LOCUS       c00028_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LOKPKIEH_28.
ACCESSION   c00028_gnlPro..
VERSION     c00028_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:23:46
            Original ID  :: gnl|Prokka|LOKPKIEH_28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 214599
            Orig. end    :: 239238
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[224599:229238]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             238..1752
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.7; E-value:
                     2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_175"
                     /sec_met_domain="AMP-binding (E-value: 9e-82, bitscore:
                     268.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1767..2009
                     /locus_tag="ctg28_176"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2013..3395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_177"
                     /sec_met_domain="MBOAT (E-value: 2.1e-21, bitscore: 70.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3414..4454
                     /locus_tag="ctg28_178"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4559..4951
                     /locus_tag="ctg28_179"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5144..5776)
                     /locus_tag="ctg28_180"
                     /transl_table=11
                     /translation="MMLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGV
                     DYVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKAL
                     GKPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVD
                     HYQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5757..6278)
                     /locus_tag="ctg28_181"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6299..7090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_182"
                     /sec_met_domain="F420_oxidored (E-value: 3.8e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7087..7419)
                     /locus_tag="ctg28_183"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7422..7919)
                     /locus_tag="ctg28_184"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8125..8667)
                     /locus_tag="ctg28_185"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8785..9768
                     /locus_tag="ctg28_186"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRIFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_187"
                     /sec_met_domain="Glyoxalase_4 (E-value: 5.1e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_188"
                     /sec_met_domain="CT_Btheta (E-value: 4.8e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_189"
                     /sec_met_domain="OAD_gamma (E-value: 3e-15, bitscore: 50.6,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_190"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.9e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_191"
                     /sec_met_domain="OAD_beta (E-value: 9.4e-153, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14787..16118
                     /locus_tag="ctg28_192"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16133..17425
                     /locus_tag="ctg28_193"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIEDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             18051..19901
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_194"
                     /sec_met_domain="Alpha-amylase (E-value: 1.3e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPCWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSIVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             20059..20499
                     /locus_tag="ctg28_195"
