LOCUS       gnlProkkaAEPLFIFD_550  11447 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEPLFIFD_550.
ACCESSION   gnlProkkaAEPLFIFD_550
VERSION     gnlProkkaAEPLFIFD_550
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:59:32
            Original ID  :: gnl|Prokka|AEPLFIFD_550
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11447
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11447
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2133:6447]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2134..6447
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11447
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11447
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..911
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 34.4;
                     E-value: 1.6e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg550_1"
                     /transl_table=11
                     /translation="MTLEDLIIQAGGLKEAASTVRIDISRRIKNPRSTADNDTIGQMYT
                     FSLKDGFVIDGQPGFILEPYDQVYVRRSPGYQAQQNVAIEGEILFGGNYAMTSREERLS
                     DLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLGEAMIDSLGIRVEDTF
                     TVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMVPNTVSYMKGKNVDYY
                     LNQAGGYSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPSKAKKKGNIANILG
                     YATSFSSLGMMIASIANLIKK"
     CDS             922..2070
                     /locus_tag="ctg550_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             2134..2853
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg550_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.4e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2874..4175
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg550_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.9e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.4e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             4192..5316
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg550_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5326..6447
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg550_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg550_6"
                     /sec_met_domain="Aminotran_5 (E-value: 2.3e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5416..6423
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg550_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg550_6_Aminotran_5.1"
                     /locus_tag="ctg550_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6444..6587
                     /locus_tag="ctg550_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6790..8274
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg550_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8228..9487
                     /locus_tag="ctg550_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9496..10245
