LOCUS       gnlProkkaAIGJNPKI_526  13473 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIGJNPKI_526.
ACCESSION   gnlProkkaAIGJNPKI_526
VERSION     gnlProkkaAIGJNPKI_526
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:12:18
            Original ID  :: gnl|Prokka|AIGJNPKI_526
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13473
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13473
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3128:3473]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3129..3473
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13473
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13473
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             83..1594
                     /locus_tag="ctg526_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVEADVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             1668..2732
                     /locus_tag="ctg526_2"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             2754..3035
                     /locus_tag="ctg526_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(2983..3108)
                     /locus_tag="ctg526_4"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKRLPTGGQHILSVRP"
     CDS             complement(3129..3473)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg526_5"
                     /sec_met_domain="PF05402 (E-value: 6e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.5e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             complement(3517..4905)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg526_6"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5196..5591)
                     /locus_tag="ctg526_7"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             complement(5598..6392)
                     /locus_tag="ctg526_8"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6397..6924)
                     /locus_tag="ctg526_9"
                     /transl_table=11
                     /translation="MNWIKKIARPLILIVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(6911..8152)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg526_10"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8276..9370)
                     /locus_tag="ctg526_11"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEARYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9375..10412)
                     /locus_tag="ctg526_12"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFDCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTREA
                     EPTNK"
     CDS             complement(10430..11467)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg526_13"
                     /sec_met_domain="PF04055 (E-value: 1.4e-17, bitscore: 54.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSKYPLLGMTLIELQSLVKRLGMPGFAAKQIASWLYDKKVTSID
                     EMTNLSLKYRELLKQNYEVGAEAPVEEMRSVDGTVKYLYPVGENHFVESVYIPDDERAT
                     LCISSQVGCKMNCKFCMTGKQGYSANLTAHQIINQIHSLPERDKLTNVVMMGMGEPLDN
                     LEEVLKALDILTGSYGYAWSPKRITVSTVGLRKGLRRFIEESDCHLAISLHSPVTAQRA
                     ELMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCR
                     MNLIRFHSIPGVALEGADMDTMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQE
                     ENNKS"
ORIGIN
        1 aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa gtttgtgcgt
