LOCUS       c00045_gnlPro..        24323 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JDOKLLGJ_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:46:40
            Original ID  :: gnl|Prokka|JDOKLLGJ_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 47102
            Orig. end    :: 71425
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24323
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[57102:71423]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..24321
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24323
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24323
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             132..758
                     /locus_tag="ctg45_38"
                     /transl_table=11
                     /translation="MEQQTTFIPDGMNAFERNVKRIGDCIIAGILLIIFSPLFLICYIA
                     VKREDGGPAIFKQERIGRFGRPFYIYKFRSMRLDAEKMGPALYRGGKDKRLTKVGKFLR
                     EHHLDELPQLWNVFCGQMAFIGPRPERKYFIDQIMEHDARYVFLYQIRPGVTSYATLYN
                     GYTDTMDKMLRRLRYDLFYLQHRSWWFDFKILVKTFINICFGKKF"
     CDS             894..1187
                     /locus_tag="ctg45_39"
                     /transl_table=11
                     /translation="MLSTIEYLSLLRKYMRENAVKYGISRMGIFGSVARGEQHDGSDVD
                     ICVEIDRPSIFTLVHIKEELEKLFKCPVDVVRLRNNMDELLRNCINKDGIYV"
     CDS             complement(1276..1689)
                     /locus_tag="ctg45_40"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHIRHRGFRDIGYHFYIT
                     RDGEIHPGRPLEKVGAHCRNHNAHSIGICYEGGLDADGRTKDTRTLEQRGSLLALIREL
                     RKRFPKALIVGHHDLNPMKECPCFRCVEEYKEL"
     CDS             complement(1694..1798)
                     /locus_tag="ctg45_41"
                     /transl_table=11
                     /translation="MSNSSSRSVWIFIIKVIITVATAVGGLIGVQSCM"
     CDS             complement(1888..2388)
                     /locus_tag="ctg45_42"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLSKLAEHMSKHNSP
                     YSSGVIKGVLTDMVDCIKELLLDGKSVKIDDLAIFGVGIRSKAAETLEEFSLEKNITGM
                     RLKARATGNLSTTNLKLDSQLKQQAEYQKPTTPGGGGSGSGNTPDPKPNPDEGDEEAPD
                     PTV"
     CDS             2608..2826
                     /locus_tag="ctg45_43"
                     /transl_table=11
                     /translation="MIEFKIRAYGRMELAQLYSPELTGIAAYRKMNKWIVRCPGLQERL
                     SDLGYQPQHRSYTPLEVRAIVDALGEP"
     CDS             complement(3046..4884)
                     /locus_tag="ctg45_44"
                     /transl_table=11
                     /translation="MTDIESLRLLTEAVETAGADIAPTYAEYVQLAFAIATDCGEAGRE
                     FFHRLCRISAKYQSAHAERMFSNALTKQQGAIHLGTAFHLAESTGVKICREDRKEVMNN
                     RTGTVGTESSPHNFSTHAHVYNKVEEEKSESEELLEGSDPHHPLPTFTLEDWPKLLLRI
                     ISYGTTATQKDVLLLGALTALGATMERYVRCHYAGKYQSPCMQSFIVAPAASGKGVLSL
                     IRLLVMPIHDDIRQQVEKEMNVYKKAKVAYEMMGKERAKAEIPEIPLNRMFLISGNNTG
                     TGILQNIMDNNGTGLICETEADTISTAIGSEYGHWSETLRRAFDHDWLAYNRRTNQEYR
                     ENKKSYLSLLLSGTPAQVKPLIPSVENGLFSRQLFYYMHGIYQWINQFDENETDLEAIF
                     TSIGLEWKKLLNLLKEHGLHTLRLTDEQKQEFNDLFSELFTRSTIANGREMNSSIARMA
                     VNICRIMSVVAMLRAFENPQPYQYQASSHPLLTPDKEIATDNIKDGIITRWDMTITPED
                     FKAVLNLVKPLYQHATHILSFLPPSEVSHRANADRDAFFEALGIQFTRAQLLEQATTMG
                     IKPNTALTWLKRLVKQGLIVNLDGKGTYAHARVCVC"
     CDS             complement(4951..5577)
                     /locus_tag="ctg45_45"
                     /transl_table=11
                     /translation="MQNFFRMSYFMPPIAPIRNEQGQTVTPATLTPFCEVSVEQVYQMI
                     TCNENLKALTEQVRSAEDIRMAKTSLLPYVTPCGTFIRRNSKFFASPSGLVVVDIDNLD
                     SYQKAVEMRRTLFDDPFLHPVLAFISPSNRGVKTFVPYSNLYTDDQSRNVRESMSWAME
                     YVEMTYGSEMNNSIETVQKAVDTSGKDIVRACFLSHDPQALFREY"
     CDS             5731..5880
                     /locus_tag="ctg45_46"
                     /transl_table=11
                     /translation="MENKIVHPKLGEFIEKVLKVAHVNLSKMCQEIHMGPATYQKVKKG
                     KKKL"
     CDS             6045..7607
                     /locus_tag="ctg45_47"
                     /transl_table=11
                     /translation="MEDLQRLYPIGIQTFSKIREGNFLYVDKTEYVYRMTHSASSYMFL
                     SRPRRFGKSLLTSTLHSYFSGREELFRGLAMEKLEKEWIQYPVLHFDMSMAKHVDKDKL
                     MNLLDFMLTEHERTLGIDAAGTDPNLRLTNLIKRAYEQTGRKVVVLIDEYDAPLLDVVH
                     ERENLGVLRDVMRNFYSPLKACDPYLRYVFLTGITKFSQLSIFSELNNIKNISMDEPYA
                     AICGITENEILTQMKEDVDRMAVKLNITAEEVLAKLKENYDGYHFTYPSPDIYNPFSLL
                     NAFADGKFNSYWFGSGTPTYLIKMLDKFGVEPSEIGNKLAAVEEFDAPTETMSSITPLL
                     YQSGYVTIKDYDKELELYTLDIPNKEVRVGLMRSLLPYYVTNDTREATNMVAFISRDIR
                     KGDMDAALRRLQTFLSTIPQCDHTKYEGHYQQVFYIIFSLLGYYVDVEVRTSRGRVDVV
                     LRTEATLYVMELKLDKNATVAMEQINLKNYPERFALCGLPVVKVAVNFDSESGTLGDWM
                     IEK"
     CDS             7883..8143
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_gamma"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_48"
                     /sec_met_domain="OAD_gamma (E-value: 8e-14, bitscore: 44.1,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIETAILLMVVGMATVFVILLIVIYLGKLLITLVNKYAPEEVI
                     PAKKEALQGPAPIPGNIMAAITAAVNVVTLGKGKITKVEKL"
     CDS             8172..10001
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 59.8; E-value:
