LOCUS       gnlProkkaCBHCMGNA_15   11882 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBHCMGNA_15.
ACCESSION   gnlProkkaCBHCMGNA_15
VERSION     gnlProkkaCBHCMGNA_15
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:01:14
            Original ID  :: gnl|Prokka|CBHCMGNA_15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11882
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11882
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2608:6882]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2609..6882
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11882
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11882
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             193..771
                     /locus_tag="ctg15_1"
                     /transl_table=11
                     /translation="MFHYPGVPQLYPFVNNSINKSWYALRITYSRELAFKEYLDSRGVR
                     NFLPMRYEYVFRGERKIRKLVPVVHNLVFVYATRSEVDEMKSTVGASLPIRYIMDRETR
                     QPITIPEVQMRSFIAVAGNYDEQVVYLDPSVVSMKKGDRVRVTGGIFEGVEGEFVRIKG
                     DRRVVVSIQGVMAVATAFIHPSLIELIKN"
     CDS             830..1315
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MLSLQSEIDSLCAVSHELLHLGLDGEPIYSDRFRQLNTDVYHRCE
                     HLFGSHGRTLEEEASLCIALLTGYNATIYNHGDKEDKIQSVLNRSWDLLDTLPASLLKC
                     RLLVACYAEVFDEELAAEAHAIIDGWKDRELTREECEIVEHLKSLEANPYPYSELHE"
     CDS             1312..2595
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             2609..3307
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.8e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             3327..4628
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.9e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 6.9e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             4640..5776
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.3e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             5773..6882
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.3e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg15_7_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_7"
                     /sec_met_domain="Aminotran_5 (E-value: 1.2e-31, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAQYLLFIR"
     aSDomain        5863..6666
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_7_Aminotran_5.1"
                     /evalue="6.30E-34"
                     /label="ctg15_7_Aminotran_5.1"
                     /locus_tag="ctg15_7"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             6913..8277
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2.6e-15, bitscore:
                     46.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVFNSNKFFCWINQALITCVSRIICVIETLVPSKFSDKIRILR
                     SHEVVFYNVIGLTFFNSLGGLLTILTQVKLANVMGASHYGVYSYCLAIGEVGAMVVRYG