                     /transl_table=11
                     /translation="MTNNESARELVLQTLRTRMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20512..21579
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_196"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 5.2e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLAHLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21584..23179
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_197"
                     /sec_met_domain="MFS_1 (E-value: 3e-13, bitscore: 43.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIALLFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIVLFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23274..24278)
                     /locus_tag="ctg28_198"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gtatcaataa agtatcgtgt tgtctatccc attcaaagtc gtcggctatg aagccaacgc
       61 tatttcccct tccgaaagag ggaaagcgag accgggcacg tgcgtaccac ataattaaca
      121 ttctttaatc gattgtgcgt agggagatca gaccatttca ctgtcatctt aataaacgat
      181 ctcaagaaga tatataaaga acccctaaac ccaaaacatg aataaaaact aatggatatg
      241 acaacatctt cccagaagga tattatcaat gatattcttt ccgccatgca atgttatccc
      301 gaaaacgaag cattcattat tgacgataaa cattatactt atgcccaact cggtgaaata
      361 acagcttcta tcacccattc gctatcagaa ataaaagatg aaaaaatcgg aatcgtagcg
      421 gaaaaccgga ttgaaaccta tgctgctatt ctggcagtac tagccggcgg aaagacctat
      481 gttatcctgc atcctgccta cccggaagag cgtaatctca aaatagccgc tctggccgga
      541 ctgcgtactt tgctctgtac aagtgacact gaccggtcag cattcggcac cggacacttc
      601 agaatcatcg atacggaccg gctaccggga aaaacactgt cagaacagca gtcccattca
      661 tcggacgaag aaaggaacgc ttatatcatt tttacatcgg gaagcacagg cgagcccaaa
      721 ggagtgccca tcacacgggc taacttgaac gccttttacc gggcatacag ttcgctcgac
      781 tggaatctgg atgaacatga tcgcatgttg caaatgttcg aacttacatt cgatgtatcc
      841 gtagtatctt tactgtatcc tcttacttta ggtgctgccg tttatacggt aggccatcag
      901 gatgtaaagc acttcaaggt gtttgaactt ctggagaagt atcaactgac ctttgccact
      961 gtcactccct cactgctaca actcctttca ccctacttcg acgaaatcaa tctgccctct
     1021 ctgaaatatc tgggagtatc ggcagaagca tcgcaaaccg agctgttgga gcgattcaga
     1081 aaatcggcac ccaacgcaac gttcatcaac ctatacggac cgaccgaagc tacgatttac
     1141 tgcacctgtt accgtattcc ggcttcggac aaatgcaagc attacaacgg aatggtggct
     1201 atcggaaaac catttcccgg catccgcgcc atcattgccg acgaagaagg aaacgagcta
     1261 cctcaaggag agacgggaga actttgggta tccggccggc aggtaatgaa aggttatctg
     1321 gacgacccgg aaaaatcggc attggttctg atacaccgtc ccgacggaca aatctattac
     1381 cggaccggag acttgtgtat tctggatggc gacggggata ttatttattg cggacgtaaa
     1441 gactatcagg tgaaaataca gggtttcagg atagaactga gtgaaataga atatactgcc
     1501 cagtcgtttt tcaagactcc ctgcagcgtg gctgccgttc cgttgctctg cgacggaatc
     1561 tgtaacgaat tacatctggc cgtcgagaca actgaatgta cccaaagcgc attgatagaa
     1621 tatctgaaag aaaagctgcc caaatacatg ctgccgaagc agattcattg tatttcccaa
     1681 tttccggtga ccaatagtaa taaaacagac cgtaaaaaga ttgccgaact gataaaagag
     1741 aagaaactct aaaaacaata ataaatatga atcgagaaga agtattaaaa caactacaaa
     1801 gcattttccg tgatatctta aaaaaggaca acgtatgtat cgacgaatca tctacctcaa
     1861 aagatgtaga tggctgggac tcgctaaccc acatgcaaat tatagctcaa atcgagaaac
     1921 atttcggagt acgtttcaat ttcagggagg tcattaagtt caagaatgtc ggcgatttgt
     1981 gcagtgcctt attaaccaaa atggaataaa cgatgcagtt cctctctttt agtttcctgg
     2041 ccctgtttac cctctgtttc ttcctctact atgcagtcaa aggccgtgcc cgcaacctca
     2101 tactactggt aaccagttgt attttcatcg gatggtacta tctgcctttc ctgttgacgg
     2161 cagtagtggt agcactgttc accttctttt gggcacaatg gatggaaagc agggcaaaag
     2221 ccggaaaaaa gaccaaaccc gtctatatcg caggaatcat cgccctgatc ggcggatggc
     2281 tccttcttca tggcacggtc atagatgata tcatctttcc acttgggatg tcattttaca
     2341 catttcaagc catcagttat ctgacagacg tgtactggca agagcaacgc agcgaaagaa
