LOCUS       gnlProkkaGDCDGBIC_77   12537 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDCDGBIC_77.
ACCESSION   gnlProkkaGDCDGBIC_77
VERSION     gnlProkkaGDCDGBIC_77
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 13:18:55
            Original ID  :: gnl|Prokka|GDCDGBIC_77
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12537
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12537
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2189:2537]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2190..2537
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12537
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12537
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(4..126)
                     /locus_tag="ctg77_1"
                     /transl_table=11
                     /translation="MKHISKAAITIKIMNNKYIFSYFELALIINFSKNLIWSAK"
     CDS             757..2145
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg77_2"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             2190..2537
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_3"
                     /sec_met_domain="PF05402 (E-value: 2.2e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.2e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(2527..2814)
                     /locus_tag="ctg77_4"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNNYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(2836..3900)
                     /locus_tag="ctg77_5"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(3974..4864)
                     /locus_tag="ctg77_6"
                     /transl_table=11
                     /translation="MDIQLSEEGIEETETNYEMLEIEEIRSLIKPRQQFAHKGNFGHAL
                     LIAGSKGMAGASVLAARACLRSGVGLLTVHAPLCNNDILQTSAPEAMVETDVSETCFAV
                     PTDTDDYQAVGIGPGLGRNEETEAALIEQLEHCQTPTVLDADALNILANHRHTLTHLPK
                     GSILTPHPKELERLVGKCQDSYERLMKACELAHTAKVHIILKGAYSAIITPEGKCYFNQ
                     TGNPGMATGGSGDVLTGVILALLAQGYPAEDAAKIGTYIHGLAGDIAQKKQGMIGLIAS
                     DIVTCLPTAWRLVSE"
     CDS             5120..5407
                     /locus_tag="ctg77_7"
                     /transl_table=11
                     /translation="MFRCQCGRYELGADFMESYFFHHLYQFFVGLAVGRKFAFRVEEIY
                     FDLVSFFRHHAGDGEGVSAIIARSGKDGDRCFRIPSVGDGFSQCLCGTFH"
     CDS             complement(5951..6511)
                     /locus_tag="ctg77_8"
                     /transl_table=11
                     /translation="MKAKEIGRASIKIEDSSNNMYILSVVVKYRTLTHKAFTAKVIVKG
                     DELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVL
                     DEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFLPLLNTRMNAHPLIQYCFVR
                     DLTAQYKQDYLALENAYLIQIAE"
     CDS             complement(7153..7299)
