LOCUS       c00015_gnlPro..        14926 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OOKOLCIJ_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:07:45
            Original ID  :: gnl|Prokka|OOKOLCIJ_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 35120
            Orig. end    :: 50046
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14926
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[45120:49188]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14068
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..14926
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14926
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(1423..1755)
                     /locus_tag="ctg15_30"
                     /transl_table=11
                     /translation="MAGMEQEPERGGRCLRCFKMRLQETARYAHEHGFPVITTTLASSR
                     WKSLEQIEEAGRYATAPYPDVTYWEQNWRKGGLSERRIAIIKEYNFYNQQYCGCEFSMR
                     KEEKEE"
     CDS             complement(2023..3621)
                     /locus_tag="ctg15_31"
                     /transl_table=11
                     /translation="MKLEKWKNKWKKWSNLRKWQIWKLKLIDARLYFVSIFVGLLTGLV
                     AVPYHYLLWYFFDVRKTFFTAHYPWYWHVLLFFILWGILIFVASLVKRMPLIAGGGIPQ
                     TRAANNGRIRYEHPFKELVAKFCGGVLALSAGLSLGREGPSVQIGSYIGTLISRWGHIL
                     KGERKQLLAAGAGAGLSAAFAAPLSSSLLVIESIERFDAPKTAITTLLAGVVAGGVASW
                     MFPTTPYHLISAVVPGLSFIRQAELYIIFAALMAVIAKFYSLIVPFFQERIPAMKLSIP
                     VKMLYLLTIAYAISLTETNLTGGGEQFLMMQGMNGTHDIRWLTIMMLIHFVFTLFSLSS
                     GLPGGSFIPTLVTGGLLGQIFGLVLVQRGWIGYENVSYMMLIGMVAFLVAVVRTPLTAI
                     VLITEITGHFEVFYPSIVVGGLTYYFTELLQIKPYNVLLYDRMFRSHNPESSEEAGARY
                     HLFVEIMDGSYFDGKEVDTLALPNHCIIRSIHRNRKNLLPQGQTLVPGDQVEIEIDAQD
                     IEKLYEPLVSMANIY"
     CDS             complement(3654..3983)
                     /locus_tag="ctg15_32"
                     /transl_table=11
                     /translation="MRELFKALSELETRLMEQYGVSLNEAMALCCIGGDTLTASVISEN
                     TGLSASHTSKVIRSIEEKELIVRNLGDKDKRQMHFTLSDKGHECLEALKANEIEISELL
                     KPLFK"
     CDS             complement(4017..6395)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_33"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-62, bitscore:
                     203.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 1.5e-13, bitscore:
                     42.5, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLP
                     YYIGGVIAEREKLFVQTPEAFGKRFNIDVRTRSEVIAIHSAEKTVDIRTSDGKTYTESY
                     DKLLLSPGASPVRPPLPGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFIGLE
                     MAENLQEAGAEVAVVEMANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNG
                     LEVVFKSGERLPADMVLLSIGVRPNTSLATEAGLEIGEMRGIKVNDYLQTSNEHIYAVG
                     DAIEFRHPLTDRPWLNYLAGPANRQARIVADNMVFGNKVTYEGAVGTSIAKVFDMTVAA
                     SGLPAKRLKQAGIDYLSATIHSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGV
                     DKRIDEFSQVIKHNGAVYDLMALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWR
                     ELQAADLSKVTLVDVRTPDEFALGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLR
                     GYLASNILLQNGFGEVKNLIGGLKLYKAATAPLPEPEEFSNSGSSSSDSSKVDHSEHSK
                     DSAEAYTIASSVIPSMKAIKVDACGISCPGPIMKLKKSMEELADGERLEIVATDAGFPR
                     DAEAWCHTTGNRFVSVKSGAGKYEVIVEKNTPQSSSSEVCREDKGKTFILFSDDLDKVL
