LOCUS       c00047_gnlPro..        16366 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFKOAHCJ_47.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:34:24
            Original ID  :: gnl|Prokka|NFKOAHCJ_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16366
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16366
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9808:13366](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9809..13366)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16366
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16366
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             149..1375
                     /locus_tag="ctg47_1"
                     /transl_table=11
                     /translation="MFFSLIVPLFLSLFYKPIAYLCGRSLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESDDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1708..4461
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.1e-20, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLTGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQCDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGRIAVRLSSLCKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             4489..4821
                     /locus_tag="ctg47_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4784..6070)
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLTLPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFHKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6544..7770
                     /locus_tag="ctg47_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKEEREKKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7767..8597
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg47_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8625..9485
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNAETIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPKKD"
     CDS             complement(9496..9684)
                     /locus_tag="ctg47_8"
                     /transl_table=11
                     /translation="MIGFVIWIVGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9809..13366)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13400..14605)
                     /locus_tag="ctg47_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14785..15939
                     /locus_tag="ctg47_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGAFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 ttcgtaaact tgggtaagat tttatagata ttgtttggag aggacttaga attcatcttc
       61 ttttctgttt cttatttcag taaatatccc ccttccctgt gttttgattt actacttaat
      121 ctgttaatta ttagaatgat aataacagat gttcttttct ctaattgtcc ccctctttct
      181 ttccttgttt tataagccga ttgcctatct ttgcggcagg tctttaaata ataaatcaaa
      241 aagagaaaac tactttatga aacacatttc aaacttcctc agatcaaaaa gctggaacgt
      301 atttttgttt ttatatcttg ctcttccttt gtttgcgcaa aaggaatata agatcgatca
