LOCUS       c00054_gnlPro..        14036 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IOBNKCLI_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:56:21
            Original ID  :: gnl|Prokka|IOBNKCLI_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14036
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14036
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1077:4036]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1078..4036
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14036
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14036
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..593
                     /locus_tag="ctg54_1"
                     /transl_table=11
                     /translation="TIGQLVASIPSDKSIFLLGRYSFDDYYLSFMYQSIKEGNRFYYVI
                     GGQKIEFLTVHKSKGLEADYVILLQCNKDTYGFPSLVSDDPVLNYVLTKSDQFPYGEER
                     RLFYVAITRAKMKTLVLYDKRFPSVFVDEFLHPEKVSEESYVKHPNANKRWTRSADQFL
                     LKLHNEGKSVKYIANKMGRSQTSIVMRLNKLNQ"
     CDS             complement(638..865)
                     /locus_tag="ctg54_2"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCLSAIN
                     AENQQIVKQAPNFTPKSVKLGAFVLFKIYT"
     CDS             1078..3306
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_3"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             3311..4036
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_4"
                     /sec_met_domain="Radical_SAM (E-value: 8.6e-31, bitscore:
                     99.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTVAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(4269..5531)
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATTPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(5583..6131)
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             6319..7071
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(7176..8174)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg54_8"
                     /sec_met_domain="LysR_substrate (E-value: 9.3e-47,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.9e-18, bitscore: 55.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTTIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             8244..8717
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8821..9819)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_10"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.2e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9874..11142)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_11"
                     /sec_met_domain="MFS_1 (E-value: 3.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(11392..12405)
                     /locus_tag="ctg54_12"
                     /transl_table=11
                     /translation="MNRHLNFMTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVMVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVAGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWFAVDRSTWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(12428..13564)