       61 cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta agaagttaga
      121 tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggagc gtgccgcaca
      181 ggcgctgact aaagccatca ccaacagatg gaatccggaa acacctgtca ccatctttgc
      241 cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg cggaaaaagg
      301 atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg actgccagac
      361 caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca gcacccagtt
      421 cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg gttccggact
      481 caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg cctctcccgc
      541 catggtagtc tccatcgaca tcccttccgg actgatggga gaagaaaata cattcaatgt
      601 aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta aactggcctt
      661 cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca tccagctgag
      721 cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg aagaaatccg
      781 ttcactgatc aaaccacgcc aacaattcgc ccataaagga aacttcggac atgccctgct
      841 gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcccgtg cctgtctgcg
      901 atcgggagta ggtctgctga ccgtacacgc gccgttatgc aacaacgata ttctgcaaac
      961 gtccgccccc gaagccatgg tagaagcaga tgtcagcgaa acatgctttg ccgtacctac
     1021 cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca acgaggaaac
     1081 ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac tggatgccga
     1141 cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga aaggttccat
     1201 cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg actcatacga
     1261 acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca ttctgaaggg
     1321 agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga ccggtaatcc
     1381 cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg cactccttgc
     1441 gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg gattggccgg
     1501 agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata tcgtgacctg
     1561 tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg gtttattcaa
     1621 taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg aaaaagttaa
     1681 tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa gtgctgacag
     1741 gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc cagatagaaa
     1801 tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa tatgccgacc
     1861 gctacctgag actaaccaac gtctctgccg aacccgaaga atactgggaa ttgaacagcg
     1921 tcaaggtgaa gcctgtaggt gtaccaaaca gcgaagccac ttatttcgtc aaactgaaag
     1981 acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa tcaatcaacg
     2041 tcccctacag cagcaacaat gcaaagaatg cagcaaacaa tgccgttgct ccccaacgaa
     2101 aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca accgccaaga
     2161 tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac gcattattgc
     2221 gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg ctcgacaacc
     2281 tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat aaagaagaaa
     2341 agacatttac tgtccgcctc actccggata aggaattcga caatgaggta gctttccgct
     2401 tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca ttctacatca
     2461 gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cggaaaaaag aagaaagaga
     2521 tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg gacggcaaaa
     2581 agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa taccttgctc
     2641 cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg accggtggac