      361 ggtatccgtt gtcaatgtag gcgatggcag actgttgttt caggaactga aaacggaaaa
      421 agcattgaat ggcgaacatc gcatcataga tggttatcat tccgcctatg tgctggcatc
      481 ttttaaagat ggtttctatg atggcggata caaagaatat gtagacaata tattaataac
      541 agaaggaagt tataaagaag gacggaagga tggtctcttc aagattaact ccaagtttga
      601 cggtaagctg aaagaagaaa agtcctataa ggaaggtaag ctggacggta cgagcaaaag
      661 ttactttact accggaaaag tggaaagtga aagaaacttc cggatgggga aagagcacgg
      721 gaagcaactg tcgtacgaat ctgacggtac tttgcggaaa gagcataatt acaaggacgg
      781 gaagcaggta ggcaaacagt atacttttct gaaaggtaca tatgatttgt atgagaccgt
      841 ttatttcaat gaagaaggtt ttcaggacgg tgaatattcg tccgtgttta cgtttggctc
      901 gccacgtata ctgggtagtt ataagaatgg aaagaagaat ggtcgttgga ctacttttgc
      961 tgaaagcgac gatacgctga tgattgaaac ctatctggat ggaaaagaag atggactcca
     1021 tgtctcattt gccaacggaa gtggggtaag gcagaaagaa tattatatga agaacgatcg
     1081 taaagacggt ttataccgtg aatataattt ggaaaatggt gaattgagat atgaagctac
     1141 ctatcaggcc ggcagattgc atggcaagga acgacggctg atagtgagca accgctttga
     1201 ttattgggaa acttctacct atgtgaacgg aaggcagaac ggaccgttcg aagctcgtta
     1261 tgtaaagaat gaccagcttc gtgaatgtgg ggaatataag aatggtcgcc gtgtaggacg
     1321 atggaaacgc tacactattg atggtaaact ggaaaaggaa tgggatgaaa actaaccggt
     1381 agatgaaagg tcagggcata aaaaaaggag caacgccttg ctccaacctt tgttaacctt
     1441 aaatctaata ctatgaaaaa cacagtacaa agatacggac ttctgtgaaa tctgcaaatt
     1501 atccaagtaa aacgctatgt tttataacat tgattaagtg tttgttttac gctttatact
     1561 tttgttaata ctttccgatg gtctgaaaga ggactgcttt ccttcttttt agaataataa
     1621 atagctgaag ttagagaact ttacagtatt atttcttatt tttgttctta attggattac
     1681 agaaagaact acgaaatgat gagatggatg aagacgatga gatatctgaa gtggatgctg
     1741 gtgctgtttt gtttaaccgg gatgacggct tgccggcagg atacaccccg ttttcgtatt
     1801 ggggtggctc aatgcagcga tgattcatgg cgacataaga tgaatgatga gattcttcgg
     1861 gaagcgatgt tttataatgg tgtttcggtg gaaatccgtt cggcagggga tgataacact
     1921 aagcaggcgg aagatgtcca ttattttatg gacgaaggag tcgatctgct gattatttcc
     1981 gctaacgaag ctgctcctat gactccgatt gtagaagaag cttatcagaa aggcatcccc
     2041 gttattcttg tagaccggaa gattctttcg gataaatata ctgcctatat cggagccgat
     2101 aattatgaaa tcggtcgttc ggtaggaaac tatattgcct ccagtctgaa agggaaggga
     2161 aatatagtag aactgacagg attgagcggt tcgactcctg caatggaacg gcatcaggga
     2221 tttatggctg ccatcagtaa attcccggat ataaagctga ttgataaagc ggatgctgct
     2281 tgggaacgtg gtccggcaga gatagaaatg gatagtatgc ttcggaggca tcctaagatt
     2341 gatgctgtgt atgcccataa tgatcgtatc gctccgggtg cctatcaggc agcaaagatg
     2401 gcagggcggg agaaggaaat gatttttgtc ggcatagatg ccttgccggg taagggaaac
     2461 gggctggagc tggttctgga cagtgtgctg gatgctacct ttatctatcc gaccaatggt
     2521 gataaggtac tgcaactggc tatggatatt ctggagaaga aaccctatcc caaagaaacg
     2581 gtgatgaata ccgctgttgt ggaccgtacc aacgcacacg tcatgcagtt gcagaccaca
