LOCUS       c00071_gnlPro..        13087 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EMFAMHHO_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:49:13
            Original ID  :: gnl|Prokka|EMFAMHHO_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13087
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13087
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[116:3087]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      117..3087
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13087
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13087
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..86
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="FYVEKHKIEHIYADYMKNDCNFVRSKE"
     CDS             117..2345
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="Gly_radical (E-value: 4.8e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2359..3087
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 71.7;
                     E-value: 2.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="Radical_SAM (E-value: 6.4e-28, bitscore:
                     90.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLALLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3080..3457)
                     /locus_tag="ctg71_4"
                     /transl_table=11
                     /translation="VDTAHRYRGFSCWGYHYYIRKSGEIEPMRDEDTVGAHARGYNAIS
                     LGVCYEGGLDENGKAADTRTPRQKEALHRLVHELLQRYPEAKVVGHRDLSPDTNYNGIV
                     DPWERIKECPCFEVIGEFSIN"
     CDS             complement(3516..3683)
                     /locus_tag="ctg71_5"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(3743..4246)
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             4440..4670
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             4757..6871
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCRIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(6941..7246)
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(7227..7400)
                     /locus_tag="ctg71_10"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLKTEITPKKEIDKAK
                     ILRKEYYGSKNK"
     CDS             7417..7833
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFYFSPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(7949..8260)
                     /locus_tag="ctg71_12"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(8232..8573)
                     /locus_tag="ctg71_13"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             complement(8666..8920)
                     /locus_tag="ctg71_14"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             complement(8938..9072)
                     /locus_tag="ctg71_15"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLGLIDQKKELSSN"
     CDS             complement(9190..10548)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg71_16"
                     /sec_met_domain="MFS_1 (E-value: 3.2e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(10564..11484)
                     /locus_tag="ctg71_17"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 tattttatgt tgaaaagcat aaaatagagc atatttatgc tgattatatg aaaaatgatt
       61 gtaactttgt gcgctctaaa gaataggata actacaacct ctaattttat cattttatgg
