LOCUS       c00037_gnlPro..        16811 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIFCHCAH_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:29:43
            Original ID  :: gnl|Prokka|OIFCHCAH_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 75743
            Orig. end    :: 92554
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16811
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[85743:90507]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14764
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16811
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16811
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             499..1608
                     /locus_tag="ctg37_64"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
     CDS             1689..2645
                     /locus_tag="ctg37_65"
                     /transl_table=11
                     /translation="LASCSNDDDEMDKYQKIYIRTGVAPGAEMGAAVVVDCVSNSSTAD
                     RSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKCKLLPQDNYTIETSEVVLKT
                     GQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQAVSTSMKTVYIRIYTSVLY
                     TSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDGEINTTWFTWGVANAGECWW
                     NTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGETEWVTYPRVLTFRNFKGADP
                     QYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             2895..4163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_66"
                     /sec_met_domain="MFS_1 (E-value: 4.8e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             4218..5216
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_67"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.7e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(5320..5793)
                     /locus_tag="ctg37_68"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             5863..6861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg37_69"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.7e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             complement(6966..7718)
                     /locus_tag="ctg37_70"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             7906..8454
                     /locus_tag="ctg37_71"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8506..9768
                     /locus_tag="ctg37_72"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVVAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGRWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYLTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_73"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(10731..12959)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_74"
                     /sec_met_domain="Gly_radical (E-value: 2.7e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1166.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYATVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13718..14764
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_75"
                     /sec_met_domain="Radical_SAM (E-value: 4e-10, bitscore:
                     32.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLNFISPNTLSLLTTYYCTAACKNCCFECNQERRGRMSFKQME
                     TYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAHKKGLITRVVTNGYWAVSYEKA
                     LGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRAAAKVDLPCLVNIETNPSSQFS
                     EEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRDTNYNELIKHRYVQRPIISHGC
                     NSLFESIPIDPEGNVYACCGLACRKAKFLKIGNMNTAGINKIYTRQFDDFLKVWAYVDG
                     PKFILNKIAMETGKNIEVNADMHNCEACLLLLNDPSKIEYIKNNISRYISEVVLKYNIK
                     QKKANYEK"
     CDS             14754..15545
                     /locus_tag="ctg37_76"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENFVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKNCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             15578..16042
                     /locus_tag="ctg37_77"
                     /transl_table=11
                     /translation="MERWSLVLKIVLLTTGLMFLLRTFMLQSLQDQIASLLLGTILVSI
                     YIYMLIVIPSFICLEKDQLVIKRVFGKKCIPYSCIKNVFVYDGVQNDVRYFGSNGFLGY
                     IGVMGSTHYGKYYSYVKNPNQQIFILTEKKNYLLSCENRDMFIKDLLIHL"
ORIGIN
        1 aagaatcgga cctaaatcag gtacgggacg gttacttgtg attgatggcg agcctcaaag
       61 tattcatccg gaaaccgggc cttactttga ctatttcatt gtgcaggcat actctaacct
      121 tgcgggtaat tccgacgcta atcttgacag acgtctggct ggtacgattg ccaactttaa
      181 aggaatactt cctccggaga aagtggctaa tatgtacatc gttacggaga atttcgaatc
      241 ttatgctccg acaggaggag gtgattatgt agatcgttac ggaaacaaaa tgagagcact
      301 tgccggtatg gcacgctgga ctccgactat tgacggaaaa caggtacgga aggggggagt
      361 aggcacctat cacatggaat atgactatcc gggcgacatc gaatataagt acctgcgtga
      421 agcaatcaga ataatgaatc ctgctgtaaa atgactttaa agaatttgat tatgaaaaga
      481 ataacaataa aacaatgttt gcttgcctgt ttcgttctgc cgatgatcct ggcaggatgc
      541 aacgatgccg attaccaggt tatcgacaat gcgatttatt tgaatgaagc atccgagaat
      601 ggttcggcaa aggttaccgt tgatcctgaa aatgtaacaa caactactct gaccgtacgt
      661 gtgggacagc ctgtaaccga aaatgtgact gctgtcctga cggtagatcc ttctattctt
      721 aaagagtaca atgaagctaa tgaaacttcg tacgaagtcc ttcccgagca gtattttact
      781 tatgacaaag agataaagat agcggcaggc gatgttagcg caatccccag tgagtttaga
      841 gtgaaacctt attcaaacga aaacggagaa ttgtatgcta ttccggtgtc tctcacagaa
      901 attcagggac cggtgtccac aatcgggctt tcgtcgaagt ttatcatttt gctggataag
      961 ccgctgatac agtctgtacc gtttatgaat acgaccaatg ccgtgaagcc cgccaaggac
     1021 gaattgtggg gagtgacaac caatgaatgg tcactcgagg cttgggtaca gatggacgga
     1081 ttcgatatta ataatcaggc tatatttaat tcgggcagca gcgaccacga ggtttatatc
     1141 cgtttcggtg acgctatgat cccttataat tcattacagg tgaagacact tggaagtcag
     1201 gtcaatacgg tgactttgtt tgagaagaat aagtggtatc atctggcctt cgtttataat
     1261 tcttccgggt tattgtcgat ttatatcaac ggagtgctcg acgtgactct gcagacaaag
     1321 ggtggcccgg ttagattcga caagatgaac atggtttcga gcggtagtta cttccgcaac
     1381 aattgtcaga tggcccaggt gcgtctttgg aagagcgcaa tcagccagac gcaaattcag
     1441 tccaacatgt attttgccgt gaaacccgcc gatccgaacc tgataggcta ttggaaaatg
     1501 gatgaaggta agggaaatgc ctttgccgac tgtaccggac acggatacga tttggtggca
     1561 ggaggaactc ttgtctggaa agagcatgtt cgttttgata agcaataact atgtaaaaag