                     ATFVLANGAAATGKKVTIFFTFWGLNAIKKLDKPVVKKDIWGKMFGMMLPSSSLKLKLS
                     KMNMGGMGVKREELLDHVTIGGVATYMNRAEQANVNLFI"
     CDS             6632..7987
                     /locus_tag="ctg15_34"
                     /transl_table=11
                     /translation="MLSKIDLTQGGITGTLLRFTLPMIIGSLLQQCYNIADTLIVGQCI
                     GSGALAAVGSAYTLMVFLISILLGLSMGSGTVFSLQYGAGRTDSLRRNIYVSALLIGTV
                     TLILNIAAFVWIHPILRLLQIPKDIYGMMYDYLWIIFWGIGFTFIYNFYAALLRAIGDA
                     VTPLWFLAVSVVLNIGLDLFFILQLDWGIKGAAIATVAAQGVSALGIMGYAYVKYPELR
                     LHRNDLHFDRHCLKEITSFSALTCVQQSVMNLGILMVQGLVNSFGTVVMAAFAAAIKID
                     SFAYMPVQEFGNAFSTFIAQNFGARKEERIRKGVKSALITTVLFSLVISILVFLFAKPL
                     MLIFVRPHETEILNIGISYLRIEGAFYCGIGILFLLYGYYRAIRMPGMSVVLTVVSLGT
                     RVALSYWLAGIPAIGVIGIWWSIPIGWFIADVIGIIYYKQLKKETAKEVPAP"
     CDS             complement(7950..9650)
                     /locus_tag="ctg15_35"
                     /transl_table=11
                     /translation="MMVGLFVVGGAIFQTGLAKMISSHILKLAGKSELKLFLLVMLVTS
                     AIGAFVSNTGTVALMLPIVVSLAVSANMNPSRLLMPLAFASSMGGMMTLIGTPPNLVIQ
                     NALTSAGFPPLSFFSFFPVGIICVAVGTLVLLPLSKWFLSKRGKNGDNNVHSGKSLKQL
                     VKEYGLSSNLFRLRVVGDSRLHGKTIIELDIRRKYGLNILEVRRGDMSQHRFLKTITQK
                     LADPGTVLQKEDILYVTGDFEKIKLFAEDYLLEMLDEHTTEEAKNSANSLDFYDIGIAE
                     IVLMPSSNLINQTIKGAGFRDKFNVNVLGIRRKKEYLLQDLGNERIHSGDVLLVQGTWN
                     NIARLSKEDADWVVLGQPLAEAAKVTLDYKAPVAAVIMVLMVAMMVFDFIPVAPVTAVM
                     IAGILMVLTGCFRNVEAAYKTINWESIVLIAAMLPMSLALEKTGASEYISNSLVSELGT
                     YGPLALMAGIYFTTSLMTMFISNTATAVLLAPIAMQSATQIGVSPVPFLFAVTLGASMC
                     FASPFSTPPNALVMPAGQYTFMDYVKVGLPLQIIMGIVMVLVLPLLFPF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_36"
                     /sec_met_domain="HBT (E-value: 3.3e-14, bitscore: 44.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEEITCKPDYSNSMAEHLGIRFLPPTENAVHAEMPVDHRTSQPF
                     GMLNGGASLALAEIVAGHGSMSLCREGEYACGVQVSGNHLSAVPVGGKVFATGKLIHRG
                     RSSHIWNIDITTPQGELVSTVRVVNFILKKK"
     CDS             10405..11574
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_37"
                     /sec_met_domain="Chorismate_bind (E-value: 6.7e-57,
                     bitscore: 184.4, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLPDIHTQKLLDCLTHSHLGFALYRLPWTDECYLVLQTSGDVEQ
                     LADIQELNEKKGFVVAPFRISEEHPLVLIRPDVTAYDWNEISEALSSLECVDTLLTCKS
                     RQNELSPFVSEETDKEQYTRAFGRFITPLQEKQFQKLVLSRSSARHIGDDFSPLGAFVR
                     ACNNYPRMMIYLCHTPASGTWLGSTPEILLSGQGKEWHTVALAGTMPMQDEVMPTNWDK
                     KNQEEQGYVADYIRRIAKKFGNKMTEKGPYTARAGQLVHLKTDFYFLLKNTDHIGDLLQ
                     ELHPTPAVCGLPKEEAFRFILNNEGYDRSYYSGFTGWLDTEGHTDIYVNLRCMEIKPGE
                     AILYAGGGILASSEVESEWVETGDKMNTMRSILHPDFISKQMETIKVEE"
     CDS             complement(11763..11936)
                     /locus_tag="ctg15_38"
                     /transl_table=11
                     /translation="MGLGQGLSVHLSYPGGGAVGRNDNQRYLLVKSFGYGRVQVQQGRT
                     GGAAYCGRTSPL"
     CDS             complement(11949..12482)
                     /locus_tag="ctg15_39"
                     /transl_table=11
                     /translation="MFARGMIAQVFLQLLGYDMSAVGNQYFGGHVFLALRRHGINGGVE