      121 aattaaacaa gatctttaaa gacggtcttt ggagcagcga aatcaatgtc agagatttcg
      181 taagtcataa catcactccg tattacggag atgcttcatt cctcgaagga cctacagaac
      241 gtaccaaagc cgtatggaac cgctgcctcg aagcgttggc agaagaaaga gaaaacaacg
      301 gtgtccgctc attagataat gttaccgtat caaccatcac ttcccacaag gccggatata
      361 tcgacaagga aaacgaactg atcgtcggcc tgcagacaga cgaacttctg aaacgtgcca
      421 tcaagccttt cggaggtatc aacgtagtca gcaaagcctg tcacgaaaac ggcgtggaag
      481 tggacgaccg cgtaaaagat attttcactc actaccgcaa gacgcacaac gacggagtat
      541 tcgacgtata tacggaagaa atccgttcct tccgttcgct gggattcctt accggacttc
      601 ccgacaatta tgcacgcgga cgcatcatcg gtgactaccg ccgtatggct ctttacggca
      661 tcgaccgtct gatcgaagca aagaaggaag atttgcacaa cctcaccggt ccgatgacag
      721 aggcccgcat ccgcctgcgc gaagaagtgg cagaacagat caaggcactg aaagacatga
      781 aagtgatggg tgaatactac ggtctcgacc tgagccgtcc tgcttacacg gcacaagaag
      841 ccgtacagtg ggtatatatg gcttaccttg ccgccgtcaa agaacaagac ggtgccgcca
      901 tgtcactggg taacgtttct tctttcctcg atatctatct ggaatatgaa ctgagcaaag
      961 gaaccatcac cgaatcattc gcgcaagagc tgatcgacca gtttgtcatc aaactgcgta
     1021 tggtccgcca cctgcgtatg caatcataca acgacatctt tgcaggcgac ccgacctggg
     1081 taaccgaatc tctgggcgga cgtctcaacg acggacgtac caaagtgaca aagacctcct
     1141 tccgtttcct gcagacattg tacaacctcg gcccttcacc ggaaccgaac ctgaccgtac
     1201 tctggagccc ggaacttccg gaaggattca aagaattctg tgcaaaggtt tctatcgaca
     1261 cttcttctat ccagtacgaa aatgacgacc tgatgcgtga agtacgtcag tccgacgact
     1321 acggaatcgc ctgctgcgta tcataccagg aaataggcaa gcagattcag ttcttcggcg
     1381 cccgttgcaa cctggccaaa gccctgttgc ttgccatcaa cggcggacgt tgcgagaata
     1441 ccggtacagt catggtgaag aacatccccg tgctgaccag cgacacgctg aagttcgaag
     1501 aagtaatgga caactacaaa aaagtgctga ccgaaatcgc ccgcgtatat aacgaagcga
     1561 tgaacatcat ccactatatg cacgacaagt attactacga gaaggcccag atggctcttg
     1621 tagatacgaa cccgcgcata aacctggctt acggtgtagc cggactttcc atcgccctcg
     1681 attcactgtc tgccatcaaa tatgcgaaag taactgcccg ccgcaatgat atcggtctga
     1741 cagaaggctt cgacatcgaa ggagaattcc cttgcttcgg taacgacaac gacaaggtag
     1801 accaccttgg cgtagacctg gtatacttct tcagcgaaga attgaagaaa ttgcctgttt
     1861 acaagaatgc ccgtcctacc ctctccttgc tgactatcac ttccaatgtg atgtacggca
     1921 aaaagaccgg tgctactccc gacggacgtg ccaaaggtgt tgccttcgct ccgggtgcca
     1981 acccgatgca cggacgcgac aagaatggtg cgatcgcttc tctgagttct gtagcgaaac
     2041 ttcgttaccg tgactcacag gacggtatca gcaacacctt ctctatcgtt ccgaaatcac
     2101 tgggtgctac ggacgaagac cgtatcgaga acctcgtaac gatgatggac ggttacttca
     2161 ccaaaggtgc ccaccacctg aacgtaaacg tactgaaccg tgatatgctg tacgatgcca
     2221 tggagcatcc ggagaactat ccgcagctga ccatccgcgt ttccggctat gccgtaaact
     2281 tcgtgaagct gagccgcgaa caccaactgg aagttatcag ccgtagcttc cacgaacgta
     2341 tgtaatctat tactctatat gatgataaac gtacattcat acgaaagtat gggaacattc
     2401 gacgggccgg gcttacggct cgtcgttttt cttcaaggat gcaacttccg ctgcctctat
     2461 tgcgccaatc cggatacgat agcaggaaag ggaggcacgc ctaccccacc ggaagaaatc
     2521 gtccgcatgg caatgagcca gcgccccttc ttcgggaaac gaggaggaat cactttctcc
     2581 ggaggcgaac cgacgtttca ggcgaaagca ctcgtcccgc tggtccgcga actgaaagaa
     2641 aaaggcatcc atgtctgtct ggacagcaac ggaggacttt ggaacgaaga cgtagaagaa