     2401 actgggtgga tttcctgatc tatatgcttt tcttcatgaa gtttctctcc ggccctatcg
     2461 aacggggtgg agacctgttg ccacaattga aagatccccg cccgttcatc tactcaaacg
     2521 cggtgaccgg actgaaatat attttactcg gactgatcaa gaaactgctg atagccaatc
     2581 agatctcccc acaaacagat gtcatgtttc attcgatcca tgacctctcg ggtgtacaac
     2641 tgctaatgac ttgcctactc taccctatcg aactgtatgc cgatttttcg ggttatacgg
     2701 atattgctat cggaggggcc tatatgttcg gcatcaagtt gtcgcccaac ttcaaccgcc
     2761 cgtttgcagc acgctcgact gccgacttct ggcgccgttg gcacatgtca ctctccttct
     2821 gggtacgcga ttatctctat gtaccgctaa ccgccggtac ccgtaactgg ggacagtggg
     2881 gaatctactt cagcctcctc atcacctttc tcgcattggg tttgtggcat ggggccggat
     2941 tgactttcgc catatacggc ctgattcagg gtgtccttat ctgctgggaa atgaaaacag
     3001 ctgctttccg caataatctg ccccaatata taggaaaata tgcggccgac agcttgctga
     3061 ttgtccggac ttatctattg ttcgcactct cgcttatatt ctttcgtgta caatcgctga
     3121 gcgatgcctg gtatttctta cggaacatct cgttcgaggt acattcttcc tggaaagaaa
     3181 tgaacatcgg catacgcgat cataattgca tcgtagcagg ttcggcccta ttactggtgt
     3241 tgatctacga atattatgca tctaagtaca acctgatgga aacacttgaa cgccaacccg
     3301 catggttacg gtggagtgtc tactatctgt tggtattcgc tctgctgatg ttaggcaaat
     3361 ttgacacgga aactttcatc tatttacaat tttaaccgaa accctttacg cgcatgctac
     3421 atcattcatc gagaatctcc cccaagacac gtttttgcct gaagttgctt ttactgatcc
     3481 tgccgctgat cccgatagtg gttgtctatt ttatgtttga tccttatagg gtattacacc
     3541 cctacaaacg attcgacgac tctcccatgc tactcaacga agcccatgtg ggatggcaga
     3601 attatctgca gaatcgcgat tcgatagcct ataactcctt tatactcggc aactcctgta
     3661 ccatggcatt cctgacagga gaatgggaaa aatacctgga taagaacgac catgccgtac
     3721 gcttctatga caacggagaa agcctgggtg gcgtccgtca aaagcttcag ctgctcgact
     3781 ctgtaggtgc acccctgaaa aatatactga tcgttctgga taaaaaatca ctggacaaaa
     3841 acgctccttt atcgggcaac aatcatctgt tttcggccga agcagccggc atcagccaat
     3901 tgggattcca gttgagattc ctgcaggagt tcctttatcc ggacagaatg attccttaca
     3961 tagattatct gatccgacat aagtatgctc cttatatgaa aggggttata aatccgggag
     4021 atcccgtcag ggagccttac acgaacaatt ttatcaatcc cagagaaaaa gagatcgcgc
     4081 aagatggcga aatatactgg agccgtcatg aaaaagaatt caagaagcga acgaatgcgg
     4141 gtatggaaga acttcctgtt atatttgcca gccagattca ggtacttcgc tccatcaaaa
     4201 aaatctgcga taagcaccac acgaacctga agttcatcat cggtccggat tactatcaga
     4261 aaaagaccag ccgggaagac ataaaaatat tgaaggctat actgggtgat tccgctgtct
     4321 gggatttcac gggaatcaac gaatacacag ccgacataca tcattattac gaacccggtc
     4381 attatcgtcc gctgctggga gcacgcttac tgaaagccat ttatcaggat caagacacct
     4441 gccacaggca ataaaagttc ctcccataac agtagcacac acagaagaag agcatcctcg
     4501 atccgaaaaa aataattaga ccaaagaaaa caattatatc acattaaaaa cttagattat
     4561 gaaaaagatt ttattattgc tatccgtctg tatttcattt tcatcatgct gtacattatt
     4621 cagcagttcc aaacaagata tcacctttac gggaatgaat ggaactaaaa tctacgaagc
     4681 atcgaccaaa cagaaaatag cggaaatcaa agaagacaat agtgtcactg tacaaatcaa
     4741 aaagaaaagg gaagacaaac aactagtagc caaaaaggaa gggtaccaaa cgactccctt
     4801 tgtcctggaa tctacattta acaatgcctg cctgtggaac attctatttt ggccgggctt
     4861 tctggtagat ttgggtacgc aaaagatgaa caaatgggat aacacaatta tcaatatcga
     4921 aatggagaaa gaaaatacag aaaacaaatg atcaaactat aatttcgcat ggcactcttc
     4981 tccttccacg gagggagtcg ccatacggaa tcatgcgacc tacaaggaag gcataattca
     5041 ccacaaggca acacagagtt ttttataaaa gttctttaga gaataaatct actctgtgag
     5101 actctgtgct actccgttgt atatacgagt ttcggcacac tctctatagt tgtttcaatt
     5161 ctctgtataa tttctgaatg ggaagtccca ttacattgaa gtagctgccg gatatggatt
     5221 ctactccgac aaaaccgatc cactcctgca caccatacga accggctttg tccatgggct
     5281 gatagtgatc gacataataa gcgatttcat cttcatcaag aatcgcaaaa cggacatccg
     5341 tcacggcagc gaaacatttt tgccattctc gggtagtgag acacacaccg gtaatcactt