                     /locus_tag="ctg77_9"
                     /transl_table=11
                     /translation="MWVSPHLSKGKFNILNTGIEHSFFFSKQDFVFPCQPTDSNRYILE
                     RQT"
     CDS             7474..9018
                     /locus_tag="ctg77_10"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHILHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             9060..9596
                     /locus_tag="ctg77_11"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             9630..10199
                     /locus_tag="ctg77_12"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             10212..11378
                     /locus_tag="ctg77_13"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             11402..12187
                     /locus_tag="ctg77_14"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHEANCLLIGDAYLSASSQQRQEMLHGVDALITREL
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
ORIGIN
        1 tgcttacttt gcagaccaaa tcagattttt ggagaaattg attattaacg ctaattcaaa
       61 ataactaaaa atgtacttat tattcattat cttaatggtg attgcagcct tgctgatgtg
      121 cttcatcgtg ctgattcaga attcaaaagg aggcggactt gcttctggtt tttcttcatc
      181 aaacgctatc atgggcgtgc gcaagactac agattttctg gaaaaagcaa cttggggtct
      241 ggctatcttc atggttgtga tgagcgttgc tactgcttac gttgttcctt cttcttctgc
      301 ggctaaagat gtattgttgg aacaagcaca gaaagaacaa caaaccaacc cgtataatat
      361 gcctaccggt actgctgctc ctcagacaga tgctactgct cctgcagagt ctgcaccagc
      421 aacggaagct tcggctactg aaactcctgc tcctgcagca gaataattca gtgacaggat
      481 attcggttta aacttattga gtgaacgggc tttttgaccc gttctcttca ttataggcgc
      541 gaattacgcg aattacaaga gattctaata gaatcgtgta atacgtgtag ttcgcgcctg
      601 tctttattat tgggcccggt ctgctcttct tcatacagga atatccggtc agatgtcctt
      661 tttcttataa aatgttctcc ttttttagta aaacaaatga taattagtta actttgttgc
      721 ccgttacgag attattaact ccttttaaat attacaatga cagaacaatt gaaacaaaag
      781 ctgaatgact ccgcagtgct gcgttggagt gttctagcat tagtcgcttt taccatgttg
      841 tgcggctact tcctcacaga cgttatgtct cctctgaaac ccatgcttga aaaagaactt
      901 ctctgggaca gtttagatta cggttttttc accagtgctt atggctggtt taatgtattc
      961 ctgctgatgc tcatctttgg tggtatcatt ctggataaga tgggagtacg cttcaccgga
     1021 atgggtgcct gtttattgat ggtgttcggt tgtggattga aatattatgc tattactact
     1081 actttcccgg aaggtgcgat gcttttcgga ttcaagatgc aagtcacatt ggctgcattg
     1141 ggttatgcta ttttcggtgt aggagtcgaa attgcgggta tcaccgtttc gaagattatc
     1201 gtgaagtggt ttaaaggcaa agagatggct ctcgctatgg gactggaaat ggcgaccgcg
     1261 cgtattggaa cgactttggc catggtgctt accgttcctt tggcagactt cttcgggtct
     1321 acggatgaga gcggcgtatt ccataccaat attcccgctc ctattctgtt ctgtctcgtc
     1381 atgttgtgcg taggtaccat cgcattcttc atctatactt tctacgataa gaaactggat