     2641 cacatttccg aactcgacaa aaagattgaa acgctcaacg gacgtatcgg tggctatctc
     2701 tctcaggtag ctacacaaca ggtcgtttta tacggcagtc tgattatcct tttattggta
     2761 gccggcttat tattggtcgt ttataaatca ctccgctcaa agaatcgctt gaataaagaa
     2821 ctttttaagc agaagcaaca attggaagag caacgtgaca aactggaaga acagtgtgac
     2881 caattgatac aactttctca tcaactggaa gaagctactc atgccaagct ggtattcttc
     2941 accaatattt ctcacgactt ccgtactccg ttgacattgg ttgccgatcc ggtagaacat
     3001 ttgttggcgg acaagacact gagcggagat cagcaccgga tgctcatgct gattcagcgg
     3061 aatgtgaaca ttcttctgcg tctggtcaat cagattctgg atttccgtaa atatgaaaat
     3121 ggcaagatgg aatatactcc ggttacggtg gatgtccttt cttctttcga aggatggaat
     3181 gagtcttttc aggcggcagc ccgtaagaag catatccatt tttcttttga tagtatgccg
     3241 gatacggatt atcatacact ggcagacatg gagaagctgg aacgtattta tttcaatctc
     3301 ctgtccaatg cctttaagtt tacaccggaa aatggaagaa ttgccgttcg tctgtcttcc
     3361 ctttgtaaag aggacaagcg atggatacgt ttcacggtgg caaataccgg ttctatgatt
     3421 tctgccgaac atatccgcaa tgtattcgac cgtttctata agatcgatat gcaccatacc
     3481 ggttcgggaa tcggactggc attggtaaaa gccttcgtag aaatgcatgg tggtacgatc
     3541 tctgtagaga gcgatgagaa acagggtacg gtctttaccg ttgaactgcc tgtacagtct
     3601 tgcgaggctg ttgctgccga accggatacc acccttgttt ctgcggattc ccgtacaaca
     3661 gatgttctat tggcggaaga ggaagaactg gaaaaaggat atgactcttc caaatcgtcc
     3721 gtactgatta ttgatgataa tgaggatatc cgttcgtatg tccatacgct gttgcataca
     3781 gactatacgg tgattgaagc ggcagacggc tccgaaggaa tccgtaaggc tatgaagtat
     3841 gttcctgacc tgattatttc cgatgtgatg atgccgggca ttgatggcat tgaatgttgc
     3901 cgccggctga aaagtgagtt acagacctgt catattccgg ttattctgct gacggcgtgt
     3961 tcactggacg aacagcgtat tcagggatat gacggtggtg ccgattctta tatttcaaag
     4021 ccgttcagtt cacaactgtt gctggcacgt gtccgcaacc tgatcgattc tcaccgtcgt
     4081 ctgaaacagt tctttggtga cgggcagaca ttggcgaagg aagatgtttg cgatatggac
     4141 aaggattttg tagaaagatt caagtcattg attgaagaga aaatgggaga ctccggtttg
     4201 aatgtggagg acttgggcaa ggatatggga ctaagccgtg tgcagcttta ccgcaagatt
     4261 aaatcgttga ctaactactc tccgaatgaa ttgctccgta tcgcccgttt gaagaaggca
     4321 gcttctttgc ttgcttcttc ggacatgacc gtagcggaga ttggttatga agtcggtttc
     4381 agttcacctt cttatttcac caagtgctat aaagagcagt tcggagagag cccgacagac
     4441 ttcctgaaaa ggaaaggatg atttcattga gatcgtaaag agggatatat gaaagattat
     4501 aaagtagata aagagagttt ttccgaatcc tttcggaagg aagtgtacga agtcgtatcc
     4561 cagatacctg tgggaaaagt atctacctat ggaggtattg ctttgctttt gggtgccccc
     4621 caatgttcgc ggatggtggg gcgtgcattg aaagaagtgc cggatgaatt atccattcct
     4681 tgccatagag ttgtaaattc caccggaagg ctggtacccg gttgggtgga acaaaaacaa
     4741 ctcttgctgg cagaagaagt ttctttcaaa gctaacggat gcgttaatct gaaagaacat
     4801 ttgtggcacg tggatgaatg aaggatgcaa ggaaggtaag ccatatcatc cgtatccata
     4861 caataaagaa aacccataca tgaagccata aggtcctggt aatgaaatct ctgatgggaa