                     5.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_49"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.5e-19, bitscore:
                     59.8, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="HMGL-like (E-value: 6.7e-21, bitscore:
                     66.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 4.5e-25, bitscore:
                     80.5, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKREVKFSLVFRDMWQSAGKYVPRVDQLVKVAPAIIEMGCFARVE
                     TNGGGFEQVNLLFGENPNRAVREWTKPFHEAGIQTHMLDRALNGLRMSPVPADVRKLFY
                     KVKKAQGTDITRTFCGLNDVRNIAPSITYAKEAGMISQCSLCITHSPIHTVEYYTNMAL
                     ELIKLGADEICIKDMAGIGRPVSLGKIVANIKAAHPEIPIQYHSHAGPGFNMASILEVC
                     EAGCDYIDVGMEPLSWGTGHADLLSVQAMLKDAGYQVPEINMEAYMKVRALIQEFMDDF
                     LGLYISPKNRLMNSLLIGPGLPGGMMGSLMADLESNLESINKYKAKHNLPFMTQDQLLI
                     KLFNEVAYVWPRVGYPPLVTPFSQYVKNLAMMNVMAMEKGKERWGMIADDIWDMLLGKA
                     GRLPGTLAPEIIEKAEREGRKFFEGNPQDNYPDSLDKYRKLMKENKWEVGEDDEELFEY
                     AMHPAQYEAYKSGKAKEDFLADVAKRRAEKDKSPEEDAKPKTLTVQVDGQAYRVTVAYG
                     DAELLAAPVAAAPAGEGKDVLSPLEGKFFLVKNAQESALKVGDAVKEGDVLCYVEAMKT
                     YNAIRAEFSGTITAICANPGDTVSEDDVLMKIG"
     CDS             10001..11236
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_50"
                     /sec_met_domain="OAD_beta (E-value: 9.9e-143, bitscore:
                     467.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEIFENLYDMTAFSNIIAEPQFLIMYAIAFVLLYLGIKKQYEPL
                     LLVPIAFGVLLANFPGGDMGVIQADENGMVMINGVMKNIWEMPLHDIAHELGIMNFIYY
                     MLIKTGFLPPIIFMGVGALTDFGPMLRNLHLSIFGAAAQLGIFTVLLVAILMGFTPQEA
                     ASLGIIGGADGPTAIFTTIKLAPHLLGPIAIAAYSYMALVPVIIPLVVKLFCTKKELSI
                     NMKEQEKKYPSKTEIKNLRVLKIIFPIVVTTIVALFVPSAVPLIGMLMFGNLVKEIGSN
                     TFRLFDAASNSIMNAATIFLGLSVGATMTAEAFLNWTTIGIVIGGFLAFALSITGGIFF
                     VKLVNLFSKKKINPLIGATGLSAVPMASRVANEIALKYDPKNHVLQYCMASNISGVIGS
                     AVAAGVLISFLA"
     CDS             complement(11352..12632)
                     /locus_tag="ctg45_51"
                     /transl_table=11
                     /translation="MKEMKTQLILFSLLLLGSTAWAQQPCLSQDAYREKVEAYSQILKQ
                     QKLKTLASSEARKIAHTGFLPKIDVNADGTLNMSDLSAWNEPVGEYRNHTYQGVFVVSQ
                     PLYTGGALNAQHQIAKADEKLNQLNEELTLDQIHYQSDAVYWNASASKAMLQAADKYQS
                     IVKQQYDIIQDRFDDGMISRTDLLMISTRLKEAELQYIKARQNYTLALQQLNILMGEAP
                     NTPVDSLYNIGMISAPVRILPLEDVLQRRADYASTEVNIMKSQAQRKAALSQFNPQLNM
                     YFSGGWATATPNLGYDVSFNPIVGVNLNIPIFRWGARFKTNRQQKAYIGIQKLQQSYMT
                     DNINEELSAALTKLTETESQVKTAKENMSLANENLDLATFSYNEGKASMVDVLSAQLSW
                     TQAHTNLINAYLAEKMAVAEYKKVTSE"
     CDS             complement(12675..15713)
                     /locus_tag="ctg45_52"
                     /transl_table=11
                     /translation="MNLAKYSLDNTKIIYFFLAVLLIGGITSFGKLGKKEDAPFVIKSA
                     VIMTRYPGAEPAEVERLITEPISREIQSMSGVYKIKSESMYGLSKITFELQPSLSASSI
                     PQKWDELRRKVLNIQPQLPSGASTPTVSDDFGDVFGIYYGLTADDGFTYEEMRNWAERI
                     KTQVVTADGVMKVALFGVQTEVVNIFVSTNKLVGMGIDPKQLANLLQSQNQIINTGEIR
                     AGVQQLRVTANGMYANIDDIRNQVITTKAGQVKLGDIAVIEKGYLDPPSNIMHVNGKRA
                     IGIGVSTDPQRDVVQTGENVKVKLNELLPLMPVGLELQSLYLENEIANEANNGFIINLI
                     ESILIVIVIIMLVMGLRAGLLIGSSLIFSIGGTLLIMSFFGVGLNRTSLAGFIIAMGML
                     VDNAIVVTDNAQIAIARGVNRRKALIDGATGPQWGLLGATFIAICSFLPLYLAPSAVAE
                     IVKPLFVVLAISLGLSWVLALTQTTVFGNFILKAKTGDSTKDPYDKPFYHKFAFVLGVL
                     IRKKAVTLVSMVILFIISLIIMGTMPQNFFPSLDKPYFRADVFYPDGYSINDVVKEMKS
                     VEEHLAKQPEVKKVSITFGSTPLRYYLASTSVGPKPNFANVLVELTDSKYTKEYEEDFD
                     GYMKANYPSAITRTSLFKLSPAVDAAIEIGFIGPNVDTLVSLTNQAIAIMHQNPDLINI
                     RNSWGNKIPVWKPVYSPERAQPLGVSRQGMAQSIQIGTTGMTLGEYRQGDQVLPILLKN
                     NQLDSFRINDLRTLPVFGTGNETTSLEQVVSEFDFQYRFSNVKDYNRQMVMMAQCDPRR
                     GTNAISAFNQVWSQVQQEIKIPEGYTMKYFGEQESQVESNEALAKNLPLTFFLMFVTLL
                     FLFKTYRKPTVILLMLPLIFIGIVLGLLVLGKSFDFFSILGLLGLIGMNIKNAIVLVDQ
                     IDLETAAGKKPLDAVISATTSRIIPVAMASGTTILGMLPLLFDAMFGGMAATIMGGLLV
                     ASALTLFVLPVAYCAIHRIKGEQ"
     CDS             complement(15710..16762)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_53"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 6.9e-12,
                     bitscore: 37.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIYVIALAAILFQGCGQKKEMTAPATRPVKTTIVESRSVIRKD
                     FSGIVEAVEYVKLAFRVSGQIISLPVIEGEKVKKGQLIAAIDPRDIALQYAATKSAYET
                     ASAQVERNKRLLSRQAISVQEYEISLSNYQKAKSEYELSSNNMRDTKLTAPFDGSIEKR
                     LVENYQRVNSGEGIVQLVNTQNLRIKFTIPDAYLYLLRAKDPRFLVEFDTFKGHVFKAR
                     LEEYLDISTEGTGIPVSITIDDPSFDRDLYAVKPGFTCSIRFTADVGPLVQDSWTIIPL
                     SAVFGESDGNNMYVWVVEDNKVHKRKIVVNAPTGEAQVLVSEGLKPGEQIVIAGVYQLV
                     EGESIKSIDK"
     CDS             complement(17408..17662)
                     /locus_tag="ctg45_54"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             18085..19089
                     /locus_tag="ctg45_55"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE"
     CDS             complement(19169..20503)
                     /locus_tag="ctg45_56"
                     /transl_table=11