     1441 gcttcactgg atgcggaagg actggaaccg gaagaacctt tccgcatgaa agacattgtc
     1501 tatatcatta ccaacaaagg attctggctg atcgcattac tgtgcgtatt gttctattcg
     1561 gctgtattcc ccttcatcaa gtatgcggcc gatttgatgg tacagaagta caatgttgat
     1621 ccgaaacttg cgggaacgat tcccggattg ctgccgattg gcgcgatcat cctgacaccg
     1681 ttgttcggtt cattatatga ccgtatcggt aagggagcca cgctgatggt gatcgggtcg
     1741 gtgatgctga ttttcgtaca cacgatgttc gctcttccta ttctgaatat atggtggttt
     1801 gcaacggtga tcatgattat tctgggattt gctttctcat tggttccttc ggcaatgtgg
     1861 ccttcggttc cgaagattat tccggagaaa cagttgggaa cggcttatgc gttgatcttt
     1921 tgggtacaga actggggatt gatgggcgtg cctttgctga tcggatgggt gttgaattct
     1981 tattgcaaag gtccggttgt agatggtgca cagacttatg attatacttt gccgatggct
     2041 atttttgcta tgttcggtgt acttgccctg attgttgcct tgatgctgaa agtggaaaac
     2101 aagaagaaag gctacggact ggaagaagca aatattcaga aataatcaca gtatatattc
     2161 tatctgaaaa gatataaaag agaaaagata tggctacgaa agagaaaata aacctcctgg
     2221 aggtgatccc ttgtcgtaac gaacatatta aagctgaaca ggaaggggag actattgtgc
     2281 tctccttccc tcgttttaaa cgttcgtgga tgagtcgtta tttattgccg aaaggaatgt
     2341 ccaaagatat tcatgtgcgt ctggaagaac acggtacggc tgtatggaac ctgatagacg
     2401 ggcagcggac ggttcgtgag attatagaaa aactcgcaga ccactttcaa tatgaagcag
     2461 gctacgagtc tcgtgtatct acctatcttt cccaattaca gaaagacgga tttattaaat
     2521 ggataattat ccattaaaaa agattgccca caggaggaca gcacatccta tcagtacgcc
     2581 cataatgatg agcgttcccc atacgaaata gttgttatct ttttcttttt tcttttccga
     2641 atccttgatg atgcgttcca tctcttccgg agtcgtatcc ggcagaagat aagggtcgtt
     2701 gtttcttcta agtcgcccta acttgtcatt tctccgttca cggcgtaagc gggaggcttc
     2761 tttgccgtct ttcagccgac gtatcatgtc gagcatatgt ccttcgccac ccatcgtttt
     2821 gtttttttag aggttttatt tgctttcttc tctatctact ttcagtagtc caccggtcac
     2881 cggatcaaag taaactttga tggtcgagtt cttgttgaat aataccggag caaggtattc
     2941 tatgataccg aactgagtaa caggtatttc tccttcatac aatttctttt tgccgtccgt
     3001 cagcgtcacc attgcctgtc ccggtacgtt ataagcaatg ccttccatct ctttcttctt
     3061 tttcccgtcc tcttgcggaa tcttcaccgt tttcaggtct ttcagactga tgtagaatgg
     3121 agtgcctgcc aaatcgttgt tggcaactat acccagcttc tttgaaaagc ggaaagctac
     3181 ctcattgtcg aattccttat ccggagtgag gcggacagta aatgtctttt cttctttatt
     3241 gcggactccc gaaaacatct cggtcatggc ttcttcctga agattcaggt tgtcgagcat
     3301 gattttgagc tgtgcgccgt ccgaaggcat attatctgct tgtccgcgca ataatgcgtt
     3361 tttactttcg cggatattat agatttcctt tgctaccagt tcggccatct tggcggttga
     3421 acttgccatc agaatttctt ctgtgagaaa gtcgcgggga ttggcttttc gttggggagc
     3481 aacggcattg tttgctgcat tctttgcatt gttactgctg taggggacat tgattgattt
     3541 gataagaccc tcttcagtca gttccataag aggagctacg gttttgtctt tcagtttgac
     3601 gaaataagta gcttcgctgt ttggtacacc tacaggtttc actttgacac tgttcagttc