     2701 ttattcagac tgaccgatct tgcgttattg gatataaagg aattcaatcc caaccgccat
     2761 cagacgctca ccggaagaag caacgagcaa accatccgca cggccgcctg gctggaagaa
     2821 caggagaaac ctttctggct acgctacgtg ctagtgcccg gatacagcga ttttgaagaa
     2881 gacatacgcg cactgggaga agcactcgga aaatacaaga tgatccaacg ggtggaaata
     2941 ctgccttacc atacactggg cgtacataag tacgaagcga tgggacagga atacaagatg
     3001 aaaggggtaa aagaaaatac ccccgaacag cttgaaaaag ctgcggaggt attcaaagag
     3061 tatttcacta cggtagtagt taattaatgg agaattctcc aatgacctca aagcaagggc
     3121 attctttaat ccgttcccaa ggatctacaa tcccattata gttggtgtcg ggacttaagt
     3181 cccgatgccc tactacttta gcttccggat aacgctgcaa caattcgtgt accaagcgat
     3241 gtaacgcctc cttctgacgg ggtgtacgcg tatccgccgc ttttccattc tcatccagac
     3301 cgccctcata gcatacacct aagctgatcg cattatagcc acgtgcatga gctccgaccg
     3361 tatcttcatc ccgcatcggc tcaatctcgc ccgacttgcg tatataataa tgataccccc
     3421 agcacgaaaa gccacgataa cggtgagccg tatccacatc ctttgccgta aagtcgcaat
     3481 cgacacgggt ggcggaacaa tggatcacaa tcagactaat ctttctcatg ctccttttcc
     3541 ctttccgtcg ttttcacttt gcacacctcc ttacaagtag tatgatagcg cacttctctc
     3601 accaccctgt cccgctttct ctttccgaag aaaggaatca gatacatgat cacatctaaa
     3661 atccggttta ctatttcttt catcttatca aaatattaat ggaagttatt ctaattcgtt
     3721 attaccttga cccgtctgcc aattataccg tagggtccgg agcctcttca tcaccggagc
     3781 catcaccacc ggaatccgga ttcttgtcag ggtcttctcc cccgccatcg cctgcacccg
     3841 cctgcgccac cgcacgagtc tgcacttgct gataactcag aatcttcatc aactccgcca
     3901 gcgtcttacc ggggcggaaa ataagatgcg cccccttaat cattgaaccg gaaaattcct
     3961 tgaccgatgc cgcaccttca ctgttcagtc ctatctgcaa actgcccaaa tcgcccagtc
     4021 tcgcaattct tcctgccttc aacgcacgtt tcacttcgta aagaataccc gaaatagccg
     4081 cacgtacatc cgtttccgta caagtagaac gactggtgat cgcttcgcac aactcctcaa
     4141 agtccagctc acccgacgcc tgcgcctgtg cataatactt tgccggttcg ctcttttttg
     4201 caggattctt gcgcggcacc actgaataag atactgtcat tgccataata aaataatttt
     4261 aaagtttata atacatagga tgcatcccct tcttgttaac agcacaaaga taagggtatc
     4321 cggacaagcc atattcccca acgaagtttc ttgattccca acgaataaaa acgaagtcaa
     4381 acctttgaaa aacaaggaat tttatgtaac tttatagcat aaaacaagaa gaaaacatca
     4441 tgaattacaa agaagattct ttccttatcc gcacctatac caaagcggaa ctggctcacc
     4501 tttacaatcc ccatgtctgc ctcaaagttg ctttacaaat acttcgtcgt tggattattt
     4561 acaacctccc tctcctgcac gaactcgaac aggaaggcta ccgcgcacgc aaccgtctcc
     4621 tttcgccgaa acaagtggca actatcatac actttttggg cgaaccgtag taacttattg
     4681 ccattttata caaagttcct ttacacattt ccgcaaagaa gttcctttgc atcgacaaac
     4741 aataatcaaa ataaaaatga aacatttcac catatttcaa ggtttctact acgcaatagc
     4801 agagatgacc gaagaagaaa tagtgtccac tatcggcagt tttacctacc gggaaaaagt
     4861 cgaagaaata cgccgcatct ttgcagagca aggagaaaag gctgccaatg agaagaaaaa
     4921 agaattgccg gcaatcgcct tctccgccag ctaccgagga aggcgtacca aagtgaacct
     4981 cgtcaaatat ctgggacaca tcgtgataga catcgaccat ctcagcaaag aagaattggc
     5041 gcgcatcctc cctatcatca agagatgcaa ttacacccgc atcgccttta tcagtcccaa
     5101 agggatgggc gtgaaaatca tagtacgcgc atgccatccg gatgagacat tgcccgaaac
     5161 ccttcaggaa atagaagact tccatcatgc agcttacacc agactcgttt ctttttacac
     5221 cgaactctgt cggatagaaa tcgacacctc cggtcaggat gtggcacgca cttgtctgtt
     5281 ctcttacgat ccggagattt atttcaatcc gaacgctgac gcttttcttg tagatcaacc
