LOCUS       c00019_gnlPro..        15606 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLPDFELK_19.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:11:37
            Original ID  :: gnl|Prokka|BLPDFELK_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15606
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15606
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2647:5606]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2648..5606
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15606
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15606
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..755)
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MKQYVYLLILPIMFLISCSDDTVEEMGGSNHVLLERYPQEVINIS
                     MDNPESFASFNKTSVTRSSELLKDSVWSSGNGHTLIYETNEHIPTQGLMRYIYLGSILQ
                     GGSIEKQRFVPIVKPMDPITISYSFPARWVTDIIAKPSLSAQRQSLQNIMNKEGMTGKQ
                     LGSFTYNMRQFSYFEELKLAFGANVNIGGLLNIDVSLDKGKIRKKTGLFAKIVQRNYTV
                     DMDLPADGNILLNHDDMGSVGKYDPIYIS"
     CDS             complement(788..1627)
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MKKIFILLFVSLALFSCEKEENNKIFKYQLLPSENVSKPFSCLGE
                     KRTITFTIIQKTLIDDILDSEVPIIPKDVSIEFDKTLFSDIETKIKGDQVVLNITSNIN
                     KEDKILNVDLQISYSTINGIKVEKIPLIIDKGKLTFVYKIHSEQNPFVLPAEGGKFELP
                     FICKKQTYLNDQFIEETYSSLNGLRFKTISTGNVWFLTVRKDGEKIGFYKFTFVGEGPY
                     NQKTDPECYFNIYTHDANLITDNPTEIFRQDFIQPQTPGEDYYKPSRSSYKHGTFDF"
     CDS             2648..4876
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_3"
                     /sec_met_domain="Gly_radical (E-value: 2e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4881..5606
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.8e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQIIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(5839..7098)
                     /locus_tag="ctg19_5"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVVAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGRWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(7153..7701)
                     /locus_tag="ctg19_6"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             7889..8641
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(8746..9744)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg19_8"
                     /sec_met_domain="LysR_substrate (E-value: 1e-46, bitscore:
                     150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.2e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             9814..10287
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(10391..11389)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_10"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.3e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(11444..12712)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_11"