                     /translation="MKRIILLAFLCTTTLVMAQRINHVQEAIANYDYEAALTLIAKEKP
                     TIPLLLQKGKAQRGLGMNTEALSTYQEIITNDTANTRAYIEAAECCRSLAKYQQALKYY
                     EQALDLNPENKYVRIQYIGLLLSLQKFQDALGESSLMTEKDSSAIALHLQAQSFEGMGE
                     LLPATGCYYNIQEKYPDDYLAAAKLAALNIAGSYFNEAIEATEKYRQIDTTNIAVNRQN
                     ALAYCLNKDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAEEKYYEAHDFLEAARKHDP
                     ENVNLLYYLGRACAKTSWKKLGVEYLEKALDLTIPKDSNMVRLYIGMTDCYKMAQMPKE
                     QIESIRERYRKYDKQNHKLLYDMAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKL
                     NERGELVLGTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             complement(20678..21838)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_57"
                     /sec_met_domain="OAD_beta (E-value: 6.4e-153, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(21840..22274)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_58"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.9e-21, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKTA
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(22299..23219)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_59"
                     /sec_met_domain="OAD_gamma (E-value: 1.7e-14, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(23251..24321)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_60"
                     /sec_met_domain="CT_Btheta (E-value: 8.3e-207, bitscore:
                     679.4, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QISGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTG
                     EDVSQENLGGASVHSTKSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPI
                     DRLEDSLNDIIPDSPNKPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGI
                     VANQPKFLAGVLDSNASRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGA
                     KLLYAYGEATVPKVTITLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVL
                     YAREAKDQENPAQFLAEKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQ
                     TKKLSNPAKKHGNIPL"
ORIGIN
        1 aacttcctct gaatatctct ataatgtctt tatacgggtg attactagga tgatgcccaa
       61 cactttacga gctatcttgt ataaaaaagc tctgagaaaa tagtctttaa ccaaactata
      121 attaataatt tatggaacaa caaacaactt ttattcccga cggaatgaat gcttttgagc
      181 gcaatgtaaa gcgaattggg gattgcatta ttgcgggcat attactgatt attttttctc
      241 ctttattttt aatctgttat atagctgtga aacgtgaaga tggtggtccg gctattttca
      301 aacaggaacg tatcggtcgt ttcggccgtc cgttttatat ttataagttc cgcagtatgc
      361 gtttggatgc ggaaaaaatg ggtcctgcgc tatatagggg tgggaaagat aaacgattga
      421 ctaaagtggg taagtttttg cgtgaacatc atttggatga attgccgcaa ctttggaatg
      481 tcttctgcgg gcagatggct tttattggtc cacgtccgga gcgtaagtat ttcattgatc
      541 aaataatgga acacgatgct cgttacgtat ttttgtatca gatacgaccg ggtgttactt
      601 cgtatgctac gttatacaat gggtacacgg atacgatgga taaaatgttg cgtcgtcttc
      661 gctatgattt gttttatttg cagcatcgct catggtggtt tgattttaag atcttggtga
      721 agacatttat aaatatttgt tttggcaaga agttttagca gagaaaattg ttgtatttat
      781 agtgaaacac cgttgttgaa tacgaagaag ttggtaatgg gcagaaaaaa gcaatatctc
      841 tttgattatt gaaggaaaat ttctttcttt gtaatagact aaaagtatct attatgttaa
      901 gtactataga atatctatcc cttcttcgta aatacatgcg ggagaatgct gttaaatatg
      961 gtatatctcg tatgggaata tttggctcag tagctcgtgg tgagcaacat gacggtagtg
     1021 atgttgatat atgcgtggag atagataggc cttctatatt tactttagtt catattaagg
     1081 aagaattgga aaaactgttt aaatgtcctg tagatgtagt tagattgcgg aataacatgg
     1141 atgaattgtt gagaaactgt ataaataaag acgggatcta tgtgtagaaa acaaatcaaa
     1201 aatgatttgc cccaattgaa agaaatactg gaacaaatca ttgatgagtt tgataagtgt
     1261 gattgacctc ctcttttaca actccttata ttcctctaca caccgaaaac acggacattc
     1321 tttcatcgga ttcaaatcat gatgccctac tatcaacgct tttggaaacc tctttcgtaa
     1381 ctcacgaatt aaggctaaca acgatccccg ttgctctagc gtacgtgtat ccttagtccg
     1441 tccgtcagca tccagtcctc cttcgtaaca gattcctata gaatgtgcgt tatgattccg
     1501 gcaatgtgct ccgacctttt ctaacggtcg tcccggatgt atttccccat cacgtgtgat
     1561 gtagaaatgg taaccgatgt cacggaatcc ccgatgtcgg atatgatcct gtcggcaagc
     1621 ctccgccgag agggattttc cctctggcgt ggcactgcaa tgaatgataa tcagtgtgat
     1681 ggtccgcata agtttacata cagctttgta ctcctatcaa accacctaca gcagtagcga
     1741 cagtgatgat tactttgata atgaaaatcc atacggatcg tgatgatgaa ttactcatag
     1801 gttttgattt taaatgaaaa aaatattgat ttttaatgag tctttagccg tgataagcta
     1861 aagactttgc ggggttcagg ttatgactta aacagtcggg tccggtgctt cttcgtctcc
     1921 ttcgtccgga ttaggttttg gatcgggagt gttgcctgaa ccggaacctc ctcctccggg
     1981 cgttgtcggt ttctgatact ccgcctgctg cttcaattgg ctgtcgagct tcagattggt
     2041 cgttgataag tttccagtgg cacgtgcttt gagccgcata cctgtgatgt tcttctccag
     2101 cgagaactct tccagcgttt cggcagcctt gctgcggatt cctacaccga agatggctag
     2161 atcatcaatt ttcacacttt tgccgtcgag cagcagttcc ttgatgcagt ccaccatatc
     2221 agtaagcacg cctttgatca ccccactaga atacggtgaa ttgtgctttg acatatgttc
     2281 ggcaagtttg gaaagatcga aagtctcgtc gcttaccgcc cgggcgaacc acttgcccgc
     2341 attcaagcct ttcttttgct ggttctgata gattttgtaa cgaatcataa aataataatt
     2401 ttaaagagtt aaacatactt tcgtgaggat ttctcccttt cgatgacaca aagatagcat
     2461 actgtaactc ggaaaaatcg gttgtgtaca gtgacagtcg gtaatgtgca attgttgtca
     2521 gttatagtct gttattccct ggtaaaacgt aggtaatgtg aatatatttt gttacttttg
     2581 tgactgtaaa acagaaactt atttgtcatg atagaattca aaatacgtgc ttacggtcgt