                     /locus_tag="ctg550_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             10245..11285
                     /locus_tag="ctg550_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 acatgacact tgaggatctg atcattcagg ccggtggctt gaaagaagcc gcctctactg
       61 tccgtattga tatatcgaga cgaatcaaga atcctcgtag tactgcggat aatgatacga
      121 ttggtcagat gtataccttc tctttaaagg atggttttgt aatagatggt cagcccggtt
      181 ttatccttga gccttatgat caggtttatg tccgtcgcag tccgggctat caggcacaac
      241 agaatgtagc cattgaaggt gaaatccttt tcggaggaaa ttacgccatg accagccgtg
      301 aggaacgtct ttccgattta gtgaataaag ccggcggtcc gaccaattat gcctatctgc
      361 gtggtgcgaa actgacccgt gtggctaacg ctagtgaaaa gaaacgtatg ggtgatgtaa
      421 ttcgccttat gagcaggcaa ttgggcgaag ccatgattga ctctttgggt attcgtgttg
      481 aagatacttt tacggttgga atagatttgg aaaaagcctt gagcaatcct aaaagtaatg
      541 ccgatcttgt cttacgtgaa ggtgatgtga tctccatacc taagaatact aatactgtaa
      601 ctatcaatgg tgctgtcatg gttccgaata cggtttctta tatgaaggga aagaatgtgg
      661 attattacct gaatcaggcc ggtggttatt ctgataatgc aaggaagagt aagaaattca
      721 ttgtttacat gaatggtcag gtgacgaagg ttaagggtag tggtaagaaa cagattgagc
      781 cgggatgtga gattattgtg cctagtaagg ctaagaagaa agggaacata gctaatattt
      841 taggttatgc tacttccttc agttctttgg gaatgatgat tgcttctatt gctaatttga
      901 taaagaaata aatgacctat tatgattgaa aagcaatctt atcaagaacc gttttctgaa
      961 gtggataaaa ggaaagatga tgaaatggaa atagacttga tggctatttt ttataagatt
     1021 attactgttc gtggagtact atgcaaagct gctggagtgg gagtaataat tgctatagtg
     1081 gtggcattga gcattcccaa gcaatataca gtaaaggtta ccctttctcc tgaaatgggt
     1141 aatgcgaagg gaagtaatgg tttagccgga cttgctgcct cgtttttggg agatggggct
     1201 ctaatagggg aaagcacaga tgccttgaac gcttctcttt cagcagatat tgtttcttca
     1261 actccttttt tattggaact tttagaaatg gaagtctccg tttctaaaaa ggatgataaa
     1321 atgactttgg ggtcttatct cgatgaagag tcatctcctt ggtgggatta tcttataggt
     1381 tttccgggca tagtaatagg aggagttaaa tcattattcg gagaagatac ggttcctgcc
     1441 agtggagggc ggcaaggaac tatcgaattg acgaaagaag taaatgagaa gattaatttt
     1501 cttaaaaaga agattagtgc atccattgat aagaaaaccg ccataacgag cattacggtc
     1561 accttacaaa atccgcagat cactgcggtt atagcagatt ctgtcgttca taaattacag
     1621 gaatatatta ttgggtatcg aacttcaaaa gtaaaagaag actgtgcgta tttggaacgg
     1681 ttgtttaaag aacgtcagca ggaatattat gctgctcaaa gaaaatatgc ggattatgta
     1741 gacgcccatg ataatgtggt tcttcaaagt gtacgtgctg agcaggagcg tttacagaac
     1801 gacatgagtt tggcttatca gatatatagt caggttgcta atcagttgca ggtatccaga
     1861 gccaaagtac aggaggaaaa gccagtcttt gcagtagttg agcctgccgt tgtacctttg
     1921 aaaccttcag gtatgggact caaaatttat attttattat ttgtgttcct gtccgtatct
     1981 ggtactctcg tgtgggtgtt ttttggcaaa agtctgctgg ctagcttgag aaaagaactg
     2041 aaaaataagg agatagaaca ggataaatga tgctaaaacg tcgtttacaa cattcttaca
     2101 tcaattaaat tcacttacta tattattaaa cgaatgatac gtacagctat gataatggct