                     /sec_met_domain="MFS_1 (E-value: 3.6e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(12962..13975)
                     /locus_tag="ctg19_12"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(13998..15134)
                     /locus_tag="ctg19_13"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 gaactgatat aaataggatc atacttaccg acagatccca tatcatcatg atttaaaaga
       61 atatttccat cagcaggaag gtccatgtca acagtgtaat tacgttgtac tattttcgca
      121 aacaatccgg ttttctttct tatttttccc ttatcaagac tgacatcaat attaaggagc
      181 ccgcctatgt tgacatttgc tccaaaagca agttttaact cttcaaaata ggaaaattgc
      241 ctcatattat aagtaaaaga ccccaactgt ttacctgtca tgccttcttt attcattata
      301 ttctgcaaag attgcctttg tgctgaaagg ctcggttttg cgataatatc agtaacccaa
      361 cgagctggaa aagaatatga tattgtaatt ggatccatag gttttacaat aggaacaaag
      421 cgctgctttt caatagatcc accttgaaga attgaaccta aataaatata cctcattaac
      481 ccttgagttg gtatatgttc atttgtttca taaattaatg tatgtccatt tccactactc
      541 catacactat ctttcaataa ttcagaagaa cgagtaacgg aggttttatt aaatgaagca
      601 aagctttctg gattatccat tgaaatattt atcacttctt gagggtatct ctcaagaaga
      661 acatgattag agccacccat ttcttcaact gtatcatcgg aacatgaaat taaaaacata
      721 attggcaaaa tcaacaaata tacatactgt ttcataatta atataattaa ggttaatact
      781 gaatatgtta aaaatcaaaa gtaccatgtt tataagagga tcgagaaggt ttataataat
      841 cctcacccgg ggtctggggt tgtatgaaat cctgtctgaa tatttccgta ggattatctg
      901 taatcaaatt tgcatcatgg gtatatatgt taaaataaca ctctggatct gttttttggt
      961 tatatggtcc ttctcccaca aaagtgaatt tgtaaaaacc tattttttct ccgtcttttc
     1021 tgaccgtaag aaaccagaca ttaccagtac ttatcgtttt aaatctcaat ccatttaatg
     1081 atgaataagt ttcctctata aactgatcat tcaaatatgt ttgtttttta caaataaaag
     1141 gcaattcaaa tttcccacct tcagctggta gaacaaaagg attctgttcc gaatggattt
     1201 tatacacaaa tgtcaacttc cctttatcta taattagggg aattttttct acttttatac
     1261 cattaatagt agagtaagaa atctgtagat caacattcaa aattttatct tccttattaa
     1321 tatttgaggt tatatttaat acaacttgat caccctttat ttttgtctct atatcagaaa
     1381 aaagagtttt atcaaattct atcgaaacat ccttgggaat aatcggaacc tctgaatcta
     1441 aaatatcatc tatcaatgtt ttttgaataa ttgtaaaagt aatagtacgt ttctccccca
     1501 aacaactaaa tggtttagat acgttctcac ttggcagcaa ctgatattta aaaattttat
     1561 tattttcttc tttttcacag gaaaataatg ctaaggaaac gaacagaaga atgaatattt
     1621 ttttcatatt aatacaattt agttttttgc aaattaaagg atttttcctg tacaataaaa
     1681 taccaattaa ttggtatttt attacaaata accattcaat ttcattatta tgcccaaagc
     1741 atgaaaataa aagtataaca tacaagagct gtaaacaaat ccacgatcaa cacaataaaa
     1801 taaatcgttt atgcatcttt gcgatatgca tttatgcaaa atcatacaaa tttctttatc
     1861 agtaaaatac ccattaatta gtatttcatt gacaaaatga aatgtacttt aaaagcccaa
     1921 agttatattc aattcataac ctaaatgcct atccaatata aaaataatgc gtttagcacc