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 atacgatagg gcaacttgtg gcttctattc catcggataa atcaatattc ctattagggc
       61 gttattcttt tgatgattac tacctctcct ttatgtatca atctataaag gagggtaata
      121 gattctacta tgtgatagga ggacaaaaaa tagagttttt gaccgtacat aagtcaaaag
      181 gtcttgaagc agattatgta atactattgc aatgtaacaa ggatacttat ggcttcccgt
      241 ctcttgttag tgacgaccct gtgcttaact atgtactaac taaaagcgac caattcccat
      301 atggagaaga acgtagattg ttttatgtag caataacaag ggcaaagatg aaaactcttg
      361 tgctatatga caagcgtttc ccctctgtat ttgtggatga atttttgcat cctgaaaagg
      421 tttcagaaga gagttatgtg aagcacccca atgccaataa aagatggaca agaagtgcag
      481 accaatttct attgaaactg cataatgagg gtaagagcgt caaatatatt gcaaacaaaa
      541 tgggcagaag tcaaacgtca attgttatgc gattgaataa acttaatcaa taataatgct
      601 ctatttttac ccaataacat tggttgtgtc cctattttca agtataaatc ttaaataata
      661 caaaagcacc caattttaca ctcttgggtg taaaattggg tgcttgtttt acaatctgct
      721 gattttcagc gtttattgcg gagagacagg gattcgaacc ccgggtacct cgcagtacaa
      781 cggttttcaa gaccgccgca atcgaccact ctgccacctc tccagaacta cggttaagta
      841 gtgcttttct cttaaagcgc tgcaaaggta cgaatcattt tttaacttgc aaattattcc
      901 gcaaaaaaat attagaaaag tatatttgga agtaataacc gccctctggc ttctccccat
      961 aaataggtat ttttatgcta ttcaacataa aataggaccc ttttatatac ctaaaccgaa
     1021 aaaaggttgt aaatttgcgc gctctaaagg ataactaacc actaactgat taattttatg
     1081 gaactgaata agacctttaa agatggactt tggagcaaag aaatcaatgt aagggatttc
     1141 gttagtaaca acatcactcc ttatgaaggg gatgcttctt tcctgcaagg acctaccgaa
     1201 cgcaccaaag ctgtctggaa tcactgtctc aaagctctcg aagaagagag aaacaataat
     1261 ggtattcgtg cactcgacta cacaactgta tctactataa cctctcaccc tgccggctac
     1321 atcgataaag agaacgaact gatcgtcgga ctacagaccg atcaggtgtt aaaacgtgcc
     1381 atcaaaccgt ttggcggaat caatgtggtt atgaaagctt gccgtgaaaa cggagtggaa
     1441 gtagatgaca gagttaagga tatcttcact cactatcgca agactcataa tgatggggta
     1501 ttcgatgtgt ataccgaaga aattcgttcg ttccgttcat tgggattcct taccggactt
     1561 cccgacaact atgcacgcgg acgtatcatc ggtgattatc gccgcctggc tctctatggt
     1621 cttgaccgtc tgatagaagc taaaaaagaa gatctgcata atctgacagg tcctatgact
     1681 gaagcccgca ttcgtcttcg tgaagaagta gccgagcaaa tcaaggccct gaaagagatt
     1741 aaagtattgg gcgaatatta tggtttggat ctgagccgac cggcatatac cgcacaggaa
     1801 gctgtacaat gggtgtatat ggcttatctg gctgccgtaa aagagcagga tggtgctgcc
     1861 atgtcactgg gtaatgtatc ttcattcctc gacatctatc ttgaatatga attaagccag
     1921 ggtacgataa ccgaaacatt cgctcaggaa ctgatcgacc aattcgttat caaactccgt
     1981 atggtacgcc acttgcgtat gcagtcgtac aacgatattt ttgcgggtga tcccacatgg
     2041 gtgaccgaat ctatcggtgg acgtttcaat gatggacgta ccaaagttac taaaacttct
     2101 ttccgcttct tgcagacact ttataactta ggcccgtcac cggaacctaa catgactgta
     2161 ctatggagcc ctgagttacc cgaaggtttc aaagcattct gtgcacaagt atctatcgac
     2221 acttcttccg tacaatacga aaacgacgac ctgatgcgtg aagtccgtca atcggatgac