     2161 gcgggcatgg gaacccgttt tggccaatat acagaattga tacctaaagg gttcgtcaaa
     2221 gtgggaggta ttccaatgat agttcgttct attgatactt tgttatcatg tgacattgag
     2281 cgaattgtaa tcggtacagg atataaacaa gaagtttatg aagaattgaa gacagactat
     2341 cctatgcttg aaacctgttt tagtcctcgt tatgctgaaa caaatagtat gtatacttta
     2401 tataatacgc gggagattct gggcaatgat gattttttat tgttagagtc agatttgatt
     2461 tttgagaaac aagcaataat gagcttattg gagtgtcctg cggcagatgc aatgctaata
     2521 actccagtga caaagtttca agatcagtat tatgtggaac atgatgataa ttttcgcctt
     2581 tcttcatgtt ctgtcaataa gaataaacta aacgctaaag gcgaattggt cggcatccat
     2641 aaactatccg gttcctttta caaaataatg tgtgctgatt atgcgagtat tgttgatgaa
     2701 caacccaatt tgggatatga gtatgaatta ctacgaatat cttgttctca atctcctgtt
     2761 tatgtgcata aagtagaagg gctgaaatgg tatgaaatcg atgacatatc agatttggaa
     2821 tatgcagaga aatatattgt tccgtattgt taattaaaat aatatatcaa attatgagta
     2881 agacagttta tattgggatg actgcggata ttatgcatcc aggacttatc cgcattatta
     2941 atgaggctac taaatacggt gatgttataa ttggtcttct tacagataaa gctattgcgg
     3001 agcataaacg ccttccttat ctgacctatg aacaacgaaa agaggtagtt cagaatatta
     3061 aaggcgtatg taaagttgtt cctcaagaag aatggagcta tgttgagaat ctcaaacgca
     3121 ttaaacctga ctatataatt catggtgacg actggaaaac cgggccttta cgtgaagaac
     3181 gtgtgcgcgt atttgaagtg atgaatgaac agggaggaaa ggttatcgaa attccatata
     3241 ctttgggaat taattcatct tctttggata aagatattaa ggctataggt acaacccctg
     3301 atgtacgttt aaaatcactt cgtcgtttga taaatgccaa acccgtagtt cgtattttgg
     3361 aagctcatga tggactatgt ggcttgataa ttgaaaatca ggaaatatta aaaggggata
     3421 agagggaagt atttgacgga atgtggtcta gtagccttac ggattcaacc agtaaaggta
     3481 aacctgatat tgaggcggtt gatttaacta cccgattgca agatttgaat aatattctgg
     3541 agtgtactac taaacctatt atttttgatg gagatacagg tggtaaaatt gaacatttcg
     3601 tatttacagt acgcacttta gaacgtcatg gaatttcagc tataataatt gaagataaag
     3661 ttggattaaa aaagaattca ttgtttggta cagatgttat tcaaactcaa gatacaatcg
     3721 aaggtttctg taataagatc aaagcaggaa aggcatctca gattactgat gattttatga
     3781 ttatcgctcg tattgagagc cttatagcgg gaaagccggt aagtgatgct ttagagagag
     3841 cttttgcata tgtccaagcg ggagcggacg gtattatgat acatagcaaa aataagtcgg
     3901 gtgaagatat aaaagaattt tgtttggcgt ttcgaaaaca gtatgctcat gtacctatcg
     3961 tggttgtgcc tactacatat gatcatattt atgagtctga attgtgtgat tggggtgtga
     4021 atataattat ttatgctaat catatgcttc gtgccgctta tcctgctatg atgaatgtcg
     4081 caaagataat attagagaat gaacgtgctt tagaggtgcg cgaactgtgt atgcccataa
     4141 aagaaatatt ggaactgatt ccaggtacta aataaaaaga ggaatatcat tatgttaagc
     4201 gtagaaaaag tttatgaaac gtttctgagt catgacgttg atttttttac aggagttcca
     4261 gactcattac taaaaaatat ttgtgcctat atcacagacc atacttcacg tgagaaacat
     4321 atcatagctg ctaatgaagg tgcggctgta ggaattgctt caggttatta tatggcatca
     4381 ggtaaggttc ctgtggttta tatgcaaaat tccggcttgg gtaatactgt taatcctctg
     4441 ctgtctcttg cagatgaaca agtatacagt tttccaatgc ttttgatgat tggctggcgt