                     RHKTMVRDLIQYPVRNLQLISSTFIIGVINFLIFLGLVLVFHQDIDIQISVGTVLLICG
                     ACLISLDFQPVYESLNAMSWHSMYNLFQKLIFVIILWGIMLSPFTLSLNVLGIVFFFSW
                     ILVIVWQYKEITSFFHLKIISTCEWSKLFKLYRENFVVAFSCLFGIAFGPIIRIVLNNY
                     CNSREVGVFSAGLQILLIAQFILNQIGRIGNPMMAIIGKDNCSMKQRRLFVYRYLFIML
                     SSTLPFFIPFFFFPSLVVNMFFTEEYADLVIMLPILAVYLIALSVGVVYTQFLISMRKD
                     RLYFIIYVLGATLTILCAFLLIPILGILGATLSLCVPHALTCLCYWWFSANLLRK"
     CDS             8280..9182
                     /gene_functions="resistance (resist) AAC3 (Score: 59.5;
                     E-value: 1.6e-18)"
                     /gene_kind="resistance"
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MFVEKIRIRILLVRWIKTIFHISDLNLFLRDVRLYSSKLVYCKKF
                     TVVDLVNLMCEMGMKPGSTIVIHCAMKQFYNFSGTAEELIDAIIEKLGPEGTLCMPSYP
                     FDKKNENILFDVIKSPTAAGYLAETFRKRKGVKRSLNKLHSVCAFGKYADYLINEHHLS
                     KTCFDEKSPYYKLAKLNGLSFSLGLPKYYIGTIEHVCESLLCNELGFFRDCFLKEVNFR
                     YKDENQLEIYHKMWTCDRLYLRAHNSKLIDTYFDKEKFSRKRISNLRVSMFDVGYTVDR
                     LVDLAMQGKTLYSYPKFYK"
     CDS             9185..10423
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MPQIIFILGILIYRFFLDNVYIQTIAPFYAYQGLDYVGTNIDYWI
                     SWGVLIAFSLLMSLLLKYKEFFLSNILILLFLIRFVPFTSLLACKSLDNRLLLMELIYW
                     GAIFLFSLILKRPCLHFSFSKRYKLSTLRFSVVDIVLVFSVLIVLFVSGCYAHFRLNFS
                     LMNVYDLREEARDFSMPVLLKYLWSATGNVLPVLFVYYLIIKRRIVCCFIAFVILLNFS
                     VDGLKANIFKLFLCLLLHLVYKQNLIKMFPWLFALLCFFSLAEYYVFSTPLLSEFVVRR
                     VLYIPALLDSYYFDYISKYGPVFYQRGDVHIDFIIGEEYFGKASMRANNGLFTDAYMNL
                     GEIGCLVYPFVYVAFFKFCESSFEGVNVELVMFVIIIMVITLNSSEFTTSLLTHGLFAL
                     CLLLYFLPRKRYD"
     CDS             10493..11197
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MNIENSRIYFFLRNSVLYGMLQPIWRFYYRRCRKRAMKLYACELL
                     ENMKQILDKNNILFWLDFGTLLGAYRDKDFISYDCDIDIAILYEDAERVRNLLKNSDFC
                     LTHEYRVGKAGEVAQLSYKYKSLSIDICFYHKKNESMYCYLCSILPGVSIVNNRRCVVA
                     VAKCVVPCEKFADINFHKLIYHAPFPTEEYLAAHYGPNFMIPDSKFDYTKDAPNITNYA
                     IEELAGECIYND"
ORIGIN
        1 acgatcgtct tttgaaacac tttcgcttca taatagactc gtttacagat tgtaagatca
       61 gtaaagccct gtttttcaaa actttgtttt ctgttcttct ttttcaaact gtctctcctg
      121 tgatagggga gtacctgatg aaatgatata cgctgcaagg caaacaacag aattagcaaa
      181 cttgaccgga aggtgtttca ctaccccggt gtcccccaat tatatccttt tgtgaacaat
      241 agcattaata aatcctggta cgcccttcgt atcacctata gccgtgagct tgcctttaag
      301 gaatacctgg actcccgcgg agtgaggaat tttcttccca tgcgctatga atacgtattc
      361 cgtggtgagc gtaagatccg taaattggtt cctgttgttc acaacttggt ttttgtttat
      421 gccactcgca gtgaggttga cgaaatgaaa tccactgtcg gggcttctct tcctattcgt
      481 tatatcatgg accgtgagac ccgtcagcct attaccattc ctgaagtcca aatgcgtagt