     1981 aagatacaaa cagaacaaca caaaatcaag ctctaaagga atgtattact attataaaag
     2041 acagaattat tcgggagatt ccctactcta aaaaagttaa agaaagaaaa tgattcaaat
     2101 aaatattagt ataacaatat caccaacaac acaatatccc cttttcaaat tatacaataa
     2161 ataatagtta aagcaactaa agacagtgca aagccaaata agtaataaaa gagcaaagta
     2221 ttaaataaag caaaaacacc caattttact ttttagggtg taaaattggg tgtcattctt
     2281 gtaaattact gattatcagc atttattgcg gagagacagg gattcgaacc ccgggtacct
     2341 cgcagtacaa cggttttcaa gaccgccgca atcgaccact ctgccacctc tccagaacta
     2401 cggttaagta gtgcttttct cttaaagcgc tgcaaaggta cgaatcattt tttaacttgc
     2461 aaattattcc gcaaaaaaat attagaaaag tatatttgaa agtaataacc gccctctggc
     2521 ttctccccat aaataggtat ttttatgcta ttcaacataa aataggaccc ttttatatac
     2581 ctaaaccgaa aaaaggttgt aaatttgcgc gctctaaagg ataactaacc actaactgat
     2641 taattttatg gaactgaata agacctttaa agatggactt tggagcaaag aaatcaatgt
     2701 aagggatttc gttagtaaca acatcactcc ttatgaaggg gatgcttctt tcctgcaagg
     2761 acctaccgaa cgcaccaaag ctgtctggaa tcactgtctc aaagctctcg aagaagagag
     2821 aaacaataat ggtattcgtg cactcgacta cacaactgta tctactataa cctctcaccc
     2881 tgccggctac atcgataaag aaaacgaact gatcgtcgga ctacagaccg atcaggtgtt
     2941 aaaacgtgcc atcaaaccgt ttggcggaat caatgtggtt atgaaagctt gccgtgaaaa
     3001 cggagtggaa gtagatgaca gagttaagga tatcttcact cactatcgca agactcacaa
     3061 tgatggggta ttcgatgtgt ataccgaaga aattcgttcg ttccgttcat tgggattcct
     3121 taccggactt cccgacaact atgcacgcgg acgtatcatc ggtgattatc gccgcctggc
     3181 tctctatggt cttgaccgtc tgatagaagc taaaaaagaa gatctgcata atctgacagg
     3241 tcctatgact gaagcccgca ttcgtcttcg tgaagaagta gccgagcaaa tcaaggccct
     3301 gaaagagatt aaagtattgg gcgaatatta tggtttggat ctgagccgac cggcatatac
     3361 cgcacaggaa gctgtacaat gggtgtatat ggcttatctg gctgccgtaa aagagcagga
     3421 tggtgctgcc atgtcactgg gtaatgtatc ttcattcctc gacatctatc ttgaatatga
     3481 attaagccag ggtacgataa ccgaaacatt cgctcaggaa ctgatcgacc aattcgttat
     3541 caaactccgt atggtacgcc acttgcgtat gcagtcgtac aacgatattt ttgcgggtga
     3601 tcccacatgg gtgaccgaat ctatcggtgg acgtttcaat gacggacgta ccaaagttac
     3661 taaaacttct ttccgcttct tgcagacact ttataactta ggcccgtcac cggaacctaa
     3721 catgactgta ctatggagcc ctgagttacc cgaaggcttc aaagcattct gtgcacaagt
     3781 atctatcgac acttcttccg tacaatacga aaacgacgac ctgatgcgtg aagtccgtca
     3841 atcggatgac tacggaatcg cttgttgtgt ttcatatcag gaaatcggaa agcagattca
     3901 gttcttcggc gcacgtgcca accttgccaa agccctgcta ctggctatca acggaggacg
     3961 ttgcgaaaat acaggtacag ttatggtaaa agacatccct gtattgaccg gtgaaacact
     4021 gaagttcgaa gaagtaatgg ccaactataa gaaagtattg atacaaattg cacgtgtata
     4081 caacgaagca atgaatatca tacattacat gcacgataag tattactacg aaaaggcgca
     4141 gatggctttc gtggatactg atccccgcat taacctcgct tatggtgtag ccggactttc
     4201 aatcgccatc gattcactgt ccgccatcaa atatgcacat gtgaaagccc gtcgcaacga
