LOCUS       c00018_gnlPro..         6081 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EKNFDBHH_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:17:12
            Original ID  :: gnl|Prokka|EKNFDBHH_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6081
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6081
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2749:6079](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2750..6079
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..6081
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6081
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(177..1376)
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARQMASELALLPMWYA
                     EEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLD
                     LGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESH
                     DTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGKQQGGVIGEPLYNKVEDFAMEFRS
                     SSNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLEQELSL
                     RFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAF
                     QISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL
                     "
     CDS             1539..2717
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2750..6079
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="PFOR_II (E-value: 1.5e-19, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.7e-83, bitscore: 267.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.7e-32, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.6e-13, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 6.2e-13, bitscore: 37.4,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.9e-10, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.9e-06, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3e-26, bitscore: 78.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYN"
ORIGIN
        1 gtaaactaac ttaggtataa caagcgaagt tgtcaactaa atccagtaca gtacacacat
       61 ggcatgtgat tacttgtttc atgcaatgaa actttttgtt tctcggtgtg gaaccaatgg
      121 tttcactaca tgaaactatc agtttcacac cgagaaacca taacttcgat ataatatcac
      181 aaaaacacgc tttttgagat aaacacccac gcccgataac tactcttttt atgagccggc
      241 accaatgaca aatagcctga ttttattctt ccttgttcta tttccaaagg ataagcctcc
      301 tccatttctt tgtgtgctct ccaggctgtt ccttccgtag ggtaatagct tatttgaaaa
      361 gctcctgttg aagtaggata gatataatgg tcataaatat gacgcgctac tactcccata
      421 ttcatcctca agttgatttc cacgcaagga tgaatccgat aaacaggaga ttctggaaag
      481 cgacagatca tcatatccac tcccaaataa ccattataaa tggttccgaa acggagggat
      541 aattcttgtt caaggcggtc gcgcaattta taaatttctt cgacagggat atattccaaa
      601 agattccgtt cgatggctgc atctgaaatc agcagattac cttcgtacgc cccacttcca
      661 cccgtacgga attgagagta tccggcaaag ccaaatcgac cattactcga agaacgaaat
      721 tccatagcaa aatcttccac cttattatat agaggttcgc caataacacc tccttgctgt
      781 ttgccaatgc gtgagcacca accggaaata gaaggagtat atacaccttt gcaccagttc
      841 agccctttcc cgctaccgga taaaggagct ttcagtaaac aagtatcatg tgattctaca
      901 aatgacttcc attcttcggg aaacgtcagg taaaaagact ctccacaaaa acaggctccc
      961 agttgtagct gtggtaataa tcccacagcg caggaacgat gggaacagaa acgcagttta