     2281 tacggaatcg cttgttgtgt ttcatatcag gaaatcggaa agcagattca gttcttcggc
     2341 gcacgtgcca accttgccaa agccctgcta ctggccatca acggaggacg ttgcgaaaat
     2401 acaggtacag ttatggtaaa agacatccct gtattgaccg gtgaaacact gaagttcgaa
     2461 gaagtaatgg ccaactataa gaaagtattg atacaaattg cacgtgtata caacgaagca
     2521 atgaatatca tacattacat gcacgataag tattactacg aaaaggcaca gatggctttc
     2581 gtggatactg atccccgcat taacctcgct tatggtgtag ccggactttc aatcgccatc
     2641 gattcactgt ccgccatcaa atatgcacat gtgaaagccc gtcgcaacga catcggactg
     2701 acggagggat tcgatatcga aggtgctttc ccttgtttcg gtaatgacga tgaccgtgta
     2761 gaccacctgg gtgtggacct ggtatatttc tttagcgaag aattaaagaa actccccgta
     2821 tataagaatg cccgtcctac cctttcactg ctgactatca cttcgaacgt aatgtatggc
     2881 aagaagaccg gcgccactcc tgacggacgc gccaaaggca ttgcctttgc tcccggtgcc
     2941 aaccccatgc acggacgtga taaaaatggt gcaatcgcct cactgagttc tgtagccaag
     3001 ttgcgttatc gcgactcaca ggatggtatc agcaatacat tctcaatcgt tcccaaatca
     3061 ttgggagcaa cacaagaaga ccgtatcgac aatctggtga ccatgatgga cggatatttt
     3121 acaaaaggcg cacaccacct gaacgtaaac gtgctgaacc gggaaatgtt gcaggatgcg
     3181 atggaacatc ccgaaaagta tccgcaactg actatccgtg tctcaggata tgccgttaat
     3241 ttcgtgaaat tgagccgcga acatcagttg gaagtaatca gccgcagttt ccacgaaaga
     3301 atgtaattga atgataaacg tacactcata cgagtcaatg ggaacattcg acgggccggg
     3361 tctccggctc gtcgttttcc ttcaagggtg taacttccgt tgcctctatt gtgccaatcc
     3421 ggacacaatt gaagccaaag gagggacagc aaccgaccct gaggaaatag ttcgcatggc
     3481 cgtcagtcag aaagctttct tcggtaaaaa gggaggtatc accttttccg gcggagagcc
     3541 tacttttcaa gcaaaatcgc ttatcccact ttttaaaaga ctaaaggaag caggaatcca
     3601 tatttgcctt gataccaatg gcgggctatg gaacaatgat gtagaggaac tattggaatt
     3661 gactgatctg gttttattag atatcaaaga atttaatccg gaacatcatc agtctttaac
     3721 cggaagaagc aacgagcaga ccctgaaaac cgtagcctgg cttgaaacca atcataaacc
     3781 attctggttg cgatacgtat tagtgcccgg ctacagtgac ttcgaagacg atatccggca
     3841 gctgggagag catcttggaa cgtaccagat gattcagcgt gtagaaatat tgccttacca
     3901 caccttgggt gttcacaaat atgaagcaat gaacaaagaa tatatgctga aaggagtgaa
     3961 agagaatact ccggagcaga tagaaaaggc tgagaaacta ttcaggcaat atttccggac
     4021 cgtacaagtg aattgactta tataagtgtc gaaactcgta ttcgccacag attacacgaa
     4081 tttacacaga taaagattca ttggccatca atagattaag ttcactctgc ggtgaattat
     4141 gacgattgcg cttatttata attttgtaag tcacgacata aaaatctccc tgttcttgcc
     4201 tcaattcatt acaatacaag gcaagaacag ggaaataatg taaccggcat attttttgcc
     4261 accctacttt aataagtgaa tcgcaatcct gcctgcaagt taaagttaca aggcctttct
     4321 tttcggatgg tttgtacttt ggagccatca tcaaagaaat acgaaactcc cggttccaca
     4381 tataggccga catgatctgt cgcattgaat tgcgctccca cggcaccggc tacagaaaat
     4441 tgcaaaggct tcacattcac cttatcatcc gccaactttc cataaacaca cttttcaacc
     4501 attcctccgg cagatacata gagtgtaaaa tatttctttt ccagaaaatt ccagtttcca
     4561 cgtacaggaa tacctatata atgcaatttc tgactctgca tcttggtatc cccctgccgt
