LOCUS       gnlProkkaDKJOAIGO_16   14042 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKJOAIGO_16.
ACCESSION   gnlProkkaDKJOAIGO_16
VERSION     gnlProkkaDKJOAIGO_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:10:17
            Original ID  :: gnl|Prokka|DKJOAIGO_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14042
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14042
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3697:4042]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3698..4042
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14042
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14042
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..256
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MTHQPSVPAIIHAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVE
                     KEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEYELD"
     CDS             243..770
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MNWIKKIARPLILIVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             775..1569
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTVEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             1576..1971
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             2262..3650
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.6; E-value: 6.7e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENRKKGYGLEEA
                     NIQK"
     CDS             3698..4042
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="PF05402 (E-value: 7.8e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 3.3e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEREGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             4063..4155
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKDCP"
     CDS             complement(4129..4416)
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(4438..5502)
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNTIAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRDK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMDGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(5576..7087)
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     KTPVTIFAGPGNNGGDALAVARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDASETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVVDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             7748..7972
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVALAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             complement(8159..9817)
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="MKHYFYLILLFIFCSCSNDKDTDSLLLSKDKLTFTWLGGMEDISV
                     EANDSWFVPSTMPSWITISESQGKSGNYSISISVSENNTGEIRAYQVSFTVAGTDIRKI
                     LQITQTAKENLAFIGEKEYVISPDATKLSLEITQNVNYQLRISEEAKEWITQSNSWEDS
                     GKDISNRITTNSIKIDNNTNITGINKIQFSITANKTKEERHAKVAIYNYAYNLSDSVYI
                     VQKAGDGINNYQDGEYIRLQQATIPNGVNLIFIGDGYTQQDMTLNGRYEKIMRQAADYF
                     FSIEPYKSYRNYFNTYMVIAESKEAGVGVTNTFNGAVNNKFKTTFGNGTEITCNADLCF
                     EYARKIKELPSNKPLTIIMPLNSTKYAGTTYLYANGNSIALCPMSEEASPNDFEGLIHH
                     EAGGHGFGFLCDEYIYYKQKMPESRKKDLKEWQKLGFQMNLDFTNDLSTILWKDFIGIE