      541 tttatcgccg ttgccggtaa ttacgatgaa caggttgttt atctggatcc ttcagtcgtt
      601 tccatgaaaa agggagaccg tgtccgtgtc accggtggca tcttcgaggg agttgagggt
      661 gagtttgtcc gtatcaaagg tgaccgccgt gtggtggttt ccatccaggg ggttatggca
      721 gttgccacgg ccttcattca tccctcttta atcgaattaa taaagaatta aaaactctgt
      781 gaactctgtg ccctctgtgg tgcatattcc aatacgtaaa taaatcacca tgttgtcttt
      841 gcaatcagaa atcgattctt tgtgcgccgt ttcgcacgaa cttctccatt taggtctgga
      901 tggcgaaccc atctactccg accgtttccg tcagttgaat acggatgtgt atcatcgttg
      961 tgagcatctt ttcggttcac atggacgtac cctcgaagag gaagcttctc tttgtatcgc
     1021 tttgttgacc ggctataatg ctaccattta taatcacggt gataaggaag ataaaatcca
     1081 gtcggtcctc aatcgtagtt gggatctctt ggatacactt cccgcttcgc ttttgaaatg
     1141 ccgtttgttg gtagcttgtt acgccgaggt ctttgacgaa gagctggcgg cggaggcaca
     1201 tgcaataata gacggttgga aggatcggga attgacgagg gaagagtgtg agattgtgga
     1261 gcatttaaag agcttggaag ctaatccata tccgtacagc gaactacacg aatgattcgt
     1321 tcctttcttt cccgttctcc cctttacgtt ttggctctct atgccagcgt tttgattttt
     1381 ctggtttata cttgtgccta tgcctaccgt aagccattta ccgcagccat ttatgaaggt
     1441 gagattcttt ggggattcga tgtcaaaatc ctgtatgtcc tttctgagat tatcggctac
     1501 gccctttcca agttcatcgg tgttcgtatt ctgccttcga tgaaagcggg tcaccgcatc
     1561 tattatataa tagggctgct tactttttcc gaagttgctt tgttgggttt tgcacttctt
     1621 ccggttcctt tgaaggtgtg ttctattttt ctgagcggtc ttcccctggg tatgatctgg
     1681 ggtgtcattt ttagctatat cgaagggcgt cgtatcagtg aaatattgaa tgtcgggctg
     1741 agcgttgctt tgatagtctc ttccggtttg gtgaaaacct tgggacaatt cgtgatggat
     1801 aatttgcatg tgtcggaata ttggatgcct tttaccaccg gtttgttggt ataccctgtt
     1861 atgttgcttt gcagctggct tctcaatcag attccggctc ccaatgagca agatatcata
     1921 cagcgtacca aacgtgctcc gatggatggt aaagacaggc gtaaattttt gaggcaattc
     1981 ttctggggaa tctgcatgct ggttgttttt tacggtgccc tgaccgtgtt ccgtgagctt
     2041 cgtgactctt tcgctgccga tatttggaag gagctccata ttgaaggtgc aatgatcttt
     2101 actcagacag aggttcccat tgccgttttt gtccttgtac tgatgttcct gattgtgttt
     2161 gtccgtaata accgtttggc tcttaatatc atttattgca ttgccgttac aggcggttcc
     2221 ttaatggttt tttccacatt gctttatgtg tacggttttc tttctcctat ttggtggatg
     2281 attctttccg gtcttggtct gtatatgggg tatattcctt tcacttacct gatagaacgc
     2341 ctgattgctt cccttagggt ggttagtacg gctgttttta ttatttattt ggccgattct
     2401 ttcggctatc tgggcactac gggtgtgttt atggtcaaga acttcgtttc tgctgacatt
     2461 tcctggactg tcatgctaat gcgtactgcc cttttttcag gatttgtttc tgtcctgtcg
     2521 atttttgcga tttactgtta tttcaagcaa caattgaatt cacttatatt aattccctct
     2581 gaaattcatg attaaaacag caatgatcat ggctgccggt cttggtaccc gcttcgggca
     2641 ttataccgag cttgtgccca aaggttttgt ggaggttggt ggaaaaccta tgattatccg
     2701 ctctatcgaa acccttcttt cctgcggtat cgaacgtatc atcctcggta cgggttataa
     2761 aaaagaggct tatgaagccc ttcaggcgga tttcccccag atagagacct gtttcagtcc