     5401 ggtgcgattt accggagagg ctccgcaaca tctctatggc atcctgcctt ccgacaggtt
     5461 tgccgagcgc tttgccttca tgccagacaa tggtatcggc tgtgatcaaa agctcttccg
     5521 gtccgatcat cgactgatag gcggctgcct tctcacgggc tatgaaaaga ggaatctctt
     5581 caccttgcaa cgtatcggga taagattcgt ccacatccgg caaagttttt actacataat
     5641 cgacacccaa gcccgtcatc agctctttcc gacgcggaga attagaggcc aatacgattt
     5701 tataacgatc taagttagca agcatactga taaataaata aggtatatac tggaaatcac
     5761 catccgaaag catcatcgga caaccattgg ccttgtgctt taagcacctg ctccaccaca
     5821 tcgcgtccac agccgtatcc tccatcggca tacgaaatgt aacgggcaat cgctttcacc
     5881 tcgggaaccg catctttggg acagcagggc aatccgcact cacgcatcac ttccatatcg
     5941 ggaacgtcat cgcccatgta gagtatctcc tcgtccgtaa gtccgtgttt gtcacggaaa
     6001 ccacgataat cgtgtatctt caccgcagag ccgaagtaca gatcggatac ccccaacccg
     6061 ataaaacgtt tccgcacgac atcgctccgc ccacctgtaa taatagcgat acgaagccct
     6121 ttttttacgg ccaattggat ggcataaccg tcttttacat ttaccgtacg catcggttca
     6181 cccgacggat gcaaagggat gacattggcg ctcagcactc cgtctacatc gaaagcaagt
     6241 gcctttatcc gggtaaggtc gtaattgatt gtgctcattt ttatttaatg tttcgggatt
     6301 attgtctttc gtgaatgctt cggctaagca actcgtataa ccgctgcatg gcaggatcat
     6361 cggcaagcat ccgcaagtga ttgccgatca cattctcgtc ataacggatg gccggcccgg
     6421 tctgggccgt cttaggttcc agttcgtgca ccttacgggc ggtttcatca atcaacggca
     6481 acatcacgtc aaacggcaga ttgtatttct taagcaactc ggcagcaagg gcatacatgt
     6541 gattggtgaa gttacatgta aacacggcag ccagatggag acttttacgc tgctccgagt
     6601 cggcatcgta cacacggttg gacagtgtag aggcaatggc tttcagaaac gcggcatctt
     6661 ctgccgaaga agcctctatg aagaaaggaa tctccttaaa atctacctcc cgctgcttgc
     6721 tgaaagtctg catgggatag aacacaccgt aatgcgagac atgtccttcc cagacattca
     6781 tcgggatgct acctgccgta tgcaccatca atgcctcttc ccgcttacct tcgacaatgc
     6841 cctgaagaag ttcggcaaag gcggaatctt tcagtgaaac aatatacagc ttcgcatacg
     6901 ggttcacctc tgcgaggtct gtcgtatatt cggcttccac tttctgtgcc agctcgcggg
     6961 ccgactcttc cgtacggcta tacacctgta cgatacgaaa acctttccga tataaggctt
     7021 ttgccagatt agtggcaaga tttccggcac cgataaatac gatcggcgta tcttctatac
     7081 ttcttttcat cgtgttgaaa tcaaatacaa tatacctccg attatcaata aagccaaagg
     7141 cagcagataa ccggacatcg aaccaagcaa cgaaacaatc aggccgatgt tcagcaccaa
     7201 ccacaatccg agcaatacca agccgacgga tttatcccgc ttaataaaca ggaaaatcac
     7261 cgcagtgtaa agcaaaagat tatccttatt catcacccag ggtatcccca aagtggaaaa
     7321 gtgtatcagt ttgtcgatca gatagagcac ccccatcaca ataagggtga ctgctgtggc
     7381 tttgtaggta tctttattgt ttgcttttac cgcactcacc gttacttacc tccgaactta
     7441 ttaatatgga ttttttccca ttgcaaatgg tcttcattaa agggtttacg ttccatccct
     7501 ttatgcccga tcgctatgac ggacaacacc tgcaactgca aaggaatgtc gagcacaccg
     7561 cgcacaaatt catcggaagg catcccggtg gcagtatatc gctcacgcac ctgcacccag
     7621 caacttccca atcccaagtc ttcggcctga agctgaatca taatagaggc aatggaagcg
     7681 tcctcaatcc atacatcgct cgccaaggga tcggcagtaa cgacaatggc caatgccgcg
     7741 tcggcaataa aggccgaagc ctgctctttg caatgtgaaa gttcactgag caacttttta
     7801 tcatcgactg caataaattg ccagctgtta ctgcgctttg aagtaggagc catcagggcc
     7861 gctttcagca aagcgactac atcttcctga gaaagttctt ctccggtaaa tttccgcatg
     7921 ctgcggcgat tttttattag ttcactgaaa ttttccatgt atctatactt tgcattattt
     7981 gaatataccg ccagtcacca tagaatgcac aaacacacgc gaaccgaggt accgcccggc
     8041 atgcccgtct atataaggta tgccctgcag gactttgcat gaatcggcgc gctccgtggc
     8101 gattcgagcg caaagatagg caatttattc cactctcgtc aactcgccgg tcagtgaatc
     8161 gatgataaaa ccatgcaccc ggacatcttt cggaataagc ggatggttct ctatggaacg
     8221 aaccgtgccc ctgacggact tcaccggatc gtcgaatccg cccagccacg aattaaaatc
     8281 gaccccgcag tagcgtatca tgtcgattgt ttcggacttg attccccgct ttttcatgtg
     8341 agctatcatt tcgtcgctgt tcatgtggca agcaccgcaa tcagaatggg caatgaccat
