctc gacctgagcc gtcccgctta cacggcacaa gaagccgtac agtgggtata
    10741 tatggcttac cttgccgccg tcaaagaaca agacggtgcc gctatgtcac tgggtaacgt
    10801 ttcttctttc ctcgatatct atctggaata tgaactgagc aaaggaacca tcaccgaatc
    10861 attcgcgcaa gagctgatcg accagtttgt catcaaactg cgtatggtcc gccacctgcg
    10921 tatgcaatca tacaacgaca tctttgcagg cgacccgacc tgggtaaccg aatctctggg
    10981 cggacgtctc aacgacggac gtaccaaagt gacaaagacc tccttccgtt tcctgcagac
    11041 attgtacaac ctcggccctt caccggaacc gaacctgacc gtactctgga gcccggaact
    11101 tccggaagga ttcaaagaat tctgtgcaaa ggtttctatc gacacttctt ctatccagta
    11161 cgaaaatgac gacctgatgc gcgaagtacg tcagtccgac gactacggaa tcgcctgctg
    11221 cgtatcatac caggaaatag gcaagcagat tcagttcttc ggcgcccgtt gcaacctggc
    11281 caaagccctg ttgcttgcca tcaacggcgg acgttgcgag aataccggta cagtcatggt
    11341 gaagaacatc cccgtactga ccagtgacac gctgaagttc gaagaagtaa tggacaacta
    11401 caaaaaagtg ctgaccgaaa tcgcccgcgt atataacgaa gcgatgaaca tcatccacta
    11461 tatgcacgac aagtattact acgagaaggc ccagatggct cttgtagata cgaacccgcg
    11521 catcaacctg gcttacggtg tagccggact ttccatcgcc ctcgattcac tgtctgccat
    11581 caaatatgcg aaagtaactg cccgccgcaa tgatatcggt ctgacagaag gcttcgacat
    11641 cgaaggagaa ttcccttgct tcggtaacga caacgacaag gtagaccacc ttggcgtaga
    11701 cctggtatac ttcttcagcg aagaattgaa gaaattgcct gtttacaaga atgcccgtcc
    11761 taccctctcc ttgctgacta tcacttccaa tgtgatgtac ggcaaaaaga ccggtgctac
    11821 tcccgacgga cgtgccaaag gtgttgcctt cgctccgggt gccaatccga tgcacggacg
    11881 cgacaagaat ggtgcgatcg cttctctgag ttctgtagcg aaacttcgtt accgtgactc
    11941 acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggtg ctacggacga
    12001 agaccgtatc gagaacctcg tgacgatgat ggacggttac ttcaccaaag gtgcccacca
    12061 cctgaacgta aacgtactga accgtgatat gctgtacgat gccatggagc atccggaaaa
    12121 ctatccgcag ctgactatcc gcgtttccgg ctatgccgta aacttcgtga agctgagccg
    12181 cgaacaccaa ctggaagtta tcagccgtag cttccacgaa cgtatgtaat ctattactct
    12241 atatgatgat aaacgtacat tcatacgaaa gtatgggaac attcgacggg ccgggcttac
    12301 ggctcgtcgt ttttcttcaa ggatgcaact tccgctgcct ctattgcgcc aatccggata
    12361 cgatagcagg aaagggaggc acgcctaccc caccggaaga aatcgtccgc atggcaatga
    12421 gccagcgccc cttcttcggg aaacgagggg gaatcacttt ctccggaggc gaaccgacgt
    12481 ttcaggcgaa agcactcgtc ccgctggtcc gcgaactgaa agaaaaaggc atccatgtct
    12541 gtctggacag caacggagga ctttggaacg aagacgtaga agaattattc agactgaccg
    12601 atcttgtgtt attggatata aaggaattca accccaaccg ccatcagacg ctcaccggaa
    12661 gaagcaacga gcaaaccatc cgcacggccg cctggctgga agaacaggag aaacctttct