                     KYSQAGAYEGGYEYQYGVWRSEANSCMNNNIPYFNVQSRWSIVSRIMKLAEINNFTIQD
                     FISSDHTTSLNRTTIYSNTSGITILPPLGCPKWIK"
     CDS             complement(9848..10234)
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MKYLSMMLVILAMSVCMASCGDDDDESGNILAGTRWAYSDVYEDG
                     TSEVSLTFNADNTAVWNYVIRNAGGTIVTNETAGYNYQISEDLVVMTAQQAGKANLEGT
                     ISSGVKMEVKNMSTQKSVGTFYKK"
     CDS             complement(10350..10562)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKPIGHLIKEELEKQERSISWFARKLSCDRSNVYRLFQKENIDTG
                     LLTRISLLLNHDFFADLSENIKEKY"
     CDS             10943..11041
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MGVHKGKGNLLKKTNVKTELNTILVPLHPINY"
     CDS             11054..12598
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFLILGNGCFKPTVTSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVILFETQKNKYLFSPSGEPIGIVPDAKRERK
                     EDKAEHISHPKMDKRTKIRNIIIITALTAALIAFFSYAFSGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDILGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVSKLSPLRFASLMMGIWYLSMATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFLLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             12640..13176
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             13210..13779
                     /locus_tag="ctg16_18"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLEER
                     GQDISVMLDLEVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
ORIGIN
        1 gacgacgcac caaccatccg tgccggccat tatccatgct gtgcagcaac cgtctgtttg
       61 tcccaaagaa gacgatgacg atattcagga cacggaagaa tatgtggaag aaaccctttc
      121 gctcgatgaa gtggaaaaag aaatgatacg taaagcgctt gagaggcatc atggtaagcg
      181 gaaaagtgcg gcgaaggatc tgaatatctc cgagcgtacc ctttacagaa aaataaaaga
      241 atatgaattg gattaagaaa atagcacgac cgctgatact gattgtttta ccggcagtca
      301 tcatcgcctg tagtgtgtcc tataagttta atggctcctc tatcaattac gataaggtga
      361 agaccatttc gattgctgat ttcccgatta agtcggagta tgtgtatgct ccgctggcta
      421 ccaagttcaa tgaagacctg aaagatatct tcatcagaca gacccgtctg caactgctga
      481 aaccgaacca gaatgcggat ctgcagattg acggtgaaat tacgggctac aaccagtata
      541 accaggcagt gtctgccgat ggttactctt cggaaacgaa gctgaccatc acggtcaatg
      601 tacgctttgt caacaacaca aatcacgccg aagacttcga acaacaattc tcagctttcc
      661 gtacctatga ttccagccag ctgctgacag ccgtacagga tggattaata gcggaaatga
      721 gtaaagagat aactgaccaa atatttaatg caactgtagc aaactggtaa tttaatgact
      781 tctgttaact tgcaacaatg gattcagcat cccgagacgc tgaataggga tactttgtac
      841 gaactgcgca accagctcgc gaggtatccg tattttcagt cgctccggtt gttgtatctc
      901 aagaacctgt atattctcca cgacattaat ttcggtgcgg aactgcggaa agccgttctg
      961 tatattgccg accgacggaa actgtttcat ctgatcgaag gcgaacgctt cgctgtcgaa
     1021 tcccagaaga aagggctgcc tctctctgaa gtattgaaag atgagcctac cgtcgaccgg
     1081 acactggctc tgatcgatgc tttcctttcg acggctcccg aagaagtaac cagtcagaca
     1141 agctttgatt actccatgga ctatacggca taccttctcg aagagacacc tgtcgccgac
     1201 gagccggcag aggcaatgcc caagctgaaa ggacacgagc tgattgacaa ctttatcgaa
     1261 aaaagcgaga ctgatccagt cgtatacctg aaacctttga gggaagaaga gaaagcaaag