     8401 cacttcttct actcccaact cgatgatagc caccagcaga ctacggatga cactgccgaa
     8461 aggatgggaa atgacggcac cggcattctt tataatcttt acgtctccgt tgtgaatccc
     8521 caaagcggcg ggcaacagtt ctgtcaggcg ggtatccata caggaaagga tggcgatttt
     8581 cttatcagga tacttgttag tgatatactt ttcgtatccc ctgttctcaa cgaacttttt
     8641 gttgaattca agaatttctt ctaacataat caaaaacgga ttttattgta gtatctccac
     8701 aaagatagtc acaaaacgac agctcaacaa aataagccct gcaaatgttg taaagagaaa
     8761 taaaaaatgt aaatttgtcc cgatatgcca ttaaaactga ctacatatta ccaaggaagt
     8821 gagattccgg attttcccgg aaccaatacg tttcattcga aagagctatt tcagatctac
     8881 gaagaaactc cgggctacac cccactcctg attatggctt cggaagacgg aaaacccgtt
     8941 gcgcgactgc ttgctgccat ccgcaaaagc atccgcatat ttcctcccgc tttcatcaaa
     9001 cgctgcgaaa tctatggcac gggcgaatat ctgatagcgg aagccgacaa ggaaaggata
     9061 ttcggcgaaa tgctggagca cctcaccacg gaggctttgc ggaactcgtt tctaatagaa
     9121 ttccgcaatc tggagaacgc catgttcggc tacaaatatt tccggtccaa cagatacttc
     9181 cctgtcaact ggctgcgggt acgaaactcg cttcacggca tcgaaaacgc cgaacagcgt
     9241 ttcagcccct cccgtatccg ccagatcaaa aaaggcctga aaaacggagc aaaagtagac
     9301 gaggcacgta cggtagaaga gatacgcgaa ttttcgaata tgctgaggca tctctattcg
     9361 tcccgcatcc gtaaacattt tcccaacatc atctttttcc aacacatgga cacccggctg
     9421 attcacagcc ggcaggcaaa gattttcatc gtccgctaca aagacaaaat tatcggaggc
     9481 tctgcctgta tctattcggg aaacgatgcc tatctctggt tttcgggagg tatgcgaaag
     9541 acctatgcct tgcaataccc gggtatactg gctgtatgga aagccctcca ggatgcccat
     9601 caaaacggat tccgccacat ggagttcatg gacgccggac tcccatttaa gaagcacggc
     9661 tatcgtgact tcgtgctccg cttcggtggc aagcaaagca gcacccggcg atggttccgt
     9721 ttccgctggc aatggctgaa cgacctgctg atcaaaatat acgtctgaac atccgcctgt
     9781 ctcagggatc agcgccaacc ctctccgtct tttaaaccac cccccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccgggt
    11641 acgggtcagg aatataatgg tgtaatcctt cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatc gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacatt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagctgtca
    12781 gattgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc aatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gaccatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgcc gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattggatt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaatc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat tggtaatgca ggtgtatccg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt tcattagtaa ggtagacgtc cttcttttcg caaagaaggg cgtctttttt
    14701 ttgcgttaat ctatctaaaa gatattacga acctttcgta gaatggatat ttttactaac
    14761 ttgcggacaa taaaacaata cgtcctatga gaacaagaac aatgaaacca ctcttcctta
    14821 ttttctgtct ttgcctcagt cccctactga tgggccagaa tcaaaacaaa attcaggaag
    14881 caatggcaaa ctatgactac gagactgccg ttgaactgat aaacaaggaa cctcccacca
    14941 tcccactgtt aatgcagaaa gcaaaagccc tgaaaggaat cggcagcaat gcggaagctc
    15001 tacgttccat ccgccaagtg atagcggaag actccaccaa ccaacaggca cacatcgaag
    15061 cagcggaatg ctgtaaagca atggccaagt acaacgatgc gctggactac taccggaaag
    15121 ccatcagcct gaatcccaaa aacaagtatg cccgtttgca attcatcaac ctgctttgca
    15181 acaccaaaaa ctatgctgag gcttttggag aaagttcaat gatgtccgaa acggacagtt
    15241 cggccgtagt gctccaccta caggctcaaa gccttgaagg gatgcaacag atactaccgg
    15301 ctatcggttg ctatgaagtc attcaggata aatatccgga cgattatctg gctgcggcca
    15361 aactcggaaa cctgaacatt gtggctggat atcccgaata tgccatccaa gctaccgaac
    15421 gctataggga acgggactcc accaacctga ttgtcaacca gcaaaacgct ctcgcctact
    15481 gccacgccga acaatatccg acagccatca agcgctatga aaagctgtgc caacaggggg
    15541 acagcagtac acagacctta tactacctgg gagtcagcta ttacgcagat gaatattatt
    15601 acgaagcgca cgcgtgtttc agcaaactgc aaaaagagat ggaagaaaat cccaatctgc