     4621 ttgatgtcag aagacaacaa cgtataagtc aatcccgtct ctacagagaa acctttggga
     4681 agagacttac gtacagacag tccgaagcta accggctgat gatgttcata atccaccacg
     4741 gcagttgtat tggacttcag gtaaggaacc ccttcctcaa atataacttc ctgatcggca
     4801 ggaatactca cagctccatt catgatcgtc atcaagtcga ccctgttagt catcggacgg
     4861 ggcgcaaaat tttcggaacc atttgtcgga agtccacctc cattaccgat acccactccc
     4921 atcgaccatt taccaccacg tttagcagaa gagtctccga taggcaactg atacttgtct
     4981 ttaccggacg gtcgccgcgc ttctttcctc tttggaggct gcgccgtcgc actttctttt
     5041 ttctcgattg cagcagttgc ttcctgttgc ggctcagctc tcttttcctc cgtcactgcc
     5101 tccggtcgct tctctgccag ggaggatacc tccggaacaa tcaccggatc agtatttttt
     5161 gccaaatagc ccgaaacagg gttgatgctc gtcgttccta ccggcttaac gggttcggat
     5221 acagctacct gtacatccgg caaggcaggt tccggcaata catccgggtt gacagccagt
     5281 gaaggagtcg ttgcataacg gatttcatca gctaccggac tattcagaaa atacaaactg
     5341 acagcagtcg ttaccaccaa taccacagct gccgcagcaa ccgcccaccg gcgatacgga
     5401 tatattcgtt tttcggttac aggcatcagt tccctttcca gtcgttccca accggaagca
     5461 ggcatcggct ccgaataatc ttcgagctta tccttgaatg ctttaatcca tttttcgtct
     5521 tctttcatca ttctatttca tttttgaaat ccaaggttca cctcagtatc tgtaaataca
     5581 tgtcaaccat tggtcaccaa ccattctttc actttctttg ccaatacact ttttgcgcga
     5641 aaaagctgtg aggcagaaga tttttcatta atccccaaca tctgtgcgat ttccttgtgc
     5701 gacttatctt caaaggtgta taaattgaat acggtacgat atccggcggg gagttcatta
     5761 ataaattgca tcagcacttt ctgtggtatt gcttcaacag ccgaagcatc cggttcttca
     5821 tacgtttcgg gaacttcatc cagtgccgtg gtctggttca tcacgtcgtt ctttcttaag
     5881 aactgtaaag ccgtattcac cattacacgc tccatccatg ctctcagaga gccttcaccc
     5941 cgccaggtaa acttgtcgaa ggagtcgaaa atcttcagga aaccgtcgtg taccaagtct
     6001 tgtgccatgt ctctgtctcc ggcataacga agacagacac caagcatgcg ccctgcgtac
     6061 tgctcataaa gttctttgcg ggcacgatta tctccctgcc tgcaacgttc cgacagctct
     6121 aactcattca ttctcctaaa cacgtgttta ccttataaat gcagcaaaga tagaaatact
     6181 gcacagagag aacaactctt ttatcacttt tgtttcttta acattttagg atgcaatatt
     6241 tcatcacttc ctgcattttt tcaatacaat aaagaataaa tctcaatgga taaataggat
     6301 aaaaccaaca agaaacttat gaagaaattt aatttaataa cttttgccgt catcctgatg
     6361 ttattgccca tattacagtc atgtctggac gatgccaaca acgacgagtg ggtcacttgt
     6421 cctccgggtg gaatattagc catcggcaca atgaagattc ccaatgcgga cactccaagg
     6481 gactttttca ttgcgttgga caatggagac aatgtacttc cggcagatac ggccgatata
     6541 cgcaacagga aatacactgt tgcagaaggt caaagagtct tcgttggcta tctgcagatg
     6601 ggaaaagaga agcccggata tgagaacggt aaaatattca cgatagaaga tatattgacg
     6661 aaagagatca tcccactgac ggaagctaca gcagacagca ttggagacga ccgtatcaac
     6721 gtcacagcgc atgcacttac gaaagattat ctgaccatcg aatatcaata tctgggcagc
     6781 atgaatgaaa ataaaaaaca catgctgaac ttggtacaaa acgaaataac aggtcccata
     6841 aaagatgacg gatatatcta tctggagttc cggcataatg cctttaatga ctcccccaat
     6901 caattgggtt cgagccttgt ttctttcaag ctggatagta tagccgagca attggcgaca