     2641 atggaactgg cacagcttta ttctcccgaa cttacgggca ttgccgctta ccgcaaaatg
     2701 aataaatgga ttgtccgctg tcccggtctt caggaacgcc tgtccgattt aggctatcag
     2761 ccgcagcacc gttcttacac tccgttggag gtaagggcaa tcgtggatgc gttgggcgaa
     2821 ccatgagcag gtaataagta ttaggtaaca ggtaataagt gttgtagact gcgaggggcg
     2881 ttttgtatta gctaaagcta agctttagag gccataaagc accgctttag aagtcgtaaa
     2941 gcatagcttt agccaataca aaacgctata ctctgatttt cataaagaaa cgataaaaga
     3001 cgatgttatc aacaggtaca gtaggtacac ttttccggcc cttccctaac acacgcacac
     3061 gcgtgcgtgc gcgtaagtac ctttaccgtc aagattgaca atcagtccct gttttaccag
     3121 tcgtttcagc caggtgaggg cagtgttggg cttgattccc atagtcgtag cctgctccaa
     3181 caactgtgca cgggtaaatt ggatacccag tgcctcaaag aatgcgtcac ggtcggcatt
     3241 ggccctatgg ctgacttctg aaggaggaag gaaagacaag atatgcgtgg catgctgata
     3301 gagtggtttc acaaggttca acacagcctt aaaatcttcg ggagtgatcg tcatatccca
     3361 acgggtaatg ataccgtctt tgatattatc agtggcgatt tccttgtccg gtgtaagcag
     3421 gggatgagaa gatgcctggt attgatacgg ctgaggattt tcaaaagcac gaagcatggc
     3481 cactactgac atgatacggc agatgttgac agccattcgg gcgatggaac tgttcatttc
     3541 tctgccattg gcaatcgttg accgggtgaa cagttcggaa aagagatcat tgaactcctg
     3601 tttctgttca tctgtgagcc ggagtgtgtg gagaccatgt tccttgagta agttcaagag
     3661 ctttttccat tccagaccaa tggaggtgaa gatggcttcc aagtccgttt cgttctcgtc
     3721 aaactgattg atccattgat agatgccgtg catataatag aacagctggc gtgaaaaaag
     3781 tccgttctct actgaaggaa tgagtggttt cacctgtgcg ggtgtccccg aaagcaggag
     3841 agagaggtaa cttttcttgt tttcccggta ctcctgattg gtacgtcggt tgtatgctaa
     3901 ccagtcatgg tcgaatgctc tgcgaagcgt ctcactccag tgaccgtatt ccgaaccgat
     3961 ggcggtagag atcgtatccg cctcggtttc gcagatgagg cctgttccgt tgttatccat
     4021 aatattttga aggataccgg taccggtatt gttgccggag atgaggaaca ttctgtttaa
     4081 aggtatttcg gggatttccg ctttggcacg ctctttgccc atcatttcgt aggcgacttt
     4141 tgcctttttg tagacattca tctctttttc aacttgttgg cggatatcat cgtggatagg
     4201 cataacgagc aggcggatga gtgatagtac tcccttgccc gaggctgccg gagctacaat
     4261 gaaggattgc atgcagggcg attggtattt gccggcataa tgacatctca cgtatcgttc
     4321 catggtggca cccagggcag tcaatgctcc gagcaagagt acgtcttttt gagtggcggt
     4381 agtgccataa cttatgatac gtagcagtag cttcggccag tcttctaagg tgaaagtagg
     4441 taatgggtga tgcgggtcgc tgccttccag cagttcttct gattcactct tttcttcttc
     4501 tactttatta tatacgtgcg cgtgtgtgga aaaattgtgc ggtgaacttt ctgtacctac
     4561 tgtacccgtc cggttgttca taacttcctt ccggtcttcc ctgcagattt ttactcctgt
     4621 cgattcagcg aggtgaaatg ccgttccgag atgtattgct ccctgctgtt tcgtgagtgc
     4681 attggaaaac attcgttcgg catgggcgga ttgatacttg gcggaaatcc ggcacaggcg
     4741 atgaaaaaac tcccgtcctg cttcaccaca gtccgttgcg atggcgaatg ctaattgtac
     4801 gtactcggcg taagtgggtg caatgtcggc acctgctgtt tcgactgctt cggtgaggag
     4861 gcgtaaagat tcaatatcgg tcattttttg ataattgaca attgacaaat gataattgac
     4921 aattgaagtt tgatcattcg tgattataat ttaatattct ctgaatagtg cttgtgggtc
     4981 atggctgagg aagcaggctc ttacgatgtc tttgccggag gtgtctacgg ctttttgaac
     5041 tgtttcgatg gagttgttca tttctgatcc gtaggtcatt tctacgtatt ccattgccca
     5101 gctcatactc tctcttacat tacggctctg atcgtctgtg tacaggttgc tgtaaggtac
     5161 gaatgttttc acaccccggt tgctgggact gataaatgcg agtacagggt ggagaaaagg
     5221 atcgtcgaac agtgtacgac gcatttctac ggctttctga taggagtcga ggttatctat
     5281 atctaccact acgagtccgg aaggagatgc gaagaattta ctgttccggc ggatgaatgt
     5341 gccgcacgga gtcacgtatg gcagcaagga tgttttcgcc attcgtatat cttcggcgct
     5401 gcgcacctgt tcggtcagtg ctttgagatt ttcattgcag gtgatcatct gatatacttg
     5461 ctctactgag acttcgcaga agggagtgag agtggcgggt gtaacggttt gtccttgttc
     5521 gttcctgatg ggagcaatcg ggggcatgaa ataagacatt ctgaaaaagt tttgcataga
     5581 atacttctat taggacgttt aataaatgac tttgactttc aaagcatggt gcgaaagtaa
     5641 gacaaataaa ataagtcgag ttcagatatg tctgaagtag tgtgaaaatg tttaatatat
     5701 aagacgtgtt tttaactaat aataagaaaa atggaaaata aaatcgtgca tcctaaactc
     5761 ggtgagttta ttgaaaaggt gcttaaagta gcacatgtga atctttcaaa aatgtgtcaa
     5821 gagatacata tgggacctgc tacttaccaa aaggtaaaaa aggggaagaa aaagctctga
     5881 ttcattatga gcgtattctt gaatattatt ataggactcg caccgaagaa gagtttttgg
     5941 agaaagtgaa tgagtgggca aaactttata ttcgatataa gaaggagaag aatgacattt
     6001 gaatattgga attttttagt agctttgtga aaaagaaagt tgttatggaa gatttgcaga
     6061 gattatatcc tatagggata cagacatttt ctaagattcg tgagggaaat ttcctctatg
     6121 tagataagac agaatacgtt taccggatga cgcattctgc ttccagttat atgttcctga
     6181 gccgtccgcg tcgttttggt aaatcattgt taacctctac gttgcatagc tatttctccg
     6241 gtcgtgaaga actgtttcgt ggattggcga tggagaagct ggagaaagaa tggatacagt
     6301 atccggttct gcacttcgat atgagtatgg ccaagcacgt ggacaaagat aaactgatga
     6361 atcttttaga cttcatgcta acagaacacg aacgtacact agggattgat gcagcaggta
     6421 cagaccctaa tttgcgcctg actaatctga taaaacgtgc ttatgaacag actggcagga
     6481 aggtcgtggt ccttattgat gaatatgacg ctcctttgct ggatgtggta cacgaacggg
     6541 agaacttggg ggtattgcgt gacgttatgc gtaacttcta tagtccgttg aaagcctgtg
     6601 atccttattt gcgctatgtg tttcttacag gtatcactaa attctcacag ctcagcattt
     6661 tcagtgaact caataacatc aaaaatatca gcatggatga accttatgct gccatttgtg
     6721 gcataacgga gaatgagata cttacccaaa tgaaagaaga tgtggatagg atggctgtca
     6781 aattgaatat tactgcggag gaagtactgg ctaagttgaa agagaattat gacggctatc
     6841 atttcactta tccatcgccc gacatctata atccattcag tctgctcaat gcttttgcag
     6901 atgggaaatt taattcttat tggtttggta gcggcactcc tacctatctg ataaagatgc
     6961 tggataagtt tggagtagag ccttctgaaa taggaaataa attggcggcg gtcgaagaat