     4501 ggtgaaccgg gaacaaaaga tgaacctcag cataaaaaac agggtgaggt aactttagat
     4561 ttgttgaaag caatgcggat tccttatata attcttgatt caaatgagaa tgatgcattt
     4621 attcagctcc atgatatcat acaatcagca aaaactaaga atattcctca tgcaataatt
     4681 attcggaaag atgtttttgg caaatataaa cttcaaaaag agttcggatg taattatcct
     4741 ttatctcgtg aggatgcttt gcaaatagtt gtggattatc tgcctgaaaa ttcagtggtc
     4801 gtttctacta ctggcaagct ttctcgtgag ttatttgaat atcgagaaat gaaagagcaa
     4861 ggtcatgaac atgattttct cacggtaggc tctatgggac atagttcatc aatctctttg
     4921 ggtattgcta tagcaaagca agatagacct gtttattgct tggatggtga tggagcattt
     4981 attatgcatt taggggcaat tagtaacatt ggcgatttat ctcctaaaaa ctattatcat
     5041 attttgttta acaatggtgc tcacgagtct gtaggaggac agcctacttt aggatttagt
     5101 ttagatattc cggctattgt ccgggggagc ggatataagc atacttatac tgtttgtaca
     5161 aaagttgaaa ttgaagaagc aatgaagcag cttccaaagt tatgtggtcc tgttttgttg
     5221 gaaataaagg ttaaaataga ttctcgggag aatttgggac gtcccacgac tactcctata
     5281 gagaataagg agcattttat ggatttttta aaataaatat attcgatgaa aatagaaaga
     5341 aaaatattat taaatcctgg gcctgccact actactgaca gtgtaaaaat ggcacaagtt
     5401 gttccggata tttgtcctcg cgagaaagaa ttcgcaggta tgatgaaaca acttcgggac
     5461 gatttggtca gagttgctca tgggaatttg gaaaaacata ccgctgtatt attttgtggc
     5521 tcaggaacca tcaatattga tatatgtcta aattctcttc ttcctgaaga caaaagggtg
     5581 cttatagtga ataatggggc atatagtacc cgtgctgtag aagtgtgtca atattatggt
     5641 ttgcctcata ttaatttgga attttccgtt tacgaacgtc ctgatttatc ggtggtggaa
     5701 aatgtgttgc aagaaaatcc tgatatagct atggtttata ctactcatca cgagacgggt
     5761 acaggaattc tgaaccctat tcgcgagatg ggcgctatag ctcataaata tcaggctaaa
     5821 tttgtcgtcg atactacttc ttctttgggc atgattcctt ttgatataga gaaagataat
     5881 gtggattttt gtatggcatc tgctcaaaaa ggacttcaag cgatgacagg tctttctttt
     5941 attataggca atgaggaaca gattaagttt tcaaaaaaat atcccaagcg ttcttactat
     6001 tgtaatcttt atttgcagta tgagaatttt gagagaacag gtgaaatgca ttttactcca
     6061 ccggtacaaa ctatttacgc cactcgtcag gcattaaatg aatattttga agtgggtgaa
     6121 gaagctaagt ttgcccgtca caaaagagtt tttgaggcta ttcattcagg tataaatgaa
     6181 attggtctta aaagtgtaat aaagcgtgaa tggcagtcag gactggttgt ctcagttcaa
     6241 tacccagaag atcccaactg ggattttgag aaaatacatg attattgtta tgagcgtgga
     6301 tttacgattt atccaggtaa gatatcaact gaggatactt ttagaatctg tgctttagga
     6361 gagatagaag tagatgatat tgagaacttc tttaaagtac taaaagctgc attaaatcat
     6421 tataacgtca cattaccgat gtcatgattg cagaaatatt attgaagatt cgtcattttt
     6481 atttttccct tcgtggtata cacttccatc cggaaagtgt tatttctgga gtgcctattc
     6541 gtagctttcg cttagtaggc aaatatggca atattaattt gaggtgatgc attaggagtt
     6601 ctttattctt ataaaaaggc atcggtagtt ataggagata atgtttgtgt agggtaattt
     6661 gcttttagtg ggagagacca tattagaatt gcggtaaggg gcgaagaaga taataaccaa
     6721 ttagtgagaa tattggaaaa atataattga tatcggtaaa tgtagttgtt tttatactgt
     6781 atttaagtaa tggaaaatct aaagcagaaa actgtatcag gaataatgtg gagcgctata