     4921 cagggacgaa tatgtcgata ggaacgatgc ataacagcac aaaacagcac caaaatagaa
     4981 tcttgtctgt tgcggtacgt gttggcctgc tccaatacca gagcatgaaa cctgccaatg
     5041 cgataatata ggtatgtttc tcggcggagt cactcagtaa tactacccag cccatgagaa
     5101 tgcccaaagc ttgggcacgg aaggcaaaag acgaccattt gtggaaattc cccaaaaaga
     5161 gcagagtcag tagaccgagc attcctatct gaagtgcacg gaagtgtggc aatgtccatg
     5221 ctgcaatggg gcgggcatag aaaaatgaat cataagctcc ggcggattga tgaacagcaa
     5281 gactatggca ccattcttca taatagggga gcaaatctgc aggagctatt ttgattaacg
     5341 gtaacgtaag caatacaatg cccattgcaa cggcatagcc aaagttacgc catacgtgag
     5401 gatagcacag caacaatgcc agttcgaaaa ttccatatac tttggtacat cccgaaatca
     5461 tgattaacag aacagccaga aatccacggt ctttttccaa taacgtatag gcgaataaga
     5521 ataaataggc taccgttatg ttatactgaa atgaaagtaa actttgtcct aaaatcagta
     5581 acagaaaaag gaacatacgg catttctgtt gctgggtgaa ttgttggggc agcgtgaaga
     5641 tcgccacaaa gaacaatgaa taattgaata gattccacgc gaaaggtccc agccatgcag
     5701 gcagatacgc aaacggagcg aacaataccg tgaaaacagg agaataaagg aagtagcgtc
     5761 cgtgagcttc tacaaattcg gttgtgtatg ggctgatgcc ttgccagaag aattgagtag
     5821 cgtctgagaa gaccataaag ttttgatgcc gtcctcgcat aaattcgagc agagtcacta
     5881 taaaagcgag caggaaacct atcatgtaga gattccgccg actatagaaa aacggcattt
     5941 tggggttctt tttactaagg aactgtactt ggcttttgtc gtctagtgtg gcagtacctg
     6001 tttgtttttc ttttgttgtg taatgacaat tatccttccc caggaaaatt gtaatagccc
     6061 tgttgaacat ataaatctag tttagttatt gacgccaaat atacggtgtt taggtgaaat
     6121 attcaaactt attttatatt tatctgctgg tttgttctat tttgctgagt gataggggaa
     6181 tattacccgg aaactttcca tatcattaca aataaagtcc tctgtatgcc ccggattttg
     6241 aatataattt gcatgtttaa tctgtttttt gtatctttgt gccagcaaga tactggaaca
     6301 gactgttttt atacataaaa atgctatttt tttgctattc gttgaaagga ttatcttatc
     6361 aaattctatt ccttttttaa ttactcagtc tgtcaataat cattttatta attatttcgg
     6421 gattcattgt tatttgtccc gtatttaaat cagaacttta tacgatataa agaaagattc
     6481 ctgttatcgt ttgttcttgt cttgctgtgt atattatttt aataacctaa accattttat
     6541 tgtatgagta aaatagaaat taaagatctc tatctggttt ttggcaatga gaagcagaag
     6601 gctttgaaga tgttgaaaga aggtaaaact aaaagtgaaa tattgaaagc gaccggatgt
     6661 acggttgcgg tgaaagatgc gaatctttcc attaatgaag gcgaaatatt cgtcattatg
     6721 gggttgtccg gtagtggaaa gtccacttta ctccgctgca tcaaccgttt gatacgccct
     6781 acttccggag aagtgattat caatggaaca gacatagcca aagtgtcgga taaagaactg
     6841 ttgcagattc gccggaaaga actggctatg gtctttcaga acttcggtct gcttcctcac
     6901 cgttctgtct tgcataatat agctttcgga ctcgaactac agggagttaa aaaggaagaa
     6961 cgggagaaga aagcgatgga aagtatgcaa ctggtggggc tgaaaggcta cgagaatcag
     7021 atggtaagtg aactgtcggg tgggatgcag cagcgtgtcg ggctggcgcg ggctttggcc
     7081 aataatcccg aagtcctgtt gatggatgag gccttctcgg cactcgatcc tttgatccgt
     7141 gtgcagatgc aggatgaact gctgactttg cagtcgaaga tgaaaaaaac gattgtcttt