     1021 tccaattgct caatagaagg aagctcgctt tcttccactc ccaaatccaa cagtcgtttt
     1081 cttattgcta tatcccagcc ccaaggacga atatccaaat tccgctccga agcaagttca
     1141 ggttctgtca tcaaatcaac cgaaagtcct aataattcct gtatcttctt cacatagtcg
     1201 agattataag cggaaggagc caatacaaca cttccctctt ctgcatacca catcggcaac
     1261 aaagccaatt cggatgccat ctgccgggcg gaagccggtg ccatatagtt tgtttcaccg
     1321 ctggctaacg ccaaatcatg ttccggattg aatatataaa gagccttttt tgtcatttta
     1381 aacgaattca aaactttatt ctgcaaatat atacaggaaa tagtcaggaa tggctacaat
     1441 aaacagaaag ttctaattaa actcacaatt ttgccatctc tactttgcaa atcctaaaaa
     1501 aagcagtata tttgccaccc gaaaaacaaa gaactgaaat ggaatcattc tatcgcacac
     1561 acgcctacct cgttgagcac accaatgccc ccgttcgccg cgatcttatg gacgagatcg
     1621 actggagcga ccgcctgatt ggtatcaaag ggacacgtgg cgtaggaaaa accactttcc
     1681 ttctccaata cgccaaagaa aaatttggga acgaccgctc ctgcctgttc atcaacatga
     1741 acaacttcta cttctctggc cacagcattg tagactttgc taacgaattt cagaaacgtg
     1801 gcggaaaagt attgttgatc gaccaggtgt tcaaacatcc ggaatggagc aaagagttac
     1861 gcatgtgtta cgaccgtttt cctaacctga aaattgtctt caccggctcg tccgtgatgc
     1921 gactgaaaga agaaaatctt gaattacgtg atatcgccaa gagctataac ctgcgcggat
     1981 tttcttttcg cgaatacctg aacttacaga caggcatgaa attcagggca tacagcctcg
     2041 aagaaattct tagcactcac gaacagattg ccaaaggagt actctctaaa gttcgtccgc
     2101 tggattactt ccaggattac ctgcatcatg ggttctatcc gttcttcctc gagaagcgta
     2161 acttctcgga gaatttgctg aaaacgatga acatgatggt ggaagtagat atacttctca
     2221 tcaaacaaat tgaactgaaa tatctttcaa agataaaaaa attactatat ttgctcgctg
     2281 tcgacgggcc gaaagctcca aatgtgagcc aactggcaag cgacatacag acatctcgcg
     2341 ccacggtgat gaactatatc aagtatctgg cagatgcgcg actcattaat ctggtttatc
     2401 cgaaagggga agaattccct aaaaaacctt cgaagataat gatgcacaac tccaacctga
     2461 tgtattccat ctacccggtg aaagtggagg agcaggatgt gctcgacact ttctttgtga
     2521 attctttatg gaaagaccat aaggtacata aaggagataa aaacgtctct tttatggtgg
     2581 acgaagtaat gccgttcaaa atttgccagg aaggagcaaa gatcaagaac aatccgaatg
     2641 tgacgtacgc gttgcataag gctgaaatag gtcggggcaa ccagatacct ctctggatgt
     2701 tcggcttttt atattaaaag atttatttac ttaaatattt aatttagtta tgactaaaca
     2761 gaagaaattc atcacttgtg atggtaacca ggctgcagcg catatctcgt atatgttctc
     2821 tgaagtagct gctatctacc ccatcactcc ttcttcgact atggctgagt acgtagacga
     2881 atgggctgcc gcaggacgta agaacatctt cggcgaaaca gtattggtac aggaaatgca
     2941 atctgaaggt ggtgctgccg gtgcagttca cggttctctt caggctggtg cgttgactac
     3001 tacttacact gcttctcagg gtcttctcct gatgatccct aacatgtaca aaattgccgg
     3061 tgagttcttg ccttgcgtat tccatgtatc tgctcgtaca ttggcttctc acgcattgtg
     3121 tatcttcggt gaccaccaag acgtaatgtc agctcgtcag actggctttg cgatgttggc
     3181 tgaaggctct gtacaggaag ttatggattt ggctggtgtt gctcacttgg ctactatcaa
     3241 atctcgtgtt ccgttcatga acttcttcga tggtttccgt acatctcacg aaatccagaa
     3301 gattgaaatg ttggaaaatg atgatcttgc tccgctgatt gatcaggaag ctttggctga
     3361 attccgtgcc cgcgcactga atccgatgaa tccggttgct cgtggtatgg ctgaaaatcc
     3421 tgaccatttc ttccaacatc gtgaatcatg caacaactac tatgaagcag ttcctgctat
     3481 cgtagaagaa tacatgaatg aaatttctaa gattacaggt cgtaaatacg gtttgttcga