     1321 gctgcttctt ccgctgaaac aaacgaaacg ggcagaacag acgaaacaac tgaaaccaac
     1381 accgtagaag aggaagatga cagctgtttc acagaaactt tggccaaaat ctacgtaaaa
     1441 cagcaacgat attcgaaagc tcttgaaata attaaaaaat taagcttgaa atatccaaaa
     1501 aaaaatgctt actttgcaga ccaaatcaga tttttggaga aattgattat taacgctaat
     1561 tcaaaataac taaaaatgta cttattattc attatcttaa tggtgattgc agccttgctg
     1621 atgtgcttca tcgtgctgat tcagaattca aaaggaggcg gacttgcttc tggtttttct
     1681 tcatcaaacg ctatcatggg cgtgcgcaag actacagatt ttctggaaaa agcaacttgg
     1741 ggtctggcta tcttcatggt tgtgatgagc gttgctactg cttacgttgt tccttcttct
     1801 tctgcagcta aagatgtatt gttggaacaa gcacagaaag aacaacaaac caacccgtat
     1861 aatatgccta ccggtactgc tgctcctcag acagacgcta ctgctcctgc agagtctgca
     1921 cctgcaacag aagctccggc tactgaaact cctgctcctg cagcagaata attcagtgac
     1981 aggatattcg gtttaaactt attgagtgaa cgggcttttt gacccgtttt cttcattata
     2041 ggcgcgaatt acgcgaatta caagagattc taatagaatc gtgtaatacg tgtggttcgc
     2101 gcctatcttt attattgggt ccggtctgct cttcttcata caggaatatc cggtcagatg
     2161 tcctttttct tataaaatgt tctccttttt tagtaaaaca aatgataatt agttaacttt
     2221 gttgcccgtt acgagattat taactccttt taaatattac aatgacagaa caattgaaac
     2281 aaaagctgaa tgactccgca gtgctgcgtt ggagtgttct agcattagtc gcttttacca
     2341 tgttgtgcgg ctacttcctc acagacgtta tgtctcctct gaaacccatg cttgaaaaag
     2401 aacttctctg ggacagttta gattacggtt tctttaccag tgcttatggc tggtttaatg
     2461 tattcctgct gatgctcatt tttggtggta tcattctgga taagatggga gtacgcttca
     2521 ccggaatggg tgcctgttta ttgatggtgt tcggttgtgg attgaaatat tatgctattt
     2581 ctactacttt cccagagggt gcgatgcttt tcggattcaa gatgcaagtc acattggctg
     2641 cattgggcta tgccatcttc ggtgtaggag tcgaaattgc gggtatcacc gtttcgaaga
     2701 ttattgtgaa gtggtttaaa ggcaaggaga tggctctcgc tatgggactg gaaatggcta
     2761 ccgcgcgcat tggaacgact ttggccatgg tgcttaccgt tcctttggca gacttcttcg
     2821 ggtctacgga tgagagcggc gtattccata ccaatattcc cgctccgatt ctgttctgtc
     2881 tcgtcatgtt gtgcgtaggt accatcgcat tcttcatcta tactttctac gataagaaat
     2941 tggatgcttc actggatgcg gaaggactgg aaccggaaga acctttccgc atgaaagaca
     3001 tcgtctatat cattactaac aaaggattct ggctgatcgc attactgtgc gtattgttct
     3061 attcggctgt attccccttc atcaagtatg cggccgattt gatggtacag aagtacaatg
     3121 ttgatccgaa acttgcggga acgattcccg gattgctgcc gattggcgcg atcatcctga
     3181 caccgttgtt cggttcattg tatgaccgta tcggtaaggg agccacgctg atggtgatcg
     3241 ggtcggtgat gctgattttc gtacacacga tgttcgctct tcctattctg aatatctggt
     3301 ggtttgcaac ggtgatcatg attattctgg gatttgcttt ctcattggtt ccttcggcga
     3361 tgtggccttc ggttccgaag attattccgg agaaacagtt gggaacggct tatgcgctga
     3421 tcttctgggt acaaaactgg ggattgatgg gcgtgccttt gctcattgga tgggtgttga
     3481 actcttattg caaaggtccg gttgtagatg gtgcacagac ttatgattat actttgccga
     3541 tggctatttt tgctatgttc ggtgtacttg ccctgattgt tgccttgatg ctgaaagccg
     3601 aaaacaggaa gaaaggctac ggactggaag aagcaaatat tcagaaataa tcacagtata
     3661 tattctatct gaaacaaaga tataaaagag aaaagatatg gctacgaaag agaaaataaa
     3721 cctcctggag gtgatccctt gtcgtaacga acatattaaa gctgaacggg aaggggagac
     3781 tattgtgctc tccttccctc gttttaaacg ttcgtggatg agtcgttatt tattgccgaa
     3841 aggaatgtcc aaagatattc atgtgcgtct ggaagaacat ggtacggccg tatggaacct
