GCA_034130865.1 - 11 region(s)

Identified primary metabolite regions

c00003_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_3)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 3.1	TPP_AA_metabolism	Putative	247,807	273,794
Region 3.2	succinate2propionate	SCFA	310,100	334,743	Succinate to propionate B. theta	PRO	50%

c00017_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_17)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 17.1	fatty_acids-unassigned	Putative	211,467	239,935

c00018_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_18)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 18.1	porA	SCFA	73,452	96,289	porA C. sporogenes	POR	60%

c00028_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_28)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 28.1	Rnf_complex	E-MGC	272,143	297,479	Rnf complex C. sporogenes	RNF	83%

c00034_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_34)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 34.1	Fumarate2succinate	SCFA	17,426	40,881	Fumarate to succinate B. thetaiotaomicron	SUC	100%

c00038_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_38)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 38.1	NADH_dehydrogenase_I	E-MGC	198,151	228,020	NADH dehydrogenase I Bacteroides sp.	NADHD	66%

c00039_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_39)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 39.1	TPP_fatty_acids	Putative	1,731	25,798

c00040_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_40)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 40.1	Fumarate2succinate	SCFA	17,417	40,872	Fumarate to succinate B. thetaiotaomicron	SUC	100%

c00042_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_42)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 42.1	Pyruvate2acetate-formate	SCFA	142,142	165,167	Pyruvate to acetate-formate B. thetaiotaomicron	PFL_acetate	100%

c00047_gnlPro.. (original name was: gnl|Prokka|IFBOFGCH_47)

Region	Type	Class	From	To	Most similar known cluster		Similarity
Region 47.1	PFOR_II_pathway	SCFA	52,137	75,682	PFOR II pathway B. thetaiotaomicron	PFORII	100%

Region	Type	Class	From	To	Most similar known cluster	Similarity
Region 3.1	TPP_AA_metabolism	Putative	247,807	273,794
Region 3.2	succinate2propionate	SCFA	310,100	334,743	Succinate to propionate B. theta	PRO	50%
Region 17.1	fatty_acids-unassigned	Putative	211,467	239,935
Region 18.1	porA	SCFA	73,452	96,289	porA C. sporogenes	POR	60%
Region 28.1	Rnf_complex	E-MGC	272,143	297,479	Rnf complex C. sporogenes	RNF	83%
Region 34.1	Fumarate2succinate	SCFA	17,426	40,881	Fumarate to succinate B. thetaiotaomicron	SUC	100%
Region 38.1	NADH_dehydrogenase_I	E-MGC	198,151	228,020	NADH dehydrogenase I Bacteroides sp.	NADHD	66%
Region 39.1	TPP_fatty_acids	Putative	1,731	25,798
Region 40.1	Fumarate2succinate	SCFA	17,417	40,872	Fumarate to succinate B. thetaiotaomicron	SUC	100%
Region 42.1	Pyruvate2acetate-formate	SCFA	142,142	165,167	Pyruvate to acetate-formate B. thetaiotaomicron	PFL_acetate	100%
Region 47.1	PFOR_II_pathway	SCFA	52,137	75,682	PFOR II pathway B. thetaiotaomicron	PFORII	100%

Compact view

c00003_gnlPro.. - Region 1 - TPP_AA_metabolism

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Location: 247,807 - 273,794 nt. (total: 25,988 nt) Show pHMM detection rules used

TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

resistance genes

encapsulation genes

electron transport genes

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c00003_gnlPro.. - Region 2 - succinate2propionate

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Location: 310,100 - 334,743 nt. (total: 24,644 nt) Show pHMM detection rules used

succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

resistance genes

encapsulation genes

electron transport genes

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c00017_gnlPro.. - Region 1 - fatty_acids-unassigned

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Location: 211,467 - 239,935 nt. (total: 28,469 nt) Show pHMM detection rules used

fatty_acids-unassigned: (not (EC1_2-faecali or baiH or baiCD or ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2, HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N, ketoacyl-synt]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

resistance genes

encapsulation genes

electron transport genes

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c00018_gnlPro.. - Region 1 - porA

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Location: 73,452 - 96,289 nt. (total: 22,838 nt) Show pHMM detection rules used

porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

Legend:

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transport-related genes

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resistance genes

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c00028_gnlPro.. - Region 1 - Rnf_complex

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Location: 272,143 - 297,479 nt. (total: 25,337 nt) Show pHMM detection rules used

Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

Legend:

core biosynthetic genes

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transport-related genes

regulatory genes

resistance genes

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c00034_gnlPro.. - Region 1 - Fumarate2succinate

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Location: 17,426 - 40,881 nt. (total: 23,456 nt) Show pHMM detection rules used

Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

Legend:

core biosynthetic genes

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regulatory genes

resistance genes

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c00038_gnlPro.. - Region 1 - NADH_dehydrogenase_I

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Location: 198,151 - 228,020 nt. (total: 29,870 nt) Show pHMM detection rules used

NADH_dehydrogenase_I: (Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))

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c00039_gnlPro.. - Region 1 - TPP_fatty_acids

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Location: 1,731 - 25,798 nt. (total: 24,068 nt) Show pHMM detection rules used

TPP_fatty_acids: (TPP_enzyme_C and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and not (POR or POR_N))

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regulatory genes

resistance genes

encapsulation genes

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c00040_gnlPro.. - Region 1 - Fumarate2succinate

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Location: 17,417 - 40,872 nt. (total: 23,456 nt) Show pHMM detection rules used

Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

resistance genes

encapsulation genes

electron transport genes

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c00042_gnlPro.. - Region 1 - Pyruvate2acetate-formate

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Location: 142,142 - 165,167 nt. (total: 23,026 nt) Show pHMM detection rules used

Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

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c00047_gnlPro.. - Region 1 - PFOR_II_pathway

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Location: 52,137 - 75,682 nt. (total: 23,546 nt) Show pHMM detection rules used

PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

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