     1621 aagataagat atgaatagac atttgaattt tgtgacctta atctggcctg ataacaggct
     1681 ttgtatcgtt ggcttcgtgc agcaacgatg atgatgaaat ggacaaatat caaaagatat
     1741 atatcagaac gggagttgca ccgggggccg aaatgggtgc tgcggtagtg gtggattgtg
     1801 tgagcaattc ctctactgcc gaccgttctg attttgaaat acaattgtgt gccgtacagc
     1861 cggttacgcg ggatgtcact gccgctttgg gagtagatac gctgaaagtg gatacttaca
     1921 attctgccaa taagacgaaa tgtaagttgt tgccccaaga taattatacc attgaaacaa
     1981 gtgaagttgt cttaaaaacg ggacagacag tggccgattc atcttttcag gtcgttttga
     2041 agaatataga aaagttgact aatcctgacg gatatgtgct tcccgtgacg cttaaaggag
     2101 ttacgggcat ggacgaacag gctgtcagta catctatgaa gacggtttat atccggattt
     2161 ataccagcgt gctttatacc agttatacga aacccgggaa ttggtccgct gtagatcgaa
     2221 gtgcgtggag tgtaagttgc agcaatgttt atgccgatga tgatgccaaa tatggtgcac
     2281 atctggctat tgacggtgag ataaatacta cttggtttac atggggagtg gctaatgccg
     2341 gagagtgttg gtggaatacg gtactggacc ggcctgttac cttaaccgga ttttcggtca
     2401 ctaaacagag tgcctacgga tcgggttata atctgagaag tgctgagatt aaggttcgga
     2461 aagagggtga aaccgagtgg gttacttacc cgagagtctt gactttcaga aattttaaag
     2521 gggctgatcc gcaatatgcg gccatcgaac cacctatccc gaatgtaaag gaattcagaa
     2581 taaactgtct gactccggat aattataccg ggtttgctga gataaattta tatgtgaagc
     2641 aatagaggtg tttagattgt agataagggg gcgagaggca tcggggatga aagtcttcgg
     2701 tgcttctttg cgtgtattgt attgataaag tttaataaaa aaagggtgat agaggttagt
     2761 agttttcccg ggtgagttgt attattaaat aatgaaagca acttcttgtc gtaatcttgg
     2821 gttatgtttt taatatcccc tatctttgct tactggaatt gttaaccgat ggaattatta
     2881 taaaaaacta actgatgaat aaaaagccga taagccctgt atgttgggtg cctactgttt
     2941 actttgctat gggattgccg tttgtggccc tttcgatggt ttctgtcctt atgttttccg
     3001 atatggaagt gtcgaatgca cagattgctt tctggacttc tctcattatg cttccctgga
     3061 cattgaagcc tttatggagt ccgtttctgg aaatgtttaa aacgaaaaaa tactttgttg
     3121 tcgctacgga aatcattacc ggactggcat ttgcattggt agcactttcg ctgccgctgc
     3181 ccgacttttt tcgttatgcc atcgctctga tggggatcat tgctctcagt ggtgcgactc
     3241 atgacattgc gggtgacgga gtatacctga ctgaactgac tgctacccag caagccaagt
     3301 atatcggttg gcagggagct ttttataatc tggccaagat acttgccaac ggaggcttgg
     3361 tttggctggc aggtatgctg aaggatgaat ttggagtggt acatgcctgg atgattgtca
     3421 tgttgatgtg tgcgggtatt atgattctga tcggtcttta ccacatccgg attttgcctt
     3481 cgggaggagg cgcttccggt gaagtgaata cgatgagtga cgcattgaat atgctttggg
     3541 aagtcatccg ctcttttttc caaaaaaaac atattgcttt ctacattgtc tttatcattt
     3601 tgtaccggtt tgccgaagga tatgccatca agattgtacc gttgttcctg aaagcgtcgg
     3661 ttgcggatgg tggattggga ctcagcactc aggatatcgg actggtatat ggtacgttcg
     3721 gagcgggagc ttttattctc ggttcgcttt tggccggtta ttacatttcg gctttcggac
     3781 ttcggaagac tttgttttct ttatgttgcg cttttaatat tccgttcttg gtatatttcc
     3841 tgttagccct ttaccagcct tccgatctat ggattattgg tatggccatt gtgtctgaat
     3901 acttgggtta cgggtttggt tttgtcggat tgatgctctt tatgatgcag caagtggctc
     3961 ccggcaaaca tcagatggca cattatgctt ttgctaccgg tattatgaat ctgggggtga
     4021 tgcttcccgg aatgatgagc ggatacctga gcgattggct gggttatcgc gatttcttta
     4081 tctgggtact tatcgctacc ataccggctt ttatcgtgac ttggctggta cctttcacat