     5341 tcaggcatcc tacaaggttt caaatcgtaa aaatctctcc ggcagtaaac aacagactcc
     5401 tccggacggc cccccgacga atgaagacac agcgctcaac gcccattccg ctaacgcttc
     5461 tctggtgctg actttaacct actatcacaa caagtccgaa aaatacatag tgggcaaccg
     5521 gaacaattat ctgcaccatc tctcatgtac cttcaatcgc tacggcattc cgcaggagga
     5581 agcatccgcc tttatcaaaa gccagtttac agactttccg gcggacgaga cagtctcttt
     5641 gatcaatagc gcctacgctc ataccgacga atttaatacc tgtaaactga atggcacgca
     5701 gaaacgaata ttacggatag agcaatatat cagcgagcac tacgaaacac gctacaacga
     5761 agtgctgcat atcatggaat atcgcagaag gcatcccgac accgagaaac cggagccttt
     5821 ccgcatcttg gatgagatga tggaaaacag tatctggata gaaatcaacg aactgggata
     5881 tccctgcact gtcaaaacaa tcgaaaatct gatttactcc gatttcagcc agtcgtatca
     5941 tcccattcgc gagtattttg aattactgcc cgaatgggac ggaaccgact atatccgtat
     6001 cctggcggat agtgtccaga cgagtcatca ggagttttgg gcggaatgcc tggaacgtta
     6061 tctggtagcg atgtgcgcag cggctactca ggagaatatt gtcaatcaca cggtacttct
     6121 gctatgcagc gagatacaga acataggaaa gactaccttt atcaataatc tcctgcctcc
     6181 cgaactgcgt gcttatctct ctaccggact aatcaattcg aacaataaag atgatttagc
     6241 caaaataacg caggctatgc tgatcaatct cgacgagttt gaagggatga gcggccggga
     6301 actgaatgca ttcaaagatt tggtaacgcg caaagtgatc agtttccgtc tgccttatgc
     6361 acgccgttcg caaaacttcc ctcatacggc ctcttttgca ggaacctgca attatcagga
     6421 agtgcttcac gacacgacag gcaaccggcg tttcctttgt tttcatcctt attccatcca
     6481 atttattacc atcaattatg cgcagctcta tgctcagatc aaatatctgc tgaataagcc
     6541 gggatatcaa tactggttca cgcaagcgga caatgaacgg cttgaagaga ataacgaggc
     6601 tttcatcttt cattcaccgg aagaagaaat ggttcttacg catatccgca agccggaacg
     6661 tttcgagaag gtttattatc tgactgtcag tgagattgcg gaactaatac gtgagcgtac
     6721 cggttatcag tattccatcg gatcaaaaat acagttgggg aaggtgatga ctaagcacca
     6781 ttttgaatct aaaaaaggaa ataacgggcg ccgatatgcc gtatttatta tagatatcga
     6841 gcaggtaaaa tcaaacaggc tgtatgaata gaagcgggaa agccttgtga atatagcaaa
     6901 atgcagagtc atcttgacag atactctgca tttattgttt ttacaaaatc attgaaaatt
     6961 cgattttaca gcctaacgca ttcattatac gatagaaagt agatacttta ggctctgtct
     7021 gaccactttc tactcttgaa atataagaac ggtcagaacc gatacgccgg gctaattcag
     7081 cctgagtgat tttagccttt tttcttgcgt cctcgataat ctgtcctgta taaaaggcgt
     7141 aggccttttc ttctgcctct gcacgagaag ctgttccttc cttaccaaaa cgctcatcta
     7201 ttaatgcact gacattaaag aattcctcat ttgtttttgc ttccataata ctcctttctt
     7261 aatatctttg ctttatcaat ttctttcttt ggtgttattt cggttttcag cacatacaat
     7321 atcttatctt gggtgccagc atctaaattt tcaaagaatt ctttgaagta tcctttatat
     7381 gctattattt ctcttttcat aacgcaaata taagaaatgt tgttcaacta tacaacacat
     7441 ttcctcgttt tatattattt ttcatcatct tcacccccaa aagtgagagg agtgagagag
     7501 gaattgaaac tttttctatt ttatttcttt atttctactt tctatatttc tctaaaaaaa
     7561 atacgaatgt tagaaatcct ctctcactcc tctcactttt taccttttct ttctccaaaa
     7621 agacggcggg aaatcggaaa aacacaaccg tcttttttct atttctcacc gcattttcaa
     7681 atcagcccac caattgaagc agacttcagg aaatatttgt tatctttgat gtgcaaaaga
     7741 tcaaaagaat cagatatgga caacttgatg cgtaaacttc ctattggaat acaaaccttt
     7801 gaagatatac gaaggaagaa tatcttattg taaagatcgg aatggaattt agtgcagaaa
     7861 gccggaactt aaatcgttgg ttaatcgaag tgataggaaa gtaaaatatg aaaaaccgaa