     3541 ttattatggt gcagaagatg cagaacgcgt aattatcgct atgggttctg taacagaagc
     3601 tgcccgcgaa gctatcgacc acttggtagc aaatggcgaa aaagtgggta tggttgccgt
     3661 acacctgtat cgtccgttct ctgctaaaca cttcctggct gctgtaccta agactgccaa
     3721 gactatcgca gttcttgacc gtactaaaga accgggcgct aacggcgaac ctctttacct
     3781 tgacgttaaa gactgcttct acggcgcaga aaatgctccg gttatcgttg gcggtcgcta
     3841 cggtttgggt tcaaaagata ctactcctgc tcaaattctt tcagtattcg agaacttggc
     3901 catgccaatg ccgaagaatc acttcactat cggtatcgta gacgacgtta ctttcacttc
     3961 tcttcctcaa aaagaagaaa tcgctttagg cggtgaagga atgttcgaag ctaaattcta
     4021 cggtttgggt gctgacggta cagtaggtgc taacaagaac tctgtaaaga ttatcggtga
     4081 caacactgac aaacactgcc aggcttactt ctcttatgac tctaagaagt caggtggttt
     4141 cacttgttct cacttgcgtt tcggtgatac tccgatccgt tccacttatt tggtaaatac
     4201 tccgaacttc gttgcttgtc acgttcaggc ttacctgcac atgtacgatg taactcgtgg
     4261 tttgcgtaag aacggttctt tcttgctgaa cactatctgg gaaggtgaag aactggctaa
     4321 gaacctgcct aacaaggtta agaaatattt tgcacagaac aacatttccg tatactatat
     4381 caacgcaaca cagattgcat tggaaattgg tttgggtaat cgtaccaaca ctatccttca
     4441 atctgcattc ttccgtatca caggtgttat tcctgtagac caggctgttg aacagatgaa
     4501 gaaattcatc gttaagtctt acggtaagaa gggtgaagac gttgttaaca agaactatgc
     4561 tgccgttgac cgtggtggtg aatacaagac tttagctgtt gatcctgctt gggctaacct
     4621 gccggatgat gcaaaagctg aaaacaacga tcctgcattc atcaacgaag tagttcgtcc
     4681 gatcaatgca caagatggtg acttgctgcc tgtatctgca ttcaagggta tcgaagacgg
     4741 tacttggtat caaggtactt ctaaatacga aaaacgtggt gtagccgcat tcgttcctga
     4801 atggaatcca gaaaactgta tccagtgtaa caagtgtgca tacgtttgtc ctcacgcttc
     4861 tatccgtccg ttcgtactcg atgctgaaga gcagaagggt gctaagttcg aacaattgaa
     4921 agcagtaggt aaagtattcg acggtatgac attccgtatc caggttgacg ttctcgactg
     4981 tctgggttgc ggtaactgtg ctgacatctg tccgggtaat ccgaagaagg gtggcaaagc
     5041 attgacaatg aaacacctcg aaagccaatt ggctgaagct gacaactgga cttactgtgc
     5101 tgaaaacgtg aagactaaac aacatcttgt tgatatcaag tctaacgtga agaactcaca
     5161 gttcgctact ccgttgtttg agttctctgg tgcttgctct ggttgtggtg aaactccgta
     5221 tgtgaaattg atttctcaat tgttcggtga ccgtgaaatg gttgctaacg ctaccggatg
     5281 ttcttctatc tactctggtt cagttccttc tactccgtat actacgaacg aaaacggtca
     5341 cggtcctgct tgggctaact cactgttcga agacttctgt gaattcggtt tgggtatgga
     5401 attggctaac gaaaagatgc gtgctcgtat cgtgaagtta ttcaacgaaa tccttgctgc
     5461 cgacaacgct tcacctgaag caaaagaagt gctgaaagca tggattgaaa acatgtacga
     5521 tgctgacaag actaaagaat tggctcccca agtgaaagca gtgattgaag aaggtctttc
     5581 tcacggatgt cctatttgca aagaactgaa aggactgact caatatcttg taaaacgcag
     5641 ccaatggatc attggtggtg acggtgcttc ttacgatatc ggttatggtg gtcttgacca
     5701 tgtaatcgct tccggtaagg acgttaacat cctcgttctg gatactgaag tttactctaa
     5761 cacaggtggt cagtcttcta aggctactcc ggtaggtgct atcgctaagt tcgctgctgc
     5821 tggtaagcgc gtacgtaaga aagacctcgg tctgatggct actacttacg gttatgtata
     5881 tgttgcacag atcgctatgg gtgctgacca agctcaaact ctgaaagcta tccgtgaagc
     5941 tgaagcatat ccgggaccat ctttgattat cgcttacgct ccatgtatca accacggtct
     6001 gaaagcaggt atgggtaaga gccaggaaga agaagaaaaa gctgttaagt gcggttactg
     6061 gcacttgtgg cgttacaacc c
//