     2701 tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa acgatgggtg
     2761 gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa gcctcccgct
     2821 tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac gacccttatc
     2881 ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg gaaaagaaaa
     2941 aagaaaaaga taacagctat ttcgtatggg gaacgctcat cattatgggc gtactgatag
     3001 gatgtgctgt cctcctgtgg gcaatctttt tttaatggat aatggaaaat tgataatgga
     3061 taatgaacgt atgggataat attccagctg ctcaacctca ttatccattt tccattatca
     3121 attatccatt aatcaattat ccatttaata aatccgtctt tctgtaattg ggaaagatag
     3181 gtagatacac gagactcgta gcctgcttca tgctgaaagt ggtctgcgag tttttctata
     3241 atctcacgaa ccgtccgctg gccgtctatc aggttccata cggccgtacc gtgttcttcc
     3301 agacgcacat gaatatcttt ggacattcct ttcggcaata aataacgact catccacgaa
     3361 cgtttaaaac gagggaagga gagcacaata gtctcccctt cctgttcagc tttaatatgt
     3421 tcgttacgac aagggatcac ctccaggagg tttattttct ctttcgtagc catatctttt
     3481 ctcttttata tcttttcaga tagaatatat actggattat ttctgaatat ttgcttcttc
     3541 cagtccgtag cctttcttct tgttttctgc tttcagcatc aaggcaacaa tcagggcaag
     3601 tacaccgaac atagcaaaaa tagccatcgg caaggtataa tcataagtct gtgcaccatc
     3661 tacaaccgga cctttgcaat aagaattcaa cacccatccg atcagcaaag gcacgcccat
     3721 caatccccag ttctgtaccc aaaagatcaa cgcataagcc gttcccaact gtttctccgg
     3781 aataatcttc ggaaccgaag gccacattgc cgaaggaacc aatgagaaag caaatcccag
     3841 aataatcatg atcaccgttg caaaccacca tatattcaga ataggaagag cgaacatcgt
     3901 gtgtacgaaa atcagcatca ccgacccgat caccatcagc gtggctccct taccgatacg
     3961 gtcatacaat gaaccgaaca acggtgtcag gatgatcgcg ccaatcggca gcaatccggg
     4021 aatcgttccc gcaagtttcg gatcaacatt gtacttctgt accatcaaat cggccgcata
     4081 cttgatgaag gggaatacag ccgaatagaa caatacgcac agtaatgcga tcagccagaa
     4141 tcctttgttg gtaatgatat agacaatgtc tttcatgcgg aaaggttctt ccggttccag
     4201 tccttccgca tccagtgaag catccagttt cttatcgtag aaagtataga tgaagaatgc
     4261 gatggtacct acgcacaaca tgacgagaca gaacagaatc ggagcgggaa tattggtatg
     4321 gaatacgccg ctctcatccg tagacccgaa gaagtctgcc aaaggaacgg taagcaccat
     4381 ggccaaagtc gttccaatac gcgcggtcgc catttccagt cccatagcga gagccatctc
     4441 tttgccttta aaccacttca cgataatctt cgaaacggtg atacccgcaa tttcgactcc
     4501 tacaccgaaa atagcataac ccaatgcagc caatgtgact tgcatcttga atccgaaaag
     4561 catcgcacct tccgggaaag tagtagtaat agcataatat ttcaatccac aaccgaacac
     4621 catcaataaa caggcaccca ttccggtgaa gcgtactccc atcttatcca gaatgatacc
     4681 accaaagatg agcatcagca ggaatacatt aaaccagcca taagcactgg tgaaaaaacc
     4741 gtaatctaaa ctgtcccaga gaagttcttt ttcaagcatg ggtttcagag gagacataac
     4801 gtctgtgagg aagtagccgc acaacatggt aaaagcgact aatgctagaa cactccaacg
     4861 cagcactgcg gagtcattca gcttttgttt caattgttct gtcattgtaa tatttaaaag
     4921 gagttaataa tctcgtaacg ggcaacaaag ttaactaatt atcatttgtt ttactaaaaa
     4981 aggagaacat tttataagaa aaaggacatc tgaccggata ttcctgtatg aagaagagca
     5041 gaccgggccc aataataaag acaggcgcga actacacgta ttacacgatt ctattagaat
     5101 ctcttgtaat tcgcgtaatt cgcgcctata atgaagagaa cgggtcaaaa agcccgttca
     5161 ctcaataagt ttaaaccgaa tatcctgtca ctgaattatt ctgctgcagg agcaggagtt
     5221 tcagtagccg gagcttctgt tgctggtgca gactctgcag gagcagtagc gtctgtctga
     5281 ggagcagcag taccggtagg catattatac ggattggttt gttgttcttt ctgtgcttgt
     5341 tccaacaata catctttagc tgcagaagaa gaaggaacaa cgtaagcagt agcaacgctc