     3901 gatagacggt cagcggacgg ttcgtgagat tatagaaaaa ctcgcagacc actttcagca
     3961 tgaagcaggc tacgagtctc gtgtatctac ctatctttcc caattacaga aagacggatt
     4021 tattaaatgg ataattgatt aatggataat tgataatgga aaatggataa tgaggttgag
     4081 cagctggaat attatcccat acgttcatta tccattatca attttccatt atccattaaa
     4141 aaagattgcc cataggagga cagcacatcc tatcagtacg cccataatga tgagcgttcc
     4201 ccatacgaaa tagctgttat ctttttcttt tttcttttcc gaatccttga tgatgcgttc
     4261 catctcttcc ggagtcgtat ccggcagaag ataagggtcg ttgtttctcc tgagtcgccc
     4321 taacttgtca tttctccgtt cacggcgtaa gcgggaggct tctttgccgt ctttcagccg
     4381 acgtatcatg tcgagcatat gtccttcgcc acccatcgtt ttgttttttt agaggtttta
     4441 tttgctttct tctctatcta ctttcagtag tccaccggtc accggatcaa agtaaacttt
     4501 gatggtcgag ttcttgttga ataataccgg agcaaggtat tctatgatac cgaattgggt
     4561 aacaggtatt tctccttcat acaatttctt tttgccgtcc gtcagcgtca ccattgcctg
     4621 tcccggtaca ttataagcaa ttccatccat ctctttcttc tttttcccgt cctcttgcgg
     4681 aatcttcacc gttttcaggt ctttcagact gatgtagaat ggagtgcctg ccaaatcgtt
     4741 gttggcaact atacccagct tctttgaaaa gcggaaagct acctcattgt cgaactcttt
     4801 atccggagtg aggcggacag taaatgtctt ttcttcttta tcgcggactc ccgagaacat
     4861 ttcagtcata gcctcttcct gaagattcag gttgtcgagc atgattttga gctgtgcgcc
     4921 gtccgacggc atattatctg cttgtccgcg caataatgcg tttttacttt cgcggatatt
     4981 atagatttcc tttgctacca gttcggccat cttggcggtt gaacttgcca tcagaatttc
     5041 ttctgtgagg aagtcgcggg gattggcttt tcgttggggg gcaatggtat tgtttgctgc
     5101 attctttgca ttgttgctac tgtaggggac gttgatcgat ttgataagac cctcttcagt
     5161 cagttccata agaggagcta cggttttgtc tttcagtttg acgaaataag tggcttcgct
     5221 gtttggtaca cctacaggct tcaccttgac gctgttcaat tcccagtatt cttcgggttc
     5281 ggcagagacg ttggtcagtc tcaggtagcg gtcggcatat ttgctgaatt cacccggctt
     5341 atagttgact ttgtttgctt ttatttctat ttctatctgg gttttgggga gggcgtacac
     5401 tactccgtag tcttttcctc gcgtcactcc tgtcagcact tcggtctgcg cataggcgga
     5461 agttgccatt agtagtcctg ttgctatgat taactttttc atattcggtt ctttttagct
     5521 gattttgaaa aacaaagtta atgaagttat tgaataaacc gtaagttctt aacttttatt
     5581 cgcttacaag tcgccatgcc gtcggcagac aggtcacgat atcacttgcg attaatccga
     5641 tcatgccctg ctttttctgg gcgatgtctc cggccaatcc gtgaatgtaa gtaccgatct
     5701 ttgcggcatc ttcggcagga tagccttgcg caaggagtgc aaggattact cctgtcagta
     5761 catctccgct gcctcctgtt gccataccgg gattaccggt ctggttgaag taacatttgc
     5821 cttcgggggt gataatggcg gaataagctc ccttcagaat gatatgtact ttggcagtgt
     5881 gcgccagttc gcaggctttc atcagtcgtt cgtatgagtc ttgacatttg ccgaccaggc
     5941 gttccagctc tttcgggtga ggggtgagga tggaaccttt cggcagatgg gtgagcgtat
     6001 gccggtgatt ggccagaata ttgagcgcat cggcatccac tacggtcgga gtctgacaat
     6061 gttccagttg ttctatcagg gcggcttccg tttcctcgct gcgaccgagt cccggaccga
     6121 tgccgacagc ttgataatcg tccgtatcgg taggtacggc aaagcatgtt tcgctggcat
     6181 ctgtttctac catggcttcg ggggcggacg tttgcagaat atcgttgttg cataacggcg
     6241 cgtgtacggt cagcagacct actcccgagc gcagacaggc acgggcggcc agtaccgatg
     6301 cacctgccat tcctttcgaa ccggctatca acagggcatg tccgaagttt cctttatggg
     6361 cgaattgctg gcgtggcttg atcagcgaac gaatttcttc gatttccagc atttcgtagt