     4261 catcggactg acggagggat tcgatatcga aggtgctttc ccttgtttcg gtaatgacga
     4321 tgaccgtgta gaccacctgg gtgtagacct ggtatatttc tttagcgaag aattaaagaa
     4381 actccccgta tataagaatg cccgtcctac cctctcgctg ctgactatca cttcgaacgt
     4441 aatgtatggc aagaagaccg gtgccactcc tgacggacgc gccaaaggca ttgcctttgc
     4501 tcccggtgcc aaccccatgc acggacgtga taaaaatggt gcaatcgcct cactgagttc
     4561 tgtagccaag ttgcgttatc gcgactcaca ggatggtatc agcaatacat tctcaatcgt
     4621 tcccaaatca ttgggagcaa cacaagaaga ccgtatcgac aatctggtga ccatgatgga
     4681 cggatatttt acaaaaggcg cacaccacct gaacgtaaac gtgctgaacc gggaaatgtt
     4741 gcaggatgcg atggaacatc ccgaaaagta tccgcaactg actatccgtg tctcaggata
     4801 tgccgttaat ttcgtgaaat tgagccgcga acatcagttg gaagtaatca gccgcagttt
     4861 ccacgaaaga atgtaattga atgataaacg tacactcata cgagtcaatg ggaacattcg
     4921 acgggccggg tctccggctc gtcgttttcc ttcaagggtg taacttccgt tgcctctatt
     4981 gtgccaatcc ggacacaatt gaagccaaag gagggacagc aaccgaccct gaggaaatag
     5041 ttcgcatggc cgtcagtcag aaagctttct tcggtaaaaa gggaggtatc accttttccg
     5101 gcggagagcc tacttttcaa gcaaaatcgc ttatcccact ttttaaaaga ctaaaggaag
     5161 caggaatcca tatttgcctt gataccaatg gcgggctatg gaacaatgat gtagaggaac
     5221 tattggaatt gactgatctg gttttattag atatcaaaga atttaatccg gaacatcatc
     5281 agtctttaac cggaagaagc aacgagcaga ccctgaaaac cgcagcctgg cttgaaacca
     5341 atcataaacc attctggttg cgatacgtat tagtgcccgg ctacagtgac ttcgaagacg
     5401 atatccggca gctgggagag catcttggaa cgtaccagat tattcagcgt gtagaaatat
     5461 tgccttacca caccttgggt gttcacaaat atgaagcaat gaacaaagaa tatatgctga
     5521 aaggagtgaa agagaatact ccggagcaga tagaaaaggc tgagaaacta ttcaggcaat
     5581 atttccggac cgtacaagtg aattgactta tataagtgtc gaaattcgta ttcgccacag
     5641 attacacgaa tttacacaga taaagattca ttggcaatca acagattaag ttcattctgc
     5701 ggtgaattat gacgactgca cttatttata attttgtaag tcacgatata aaagtctccc
     5761 tgttcttgcc ttaattcatt acaatacaag gcaagaacag ggagataatg taaccggcat
     5821 attttttgcc atcctacttt aataagtgaa tcgcaatcct gcctgcaagt taaagttaca
     5881 aggcctttct tttcggatgg tttgtacttt ggagccatca tcaaagaaat acgaaactcc
     5941 cggttccaca tataggccga catgatctgt cgcattgaat tgcgctccca cggcaccggc
     6001 tacagaaaat tgcaaaggct tcacattcac cttatcatcc gccaactttc cataaacaca
     6061 cttttcaacc attcctccgg cagatacata gagtgtaaaa tatttctttt ccagaaaatt
     6121 ccagtttcca cgtacaggaa tacctatata atgcaatttc tgactctgca tcttggtatc
     6181 cccctgccgt ttgatgtcag aagacaacaa cgtataagtc aatcccgtct ctacagagaa
     6241 acctttggga agagacttac gtacagacag tccgaagcta accggctgat gatgttcata
     6301 atccaccacg gcagttgtat tggacttcag gtaagggacc ccttcttcaa atataacttc
     6361 ctgatcggca ggaatactca cagctccatt catgatcgtc atcaagtcga ccctgttagt
     6421 catcggacgg ggcgcaaaat tttcggaacc atttgtcgga agtccacctc cattaccgat
     6481 acccactccc atcgaccatc taccaccacg tttagcagaa gagtctccga taggcaactg
