LOCUS       c00080_gnlPro..        24125 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKHOGCEA_80.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:27:36
            Original ID  :: gnl|Prokka|NKHOGCEA_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 69816
            Orig. end    :: 93941
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24125
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[79816:84455]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24125
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24125
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             239..1753
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.7; E-value:
                     2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_51"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-82, bitscore:
                     268.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1768..2010
                     /locus_tag="ctg80_52"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRNILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2014..3396
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_53"
                     /sec_met_domain="MBOAT (E-value: 8.2e-22, bitscore: 70.2,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRYNLPQYI
                     GKYAVDSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3415..4455
                     /locus_tag="ctg80_54"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFVIGPDYY
                     QKKASREDIKILKAILGNSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4560..4952
                     /locus_tag="ctg80_55"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5145..5777)
                     /locus_tag="ctg80_56"
                     /transl_table=11
                     /translation="MMLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGV
                     DYVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKAL
                     GKPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVD
                     HYQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5758..6279)
                     /locus_tag="ctg80_57"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKYGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6300..7091)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_58"
                     /sec_met_domain="F420_oxidored (E-value: 1.2e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSVEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7088..7420)
                     /locus_tag="ctg80_59"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7423..7920)
                     /locus_tag="ctg80_60"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8126..8668)
                     /locus_tag="ctg80_61"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8786..9769
                     /locus_tag="ctg80_62"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLTAETDKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_63"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.6e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_64"
                     /sec_met_domain="CT_Btheta (E-value: 1.5e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_65"
                     /sec_met_domain="OAD_gamma (E-value: 9.3e-16, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_66"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.8e-22, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_67"
                     /sec_met_domain="OAD_beta (E-value: 2.9e-153, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14787..16118
                     /locus_tag="ctg80_68"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16132..17424