     6421 ttgtttcagt ctcttcgatt ccttcttcgc tcagctggat gtccaataac tcccattcgc
     6481 caacaaattc tgtattttcg gcgaagagga aggccagttt aggaagttgc agactgaaag
     6541 tgacgtccgc acggataata ttgcttttta cattgaatgt attttcttct cccatcagcc
     6601 cggaagggat gtcgatggag actaccatgg cgggagaggc attgatatat ttcacgacgg
     6661 cagcgaatcc tccgcttaat ggcttgttga gtccggaacc gaataatccg tcgatcacga
     6721 gatgttccgg tgtcagtgtg ggaggtacga actgggtgct gatttcatgg aaagttactt
     6781 cttccatcat ctctaccagt tctttgttgg tctgacagtc gggcgaaagt tcgcctttcg
     6841 tattgaagag atatacttcg atcttgtatc ctttttccgc catcatgcgg gcgacggcga
     6901 gggcgtctcc accgttattg cccggtccgg caaagatggt gacaggtgtt ttcggattcc
     6961 atctgttggt gatggcttta gtcagcgcct gtgcggcacg ctccattaaa tctatggatg
     7021 caatcggttc atgttcaata gtataggcat ctaacttctt aatgctgctg cttggaaata
     7081 ttttcattgc gatattcttt tagttttcga cgcacaaact tacacaaaaa ctctgaatta
     7141 atcctttatt ccggttggtt ttcggcttta gataaagtgg caaattgaaa aatgcagggg
     7201 aaatcagaag ttatcttggg gtggctttgt cctgtctgtc tgtgattcct cagttggggg
     7261 cggatatttc tctgctaagg tacgggcatt cttcagataa gatgcggaga ctcttcggct
     7321 aagatgcagg cattctcctc ttaaagtgcc tttctcttta gttgctcacg gccgtgacaa
     7381 gacctcgcca cgaccgtgag caatgctaat cacggtcgtg aacaatgctt gtcacggccg
     7441 tggtcagtta atgatatcgg tgctttgatg taactattct actgctttct ccttaatctt
     7501 ccgatacttt gagagatagt tacgccttct ccggcctgct atagaactgc ttcctttatg
     7561 agtgtcttcg gcgtttggaa taaagctgtc agtagatatg gtacaatata aacagctaat
     7621 gccttgatta tttgcttttt tcgaaaaaaa tgatatcttt gtagtgcagt aatgtgcttt
     7681 acgttattct cctgtgctca caatgtttag attataaata taaattgttt aatcttctaa
     7741 agtttgcatg atggaaaaga aaagaattgg ctcaaatgcc gggaaagtat ggcgcatctt
     7801 aaatgaaaag ggcgaacagt ctatgttcac tttgtgccat gagttaggtt tgacgttcga
     7861 agatgtagct cttgctatcg gctggctggc aagggaaaac aaaatcctgc ttagaaaaaa
     7921 agaaggaatg ctctatgcca gtattgagaa tgttgaattt acttttggat aaatggcgac
     7981 tgacccacat ttaaggagaa tatccacttg attatttaca ctgttgaaaa cttaataagg
     8041 tggatagatt aagatttatt gcgtttaata ttatgtactt ttcactcatt atcttccggc
     8101 ttatttgttc catttagaat ataagttatc ttatatgcat tttcgatgct ataatagatt
     8161 attttatcca ttttggacat cctaatgggg gaagaattgt tataccggat gtattgctgt
     8221 agatagttgt tctgtttaga gaagttgtat ggtctgagga tatgaaatct tggatggtaa
     8281 aattgtttat ctcggctaat ttcatgatgc gtgacactat actccaacgg ctttgaacat
     8341 tgaaataagg tatgttgttg ttcatgcaac tgttagcttc cgaacgccat accccatatt
     8401 ggtattcgta accaccttca taagctcctg cctgactgta tttttctatg cctataaaat
     8461 ctttccataa gatagtggat aggtcgtttg tgaaatccaa attcatttgg aaacctagct
     8521 tttgccattc ttttaaatct tttttacggc tttcgggcat tttttgttta tagtagatat
     8581 attcgtcgca taagaagccg aaaccgtgtc cgcctgcttc atggtgtatt aacccctcga
     8641 agtcgttggg tgatgcttct tcgctcatcg gacataatgc gatggagttt ccattagcat
     8701 acagataggt tgttcctgca tatttggtac tattgagtgg cattatgata gtcaatggtt
     8761 tgttagatgg caattctttt attttgcgag catattcaaa gcataagtcg gcattgcaag
     8821 tgatttctgt tccatttccg aaagttgtct tgaacttatt gttaactgct ccattgaatg
     8881 tattagtgac tcctacacct gcttcttttg attctgctat taccatatat gtgttgaaat