     2821 ccgctatgcc gatactaaca gtatgtacac tctgtacaat acgcgtgacg tgataggcga
     2881 tgacagtttc ctgctgcttg aatcggacct tgtttttgaa cgcaaggcca tcctctcgct
     2941 actggatgac gaattcccgg atgtgatgct tgtctcttct ctgaccaagt tccaggatca
     3001 gtattatgtg gaatatgacc gcaatcacat ccttacttcc tgttcggtag acaagaacgc
     3061 ccttgaggca aaaggcgagc tggtcggtat ccataaactt tccaatactt tctaccgccg
     3121 gatgtgcgcc gattatgcga ccatcctgga gtcccagcct aaactgggtt acgagtacga
     3181 actgctccgc atgtcccgtt ccgtttcccc tgtccgtgtg ctcagggtgg agggtcttaa
     3241 atggtatgaa atcgatgatg aagccgacct ttcgtatgcc gaggagcaca tcatccgcta
     3301 ttgttaaaaa caaatctttt ccatatatga acaagaaaat ctatgtcggt atgaccgcgg
     3361 atatcatgca tccggggctg atccatatta ttcatgaagc tactaaatac ggtgatgtca
     3421 tcgtcggtct gctgacggac aaggccatcg ccgaacacaa acgcctccct taccttacct
     3481 atgatcagcg taaggaggtt gttgagaata tcaagggggt ttttgaggtt gttccccagg
     3541 aggactggag ctatgttccg aatctggaaa aactcaagcc tgactatatc atccacggcg
     3601 acgactggaa aacgggcccg ttgcgcgagg tgcgcgaaca ggtttttgag gtgatgaacg
     3661 cccagggggg caaggtaatc gagatccctt atacccgggg catcaactcc tcctcgctcg
     3721 acaaggatat caaggcgatc gggactaccc ctgacgtacg tcttaagtcc ctccgccgcc
     3781 tgatccaggc caagcctgtg gtccgtatcc tggaggctca cgacggtctt tgcggtctga
     3841 ttattgagaa tcttgaagtc cagaagggtg ataagcgcga ggtctttgac ggcatgtggt
     3901 ccagcagcct gaccgactcc acgagtaagg gtaaaccgga tattgaagcg gtcgacctta
     3961 ccacccgttt acaggacctg aacaatatcc ttgaatgcac caccaagcct attatttttg
     4021 atggagacac gggtggcaag atcgaacact ttgtctttac tgtgcgcact ctggaacgtc
     4081 acggcatttc tgcggtaatc attgaagata aagtcggtct gaagaagaat tccctttttg
     4141 gtactgacgc tatccagact caggatagta tcgagggttt ctgcgataag atcagagcag
     4201 ggaagaatgc ccaggtcacc ggtgacttta tgatcattgc gcgtatcgaa agccttattg
     4261 ccggcaaacc catgagtgac gccctcgaac gtgcttatgc ctatgtacag gcgggtgcgg
     4321 acggcatcat gatccacagc aaggataagt cgggtgagga tatccgtgag ttctgccgga
     4381 ctttccgcaa agaatacgcc catgttccca ttgtcgttgt tccgacgact tatgaccatg
     4441 tgcacgaatc cgaacttcac gaatggggtg ccaacgtagt catttacgcc aaccaccttc
     4501 tccgtgccgc ttacccggcc atgatgaacg tggccaggac catccttgaa aacgagcgcg
     4561 ccgaggaggt ccgtccgctt tgtatgccta tcaaggaaat tctggaattg attccgggca
     4621 ctaaataaat cagacggtta tggtaagtgt agaaaagata tacgatacgt tccttcatca
     4681 cggtgttgac ttctttacgg gtgttcccga ttcccttttg aagaatattt gcgcctatat
     4741 cacggatcat gctccgcgtg gtaagcatat catcgccgcc aatgaaggtt ccgcggtggg
     4801 cattgcctgc ggttattata tggcttctgg caacgttcct ttggtttata tgcagaactc
     4861 cggtctggga aatacggtga atcccctctt gtcccttgcg gacgagaaag tgtacagcct
     4921 tcctcttctt ttgctggtcg gctggcgcgg tgagcccggc acgaaagacg aaccccagca
     4981 taagaagcag ggcgaggtta cccttgatct tctgaaagcc atgaaaattc cttttataat
     5041 tctggatacg gatgaagacg aggccctggc gcagatccat gacgcggttg tctcggcgaa