                     /locus_tag="ctg80_69"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKKYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEEIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIEDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17906..19756
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_70"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-62, bitscore:
                     204.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASISVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLIPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRDIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19914..20354
                     /locus_tag="ctg80_71"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGTEMEASRITECIEDLKRLHEVLNEI"
     CDS             20367..21434
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_72"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.6e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21439..23034
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_73"
                     /sec_met_domain="MFS_1 (E-value: 4.7e-14, bitscore: 44.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAQTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23129..24124)
                     /locus_tag="ctg80_74"
                     /transl_table=11
                     /translation="YKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETK
                     SPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKSCID
                     SGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTE
                     PDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGVMKE
                     LPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRL
                     AMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 agtatcaata aagtatcgtg ttgtctatcc cattcaaagt cgtcggctat gaagccaacg
       61 ctatttcccc ttccgaaaga gggaaagcga gaccgggcac gtgcgtacca cacaattaac
      121 attctttaat cgattgtgcg tagggagatc agaccatttc actgtcatct taataaacga
      181 tctcaagaag atatataaag aacccctaaa cccaaaacat gaataaaaac taatggatat
      241 gacaacatct tcccagaagg atattatcaa tgatattctt tccgccatgc aatgttatcc
      301 cgaaaacgaa gcattcatta ttgacgataa acattatact tatgcccaac tcggtgaaat
      361 aacagcttct atcacccatt cgctatcaga aataaaagat gaaaaaatcg gaatcgtagc
      421 ggaaaaccgg attgaaacct atgctgctat tctggcagta ctagccggcg gaaagaccta
      481 tgttatcctg catcctgcct acccggaaga gcgtaatctc aaaatagccg ctctggccgg
      541 actgcgtact ttgctctgta caagtgacac tgaccggtca gcattcggca ccggacactt
      601 cagaatcatc gatacggacc ggctaccggg aaaaacactg tcagaacagc agtcccattc
      661 atcggacgaa gaaaggaacg cttatatcat ttttacatcg ggaagcacag gcgagcccaa
      721 aggagtgccc atcacacggg ctaacttgaa cgccttttac cgggcataca gttcgctcga
      781 ctggaatctg gatgaacatg atcgcatgtt gcaaatgttc gaacttacat tcgatgtatc
      841 cgtagtatct ttactgtatc ctcttacttt aggtgctgcc gtttatacgg taggccatca
      901 ggatgtaaag cacttcaagg tgtttgaact tctggagaag tatcaactga cctttgccac
      961 tgtcactccc tcactgctac aactcctttc accctacttc gacgaaatca atctgccctc
     1021 tctgaaatat ctgggagtat cggcagaagc atcgcaaacc gagctgttgg agcgattcag
     1081 aaaatcggca cccaacgcaa cgttcatcaa cctatacgga ccgaccgaag ctacgattta
     1141 ctgcacctgt taccgtattc cggcttcgga caaatgcaag cattacaacg gaatggtggc
     1201 tatcggaaaa ccatttcccg gcatccgcgc catcattgcc gacgaagaag gaaacgagct
     1261 acctcaagga gagacgggag aactttgggt atccggccgg caggtaatga aaggttatct
     1321 ggacgacccg gaaaaatcgg cattggttct gatacaccgt cccgacggac aaatctatta
     1381 ccggaccgga gacttgtgta ttctggatgg cgacggggat attatttatt gcggacgtaa
     1441 agactatcag gtgaaaatac agggtttcag gatagaactg agtgaaatag aatatactgc
     1501 ccagtcgttt ttcaagactc cctgcagcgt ggctgccgtt ccgttgctct gcgacggaat
     1561 ctgtaacgaa ttgcacctgg ccgtcgagac aactgaatgt actcaaagcg cattgataga
     1621 atatctgaaa gaaaaactgc ccaaatacat gctgccgaag cagattcatt gtatttccca