                     ILDRNAGDGLVAQMFRQPGEMFIKRFHIFFLEQVNQIHLAYHDHALVVLVQPFDQFLIV
                     TVVHAQSLITGDDTCLGKCFGGEAVDGFGNGYIDMYGSFAVVGGFQYGFVDEAVAKPFV
                     FLCMYFGQVDRHLD"
     CDS             12801..13247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_40"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-07, bitscore:
                     22.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNGIEGSLSTAIGYAAASSKLNFIIIGDLSFFYDMNALWNQNYGA
                     NIRILLLNNEGGEIFHTLPGMDKSSRSREFITAEHYTTAKGWAEERGFIYMKVTGEEEL
                     EEAMQPFTSPETRMQPMLLEVFTDKEKDTTLLREYYHGLKNKNE"
     CDS             13427..14068
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_41"
                     /sec_met_domain="ECH_1 (E-value: 2.2e-71, bitscore: 231.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVLTGAGDKAFCSGGDMHVKGHGGYIGTDGVPRLNVLDVQKQIRS
                     LPKPVIAMVNGYAIGGGHVLHVVCDLTIASENAIFGQTGPKVGSFDAGFGSSYLARIVG
                     QKKAREIWFLCRQYSAQEALEMGLVNTVVPFDRLEDETVAWAEKMMEHSPLALRMIKAG
                     LNAELDGQAGIQELAGDATMLYYMTEEAQEGGKAFLEKRKPRFQDYPKFP"
     CDS             14089..14472
                     /locus_tag="ctg15_42"
                     /transl_table=11
                     /translation="MDIEEFRKYCLSLGDVSEKMPFGKFAARYDSILAFYVYGHMFCFI
                     DIDNFTFVNVKSTSDEIEYIKERHVSVGNPINQSLKHWLQLNFDGDIPDTSIYTWVQRA
                     FEIVRDKYTKPTTHKKKCSKPKL"
     CDS             14451..14876
                     /locus_tag="ctg15_43"
                     /transl_table=11
                     /translation="MFQTQIIKKQLHFKQPAGTSRGVYTTRDVWYILLTDIGSCHYGVG
                     ECAPLPALSCDDIPSYDEVLATACKNLEKNGEIDREALLPYPSILFGMETALLHFRARS
                     LQFWHTPFSKGKEGIPINGLIWMGNFDEMYRRIGEKM"
ORIGIN
        1 attgcggcaa agaagttttc gtcgattccg taagatattc ttgtaaaaga gcggactggc
       61 ggcctatctc tacaaactgc tcgtctattt tattctgcaa ttgctgttca cgccggatag
      121 cgtcctgatt ttgcttcaca atggtaaggt acagcttatt ttttctgtaa tataagtaat
      181 atagtaaaga ggcagctatg aagatacaga taaatccggc tataagcaat tgcatcttat
      241 tttccttttc caataattcc agacggtttt gttttatctc gttttcctgc cgttccatat
      301 cgtattttgc acgtatctcc cccacggcac gttccttttc cgcattatat aagctatctg
      361 tttccagctg atagagctta tgatacttca acgcctctac cagcatacca tcttcttcat
      421 aacatcggga taaagcctgc aacaggtcac ttcgataaat ggcattagcc tgttggtaag
      481 acagttctat tccggctttc agcatccaga cagcccggtc atactgatga tgctccatta
      541 aaatttcggc atagcccaaa taggaattca tcacagaaga aatatttccc tgttctttca
      601 aatccaaagc cttccggaaa aagcccagcg cttcatcatc tttattcaat ttatgcagaa
      661 tatatccata aagattgtaa acgtttgatt gatcataaaa gtcattctgc accatggtga
      721 actccgcctc ctgaatatat ttcaatgctg tattatagtc actcttcaaa taatacatat
      781 aagcggtatt ggttgaacca ctataaatca gataaggatc tttccgttca tgtcccagtt
      841 cataacattc aagggcatat ttcaatcctg tgctatcatt tttcaaataa taaataccgg
      901 caatattaga aagtaaaatg gaatagagtc tgtcataatg acaacgtctt gcagcttcaa
      961 ctcctttgaa gaaataagta agtgaacgat aatagtcttt ttggacattc gatgcataaa
     1021 gtcccagacc attatatacg gaacataagg cggaatcatt tttattactt tcacctatca
     1081 gcctggcctg ccctaaatga ctataagcct cctttacatt tcccttcatc atatgggcct
     1141 gccccagaca aatatgagaa taaattacag cgccattgta atcccgttca ttataaccca
     1201 tctcaaacaa ttgtcgacca taaaagatag cctgatcata atctgcttta ttcagataga
     1261 gaaaactaac tttccgaagc gcttctttat ctttaggata ctttttcaga tactccaact