     3661 ccagtattct tcgggttcgg cagagacgtt ggtcagtctc aggtagcggt cggcgtattt
     3721 gctgaattca cccggcttat agttgacttt gtttgctttt atttctattt ctatctgggt
     3781 tttggggagg gcgtacacta ctccgtagtc ttttcctcgc gtcactcctg tcagcacttc
     3841 ggtctgcgca taggcggaag ttgccattag tagtcctgtt gctatgatta actttttcat
     3901 attcggttct ttttagctga ttttgaaaaa caaagttaat gaagttattg aataaaccgt
     3961 aagttcttaa cttttattcg cttacaagtc gccatgccgt cggcagacaa gtcacgatat
     4021 cacttgcgat taatccgatc atgccctgtt ttttctgggc gatgtctccg gccaatccgt
     4081 gaatgtaagt accgatcttt gcggcgtctt cggcgggata gccttgcgca aggagtgcaa
     4141 ggattactcc tgtcagtaca tctccgctgc ctcctgttgc cataccggga ttaccggtct
     4201 ggttgaagta acatttgcct tcgggggtga taatggcgga ataagctccc ttcagaatga
     4261 tatgtacttt ggcagtgtgc gccagttcgc aggctttcat cagtcgttcg tatgagtcct
     4321 gacatttgcc gaccaggcgt tccagctctt tcgggtgagg ggtgaggatg gaacctttcg
     4381 gcagatgggt gagcgtatgc cggtgattgg ccagaatatt gagtgcgtcg gcatccagta
     4441 ccgtcggagt ctgacaatgt tccagttgtt ctatcagggc ggcttccgtt tcttcgttgc
     4501 gaccgagtcc cggaccgatg ccgacagctt ggtaatcgtc cgtatcggta ggtacggcaa
     4561 agcatgtttc gctgacatct gtttctacca tggcttcggg ggcggacgtt tgcagaatat
     4621 cgttgttgca taacggcgcg tgtaccgtca gcagacctac tcccgatcgc aaacaggcac
     4681 gggcggccag taccgatgca cctgccattc cttttgagcc ggctatcagc agggcatgtc
     4741 cgaagtttcc tttatgggcg aattgttggc gtggtttgat cagtgaacgg atttcttcga
     4801 tttccagcat ttcgtagttt gtttcagtct cttcgattcc ttcttcgctc agctggatgt
     4861 ccaataactc ccattcgcca acaaattctg tattttcggc aaagaggaag gccagtttag
     4921 gaagttgcag gctgaaagtg acgtccgcac ggataatatt gctttttaca ttgaatgtat
     4981 tttcttctcc catcagcccg gaagggatgt cgatggagac taccatggcg ggagaggcat
     5041 tgatatattt cacaacggca gcgaatcctc cgctcaatgg tttgttgagt ccggaaccga
     5101 ataatccgtc gatcacgaga tgttccggtg tcagtgtggg aggtacgaac tgggtgctga
     5161 tttcatggaa agttacttct tccatcatct ctaccagttc tttgttggtc tggcagtcgg
     5221 gcgaaagttc gcctttcgtg ttgaagagat atacttcgat cttgtatcct ttttccgcca
     5281 tcatgcgggc gatggcgagg gcgtctccgc cattattgcc cggtccggca aagatggtga
     5341 caggtgtttc cggattccat ctgttggtga tggctttagt cagtgcctgt gcggcacgtt
     5401 ccattaaatc tatggatgca atcggttcat gttcaatggt ataggcatct aacttcttaa
     5461 tgctgctgct tggaaatatt ttcattgcga tattctttta gttttcgacg cacaaactta
     5521 cacaaaaact ctgaattaat cctttattcc ggttggtttt cggctttttg ggaaggaact
     5581 tcaggtatta atacttgagt tgtcaggtat taatagttga tgtgtcagtt attaatagtt
     5641 gagaagtcag atattaatga ttgttatctc atttactttt actctctccg gagaacattc
     5701 atggctgttt gttaaccttc ccatgcgtgt ttctactact gtatattcct ctggttcacc
     5761 tctttcaccc gcaatcgcct tattcatcaa aggttcagga aaagggtgga agaggtgatt
     5821 gtgataaata tgctatgggc atattcttga ttagctaata gcttattgtt ttttgctaaa