     1681 atttccggtg accaatagta ataaaacaga ccgtaaaaag attgccgaac tgataaaaga
     1741 gaagaaactc taaaaacaat aataaatatg aatcgagaag aagtattaaa acaactacaa
     1801 agcattttcc gtaatatctt aaaaaaggac aacgtatgta tcgacgaatc atctacctca
     1861 aaagatgtag atggctggga ctcgctaacc cacatgcaaa ttatagctca aatcgagaaa
     1921 catttcggag tacgtttcaa tttcagggag gtcattaagt tcaagaatgt cggcgatttg
     1981 tgcagtgcct tattaaccaa aatggaataa acgatgcagt tcctctcttt tagtttcctg
     2041 gccctgttta ccctctgttt cttcctctac tatgcagtca aaggccgtgc ccgcaacctc
     2101 atactactgg taaccagttg tattttcatc ggatggtact atctgccttt cctgttgacg
     2161 gcagtagtgg tagcactgtt caccttcttt tgggcacaat ggatggaaag cagggcaaaa
     2221 gccggaaaaa agaccaaacc cgtctatatc gcaggaatca tcgccctgat cggcggatgg
     2281 ctccttcttc atggcacggt catagatgat atcatctttc cacttgggat gtcattttac
     2341 acatttcaag ccatcagtta tctgacagac gtgtactggc aagagcaacg cagcgaaaga
     2401 aactgggtgg atttcctgat ctatatgctt ttcttcatga agtttctctc cggccctatc
     2461 gaacggggtg gagacctgtt gccacaattg aaagatcccc gcccgttcat ctactcaaac
     2521 gcggtgaccg gactgaaata tattttactc ggactgatca agaaactgct gatagccaat
     2581 cagatctccc cacaaacaga tgtcatgttt cattcgattc atgacctctc gggtgtacaa
     2641 ctgctaatga cttgcctact ctaccctatc gaactgtatg ccgatttttc gggttatacg
     2701 gatattgcta tcggaggggc ctatatgttc ggcatcaagt tgtctcctaa cttcaaccgc
     2761 ccgtttgcag cacgctcgac tgccgacttc tggcgccgtt ggcacatgtc actctccttc
     2821 tgggtacgcg attatctcta tgtaccgcta accgccggta cccgtaactg gggacagtgg
     2881 ggaatctact tcagcctcct catcaccttt ctcgcattgg gtttgtggca tggggccgga
     2941 ttgactttcg ccatatacgg cctgattcag ggtgtcctta tctgctggga aatgaaaaca
     3001 gctgctttcc gctataatct gccccaatat ataggaaaat atgcggtcga cagcttgctg
     3061 attgtccgga cttatctatt gttcgcactc tcgcttatat tctttcgtgt acaatcgctg
     3121 agcgatgcct ggtatttctt acggaacatc tcgttcgagg tacattcttc ctggaaagaa
     3181 atgaacatcg gcatacgcga tcataattgc atcgtagcag gttcggccct attactagta
     3241 ttgatctacg aatattatgc atctaagtac aacctgatgg aaacacttga acgccaaccc
     3301 gcatggttac ggtggagtgt ctactatctg ttggtattcg ctctgctgat gttaggcaaa
     3361 tttgacacgg aaactttcat ctatttacaa ttttaaccga aaccctttac gcgcatgcta
     3421 catcattcat cgagaatctc ccccaagaca cgtttttgcc tgaagttgct tttactgatc
     3481 ctgccgctga tcccgatagt ggttgtctat tttatgtttg atccttatag ggtattacac
     3541 ccctacaaac gattcgacga ctctcccatg ctactcaacg aagcccatgt gggatggcag
     3601 aattatctgc agaatcgcga ttcgatagcc tataactcct ttatactcgg taactcctgt
     3661 accatggcat tcctgacagg agaatgggaa aaatacctgg ataagaacga ccatgccgta
     3721 cgcttctatg acaacggaga aagcctgggc ggcgtccgtc aaaagcttca gctgctcgac
     3781 tctgtaggtg cacccctgaa aaatatactg atcgttctgg ataaaaaatc actggacaaa
     3841 aacgctcctt tatcgggcaa caatcatctg ttttcggccg aagcagccgg catcagccaa
     3901 ttgggattcc agttgagatt cctgcaggag ttcctttatc cggacagaat gattccttac
     3961 atagattatc tgatccgaca taagtatgct ccttatatga aaggggttat aaatccggga
     4021 gatcccgtca gggagcctta cacgaacaat tttatcaatc ccagagaaaa agagatcgcg
     4081 caagatggcg aaatatactg gagccgtcat gaaaaagaat tcaagaagcg aacgaatgcg
     4141 ggtatggaag aacttcctgt tatatttgcc agccagattc aggtacttcg ctccatcaaa
     4201 aaaatctgtg ataagcacca cacgaacctg aagttcgtca tcggtccgga ttactatcag
     4261 aaaaaagcca gccgggaaga cataaaaata ttgaaggcta tactgggtaa ttccgctgtc
     4321 tgggatttca cgggaatcaa cgaatacaca gccgacatac atcattatta cgaacccggt
     4381 cattatcgtc cgctgctggg agcacgctta ctgaaagcca tttatcagga tcaagacacc
     4441 tgccacaggc aataaaagtt cctcccataa cagtagcaca cacagaagaa gagcatcctc
     4501 gatccgaaag aaataattat atcaaagaaa acaattatat cacattaaaa acttagatta
     4561 tgaaaaagat tttattattg ctatccgtct gtatttcatt ttcatcatgc tgtacattat
     4621 tcagcagttc caaacaagat atcaccttta cgggaatgaa tggaaccaaa atctacgaag