     1321 gtacattaat ggcattattt atttcttctt gcgcctctga aacaacgggc aagagtccca
     1381 ataacattac aaccacccac agtttaagca tcctcattcc tgtcattctt ccttttcttc
     1441 tttccgcata ctgaactcac agccacaata ttgctgatta taaaaattat attccttaat
     1501 gatagcaatg cgacgctcgc tcaatccacc tttacgccag ttctgttccc aataagtgac
     1561 atccggataa ggggccgtag catatcggcc cgcttcctct atctgctcca aacttttcca
     1621 acggctggaa gcaagcgtag tagtgataac cgggaatcca tgttcgtgag cataacgtgc
     1681 ggtttcctgc agtcgcatct tgaaacaacg caagcaacgg cctcctcttt caggctcttg
     1741 ctccattcct gccattcgac aacgccaggc atcatgatca taatcggcat ctataatttc
     1801 caatcccaag gactgggcgt accgcgtaca ttcgtccttg cggataatgt attcctccaa
     1861 cggataaata ttgggattac aataatagat aaccggagtg acaccatgct gcatcaagca
     1921 ctctatgatg gctgatgaac aaggagcaca acaagtatga agcaacacct tgtcggctcc
     1981 tcccggaact tcaagctgga atttcttttt catacggcaa atttaataga tatttgccat
     2041 actgaccaac ggttcgtata atttttctat atcctgcgca tctatttcta tctccacttg
     2101 atcaccggga accagggttt gcccctgagg aagtaagttt ttacgattcc gatgtatact
     2161 acgaatgata caatgattag gtaaagccaa tgtatccact tcctttccgt caaaataaga
     2221 cccatccatt atctcgacaa aaagatgata gcgggcacca gcctcttcgg aagactccgg
     2281 attatggcta cggaacatcc tgtcatacag caatacattg taaggtttta tctgtaacaa
     2341 ttcggtgaaa taataagtca atccacctac cacaatggaa ggatagaaca cctcgaaatg
     2401 accggtaatc tccgttatca ggacaatagc agtcaaagga gtacgcacca cagccaccaa
     2461 aaaagccacc atcccgatca gcatcatata actcacattc tcatacccta tccatccgcg
     2521 ctgtaccaat accaacccga agatttgtcc caataatcct cccgtaacca aggtaggaat
     2581 gaaacttcct cccggcaaac ccgaagaaag agaaaacagc gtaaaaacaa aatgaataag
     2641 catcatgata gtaagccacc ggatatcatg agttccattc attccctgca tcatcaaaaa
     2701 ctgctctccg ccacctgtca gattcgtctc tgttaacgat atggcataag ctatggttaa
     2761 taaatacaac atcttgacag gaatggagag tttcatggca ggtatccttt cttgaaagaa
     2821 aggaacgatg agcgaataaa actttgcaat gacagccata agggcggcaa agataatata
     2881 aagctccgcc tgacggataa aagataaacc aggaacgacc gcactaatca gatgataagg
     2941 agtcgtgggg aacatccaac tagccactcc tccggctacc acgccggcca acaaggtagt
     3001 aatagcggtt ttaggtgcat caaaacgctc gatggattct atcaccaaca aagaagaaga
     3061 caacggagca gcaaaagcgg cagacaagcc cgcaccagct ccggcagcca gcaattgttt
     3121 ccgttcccct ttcagaatat gtccccaacg agagataagt gttcctatat aagaccctat
     3181 ctgaacagac ggcccctcgc gtcccaaaga cagccccgca ctgagagcca acacccctcc
     3241 gcagaattta gctaccagtt ctttaaaagg atgctcataa cggatacgac cgttattggc
     3301 cgcacgtgtc tgaggaatcc cacctccggc tatcaatggc atacgtttta ccaaagaagc
     3361 gacaaagatc agaatccccc ataagataaa aaacaacaat acatgccaat accacggata
     3421 atgcgccgta aaaaaagttt tccgcacatc aaagaaatac cagagaagat agtgataagg
     3481 cacagcaacc agtcccgtaa gcagccccac gaatatgctc acgaaataca gacgggcatc
     3541 aatcagcttc agtttccata tttgccattt gcgcagattg ctccacttct tccatttgtt
     3601 tttccatttc tccagtttca tatccggaat aaacaaatgg aaaagagaag ggtttattta
     3661 aacaatggct ttaatagttc cgatatttct atttcatttg ctttcagcgc ttccaaacat
     3721 tcatgccctt tatcggataa agtaaaatgc atctgccgtt tatccttatc ccccaaatta
     3781 cggacgatta attctttctc ttcaatggaa cggatgacct tagaggtatg cgaagcagac
     3841 agacctgtgt tttccgatat cacactagcc gtcagcgtat ctccgccaat gcaacaaagt
     3901 gccattgcct cattcaatga cactccatat tgttccatta agcgggtttc aagttcagag
     3961 agagccttga acagctctct catgacacat attgatttta ttttctccat gcatatttaa