     6541 atacttgtct ttaccggacg gtcgccgcgc ttctttcctc tttggaggct gcgctgtcgc
     6601 actttctttt ttctcgattg cagcagttgc ttcctgttgc ggctcagctc tcttttcctc
     6661 cgtcactgcc tccggtcgct tctctgccaa ggaggatacc tccggaacaa tcaccggatc
     6721 agtattcttt gccaaatagc ccgaaacagg gttgatactc gtcgttccta ccggcttaac
     6781 gggttcggat acagctacct gtacatccgg caaggcaggt tccggcaata catccgggtt
     6841 gacagccagt gaaggagccg ttgcataacg gatttcatca gctaccggac tattcagaaa
     6901 atacaaactg acagcagtcg ttaccaccaa taccacagct gccgcaacaa ccgcccaccg
     6961 gcgatacgga tatattcgtt tttcggttac aggcatcagt tccctttcca gtcgttccca
     7021 accggaagca ggcatcggct ccgaataatc ttcgagctta tccttgaatg ctttaatcca
     7081 tttttcgtct tctttcatca ttctatttca tttttgaaat ccaaggttca cctcagtatc
     7141 tgtaaataca tgtcaaccat tggtcaccaa ccattctttc actttctttg ccaatacact
     7201 ttttgcgcga aaaagctgtg aggcagaaga tttttcatta atccccaaca tctgtgcgat
     7261 ttccttgtgc gacttatctt caaaggtgta taaattgaat acggtacgat atccggcagg
     7321 gagttcatta ataaattgca tcagcacttt ctgtggtatt gcttcaacag ccgaagcatc
     7381 cggttcttca tacgtttcgg gaacttcatc cagtgccgtg gtctggttca tcacgtcgtt
     7441 ctttcttaag aactgtaaag ccgtattcac cattacacgc tccatccatg ctctcagaga
     7501 gccttcaccc cgccaggtaa acttgtcgaa ggagtcgaaa atcttcagga aaccgtcgtg
     7561 taccaagtct tgtgccatgt ccctgtctcc ggcataacga agacagacac caagcatgcg
     7621 ccctgcgtac tgctcataaa gttctttgcg ggcacgatta tctccctgcc tgcaacgttc
     7681 cgacagctct aattcattca ttctcctaaa cacgtgttta ccttataaat gcagcaaaga
     7741 tagaaatact gcacagagag aacaactctt ttatcacttt tgtttcttta acattttagg
     7801 atgcaatatt tcatcacttc ctgcattttc tcaatacaat aaagaataaa tctcaatgga
     7861 taaataggat aaaaccaaca agaaacttat gaagaaattt aatttaataa cttttgccgt
     7921 catcctgatg ttattgccca tattacagtc atgtctggac gatgccaaca acgacgagtg
     7981 ggtcacttgt cctccgggtg gaatattagc catcggcaca atgaagattc ccaatgcgga
     8041 cactccaagg gactttttca ttgcgttgga caatggagac aatgtacttc cggcagatac
     8101 ggccgatata cgcaacagga aatacactgt tgcagaaggt caaagagtct tcgttggcta
     8161 tctgcagatg ggaaaagaga agcccggata tgagaacggt aaaatattca cgatagaaga
     8221 tatattgacg aaagagatca ttccactgac ggaagctaca gcagacagca ttggagacga
     8281 ccgtatcaac gtcacagcgc atgcacttac gaaagattat ctgaccatcg aatatcaata
     8341 tctgggcagc atgaatgaaa ataaaaaaca catgctgaac ttggtacaaa acgaaataac
     8401 aggtcccata aaagatgacg gatatatcta tctggagttc cggcataatg cctttaatga
     8461 ctcccccaat caattgggtt cgagccttgt ttctttcaag ctggatagta tagccgagca
     8521 attggcgaca gccaaaggaa taaaactccg tgtgaacacc atttatgaca atatacagta
     8581 tgtcacaata gatatcaacg aagacaaaaa cttaaaaata aaatcatttc attctcaata
     8641 aaacaacaag aaacacctac acaatcaggc aaaacgagta ataattctga tacataaaag
     8701 aaataaggcg gcgatgtttg tgaaaatatc gccgtcgttt ttatattata ccaaacactg
     8761 aacggcctgc agggtaagca tctccttggg aaccgccgcc tgaatctcct ctttcaaaac