     4681 catcgaccaa acagaaaata gcggaaatca aagaagacaa tagtgtcact gtacaaatca
     4741 aaaagaaaag ggaagacaaa caactagtag ccaaaaagga agggtaccaa acgactccct
     4801 ttgtcctgga atctacattt aacaatgcct gcctgtggaa cattctattt tggccgggct
     4861 ttctggtaga tttgggtacg caaaagatga acaaatggga taacacaatt atcaatatcg
     4921 aaatggagaa agaaaataca gaaaacaaat gatcaaacta taatttcgca tggcactctt
     4981 ctccttccac ggagggagtc gccatacgga atcatgcgac ctacaaggaa ggcataattc
     5041 accacaagtc aacacagagt tttttataaa agttctttag agaataaatc tactctgtga
     5101 gactctgtgc tactccgttg tatatacgag tttcggcaca ctctctatag ttgtttcaat
     5161 tccctgtata atttctgaat gggaagtccc attacattga agtagctgcc ggatatggat
     5221 tctactccga caaaaccgat ccactcctgc acaccatacg aaccggcttt gtccatgggc
     5281 tgatagtgat cgacataata agcgatttca tcttcatcaa gaatcgcaaa acggacatcc
     5341 gtcacggcag cgaaacattt ttgccattct cgggtagtga gacacacacc ggtaatcact
     5401 tggtgcgatt taccggagag gctccgcaac atctctatgg catcctgcct tccaacaggt
     5461 ttgccgagcg ctttgccttc atgccagaca atggtatcgg ctgtgatcaa aagctcttcc
     5521 ggtccgatca tcgactgata ggcggctgcc ttctcacggg ctatgaaaag aggaatctct
     5581 tcaccttgca acgtatcggg ataagattcg tccacatccg gcaaagtttt tactacataa
     5641 tcgacaccca agcccgtcat cagttctttg cgacgcggag aattagaggc caatacgatt
     5701 ttataacgat ctaagttagc aagcatactg ataaataaat aaggtatata ctggaaatca
     5761 ccatccgaaa gcatcatcgg acaaccattg gccttgtgct ttaagcacct gctccaccac
     5821 atcgcgtcca cagccgtatc ctccatcggc atacgaaatg taacgggcaa tcgctttcac
     5881 ctcgggaacc gcatctttgg gacagcaggg caatccgcac tcacgcatca cttccatatc
     5941 gggaacgtca tcgcccatgt agagtatctc ctcgtccgta agtccgtatt tgtcacggaa
     6001 accacgataa tcgtgtatct tcaccgcaga gccgaagtac agatcggata cccccaaccc
     6061 tataaaacgt ttccgcacga catcgctccg cccacctgta ataatagcga tacgaagccc
     6121 tttttttacg gccaattgga tggcataacc gtcttttaca tttaccgtac gcatcggttc
     6181 acccgacgga tgcaaaggga tgacattggc gctcagcact ccgtctacat cgaaagcaag
     6241 tgcctttatc cgggtaaggt cgtaattgat tgtgctcatt tttatttaat gtttcgggat
     6301 tattgtcttt cgtgaatgct tcggctaagc aactcgtata accgctgcat ggcaggatca
     6361 tcggcaagca tccgcaagtg attgccgatc acattctcgt cataacggat ggccggcccg
     6421 gtctgggccg tcttaggttc cagttcgtgc accttacggg cggtttcatc aatcaacggc
     6481 aacatcacgt caaacggcag attgtatttc ttaagcaact cggcagcaag ggcatacatg
     6541 tgattggtga agttacatgt aaacacggca gccagatgga gacttttacg ctgctccgag
     6601 tcggcatcgt acacacggtt ggacagtgta gaggcaatgg ctttcagaaa cgcggcatct
     6661 tctaccgaag aagcctctat gaagaaagga atctccttaa aatctacctc tcgctgcttg
     6721 ctgaaagtct gcatgggata gaacacaccg taatgcgaga catgtccttc ccagacattc
     6781 atcgggatgc tacctgccgt atgcaccatc aatgcctctt cccgcttacc ttcgacaatg
     6841 ccctgaagaa gttcggcaaa ggcggaatct ttcagtgaaa caatatacag cttcgcatac
     6901 gggttcacct ctgcgaggtc tgtcgtatat tcggcttcca ctttctgtgc cagctcgcgg
     6961 gccgactctt ccgtacggct atacacctgt acgatacgaa aacctttccg atataaggct
     7021 tttgccagat tagtggcaag atttccggca ccgataaata cgatcggcgt atcttctata
     7081 cttcttttca tcgtgttgaa atcaaataca atatacctcc gattatcaat aaagccaaag
     7141 gcagcagata accggacatc gaaccaagca acgaaacaat caggccgatg ttcagcacca
     7201 accacaatcc gagcaatacc aagccgacgg atttatcccg cttaataaac aggaaaatca
     7261 ccgcagtgta aagcaaaaga ttatccttat tcatcaccca gggtatcccc aaagtggaaa
     7321 agtgtatcag tttgtcgatc agatagagca cccccatcac aataagggtg actgctgtgg
     7381 ctttgtaggt atctttattg tttgctttta ccgcactcac cgttacttac ctccgaactt
     7441 attaatatgg attttttccc attgcaaatg gtcttcatta aagggtttac gttccatccc
     7501 tttatgcccg atcgctatga cggacaacac ctgcaactgt aaaggaatgt cgagcacacc
     7561 gcgcacaaat tcatcggaag gcatcccggt ggcagtatac cgctcacgca cctgcaccca
     7621 gcaacttccc aatcccaagt cttcggcctg aagctgaatc ataatagagg caatagaagc