     4021 ataaacaagt ttacattcgc ctgttcggca cggttcatat aagttgccac tccaccaata
     4081 gtcacatgat ccagcaattc ctcacgtttc acacccattc cgcccatatt cattttagac
     4141 aacttcaact ttaaagaact ggaaggcagc atcatgccga acatcttccc ccagatatct
     4201 ttcttcacca caggtttgtc cagcttcttg atggcattca gcccccagaa agtaaagaag
     4261 atggttacct tctttcccgt agccgccgca ccgtttgcga gtacaaaagt agctaaaact
     4321 ttgtccagat catcactgaa cagaataaaa gttttccctt tatcctcccg gcaaacctcc
     4381 gaggaagaag attgcggagt atttttctca acaattacct catactttcc tgctcctgat
     4441 tttactgaga caaaacggtt cccggtagta tgacaccatg cttcggcatc gcgggggaag
     4501 ccggcatccg tagcgacaat ctccagacgt tcgccgtctg ccagttcttc catactcttc
     4561 ttcagcttca tgataggacc gggacaagat ataccacaag catccacttt tattgccttc
     4621 atagaaggaa tgacggaaga ggcaatagta taagcttcag cagaatcttt actgtgttca
     4681 gaatgatcaa cttttgaaga atcagaactt gaagaaccgg aatttgagaa ctcctccggc
     4741 tcgggcagag gagccgttgc cgctttatac agtttcaaac ctcctattaa attctttact
     4801 tccccaaaac cattctgtaa caatatatta gaagccaaat accctctcaa ccctactcca
     4861 caatacaaat agaccggctt atcctgagga atctctttca tcctttcgcg catatcatcc
     4921 aaaggaatat tgacagcccc tttcaaagca ccgagtgcaa attcatcggg agtacggaca
     4981 tcaaccaacg taactttact caaatcggca gcctgcaact cgcgccaata aagaggcttc
     5041 atctttccgc tcagtatatt tccggctaca tatccggcta ctgctacagg atctttagcc
     5101 gaagagaaag gaggagcata tgcctgctcc aaagccatca agtcataaac agctccgtta
     5161 tgcttaatca cttgcgagaa ttcgtcaata cgtttgtcca ctccgttata ccccacaatc
     5221 tgcgctccga gtaatttccc attcacagga gagaaagtta ttttaatgga catctgtaaa
     5281 gcatcaggat aatatcccgc atgggaaccg gaatggatgg ttgccgacaa ataatcaatg
     5341 cctgcctgtt tcaaccgttt tgccggaaga cccgaagcag cgacagtcat atcaaaaact
     5401 ttggcaatgg aagtaccgac agccccttcg tatgtaacct tatttccaaa gaccatgtta
     5461 tctgccacaa tacgcgcctg acggttggcc ggacctgcca gataattcaa ccacggtcta
     5521 tcagtcagtg gatgacggaa ctcgatagca tcgcccaccg cataaatatg ctcgttggaa
     5581 gtctgcaagt aatcattaac cttaataccg cgcatctccc ctatctccag tccggcctct
     5641 gtcgccaatg aggtattggg acgtaccccg atggataaca acaccatatc ggcaggcagc
     5701 ctttcgcccg atttgaaaac aacctccagt ccgttgaccg tgcgttcgaa agaagccacc
     5761 gccttttcca gatagagatg tactcctttc tgcaacaagt gctcgtgcac caaagaagcc
     5821 atagagaaat caataggagc catgacctga tttgccatct ctacaaccgc cacttccgca
     5881 ccggcttcct gcagattctc cgccatctcc aacccgatga atccggcccc gatgattacc
     5941 gcccgtttca ccttatgctg ctgcaagtaa ctcttgatag catcggtatc attcacatta
     6001 cgtagggtaa aaatcccttc attgtcaatg cccggcaagg gaggacgaac aggcgacgca
     6061 cccggagaaa gcaataattt gtcataactc tccgtataag ttttcccgtc ggaagtacga
     6121 atatccactg ttttctcggc agaatggatg gctattacct cggaccgggt acgcacatct
     6181 atgttaaaac gtttcccaaa agcctccgga gtctgtacaa acaatttttc ccgctccgca
     6241 atcacacctc ctatataata aggtagacca caattggcat acgaaatgta ttctcccttc
     6301 tcgaacaaaa tgatttccgc ctgttccgtg tttcttctga tacgtgcggc agcagttgca
     6361 cctcctgcta cgcctcctat tactatatac ttcataatta aactatttta tttgatttaa
     6421 tattttccaa tggaaacttt atgcaaacat acatgatatt tcttataata aaaagtttcc
     6481 tatggaaaat attatcaagt taactctttt taaggagaaa gaacattccg ggtattaaat
     6541 agacaatctt tattgttgtt tgatatttta ttccctacct tcgcaataaa tttcaaaata
     6601 aataagaaat tgaatcgaac agacacgcat catgttatct aaaatagact tgacgcaggg
     6661 aggtatcacc ggcactctgc tacgttttac cttacctatg attataggct cactgctaca
     6721 acagtgttac aatatagccg acacgctgat tgtaggacaa tgtataggtt ccggcgcatt