     4141 atccggacgg aaagaagaaa taaaaagaga ttttcaatat aaacaagata tatacataat
     4201 attaatttaa tcgaatcatg gaagaaatta aaattgcagg tgctgctttg ccggctatgc
     4261 cttgggaaga acgtccggca ggatgtaaag atgtagtgtg gcgttgttcg gccaatccga
     4321 ttattccgcg cgacttgctc cctacttcaa acagtatatt caacagtgcc gtagttccgt
     4381 ttaaggatgg ctatgcaggg gtgttccgtt gtgatgatac taatcgtcgc atgcgtttgc
     4441 atgtgggatt cagcaaggat gctgttcatt gggatatcaa cgaagaaccg ttaaagtttc
     4501 aatgtgatga tgctgaggtt ggaacctggg tctatggata tgacccacgg gtttgcttta
     4561 tcgaagaccg ctactatgtg acctggtgta atggctatca tggtcctact atcggtgtgg
     4621 cctacaccta tgattttgtt acttttcacc agttggagaa tgcctttatt cctttcaatc
     4681 ggaatggagt cttgttccct cgtaagataa acggtcgttt tgcgatgttg agtcgcccga
     4741 gtgataatgg gcatactcct tttggagata ttttctatag cgagtctccc gatatggagt
     4801 tttggggacg tcatcgtcat gttatgtcgc cggctccgtt cgaagacagt gcctggcagt
     4861 gtaccaagat cggtgcaggg cctatcccga ttgaaacctc ggaaggctgg ttactgatct
     4921 atcatggtgt attggcttcc tgcaacggtt ttgtgtatag ttttggttcg gcactgcttg
     4981 acatcgatca gccctggaaa gtaaaattcc gttcggggcc ttatctgatt tcacctcaga
     5041 aggattacga atgtatgggt gatgtgccta atgtctgttt cccatgcgcg gcgcttcatg
     5101 attcggagac cggacggatt gccatctatt atgggtgtgc ggatacagtg accgggctcg
     5161 cattcggata cattccggag attattgaat ttaccaaacg tacaagtatc atctgaatcg
     5221 aataaaacag gaagggtgta gctatcccgc cgggatggct acaccctttt gtttgtatgg
     5281 ctacaccttt tcggtcagat ggctacaccc tttcggctgt tatccgttgt atgcagtcag
     5341 catccaaacc atcttttcct gttctttcag gtagtcgctc atcatggcca ctgttacttc
     5401 gtcgttgtgt gaagaggcga gagacaggat tttacgttct tccgcaatca gatgcccgta
     5461 agtttcgaga atatgattca gagcgtcgtc ggccttattc actccgtcca cttccttgat
     5521 ctgcgccatc ttcagatagt cactgtattt attggcggga gttcctccca gcatcagtat
     5581 acgttcggct atttcgtcca ccttttcggc ggctccatta tataaatctt caaacttgct
     5641 gtgcagtacg aagaaaccgt gtcctttgat gttccagtga aatcctctca ggtttgcata
     5701 atgaatctga aaatcggcaa gcagttgctg taatgacagt acgatggtgt tagctccttt
     5761 ttcttccaaa tgtgtataat ttaaagtctt cataatgata ttgttttttt tgagttaata
     5821 ctatatttct tctttttatc tggaacaaag atacggcaca aaatgattcg tgtcaaactg
     5881 aaaatttcta tctttgcatt gatagattct atatctttaa taaatcagag aacgatgact
     5941 atacaacaat tggaatatat tctggctgtg gaccagttcc ggcattttgc taaagctgcc
     6001 gagtattgcc gggtgacgca acctactttg agtgcaatga tccaaaagct ggaagacgaa
     6061 ttgggggtga aactgttcga ccgtagcatg acaccggttt gccctactgc cattggtaag
     6121 aaagtgctgg aacaggcccg taagattctt tcggaagtta tctgtgtcaa ggagatcatc
     6181 agcgaagaac agcactccct gtcgggtaca ttccgattgg cagtgttacc gacgattgca
     6241 ccttatcttc tgccccgttt ctttccgcaa ctgatggaga aatacccgga tcttgatata
     6301 cgggtgatgg agatgaagac gcccgacatt cgcaaggctc tgctgaccgg tgaagcggat
     6361 gctgctatca ttgccagcat gctggatgat gccgcattaa cggaagagac cttattctac
     6421 gagcaattcc tgggctatgt ctcaaagaag gaaccgttgt tcaagcacga tgtgattcgt
     6481 acgtccgatg tgacagggga acggctttgg cttcttgacg aagggcattg cttccgcgat
     6541 cagttggttc gtttttgtca gatggaagcg gttaagatca gccaaatggc gtatcggctg
     6601 ggtagtatgg aaacctttat gcatatggtg gagagtggta aggggattac gtttattcct