     7681 gtcctcaatc catacatcgc tcgccaaggg atcggcagta acgacaatgg ccaatgccgc
     7741 gtcggcaata aaggccgaag cctgctcttt gcaatgtgaa agttcactga gcaacttttt
     7801 atcatcgact gcaataaact gccagctgtt actgcgcttt gaagtaggag ccatcagggc
     7861 cgctttcagc aaagcgacta catcttcctg agaaagttct tctccggtaa atttccgcat
     7921 gctgcggcga ttttttatta gttcactgaa attttccatg tatctatact ttgcattatt
     7981 tgaatatacc gccagtcacc atagaatgca caaacacacg cgaaccgagg taccgcccgg
     8041 catgcccgtc tatataaggt atgccctgca ggactttgca tgaatcggcg cgctccgtgg
     8101 cgattcgagc gcaaagatag gcaatttatt ccactctcgt caactcgccg gtcagtgaat
     8161 cgatgataaa accatgcacc cggacatctt tcggaataag cggatggttc tctatggaac
     8221 gaaccgtgcc cctgacggac ttcaccggat cgtcgaatcc gcccagccac gaattaaaat
     8281 cgaccccgca gtagcgtatc atgtcgattg tttcggactt gattccccgc tttttcatgt
     8341 gagctatcat ttcgtcgctg ttcatgtggc aagcaccgca atcagaatgg gcaatgacca
     8401 tcacttcttc tactcccaac tcgatgatgg ccaccagcag actacggatg acactgccga
     8461 aaggatggga aatgacggca ccggcattct ttataatctt tacgtctcca ttgtgaattc
     8521 ccaaagcggc gggcaacagt tctgtcaggc gggtatccat acaggaaagg atggcgattt
     8581 tcttatcagg atacttgtta gtgatatact tttcgtatcc cctgttctca acgaactttt
     8641 tgttgaattc aagaatttct tctaacataa tcaaaaacgg attttattgt agtatctcca
     8701 caaagatagt cacaaaacga cagctcaaca aaataagccc tgcaaatgtt gtaaagagaa
     8761 ataaaaaatg taaatttgtc ccgatatgcc attaaaactg actacatatt accaaggaag
     8821 tgagattccg gattttcccg gaaccaatac gtttcattcg aaagagctat ttcagatcta
     8881 cgaagaaact ccgggctaca ccccgcttct gattatggct tcggaagacg gaaaacctgt
     8941 tgcgcgactg cttgctgcca tccgcaaaag catccgcatg tttcctcccg ctttcatcaa
     9001 acgctgcgaa atctatggca cgggcgaata tctgacagcg gaaaccgaca aggaaaggat
     9061 attcggcgaa atgctggagc acctcaccac ggaggctttg cggaactcgt ttctgataga
     9121 attccgcaat ctggagaacg ccatgttcgg ctacaaatat ttccggtcca acagatactt
     9181 ccctgtcaac tggctgcggg tacgaaactc gcttcacggc atcgaaaacg ccgaacagcg
     9241 tttcagcccc tcccgtatcc gccagatcaa aaaaggcctg aaaaacggag caaaagtaga
     9301 cgaggcacgt acggtagaag agatacgcga attttcgaat atgctgaggc atctctattc
     9361 gtcccgcatc cgtaaacatt ttcccaacat catctttttc caacacatgg acacccggct
     9421 gattcacagc cggcaggcaa agattttcat cgtccgctac aaagacaaaa ttatcggagg
     9481 ctctgcctgt atctattcgg gaaacgatgc ctatctctgg ttttcgggag gtatgcgaaa
     9541 gacctatgcc ttgcaatacc cgggtatact ggctgtatgg aaagccctcc aggatgccca
     9601 tcaaaacgga ttccgccaca tggagttcat ggacgccgga ctcccattta agaagcacgg
     9661 ctatcgtgac ttcgtgctcc gcttcggtgg caagcaaagc agcacccggc gatggttccg
     9721 tttccgctgg caatggctga acgacctgct gatcaaaata tacgtctgaa catccgcctg
     9781 tctcagggat cagcgccaac cctctccgcc ttttaaacca cccccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccaggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatc gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagcggtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct tggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgct gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaacc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac agccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat tggtaatgca ggtgtatccg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt tcattagtaa ggtagacgtc cttcttttcg caaagaaggg cgtctttttt
    14701 ttgcgttaat ctatctaaaa gatattacga acctttcgta gaatggatat ttttactaac
    14761 ttgcggacaa taaaacaata cgtcctatga gaacaagaac aatgaaacca ctcttcctta
    14821 ttttctgtct ttgcctcagt cccctactga tgggccagaa tcaaaacaaa attcaggaag
    14881 caatggcaaa ctatgactac gagactgccg ttgaactgat aaacaaggaa cctcccacca
    14941 tcccactgtt aatgcagaaa gcaaaagccc tgaaaggaat cggcagcaat gcggaagctc
    15001 tacgctccat ccgccaagtg atagcggaag actccaccaa ccaacaggca cacatcgaag
    15061 cagcggaatg ctgtaaagca atggccaagt acaacgatgc gctggactac taccggaaag