     6781 ggctgccgtc ggttccgcct atacgctgat ggttttcctc atttccatcc tgctgggatt
     6841 gtccatggga agcggaaccg ttttttcctt gcaatatgga gccggacgaa cggattccct
     6901 acgccgtaac atctatgtat ccgccctgct gatcggtaca gtaacattga ttctaaatat
     6961 agcggctttc gtctggattc atcccattct caggttattg cagattccca aagatattta
     7021 tggcatgatg tatgattact tgtggattat cttttgggga atcggcttta cctttatcta
     7081 taatttctat gcggcattac tgcgtgccat aggagatgcc gttactcctc tttggtttct
     7141 ggcggtttcc gttgtactga acatcgggct ggatttattc tttatcttgc agttggattg
     7201 gggaatcaag ggagcagcca tcgccacggt ggccgcacag ggagtatccg ctttgggaat
     7261 tatgggatat gcctacgtga aataccccga actgagatta caccgcaacg acctgcattt
     7321 cgaccgtcac tgcctgaaag agatcacttc gttctccgca ctgacctgtg tacaacagtc
     7381 ggtgatgaat ctgggcattc tgatggtaca aggattggtc aatagttttg gcactgtagt
     7441 catggccgcc tttgcggcag caataaaaat agactcgttt gcctatatgc cggtacagga
     7501 attcggaaat gccttttcca cctttattgc ccagaacttc ggagcgagaa aagaggaacg
     7561 gatccgcaaa ggagtgaaaa gtgccttgat taccaccgtt ctcttctctc tggtcatttc
     7621 cattctggtc tttttattcg ccaaaccatt gatgctgatt tttgtccgcc cccacgaaac
     7681 ggaaattctg aacatcggta tcagttattt acgcatcgag ggagcgtttt attgcggaat
     7741 cgggattttg ttcctgttat acggatatta tcgtgccatc cgtatgccgg gaatgtccgt
     7801 agtgctcaca gtggtatcgt tgggaacccg tgtagccctt tcctattggc ttgccggcat
     7861 tcctgccatc ggggtcatcg gaatctggtg gtctattcct atcggatggt ttatagcgga
     7921 cgtcatcggc atcatatatt ataaacaact taaaaaggaa acagcaaagg aagtaccagc
     7981 accatgacaa tgcccataat aatctgcaac ggcagcccta cctttacata atccataaag
     8041 gtatattgtc cggcgggcat caccagcgca ttgggcggag tggagaatgg agaagcgaaa
     8101 cacatacttg cccccagtgt caccgcaaag agaaaaggta cgggacttac ccctatctgt
     8161 gttgcacttt gcatcgcgat aggagccaga agcactgcgg tagccgtgtt gctgataaac
     8221 atcgtcatca gggaagtagt gaaataaata cccgccatca gcgccaacgg tccgtatgtt
     8281 cccagttcac tgaccagact gttcgaaatg tattcggaag cccctgtttt ttccaatgcc
     8341 agcgacatag gcagcatggc cgcaatgagt acgatgcttt cccagttaat ggttttgtaa
     8401 gccgcctcca cattgcggaa acatcctgtc agtaccatca ggatacccgc aatcatcacc
     8461 gccgtcaccg gagctaccgg aatgaagtcg aacaccatca ttgccaccat cagcaccatg
     8521 ataaccgcag ctaccggtgc tttgtaatcc agcgtgacct tcgcagcctc ggccagcggt
     8581 tgtcccagta ccacccagtc ggcatcttcc ttgctcagcc gggcgatatt gttccatgta
     8641 ccctgcacca gcaacacatc cccgctatga atccgctcat tgcccaagtc ctgcaacaaa
     8701 tattccttct tccggcggat acccagtaca ttcacattaa acttatcacg aaagcccgcc
     8761 ccctttatcg tctggtttat cagattggag gaaggcatca aaacgatttc agcaatacct
     8821 atgtcataaa aatccaatga attggctgag tttttcgctt cttcggtagt atgctcgtcc
     8881 agcatctcca gcagataatc ttcggcaaac aactttattt tctcaaaatc ccccgtcaca
     8941 tacagaatat cctctttctg aagaaccgta ccgggatcgg ccagcttctg agtaattgtt
     9001 ttcaggaagc ggtgttgtga catatcccca cgacgcacct ccagtatatt caatccatac
     9061 ttgcgccgga tatccaactc tataatcgtc tttccatgca gccgggagtc accgaccacc
     9121 ctcaaccgga acaaattact ggatagccca tattccttca ccaactgttt cagggatttg
     9181 cccgaatgaa cattgttgtc tccgtttttc ccccgtttcg aaagaaacca tttactgagc
     9241 ggaagcaaca ccaaagtacc cactgccaca caaataatcc ctaccggaaa aaaagagaag
     9301 aacgaaagcg gaggaaaacc ggccgaagtc aacgcatttt gaataacaag gttgggcggc
     9361 gtaccaatca gtgtcatcat acctcccata ctgctggcaa acgccaacgg cataagcaaa
     9421 cgactgggat tcatgttggc actgactgcc agactgacca cgataggcaa catcagagcc