     6961 gccaaaggaa taaaactccg tgtgaacacc atttatgaca atatacagta tgtcacaata
     7021 gatatcaacg aagacaaaaa tttaaaaata aaatcatttc attctcaata aaacaacaag
     7081 aaacacctac acaatcaggc aaaacgagta ataattctga tacataaaag aaataaggcg
     7141 gcgatgtttg tgaaaatatc gccgtcgttt ttatattata ccaggcactg aacggcctgc
     7201 agggtaagca tctccttggg aaccgccgcc tgaatctcct ctttcaaaac ctgcagcaga
     7261 ctggtgcgga tgaagtcttt ccgggtcacc aggacaatct gacgggtagg ccgcgggata
     7321 gcaaacggac ggaccagttc tttctgctct tcgctcaatt gcatcactgc cagttcggga
     7381 ataaacgtaa tccccttacc actctccacc atatgcataa aggtttccat actacccagc
     7441 cgatacgcca tttggctgat cttaaccgct tccatctgac aaaaacgaac caactgatcg
     7501 cggaagcaat gcccttcgtc aagaagccaa agccgttccc ctgtcacatc ggacgtacga
     7561 atcacatcgt gcttgaacaa cggttccttc tttgagacat agcccaggaa ttgctcgtag
     7621 aataaggtct cttccgttaa tgcggcatca tccagcatgc tggcaatgat agcagcatcc
     7681 gcttcaccgg tcagcagagc cttgcgaatg tcgggcgtct tcatctccat cacccgtata
     7741 tcaagatccg ggtatttctc catcagttgc ggaaagaaac ggggcagaag ataaggtgca
     7801 atcgtcggta acactgccaa tcggaatgta cccgacaggg agtgctgttc ttcgctgatg
     7861 atctccttga cacagataac ttccgaaaga atcttacggg cctgttccag cactttctta
     7921 ccaatggtag tagggcaaac cggtgtcatg ctacggtcga acagtttcac ccccaattcg
     7981 tcttccagct tttggatcat tgcactcaaa gtaggttgcg tcacccggca atactcggca
     8041 gctttagcaa aatgccggaa ctggtccaca gccagaatat attccaattg ttgtatagtc
     8101 atcgttctct gatttattaa agatatagaa tctatcaatg caaagataga aattttcagt
     8161 ttgacacgaa tcattttgtg ccgtatcttt gttccagata aaaagaagaa atatagtatt
     8221 aactcaaaaa aaacaatatc attatgaaga ctttaaatta tacacatttg gaagaaaaag
     8281 gagctaacac catcgtactg tcattacagc aactgcttgc cgattttcag attcattatg
     8341 caaacctgag aggatttcac tggaacatca aaggacacgg tttcttcgta ctgcacagca
     8401 agtttgaaga tttatataat ggagccgccg aaaaggtgga cgaaatagcc gaacgtatac
     8461 tgatgctggg aggaactccc gccaataaat acagtgacta tctgaagatg gcgcagatca
     8521 aggaagtgga cggagtgaat aaggccgacg acgctctgaa tcatattctc gaaacttacg
     8581 ggcatctgat tgcggaagaa cgtaaaatcc tgtctctcgc ctcttcacac aacgacgaag
     8641 taacagtggc catgatgagc gactacctga aagaacagga aaagatggtt tggatgctga
     8701 ctgcatacaa cggataacag ccgaaagggt gtagccatct gaccgaaaag gtgtagccat
     8761 acaagcaaaa gggtgtagcc atcccggcgg gatagctaca ccctttctgt tttattcgat
     8821 tcagatgata cttgtacgtt tggtaaattc aataatctcc ggaatgtatc cgaatgcgag
     8881 cccggtcact gtatccgcac acccataata gatggcaatc cgtccggtct ccgaatcatg
     8941 aagcgccgcg catgggaaac agacattagg cacatcaccc atacattcgt aatccttctg
     9001 aggtgaaatc agataaggcc ccgaacggaa ttttactttc cagggttgat cgatgtcaag
     9061 cagtgccgaa ccaaaactat acacaaaacc gttgcaggaa gccaatacac catgatagat
     9121 cagcaaccag ccttccgagg tttcaatcgg gataggccct gcaccgatct tggtacactg
     9181 ccaggcactg tcttcgaacg gagccggcga cataacatga cgatgacgtc cccagaactc
     9241 catatcggga gactcgctat agaaaatatc tccaaaagga gtatgcccat tatcactcgg
     9301 gcggctcaac atcgcaaaac gaccgtttat cttacgaggg aacaagactc cattccgatt