     7921 ggattaagat atccttcggt tttttcgact atatacccat gattggtttt acgatttcaa
     7981 tcttcaatcc taatgcatta ataattcggt agaatgttcc tacacttgga tttatagctc
     8041 cgctttcaat acgtgagata tacgatttag ttgcattgat tctctttgct aattcagact
     8101 gagttacttt tgcttcccgt cgtgcatcca acagtatttg accagtataa aaagcgtatg
     8161 cctcttcatc gaacttttca cgttccggag tcccaggtgc tccgaactcc ttatcaagtt
     8221 ctgcgctgat atcagtcagc atgttgtttt ttgtactcat aatattcctc ctttattttt
     8281 aatgccttat ctatttctga tgatggggtt ttctgtgttt tcttatggaa gccattaaat
     8341 aaaacaacta tttgcccttc atcaaaaatg aaaaagatac ggtaaatgtt tccgttatat
     8401 gatatacgta gttcatatag accatcacgt ataaccttta taaatttgat aggcaaacgg
     8461 tcttctgttc caagcaatga aagcacatat ttcacttttt gaatttcctt ttctgtcaga
     8521 gtggcaagaa aatccttgta atattgaccg tatgctatta cttttcttct cattgtgcaa
     8581 atataataaa agtttcaata tcatacaact tttaaagtcg aatttatact gctaacgggc
     8641 ttaaattccc tctcaggtac tcattttatt cgaatttccc ttccgaataa tctgaaaact
     8701 ctccggcacg ttctttcttc tcatacgaga ccaacgtttc gatactgagc gctttcccgt
     8761 tcttagggct tatgacatct atcacacttg acaaggaccg gaacgtctgt tcgcaattcg
     8821 catctccatt atacgtcaac ctcccccggt caatggcacc tagaataaca gaaacatacc
     8881 gtttcggatc tccccgatat tcgataacag tgggcgtcat ttgttcttct tcccgaatca
     8941 gttggacgac aattcttttt tttggtcaat cagccccaac agttttttac tatgcacact
     9001 gatttgtgca tctacttcac gaagttcatt cttcaatgaa caaaacaatt catcactcaa
     9061 tgaattttcc ataaaaacga tttttattaa ttataaaaaa gccattccgg aaagcacagc
     9121 tattgcctgc ttcccgaaat ggtgactaat accttcaaaa acaatgactc tatttttact
     9181 ttaatgtact caatttattt cacttctttt ctctcctgca ttccaaacca acaaagcaaa
     9241 cactactgaa agcaaggctg caccaatcca aaaccaattg atatatgtaa aatcgtaaac
     9301 ttctactcca ttttgcaccg tcttctgacc ttcgatcaga atgccactca tcacatcctg
     9361 caaaccggct cctatataac tcgctatacc gacaactccc aaagcggctc ccgaagcatt
     9421 gctgggagca atatcgacag ccatcagtcc tcctaaaaaa caaatcagca ctccaatgcc
     9481 caaaccgaag agcaccatcg ccaaagcatc cacccaaaaa tgtacccccg gaaccaatag
     9541 aaacaaacaa agagcagaca cattcattaa tccgaatatc aaagccggaa cattacgact
     9601 gccagcaaaa aacttatctg aaataatacc tgagaaaacc gtacctacaa ttccgcatac
     9661 agaactgata gatataataa aactagcatc caaagtagaa taaccttttt gcgcttccag
     9721 atagaaaaca ccccagctat tgactgcata acggctgata tacataaaag cactggataa
     9781 tgcaagaatc caaatagcag gattcttcaa aactgctttc tgagctttat tgaattcctc
     9841 ggtttgctta ccggaaacgg aatgagcatc tgacgtcccc caccgatcta gcaaaaagcc
     9901 ctgactttga ggcgtatcac gcataaaagc aagcatcatc agaaaaccaa gcaaaccaat
     9961 cactcccgca ccgatcatcc cataacgcca tcccatccaa ctgaccagca aagcgatgga
    10021 tataaaagtc agagcttcac ccaaattgtg gctggccgac caaaagccat aaaaagtacc
    10081 tcgctcttta ctactatacc aacgagtcag cgacacaact cctgatgctg cccccatcga
    10141 ctgaaaccaa ccattcaacc cccaaaggag aacaaaagca aagaaagaat tcgtgaatcc
    10201 cagacataag ttgatcagag cagaacacaa taatccggta gacataaaac gctttacatt
    10261 gctacggtca gcaagaaagc cattggtcag cttaccgacg gcatatacga aaaaaaggca
    10321 ggaaccgata atccccagtt gggtttcggt aaaaactccg tcttctacaa tcggtttacg
    10381 gattacattc atactcaaac gacaaacata ataaatgcca tatccggtag tggcagacag
    10441 aaaggtagcc caacgaatac gcttgaaacg gacagagcgt tccggatcag tctctccccc