     7021 ttgatgctcc cactgaaacg atgagtagca ttactccatt gctgtatcaa agcggctatg
     7081 tcactatcaa ggattacgat aaggaattgg aactatatac gttggatatt cctaataaag
     7141 aggtgagggt gggattgatg cgaagcttgt tgccttatta tgtaaccaat gacacacgtg
     7201 aggcgacgaa catggtggct tttatttccc gtgatatccg gaaaggtgat atggacgcgg
     7261 cattacggcg tttgcaaacc tttctgtcta ctatacctca atgcgatcat acaaagtacg
     7321 aaggtcatta ccagcaggta ttctatatca tattcagctt gctgggatac tatgtggatg
     7381 tcgaagtacg tacttcccgt ggtcgtgtgg atgtagtgtt gcgtactgag gccacattat
     7441 atgtgatgga attgaaactg gataagaatg cgacagttgc tatggaacag ataaatttaa
     7501 agaattatcc ggaacgcttt gctctatgtg gactgccagt ggtgaaggtg gctgttaatt
     7561 ttgatagtga aagtggcaca ctgggggatt ggatgattga aaaatagaga ttgataagta
     7621 aatataaaaa gtgtaaggac gaaggccatt ttctttaatt atcagattaa taacatttta
     7681 ataactccct aaaataaaaa gagccccgca aggggctttt cctttgtctt tttaatagac
     7741 atgcaaagaa taatgtgttt tttcttattg taaccttacg atttatactt ttttattcct
     7801 ctcttaatta attttatcac aaatatttgg tattttcgga cgctttttgg acaaacgact
     7861 tgaattacta atagtttatt atatggaaaa tatcgaaaca gcgatcctgc tgatggtggt
     7921 cggcatggct accgtatttg ttattctgct gattgtgatt tatttaggta agttactgat
     7981 tactcttgtc aacaagtatg ctcccgaaga agtgattcct gcgaagaagg aagcgctaca
     8041 aggtcctgcg cctattccgg gtaatataat ggcggctatc acagcagctg tgaatgtggt
     8101 gacattagga aaaggaaaga ttacaaaagt agaaaagtta taaacctatc aaaagtatat
     8161 catagaaaaa catgaaaaga gaagttaagt ttagtctggt tttccgagat atgtggcaat
     8221 ctgccggaaa atatgtacct cgtgtagacc aactcgtaaa ggtagctcct gccatcattg
     8281 aaatgggctg tttcgcccgt gtagaaacaa atggcggagg ttttgaacaa gtgaatttat
     8341 tgtttggtga aaacccgaat agagccgtgc gcgaatggac gaagccgttc cacgaagccg
     8401 gcatacagac acacatgctc gaccgtgcat tgaacggact ccgtatgagc cccgttccgg
     8461 cagacgtccg caagttgttc tacaaagtaa agaaagcaca aggcacagat atcacccgta
     8521 cattctgcgg attgaacgac gtacgcaata tcgctccttc catcacgtat gccaaagagg
     8581 caggcatgat ctcacagtgt tcactctgta tcacccattc gccgatccac acggtagagt
     8641 actacaccaa tatggcgtta gaacttatca agctgggggc ggacgagatt tgcatcaaag
     8701 acatggcagg tatcggtcgc cccgtttcat tgggcaagat cgtggccaat atcaaagcgg
     8761 cacatcctga aattcctatt cagtatcata gtcatgccgg tcccggtttc aacatggcaa
     8821 gcatcctcga agtatgcgaa gccggttgcg actacattga cgtaggtatg gaaccgcttt
     8881 catggggtac gggacacgcc gatcttctca gcgtacaggc tatgctgaaa gatgccggat
     8941 atcaggtacc ggaaatcaat atggaagcct acatgaaagt gcgtgcgctg attcaggaat
     9001 ttatggatga cttcctcggc ttgtatatca gcccgaagaa ccgtctgatg aactcgctgc
     9061 tgatcggtcc gggacttcct ggcggtatga tgggtagtct gatggctgac ctcgaatcga
     9121 atctggaatc tatcaacaag tataaagcca aacataacct gccgtttatg acacaggatc
     9181 agctgctgat caagctattc aacgaagtgg cgtatgtatg gccccgcgtc ggttatcctc
     9241 cattggtaac tccgttcagc cagtacgtga agaaccttgc catgatgaat gtgatggcaa
     9301 tggagaaagg caaggaacgc tggggaatga ttgccgacga tatctgggat atgctgctag
     9361 gtaaagcagg acgcctgccg ggtacactgg ctcccgaaat catcgagaaa gccgaacgtg
     9421 aaggacgtaa attcttcgaa ggtaatccgc aggacaatta ccccgactca ctcgacaagt
     9481 atcgcaagct gatgaaggaa aacaaatggg aagtgggaga ggacgacgaa gaactcttcg
     9541 aatatgccat gcatccggct cagtatgagg cttacaagag tggaaaagcg aaggaagact
     9601 tcctggcaga cgtggcaaaa cgtcgtgcag agaaagataa atcgccggaa gaagatgcaa
     9661 aaccaaaaac actgactgta caggtggacg gacaggctta tcgtgtgacg gtagcatacg
     9721 gagatgccga actgcttgct gcacctgtag ctgcagctcc ggcaggagag ggcaaagatg
     9781 ttctttctcc gctggaaggt aaattcttcc tggtgaagaa tgcgcaggaa tctgccttga
     9841 aagttggcga tgcggtgaaa gagggcgatg tgctttgtta tgtggaagca atgaagactt
     9901 acaacgctat ccgtgccgaa tttagcggta cgataactgc tatctgcgct aatccgggag
     9961 acactgtttc agaagatgat gtattaatga agataggata atgaacgaga tatttgagaa
    10021 cttatatgac atgactgcgt tcagcaatat cattgccgaa ccgcagtttc tgataatgta
    10081 tgccatcgcg ttcgtcctgc tttatctggg tatcaagaaa cagtacgaac cgttgctgct
    10141 tgttccgatt gctttcggtg tgttgcttgc caacttcccc ggaggagata tgggagtgat
    10201 acaggcagac gagaatggta tggtgatgat aaacggtgtg atgaagaata tctgggaaat
    10261 gcctttgcat gacattgcgc atgaactggg aattatgaac ttcatctatt atatgctgat
    10321 caagaccggt ttcctgcctc cgatcatctt tatgggggtc ggtgcgttga cggacttcgg
    10381 accgatgttg cgtaatctgc atctttccat ctttggagct gctgcacagt taggtatctt
    10441 tactgttctg ttggtagcca tcctgatggg attcactccg caagaagctg cttcactggg
    10501 tattatcggt ggtgcggacg gaccgacagc catctttaca acgatcaagc tggctccgca
    10561 tttgctgggt ccgatcgcta ttgccgctta ttcttatatg gcactggtgc ctgtgatcat
    10621 tccgttggta gtgaagctgt tctgtactaa gaaagaactg agcatcaaca tgaaggaaca
    10681 ggaaaagaaa tatccttcga agacggaaat caagaatctg cgtgtactga agattatttt
    10741 cccgattgta gtgactacga ttgtagctct cttcgtccca agtgcagtac ctttgatcgg
    10801 tatgctgatg ttcggtaatc tggtgaaaga aatcggaagc aatactttcc gtctgttcga
    10861 cgctgcttcc aacagtatca tgaatgctgc tactatcttc ctcggacttt cggtaggtgc
    10921 aaccatgacg gctgaagcct tcttgaactg gacgacaatc ggtattgtca tcggtggttt
    10981 ccttgcattt gctctttcta ttaccggtgg tatcttcttt gtgaagttag tgaatctatt
    11041 ctccaagaag aagattaatc cgctgatcgg agcgaccgga ctgagcgctg ttccgatggc
    11101 aagccgtgtg gcgaatgaga ttgcgttgaa atacgatccg aagaatcatg tattgcagta
    11161 ttgtatggca agtaacatct caggggtaat cggctcggca gtagctgcgg gtgtactgat
    11221 ctccttcctt gcataataaa aagaacaacc aataaaaatt aggcacggat tacgcggata
    11281 aacacggttt ttagttactc aactcttaaa accgtgaaat ccgtgtcatc cgtgcctaat