     6841 gaacgtttct ctttacaagg agtacagttt ataattcaaa taatattagc tcgtttgtta
     6901 ctaccatcgg attatggtat gatcgggatg ttagctattt ttcttcaagt cgctcaagta
     6961 tttatagata gcggttttac aaatgcttta atccagaaaa aagatagaac tgaagaggat
     7021 tttgccactg tcttttattt taatattctt gtcgcagtat tattctatgg tatattgttt
     7081 ttttcggctt ctttgattgc agacttttat aatatgccga ctttagttct tgtaattcgt
     7141 tttatagcat tgtcgttgat aataaatgct ttatcggcta ttcacagaac gaaattaatt
     7201 atttctgtaa actttaaaac tcaatctaaa atttcattag gtgcagcttt tatatcaggc
     7261 gtgattggaa tatggatggc ttatgtcggt tgcggggttt gggctttagt ttggcaaact
     7321 ctcttaaata gtataatttt gacaattttg ttttactgtt tagttcattg gaaaccttta
     7381 catactttct ccaaaagttc ttttgaaaga ttattcaatt tcggatctaa attattgatc
     7441 tcaagtctta tcaatacagt atatcgtaat ctgtatacca ttgtaatagg aaaaaagttt
     7501 tctgttgtag agcttggtta ctatacaaga gcagaacaat ttgctatttt tccttccaat
     7561 aatttaaatg ctttagtttc tagagtagcg tatcctattt taagttccat tcaagatgat
     7621 gataaatgtt taacaaacgc atatcgaaat tatatcagat tatcctcata tataattttt
     7681 cctttaatgg taggtttact tgttttggct aatcctatta ttagtctatt gttaacagat
     7741 aaatggtctg gggttgttat tcttttacag atattatgtt tggattggat gtttgatcat
     7801 ttgagccaaa ttaatttgaa tttattatgg gttaaaggaa gatctgatct gtcgttacgt
     7861 cttgaaataa taaaaaagac gattgctata ttcattcttt ttgtgtcaat tccatttggg
     7921 cttgaggtga tgtgttgggg tagagttatt tactctctga tagcgacata tttgaataca
     7981 tattatacta attctcttat tgatttgacc ttaaagttgc aagttaaaga tgtatttcca
     8041 agtttaatac tctctttcat aatggggggg atcgttttta tatgtatttc tttctttgaa
     8101 actgatatag taaaaattgt gattggatgt attactggga tgtccttcta tattttactt
     8161 tcttttcttt ttaagctaga ttcttttttt tgtattttaa cattgatcat taaaactaaa
     8221 aacatagatg aaaatattaa aaaagatttt tcaagtaata gtaaagataa ttaaccattg
     8281 tgtgccagtt gatagtagat cattgtattt tattcctcat cctaattgta gaacagataa
     8341 atatgatatt ataaattatt cgtcagataa tgttctcgtt ctgttaaatt atttgctaaa
     8401 aaaagatagt gctgaatatt ataaaatata tgttgaaatt tatgattctt ctcgtatttc
     8461 agaatatcaa gaatatattt atggcataaa tcctaatatt aggtgtactt ttttatgtgc
     8521 atgtgttgga cgttttttct ttaataaagt atcttttaag gatatgttgt atgccttttt
     8581 ttgtttttgt agagcaagta aatgttttac agctactttt tattatgatt tttcatttaa
     8641 aaaacgctct caacagatta tttgtttggg gtattatact ccattcaaag atgattatca
     8701 tatgggagat cattcttatg ataaatttcg taatacaaca tgtaactcat ttgattactc
     8761 tattgctact tcttgtttaa gtgctagaat aatttcaata gattgtggaa tctcatatga
     8821 taaattcaaa gtcttaggat ttcccagaaa tgatttgttg atatcgaaaa ataattgcaa
     8881 tgttattaaa agagaaattt cgaaatttgc gggatatgat gtaactaaat atatagttta
     8941 tactccaact tttcgtgatt atgagactgt tactgaaggt aatttgcgtt caatactcgg
     9001 atatgttgat tgtgatttgt tgaagttatc gaaaatacta ttgaagttta atgcggcttt
     9061 aattcttaaa ttacatcctt tgcagaataa aacagtctta aaaaaagatt tacccaaagg