     5881 tctaatgggg agtttgctca tataataaat actctattca ctctgctaaa gaagaaaatc
     5941 agtgtagctc tcattctgct atttgaatca gatatgcatt ttccagtgca aggtaatctt
     6001 gtttgtactg tgcggttaaa tctctgacaa aacagtactg aattaacgga tgagcattca
     6061 ttcttgtatt gaggagtggt agaaagttct tggtaatata gaaagtatca ataactttgc
     6121 cattatcttc tttgattgtt atacggtaat actcactcaa tttgtattca cctttgatgg
     6181 gaatggcatt ttcttcatcc agcactatat gttctttttc aaagttgcct gttttcatgt
     6241 tattatctga ataatacaaa tctactgttc ctttgctgtc ttccgcattc ataaaagtaa
     6301 atacatattt attaatcgga tatgaattgc ccactttgtt cattaactca gtgtgttctt
     6361 cagatgtaag ctcgtctccc ttcacaatga cttttgctgt aaacgcctta tgagtaagag
     6421 tacgatattt tacaacgaca gacagtatat acatattatt cgaactgtct tctatcttga
     6481 tggatgcgcg tcctatttcc tttgccttca atgttaaact tccgttgtgg tagtttactt
     6541 gtaccacttt ctcattctca ttggtcactt tgtaagttcc gtctccaccc ttgatgaaga
     6601 gtggtgtcgt ttctttgctg aacggagtca gtgtgtaaga acggctctcg ttgtcgaact
     6661 taatttgagg atcttcatat tccagagtga ttggagaaaa gttgtcatca ttgtcattac
     6721 agctcacgag gcaaataata caaaggaata acgaaagtat tcctgttagt tttttggtag
     6781 tcatgctaat taaagtttta aatgtgcgat attagtttag ttctcgtctg caaacttatg
     6841 aaaaagaatt gaactgtttc tttatttgtg ctatttttta gcagagatcg gcataaatga
     6901 ttagaatgta actaataata gcagctaatg ctttgattat ttgctttttt cgaaaaaaat
     6961 gatatctttg tagtgcagta atgtgcttta cgttattctc ctgtgctcac aatgtttaga
     7021 ttataaatat aaattgttta atcttctaaa gtttgcatga tggaaaagaa aagaattggc
     7081 tcaaatgccg ggaaagtatg gcgcatctta aatgaaaagg gcgaacagtc tatgttcact
     7141 ttgtgccatg agttaggttt gacgttcgag gatgtagcga ttgctatcgg ttggctggca
     7201 agggaaaaca aaatcctgct tagaaaaaaa gaaggaatgc tctatgccag tattgagaat
     7261 gttgaattta cctttggata aatggggact gacccacatt taaggagaat atccacttga
     7321 ttatttacac tgttgaaaac ataataaggt gggtaactga gacttcttgc acgccatcct
     7381 gtatttttct attccataag aatcttcttt tttgaggcat ttaatctact ttttagtacc
     7441 tttgcgcccc ataaactact aaacacataa ttcatgagtt cattgaaagg gcatccgaaa
     7501 ggcctttacc taattttcgc aacgagcacg gcagaacgtt tcagttacta cggtatgcgt
     7561 gctatcttta tcctctttct gacgcaggca ttgctttttg ataaagaagc ggcggcctct
     7621 atctacggta gctacaccgg actggtctat ctgactccgt tgatcggcgg atacattgcc
     7681 gataaatatt ggggtatccg tcgttcggta ttttggggag cggtgatgat ggcagtcggt
     7741 cagttcctga tgtttatgag tgcctcttca ctgaacaata cagaccttgc ccactggctg
     7801 atgtatggcg ggctcggatt catgatttta ggtaacggtt gctttaagcc taccgtttct
     7861 tcgctcgtcg ggcaattata tgaacccggg gacaaacggt tggatgctgc atacaccatt
     7921 ttctatatgg gtgttaatgt aggttctttc gccgctcctt tgatttgcgg tttcttggga
     7981 gacacaggga atccgcagga ctttaaatgg ggattcctcg catccggaat catgacgctg
     8041 ttcactgttg tcctctttga aactcagaag aataaatacc ttttctctcc ttccggtgaa