     8821 ctgcagcaga ctggtgcgga tgaagtcttt ccgggtcacc aggacaatct gacgggtagg
     8881 ccgcgggata gcaaacggac ggaccagttc tttctgctct tcgctcaatt gcatcactgc
     8941 cagttcggga ataaacgtaa tccccttacc actctccacc atatgcataa aggtttccat
     9001 actacccagc cgatacgcca tttggctgat cttaaccgct tccatctgac aaaaacgaac
     9061 caactgatcg cggaagcaat gcccttcgtc aagaagccaa agccgttccc ctgtcacatc
     9121 ggacgtacga atcacatcgt gcttgaacaa cggttccttc tttgagacat agcccaggaa
     9181 ttgctcgtag aataaggtct cttccgttaa tgcggcatca tccagcatgc tggcaatgat
     9241 agcagcatcc gcttcaccgg tcagcagagc cttgcgaatg tcgggcgtct tcatctccat
     9301 cacccgtata tcaagatccg ggtatttctc catcagttgc ggaaagaaac ggggcagaag
     9361 ataaggtgca atcgtcggta acactgccaa tcggaatgta cccgacaggg agtgctgttc
     9421 ttcgctgatg atctccttga cacagataac ttccgaaaga atcttacggg cctgttccag
     9481 cactttctta ccaatggcag tagggcaaac cggtgtcatg ctacggtcga acagtttcac
     9541 ccccaattcg tcttccagct tctggatcat tgcactcaaa gtaggttgcg tcacccggca
     9601 atactcggca gctttagcaa aatgccggaa ctggtcgaca gccagaatat attccaattg
     9661 ttgtatagtc atcgttctct gatttattaa agatatagaa tctatcaatg caaagataga
     9721 aattttcagt ttgacacgaa tcattttgtg ccgtatcttt gttccagata aaaagaagaa
     9781 atatagtatt aactcaaaaa aaacaatatc attatgaaga ctttaaatta tacacatttg
     9841 gaagaaaaag gagctaacac catcgtactg tcattacagc aactgcttgc cgattttcag
     9901 attcattatg caaacctgag aggatttcac tggaacatca aaggacacgg tttcttcgta
     9961 ctgcacagca agtttgaaga tttatataac ggagccgccg aaaaggtgga cgaaatagcc
    10021 gaacgtatac tgatgctggg aggaactccc gccaataaat acagtgacta tctgaagatg
    10081 gcgcagatca aggaagtgga cggagtgaat aaggccgacg acgctctgaa tcatattctc
    10141 gaaacttacg ggcatctgat tgcggaagaa cgtaaaatcc tgtctctcgc ctcttcacac
    10201 aacgacgaag taacagtggc catgatgagc gactacctga aagaacagga aaagatggtt
    10261 tggatgctga ctgcatacaa cggataacag ccgaaagggt gtagccatct gaccgaaaag
    10321 gtgtagccat acaaacaaaa gggtgtagcc atcccggcag gatagctaca ccctttctgt
    10381 tttattcgat tcagatgata cttgtacgtt tggtaaattc aataatctcc ggaatgtatc
    10441 cgaatgcgag cccggtcact gtatccgcac acccataata gatggcaatc cgtccggtct
    10501 ccgaatcatg aagcgccgcg catgggaaac agacattagg cacatcaccc atacattcgt
    10561 aatccttctg aggtgaaatc agataaggcc ccgaacggaa ttttactttc cagggttgat
    10621 cgatgtcaag cagtgccgaa ccaaaactat acacaaaacc gttgcaggaa gccaatacac
    10681 catgatagat cagtaaccag ccttccgagg tttcaatcgg gataggccct gcaccgatct
    10741 tggtacactg ccaggcactg tcttcgaacg gagccggcga cataacatga cgatgacgtc
    10801 cccaaaactc catatcggga gactcgctat agaaaatatc tccaaaagga gtatgcccat
    10861 tatcactcgg gcggctcaac atcgcaaaac gaccgtttat cttacgaggg aacaagactc
    10921 cattccgatt gaagggaata aaggcattct ccaactggtg aaaagtaaca aaatcatagg
    10981 tgtaggccac accgatagta ggaccatgat agccattaca ccaggtcaca tagtagcggt
    11041 cttcgataaa gcaaacccgt gggtcatatc catagaccca ggttccaacc tcagcgtcat