     7201 attactcacg acctgagtga agcgattaaa ttgggtgacc ggattgctat catgaaggat
     7261 ggagaaattg tacaaatcgg tacatcggaa gaaatcctga ccgaacctgc caacgcttat
     7321 gtagaacgat ttgtggagaa tgtagatcga agcaagatta taacagcttc ctctgttatg
     7381 gtagataaac ccatagtggc acgtttgaag aaagaaggcc cggaggtgct gatccgtaag
     7441 atgcgcgaac ggaatctgac cgttcttccg gtagtcgatt ccaataatct gttagtagga
     7501 gaggtgcggt tgaatgactt gctgaaacta cgaaaagagc aaatccgctc catcgagtcc
     7561 gtagtaaggc atgaagttca ttcagtgctg ggtgatacgg tgctggaaga tattcttccg
     7621 ttgatgacaa aaacgaactc gccaatctgg gtcgtaaatg agaatcggga gtttgaaggc
     7681 gtagtgccac tttcctcatt gatcatcgaa gtaacgggaa aagataaaga agaaattaat
     7741 gaaatcattc aaaacgcaat agaattatga taaatatcgg acaatatata gaaactgcca
     7801 ttaattggct cacagaacat tttgcttcct tttttgatgc tctcagcatg gggatcggag
     7861 gattcataga cggttttcag cacgtactgt ttggaatacc tttttatatc acaattgcag
     7921 tgctggctgc gctcgcctgg tttaagtcgg gtaaggggac agccgtattt accctcttgg
     7981 gcttattgct tatttacggc atgggctttt gggaagaaac gatgcagaca ttggcgttag
     8041 tactttcttc cacttgtctg gcattgcttt taggcgttcc gctgggaatc tggactgcca
     8101 acagtgatcg ttgtaacaag ataatgcgcc ctgtcctcga ctttatgcag acaatgcctg
     8161 cctttgtcta tctgattcct gccgttctat tcttcggatt gggaactgtg ccgggagctt
     8221 ttgccaccat catctttgca atgcctcctg tggttcgtct gaccggcctg ggcattcgtc
     8281 aggttcctaa aaacgtagta gaagcctccc gctcttttgg agctactccc tggcagcttc
     8341 tttataaggt acaattgcct ttggcgttgc ctactattct gacgggaatc aaccagacga
     8401 tcatgatgtc actttcgatg gtagtgattg ccgccatgat ttctgccgga ggattgggag
     8461 aaatcgtgct gaaaggtatc acccaaatga aaatcggact cggatttgaa ggcggtatcg
     8521 cagtcgtgat attggcgatc gtgctggacc gcatcactca gggcatggca gataacagaa
     8581 aaagtaaaaa gaaataagaa tcacaccaaa gaaaggaata atcaatgaat aagataaaaa
     8641 tgattgcggc aatgtttatt gccggcatac tcttaacctt cgtttcctgc ggagacaacg
     8701 gaaagagtaa gaagataagt atcgcttatg ccaactggtc ggaagggatt gccatgacaa
     8761 accttgccaa agcgattttt gaagatcagg gatacgatgt aaagttgctg aatgccgacc
     8821 ttgcacctat atttacctct atctcccgta agaaagcaga cgtatttatg gatgtctgga
     8881 tgcctgtcac tatggaagat tatatgaaac aatacgggga taaactcgaa gttatcgggg
     8941 atatttatga tggtgcccgt atcgggctgg tggttccgga ttacgttacg atcaactcga
     9001 tcgaagaact gaacgcggaa aaggaacgtt tctccggtca gattgtcggt attgatgccg
     9061 gagccggtat tatgaaagct accgatcagg ccatcaaaga ctatggattg gattataaac
     9121 tgatgacttc gagcggacct gccatgactg cttccctaaa gaaagcgatt gataagaaag
     9181 actggattgt cgtgacggga tggacgcctc actggatgtt cgaccgtttc aaactgaaag
     9241 ttcttcagga cccgaagctg atatatggaa atgcggaaac cattcatacc atagcgtgga
     9301 aaggttttag cgagaaagat ccttttgctg ccgaacttct gggcaatatt cgtctgactg
     9361 atgcggaaat cagctcttta atgactgctc tggaagaggc gcagacgacg gaaagacagg
     9421 ctgcccgtca atggatggaa gaacatcagg aactggtaaa cagttggatt cctaagaaag