     8101 ccgattggta tcgtccccga cgccagacgt gaaaaaaagg aggataaagc cgaacatatt
     8161 ttacatccga agatggacaa acgtaccaaa gtacgtaata tcatcatcat tactgccctt
     8221 acggttgcct taatagcctt ttttagctat gcctttagcg atgactggat tagtgtgggt
     8281 atctttacgg cttgtattgt ctttccagtg ctcattctgc tggatggttc attgaccaaa
     8341 gtagaacgta gccgtatttt cgtaatctat atcgtagctt tcttcgtcat tttcttctgg
     8401 gcagcttacg agcaggcagg agcttctctg acattattcg cttccgaaca gactgaccgc
     8461 agcattttcg gctgggagat gccggcttcg tggttccagt cattcaatcc gctttttgta
     8521 gtgatccttg cctatattat gcccggtata tggggctttc tgaataagcg aaacatggaa
     8581 ccggcttccc ctaccaaaca ggcaatcggt ctgttgctgc tttctcttgg ttatctcttc
     8641 atctgttttg gagtgaaaga tgctattcca ggagtaaagg tgagcatgat ctggctgaca
     8701 gggctttact ttattcatac aatgggagaa atcgctctgt cacctatcgg gctttctatg
     8761 gttaataagt tgagtccgtt acgtttcgcc tccttgatga tggggatctg gtatctttct
     8821 accgccaccg caaataaatt tgcaggtatg ctgagcggcc tctatcccga agacggaaaa
     8881 gtgaaatcaa tccttggtta tcagatcgct accatgtacg acttcttcat gctgttcgtc
     8941 attatgtccg gtgttgcctc actgattctg ttccttctct cgaagaaatt acagaagatg
     9001 atgcacgggg tagaataaaa aattgtattt ttgcgacaac ttttttaaaa tgaccggtta
     9061 tggataccat acagataaaa gacaagcaat ttactgtttc cattaaggaa caggatattc
     9121 aaaaagaagt gattcgcgta gcgaacgaaa tcaatcgtga tttggcaggt aagaatccgc
     9181 tcttcctcag tgtgttgaac ggctcgttca tgtttaccgc cgacttgctg aagcatatta
     9241 cgattccgtg cgaaatttca ttcgtgaagt tggcatctta tcagggggtg acttccaccg
     9301 gagtaattaa agaagtgatc gggctgaatg aagacattgc cggacgtacg gtagtgatcg
     9361 tagaagatat tgtagatacc ggactgacga tgcagcgtct gctggataca ctgggcacac
     9421 gcaaccccga agcgattcat atcgcctctt tgctggtgaa accggaaaag ctgaaggtca
     9481 atctgaacat agaatacgta gcgatggaaa taccgaatga ttttatcgtt ggctacggat
     9541 tggattatga tggtttcgga cgcaattatc ccgatattta tactgtagta gattaaattc
     9601 aaatacaaat taatttttag gttaaaaaga tgttgaacat tgtaattttc ggtgctccgg
     9661 gttcaggaaa aggaacgcag agcgaacgta ttgtagaaaa gtatggaatc aaccacatct
     9721 cgacaggaga tgtattgcgt gcagaaatca agaacggcac ggaactgggc aaaactgcta
     9781 aaggttacat cgaccaggga cagttgattc cggatgaatt gatgattgat attctggcaa
     9841 gcgtattcga tagcttcaaa gacagcaaag gtgtaatttt cgacggtttc ccaagaacaa
     9901 ttgcacaggc ggaagcatta aagaagatgt tggcggaaag aggacaggat gtttctgtaa
     9961 tgttggatct cgaagttccg gaagatgaac tgatggtacg tctgatcaaa cgtggcaaag
    10021 actccggtcg tgccgacgac aacgaagaaa caatcaaaaa acgtctgcat gtatatcatt
    10081 cacagacatc tccgctgatc gactggtaca agaacgaaaa gaaataccag catatcaacg
    10141 gtctgggtac tatggatggt atcttcgctg atatctgcga agcagtagac aaattgtaat
    10201 aaataaaaaa tatggctgaa tcgaattttg ttgattacgt aaagatatac tgtcgctcag
    10261 gcaagggcgg aagaggctct acgcacatga ggcgcgagaa atattgtcct aacggaggtc