    15661 tctattatct gggacgttgc tgcgccaaga cttcctggaa aaaagaaggc atcgaacacc
    15721 tggagaaagc tatcgaactg accattccca aagacagcac catgatccga ctttacaaag
    15781 gcttggtgga ttgttgtaaa ctggctcagg atactccaaa gcaaatccag gctctcagag
    15841 aactgtacaa atatgacaag acgaaccata aacttcttta tgacatcgcc tggaactatt
    15901 catatcaact caaagacaac aaatcggccg aacgttatct gcaggctttc ttaaaaaccc
    15961 gaaaggcgaa tgccaggaaa gaagaaccgg tgagtgagaa aggggaactt gtactcggac
    16021 ttgaaaatta ttacaacgct gccgaaaatt ggctgaaaga cttacagaaa gaaaagttct
    16081 tcaaagaagg aataccgtta gaaagtcaga aacaatagaa tctgtccccc ccatgaaaca
    16141 ttggatactc ctcctctatc tggggttcag cgtagtgctg caagcccaga acaccgcctc
    16201 cgttcaagaa gcaatggcaa actatgacta taaaacggtg atcagactga ttgatgaaga
    16261 aagtgcatca ccacagttac tcatacagaa agccaaagct ttaaaaggtt tagggcgtac
    16321 cgccgaagcc ctgtccactt tgcaacatat cattatcgag ctgcccgaaa atcagcaggc
    16381 attggtagag gcagcagaat gttgcaggca attgagcaaa tttaacgagg ccttggggta
    16441 ttatcggaag gtgatggaac tcaatcccga acatatttac gcacacttgc aatacacccg
    16501 cttgttatac aactatcagc gatacggcga tgcattgcgt gagagtatcg cattggccag
    16561 gaaagacagt tccgccaccg tattgcgact gatggcggaa agcatggaag gagccggcat
    16621 gccggtagaa agtatgtttt gctatctttc catcatcagg aaatatccct ccgactatct
    16681 ctcggtagct aagctgggca gtatcttcaa tacaatgaaa gattacgaag gggcaattgc
    16741 cctgacagag gcataccgcc ggacggacag caccaatgta gaagtgaacc gtcaaaacgc
    16801 actggcgtat tgtctgcgca aagaatatcc caccgccatc aaacgttatc aggatctgac
    16861 cgcccgggga gacagcacac tgctgacatg ttattatctg ggagtcagct actacgctac
    16921 gaaagaatac tataaagcac gcgattggct gctcaaagca aaatcatgcc agtcacccgg
    16981 cgccaaccta ctctactatt tgggacgttc gtgctccaag acattatgga aacaagaggg
    17041 aataggatat ctgaaccagg ctatcgccct gactatcccc gccgacagta tcatggagcg
    17101 cttatactca ggcttggcag actgctacag gcaaaccaag caaacccggg accaaatcaa
    17161 ggctaccaaa gaacaataca aatatgcccc tgacaagcat attttacttt ataacttggc
    17221 gttcttatcg gacaaaattg aagatactaa agccacagag cattacttgc aggcttttct
    17281 gcgaacaaaa tccaaacaaa atgcagtact acagcagccg gatgatgacg aagaagaacc
    17341 cgcaccctac atagattact acaaaagtgc caccaataaa ttggaaagca tccgaaaaga
    17401 gaaattctta aagggagaaa agtgaattga tcggatagat gcatcgtttc ggacaattca
    17461 ccactgagtg cagacagagt ttcacagagg gagaataatg gaaaataaat ttgaagatgt
    17521 gcggtagaag gcacagtggc acgtaaccga agtcacatcg gcacgcagcc gaaattacgg
    17581 tgctgtatag ctaaagttac ggtgctgtgt agataaagtt acggtgctgc gtagccaaag
    17641 ttacggtgct gcgtagataa agttacggtg ctgcgtagcc gaagttacgg tgctgcgtag
    17701 ataaagttac ggtgctgcgt agccgaagtt acggtgnnnn nnnnnnnnnn nnnnnnnnnn
    17761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17821 nnnnnnnnnn nnnnnnctgc gtagccgaag ctatgacggc atctcctttt ccggacgtca
    17881 cgttcacctg attgcatcga aaagtgctcc ttatcggttg agctccatcc cggagaattc
    17941 tccaatgaaa acgtttgcat aaatagatgg cacacagtaa gaaagaaaac ggaaaacaat
    18001 ccgatgattt accctatatt agcaacatta aataataacg agctaatatc atgaaaaaat
    18061 tattgttact cttaggttca ttcctactgt cattaaccac ttatgcagcc atgaacatat
    18121 ccaaaatcga tccgccctgc tggttcaccg gtatgaacaa tccggaactc cagttaatgg
    18181 tatacggtga aggcatcggc caggcatccg tatcagtaaa ttatcccggt gtatcgctca
    18241 gcagcatcgt gaaactggaa agcaacaatt acctgcttgt ctacctgcat ctcgataaag
    18301 aagtaaagcc gggcaagatg cccatcacat ttacggtcgg aaagaagaaa ttggtgaaag
    18361 agtacgaatt gaaagcacgc agcaaagccg gagtcgatca caaaggtttt gacgcatcgg
    18421 atgcattata cctgctgatg ccggaccgtt ttgccaatgg caatccggat aacgaccgga
    18481 tagaaggcat ggccgaatat aaagtggacc gcaacgaccc gaacgcacgt cacggaggcg
    18541 acctggccgg tatcgaacaa aatctggact attttaccga cttgggagtg accgcactct
    18601 ggttcacccc ggtactcgaa aataatatga aaggcggctc atatcacgga tatgcaacaa