     8941 aattccggta agatttgtaa ggctcgatag agaagaaata atcagcagct tgtcgcataa
     9001 tcttttcata gcgaccattc aacgtcatat cttgctgggt atagccatca cctatgaaaa
     9061 tgagatttac tccattgggt attgttgcct gttgaagtcg gatatattca ccgtcttgat
     9121 agttgttgat cccatcacct gctttttgga ctatatatac tgagtcagaa agattatatg
     9181 cataattata tatagcgact tttgcatgcc gttcttcttt agttttgttg gcagtaattg
     9241 aaaactgtat tttatttatt ccagtgatat ttgtattgtt gtctatctta atagaatttg
     9301 tagtaattcg attggatata tctttgccag agtcttccca agaattactt tgagtaatcc
     9361 attctttggc ttcttctgat attcttaatt gataatttac gttttgagta atttctaatg
     9421 ataactttgt tgcatcagga gatataacat attctttttc tccaataaaa gctaaattct
     9481 cttttgctgt ttgtgtgatt tgtagtattt ttcttatgtc tgtgccagca acagtaaagg
     9541 atacctgata agcgcggatt tctcctgtat tgttctcaga aacagatata gaaatggaat
     9601 agttgccact ttttccttgg gattcactaa ttgttatcca tgaaggcatg gtggaaggga
     9661 caaaccaaga gtcatttgct tccacactta tatcttccat tcctcctagc caagtaaagg
     9721 tcagtttatc ttttgacagt aataatgagt ctgtgtcttt gtcattactg caactacaaa
     9781 aaataaagag caatatcaga taaaagtagt gcttcatgga tatacaattc taaatggaat
     9841 atttaaatta tttcttgtaa aaagtaccta cactcttttg agtagacata tttttgactt
     9901 ccattttgac gccagaggat atggtccctt ctaagttagc ttttcctgct tgttgagcag
     9961 tcattacaac caagtcttct gatatttgat aattgtagcc agcggtttcg tttgtaacaa
    10021 tggttccacc agcatttctt ataacatagt tccaaacggc agtattatct gcgttaaatg
    10081 ttaaactcac ttctgatgtt ccatcttcat agacatcact gtatgcccat cgtgttcctg
    10141 ctaaaatgtt gccgctttcg tcatcgtcat ctccacagct tgccatacat acactcatag
    10201 ccagtattac tagcatcatt gataaatact tcattgtttt catcttttta tagttttaat
    10261 taatttgtgg caaaggtatg gctaaaatgt gaaatgaagt gaaaaggaat attgcggata
    10321 ctgcatcgct tttattgcgg attctgcgac taatactttt cttttatatt ttcagaaaga
    10381 tcagcaaaga aatcatgatt tagtaatagg gaaattcttg ttagtaatcc agtgtcgatg
    10441 ttctcctttt gaaacagacg atatacgtta gaacggtcac atgacagttt tcgggcgaac
    10501 caactgatac ttcgttcttg cttctcaagt tcttctttta taagatggcc gattggtttc
    10561 ataatgattt gtgtttatcg tcccaagctt cccctgataa gactgtttgt gcttttaagt
    10621 tggaaaaatg atataaaaaa gcgtggggaa tctgtacttg tcactcatcc cacacccgag
    10681 gccttcgcat tgcccagtct agttgaacga gcaacgcaga agcccacgcc gatatgtata
    10741 tagaacataa ctacatctat attgttacca aatagatcat gaaagttata taaaacacac
    10801 ccatggacat ctaccgctgc tttgttcttg actagacttt gaaagttgcg aagtttcgga
    10861 gtgtcaagac aaaacgttaa gtaaacgcct ttttatacta aatataatcc catacagcga
    10921 tttcaaagaa taaagcatta gcatgggagt gcacaaaggt aaaggaaatc ttttgaaaaa
    10981 aacaaatgtc aaaacagaat taaatactat tttagtacct ttgcacccca taaactacta
    11041 aacacataat ttcatgagtt cattgaaagg gcatccgaaa ggcctttacc taattttcgc
    11101 aacgagcacg gcagaacgtt tcagttacta cggtatgcgt gccatcttta ttcttttcct
    11161 gacgcaggca ttgctttttg ataaagaagc ggcagcctct atctacggta gctataccgg
    11221 actggtctat ctgactccgt tgatcggtgg atatattgcc gataaatatt ggggcatccg
    11281 tcgttcggtg ttttggggag cggtgatgat ggcagtcggt cagttcctga tgtttatgag
    11341 tgcctcttca ctgaacaata cagaccttgc ccactggctg atgtatggcg gactcggatt
    11401 ccttattcta ggcaacggtt gctttaagcc tactgttact tccctcgtcg gacaactata
    11461 tgaacccgga gacaaacgtc tggatgcagc atacaccata ttctatatgg gagtgaatgt