    11341 tttgttttta tctattcgct ggtcaccttc ttgtattcag ccacagccat cttctctgcc
    11401 agataagcat tgatcagatt ggtgtgtgct tgcgtccatg acaactgggc ggaaagtaca
    11461 tctaccatgc tcgcttttcc ttcattgtag gagaaagtgg ccagatccag attctcattt
    11521 gccagactca tgttttcttt cgctgttttc acctgagatt ctgtttccgt cagtttggtg
    11581 agagctgccg acagttcttc gttgatattg tccgtcatat aactctgttg caacttttgt
    11641 attccgatat atgccttctg ctgtcggttc gtcttgaaac gggctcccca gcggaaaatg
    11701 ggaatattca gattgactcc tacgatggga ttaaaagata cgtcgtatcc caagttgggt
    11761 gtggccgttg cccagccacc gctgaaatac atgtttaatt ggggattgaa ctggctgaga
    11821 gccgctttac gttgtgcctg gctcttcatg atgtttactt ccgtactggc ataatcggca
    11881 cgtcgttgca aaacatcttc cagaggcagt atccggacag gagcggagat cattccgatg
    11941 ttgtacaggc tgtctacagg agtattcggt gcttctccca tcagaatatt cagctgttgc
    12001 agcgctaatg tataattctg gcgggctttg atatactgca gttccgcttc tttcagccgg
    12061 gtggaaatca tcagaagatc tgtacggctg atcattccgt catcgaaacg gtcctgaata
    12121 atgtcatatt gctgtttgac aatgctctgg tatttgtcgg ctgcttgtag catggctttt
    12181 gaagcggagg cattccagta gacagcatca ctttgatagt gaatctggtc taacgtgagt
    12241 tcctcgttca gctggttcag cttttcgtct gccttcgcta tctgatgttg ggcattgagc
    12301 gcaccgcctg tgtagagtgg ctgtgatacg acaaatactc cctggtaggt atggttgcgg
    12361 tattcgccca ccggttcgtt ccatgcgcta aggtcgctca tgttcagggt accgtctgca
    12421 tttacgtcga ttttcggcag gaaacctgta tgggctatct ttcgcgcctc cgaactggcc
    12481 aatgtcttta gtttttgttg tttcaatatc tggctgtaag cctccacttt ttcgcggtag
    12541 gcgtcctgac tcaggcaggg ctgttgcgcc caggctgtgg agccaaggag caacagtgaa
    12601 aatagtatga gttgggtttt catttctttc atggataatc ttttaatgga taatggatag
    12661 ttgataatgg ataattattg ttctcctttg atccggtgga tggcgcaata ggctacagga
    12721 aggacgaata gtgtcaatgc cgaggctact aacagtccgc ccatgatggt ggcggccatt
    12781 ccgccgaaca tggcgtcgaa cagtagcggt aacataccca gaatcgttgt tccggaggcc
    12841 atcgctaccg gaatgatgcg actggtcgtg gcactgatga ctgcgtccag cggttttttg
    12901 cctgctgctg tttccaaatc gatttggtct accagtacga tagcgttctt gatgttcata
    12961 ccaatcagac ctagcagacc caatatggag aagaagtcga acgacttgcc gagtacgagc
    13021 agtcccagca cgataccgat gaagatcagc ggcagcatta acaggatgac ggtcggcttg
    13081 cgatacgtct tgaacaagaa gagcagcgtc acaaacatca ggaagaatgt cagcggtaag
    13141 tttttggcca gcgcttcatt cgattccacc tgactttcct gttcgccgaa atacttcatg
    13201 gtatatcctt ccggtatttt tatctcttgc tgtacttgcg accatacctg gttgaaagcg
    13261 gaaatcgcat tggttccgcg acgcgggtcg cattgtgcca tcatcaccat ctgccggtta
    13321 tagtctttca cgttcgagaa ccggtactgg aagtcaaatt cagatactac ctgttccagg
    13381 ctggtcgtct cgttgcctgt cccgaatacg ggcagtgtgc gcagatcatt gatccggaat
    13441 gaatccagct ggttattttt caataggata ggaagtacct gatctccctg ccggtattct
    13501 cccaaagtca ttcctgtggt accgatctga atgctctgtg ccattccctg tcgggataca
    13561 cccagcggtt gtgcccgttc cgggctgtaa accggtttcc agacgggtat cttgtttccc
    13621 cacgaattgc ggatattaat taaatccgga ttctggtgca taatggctat tgcctgattg
    13681 gtaagtgata caagcgtatc cacattcgga ccgataaagc cgatttcgat agccgcatcc
    13741 actgcggggg acagtttgaa caagctggtc cgtgtgattg cactcggata attggctttc
    13801 atatatccgt caaaatcttc ttcgtattct ttcgtatatt tactgtctgt cagttcgacg
    13861 agtacattgg caaaattcgg tttcggacct acggaagtgg aggcaaggta ataccttagc
    13921 ggggtgctgc cgaatgtgat ggataccttt tttacttctg gctgcttcgc caggtgctct
    13981 tctaccgatt tcatctcttt cactacgtca ttgatgctgt atccgtccgg atagaataca
    14041 tccgcccgga aataaggctt atcgagcgac gggaagaagt tctgcggcat cgttcccata
    14101 ataatgagcg agatgatgaa gaggatcacc atggatacca gtgtcactgc tttcttgcgg
    14161 atcaatactc cgagaacgaa agcgaactta tgatagaacg gcttgtcgta tggatctttc
    14221 gtgctgtcgc ctgttttggc tttcagaatg aaatttccga atacggtagt ctgcgtcagg
    14281 gcaagtaccc agctcagtcc tagtgaaatg gcaagtacca caaacagcgg ttttacgatt
    14341 tccgctacag cagagggagc aaggtaaagc ggcaggaagg agcagatggc aatgaaagtt
    14401 gctccgagca agccccattg tggtccggtt gctccgtcta tcagggcttt ccgtcggttt
    14461 acacctcggg caatggctat ttgggcgttg tccgtcacta cgatggcgtt gtccaccagc
    14521 atacccatgg cgatgataaa tcctgccaag gacgttctgt tgagtccgac gccgaagaaa
    14581 gacatgatga gcagtgtacc tccgatagag aaaatcagcg aagagccgat gagcagaccg
    14641 gcacggagtc ccatcaccag catgataatg acaatcacga tcaggatgga ttcgatcagg
    14701 ttgatgataa atccgttgtt ggcttcgttg gcgatctcgt tttcgaggta gaggctttgc
    14761 agttccagtc ccacaggcat gagggggagg agctcgttca gttttacttt tacgttctca
    14821 cccgtctgca ctacatctct ttgcgggtcg gtggaaacac cgatgccgat agcccgtttc
    14881 ccgttcacat gcatgatgtt ggatggaggg tcgagataac ctttctcgat cacggctatg
    14941 tcgcccagtt tcacctgtcc ggctttggtg gtgattacct ggttgcggat atcgtctatg
    15001 ttggcataca ttccgttggc tgtcacccgt aactgctgta cgcctgcacg gatttctccg
    15061 gtgttgataa tctggttctg cgattgcagc aggttggcca gctgtttggg atcgatcccc
    15121 attcccacca gtttgttggt agaaacgaag atgttgacta cttccgtctg tacgccgaac
    15181 agcgctactt tcatcacgcc gtctgctgtg acaacctgcg tcttgatccg ttccgcccag
    15241 ttgcgcattt cctcataggt gaagccgtca tctgccgtca gtccataata aatgccgaat
    15301 acgtcgccga aatcatcgga gacggtcggg gtggaagcac cgctgggcag ctgcggctga
    15361 atattgagca ctttgcgtcg cagctcgtcc catttctgag ggatggaact ggcggaaagt
    15421 gagggttgca gttcgaacgt gattttggag agcccgtaca tggactctga ttttatcttg
    15481 tacacgccgc tcatactttg tatctcacgg gagataggct ctgtgatcag ccgttctact
    15541 tctgccggtt cggctcccgg atagcgtgtc atgatgaccg ctgatttgat aacgaagggg
    15601 gcatcttctt tcttgcccag ctttccgaag gaggtaatac ctccaatcag cagtacggca