     5101 gagccggtcg attccccatg cgattgtcat ccgtaaagat acgtttggaa aatataaatt
     5161 gcgtcaggaa gccttgaatg actatcctct gtcccgcgag gaggcgttaa tgcaggttgt
     5221 cgaccacctc ggggacaatg acattgtggt ttccaccacg ggcaagctct cccgtgagct
     5281 tttcgagtac cgtgaatcga aagggcaggg gcacgcaagg gatttcctaa ctgtgggttc
     5341 catggggcac agttcttcca ttgccctggg gattgccctt gagaagcctg accgccgtgt
     5401 ctactgtctt gacggtgacg gtgcctttat catgcacatg ggtgctgtca gcaatatcgg
     5461 cgatctttct cccaagaatt acaggcacgt ccttttcaac aacggtgcgc atgaatctgt
     5521 cggcggtcaa cccacgctcg gtttccgtct ggatatcgcc tcgatagcga aaggttgcgg
     5581 ttatgcgcat gtactgactg cctccgacaa ggaagggctt tcgtgtgcgc ttgagaagct
     5641 gtccggcctg tccggcccgg ttcttcttga aattaaggtc cggatcgatt cacgtgatga
     5701 tctgggtcgc cctacgacta ctccggtaga gaataaagag cattttatgg catttttaaa
     5761 agatacgcat tcatgaatat cgaaagaaag atccttttga atccgggtcc cgccaccacg
     5821 acggatacgg tgaagctggc gcaggttgtt cccgatatct gtccgcgtga gaaagagttt
     5881 gcgggtatga tgaaacagtt acgtgacgac ctggtccgcg ttgcgcatgg agacctctcc
     5941 aaacatacgg ccgtcctgtt ttgcggctcg ggtacgatca atatcgatat ctgcctgaac
     6001 tctcttcttc ctgcggataa gaaagttctg gttgtcaata acggtgccta cagcacccgt
     6061 gcggtggaag tctgcgaata ttacggtctt ccccatatcg atttgaagtt ttccgtttac
     6121 gaacttcccg acctgtcggt aatcgaaaag acgctttccg acaatccgga catcgctttg
     6181 gtctatacca cgcaccatga aacgggtacg ggtatcttga accccatccg tgagatcgga
     6241 aaaatagccc attcgcacgg tgccgttttt gttgtcgaca ccacttcttc cctgggtatg
     6301 attccttttg atatcgggaa ggataatgtt gacttttgta tggcttcggc tcagaaaggc
     6361 cttcaggcca tgacgggtct ttcctttatc ataggtgatg aatccctgat acgtgcttca
     6421 agggattatc cgaaacgctc ctactattgt aacctctatt tacaatacga ttactttgag
     6481 aagacgggtg agatgcattt tactcctcct gttcaaaccg tttacgctgc ccgtcaggct
     6541 cttgatgaat attttgcagt aggtgaagag gctaaattcg cccgtcacaa gagggtcttt
     6601 gaagccatcc ataaaggttt gcaagagctt ggtcttcagt atgcgatcaa acgtgaatgg
     6661 cagtcgggtc ttgttgtttc tgtattgtat cctgatgatc ccctctggga ttttgataag
     6721 gttcatgatt actgctatga acgtggcttt acgatctacc cgggtaagat ttccacaacg
     6781 aatacattcc ggctttgtgc gttgggagag attgatgtgg aggatattga gaggttcttt
     6841 gaggtgatga gggaggcaca atatctccta tttataagat aggtcgttga ttggaagaaa
     6901 tgtttcttta gaatggatgt tgtgtttaat tcaaataaat ttttttgttg gataaatcaa
     6961 gctttaatta cttgcgttag taggataatt tgtgtcattg aaactttggt tccttctaaa
     7021 tttagtgata aaataaggat tttaagaagt catgaggttg tgttttataa tgtaatagga
     7081 ttgacattct ttaattcgtt gggaggatta ttgactattt tgacacaagt aaagctagcc
     7141 aatgtaatgg gagcttctca ttatggggta tattcatatt gtttagctat tggagaagtt
     7201 ggtgctatgg tagttcgcta tgggcgacat aaaacaatgg tacgagatct tatacaatat
     7261 ccggttagaa atttacaact tatttcttcc acatttatta ttggggtaat taattttttg
     7321 atttttttag ggctagttct tgtttttcat caagatatag atattcaaat ttctgtagga