    11521 cggttctttc gctgctcctt tgatttgcgg tttcttggga gacacaggaa atccgcagga
    11581 ctttaaatgg ggattcctcg catctggaat catgacgttg tttacagtca ttctctttga
    11641 aactcagaag aataaatacc ttttctctcc ttctggcgaa ccgattggca tcgttcccga
    11701 cgctaaacgc gaaaggaagg aagataaagc cgaacacatc tcacatccga agatggataa
    11761 gcgtaccaaa atacgtaaca ttattataat cactgctctt accgctgcct taatcgcttt
    11821 cttcagctat gccttcagcg gcgactgggt gagtatcggt atttttactg cctgcattgt
    11881 cttccccgtt cttatcctgt tggacggttc gttgaccaag atagaacgca gccgtatttt
    11941 cgtcatttat attgttgcct tcttcgtgat cttcttttgg gcagcctacg aacaggcagg
    12001 agcttctctg acgctttttg catccgaaca gaccaatcgt gatattctcg gctgggagat
    12061 gccggcttcg tggttccagt cattcaatcc gcttttcgtg gtgattcttg cttatatcat
    12121 gccgggcata tggggtttcc tgaataagag aaagatggaa ccggcatccc cgaccaagca
    12181 ggcaatcggc ttgctgctcc tttcattggg ctatctcttc atctgttttg gagtgaaaga
    12241 tgcgattccc ggagtaaaag tgagcatgat ctggctgaca ggactttact ttattcatac
    12301 aatgggcgaa atcgccttgt cgcctatcgg actttcgatg gtcagcaaac tgagtccgtt
    12361 gcgttttgct tctctgatga tgggtatctg gtatctttcg atggccaccg caaataaatt
    12421 tgcaggtatg ctgagcggcc tctatcccga agacggaaaa gtgaaatcaa tccttggtta
    12481 tcagattgct accatgtacg acttcttcct gttatttgtc attatgtccg gtgttgcctc
    12541 actgattctg ttccttctct cgaagaaatt acagaagatg atgcacgggg tagaataaaa
    12601 aattgtattt ttgcgacaac ttttttaaaa tgaccggtta tggataccat acagataaaa
    12661 gacaagcaat ttactgtttc cattaaggaa caggatattc aaaaagaagt gattcgcgta
    12721 gcgaacgaaa tcaatcgtga tttggcaggt aagaatccgc tcttcctcag tgtgttgaac
    12781 ggctcgttca tgtttaccgc cgacttgctg aagcatatta cgattccgtg cgaaatttca
    12841 ttcgtgaagt tggcatctta tcagggggtg acttccaccg gagtaattaa agaagtgatc
    12901 gggctgaatg aagacattgc cggacgtacg gtagtgatcg tagaagatat tgtagatacc
    12961 ggactgacga tgcagcgtct gctggataca ctgggcacac gcaaccccga agcgattcat
    13021 atcgcctctt tgctggtgaa accggaaaag ctgaaggtca atctgaacat agaatacgta
    13081 gcgatggaaa taccgaatga ttttatcgtt ggctacggat tggattatga tggtttcgga
    13141 cgcaattatc ccgatattta tactgtagta gattaaattc aaatacaaat taatttttag
    13201 gttaaaaaga tgttgaacat tgtaattttc ggtgctccgg gttcaggaaa aggaacgcag
    13261 agcgaacgta ttgtagaaaa gtatggaatc aaccacatct cgacaggaga tgtattgcgt
    13321 gcagaaatca agaacggcac ggaactgggc aaaactgcta aaggttacat cgaccagggg
    13381 cagttgattc cggatgaatt gatgattgat attctggcaa gcgtattcga tagcttcaaa
    13441 gacagcaaag gtgtaatttt cgacggtttc ccaagaacaa ttgcacaggc ggaagcatta
    13501 aagaagatgt tggaagaaag aggacaggat atttctgtaa tgttggatct cgaagttccg
    13561 gaagaagaac tgatggtgcg tctgatcaaa cgtggcaaag actccggtcg tgctgacgac
    13621 aacgaagaaa caatcaaaaa acgtctgcat gtatatcatt cacagacatc tccgctgatc
    13681 gactggtaca agaacgaaaa gaaataccag cacatcaacg gtctgggtac tatggatggt
    13741 atcttcgctg atatctgcga agcggtagac aaattataat aaataaaaaa tatggctgaa
    13801 tcgaattttg ttgattacgt aaagatatac tgtcgctcag gcaagggcgg aagaggctct
    13861 acgcacatga ggcgcgagaa atattgtcct aacggaggtc ccgatggggg cgatggtgga
    13921 agaggaggcc atattatctt gcgcggtaac cgtaattact ggacattgct tcacttgaag
    13981 tatgaccgtc acgcgatggc aggtcatggc gaatcgggca gcaagaaccg aagttttgga
    14041 aa
//