     9361 gaaaggaata aaggcattct ccaactggtg aaaagtaaca aaatcatagg tgtaggccac
     9421 accgatagta ggaccatgat agccattaca ccaggtcaca tagtagcggt cttcgataaa
     9481 gcaaacccgt gggtcatatc catagaccca ggttccaacc tcagcgtcat cacattgaaa
     9541 ctttaacggt tcttcgttga tatcccaatg aacagcatcc ttgctgaatc ccacatgcaa
     9601 acgcatgcga cgattagtat catcacaacg gaacacccct gcatagccat ccttaaacgg
     9661 aactacggca ctgttgaata tactgtttga agtagggagc aagtcgcgcg gaataatcgg
     9721 attggccgaa caacgccaca ctacatcttt acatcctgcc ggacgttctt cccaaggcat
     9781 agccggcaaa gcagcacctg caattttaat ttcttccatg attcgattaa attaatatta
     9841 tgtatatatc ttgtttatat tgaaaatctc tttttatttc ttctttccgt ccggatatgt
     9901 gaaaggtacc agccaagtca cgataaaagc cggtatggta gcgataagta cccagataaa
     9961 gaaatcgcga taacccagcc aatcgctcag gtatccgctc atcattccgg gaagcatcac
    10021 ccccagattc ataataccgg tagcaaaagc ataatgtgcc atctgatgtt tgccgggagc
    10081 cacttgctgc atcataaaga gcatcaatcc gacaaaacca aacccgtaac ccaagtattc
    10141 agacacaatg gccataccaa taatccatag atcggaaggc tggtaaaggg ctaacaggaa
    10201 atataccaag aacggaatat taaaagcgca acataaagaa aacaaagtct tccgaagtcc
    10261 gaaagccgaa atgtaataac cggccaaaag cgaaccgaga ataaaagctc ccgctccgaa
    10321 cgtaccatat accagtccga tatcctgagt gctgagtccc aatccaccat ccgcaaccga
    10381 cgctttcagg aacaacggta caatcttgat ggcatatcct tcggcaaacc ggtacaaaat
    10441 gataaagaca atgtagaaag caatatgttt tttttggaaa aaagagcgga tgacttccca
    10501 aagcatattc aatgcgtcac tcatcgtatt cacttcaccg gaagcgcctc ctcccgaagg
    10561 caaaatccgg atgtggtaaa gaccgatcag aatcataata cccgcacaca tcaacatgac
    10621 aatcatccag gcatgtacca ctccaaattc atccttcagc atacctgcca gccaaaccaa
    10681 gcctccgttg gcaagtatct tggccagatt ataaaaagct ccctgccaac cgatatactt
    10741 ggcttgctgg gtagcagtca gttcagtcag gtatactccg tcccccgcaa tgtcatgagt
    10801 cgcaccactg agagcaatga tccccatcag agcgatggca taacgaaaaa agtcgggcag
    10861 cggcagcgaa agtgctacca atgcaaatgc cagtccggta ataatttccg tagcgacaac
    10921 aaagtacttt ttcgttttaa acatttccag aaacggactc cataaaggct tcaatgtcca
    10981 gggaagcata atgagagaag tccagaaagc aatctgtgca ttcgacactt ccatatcgga
    11041 aaacataagg acagaaacca tcgaaagggc cacaaacggc aatcccatag caaagtaaac
    11101 agtaggcacc caacatacag ggcttatcgg ctttttattc atcagttagt tttttataat
    11161 aattccatcg gttaacaatt ccagtaagca aagatagggg atattaaaaa cataacccaa
    11221 gattacgaca agaagttgct ttcattattt aataatacaa ctcacccggg aaaactacta
    11281 acctctatca cccttttttt attaaacttt atcaatacga cacacgcaaa gaagcaccga
    11341 agactttcat ccccgatgcc tctcgccccc ttatctacaa tctaaacacc tctattgctt
    11401 cacatataaa tttatctcag caaacccggt ataattatcc ggagtcagac agtttattct
    11461 gaattccttt acattcggga taggtggttc gatggccgca tattgcggat cagccccttt
    11521 aaaatttctg aaagtcaaga ctctcgggta agtaacccac tcggtttcac cctctttccg
    11581 aaccttaatc tcagcacttc tcagattata acccgaaccg taggcactct gtttagtgac
    11641 cgaaaatccg gttaaggtaa caggtcggtc cagtagcgta ttccaccaac actctccggc