     9481 accgtacctg tgttgctcac aaaagccccg atagcagaag tcaccaacat tacaagcaag
     9541 aataatttca attcactctt acccgctaat ttcagaatgt gtgaactgat cattttggca
     9601 agtcccgtct gaaaaatcgc tccgccaacc acaaacagcc ccaccatcat aatgacgacc
     9661 gaattggaga atccggacaa agcctcgtca ggcgtcaata tctgaaaaat caacaaagcc
     9721 actaaagcac aaagagccac aagatccgac cgtatcttgc catttacaaa aaatactgcg
     9781 gacagtacaa ggataataat cgtaatgagc ataggtatta aattattgtt ttattcattc
     9841 gttgttgcat ttgtacgaat tctttttgca aaataaaaaa tatattccga aaatagaaac
     9901 aaaccccgaa tgtttttgtt cttaaaagaa caacattagc gacattttca tctaaaattt
     9961 atgtattttt gtagccctat agaaaagaac agacatacaa atgatggaag aaataacctg
    10021 caaacctgat tattcgaatt cgatggcgga acatctgggt atccggtttc taccccccac
    10081 cgagaatgcg gtacatgccg aaatgcctgt agaccatcgt acttcacaac cctttggtat
    10141 gttgaacggc ggcgcgtcac tggctctggc cgagattgtg gcaggacatg gctccatgtc
    10201 gctatgccgg gaaggcgaat atgcctgcgg agtacaagta agtggaaatc atctgtcggc
    10261 cgtacccgtc ggaggcaaag tattcgccac cggcaaactg attcaccgcg gcagatcctc
    10321 gcatatatgg aatatagata tcaccactcc acagggagaa ctggtttcta ctgttcgtgt
    10381 cgttaatttc atactgaaaa agaaatgaat ctaccagata tacatacgca aaaattattg
    10441 gattgcctga cacatagcca cctcggtttc gccctctacc ggttaccttg gacagacgaa
    10501 tgctacctgg tattgcaaac ctcgggcgat gtggaacaat tagcggacat tcaagaactg
    10561 aatgaaaaaa agggatttgt cgtggctcct ttccggatat cggaggaaca tcccttggta
    10621 cttatccgtc cggatgtcac ggcatacgac tggaacgaaa tcagcgaagc actgtcttca
    10681 ctggaatgtg tggataccct gctcacctgc aaaagccggc agaatgaact ctctcctttt
    10741 gtttccgaag aaacggataa agaacaatat acccgcgcat tcgggcgttt catcactccc
    10801 ttacaagaga agcagtttca aaaattggtt ctgtcacgtt cttccgccag acatatcgga
    10861 gatgattttt caccacttgg cgcttttgtc cgggcctgta acaattatcc gcgcatgatg
    10921 atttacctat gccacacccc cgcttccgga acctggctgg gcagcacacc ggaaatctta
    10981 ttaagcggac aaggcaaaga atggcacacc gtggccctgg ctggtacaat gccgatgcag
    11041 gacgaagtga tgccgacaaa ctgggacaag aagaaccaag aagaacaggg ctatgtggct
    11101 gattatatcc gccggatcgc caaaaaattc ggcaacaaga tgacggagaa aggtccctat
    11161 accgcccgtg ccggacaatt ggtacacctc aagactgatt tttatttctt gttgaaaaat
    11221 acagaccata taggcgattt attgcaagaa ctccatccca ctcccgccgt ctgcggcctg
    11281 cccaaagagg aggctttccg gtttattctg aacaacgaag ggtacgaccg cagttattat
    11341 tccggattca ccggatggct ggacacagag ggacataccg atatctacgt caatctgcgc
    11401 tgcatggaaa taaagccggg tgaagccatc ctgtatgcag gaggaggaat actggcttcc
    11461 tcggaagtag aatcggaatg ggtggaaacg ggagacaaga tgaatacgat gcggagcatc
    11521 cttcatcctg actttataag taaacaaatg gaaacaatta aagtagaaga ataatgtatt
    11581 cagacaaaaa gaacatactt cagttggtgg cacttctcaa agcgcacggt gtgcggaaaa
    11641 tagtgctttg tcccggcagc cgtaatgctg ccatcgtaca cactctggcc aatatagagg
    11701 acttcacttg ttattctgta accgatgaac gcagtgccgg tttttttgct atcggcctat
    11761 ctttacaagg gggaggtcct gccgcagtat gctgcacctc cggttcggcc ctgctgaacc
    11821 tgcaccctgc cgtagccgaa gctttttacc aacaagtacc tctgattgtc atttctgccg
    11881 accgccccgc cgcctggata ggacaaatgg acggacaaac cctgccccag ccccatgtgt
    11941 tcggaacgtt agtcaagatg tctgtcaacc tgcccgaagt acatacagag gaagacgaat
    12001 ggttttgcaa ccgcctcatc aacgaagcca tactggaaac cacccaccac ggcaaaggac
    12061 ccgtacatat caatgtaccc atttccgaac ccatctaccg cttcaccgcc aaaacacttc
    12121 ccgaggcacg tgtcatcacc cgttatcagg gactgagcgt gtacgaccgt gactataagg