     9121 tatacttgtt tttgaacaaa catataaata tggattgtat gatcttttgt cattttcaga
     9181 tggaatgatt actgattata cttctaccta ttttgatttt ttattggtaa ataagccagt
     9241 catatttaat ttctacgata ttgaagaata tcgtagagta agaggtttct catttgagcc
     9301 aatagaattt ttttgtgcag gtgatattgt ttacaattat aatgaattga tagatgctgt
     9361 gatgggactt ctggctggga aagatattca tgctgaacat cgacgtcata tttctttatt
     9421 gatgaatcaa tttcaagatg ataattcaac aaagagaata tgtgacatat ttttaaatga
     9481 aatataataa ataaaatgaa ttatgcattt gtggtgcagg cacgtttagg ttctacacgt
     9541 ttgcctggaa aaatattgaa acctttctat ggtaatcaat cgattcttga cttaatggtt
     9601 cataagcttt ctgctatatc gaatattcca gtaattattg ctacaacaaa ttctgttatc
     9661 aatgaaccta ttgaaaagaa ggcacttgca ttaggggtaa agtgcttcag aggtgaggag
     9721 aatgatgttt taaaacgatt cattgatgtt gctgaatatt ttgatataca gggtatattc
     9781 cgaatatgtt ctgataatcc atttttagat gtacatgcgg caaggcaatt ggtcgaaata
     9841 gcaatgaaat cttgtaacga ttatataagt tttgatattg atggtactcc atcaattaaa
     9901 actcatttcg gtttttgggg agaatttgta acgcttgatg cgctgaagcg agttatagga
     9961 tttactgatg atttattgta tcgtgaacat gttactaatt atatatatag tcatcctgaa
    10021 ctttttaata ttcaatggat ttcaggatct ccagtcgtgt caaaacatca taatattcga
    10081 ctcacgattg atacgttaga agatttttct gtagcacaga gaatatatag ggatttacaa
    10141 gaaaaaagag tggaaatatc gatagaagtg attgtagact atgttcgaag acatgcagaa
    10201 tacattcaac tgatgaaaca acaaataaaa aaaaattcta aataatgaag aatacttata
    10261 ttattggtga aatagggcag aatcataatg gttctgttga cttggctaag ttgattattg
    10321 aattaatctc acgacctgta catgaggatg tttttggtat ggatttcatg ccaatgaatg
    10381 ctgttaaaat gactaaaaga gatttatcag aagaattggc tgtttctcaa atgaatcaaa
    10441 tatatgacaa tcctaattct tttgggcgta cttatggtga acatcgtgct tttcttgagc
    10501 ttgatgatca agcgcatttt gagatttata aatatgctaa gtcattagga ttagatttta
    10561 tcgagacgtt atgtgccaaa ggatgtctgt ctttgcttaa actgttcaca ccggataggc
    10621 taaaagttgc tagtcgtgat ttgactaact taccattgct tgaagcatta gcagaaactc
    10681 atattcctat tatattatcg acaggaatgg ctggtcaaag agaacttgac aatgcattag
    10741 atgtgataac gagatatcat agtaatatag ctattctaca ttgtgtatct cagtatccaa
    10801 ctcatccaaa taatttgaat ctacgtacaa taacatattt gaagaagcat tacaataagt
    10861 ttgagatagg tttttctgat catacaatag gtatttctgc tgctacagct gctgtagcga
    10921 tgggagcgga aattatagaa aagcatgtaa caattgatcg gcatatgaaa ggaacagacc
    10981 agcttggctc tttaggtcca gatggggtta atcgtatgat tcgagatatt cgcatagcag
    11041 agtgttggct tggtactgaa gatctttata tagaaaaagg ggtggagaag tctaagataa
    11101 aacttgaacg ttctattgcc actcgaaaat atattccagc aggtagtatt attcaagagt
    11161 cggacattca tttactgagt cctggtgatg gttataaatg gatagataaa aaaaatgtaa
    11221 ttggtcattt tgctaaacaa gatatatcag cgaatgaaat aatatatcct gattttattg
    11281 aatagatata ttcctactgc aacttgtatt acggtataga gtactgcctg ctataagcta
    11341 agtagtgatt aataaataag ggtaaaatac taaaaaaatg aaagagataa agcttatact
    11401 tacagatatt gatggcgttt ggactgatgg cggaatgttt tatgatc
//