    15661 aggaagaaat agatgatctt cgtgttatcc agtgaatatt ttgctaaatt catttgtcta
    15721 ttgatttaat actttctcct tctaccaact ggtatactcc tgctatgacg atttgttctc
    15781 cgggtttcag tccttcggac acgagtactt gcgcctctcc tgtgggggca ttgacgacga
    15841 ttttgcgttt gtgcactttg ttgtcctcta ctacccagac atacatgttg tttccgtcac
    15901 tttcgccgaa aacagcactg agcgggatga ttgtccagct atcctgcacc aatgggccta
    15961 catcggctgt gaaacggatg ctgcaagtga agccgggctt cacggcatat aagtcccggt
    16021 cgaatgaagg gtcgtcgata gtgatgctga ccggaatacc cgttccttcg gtggatatgt
    16081 ccagatattc ctccagtctt gccttgaata catggccctt gaaggtatca aactctacaa
    16141 ggaaacgggg atctttggca cggaggagat aaagatatgc atccggtatg gtgaacttga
    16201 tacgcaggtt ctgtgtgttg accagttgta cgatcccttc tcctgaattg acacgctggt
    16261 agttctccac cagccgcttc tcgatagaac cgtcgaaagg ggccgtcagt ttggtgtcac
    16321 gcatgttgtt gctggacagt tcgtactccg attttgcttt ctgataattg gaaaggctga
    16381 tttcatactc ctgcacggag atcgcttgcc gggagagcag gcgcttgttg cgttccactt
    16441 gtgcggaagc cgtttcgtag gcagacttgg tggcagcata ctgcaatgcg atatctctgg
    16501 gatcgatagc tgcaatcagt tgcccttttt tcactttctc tccttcgata acaggcaggc
    16561 tgatgatctg tccgctgacg cggaatgcca gtttgacata ctccactgct tctacaatgc
    16621 cggagaagtc ttttctgatt actgaccttg attcgacaat agttgtctta acaggtcggg
    16681 tggcgggtgc cgtcatctct tttttttgcc cgcagccttg aaataggatg gctgcgagtg
    16741 caatcacata gatatttttc ataagtcgtt cattgtttgg gaagtaaaca atttgatact
    16801 tgactatgtt cagtagagac gggtatatta gaaatgtgaa attagtatca acattaaagg
    16861 aaaatgattg tttatagata aaaaatgcct tttctgttga ttttatcaga gattattccc
    16921 acttttgcac cgcactagta ttacagtcgc ggaatgcgat atgagaattt aattctcgaa
    16981 tttaagctac gagcatgtgg gaatatgctc gtggcttcct tagatatacg gttctgtccc
    17041 ccgtgtggag cgttaatgcg cccactgtat ctcatccctc gtggactgta atatgtagtg
    17101 caacgggtca gcaggaccgt cttttttgcc tgctgaatat tattatatat aataggaagt
    17161 atttctcctg aatagtacta tttaataaac catcattttt caggagatca gacaatataa
    17221 tggtatggta tattccctta actataccat ttttatatta cctggtaata gttcccctta
    17281 gccagttaat atacggaccg cactactctg tgaagaatgg tgcggtcctt tagtttatct
    17341 atgaaacgaa aaagaggaaa tttccaaccg gaaatctcct cttttttcat cttaacgaaa
    17401 gattgaatta tttcttctta cggtcaccgt aacggctcat gaacttatca acgcgacctg
    17461 cagtatctac caatgtagat ttacctgtat agaacgggtg agaagtgttt gagatttcaa
    17521 tcttcagcaa cggataagtt tcaccttcga attcgatggt ttctttagtt gctacagttg
    17581 atctagacaa aaacatgtca ccatttgaca tatctttaaa tactaccgga cggtatgatt
    17641 ctggatgaag gccttttttc atttcagtat ctgttttttt aatttatatt ctgttactat
    17701 tttggtaaga aatagtgtaa tggtcatttt cagagcgcaa agataatgct tttctgtgaa
    17761 atagaaaaag gttttctaaa atttctgatt tctaatttat gatttctgat ttgctatgca
    17821 gattttggtg attaaatgaa tgaaaaatga ggtataaata aggagatata aatccgaagg
    17881 cataaatcag aattcagaaa tcataaatcc caaagtttgc aaggtggaca ttacaatcta
    17941 atgtcacact cgtattcctg ctaaattttg ctgtctgatt taaacctttt tctactatat
    18001 ttttctttcc gatgttcgtt attcgatgga taatgcttac ttttgcgtag aatttttatt
    18061 cactaacaat aaactttaaa caaaatggta aattacaaag atttaggatt ggtaaacaca
    18121 agagaaatgt ttgctaaggc tatcaaaggt ggatatgcta tcccagcatt caacttcaac
    18181 aatatggaac aaatgcaggc tatcatcaag gctgctgttg aaactaaatc tcctgtgatt
    18241 cttcaggttt ctaaaggtgc tcgtcagtat gctaacgcta ctttgttgcg ttacatggct
    18301 cagggtgctg tagagtacgc aaaagaatta ggttgcgcac atcctgaaat cgttcttcac
    18361 cttgaccacg gagatacttt tgaaacttgc aaatcttgca tcgattcagg tttctcttca
    18421 gttatgatcg acggttctca tcttccttac gaagaaaatg ttgctttgac taagaaggtg
    18481 gttgaatacg ctcatcagtt cgacgtaaca gttgaaggtg aacttggtgt attggcaggt
    18541 gtagaagatg aagtttcttc tgaccaccac acatacactg accctgaaga agtaatcgat
    18601 ttcgctactc gtacaggttg tgactcattg gctatctcta tcggtacttc tcacggtgct
    18661 tataagttta ctccggaaca gtgccacatc gatccggcta ccggtcgtat ggttcctcct
    18721 ccattggctt tcgaagtatt ggatgctgta atggaaaaac ttccgggatt ccctatcgta
    18781 cttcacggat catcttcagt tcctgaagaa gaagttgaaa caatcaacaa gtttggtggt
    18841 gctctgaaag ctgctatcgg tattcctgaa gaagaattgc gtaaagctgc caagtctgct
    18901 gtttgcaaaa tcaacatcga ctcagactct cgtctggcta tgactgctgc tatccgtaag
    18961 actttcgctg aaaaaccagc tgaattcgac ccacgtaagt atcttggtcc ggctcgtgac
    19021 aacatggaaa aactgtacaa gcacaaaatc cttaacgtgc tgggttcaga caacaaattg
    19081 gctgaataat cacagattat cctattatat agaaaggctg caatcgtttg acggttgcag
    19141 ccttttttac gtaatatcct ttatctgctt attccggttt ctgagcgggc acatttcctc
    19201 ccaagaagaa atcttctatc ttttgcttac tttgaatgtc tttcagccag ttggctgcag
    19261 cattataata attcttagtg cctaaaacga gttcgcctcg ttcgtttagt ttcgcttctt
    19321 cttccttatc ttctttcggg cgtgttttta agaatgcttc cagacagcgt tcggtatttt
    19381 tcttgtcttt cagcgaatag aaataaatga aagccatatc atagagcagt ttatgatttt
    19441 gtttatcgta tttccggtag cgttctctga tcgattcaat ctgctcttta ggcatctgtg
    19501 ccattttgta gcagtcggtc atgccaatat agagccgtac catattactg tctttgggaa
    19561 tagtcagatc aagcgctttt tcgagatact ctacgcctaa cttcttccat gaagtcttgg
    19621 cgcaggcacg gccgagataa taaagcaggt ttacgttttc aggatcatgt tttcgggcgg
    19681 cttccagaaa gtcatgtgct tcgtaatatt tctcttccgc ataatagctg atacccagat
    19741 aataacaggt atgaaaagaa ctgtcgccct ggctcaccag gtattcataa cgctggatag
    19801 cggtaggata atccttattc agacaatatg ccagtgcatt ctgacggttg acagcgatat
    19861 tggtggtatc aatctgccga tatttctccg tggcttcaat tgcttcgttg aaataagaac
    19921 cggctatgtt cagtgcggcg agcttggcgg cggcaagata gtcgtcgggg tatttctctt