    10501 ggacaccgga ggagagattt tataaaaatc caatagttta aatcccataa agaagtctat
    10561 attttaatga tacgcatctt ggccgttttc actacgcttc ttacgcgatt gcaaatattc
    10621 cagcagatag gcagtacggt ctgtctgaat gatggccgct ccgagtgtat cgatcagata
    10681 accatatcct tcgtccggat tctccaacga tttatcatca tcatgtccgc cagccatcgt
    10741 atcccacaac gtattatacc agattttact ttttcctttc aacttcgttt ttacttgctt
    10801 gggggcctgg caggtatccg atacaaatag aagttcaaaa gctacgggat gcagctccgt
    10861 cataaaatca tccagttgct tcattgctcc cggcttatcc aaatgaatga taggcatata
    10921 aatgatacgg tccagatatt tacctaagtc tttctttacg tctgccacag gcttggaacc
    10981 tttcatgata atctgatcca ctgttcccgt cttttcgagg atgggaaaaa tctcgtcaaa
    11041 tatcggatat gctttatcca gattgaccat cacacgacct ttggcaaccc ataaagcctc
    11101 ttccaaagta ggtacacgat gcttggtttt gagtgccgct ccatttttca gatagagtgt
    11161 ccggatagaa tccaatgtcc attcggctac ctttcctttt ccggtagtcg ttcggtccag
    11221 cgttttgtca tgcatcagga tcaattgacc gtctttggtt ttctgaacat ccagctccac
    11281 tacgtcagct cccagacgaa tggaactttc aatagcggca agtgaatttt cgggtgcgta
    11341 acgccagtct gcccgatgag ctacaaccgt gatttcttta ttgtcagggt tcgttatctt
    11401 cgcataaatg gctttcaccg gttcgtctgc cgacaggcag aaaggaaatg cgaataagat
    11461 tcctatcatt atatatttct tcatatctat atgtactatt atctgtatcc tttagacttt
    11521 aaatatttgg cagctacttc agcatagtct gtttgcacaa tgttgatgcg tttgttaatc
    11581 attcccacca aaccggagta gttttccgac aacatattgg tatcattcgc tccgacaatg
    11641 ttggagaaaa gaagccagcc tttatcttta atctcattaa ccatcgttcc acccatagca
    11701 tctgacgtag acagctgcat catttgtaca ttatcagtgt aggatgagga gaagtatgtg
    11761 atgtcatcgg tagctttcgc catcgggtgc aacagcaaac tactgttggc tgccttcaaa
    11821 tcaaatgcat aattgcgatt gttggataca tacagcaaag tggaaccttc catatccaat
    11881 tttttaagca atgcgacgat cgtatttacc gcaacattct tgttgacaat atccagatta
    11941 taataaactt ttccttttcc tttcttcatc gcttcctcca aagtcgggat tcgttcgcca
    12001 gttatattgc cggatgcatc tttcagataa aattgttgta attgctgata agtaaagtct
    12061 cccaccgcac cgctaccgtt tgttgtccgg tcgatggtgt tgtcgtgcat caataccaac
    12121 acaccgtcag aggtcggccg tgcatccagc tcgatcatct caactcctgc tttgaccgag
    12181 tgttctatcg caggtaacga gttttcggga atcccctctt tcatcccttt ttgggtattt
    12241 ccacgatgcg cgcagagcca cactttataa gaggtgcttt caaacagact ctttaaatct
    12301 gctttcaaat tccccgtcac aggcaactgt cctccttctt ctccaccggg attctctcca
    12361 ttccctcccg attgggctcc ggagtgacgt ctgtccttcc ctttcatcgg ccaggcagag
    12421 gttgcggccc cggtaattcc ctcatcttcc aaagctacca acacgctctt tgtagggtcc
    12481 accgtattgg tgactccgat ataaatcgct ccatccggtc cgatggtagg cgaactccag
    12541 attttaccga ttcccgcttc ccaatctcct tttaaaggag agtcactttc actaatcaac
    12601 gcagcaaggt cttttttcag aatcaattgt tcatccgatt cttccggttt aatgatataa
    12661 taattgccgg actgggtgcc gaaatgtatg tttcctgctt gatcaattgc cgcacaaccg
    12721 cttacatctt ccgcaatgcc gtaatgccat tggatagctc ctcccggaga caaagagatg
    12781 attcctccgg ttgcttcccc cggagcacgt ttcactgtaa cgataatgct tccgtcgagt
    12841 cctatcacaa caccgccttg atccagcgtg ccgacattgc ccaaaggagt acgccacttc
    12901 tccactccat cacttcctat agcaaatgcg ctacttccca ttcctgcaaa cgtagctgtt
    12961 ccgtaaatag taccagcctc atctactgcc ggagaaccgt tcatattttc tgacggctta
    13021 tcatcgccgg agctaaatac ctgccaagcc cacattacat ttccaccggc attcaacgca
    13081 gaagcag
//