     5401 atcacaacca tgaagatagc cagaccccaa gttgcttttt ccagaaaatc tgtagtcttg
     5461 cgcacgccca tgatagcgtt tgatgaagaa aaaccagaag caagtccgcc tccttttgaa
     5521 ttctgaatca gcacgatgaa gcacatcagc aaggctgcaa tcaccattaa gataatgaat
     5581 aataagtaca tttttagtta ttttgaatta gcgttaataa tcaatttctc caaaaatctg
     5641 atttggtctg caaagtaagc attttttttt ggatatttca agcttaattt tttaattatt
     5701 tcaagagctt tcgaatatcg ttgctgtttt acgtagattt tggccaaagt ttctgtgaaa
     5761 cagctgtcat cttcctcttc tatggtgttg gtttcagttg tttcgtctgt tctgcccgtt
     5821 tcgtttgttt cagcggaaga agctgccttt gctttctctt cttccctcaa aggtttcagg
     5881 tatacgactg gatcagtctc gcttttttcg ataaagttgt caatcagctc gtgtcctttc
     5941 agcttgggca ttgcctctgc cggctcgtcg gcgacaggtg tctcttcgag aaggtatgcc
     6001 gtatagtcca tggagtaatc aaagcttgtc tgactggtta cttcttcggg agccgtcgaa
     6061 aggaaagcat cgatcagagc cagtgtccgg tcgacggtag gctcatcttt caatacttca
     6121 gagagaggca accctttctt ctgggattcg acagcgaagc gttcgccttc gatcagatga
     6181 aacagtttcc gtcggtcggc aatatacaga acggctttcc gcagttccgc accgaaatta
     6241 atgtcgtgga gaatatacag gttcttgaga tacaacaacc ggagcgactg aaaatacgga
     6301 tacctcgcga gctggttgcg cagttcgtac aaagtatccc tattcagcgt ctcgggatgc
     6361 tgaatccatt gttgcaagtt aacagaagtc attaaattac cagtttgcta cagttgcatt
     6421 aaatatttgg tcggttatct ctttactcat ttccgctatt aatccatcct gtacggctgt
     6481 cagcagctgg ctggaatcat aggtacggaa agctgagaat tgttgttcga agtcttcggc
     6541 gtgatttgtg ttgttgacaa agcgtacatt gaccgtgatg gtcagcttcg tttccgaaga
     6601 gtaaccatcg gcagacactg cctggttata ctggttgtag cccgtaattt caccgtcaat
     6661 ctgcagatcc gcattctggt tcggtttcag cagttgcaga cgggtctgtc tgatgaagat
     6721 atctttcagg tcttcattga acttggtagc cagcggagca tacacatact ccgacttaat
     6781 cgggaaatca gcaatcgaaa tggtcttcac cttatcgtaa ttgatagagg agccattaaa
     6841 cttataggac acactacagg cgatgatgac tgccggtaaa acaatcagta tcagcggtcg
     6901 tgctattttc ttaatccaat tcatattctt ttatttttct gtaaagggta cgctcggaga
     6961 tattcagatc cttcgccgca cttttccgct taccatgatg cctctcaagc gctttacgta
     7021 tcatttcttt ttccacttca tcgagcgaaa gggtttcttc tacatattct tccgtgtcct
     7081 gaatatcgtc atcgtcttct ttgggacaaa cagacggttg ctgcacagca tggataatgg
     7141 ccggcacgga aggttggtgc gtcgttgtca ctaccggagt agctactacc tgtcccatct
     7201 gtccgacttg tcccgcacgt tcagccatca tattgtgcac catcttcttc agttccgcca
     7261 cttcctgacg catatcgaac aagacagaat atagtatttc gcgttcgctc tcaaagctct
     7321 tgctctcgcg tgtgccgaac agtgccggaa ggcgttgggt attctgtgcc ggaagatagg
     7381 tctgcagaat cgcagccgtt atctcacggt ttgtttctat aatcgaaatc tgctctgtga
     7441 tgttcttcaa ctgccggacg tttcccggcc acggataagc aagcaatatc ttcttggcat
     7501 cttccgtcag ctggatagcc ggcatccggt acttttcggc aaagtctgcg gcaaacttac
     7561 ggaacaacaa cagcacatca tctccacgct cacgcaaagg tggtatctga ataggcaccg
     7621 tgttcaaccg ataatacaaa tcttcccgga agcgtccttc ggcaatggct tgtgtcaggt
     7681 tcacgttggt agctgccaca atacgtacat ccgtcttttg tactttggat gaacctacct
     7741 tgataaattc accgctttca agtacacgga gcagacgcgc ctgtgtaggc aacggcaact
     7801 ctcccacttc atcaaggaag atagttccac cgtcagcttc tccaaaatat cctttccgct
     7861 caccaatagc accggtaaat gctcctttct cgtgtccgaa cagttcggaa tcgatcgtac
     7921 cttccggtat ggcaccacag ttgacagcaa tatactgccc atgctttctc cggctatatt
     7981 gatgaatgat ctgtggaaaa ctttcttttc cgacaccact ttctccggta atcagcacag
     8041 acaaatcggt aggcgctacc tgaatggcaa catctatggc acgtgataaa gcctcggtat