     7381 acagtgttgc ttatatgcgg tgcttgtttg atctcattgg attttcaacc tgtatatgag
     7441 tctttaaacg caatgagttg gcattctatg tataatttgt ttcagaaatt gatatttgtt
     7501 attatcttgt ggggaataat gctgtctcca tttactttat ctttgaatgt attaggaata
     7561 gtattcttct tttcttggat actagtaatt gtatggcaat ataaagaaat aacttcgttt
     7621 tttcatttga aaatcatttc tacatgtgaa tggagtaaat tatttaagtt gtatcgtgaa
     7681 aattttgtag ttgcatttag ttgtcttttt ggaatagctt ttggaccaat tattcgtatt
     7741 gttttaaata attattgtaa ttcacgggaa gtgggagttt tctctgcagg tttacaaatt
     7801 ttattgattg ctcagtttat attaaatcaa attggacgta ttggtaaccc aatgatggca
     7861 attattggaa aagataattg ttctatgaag caacggagac tttttgtata tcgttatttg
     7921 tttataatgc tttcaagtac tttgcctttt tttataccat ttttcttttt tccttcttta
     7981 gttgttaata tgttttttac tgaagaatat gctgacttag ttataatgtt acctatttta
     8041 gctgtttatt tgatagcatt gtctgtagga gttgtttata ctcaattttt gatttcgatg
     8101 agaaaggatc gactttattt tattatatat gttttaggag ctactttgac tattttgtgc
     8161 gcttttcttc ttattcctat attggggata ttgggggcta ctttatcttt atgtgtacct
     8221 catgctttaa cttgtttatg ttattggtgg ttttctgcta acttgttaag aaagtagtta
     8281 tgtttgttga aaaaataaga attcgtatct tattggtacg ttggattaag acaatatttc
     8341 atatatcgga tttgaatctt tttctgcgtg atgttagatt atatagttct aaacttgttt
     8401 attgtaaaaa atttacagtt gtggatttag tgaatttaat gtgtgaaatg ggaatgaagc
     8461 caggatctac aatcgttatt cattgtgcta tgaagcagtt ttataatttc tcaggtactg
     8521 cagaggagtt aattgatgcg attattgaaa aattaggacc agaaggtaca ttatgtatgc
     8581 cttcttatcc atttgataag aagaatgaaa atatattatt tgatgttata aagagtccta
     8641 cagctgctgg atatttagca gaaactttta gaaaacgaaa aggtgtaaaa cgaagtttga
     8701 acaaattaca ctcagtgtgt gcatttggta aatatgctga ttatcttatt aatgaacatc
     8761 atttatctaa gacgtgtttt gatgaaaaat ctccttatta caaacttgct aaactgaatg
     8821 gcctttcttt tagtttgggt ttgcctaaat actatattgg aaccatagaa catgtttgtg
     8881 agagtttgtt atgtaatgaa ctaggctttt ttcgagattg ctttttgaaa gaagttaatt
     8941 ttagatataa ggatgaaaat caattagaaa tttatcataa aatgtggacg tgtgatcgtt
     9001 tatatcttcg agcacataat agtaaactaa ttgatactta ttttgataaa gaaaaattta
     9061 gtcggaagcg aatttcaaat ttgagagtta gtatgtttga tgttggttat actgttgaca
     9121 ggcttgttga tttagctatg caagggaaga ctctttattc ttatccaaaa ttttataaat
     9181 aagaatgcct cagataattt ttatattagg tattttgatc tatcgttttt ttctagataa
     9241 tgtctatata caaacaatag cacctttcta tgcttatcag ggattagatt atgttggcac
     9301 aaatatagac tattggattt cttggggagt gttaattgcc ttttcattat tgatgtcatt
     9361 gcttttgaaa tataaagaat tttttttatc taatatactg attcttttat ttttgattcg
     9421 ttttgttcca tttacttcac ttttagcatg taagtcatta gataatcgtt tgttattgat
     9481 ggaattgata tactgggggg ctattttttt gttttcgctt attttgaaac ggccttgttt
     9541 acatttttct ttctctaaaa gatataaact atctacacta agattttccg tagttgatat