    18661 ccgattatta caaggtagac ccacgtttcg gcactaacga ggaatatcgc tcactgatag
    18721 cgaaagccca caaccggggc attaaggtcg tgatggacat gatcttcaat cattgcggag
    18781 tagaacatcc ctggatcaag gacatgcctt caaaggactg gttcaaccat gcggacttca
    18841 agaacaactt tgtgcaaact tcctacaagc tgactccaca tgtagatccg tatgcctcgg
    18901 agtacgattt cgaccagatg aacaacggct ggttcgtgga agccatgcct gacctcaacc
    18961 aaaagaaccc tcacgtatac aaatacctct tgcagaacag cctgtggtgg attgagtacg
    19021 ccgatatcga cggcatccgg atggacacct acccgtatgc cgattacgat gccatgagca
    19081 actggatgaa agaactgaac gaagaatacc ccaactacaa cacggtgggc gaaacctggg
    19141 ttaccgaacc ggcctataca gcctggtggc agaaagactc caaactctcc gccccgcgca
    19201 acagtcactt gaaaacagtc atggatttca gcttcttcga caaagtcaac acggccaaga
    19261 atgaacaaac ggacacttgg ttcaaaggat tggaccgtgt ctacaacaat tttgtatacg
    19321 attatctgta tcccaatccg gcttccgtac tggctttcat cgagaatcat gacaccgacc
    19381 gtttcttggg tgaaggcgaa aacctcgata tgctgaaaca ggcctccacc cttttattga
    19441 ccacccgacg catcccgcaa ctctattatg gaacggaggt gatgatgaac ggagtaaaga
    19501 gtaaaagcga cggctatgta cgaaaggact tcccgggcgg atgggcggac gataaagaga
    19561 atgccctgac tcccgaggga cgtacccgat tgcagaatga aagctataac ttctaccgca
    19621 acctgctgaa ctggcgtaag ggcaacgatg tgatcgccaa aggcagcatg aaacagttca
    19681 tggtgcagca cggcgtatat gcttatgcac gccaatataa agggaaaacg gtattcgtcc
    19741 tgttgaacgg tacggataaa gaggtgaaac ttcccctgaa atactatgcc gaagtgctga
    19801 aagacaagac tcaaggaaaa gacgtcatta gcggaaaagt aacggcactc aatgaagaac
    19861 tgacaatggc accccgccaa tcgatggtta tagagcttta atctcacacc ggttataacc
    19921 gcataagcaa agggcacaaa ggatttcacc cgacatcctc tgtgcccttt gtgtagccta
    19981 atgcgaataa taatagttaa acgtttgact attatcggag aatattccta cctttgcacc
    20041 gactaaaaga atacgacgat gaccaataac gaatcggcac gcgagctcgt cctacaaacc
    20101 ttacgaaccc ggatggcatt ccgccaggcc gttcagcggg tactcaaacg tcacaacgtg
    20161 gatatgacct tcgagatgct gcaagtaatg aactgcctgt ggaacaaaca aggcatcagc
    20221 cagcaatccc tggctgagaa aacagcaaag gacaaggctt gcctgaccaa tctgattaat
    20281 aatctggaaa agaaaaactg ggtgatacgg aaggaaggcc cctccgaccg ccgaaaccgc
    20341 ctgattttcc tgacacccca aggcgaagaa cttgccctca ccgtgaaacc cctgatcaac
    20401 gatatctatg cccaaaccgg agcagagatg gaggcaagcc ggataacgga atgcatcgaa
    20461 gacctgaaga gactgcatga agtgctcaat gagatctaaa agaaatccgc catgtccacc
    20521 cgtcagataa agctaaaaca attgagaaga ctgaagttca ggaacatctt tctcaacaca
    20581 gtatgcatcc tgctggcatt ggcaggtatt tcatggacag taaactactt ctggaaatac
    20641 gcccgctacg agataaccaa tgatgccgta gtggatcaat acatcgctcc gctaaacatc
    20701 cggataccgg gctatatcaa agaagtacgt tttaccgaac accagtatgt tcatgccggc
    20761 gacacgttac tgatactgga cgaccgggaa taccggatcc ggctgaaaga cgcggaagcg
    20821 gccttgatgg atgccttggg atcaaaggaa gtgttaaact ccggcatccg gacttcagga
    20881 gtaaatgtag ccgtgcagga agccaacata gccgaaacac tggcacacct ttcacagcaa
    20941 gaagcggaac tgaaccgata tacccggctc ctgaaaaagc aggccgtcag ccaacaggat
    21001 tatgaactgg ccaaagcgaa cttcgaagcg acccgggcaa gatacaacgc cctgttgcga
    21061 caaaaagaag cggcccaatc gcagtattcc gaaaccagca aacgcagtac aggcgccgaa
    21121 gccaatatcc tccggaagga ggccgacctg gagatggccc gactaaacct gtcgtatacc
    21181 gttgtcaccg caccctatga cggatacacg ggacgacgta cacttgaacc gggacagttc
    21241 gtacaaggcg gacaaactct ttcctacctg gtacggggca atgacaagtg ggtgacagcc
    21301 aattataaag agactcaaat agcccatatc tatatcgggc aaaaagtccg catcaaagta
    21361 gatgctttca gcggacgcac ttttcacggg accgtaaccg ccatttccga agccaccgga
    21421 tcgaaatact ccctggtacc gaccgacaat tcggcaggaa acttcgtcaa agtgcagcaa
    21481 cgcattccgg tccgcatcga tctcaatgac gcctcacccg aagagatgga atgcctccgt
    21541 gcagggatga tggtagaaac ggaggcggtc cgcccttagg cttatggtga agctcaatct
    21601 gcctacccgt ccctgggtgc ctcaatggtt gggcatcgtg accatgttta ttgtcatctt