    12721 ggctacgcta cgtgctagtg cccggataca gcgattttga agaagacata cgcgcactgg
    12781 gagaagcact cggaaaatac aagatgatcc aacgggtgga aatactgcct taccatacac
    12841 tgggcgtaca taagtacgaa gcgatgggac aggaatacaa gatgaaaggg gtaaaagaaa
    12901 atacccccga acagcttgaa aaagctgcgg aggtattcaa agagtatttc actacggtgg
    12961 tagttaatta atggagaatt ctccaatgac ctcaaagcaa gggcattctt taatccgttc
    13021 ccaaggatct acgatcccat tatagttggt gtcgggactt aaatcccgat gccctactac
    13081 tttagcttcc ggataacgct gcaacaattc gtgtaccaag cgatgtagcg cctccttctg
    13141 acggggtgta cgcgtatccg cagcttttcc attctcatcc agaccgccct cataacatac
    13201 acctaagctg atcgcattat agccacgtgc atgagctccg accgtatctt catcccgcat
    13261 cggctcaatc tcgcccgact tgcgtatata ataatgatac ccccagcacg aaaagccacg
    13321 ataacggtga gccgtatcca catcctttgc cgtaaagtcg caatcgacac gggtggcgga
    13381 acaatggatc acaatcagac taatctttct catgttcctt ttccctttcc gtcgttttca
    13441 ctttgcacac ctccttacaa gtagtatgat agcgcacttc tctcaccacc ctgtcccgct
    13501 ttctctttcc gaagaaagga atcagataca tgatcacatc taaaatccga cttactattt
    13561 ctttcatctt atcaaaatat taatggaagt tattctaatt cgttattacc ttgacccgtc
    13621 tgccaattat accgtagggt ccggagcctc ttcatcaccg gagccatcac caccggaatc
    13681 cggattcttg tcagggtctt ctcccccgcc atcgcctgca cccgcctgcg ccaccgcacg
    13741 agtctgcact tgctgataac tcagaatctt catcaactcc gccagcgtct taccggggcg
    13801 gaaaataaga tgcgccccct taatcattga accggaaaat tccttgaccg atgccgcacc
    13861 ttcactgttg agtcctatct gcaaactgcc caaatcgccc agtctcgcaa ttcttcctgc
    13921 cttcaacgca cgcttcactt cgtaaagaat acccgaaata gccgcacgta catccgtttc
    13981 cgtacaagta gaacgactgg tgatcgcttc gcacaactct tcaaagtcca actctcccga
    14041 cgcctgcgcc tgtgcataat actttgccgg ttcgctcttt tttgcaggat tcttgcgcgg
    14101 caccactgaa taagatactg tcattgccat aataaaataa ttttaaagtt tataatacat
    14161 aggatgcatc cccttcttgt taacagcaca aagataagga tagccggaca agccatattc
    14221 cccaacgaag tttcttgatt cccaacgaat aaaaacgaag tcaaaccttt gaataacaag
    14281 gaattttatg taactttata gcataaaaca agaagaaaac atcatgaatt acaaagaaga
    14341 ttctttcctt atccgcacct ataccaaagc ggaactggct cacctttaca atccccatgt
    14401 ctgcctcaaa gttgctttac aaatacttcg tcgttggatt atttacaacc tccctctcct
    14461 gcacgaactc gaacaggaag gctaccgcgc acgcaaccgt ctcctttcgc cgaaacaagt
    14521 ggcaactatc atacactttt tgggcgaacc gtagtaactt attgccattt tatacaaagt
    14581 tcctttacac atttccgcaa agaagttcct ttgcatcgac aaacaataat caaaataaaa
    14641 atgaaacatt tcaccatatt tcaaggtttc tactacgcaa tagcagagat gaccgaagaa
    14701 gaaatagtgt ccactatcgg cagttttacc taccgggaaa aagtcgaaga aatacgccgc