     9601 tgtacttgtt ttttctgttt taattgtttt atttgtttct ggttgctatg cccattttag
     9661 attgaacttt agtttgatga atgtatatga tttaagagag gaggcacgtg attttagtat
     9721 gccagttctc ttaaagtatt tgtggtctgc tacaggaaat gtattacctg ttctttttgt
     9781 ttattatttg attataaaaa gaagaatagt atgttgtttt atagcttttg ttatcttatt
     9841 aaatttttca gtcgatggat tgaaagctaa tatctttaaa ttgtttttat gtttgctttt
     9901 acatttagtg tataaacaga atttaataaa aatgtttcct tggctttttg ctttactttg
     9961 tttcttctct ttagctgaat attatgtatt tagtactcct ctactatctg aatttgtagt
    10021 tcgtagggtc ttatatatac ctgctttgct tgattcgtat tattttgact atatatcgaa
    10081 atatggtcct gttttttatc aacgtggaga tgtacacatc gattttataa ttggagaaga
    10141 atattttggt aaagcatcaa tgagggctaa taatggtctt tttactgatg cttatatgaa
    10201 tcttggtgag ataggatgtc tcgtctatcc atttgtctat gttgcttttt ttaaattttg
    10261 tgaatcgtct tttgaaggcg taaatgtaga gttagtcatg tttgtcatta ttataatggt
    10321 tataactctc aatagttctg aatttacgac ttctttatta acgcatggtt tatttgctct
    10381 ttgtttatta ctttatttct taccaaggaa aagatatgac taaatggtcg ttttgtaata
    10441 aattgtaatt gctactatct gtgcaacatt agttagataa aatataattg ttatgaatat
    10501 tgaaaatagt agaatttatt tttttcttcg aaattccgtg ctttatggaa tgcttcagcc
    10561 tatttggcgc ttctattata gaaggtgtag aaaacgtgca atgaaattat atgcttgtga
    10621 gttattagaa aacatgaagc aaatattgga taaaaacaat attttgtttt ggcttgattt
    10681 tggaactctt ttaggtgcat atcgtgataa agactttatt tcatatgatt gtgatattga
    10741 tattgcaatt ttgtatgaag atgcagaacg tgtaaggaat ttattgaaaa attctgattt
    10801 ctgtttaact catgaatatc gtgttggaaa agcaggtgaa gtggctcagt taagttataa
    10861 atataaatct ttgtcgattg atatctgttt ttatcataag aagaatgaat ctatgtattg
    10921 ttatttatgc tctattctgc caggtgtttc aatcgtgaac aatagaagat gtgttgtagc
    10981 agttgctaaa tgtgttgttc catgtgagaa atttgcagat ataaactttc ataagttaat
    11041 atatcatgct ccatttccaa cggaagagta tttggctgct cattatggac ccaattttat
    11101 gatacctgac tctaaatttg attacacaaa ggatgctcca aacataacta attatgctat
    11161 agaagaatta gctggtgaat gtatctataa cgactaaaat atagatgaag attttacata
    11221 tatgtaatgc ttatcagaca aattctttat atcaagagtt gtttgataga attcaaaaag
    11281 ataacattga tcaagttgtt gttgctccag gatattataa atctggtagt gaatgtgtta
    11341 atggagtcca agtactgtat tattttagaa aaactggtgg ttttcaacgc ttgttctgga
    11401 agcataaagt aaatcgtata acaaaatatg ctttgtcaaa tgtaacaata tcgactgtgg
    11461 atattattca tgcgcatact ctttttagtg atggggctgt ggcttatcaa ttgtggaaaa
    11521 gacattcgat accgtatgtt gttgccgtca gaaatacaga tataaatttc tattttaagt
    11581 actttttatt ttatcgttct ttaggatata atatattaaa gcatgcaagt aaggtgtttt
    11641 tgatttcaga ttctaataaa aagaaatttt ataatatatt acctactgga atacggaaaa
    11701 atatagaaca taaaacagaa gtcttgccga atggcataaa tgattattgg ttgttgcatc
    11761 ggaattataa aacatcccat aataaaaaaa aatgcagtga aattaatttg gtatatgtag
    11821 gagattttgt taaaaataaa aatattcata tggtagtaaa ggctgttgaa tatttaaata
    11881 aa
//