     6661 gaactggcag tgatgcaatt gagcgaagag cagaaagaac tggtccgtcc gtttgctatc
     6721 ccgcggccta cccgtcagat tgtcctggtg acccggaaag acttcatccg caccagtctg
     6781 ctgcaggttt tgaaagagga gattcaggcg gcggttccca aggagatgct taccctgcag
     6841 gccgttcagt gtctggtata atataaaaac gacggcgata ttttcacaaa catcgccgcc
     6901 ttatttcttt tatgtatcag aattattact cgttttgcct gattgtgtag gtgtttcttg
     6961 ttgttttatt gagaatgaaa tgattttatt tttaagtttt tgtcttcgtt gatatctatt
     7021 gtgacatact gtatattgtc ataaatggtg ttcacacgga gttttattcc tttggctgtc
     7081 gccaattgct cggctatact atccagcttg aaagaaacaa ggctcgaacc caattgattg
     7141 ggggagtcat taaaggcatt atgccggaac tccagataga tatatccgtc atcttttatg
     7201 ggacctgtta tttcgttttg taccaagttc agcatgtgtt ttttattttc attcatgctg
     7261 cccagatatt gatattcgat ggtcagataa tctttcgtaa gtgcatgcgc tgtgacgttg
     7321 atacggtcgt ctccaatgct gtctgctgta gcttccgtca gtggaatgat ctctttcgtc
     7381 aatatatctt ctatcgtgaa tattttaccg ttctcatatc cgggcttctc ttttcccatc
     7441 tgcagatagc caacgaagac tctttgacct tctgcaacag tgtatttcct gttgcgtata
     7501 tcggccgtat ctgccggaag tacattgtct ccattgtcca acgcaatgaa aaagtccctt
     7561 ggagtgtccg cattgggaat cttcattgtg ccgatggcta atattccacc cggaggacaa
     7621 gtgacccact cgtcgttgtt ggcatcgtcc agacatgact gtaaaatggg caataacatc
     7681 aggatgacgg caaaagttat taaattaaat ttcttcataa gtttcttgtt ggttttatcc
     7741 tatttatcca ttgagattta ttctttattg tattgagaaa atgcaggaag tgatgaaata
     7801 ttgcatccta aaatgttaaa gaaacaaaag tgataaaaga gttgttctct ctgtgcagta
     7861 tttctatctt tgctgcattt ataaggtaaa cacgtgttta ggagaatgaa tgaattagag
     7921 ctgtcggaac gttgcaggca gggagataat cgtgcccgca aagaacttta tgagcagtac
     7981 gcagggcgca tgcttggtgt ctgtcttcgt tatgccggag acagggacat ggcacaagac
     8041 ttggtacacg acggtttcct gaagattttc gactccttcg acaagtttac ctggcggggt
     8101 gaaggctctc tgagagcatg gatggagcgt gtaatggtga atacggcttt acagttctta
     8161 agaaagaacg acgtgatgaa ccagaccacg gcactggatg aagttcccga aacgtatgaa
     8221 gaaccggatg cttcggctgt tgaagcaata ccacagaaag tgctgatgca atttattaat
     8281 gaactccccg ccggatatcg taccgtattc aatttataca cctttgaaga taagtcgcac
     8341 aaggaaatcg cacagatgtt ggggattaat gaaaaatctt ctgcctcaca gctttttcgc
     8401 gcaaaaagtg tattggcaaa gaaagtgaaa gaatggttgg tgaccaatgg ttgacatgta
     8461 tttacagata ctgaggtgaa ccttggattt caaaaatgaa atagaatgat gaaagaagac
     8521 gaaaaatgga ttaaagcatt caaggataag ctcgaagatt attcggagcc gatgcctgct
     8581 tccggttggg aacgactgga aagggaactg atgcctgtaa ccgaaaaacg aatatatccg
     8641 tatcgccggt gggcggttgt tgcggcagct gtggtattgg tggtaacgac tgctgtcagt
     8701 ttgtattttc tgaatagtcc ggtagctgat gaaatccgtt atgcaacggc tccttcactg
     8761 gctgtcaacc cggatgtatt gccggaacct gccttgccgg atgtacaggt agctgtatcc
     8821 gaacccgtta agccggtagg aacgacgagt atcaaccctg tttcgggcta tttggcaaag
     8881 aatactgatc cggtgattgt tccggaggta tcctccttgg cagagaagcg accggaggca
     8941 gtgacggagg aaaagagagc tgagccgcaa caggaagcaa ctgctgcaat cgagaaaaaa
     9001 gaaagtgcga cagcgcagcc tccaaagagg aaagaagcgc ggcgaccgtc cggtaaagac
     9061 aagtatcagt tgcctatcgg agactcttct gctaaacgtg gtggtagatg gtcgatggga
     9121 gtgggtatcg gtaatggagg tggacttccg acaaatggtt ccgaaaattt tgcgccccgt
     9181 ccgatgacta acagggtcga cttgatgacg atcatgaatg gagctgtgag tattcctgcc