     9481 attgataagc aaacactact tcaaccatcc cgccattctt tctttaccat agaagtagta
     9541 gaaaagtagt cccagccagc tggtaagaac gattaataca atcgctataa gccttttctc
     9601 tacagccgca tttatattcc aaatctctat ggcagctctg aaagtcagta tcaaaccgac
     9661 aatccaaata acaaatccga tcatatcttt agagttttaa tgaatatctt cgtgagaagt
     9721 aatcgttact tctaatatat aaacaaaaaa ggcaggaatc tgtttccagg attcctgcct
     9781 tttattatgt acaaagtatt tctacttatt attcagctgt atcagctccc cagttttctc
     9841 tggcaagacg tttgtagctg ttgtaacgcc atttagcgtt ttcttcagca gctttaaaca
     9901 gttcttcagc ttcagcaggg tattgtttca ttacagaagc gtaacgaact tcacccttca
     9961 agaaaccttg gaagtcttcc cagttaggtt ctttgctatc cagctggaac ggattcttgc
    10021 cttcttcttc caaagcaggg ttgtaacgcc acaagtgcca gtaaccgcac ttaacagcct
    10081 tttcttcttc ttcctggctc ttacccatac cggctttcag accgtggttg atacatggag
    10141 cgtaagcgat gatcagtgat ggtcccggat atgcttcagc ttcgcggatg gctttcagag
    10201 tctgagcctg gtcagcaccc atagcaatct gagcaacata tacataaccg taagtagtag
    10261 ccatcagacc gaggtctttc ttacgtacac gcttacctgc agcagcaaac ttagcgatag
    10321 cgcctaccgg agtagcttta gaagactgac cacctgtgtt agagtaaacc tcagtatcca
    10381 atacaaggat gttaacgtcc ttaccggaag cgattacatg gtcaagacca ccgtaaccga
    10441 tatcgtaaga agcaccgtca ccaccgatga tccattggct acgtttaaca agatattgtt
    10501 gcagatcagc gatttgcttg cagtggttgc atttatcttt agcagcttct accatcggaa
    10561 tgatcttttc agccagttcc ttagtctttt ctgcatccag catattgttg atccattcag
    10621 cgaatacttc tttgtattca gctgggcagc aatcagaagc gatagcttcg ttcattactt
    10681 tcaccagacg ggcacgcatt ttttcgttag ccagttccat acccagacca aattcacaga
    10741 agtcttcgaa caaggagtta gcccatgcag gaccgtgacc cttttcgttc atagtgtacg
    10801 gagtagaagg aactgaacct gagtagatag aagaacatcc tgtagcgtta gcaaccattt
    10861 cacggtcacc gaacaactga gaaatcagtt tcacgtacgg agtttcacca caaccggagc
    10921 aagcgcctga gaactcaaac aacggagttg cgaactgaga gttcttcacg ttagccttga
    10981 tgtctaccag gtgttgtttg ctcttcacgt tttcagcgca gtaagtccag ttatcagctt
    11041 cggccaactg gctttcaagg tgtttcatgg tcaatgcctt gccacccttc ttcggattac
    11101 ccggacagat gtcggcacag ttaccgcaac ccagacagtc gagaacgtct acctgaatac
    11161 ggaatgtcat accatcgaat gctttaccta cagctttcag ttgctcgaac ttagcaccct
    11221 tctgctcttc agcatcgagt acgaacggac ggatagaagc gtgaggacaa acgtaagcac
    11281 acttgttaca ctgaatacag ttttcagcat tccattcggg aacgaatgca gctacaccac
    11341 gtttttcgta tttggaagta ccttgatacc aagtaccgtc ttcgataccc ttgaatgcag
    11401 ataccggcag caagtcaccg tcctgtgcat tgatcggacg aactacttcg ttgatgaaag
    11461 caggatcatt gttttctgct tttgcatcat ccggcaggtt agcccaagca ggatcgacag
    11521 tcagagtctt gtattcacca ccgcggtcta cagcagcgta gttcttgtta acaacgtctt
    11581 cacccttctt gccgtaagac ttaacgatga atttcttcat ctgttcaaca gcttgatcta
    11641 caggaataac gcctgtgata cggaagaatg cagactgaag gattgtattg gtacggttgc
    11701 ccagaccaat ttccattgca atctgagttg cgttgatata gtatacagag atgttgttct
    11761 gtgcaaagta tttcttcacc ttgttaggca ggttcttagc cagttcttcg ccttcccaga