    21661 tcccatcacc ctgctcaacg gtgcctacac aggaagtatg gtcgaagtat cgaacacgct
    21721 gggagtattg agcgaagata ttaccatggc ttactattca gcttcggtag ggatggctgt
    21781 tgcctatccc atcgtaccga aaatacgcac catagccact ccgaaaacct tactgcttac
    21841 cgacctgctg ctacagatat tcttcagcct ggtatgcgcc aaaaccggta gtatggacgt
    21901 catcatggta tgcagtttct gtatgggatt tctcaaagcc ttcgtcatgt tggagttcat
    21961 catcctgatc cgcccgctct tcagtccgaa aaacgtacga agtgaatttt atgcctactt
    22021 ctaccccatc gttttctccg gaggtcagct atcgatggct atcaccgctc aactggccta
    22081 tcactaccaa tggcagcaca tgtactattt tgtcaccatc ctcttgctga tcgcccttct
    22141 gttcgtcatc tgtttcttcc gctatgcaag gcgtcccatg cacattccgt tcaaagagat
    22201 ggacggaaga agcatgttca tcatcgccac cgctttcctg ctaacgctct atacatttac
    22261 ctacgggaaa acactcgatt ggttcgcatc cccgaagatc agagtatatg tattcgtcat
    22321 cccgctcctg atagttctct tcatccatcg gcagcgtaca caaggcaaac cctttgtcag
    22381 cctgaaacca ctctttctgc ataaatccat catcggatat ggcttcatgg tactcgccat
    22441 gttcctgaca gccaccagtt cactggtaac caactatatg aacagcatca tccgggtaga
    22501 cagcatacac gccaattcgc tgagcctgtg gctattgccc ggatatgtgg taggagccgt
    22561 catttgcttc tggtggttcc gatggcaacg atggaggttt cgcttcctca tttcaggagg
    22621 tatgttctgc tacgtcatct atctggctat cctctacttt ggtatcaccc cttatggaac
    22681 ttatgaaatg ctctacctcc ccatcctgtt ccggggagtg gggatgatgg tcatattcat
    22741 tgcgttcggt gtgtttgttg tcgaagattt agacccgcgc ctgacgttgt ccaatgcctt
    22801 cttcctgatt tcattccgct cagtattggc tccggtcctg tccgcttcgt tctttaacaa
    22861 catgctttac tatctgcagg caaaggggat gaacattctt tcggaaaaca tgacgctgac
    22921 caatccgctg gccgaacaaa aatacaatca ggcattgagc aatgccctgg cgcaagggca
    22981 cgaattcggc gaggccggac aattggcagc caacagcctg tactccactt tgcagcagca
    23041 atccctgctg cttgccctga aaaccctgat cggctatgta ctgatactgg cactggtgat
    23101 tgctgtcatc gcagcgttca ttcctttcca taaaacgctg aaggtggctg tagtgaagac
    23161 gggtgacgat atggtataat gagaagggat acaaaaaagc cacccaattg cttgagtggc
    23221 ttcttaaaat ataaattaaa tcaagtaaaa cttttaaata ctagatttgg aatttattca
    23281 gctaacttgt tgtcagaacc cagcacgttg ataattttgt gcttgtagag tttttccata
    23341 ttgtcgcgag ccggtcccag atatttacgc gggtcgaact cagccggttt ttctgcgaat
    23401 accttacgga tagcagcagt catagccagg cgagagtctg agtcgatgtt gattttgcaa
    23461 acagcagact tagcggcttt acgcagttcc tcttcaggaa taccgatagc agctttcagt
    23521 gcaccaccaa actggttgat agttgcaacc tcttcttcag gaactgaaga tgatccgtga
    23581 agaacgatag ggaatcccgg aagttctttc attacaccgt ccaatacgtc gaatgccaac
    23641 ggaggaggaa ccatacggcc tgtcttcgga tcgatgtggc actgttccgg agtaaatttg
    23701 taagcaccgt gagaagtacc gatagagata gccaatgaat cgcaacctgt cttggtaacg
    23761 aaatcaacta cttcgtccgg ttcagtatat gtgtggtggt cagaagaaac ttcgtcttct
    23821 acacctgcca atacgccaag ttcaccttct acagttacat cgaactggtg agcgtattca
    23881 acaactttct tagtcagagc aacgttttcg tcgtaaggaa ggtgagaacc gtcgatcatt
    23941 acagaagaga agcctgagtc gatacagctt ttgcaagttt cgaaagtatc tccgtggtcg
    24001 aggtgcaaaa cgatttcagg atttttgcag ccgagttctt ttgcatattc tacagcaccc
    24061 tgagccatgt aacgcaacaa tgtagcgtta gcatactgac gagcaccttt tgatacctgc
    24121 aaaataaccg gagacttagt ttctacagca gccttgatga tagcctgcat ctgttccata
    24181 ttgttgaagt tgaatgcagg gattgcatat ccacccttga tagccttagc aaacatatct
    24241 ctagtgttta ccagacctaa atctttgtaa ttaaccattt tgtttaaaag tttattgtta
    24301 gtgaattaaa aattctatgc aaaagtaaga ataatccttt gaatagagaa accctcgggc
    24361 ggaaatatcc gtttgaggag cgtaattcaa ttctatttca aattatttcc catcctttaa
    24421 gagctgtttg taatgtctac gtagcaaata aaggtttttt attgtttcct catatatata
    24481 atggtaggca aatgatcgct gtaaccatcc aaccacactc tgccaccata tgtacgcagg
    24541 ggtgcaccct tatatttacc atcctgctga aacaggtaat cgcgcatgaa aacttcattg
    24601 tgatcatatt tcaatccttt tgtggcttga agcagcgtg
//