    15121 ccatcagcct gaatcccaaa aacaagtatg cccgtttgca attcatcaac ctgctttgca
    15181 acaccaaaaa ctatgctgag gcttttggag aaagttcaat gatgtccgaa acggacagtt
    15241 cggccgtagt gctccaccta caggctcaaa gccttgaagg gatgcaacag atactaccgg
    15301 ctatcggttg ctatgaagtc attcaggata aatatccgga cgattatctg gctgcggcca
    15361 aactcggaaa cctgaacatt gtggctggat atcccgaata tgccatccaa gctaccgaac
    15421 gctataggga acgggactcc accaacctga ttgtcaacca gcaaaacgct ctcgcctact
    15481 gccacgccga acaatatccg acagccatca agcgctatga aaagctgtgc caacaggggg
    15541 acagcagtac acagacctta tactatctgg gagtcagcta ttacgcggat gaatattatt
    15601 acgaagcgca cgcgtgtttc agcaaactgc aaaaagagat ggaagaaaat cccaatctgc
    15661 tctattatct gggacgttgc tgcgccaaga cttcctggaa aaaagaaggc atcgaacacc
    15721 tggagaaagc tatcgaacta accattccca aagacagcac catgatccga ctttacaaag
    15781 gcttggtgga ttgttgtaaa ctggctcagg atactccaaa gcaaatccag gctctcagag
    15841 aactgtacaa atatgacaag acgaaccata aacttcttta tgacatcgcc tggaactatt
    15901 catatcaact caaagacaac aaatcggccg aacgttatct gcaggctttc ttaaaaaccc
    15961 gaaaggcgaa tgccaggaaa gaagaaccgg tgagtgagaa aggggaactt gtactcggac
    16021 ttgaaaatta ttacaacgct gccgaaaatt ggctgaaaga cttacagaaa gaaaagttct
    16081 tcaaagaagg aataccgtta gaaagtcaga aacaatagaa tctgtccccc catgaaacat
    16141 tggatactcc tcctctatct ggggttcagc gtagtgctgc aagcccagaa caccgcctcc
    16201 gttcaagaag caatggcaaa ctatgactat aaaacggtga tcagactgat tgatgaagaa
    16261 agtgcatcac cacagttact catacagaaa gccaaagctt taaaaggttt agggcgtacc
    16321 gccgaagccc tgtccacttt gcaacatatc attatcgagc tgcccgaaaa tcagcaggca
    16381 ttggtagagg cagcagaatg ttgcaggcaa ttgagcaaat ttaacgaggc cttggggtat
    16441 tatcggaagg tgatggaact caatcccgaa catatttacg cacacttgca atacacccgc
    16501 ttgttataca actatcagcg atacggcgat gcattgcgtg agagtatcgc attggccagg
    16561 aaagacagtt ccgccaccgt attgcgactg atggcggaaa gcatggaagg agccggcatg
    16621 ccggtagaaa gtatgttttg ctatctttcc atcatcagga aatatccctc cgactatctc
    16681 tcggtagcta aactgggcag tatcttcaat acaatgaaag attacgaagg ggcaattgcc
    16741 ctgacagagg cataccgccg gacggacagc accaatgtag aagtgaaccg tcaaaacgca
    16801 ctggcgtatt gtctgcgcaa agaatatccc accgccatca aacgttatca ggatctgacc
    16861 gcccggggag acagcacact gctgacatgt tattacctgg gagtcagcta ctacgctacg
    16921 aaaaaatact ataaagcgcg cgattggcta ctcaaagcaa aatcatgcca gtcacccggc
    16981 gctaacctac tctactattt gggacgttcg tgctccaaga cattatggaa acaagaggaa
    17041 ataggatatc tgaaccaggc tatcgccctg actatccccg ccgacagtat catggagcgc
    17101 ttatactcag gcttggcaga ctgctacagg caaaccaagc aaacccggga ccaaatcaag
    17161 gctaccaaag aacaatacaa atatgcccct gacaagcata ttttacttta taacttggcg
    17221 ttcttatcgg acaaaattga agatactaaa gccacagagc attacttgca ggcttttctg
    17281 cgaacaaaat ccaaacaaaa tgcagtacta cagcagccgg atgatgacga agaagaaccc
    17341 gcaccctaca tagattacta caaaagtgcc accaataaat tggaaagcat ccgaaaagag
    17401 aaattcttaa agggagaaaa gtgaattgat cggatagatg catcgtttcg gacaattcac
    17461 cactgagtgc agacagagtt tcacagaggg agaataatgg aaaataaatt tgaagatgtg
    17521 cggtagaagg cacagtggca cgtaaccgaa gtcacatcgg cacgcagccg aaattactgt
    17581 gctgtgtagc taaagttacg gtgctgtgta gccgaagtta cggtgctgcg tagataaagt
    17641 tacggtgctg cgtagccaaa gttacggtgc tgcgtagata aagttacggt gctgcgtagc
    17701 cgaagctatg acggcatctc cttttccgga cgtcacgttc acctgattgc atcgaaaagt
    17761 gctccttatc ggttgagctc catcccggag aattctccaa tgaaaacgtt tgcataaata
    17821 gatggcacac agtaagaaag aaaacggaaa acaatccgat gatttaccct atattagcaa
    17881 cattaaataa taacgagcta atatcatgaa aaaattattg ttactcttag gttcattcct
    17941 actgtcatta accacttatg cagccatgaa catatccaaa atcgatccgc ccttctggtt
    18001 caccggtatg aacaatccgg aactccagtt aatggtatac ggtgaaggca tcggccaggc
    18061 atccatatca gtaaattatc ccggtgtatc gctcagcagc gtcgtgaaac tggaaagcaa