     8101 tgccaataat accgaaacgc tgtttcactt gttgtatctc cgctttggtc atctatctta
     8161 atattaagta ataggtaata agtattaagt aataagtatt aagtattacc atcattatca
     8221 tctcgcttcc atccgcatgg ctaatactta atacttatta cttaatacct attacttaat
     8281 cttcgtctac tgtatccagt tttagtttat cactatcgtc ccgtttctcg taatactgct
     8341 tccgcaacgg gtttacccgt gccgctttct cgcgctggcg gttgcggaat acatcaatcg
     8401 ctacataaat agcctggcgg aaagagtctt cgctggccag tcctttaccg gcgatgtcat
     8461 aggctgttcc atgagccgga gaggtacgta caaccggcag tccggcggta tagttcacac
     8521 cgtcttccat agccagggct ttgaacggag ccagtccctg atcatgatac atagcaagga
     8581 ttccgtcaaa gtgagtataa ttgcccgaac ccataaaacc gtccgcagca taaggaccgt
     8641 aacagatgat ccctttctct tccatttctt tcatggcagg gataatgatt tcctgttctt
     8701 ccatacccag cagtccgccg tctcctgcat gaggattcag tgaaagcact gcaatacggg
     8761 gcgcaccgat accgaaatcc tgtttcagac aacgatggaa aatcatcagc ttttcctgaa
     8821 tcagttcctt ggtgattgtt gtagcaatct cccttaccgg aatatgcgtc gttactaaag
     8881 ccacacgaaa atcgtttttc atcaggatca tcagtgactt gtttccattg cccagacgtt
     8941 cttcaatata ctccgtatgc ccggggaaag agaactcttc cgactgaatg gtatgtttgt
     9001 tgatcggagc tgtcacaatg acgtcgatca gcccctcacg atactcttct atggcacgct
     9061 ccaaagcacc caatgcagcc ttacctgctt cgggatcggg tttggagaat tccactttca
     9121 cttcgtcatc tgtacagttc actacactca gacggttgta tctggcttcg gaagctgtgt
     9181 tgacaatgct gaaattagcc tgtacatcca gtgctttacg atggtaagcc gctactttag
     9241 gtgaaccgta gataatcgga gtacatagct caagcatggt agggtctgag aatgtcttca
     9301 agatcacttc ataacctacc ccgttgatat ctccttgggt aatgccgatt cttattttgt
     9361 tttcttccat gtttttattt attagttggt tccgcttctc tggttacccc cagtggaatc
     9421 tgactctgct gaccttcttg cggaagtttc agcgtataaa gagatgcttc catctggcga
     9481 accagattgc gtttcatttt atcgggtgaa tatacaaata tttctgctgt aataatacgt
     9541 tggttcttct gatccagacg agtatgggaa acgaatgggc cacccatgaa gtcacccttc
     9601 atgcgccaca atccacgagc ttccatcgtg tagtcattgt gcacgttgat cggacgaaca
     9661 tcggtcagta acgagtctgt cgacatatat acgccttctt tatatccggg gatattggct
     9721 ttcatcacag aatcgcgctt atgaacaaag tattctttgg tgaatgtatc cttgtcagta
     9781 taaggataag aatacatcac gaaattgcga tccgcgctgc ctgtattggt agatgcccaa
     9841 aagaagtcct ctcctgtctt ggagttattc agttcggaag gtatccagat atcgcagtca
     9901 aacagactat ctaccttatt tgagataaag ttgttgtgct tttcctccag caaagtaatc
     9961 tgacggttca tttcagcgcg agtgaagaag tcgataatcg tctgcttgtt ttcttcgaca
    10021 aacttctcaa acacttcttc gttcggagcc tgaatggtca gtatcatctg tggagaagca
    10081 taaacgtctt tcgcatactt gaaagtacct ttggtataaa tatcttttat atctactatc
    10141 acaatattac ggatcaactt cagcgtagaa tcatagtcct tcggtgaagt atacataatc
    10201 cggaaagaag gttccgactg gggcagtccc ggcatgtcag aatcaagcac atcatgcaag
    10261 gcccttccgg cggcacggtc ccacactccc gcatctacta caaccaacag ttcatacgga
    10321 cgaccgctag aggtatgatt cccctttaat ccacaagaag caactacgaa ggctaccaga
    10381 gccatgctta aataaaaaaa gtactttttc atgatgttcg atttttatat taacttttat
    10441 tattttcctc ctgtttcgca gtcgacagca taccgcatgc cgcaaaaata tcctctcccc
    10501 gcgaagcacg aatggtagtg aaaagcccgt gcgtagtcag atagtcacgg aaacgggtca
    10561 tcgtatccat atcggctcct tcaagggcta ctcccggaat agaatggaaa cggatcaggt
    10621 tcatccggca atccagtccg cgaagcagtt tgagtaactc cttggcataa acttgcgaat
    10681 cattaagccc cttaaaaaca atatattcaa acgaaagtcg acgctgtttg ctaaaatcat
    10741 agttttttaa cagttccacc atttccgtga tagaaaaggc tttctccgcc ggcatcagtt