     9241 gatcaggaag ttatatttga agaaggggtc ccttacctga agtccaatac aactgccgtg
     9301 gtggattatg aacatcatca gccggttagc ttcggactgt ctgtacgtaa gtctcttccc
     9361 aaaggtttct ctgtagagac gggattgact tatacgttgt tgtcttctga catcaaacgg
     9421 cagggggata ccaagatgca gagtcagaaa ttgcattata taggtattcc tgtacgtgga
     9481 aactggaatt ttctggaaaa gaaatatttg acactctatg tatctgccgg aggaatggtt
     9541 gaaaagtgtg tttatggaaa gttggcggat gataaggtga atgtgaagcc tttgcaattt
     9601 tctgtagccg gtgccgtggg agcgcaattc aatgcgacag atcatgtcgg cctatatgtg
     9661 gaaccgggag tttcgtattt ctttgatgat ggctccaaag tacaaaccat ccgaaaagaa
     9721 aggccttgta actttaactt gcaggcagga ttgcgattca cttattaaag taggatggca
     9781 aaaaatatgc cggttacatt atctccctgt tcttgccttg tattgtaatg aattaaggca
     9841 agaacaggga gacttttata tcgtgactta caaaattata aataagtgca gtcgtcataa
     9901 ttcaccgcag aatgaactta atctgttgat tgccaatgaa tctttatctg tgtaaattcg
     9961 tgtaatctgt ggcgaatacg aatttcgaca cttatataag tcaattcact tgtacggtcc
    10021 ggaagtattg cctgaatagt ttttcagcct tttctatctg ctctggagta ttctctttca
    10081 ctcctttcag catatattct ttgttcattg cttcatattt gtgaacaccc aaggtgtggt
    10141 aaggcaatat ttctacacgc tgaatcatct ggtacgttcc aagatgctct cccagctgcc
    10201 ggatatcgtc ttcgaagtca ctgtagccgg gcactaatac gtatcgcaac cagaatggtt
    10261 tatgattggt ttcaagccag gctgcggttt tcagggtctg ctcgttgctt cttccggtta
    10321 aagactgatg atgttccgga ttaaattctt tgatatctaa taaaaccaga tcagtcaatt
    10381 ccaatagttc ctctacatca ttgttccata gcccgccatt ggtatcaagg caaatatgga
    10441 ttcctgcttc ctttagtctt ttaaaaagtg ggataagcga ttttgcttga aaagtaggct
    10501 ctccgccgga aaaggtgata cctccctttt taccgaagaa agctttctga ctgacggcca
    10561 tgcgaactat ttcctcagga tcggttgctg tccctccttt ggcttcaatt gtgtccggat
    10621 tggcacaata gaggcaacgg aagttacacc cttgaaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccatt gactcgtatg agtgtacgtt tatcattcaa ttacattctt
    10741 tcgtggaaac tgcggctgat tacttccaac tgatgttcgc ggctcaattt cacgaaatta
    10801 acggcatatc ctgagacacg gatagtcagt tgcggatact tttcgggatg ttccatcgca
    10861 tcctgcaaca tttcccggtt cagcacgttt acgttcaggt ggtgtgcgcc ttttgtaaaa
    10921 tatccgtcca tcatggtcac cagattgtcg atacggtcct cttgtgttgc tcccaatgat
    10981 ttgggaacga tcgagaatgt attgctgata ccatcctgtg agtcgcgata acgcaacttg
    11041 gctacagaac tcagtgaggc gattgcacca tttttatcac gtccgtgcat ggggttggca
    11101 ccgggagcaa aggcaatgcc tttggcgcgt ccgtcaggag tggcaccggt cttcttgcca
    11161 tacattacgt tcgaagtgat agtcagcagc gaaagggtag gacgggcatt cttatatacg
    11221 gggagtttct ttaattcttc gctaaagaaa tataccaggt ccacacccag gtggtctaca
    11281 cggtcatcgt cattaccgaa acaagggaaa gcaccttcga tatcgaatcc ctccgtcagt
    11341 ccgatgtcgt tgcgacgggc tttcacatgt gcatatttga tggcggacag tgaatcgatg
    11401 gcgattgaaa gtccggctac accataagcg aggttaatgc ggggatcagt atccacgaaa
    11461 gccatctgtg ccttttcgta gtaatactta tcgtgcatgt aatgtatgat attcattgct
    11521 tcgttgtata cacgtgcaat ttgtatcaat actttcttat agttggccat tacttcttcg
    11581 aacttcagtg tttcaccggt caatacaggg atgtctttta ccataactgt acctgtattt
    11641 tcgcaacgtc ctccgttgat agccagtagc agggctttgg caaggttggc acgtgcgccg
    11701 aagaactgaa tctgctttcc gatttcctga tatgaaacac aacaagcgat tccgtagtca