    11821 tggtgttcag caagaaagaa ccgttcttac gcaaaccacg tgttacatcg tacatgtgca
    11881 ggtaagcctg aacgtgacaa gcaacgaagt tcggagtatt taccaagtaa gtagaacgga
    11941 tcggagtatc accgaaacgc aggtgagaac aagtgaaacc acccgacttc ttggagtcgt
    12001 aagagaagta agcctgacag tgtttgtcgg tgttgtcacc gataatctta acagagttct
    12061 tgttggcacc tactgtaccg tcagcaccca gaccgtagaa tttagcttcg aacatacctt
    12121 cgccgcccaa agcgatttct tctttctgag ggagagaagt gaacgtaacg tcgtctacga
    12181 taccgatagt gaagtggttc ttcggcattg gcatagccaa gttttcgaat acagagatga
    12241 tctgtgccgg agtggtatct tttgaaccca gaccgtagcg accgccaacg ataacaggag
    12301 cattttctgc gccatagaag cagtctttaa cgtcaaggta aagaggttcg ccgttagcac
    12361 ccggttcttt tgtacggtca agcactgcga tgctctttgc agtcttgggt acagcagcca
    12421 ggaagtgttt agcagagaac ggacgataca agtgtacggc aaccatacct actttttcgc
    12481 cgtttgctac caagtggtcg atagcttcgc gggcagcttc agttacagaa cccattgcga
    12541 taattacgcg ttctgcatct tctgcaccgt agtaatcgaa caaaccgtat ttgcggcctg
    12601 tgatcttgga aatttcgttc atgtattctt ctacgatagc aggaactgct tcatagtagt
    12661 tattgcatga ttcacgatgt tggaagaagt ggtcggggtt ttcagccata ccacgggcaa
    12721 ccggcttcat cggattcagt gcacgggcac ggaattcagc caaagcttcc tggtcgatca
    12781 gcggagcgag gtcgtcgttt tccaacattt cgatcttctg gatttcgtga gaagtacgga
    12841 aaccatcgaa gaagttcatg aacggaacgc gtgatttgat agtagccaga tgagcaacac
    12901 ctgccaaatc cataacttcc tgtacagaac cttctgccaa catagcgaag ccggtttgac
    12961 gagctgacat tacgtcctga tggtcaccga agatacacaa tgcgtgagaa gccagtgtac
    13021 gagcagaaac gtggaataca caaggcaaga attcaccggc aatcttgtac atgttaggga
    13081 tcatcaaaag aagaccctga gaagcagtgt aagtagtagt caatgcacca gcctgaagag
    13141 aaccgtgaac tgcaccggca gcaccacctt cagattgcat ttcctgtacc aatactgttt
    13201 cgccgaagat gttcttacgt cctgcggcag cccattcgtc tacgtactca gccatagtcg
    13261 aagaaggagt gatggggtag atagctgcta cttcagagaa catatacgag atatgtgctg
    13321 cagcttggtt accgtcacat gtgatgaatt tcttctgttt agtcataact aaattaaata
    13381 tttaagtaaa taaatctttt tagtataaga atccgaacat ccaaagaggt atttggttgc
    13441 cgcggcctat ctcagccttt tgcaacgcat acgtcacgtc cgggttattc tttatttttg
    13501 taccttccgc acaaattttg aacggcatca cttcgtctac catgaaagag acgtttttat
    13561 ctcctttatg taccttatgg tctttccata aagtgttaac gaagaacgtg tcgagtacat
    13621 cctgttcttc cactttcacc ggataaatgg agtacatcag gttagagttg tgcatcataa
    13681 tctttgacgg tttctttggg aattcttctc ctttcgggta aaccagatta atcagacgcg
    13741 cgtctgccag atacttgata tagttcatta ccgtagcgcg ggatgtctgt acgtcacttg
    13801 ccagttggct cacgttcgga gctttcggtc cgtccacagc caacaaatat agtaattttt
    13861 ttatctttga aagatatttc agctcaattt gtttgatcag caagatatcc acttctacca
    13921 tcatgttcat tgttttcagc agattctccg agaaattacg tttttcaagg aagaaagggt
    13981 agaaaccatg atgcaggtaa tcctgaaaat aatccagcgg tcgtactttg gaaagtactc
    14041 ctttggctat ctgttcatgt gtactgagga tttcttcgag gctgtatgcc cggaatttca