    10801 ccgcacgctg ggcggtcacc ggagaatgca ggctgatggc aaggtgacag tcgctttctt
    10861 cgataaagcg ccgcaatcct ttccgcaatc cgacagttga aacggtaatc cgcttcgggc
    10921 tccatgcata accataggac cctgtcagta tgtccaatgc cttcaacacc tcttccagat
    10981 tatcgagcgg ttcgcccatt cccatcatga cgacattcgt cagtttgtcc cgttccggca
    11041 aggagtgaat ctgattgata atctgatggg cagtcaggtt ggcagagtag ccttgtttcc
    11101 cggtcataca gaacttgcag ttcattttgc agcctacctg cgaagaaatg cataaagtcg
    11161 cccgttcatc atccggaata tacaccgact ccacaaaatg attctcgccc acagggtaca
    11221 ggtatttcac cgtaccgtct acagagcgca tttcctccac cggagcttca gctcctacct
    11281 catagttctg cttcagtaac tcccggtatt tcaacgacaa gttagtcatt tcatcaatcg
    11341 aagtcacctt cttatcataa agccaggatg caatctgttt ggctgcaaag cccggcattc
    11401 ccagacgttt caccagtgac tgcagctcta taagcgtcat tcctaagagg ggatatttag
    11461 acatcattct ttctgttcat ggtttatatt tgcaaatgta aggaaataaa gtcgatttcc
    11521 gtatagcaag gatgtaaaag ttagcaaaaa aggtcgttcc aaagcatgga acgacctttt
    11581 gcagttatcg tttttacgac taatcttaga agaacaggta acgtgtatcc ttcacttttc
    11641 ctttcagata caggtcgttc atcagacggc ttgcgaagcg tgcgtgcata ttagccaatg
    11701 tagcttcttc atctttagcg ttaaaagtat cgctcagttt gtctttgcca tacatctgaa
    11761 gcacaaatac accggcatta cctttgattg gagcactcag tttgttcatt tcagccacag
    11821 aagcataagc acctaccagc ggttcgctgc tgcgcaattc agagacataa gcgggagcgg
    11881 caaatgtaac cagcttcaaa gaatcgctga ctgcgccggg catagccttg tactggtcga
    11941 gagaagttgc attggcagct ttcatatcag ccatgatctt ttcggctttc ttatctttaa
    12001 cgatttcagc tctcaactga tcctgtacag ctttcagcgg acgatatcct tccggagtaa
    12061 caccaaccag agctactgca accatatggt cgctttcgcc acattcatac aaaccggaaa
    12121 catcacccgg tttagcggaa aatgcccatc tcaatgcttc tttagtacct cttacaccac
    12181 cgatagtatg ttctgagcta tacaagtctc ttctgtcaag cagtttgtat ccggcttctt
    12241 cagcgttagc gatcatcttt tcagcagtag gattggcagc gatgaactgg ctgaagtcat
    12301 tgtaagcacg gttataagtt tctttgctga attcaacttc acgtttcaca acagctactt
    12361 tatatttatc cttcacagct ttcttgttag tcacctgcag gattacatta gcttgtccca
    12421 acggcaggtt tactacttcg ttcacgcctg tattattgat agcagagata aacttcaggt
    12481 tgtcaccatc gatctgtgcg ccttcatact gtgcagagct catccagtta gtctcacccg
    12541 tctgaccgta tttcttagcc agatctgcga agttagcacc gcctttgata gcagtataga
    12601 tactgtccgc caaggctttt gtcttcaaag cgtcttctgc aaacacctga atctgacgga
    12661 actcgattga gtcggcagca gctgtttttg caaccacttt gaatgaatta atagtattgt
    12721 cggcaccatt atagtacgga ccataaacag aaccaacgga tgcagagtcc agacgggcaa
    12781 ctacatctga cgggaaagct gttttattat agaacaagtc tacataagga gcttccgagc
    12841 ctacagagcg gataaaagaa gtatagtcat ctgttgtagt agccaactgt gcagtagctt
    12901 cgtctacttc ctgctggata gcagctctgt cttccgcact tgcagtcacc tgaacatcaa
    12961 tgtacttgat atcacggctt tcctgatatt gcttgaactg ttctttcttc ttgttataaa
    13021 ggtctttcag ttccgattct ttcacaacga ttgtagaatc tactatagaa gaataaggaa
    13081 cggcagccat caacaagtca tattgattca ctcttgcgtc gaaagcgtcc tgtgcttcta
    13141 ccgggttaga gagaagcgct tttgctacca atgcctgata tttttctgcc aggcggctct
    13201 gaaccaatgt cttctggatg aatgaccagt atttgtacat gttgttgtac tgttctgcat
    13261 actgagccgg catctgagat tcgttcattt tagcgtaatc taccaggaac ttattgagca
    13321 tatccttatc gaaagcaccg gtctgcgggt tgcggaaagg agtctgttgc aacaacggat
    13381 gcacgcctgc tttcaggata tcctgaattt cagcagcaga aactgtcagt cccaatgctt
    13441 ttgcttcttt ctcaaccagt ttgttattaa cgt
//