    19981 gtatattata gtagcacccc gtggcgggga gaagctctcc cataccttcg aaactttggg
    20041 cctgcagatg caaggcgatg gcggaactgt ctttctctgt catcagacta ctttctccta
    20101 aagcatcctg aaacttctgt aaagagagca gtagtccgat gtattgaata cgcacatatt
    20161 tgttttccgg attcagatca agtgcctgtt cataatattt cagtgcctgt tggtatttgg
    20221 ccaatgaacg gcagcattcg gctgcttcga tatatgcacg ggtattggca gtgtcattgg
    20281 ttatgatttc ctgataagtg gaaagtgctt ctgtattcat cccaagtccc cgttgtgctt
    20341 tacctttttg caagagtagg ggaattgtcg gcttttcttt ggcaatgaga gtgagagctg
    20401 cctcgtaatc gtagtttgct attgcttcct gaacatgatt gatgcgctgc gccatcacca
    20461 gggtggtggt acaaaggaag gcgaggagaa taatccgttt cataaatatt tattttagtg
    20521 tgtcgtaaca aagacgcaag atgctaaaaa atatcgtatt tacgaattat tcgtagcctt
    20581 tttggaatag attaacggaa tgataagaga agataacata atgataagtg cggatattgc
    20641 atctaaaaca gcaatatccg cacctaatat tttgtcccta cattaagaat cctaacagga
    20701 taccggcagc aacagccgaa ccgattacac ctgctacgtt cggacccata gcgtgcatca
    20761 gcaagtagtt ggtaggatca tattccagac cgacaacttg tgagatacgt gcagagtcgg
    20821 gaacggcaga tacacctgca ttaccgatca acggattgat cttattgccc ttcttgagga
    20881 agaggttgaa gatcttaacg aagatcacac ctgatgcggt agcaatgata aatgacagag
    20941 caccgagggc gaagatcttg atggagtcga gtgtcaggaa ctcagaagcc tgagtagaag
    21001 cacctacggt caaacctaac aggatagtga ttgtgtcaat cagcggaccg ctggctgtgt
    21061 tagccagacg acgggttaca ccactttctt tcaacaggtt accgaagaac agcataccca
    21121 acagaggcag accggaagga accaggaagc aggtcagcaa cagaccgata atcgggaaaa
    21181 tcactttctc tgtatgagaa acggcacgtg gcggtttcat acggataacg cgttcgtgtt
    21241 tggtggtgag cagacgcatg ataggcggct gtatcaccgg aactaacgcc atataggagt
    21301 aggcggatac cgcaatggct cccattaagt taggtgccag cttggacgaa aggaagatag
    21361 ccgtcggacc atctgctcca ccgatgatac cgatagcacc ggcctgcatc gggtcaaatc
    21421 ccatttccaa tgcgatcatg tatgcaccga agataccaaa ctgggcagcc gcaccgatca
    21481 gcatcagctt cggattggag attagcgccg agaagtctgt catggcaccg atacctaaga
    21541 agatgagcgg tggataccag ccggacgtta ctccctgata caatatgttc aatacagaac
    21601 cttcttcata tataccgact tttagtccgg cgtccatatt gaaaggtata ttaccgatca
    21661 gaataccgaa tccgatagga attaacaaca tcggctcgaa ctctttggct acagctaagt
    21721 aaataaagcc taaaccgata atgatcatag caatatgtcc acctgtcgcg ttggcaaatc
    21781 ccgtgtaggt ccagaaatcg gcaaggttat ttcctaaaaa gttaataaaa tctcccatat
    21841 tattcaataa ttacgaggtc attaccttca agaacagaat ctcccttgtt gacattgatg
    21901 gcagtcactt taccgtcttt gtctgcattg atattgtttt ccatcttcat ggcttccaat
    21961 ataatgatag tctgtcctct tttcactgta tcacctacat ttactttgat gtcaaggata
    22021 acgcctggca gtggggactt aacgcctgat ttgccggtag aaggagcagc cggttttact
    22081 accggtgtgg taggagcagc cggtgagtta ggcatagggc gtactactgc cggtttggga
    22141 gcagttttcg gttgtttctc catttctact ttgtaatgcg taccgttcac ttctacatga
    22201 gcgatattat cttcaatatc tccgatggtt actttgtatg agttaccgtt gattttatat
    22261 ttatattctt tcatcgtttt atctttttag ggaatgattt actttctgtt aggattttca
    22321 cgcaaggtgt aaatcttcga actccacggt gaataactgc gcttcacacg agtgatggtc
    22381 agcaccgttt cttctacgtc gtgtacctca tcctgcattt cgtgtaatgc cattgaaata
    22441 gcagcataaa cttcacccgg agcctgtgaa agctctttcg cttcgacttt atcgatgcct
    22501 ttagccttca tcgcattgcg tttgctcagg ttgacagcaa ctttacctac caccttgaag
    22561 gcaatgaaga gaagaatcaa tccgcagaat actacgctca tggctgaaat agacataccg
    22621 ataccgactg agtcatgttc ttcgaacttt tccatcttgg cattactgtc aagggttttg
    22681 ttgttcgtgc tcggggttac gtatttgtct ttgcttccgc cttttacttc ccagtctgct
    22741 gctccgtcgc ttatgcgtgc ataagactgg ttgggaccta aagttcctgc tggtatgaca
    22801 acttgatcaa gtagctttct gcctgaatca aaaagaccga cccaattggc tgtttcggga
    22861 ttcagtttga agctggtatg gaaggttcca cgattaggtt cgccatctgc ccaaaataac
    22921 gcatgttggc gtggctttac taatgtaagt atgtcacctt tcgggataaa ataggttact
    22981 gtatcgcccg gctggctgct tactttcaat aaacaagctg ctaagtctgc gctaccgtat
    23041 gatttgttga atatttcaat ccatgcactg tgcaagccgt agtcatcctg aaagttgttt
    23101 tgattgtcta tcaggacttc attcagcaat agcttattgt tcgacttttg ctctccgcag
    23161 gaagtcaatc caatcagcaa cagcagagaa aggaatattc cgattttggt tttgttcata
    23221 atcgttcttg ttttaatgtg aaaagttgga ttacaacgga atattaccat gtttcttcgc
    23281 cggattagac agtttcttag tctgcaactg ctgcaaagca cggatcacgc ggaaacgtgt
    23341 gttacggggt tcgatgacat catcgatgta accatactta gctgcattat aagggttggc
    23401 aaacagtttt gtatattctg cttctttttc ggcaaggaac tgagccggat tttcctggtc
    23461 tttggcttca cgcgcgtaca atacttctac tgcacctgca ccacccatta cagcgatttc
    23521 agctgttggc caagcatagt tcatgtcacc acgaagttgt ttacaactca tcacgatgtg
    23581 agaaccaccg taagatttac gcaatgtgat tgttacttta ggtacagtag cttcaccgta
    23641 agcatacagc agtttggcac catgaaggat aacgccattg tattcctggc ctgttcccgg
    23701 aaggaatccc ggtacgtcta ccaacgacac gatagggata ttgaaagcat cgcagaaacg
    23761 aacgaaacgt gcgcctttgc gagatgcgtt gctgtcgagt acaccggcaa ggaatttagg
    23821 ctgattggct acaataccta cagactgacc gttgaaacgg gcaaaaccga taatgatatt
    23881 cttggcatag tctttctgga tttccaggaa ttcgccgttg tctacgatag cgctgataac
    23941 ctcgtacata tcatacggtt tgttggggct gtcggggata atatcgttca gtgaatcttc
    24001 cagacggtcg atcggatctg tgcaatccac gtatggagct tcttcgaggt tgttttgagg
    24061 aatatagctc agaagtgtgc ggatcaatgc cagaccttct tcttctgttt tggcagtgaa
    24121 atgagtaaca cccgatttgg tagagtgaac gcttgctccg ccgaggtttt cctggcttac
    24181 gtcttcaccg gttacagttt tcacaacttt cggacctgta aggaacatat aagaagtacc
    24241 ttccatcatc agtgtgaagt ctgtcagtgc cggagaataa acagcaccgc cggcacaagg
    24301 accgaagata ccggaaatct gcg
//