    18121 caattacctg cttgtctacc tgcatctcga taaagaagta aagccgggca agatgcccat
    18181 cacatttacg gtcggaaaga agaaattggt gaaagagtac gaattgaaag cacgcagcaa
    18241 agccggagtc gatcacaaag gttttgacgc atcggatgca ttatacctgc tgataccgga
    18301 ccgttttgcc aatggcaatc cggataacga ccggatagaa ggcatggccg aatataaagt
    18361 ggaccgcaac gacccgaacg cacgtcacgg aggcgacctg gccggtatcg aacaaaatct
    18421 ggactatttt accgacttgg gagtaaccgc actctggttc accccggtac tcgaaaataa
    18481 tatgaaaggc ggctcatatc acggatatgc aacaaccgat tattacaagg tagacccacg
    18541 tttcggcact aacgaggaat atcgctcact gatagcgaaa gcccacaacc gggacattaa
    18601 ggtcgtgatg gacatgatct tcaatcattg cggagtagaa catccctgga tcaaggacat
    18661 gccttcaaag gactggttca accatgcgga cttcaagaac aactttgtac aaacttccta
    18721 caagctgact ccacatgtag atccgtatgc ctcggagtac gatttcgacc agatgaacaa
    18781 cggctggttc gtggaagcca tgcctgacct caaccaaaag aaccctcacg tatacaaata
    18841 cctcttgcag aacagcctgt ggtggattga gtacgccgat atcgacggca tccggatgga
    18901 cacctacccg tatgccgatt acgatgccat gagcaactgg atgaaagaac tgaacgaaga
    18961 ataccccaac tacaacacgg tgggcgaaac ctgggttacc gaaccggcct atacagcctg
    19021 gtggcagaaa gactccaaac tctccgcccc gcgcaacagt cacttgaaaa cagtcatgga
    19081 tttcagcttc ttcgacaaag tcaacacggc caagaatgaa caaacggaca cttggttcaa
    19141 aggattggac cgtgtctaca acaattttgt atacgattat ctgtatccca atccggcttc
    19201 cgtactggct ttcatcgaga atcatgacac cgaccgtttc ctgggtgaag gcgaaaacct
    19261 cgatatgctg aaacaggcct ccaccctttt attgaccacc cgacgcatcc cgcaactcta
    19321 ttatggaacg gaggtgatga tgaacggagt aaagagtaaa agcgacggct atgtacgaaa
    19381 ggacttcccg ggcggatgga cggacgataa agagaatgcc ctgactcccg agggacgtac
    19441 ccgattgcag aatgaaagct ataacttcta ccgcaacctg ctgaactggc gtaagggcaa
    19501 cgatgtgatc gccaaaggca gcatgaaaca gttcatggtg cagcacggcg tatatgctta
    19561 tgcacgccaa tataaaggga aaacggtatt cgtcctgttg aacggtacgg ataaagaggt
    19621 gaaacttccc ctgaaatact atgccgaagt gctgaaagac aagactcaag gaaaagacgt
    19681 cattagcgga aaagtaacgg cactcaatga agaactgaca atggcacccc gccaatcgat
    19741 ggttatagag ctttaatctc acaccggtta taaccgcata agcaaagggc acaaaggatt
    19801 tcacccgaca tcctctgtgc cctttgtgta gcctaatgcg aataataata gtcaaacatt
    19861 tgactattat cgaagaatat tcctaccttt gcagcgacta aaagaatacg acgatgacaa
    19921 acaacgaatc ggagcgcgag ctcgtcctac aaaccttacg aacctggatg gcattccgcc
    19981 aggccgttca gcgggtactc aaacgtcaca acgtggatat gaccttcgag atgctgcaag
    20041 taatgaactg cctgtggaac aaacaaggca tcagccagca atccctggct gagaaaacag
    20101 caaaggacaa ggcttgcctg accaatctga ttaataatct ggaaaagaaa aactgggtga
    20161 tacggaaaga aggcccctcc gaccgccgaa accgcctgat tttcctgacg ccccaaggcg
    20221 aagaacttgc cctcaccgtg aaacccctga tcaacgatat ctatgcccaa accggaacag
    20281 agatggaggc aagccggata acggaatgca tcgaagatct gaagagactg catgaagtgc
    20341 tcaatgagat ctaaaagaaa tccgccatgt ccacccatca gataaagcta aaacaattga
    20401 gaagactgaa gttcaggaac atctttctca acacagtatg catcctactg gcattggcag
    20461 gtatttcatg gacagtaaac tacttctgga aatacgcccg ctacgagata accaatgatg
    20521 ccgtagtgga tcaatacatc gctccgctaa acatccggat accgggctat atcaaagaag
    20581 tacgttttac cgaacaccag tatgttcatg ccggcgacac gttactgata ctggacgacc
    20641 gggaataccg gatccggctg aaagacgcgg aagcggcctt gatggatgcc ttgggatcaa
    20701 aggaagtgtt aaactccggc atccggactt caggagtaaa tgtagccgta caagaagcca
    20761 acatagccga aacactggca cgcctttcac aacaagaagc ggaactgaac cgatataccc
    20821 ggctcctgaa aaagcaggcc gtcagccaac aggattatga actggccaaa gcgaacttcg
    20881 aagcgacccg ggcaagatac aacgccctgt tgcgacaaaa agaagcggcc caatcgcagt
    20941 attccgaaac cagcaaacgc agtacaggcg ccgaagccaa tatcctccgg aaggaggccg
    21001 acctggagat ggcccgacta aacctgtcgt ataccgttgt caccgcaccc tatgacggat
    21061 acacgggacg acgtacactt gaaccgggac agttcgtaca aggcggacaa actctttcct