    11761 tccgattgac ggacttcacg catcaggtcg tcgttttcgt attgtacgga agaagtgtcg
    11821 atagatactt gtgcacagaa tgctttgaaa ccttcgggta actcagggct ccatagtaca
    11881 gtcatgttag gttccggtga cgggcctaag ttataaagtg tctgcaagaa gcggaaagaa
    11941 gttttagtaa ctttggtacg tccatcattg aaacgtccac cgatagattc ggtcacccat
    12001 gtgggatcac ccgcaaaaat atcgttgtac gactgcatac gcaagtggcg taccatacgg
    12061 agtttgataa cgaattggtc gatcagttcc tgagcgaatg tttcggttat cgtaccctgg
    12121 cttaattcat attcaagata gatgtcgagg aatgaagata cattacccag tgacatggca
    12181 gcaccatcct gctcttttac ggcagccaga taagccatat acacccattg tacagcttcc
    12241 tgtgcggtat atgccggtcg gctcagatcc aaaccataat attcgcccaa tactttaatc
    12301 tctttcaggg ccttgatttg ctcggctact tcttcgcgaa gacgaatgcg ggcttcagtc
    12361 ataggacctg tcagattatg cagatcttct tttttagctt ctatcagacg gtcaagacca
    12421 tagagagcca ggcggcgata atcaccgatg atacgtccgc gtgcatagtt gtcgggaagt
    12481 ccggtaagga atcccaatga acggaacgaa cgaatttctt cggtatacac atcgaatacc
    12541 ccatcattat gagtcttgcg atagtgagtg aagatatcct taactctgtc atctacttcc
    12601 actccgtttt cacggcaagc tttcataacc acattgattc cgccaaacgg tttgatggca
    12661 cgttttaaca cctgatcggt ctgtagtccg acgatcagtt cgttttcttt atcgatgtag
    12721 ccggcagggt gagaggttat agtagataca gttgcgtagt cgagtgcacg aataccatta
    12781 ttgtttctct cttcttcgag agctttgaga cagtgattcc agacagcttt ggtgcgttcg
    12841 gtaggtcctt gcaggaaaga agcatcccct tcataaggag tgatgttatt actaacgaaa
    12901 tcccttacat tgatttcttt gctccaaagt ccatctttaa aggtcttatt cagttccata
    12961 aaattaatca gttagtggtt agttatcctt tagagcgcgc aaatttacaa ccttttttcg
    13021 gtttaggtat ataaaagggt cctattttat gttgaatagc ataaaaatac ctatttatgg
    13081 ggagaagcca gatagcagtt atcacttcca aatatacttt tctaatattt ttttgcggaa
    13141 taatttgcaa gttaaaaaat gattcgtacc tttgcagcgc tttaagagaa aagcactact
    13201 taaccgtagt tctggagagg tggcagagtg gtcgattgcg gcggtcttga aaaccgttgt
    13261 actgcgaggt acccggggtt cgaatccctg tctctccgca ataaacattg ataatcagtt
    13321 gtttacaaga ataacaccca attttacacc ctgaaaagta aaattgggtg ttttgtatta
    13381 tttaagattt gtttcttgct gttccgtatt taattattcc aactggaggc tattctaaat
    13441 ttcctgctta tgcagtgtgt ctatagaggg ctaataatta tatatttttt gttttgattg
    13501 aatctgtttc tacaaatgta gaatgtgagg gctatgaatg ctacttcctt tctaatctaa
    13561 taaaattata attttgtaaa ttgttattca cattgataaa attgtataat tagattaaaa
    13621 tttcgtgttt aaccgtttgg atgtaacaaa aataaagtat atttgccata taagtaatat
    13681 tttgaaagag tttaagctct taagtgaata attagccatg gaattactga attttatatc
    13741 acctaatacc ttatcattgt tgacaactta ttattgtacg gcagcgtgta agaattgttg
    13801 ttttgagtgt aaccaagaac gtagggggag aatgtcattt aaacaaatgg aaacctatat
    13861 atcggaatgt gtaaaagctt tccctacgat taggctggtt gtctttagtg gtggagaatg
    13921 tttttcctta aaagatgatt tatatcaagc tatttattat gcacataaaa aggggcttat
    13981 aacaagggtt gttactaatg ggtattgggc tgttagttat gaaaaggctc ttggaatttt
    14041 ggtgttacta aaggagttgg ggttaaatga attaaattta agcacggggg atgatcatca
    14101 aaaatgggtg ccctttgata atatcgtaaa tgctataaga gcagcagcta aagtggattt
    14161 gccttgtttg gtgaatatag aaacgaatcc aagttcacag ttttctgagg aagatttcaa
    14221 aaatcatgaa gagttaaaag agtatatacg ggataataaa gttatctttt cttctggtat