    12181 aactgatcga acggctgaac aagtacaaca agcgcatggt cgtggtaggc cagatgaatc
    12241 tgatttacct gttcgagaaa aaatatgtga aaccgcttta taaacatttc gcctggttga
    12301 cggaacatct gggcaaccag accatccccg gcattcctat caagaatttc gacgccgccg
    12361 tttattccat gacgccggag cgccaggaag acatggcccc cgaaatactg attacctacg
    12421 gcggacatat cgtatccaag caattgaaga aatacctgcg caatcatccc ccgcgcgaac
    12481 attggcatgt tgccgccgac gggaagatag ccgatttata cggttgcctg accaccgtca
    12541 tcgagatgga tccgtttgag ttcttggaaa aaatagcttt cctgctggac aacaaaccga
    12601 cccattatcc gctgatgtgg gaaaactatt gcaaaaccat tccgatgccg gatcttgctt
    12661 attccgaaat ctccgttatc ggaaaactca ttcaggcatt acccgaaccc tgtgccctgc
    12721 atctggcaaa cagctccacc gtgcgctatg cacagttatt tacagttcct ccccgggtgg
    12781 aaatctgttg caaccggggc gtgaacggca tagaaggctc cctgtccacc gccatcggtt
    12841 atgccgccgc ttccagcaag ctgaatttca tcatcatagg cgacttgagc ttcttctatg
    12901 atatgaacgc actgtggaat caaaattacg gtgccaacat ccgcatcctg ttactgaata
    12961 acgaaggagg agaaatattc cataccctgc ctggaatgga caaatcaagc cgttcccggg
    13021 agtttatcac agccgagcat tacaccaccg ccaaaggctg ggcggaagaa cgtggcttta
    13081 tttacatgaa agtgaccgga gaagaagagc tggaagaagc gatgcagcca ttcacctcac
    13141 ccgagacaag gatgcaaccc atgctgctgg aggtgtttac cgacaaggaa aaagacacca
    13201 ccctattaag agaatattat cacggactta aaaataaaaa tgaataatgg aaacaagaaa
    13261 atggaaaacc atcaaagaat atcaagatat tctgtttgac ttttacaacg gaatagcgaa
    13321 aatcaccatc aaccgtccgc gttaccgcaa cgcgttcacc cccaccacta cttcggaaat
    13381 cagcgacgcc ctgtattact gccgcgagtg ccaggatatc aatgtagtgg ttctgaccgg
    13441 agcaggcgac aaagccttct gcagcggggg agatatgcac gtaaaaggtc atggcggtta
    13501 tatcggcaca gatggagttc cccgtctgaa tgtgctggac gtacaaaagc aaatccggtc
    13561 actgccaaaa ccggtcatcg ccatggtaaa cggttacgcc atcggcggcg gccatgtgct
    13621 gcatgtggta tgcgatctga ccattgcctc agaaaatgcc attttcggac agacaggtcc
    13681 caaggtaggc agcttcgacg ccggattcgg ctcttcctat ctggcacgca tcgtagggca
    13741 gaagaaagcc cgtgaaatat ggttcctttg ccgtcaatac tccgcacagg aagcactgga
    13801 aatgggatta gtcaatacag tcgttccttt cgaccgcctg gaagacgaaa ccgtggcatg
    13861 ggcagaaaag atgatggagc acagcccgct cgctcttcgt atgatcaaag ccggactgaa
    13921 tgccgaactg gacggacaag ccggcataca agaacttgcc ggagatgcca ccatgctgta
    13981 ttacatgaca gaggaagcgc aggaaggagg gaaggcattt ttggaaaaac gcaagccacg
    14041 gttccaggat tatccgaagt tcccataaac aaactacaaa ttcaaagcat ggacattgaa
    14101 gaattcagaa aatattgtct ttcgttaggt gacgtttccg aaaagatgcc atttggcaaa
    14161 tttgctgcaa gatatgattc catccttgcc ttttatgttt atggacacat gttctgtttt
    14221 atagacattg acaatttcac ttttgtcaat gtcaaatcta cttcggacga aattgagtat
    14281 ataaaagaga gacatgtttc agtcggcaat cccatcaacc aaagtctgaa acattggctt
    14341 caacttaatt ttgatggtga tattcccgac acgagcatat acacatgggt ccaacgcgcc
    14401 tttgagattg tcagggataa atataccaaa ccaactacac ataaaaaaaa atgttccaaa
    14461 cccaaattat aaaaaaacaa ttacacttca agcaacctgc cggtacttcc agaggagtat
    14521 atactacccg ggatgtatgg tacatcctcc tcaccgacat cggcagctgc cactatggcg
    14581 tgggtgaatg cgcccctctc cctgccctga gctgtgatga tatcccctca tacgacgagg
    14641 tgttggccac tgcctgcaag aacctggaaa agaacgggga aatagaccgg gaagccttgc
    14701 ttccctatcc gtccatcctg ttcggtatgg aaaccgccct gctgcatttc cgggcacgca
    14761 gcctgcaatt ctggcacacc ccgttcagca aaggcaaaga gggtatcccc atcaacggac
    14821 tcatctggat gggaaacttt gacgagatgt accggcgcat cggggaaaag atgtaaatcc
    14881 ggaaaaacca gacgtgccgc ttaacaaaaa cgatgcgttt caaaaa
//