    11101 cacattgaaa ctttaacggt tcttcgttga tatcccaatg aacagcatcc ttgctgaatc
    11161 ccacatgcaa acgcatgcga cgattagtat catcacaacg gaacacccct gcatagccat
    11221 ccttaaacgg aactacggca ctgttgaata tactgtttga agtagggagc aagtcgcgcg
    11281 gaataatcgg attggccgaa caacgccaca ctacatcttt acatcctgcc ggacgttctt
    11341 cccaaggcat agccggcaaa gcagcacctg caattttaat ttcttccatg attcgattaa
    11401 attaatatta tgtatatatc ttgtttatat tgaaaatctc tttttatttc ttctttccgt
    11461 ccggatatgt gaaaggtacc agccaagtca cgataaaagc cggtatggta gcgataagta
    11521 cccagataaa gaaatcgcga taacccagcc aatcgctcag gtatccgctc atcattccgg
    11581 gaagcatcac ccccagattc ataataccgg tagcaaaagc ataatgtgcc atctgatgtt
    11641 tgccgggagc cacttgctgc atcataaaga gcatcaatcc gacaaaacca aacccgtaac
    11701 ccaagtattc agacacaatg gccataccaa taatccatag atcggaaggc tggtaaaggg
    11761 ctaacaggaa atataccaag aacggaatat taaaagcgca acataaagaa aacaaagtct
    11821 tccgaagtcc gaaagccgaa atgtaataac cggccaaaag cgaaccgaga ataaaagctc
    11881 ccgctccgaa cgtaccatat accagtccga tatcctgagt gctgagtccc aatccaccat
    11941 ccgcaaccga cgctttcagg aacaacggta caatcttgat ggcatatcct tcggcaaacc
    12001 ggtacaaaat gataaagaca atgtagaaag caatatgttt tttttggaaa aaagagcgga
    12061 tgacttccca aagcatattc aatgcgtcac tcatcgtatt cacttcaccg gaagctcctc
    12121 ctcccgaagg caaaatccgg atgtggtaaa gaccgatcag aatcataata cccgcacaca
    12181 tcaacatgac aatcatccag gcatgtacca ctccaaattc atccttcagc atacctgcca
    12241 gccaaaccaa gcctccgttg gcaagtatct tggccagatt ataaaaagct ccctgccaac
    12301 cgatatactt ggcttgctgg gtagcagtca gttcagtcag gtatactccg tcacccgcaa
    12361 tgtcatgagt cgcaccactg agagcaatga tccccatcag agcgatggca taacgaaaaa
    12421 agtcgggcag cggcagcgaa agtgctacca atgcaaatgc cagtccggta atgatttccg
    12481 tagcgacaac aaagtatttt ttcgttttaa acatttccag aaacggactc cataaaggct
    12541 tcaatgtcca gggaagcata atgagagagg tccagaaagc aatctgtgca ttcgacactt
    12601 ccatatcgga aaacataagg acagaaacca tcgaaagggc cacaaacggc aatcccatag
    12661 caaagtaaac agtaggcacc caacatacag ggcttatcgg ctttttattc atcagttagt
    12721 tttttataat aattccatcg gttaacaatt ccagtaagca aagatagggg atattaaaaa
    12781 cataacccaa gattacgaca agaagttgct ttcattattt aataatacaa ctcacccggg
    12841 aaaactacta acctctatca cccttttttt attaaacttt atcaatacga cacacgcaaa
    12901 gaagcaccga agactttcat ccccgatgcc tctcgccccc ttatctacaa tctaaacacc
    12961 tctattgctt cacatataaa tttatctcag caaacccggt ataattatcc ggagtcagac
    13021 agtttattct gaattccttt acattcggga taggtggttc gatggccgca tattgcggat
    13081 cagccccttt aaaatttctg aaagtcaaga ctctcgggta agtaacccac tcggtttcac
    13141 cctctttccg aaccttaatc tcagcacttc tcagattata acccgatccg taggcactct
    13201 gtttagtgac cgaaaatccg gttaaggtaa caggccggtc cagtaccgta ttccaccaac
    13261 actctccggc attagccact ccccatgtaa accaagtagt atttatctca ccgtcaatag