    14101 ttcctgtctg caggttcaga aattcacgga aagagaatcc gcgcaggtta taacttttcg
    14161 caatgtcacg caattcgagg ttttcctctt tgagtcgcat gacggaagaa ccggtgaaga
    14221 caatcttcag gctggggaaa cggtcatagc acattcgtag ctctttgctc cattcgggat
    14281 gtttgaacac ctggtcgatc agcagtactt ttccgccacg tttctgaaac tcgttggcga
    14341 agtcaacaag gctgtgaccg gagaaataaa agttgttcat attgatgaac agacaggaac
    14401 ggtcggtgcc gaatttctct ttggcgtact gcaggaggaa agtggttttt cctacgccac
    14461 gtgtcccttt gataccaatc agacggtcac tccagtcgat ctcgtccata agatcgcggc
    14521 gaacgggggc attggtgtgc tcaacgaggt aggcgtgtgt gcgatagaat gattccattt
    14581 cgtttctttg tttttcggct ggcaaatata gtgctttttt taggatttgc aaagtagaga
    14641 tagcaaaaat gtgctttaat ttataagttt ctctttattg tgtaagttcc tgattatttc
    14701 ctgtatatat ttgcagaata atgtgttgaa tccatctttg acatgacgaa aagacctgtt
    14761 tatatattca atccggagca tgatatggcg ttggcaagcg gtgagacgaa ctatatggcg
    14821 ccggcttccg cccgacagat ggcgagtgac ctggcgttgc ttcctatgtg gtatgccgaa
    14881 gcgggaagtg cggtgcttgc accgtctgct tataatgcgg acttcctgaa aacaaagagt
    14941 gaacttttgg gcatggatgt ggccttgttg acggaaccgg aagtggctga cggtaaagac
    15001 cggaagttct ctccgtgggg gtgggaccct gctttgcgga agcgtttgat gacattgggg
    15061 gcagatcaga cggagctgcc ttctgcggat tatatgaata ttctgagaga gcattcgcat
    15121 cgtctgcagg cggtaaagtt gttgcctggg ttgcggttga atgaatactt ctgtggagaa
    15181 tctttttatt tgagtacttt ggcggagtgc agtgcgttcg tcgaagggcg ggaagcgtgc
    15241 ttgttaaaag ctccgctttc cggaagcggg aaaggattga attggtgtaa aggcatattt
    15301 actactttta tttccggttg gtgtgcccgt gtcgctgctt ctcagggtgg ggtggtaggc
    15361 gaacctatat ataataaggt ggaagatttc gctatggagt tttatgctga cgggagagga
    15421 agggttgttt ttgccggata ttcggtcttc cacacgggtg ggagtgggat gtatgcaggg
    15481 aatgacttgc tgtctgacga gaagattctg cagaaactat cggcttatgt gccacaagaa
    15541 gaatttatca ggctgcggac tcgtttggaa gaagaattgt cagctttgtt cggtggcttt
    15601 tatcatggat acttgggagt ggatatgatg atttgtcatt ttccggatga agcgcctgtt
    15661 taccggattc atccttgtgt cgaaattaat ctgcgaatga atatgggggt ggtggcatgg
    15721 ctcttgacgg atcgttattt ggctgcggat gcggaaggag cttttcggat tgattattat
    15781 cctttagccg gtcaggcttt ggaggaacat cggcagatgt cggcttcgtt ccctttgtcc
    15841 gtagagaata atcgggtgtg tgccggatat ttgccgttag taccggtgac gcctcaaagc
    15901 cggtatcgtg cgtttctttt gcttactctc ccccagtgaa aaagatagtg cttttgctct
    15961 catgctctaa cagttcgtct gtatcccttt attcatcgat gttttagctg ttagagatcc
    16021 agtggtagca gagtgagagc aaggacttgc tctcactctg catcgtcctg ataaataccg
    16081 tttttactgt gttattcttt gatttacagg atgttaatat ctgatatctc aactgttaac
    16141 gtttgatttc tcagatatta ataattgaga aatcaagtat taaggactga taatttatgt
    16201 attattgact gatatatgat ttaatgtttt cagagagagc agtactattg aagtagctga
    16261 tgcgttcaat gtgattggaa catgcggtta agtcaatcaa atcaacagta gttgtcttac
    16321 cctggatttg gttgactact ataagtatca actaaaatga ataaaa
//