    21121 acctggtacg gggcaatgac aagtgggtga cagccaatta taaagagact caaatagccc
    21181 atatctatat cgggcaaaaa gtccgcatca aagtagatgc tttcagcgga cgcacttttc
    21241 acgggaccgt aaccgccatt tccgaagcca ccggatcgaa atactccctg gtaccgaccg
    21301 acaattcggc agggaacttc gtcaaagtgc agcaacgcat tccggtccgc atcgatctca
    21361 atgacgcctc acccgaagag atggaatgcc tccgtgcagg gatgatggta gaaacggaag
    21421 cggtccgccc ttagacttat ggtgaagctc aatctgccta cccgtccctg ggtgcctcaa
    21481 tggttgggca tcgtgaccat gtttattgtc atctttccca tcaccctgct caacggtgcc
    21541 tacacaggga gtatggtcga agtatcgaac acgctgggag tattgagcga agatattacc
    21601 atggcttact attcagcttc ggtagggatg gctgttgcct atcccatcgt accgaaaata
    21661 cgcaccatag ccactccgaa aaccttactg cttaccgacc tgctgctaca gatattcttc
    21721 agcctggtat gcgcccaaac cggtagtatg gacgtcatca tggtatgcag tttctgtatg
    21781 ggatttctca aagccttcgt catgttggag ttcatcatcc tgatccgccc gctcttcagt
    21841 ccgaaaaacg tacgaagtga attctatgcc tacttctacc ccatcgtttt ctccggaggt
    21901 cagctatcga tggctatcac cgctcaactg gcctatcact accaatggca gcacatgtac
    21961 tattttgtca ccatcctctt gctgatcgcc attctgttcg tcatctgttt cttccgctat
    22021 gcaaggcgtc ccatgcacat tccgttcaaa gagatggacg gaagaagcat gttcatcatc
    22081 gccaccgctt tcctgctaac gctctataca tttacctacg ggaaaacact cgattggttc
    22141 gcatccccga agatcagagt atatgtattc gtcatcccgc tcctgatagc tctcttcatc
    22201 catcggcagc gtacacaagg caaacccttt gtcagcctga aaccactctt tctgcataaa
    22261 tccatcatcg gatatggctt catggtactc gccatgttcc tgacagccac cagttcactg
    22321 gtaaccaact atatgaacag catcatccgg gtagacagca tacacgccaa ttcgctgagc
    22381 ctgtggctat tgcccggata tgtggtaggg gccgtcattt gcttctggtg gttccgatgg
    22441 caacgatgga ggtttcgctt cctcatttca ggaggtatgt tctgctacgt catctatctg
    22501 gctatcctct actttggtat caccccttat ggaacttatg aaatgctcta cctccccatc
    22561 ctgttccggg gagtggggat gatggtcata ttcattgcgt tcggtgtgtt tgttgtcgaa
    22621 gatttagacc cgcgcctgac gttgtccaat gccttcttcc tgatttcatt ccgctcagta
    22681 ttagctccgg tcctgtccgc ttcgttcttt aacaacatgc tttactatct gcaggcaaag
    22741 gggatgaaca ttctttcgga aaacatgacg ctgaccaatc cgctggccga acaaaaatac
    22801 aatcaggcat taagcaatgc cctggcgcaa gggcacgaat tcggcgaggc cggacaattg
    22861 gcagccaaca gcctgtactc cactttgcag cagcaatccc tgctgcttgc cctgaaaacc
    22921 ctaatcggct atgtactgat actggcactg gtgattgctg tcatcgcagc gttcattcct
    22981 ttccataaaa cgctgaaggt ggctgtagtg aagacgggtg acgatatggt ataatgagaa
    23041 gggatacaaa aaagccaccc aattgcttga gtggcttctt aaaatataaa ttaaatcaag
    23101 taaaactttt aaatactaga tttggaattt attcagctaa cttgttgtca gaacccagca
    23161 cgttgataat tttgtgcttg tagagttttt ccatattgtc gcgagccggt cccagatatt
    23221 tacgcgggtc gaactcagcc ggtttttctg cgaatacctt acggatagca gcagtcatag
    23281 ccaggcgaga gtctgagtcg atgttgattt tgcaaacagc agacttagcg gctttacgca
    23341 gttcctcttc aggaataccg atagcagctt tcagtgcacc accaaactgg ttgatagttg
    23401 caacctcttc ttcaggaact gaagatgatc cgtgaagaac gatagggaat cccggaagtt
    23461 ctttcattac accgtccaat acgtcgaatg ccaacggagg aggaaccata cggcctgtct
    23521 tcggatcgat gtggcactgt tccggagtaa atttgtaagc accgtgagaa gtaccgatag
    23581 agatagccaa tgaatcgcaa cctgtcttgg taacgaaatc aactacttcg tccggttcag
    23641 tatatgtgtg gtggtcagaa gaaacttcgt cttctacacc tgccaatacg ccaagttcac
    23701 cttctacagt tacatcgaac tggtgagcgt attcaacaac tttcttagtc agagcaacgt
    23761 tttcgtcgta aggaaggtga gaaccgtcga tcattacaga agagaagcct gagtcgatac
    23821 agcttttgca agtttcgaaa gtatctccgt ggtcgaggtg caaaacgatt tcaggatttt
    23881 tgcagccgag ttcttttgca tattctacag caccctgagc catgtaacgc aacaatgtag
    23941 cgttagcata ctgacgagca ccttttgata cctgcaaaat aaccggagac ttagtttcta
    24001 cagcagcctt gatgatagcc tgcatctgtt ccatattgtt gaagttgaat gcagggattg
    24061 catatccacc cttgatagcc ttagcaaaca tatctctagt gtttaccaga cctaaatctt
    24121 tgtaa
//