    14281 atggattcca tttgatatgg aggataaaat taaacgtgat acaaattata atgaattaat
    14341 aaaacataga tatgtgcaga gacctataat atcccatggg tgcaacagtc tatttgagag
    14401 tattcctatt gatccggaag ggaatgtgta tgcttgttgt ggactggctt gtagaaaagc
    14461 taagttttta aaaattggaa atatgaatac tgccggtata aataaaatat atacaagaca
    14521 atttgatgat tttttaaaag tatgggctta tgttgatggg ccgaaattta tattaaataa
    14581 aatagcaatg gaaaccggga aaaatattga ggttaatgct gatatgcata attgtgaagc
    14641 ctgtctattg ctgttgaatg atccctctaa aatagagtat attaaaaaca atatatccag
    14701 atatatatct gaggttgtat taaagtataa tattaaacaa aagaaagcga actatgaaaa
    14761 gtaaaattct aactttaggt gttggagcag caatagctgc tacttcattt tcttcatgtg
    14821 ataattcaaa tgattttcct aatttagcta ttgcgtcaga agaaaatttt gtagatgatg
    14881 aaactactgc tatttctatg aaaaagttat cacaggagga acaggtgtat attcacgata
    14941 tgagtttatt atcacataat attttaaatg atacaaatgc agcggaagcc tttttgaatg
    15001 cccctttgga atatgcccgg tctttgggaa taaaaagctc tatagatact gatgacggta
    15061 ctgtacgttt tttattagca atttgtaagc cggaatttcg agaggctgta ataaagagag
    15121 atattagaag atttgtagaa ttatgtgaaa agtatgatat ttttaaaaat gccaattctt
    15181 ccaatattaa attattgaac catactgcaa taacaagaag taaaaactgt gtagatgtgc
    15241 aaatgggatt cttttggatc ggtgaatgga ttttgttagg tgttgcatat gttggggcag
    15301 gaattgatta tgcagcactt ggtggtcccg tagtatgtgc ttccagaaca attaacagtg
    15361 aaatggcatt gcaggtttgg gacgttgaaa cacaggacgg aagtgtatat gagttagcag
    15421 atgagtacaa aaatcactat gttcaagatt tggttaagtt agtaaaagaa aaacgtcctg
    15481 aggttatgga acgatatacg gataaagaac ttattgaaat aatacagaag acattagcaa
    15541 tataatgagc gtatataaat caaaatttca gccggtaatg gagcgttggt ctctggtatt
    15601 aaagattgtc ttattaacta ctggccttat gtttctatta agaactttta tgctacaatc
    15661 tttgcaggat caaatcgcaa gcctgttatt gggtaccatt cttgtatcta tatacatata
    15721 catgctgata gtgattcctt catttatttg tttggaaaag gatcaactcg ttataaaaag
    15781 agtgtttggt aagaaatgta ttccgtattc ttgtattaag aacgtttttg tttatgacgg
    15841 tgttcaaaat gatgtccgtt atttcggaag taatggcttt ttggggtata taggtgtaat
    15901 gggcagtacc cattatggga aatattattc ctatgtaaag aatcccaatc aacaaatttt
    15961 tatattaaca gaaaaaaaga attacctctt aagctgtgag aacagagata tgtttataaa
    16021 agatttgttg attcacttat aatatgctgg atattaatat aacctgttgg aaaatatagt
    16081 tatagtatta cttgacggga agaatatgtt ttttattctt cccgttagtt ttttagagca
    16141 ttaataatta aaccctgtat ctctgcaata aatgttgaaa atctgtgaat tacaagagta
    16201 atacccaatt ttatacccta aaaagtaaaa ttgggtgttt ttgctttatt taatactttg
    16261 ttcttttatt acttgttggg ctttgcactg tctttggttg cttagctatt atttattgta
    16321 taatttacaa aggggatatt gtatcgttga tgacattgtt atactaatat ttatttatgt
    16381 cattttattt tttttacatt tttagagtgg gaaatctccc gaataattct gtcttttata
    16441 atagtaatac attcctttaa aggttgattt tgtgttattc tgtttgtatc ttttggtact
    16501 aaacgcatta tttatattgg ataggcattt aggttatgaa ttgaatataa cttttggctt
    16561 ttaaagtaca tttcattttg tcaatgaaat actaattaat agttatttta ctgataaaga
    16621 aatttgtatg attttgcata aatacatatc gcaaagatgc aaaaacgatt tattttattg
    16681 tgttgatagt ggatttgttt acagctcttg tatgttatac ttttattttc atgctttggg
    16741 tataatgata acaattaata tgtatagaaa ggtgactaca ttaattaatt ttgcagcatt
    16801 tgttttattt t
//