    10321 ccgatggggg cgatggtgga agaggaggcc atattatctt gcgcggtaac cgtaattact
    10381 ggacattgct tcacttgaag tatgaccgtc atgcgatggc aggtcatggc gaatcgggca
    10441 gcaagaaccg tagtttcgga aaagacggtg cggataaagt gatcgaagta ccctgcggaa
    10501 cggtagtgta taacgccgaa accggagaat acctttgcga tgtgacggac gacggacagg
    10561 aagtgatctt gctgaaaggc ggtcgtggcg gtcagggcaa cagtcatttc aagacggcta
    10621 cccgtcaggc tccgcgcttt gcgcagccgg gcgaaccgat gcaggaaatg acggtgatca
    10681 tggagctgaa actgttggca gatgtaggac tggtaggttt cccgaatgcg ggaaagtcta
    10741 cgttgctttc tgccatttcg gctgcgaaac cgaagattgc cgattacccg tttacgacac
    10801 tcgaaccgaa tctgggaatt gtttcctatc gcgatggaaa gtcattcgtg atggcggaca
    10861 taccgggcat catcgaggga gccagtcagg gaaaaggatt gggactgcgg tttctgcgtc
    10921 atatcgagcg taactcgttg ctgttgttca tggttccggc agatagcgat gatatccgca
    10981 aggagtatga agtattgctg aatgagctgc gtacgttcaa tcccgaaatg ctggacaaac
    11041 aacgtgtgct ggctatcacg aagagcgata tgctcgatca ggagctgatg gacgagattg
    11101 aaccgacatt gcccgagggt gttccgcata tattcatttc ttctgtttcc ggtttgggaa
    11161 tctcagtgtt gaaagacatt ctgtgggagg aactgaacaa ggaaagtaat aagatagaag
    11221 acattgttca ccgtccgaaa gacgtgaccc gtctgcaaca ggaactcaag gacatgggcg
    11281 aggatgaaga actcgactat gaatatgagg aagacgctga cgacgacgat gatgatctcg
    11341 actacgaata cgaagaagag gattgggaag aaaaatgatt tcaatcacaa gagataaaag
    11401 aatgttgggg tatgagtcgt taagctcata ctccaacatt tctcattttg taactacccg
    11461 gcagggaggg tgcagcgaag gaaattatgc gtcattcaac tgtacgccct acagtggaga
    11521 cgaggcggaa aaggtccggc ggaatcaaac gcttctgatg gaaggaatgt cgcagacacc
    11581 cgaagaactg gtgattcctg tgcagactca tgaggcgaat tgcctgctga tcggggatgc
    11641 ttatttatcg gcttcgtctc aacaacgaca ggagatgctg cacggagtgg atgctttgat
    11701 tacccgcgag ttgggatatt gcctttgcat ttctactgca gattgtgttc ctgtgttgat
    11761 atatgataag aaacatagtg ccatagctgc cattcatgcc ggatggagag ggacggtagc
    11821 atacatcgtg cgtgatactt tgttgcggat ggagaaggag tttggcacaa gtggagaaga
    11881 tgtgatagcc tgtatcggtc cgagtatctc attggcttct tttgaagtgg gtgaggaagt
    11941 gtacgaagca tttcagaaga atggttttga tatgcctcgt atttctatca ggaaagagga
    12001 aaccggaaaa catcatatcg acttgtggga agcgaaccgg atgcaaatcc ttgctttcgg
    12061 tgtgccgtcc ggacaagtgg agcttgcccg gatatgtacg tatattcatc acgacgagtt
    12121 tttctcggca aggcgtttgg gcattaagtc cggacggatt ctgtcgggga tcatgattca
    12181 taaataatag acttgaacgt aagttgatat aaacttgaat aaaagtatgt ttgaaataaa
    12241 agtatctcag gaaataaaga acgcctgccc tgtttttgcc ggagcagccg tatatgcagc
    12301 agtgaagaat actgcttatt gcgatggact ttggaaagaa ataaatattt tcacagaaga
    12361 cttgactacc accacccaaa tggcagacat taagttgcaa cctgtgattg ctgctacccg
    12421 tgaggcttat aagcgttgcg gaaaagatcc ggggcgttat cgtccgtcgg cagaagcgct
    12481 gcgccgtcgc ctgatgcgtg gcatcccttt gtatcagatt gatactttgg ttgacct
//