    11701 attagccact ccccatgtaa accaagtagt atttatctca ccgtcaatag ccagatgtgc
    11761 accatattta gcatcatcat cggcataaac attgctgcaa cttacactcc acgtacttcg
    11821 atctacagcg aaccaattcc cgggtttcgt ataactggta taaagcacgc tggtataaat
    11881 ccggatataa accgtcttca tagatgtact gacagcctgt tcgtccatgc ccgcaactcc
    11941 tttaagcgtc acgggaagca catatccgtc aggattagtc aacttttcta tattcttcaa
    12001 aacgacctga aaagatgaat cggccactgt ctgtcccgtt tttaagacaa cttcacttgt
    12061 ttcaatggta taattatctt ggggcaacaa cttacatttc gtcttattgg cagaattgta
    12121 agtatccact ttcagcgtat ctactcccaa agcggcagtg acatcccgcg taaccggctg
    12181 tacggcacac aattgtattt caaaatcaga acggtcggca gtagaggaat tgctcacaca
    12241 atccaccatt accgcagcac ccatttcggc ccccggtgca actcccgttc tgatatatat
    12301 cttttgatat ttgtccattt catcatcatc gttgctgcac gaagccaacg atacaaagcc
    12361 tgttatcagg cagattaagg tcataaaatt caaatgtcta ttcatatctt atcttctttt
    12421 tacatagtta ttgcttatca aaacgaacat gctctttcca gacaagagtt cctcctgcca
    12481 ccaaatcgta tccgtgtccg gtacagtcgg caaaggcatt tcctttacct tcatccattt
    12541 tccaatagcc tatcaggttc ggatcggcgg gtttcacggc aaaatacatg ttggactgaa
    12601 tttgcgtctg gctgattgcg ctcttccaaa gacgcacctg ggccatctga caattgttgc
    12661 ggaagtaact accgctcgaa accatgttca tcttgtcgaa tctaaccggg ccaccctttg
    12721 tctgcagagt cacgtcgagc actccgttga tataaatcga caataacccg gaagaattat
    12781 aaacgaaggc cagatgatac cacttattct tctcaaacaa agtcaccgta ttgacctgac
    12841 ttccaagtgt cttcacctgt aatgaattat aagggatcat agcgtcaccg aaacggatat
    12901 aaacctcgtg gtcgctgctg cccgaattaa atatagcctg attattaata tcgaatccgt
    12961 ccatctgtac ccaagcctcg agtgaccatt cattggttgt cactccccac aattcgtcct
    13021 tggcgggctt cacggcattg gtcgtattca taaacggtac agactgtatc agcggcttat
    13081 ccagcaaaat gataaacttc gacgaaagcc cgattgtgga caccggtccc tgaatttctg
    13141 tgagagatac cggaatagca tacaattctc cgttttcgtt tgaataaggt ttcactctaa
    13201 actcactggg gattgcgcta acatcgcctg ccgctatctt tatctctttg tcataagtaa
    13261 aatactgctc gggaaggact tcgtacgaag tttcattagc ttcattgtac tctttaagaa
    13321 tagaaggatc taccgtcagg acagcagtca cattttcggt tacaggctgt cccacacgta
    13381 cggtcagagt agttgttgtt acattttcag gatcaacggt aacctttgcc gaaccattct
    13441 cggatgcttc attcaaataa atcgcattgt cgataacctg gtaatcggca tcgttgcatc
    13501 ctgccaggat catcggcaga acgaaacagg caagcaaata ttgttttatt gttattcttt
    13561 tcataatcaa attctttaaa gtcattttac agcaggattc attattctga ttgcttcacg
    13621 caggtactta tattcgatgt cgcccggata gtcatattcc atgtgatagg tgcctactcc
    13681 acccttccgt acctgttttc cgtcaatagt cggagtccag cgtgccatgc cggcaagtgc
    13741 tctcattttg tttccgtaac gatctacata atcacctcct cctgtcggag cataagattc
    13801 gaaattctcc gtaacgatgt acatattagc cactttctcc ggaggaagta ttcctttaaa
    13861 gttggcaatc gtaccagcca gacgtctgtc aagattagcg tcggaattac ccgcaaggtt
    13921 agagtatgcc tgcacaatga aatagtcaaa gtaaggcccg gtttccggat gaatactttg
    13981 aggctcgcca tcaatcacaa gtaaccgtcc cgtacccgat ttaggtccga ttcttt
//