    14761 atctttgcag agcaaggaga aaaggctgcc aatgagaaga aaaaagaatt gccggcaatc
    14821 gccttctccg ccagctaccg aggaaggcgt accaaagtga acctcgtcaa atatctggga
    14881 cacatcgtga tagacatcga ccacctcagc aaagaagaat tggcacgcat cctccctatc
    14941 atcaagagat gcgattacac ccgcatcgcc tttatcagcc ccaaagggat gggcgtgaaa
    15001 atcatagtac gcgcatgcca tccggatgag acattgcccg aaacccttca ggaaatagaa
    15061 gacttccatc atgcagctta caccagactc gtttcttttt acaccgaact ctgtcagata
    15121 gaaatcgaca cctccggtca ggatgtggca cgcacttgtc tgttctctta cgatccggag
    15181 atttatttca atccgaacgc tgacgctttt cttgtagatc aacctcaggc atcctacaag
    15241 gtttcaaatc gtaaaaatct ctccggcagt aaacaacaga ctcctccgga cggccccccg
    15301 acgaatgaag acacagcgct caacgcccat tccgccaacg cttctctggt gctgacttta
    15361 acctactatc acaacaagtc cgaaaaatac atagtgggca accggaacaa ttatctgcac
    15421 catctctcat gtaccttcaa tcgctacggc attccgcagg aggaagcatc cgcctttatc
    15481 aaaagccagt ttacagactt tccggcggac gagacagcct ctttgatcaa tagcgcctac
    15541 gctcataccg acgaatttaa tacctgtaag ctaaatggca cgcagaaacg aatattacgg
    15601 atagagcaat atatcagcga gcactacgaa acacgctaca acgaagtgct gcatatcatg
    15661 gaatatcgca gaaggcatcc cgacaccgag aaaccggagc ctttccgcat cttggatgag
    15721 atgatggaaa acagtatctg gatagaaatc aacgaactgg gatatgcctg cactgtcaaa
    15781 acaatcgaaa atctgattta ctccgatttc agccagtcgt atcatcccat tcgcgagtat
    15841 tttgaattac tgcccgaatg ggacggaacc gactatatcc gtatcctggc ggatagtgtc
    15901 cagacgagtc atcaggagtt ttgggcggaa tgcctggaac gttatctggt ggcgatgtgc
    15961 gcagcggcta ctcaagagaa tattgtcaat cacacggtac ttctgctatg cagcgagata
    16021 cagaacatag gaaagactac ctttatcaat aatctcctgc ctcccgaact gcgtgcttat
    16081 ctctctaccg gactaatcaa ttcgaacaat aaagatgatt tagccaaaat aacgcaggcc
    16141 atgctgatca atctcgacga gtttgaaggg atgagcggtc gggaactgaa tgcattcaaa
    16201 gatttggtaa cgcgcaaagt gatcagtttc cgtctgcctt atgcacgccg ttcgcaaaac
    16261 ttccctcata cggcctcttt tgcaggaacc tgcaattatc aggaagtgct tcacgacacg
    16321 acaggcaacc ggcgtttcct ttgttttcat ccttattcca tccaatttat taccatcaat
    16381 tatgcgcagc tctatgctca gatcaaatat ctgctgaata agccgggata tcaatactgg
    16441 ttcacgcaag cggacaatga acggcttgaa gagaataacg aggctttcat ctttcattca
    16501 ccggaagaag aaatggttct tacgcatatc cgcaagccgg aacgtttcga gaaggtttat
    16561 tatctgactg tcagtgagat tgcggaacta atacgtgagc gtaccggtta tcagtattcc
    16621 atcggatcaa aaatacagtt ggggaaggtg atgactaagc accattttga atctaaaaaa
    16681 ggaaataacg ggcgccgata tgccgtattt attatagata tcgagcaggt aaaatcaaac
    16741 aggctgtatg aatagaagcg ggaaagcctt gtgaataggg agtgtaattt aaactctgtc
    16801 tggtttctat ttcttttaaa tcacaacaa
//