    13321 ccagatgtgc accatatttg gcatcatcat cggcataaac attactgcaa cttacactcc
    13381 acgcacttcg atctacagcg gaccaattcc cgggtttcgt ataactggta taaagcacgc
    13441 tggtataaat ccggatataa accgtcttca tagatgtact gacagcctgt tcgtccatgc
    13501 ccgtaactcc tttaagcgtc acgggaagca catatccgtc aggattagtc aacttttcta
    13561 tattcttcaa aacgacctga aaagatgaat cggccactgt ctgtcccgtt tttaagacaa
    13621 cttcacttgt ttcaatggta taattatctt ggggcaacaa cttacatttc gtcttattgg
    13681 cagaattgta agtatccact ttcagcgtat ctactcccaa agcggcagtg acatcccgcg
    13741 taaccggctg tacggcacac aattgtattt caaaatcaga acggtcggca gtagaggaat
    13801 tgctcacaca atccaccact accgcagcac ccatttcggc ccccggtgca actcccgttc
    13861 tgatatatat cttttgatat ttgtccattt catcatcatc gttgctgcac gaagccaacg
    13921 atacaaagcc tgttatcagg cagattaagg tcacaaaatt caaatgtcta ttcatatctt
    13981 atcttctttt tacatagtta ttgcttatca aaacgaacat gctctttcca gacaagagtt
    14041 cctcctgcca ccaaatcgta tccgtgtccg gtacagtcgg caaaggcatt tcctttacct
    14101 tcatccattt tccaatagcc tatcaggttc ggatcggcgg gtttcacggc aaaatacatg
    14161 ttggactgaa tttgcgtctg gctgattgcg ctcttccaaa gacgcacctg ggccatctga
    14221 caattgttgc ggaagtagct accgctcgaa accatgttca tcttgtcgaa tctaaccggg
    14281 ccaccctttg tctgcagagt cacgtcgagc actccgttga tataaatcga caataacccg
    14341 gaagaattat aaacgaaggc cagatgatac cacttattct tctcaaacaa agtcaccgta
    14401 ttgacctgac ttccaagtgt cttcacctgt aatgaattat aagggatcat agcgtcaccg
    14461 aaacggatat aaacctcgtg gtcgctgctg cccgaattaa atatagcctg attattaata
    14521 tcgaatccgt ccatctgtac ccaagcctcg agtgaccatt cattggttgt cactccccac
    14581 aattcgtcct tggcgggctt cacggcattg gtcgtattca taaacggtac agactgtatc
    14641 agcggcttat ccagcaaaat gataaacttc gacgaaagcc cgattgtgga caccggtccc
    14701 tgaatttctg tgagagatac cggaatagca tacaattctc cgttttcgtt tgaataaggt
    14761 ttcactctaa actcactggg gattgcgcta acatcgcctg ccgctatctt tatctctttg
    14821 tcataagtaa aatactgctc gggaaggact tcgtacgaag tttcattagc ttcattgtac
    14881 tctttaagaa tagaaggatc taccgtcagg acagcagtca cattttcggt tacaggctgt
    14941 cccacacgta cggtcagagt agttgttgtt acattttcag gatcaacggt aacctttgcc
    15001 gaaccattct cggatgcttc attcaaataa atcgcattgt cgataacctg gtaatcggca
    15061 tcgttgcatc ctgccaggat catcggcaga acgaaacagg caagcaaata ttgttttatt
    15121 gttattcttt tcataatcaa attctttaaa gtcattttac agcaggattc attattctga
    15181 ttgcttcacg caggtattta tattcgatgt cgcccggata gtcatattcc atgtgatagg
    15241 tgcctactcc acccttccgt acctgttttc cgtcaatagt cggagtccag cgtgccatgc
    15301 cggcaagtgc tctcattttg tttccgtaac gatctacata atcacctcct cctgtcggag
    15361 cataagattc gaaattctcc gtaacgatgt acatattagc cactttctcc ggaggaagta
    15421 ttcctttaaa gttggcaatc gtaccagcca gacgtctgtc aagattagca tcggaattac
    15481 ccgcaaggtt agagtatgcc tgcacaatga aatagtcaaa gtaaggcccg gtttccggat
    15541 gaatactttg aggctcgcca tcaatcacaa gtaaccgtcc cgtacccgat ttaggtccga
    15601 ttcttt
//
